CN105056288B - Medical hemorrhoid biological hydrogel functional dressings and preparation method thereof - Google Patents
Medical hemorrhoid biological hydrogel functional dressings and preparation method thereof Download PDFInfo
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- CN105056288B CN105056288B CN201510529552.6A CN201510529552A CN105056288B CN 105056288 B CN105056288 B CN 105056288B CN 201510529552 A CN201510529552 A CN 201510529552A CN 105056288 B CN105056288 B CN 105056288B
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Abstract
The present invention relates to technique in skin care fields more particularly to medical hemorrhoid biological hydrogel functional dressings and preparation method thereof.Medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：Chitosan quaternary ammonium salt 8 ~ 12%, polyhexamethylene guanide 0.1 ~ 0.2%, bright rock 0.15 ~ 0.23%, glycerine 12 ~ 18%, star anise oil 0.08 ~ 0.12%, allantoin 0.2 ~ 0.4%, Co-Q10 0.3 ~ 0.6%, ceramide 0.15 ~ 0.25%, peppermint 0.3 ~ 0.65%, purifying water surplus.The present invention can be used for repairing and improve internal piles, external piles, mixed hemorrhoid and anal fissure, the symptoms such as caused bleeding, pain, rectal tenesmus after anal fistula operation, haemorrhoids is promoted to reduce, haemorrhoids prolapsus is prevented and mitigates the symptoms such as hemorrhoid mucous membrane congestion and edema, also it can be used for the nursing of the anal disease treatments such as hemorrhoid, and it is easy to use.
Description
Technical field
The present invention relates to technique in skin care field more particularly to medical hemorrhoid biological hydrogel functional dressings and its preparations
Method.
Background technology
With the development of society, the pressure of people is increasing, regular overtime work causes the time sat too long, very
Hemorrhoid are easy to cause, in order to quickly treat hemorrhoid, many people are treated using injection, however injecting treatment can bring some pairs to make
With, and hospital is often run, cause inconvenience.
The content of the invention
It is an object of the invention to solve the deficiencies in the prior art, a kind of medical hemorrhoid biological hydrogel functional dressings are provided
And preparation method thereof, hemorrhoid can be effectively treated, and it is easy to use without side-effects.
In order to achieve the above objectives, the technical solution adopted by the present invention is：
Medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 8 ~ 12%
Polyhexamethylene guanide 0.1 ~ 0.2%
Bright rock 0.15 ~ 0.23%
Glycerine 12 ~ 18%
Star anise oil 0.08 ~ 0.12%
Allantoin 0.2 ~ 0.4%
Co-Q10 0.3 ~ 0.6%
Ceramide 0.15 ~ 0.25%
Peppermint 0.3 ~ 0.65%
Purify water surplus.
Preferably, medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanide 0.15 ~ 0.2%
Bright rock 0.18 ~ 0.21%
Glycerine 14 ~ 16%
Star anise oil 0.09 ~ 0.11%
Allantoin 0.25 ~ 0.35%
Co-Q10 0.4 ~ 0.55%
Ceramide 0.18 ~ 0.21%
Peppermint 0.4 ~ 0.6%
Purify water surplus.
Preferably, medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanide 0.2%
Bright rock 0.2%
Glycerine 15%
Star anise oil 0.1%
Allantoin 0.3%
Co-Q10 0.5%
Ceramide 0.2%
Peppermint 0.5%
Purify water surplus.
Its cure mechanism：
Water speed dissolved cation chitosan quaternary ammonium salt has good antibiotic property, film forming, Cation adsorption, moisture-absorbing moisture-keeping
The performances such as property, flocculability, antistatic property.Its anti-microbial property is better than chitosan and other chitosan derivatives.Chitosan quaternary ammonium salt
It after being dissolved in water, ionizes, substantial amounts of level Four ammonium cation is contained in solution.Ammonium cation has one to bacterium, fungi, virus
Determine fragmentation effect.
Secondly polyhexamethylene guanide has broad-spectrum；Effective concentration is low；Work fast；Property is stablized；It is soluble easily in water
Excellent performance；It can use at normal temperatures；It is long-term antibacterial, without side-effects；Polyhexamethylene guanide is polyguanidine family macromolecule polymer,
Ionization can be generated in aqueous solution, its hydrophilic base section contains strong electropositive, and absorption is usually in electronegative all kinds of thin
Bacterium, virus into cell membrane, inhibit the synthesis of film lactones plastid, cause thalline apoptosis, reach optimal bactericidal effect.
Chitosan quaternary ammonium salt, polyhexamethylene guanide generate and form cation, and bacterium, fungi and virus can be carried out
It kills and isolates.
Since polyhexamethylene guanide has certain toxicity, when in use, it is necessary to control its dosage, it is preferable that shell gathers
The content of sugared quaternary ammonium salt（Weight）For 4 times or more of polyhexamethylene guanide content；And polyhexamethylene guanide content is no more than 2%.
Alum primarily serves the effect of gel.Alum has antibacterial action, astriction etc., can be used as Chinese medicine, and the traditional Chinese medical science thinks
The effect of alum has removing toxic substances desinsection, and eliminating dampness is antipruritic, antidiarrheal of stopping blooding, heat-clearing and phlegm-dissolving.Research in recent years confirms that alum also has
The effects that antibacterial, anti-Trichomonas vaginalis.Medical alum treats hyperlipidemia, duodenal ulcer, hemoptysis of pulmonary tuberculosis etc. in some
Disease.
Antibacterial action alum has inhibitory action to a variety of Grain-negatives, positive cocci and bacillus；Have to common pyogenic baeceria
Stronger bacteriostasis experiments show：Alum has inhibitory action to staphylococcus aureus, proteus（Test tube method）To large intestine
Bacillus, Pseudomonas aeruginosa, bacillus anthracis, Freund and shigella, typhoid bacillus and paratyphoid A bacillus, proteus and Portugal
Grape coccus etc. has inhibitory action（Paper dish, flat band method）；Viridans streptococci, hemolytic streptococcus, pneumococcus, corynebacterium diphtheriae are made
With most by force, take second place to ox type Brucella, Bordetella pertussis, meningococcus effect, to Bacillus influenzae without effect（Paper disk method）
High concentration alum steep is to human-like（H37RV）And bacillus tuberculosis bovis also has inhibitory action clinically with 0.75% alumen suspension pair
The charrin's disease for controlling burn wound is effective.
Convergence, prevent prolapse effect；Experiment proves：It is very big that there is alum water very strong astriction alum to take irritation orally, therefore
More external applications, can hidroschesis；Also leukorrhea and ulcer can be treated（Concentration is 1%~5%）.
Alum Injection, alum steep and sulfuric acid molten aluminum have the apparent inhibitory action concentration to be more than in isolated rat rectum
When 4%~6%, protein coagulation denaturation can occur, rectum is made to lose wriggling function；After 8% alum steep is injected in around rectum, it can make
Serous coat and smooth muscle coagulation necrosis then form aseptic and are adhered, so that each layer of rectum and rectum are fixed with surrounding tissue,
Rectum, which no longer slips, has report to think, local also to be had certain effect to animal uterus prolapsus with 4% alum solution.
Glycerine, i.e. glycerine is colourless sweet clear and bright thick liquid, odorless；There is warm sweet taste.Glycerine can be in draw air
Moisture content to skin moisture-keeping, the moisture content in skin can also be lockked, it not allowed to be lost in.There is moisturizing.To the skin of baby
Skin can play moisturizing, moist effect.
The effect of star anise oil and effect：1. octagonal main component is fennel oil, its energy stimulating gastrointestinal neural blood vessel promotes
Digestive juice secretion increases gastrointestinal peristalsis, there is the effect of stomach invigorating, promoting the circulation of qi, helps to alleviate spasm, mitigates pain；2. anethene energy
Promote bone marrow cell ripe and be released into peripheral blood, there is apparent increasing leukocyte, it is thin mainly to raise neutral grain
Born of the same parents, available for leukopenia.Illiciumverum has the effect of warming yang for dispelling cold, regulating qi-flowing for relieving pain.Octagonal warm-natured, acrid-sweet flavor, has Wen Yang
Cold dispelling, regulating qi-flowing for relieving pain, the function of warming middle-JIAO and strengthening the spleen；It trembles with fear crymodynia, cold hernia stomachache, abdomen in pain, abdomen available for treatment nausea and vomiting, gastral cavilty
The illnesss such as swollen and decline of kidney-YANG, impotence, constipation, pain in the back.Fennel oil has stimulating gastrointestinal blood vessel, the sanguimotor work of enhancing
With.
Allantoin：Alias Allantoin, Allantoin, Allantion, Allantoin are a kind of second
Interior ureide derivative.A kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, in water crystallization for single prism or
Colorless crystalline powder.Hot water, hot alcohol and diluted sodium hydroxide solution can be dissolved in.The water and alcohol of room temperature are slightly soluble in, is insoluble in ether
With the organic solvents such as chloroform；Its saturated aqueous solution (concentration 0.6%) is in subacidity；PH is 5.5.In the water that pH value is 4-9
Stablize in solution.Also stablize in nonaqueous solvents and dry air；Decomposable asymmetric choice net under boiling and be exposed to sunlight in strong alkali solution.
Weakly acidic condition is improved for Porcine HGF.
Allantoin, which has, promotes cell growth, accelerates the physiological functions such as wound healing, cutin-softening albumen, is skin trauma
Good consolidant and antiulcer agents.It can be used as alleviating and treat xerodermia, scaling skin illness, skin ulcer, disappear
Change road ulcer and inflammation, have good therapeutic effect to osteomyelitis, diabetes, hepatic sclerosis, acne.
Since allantoin is a kind of amphoteric compound, can combine many kinds of substance formed double salt, have be protected from light, sterilization and anticorrosion,
Analgesic, antioxidation can make skin keep moisture content, moisten and soft, be the additive of the cosmetics such as cosmetology, extensively
General adding for freckle cream, anti-acne toner, shampoo, perfumed soap, toothpaste, shaving lotion, conditioner, astringent, anti-sweat deodorization lotion etc.
Add agent.Addition allantoin cosmetics have the effects that protective tissue, it is hydrophilic, absorb water and prevent moisture from distributing；Add allantoin
Hair-cream, hair cream, shampoo, have protective effect to hair, can make hair not bifurcated, constantly hair；Add lipstick, the face of allantoin
Skin, lip can be made soft for frost and high resilience, and has beautiful gloss.Allantoin promotion tissue growth, cell metabolism,
Cutin-softening layer albumen.
Co-Q10 is a kind of fat-soluble antioxidant, and the nutrition of energy human activin cell and cellular energy has and improves people
Body immunity, enhancing is anti-oxidant, slow down aging and enhances the functions such as human activity, is medically widely used in cardiovascular system disease
Disease uses it for nutrient and healthcare products and food additives extensively both at home and abroad.Co-Q10（Coenzyme Q10）Also known as ubiquinone
（Ubiquinone, abridge UQ）, it is a kind of fat-soluble quinones for being present in nature, structure is given birth to vitamin K, dimension
Plain E is similar to plastoquinone.Human body participate in into the cell energy manufacture and activation, be prevention of arterial harden to be formed it is most effective
Anti-oxidant composition.Ubiquinone is present in most eukaryocytes, especially mitochondria.It is one of respiratory chain component；Its online grain
Content on internal film is significantly larger than the content of respiratory chain other components, and the fat-soluble stream that it is made to have height on inner membrance
Dynamic property, particularly suitable as a kind of electron transit mediator of flowing.
Co-Q10 is main there are two effect in vivo, first, being converted into the process of energy in mitochondria in nutriment
In play an important role, second is that there is apparent lipoid peroxidization resistant.It is the energy conversion agent in cell mitochondrial, it is logical
It crosses transfer and transfers electronics and participate in " tricarboxylic acid cycle " generation ATP（Atriphos）, i.e., energy factors are for cell metabolism use.
Co-Q10 is effective antioxidant and free radical scavenger, it embeds online grain as the component of mitochondrial respiratory chain
In internal membrane lipid bimolecular, become alcohol of formula after 2 electronics received from Mitochondria complex I or complex II, then by electronics
Pass to complex III.Internal Co-Q10 becomes alcohol of formula by a large amount of consumption, it is both effective antioxidant, while is also fortune
Dynamic electron carrier, hydrogen atom is given to lipid peroxidation free radical by it from its hydroxyl, thus reduces the lipid of mitochondrial inner membrane
Peroxide reactions.Generate in the process with the general semiquinone of the out-of-proportion free radical of the alcohol of formula of Co-Q10 and Co-Q10,
Or react with oxygen and to form superoxides, the general semiquinone of free radical turns under the action of superoxide dismutase and catalase
It transports free radical and realizes detoxication, the respiratory chain that so moves in circles is constantly regenerating into alcohol of formula by Co-Q10, has recovered the anti-of it
Anti-oxidant active acts on.
Ceramide is also known as sphingolipid, is a kind of lipid for being present in skin, in epidermal keratinocytes layer formation process
It plays an important role.When drying, furfur, cracking phenomena occurs in skin, when barrier function is substantially reduced, skin supplement is neural
Amide can recover rapidly moisturizing and barrier function.
Cause have dry skin main cause be in horny layer of epidermis ceramide content reduce, ceramide content height with
Skin dryness is directly related.Adhesion strength between keratinocyte can be remarkably reinforced using ceramide, improve dry skin journey
Degree reduces desquamation of skin phenomenon.Ceramide has hydrone ability of associating by force very much, it in cuticula by forming netted knot
Structure maintains moisture of skin.Therefore, ceramide, which has, keeps moisture of skin effect.It can be made using ceramide in horny layer of epidermis
Ceramide content increases, and can improve the situations such as dry skin, furfur, coarse；Ceramide can increase horny layer of epidermis simultaneously
Thickness improves skin moisture holding capacity, reduces wrinkle, enhances skin elasticity, delay skin aging.
Ceramide is a kind of water-soluble lipid matter, it is close with the structure of matter for forming keratoderma, can be quickly
The water penetrated into skin and cuticula combines, and forms a kind of net structure, locks moisture.
Peppermint oil, can nurse one's health the skin of unclean obstruction, and refrigerant sensation can shrink capilary, releive and itch, send out
It is scorching and burn, also can soft skin, for removing blackhead and oily skin also great effect.
Peppermint oil has inhibitory action to herpes simplex virus, forest virus, mumps virus, to golden yellow Portugal
Grape coccus, staphylococcus albus, alpha streptococcus, beta streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax
Bacillus, corynebacterium diphtheriae, typhoid bacillus, Pseudomonas aeruginosa, Escherichia coli etc. have bacteriostasis；Water-soluble peppermint oil can stimulate neural end
The cold receptor of the tip and generate creeping chill, and reflectivity cause the variation of deep tissue blood vessel and play anti-inflammatory, analgesic, antipruritic
Effect.
In the technical program, chitosan quaternary ammonium salt, polyhexamethylene guanide mainly play sterilization, antibacterial, hemostasis, repair wound
Effect;Ceramide has antianaphylactic effect;Allantoin has hydrophilic and lipophilic drugs apparent transdermal help to ooze and promote
The effect increased into cell;Co-Q10 plays the role of oxidation resistant;Star anise oil plays analgesic, antipruritic, antianaphylactic；Glycerine
It is mainly used for moisturizing, lubrication and gel conditioning agent；Peppermint oil mainly plays antalgesic-antipruritic；Bright rock plays antibacterial and convergent work
With.
A kind of preparation method of medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Preferably, medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanide 0.15 ~ 0.2%
Bright rock 0.18 ~ 0.21%
Glycerine 14 ~ 16%
Star anise oil 0.09 ~ 0.11%
Allantoin 0.25 ~ 0.35%
Co-Q10 0.4 ~ 0.55%
Ceramide 0.18 ~ 0.21%
Peppermint 0.4 ~ 0.6%
Aloin 0.8 ~ 1%
Purify water surplus.
Aloin can help to discharge internal dirt, purification blood, softening blood vessel, reduce blood pressure and blood viscosity, promote blood
Liquid cycles；Mixture of the active ingredient based on barbaloin is dicotyledon aloe extract.Bactericidal effect, anti-inflammatory effect,
Beautification function is moistened, the effect of letting out under stomach invigorating, cardiac stimulant promoting blood circulation effect, is immunized and palingenesis, immune and antitumor action, removing toxic substances are made
With, anti-aging effects, analgesia, sedation, anti-sunlight function.The polysaccharide and multivitamin contained in aloe has human skin good
Nutrition well is moistened, whitening effect.Aloe barbadensis Miller is the Fresh leaf of aloe of the direct beauty of optimum, i.e. aloe barbadensis Miller, it has
Make skin contraction, softness, moisturizing, anti-inflammatory, the performance of bleaching.Hardening, angling, the effect for improving scar are also released, not only
It can prevent small wrinkle, pouch, cutis laxa, moreover it is possible to skin wet, tender and lovely is kept, at the same time it can also treat scytitis, to powder
Thorn, freckle, acne and scald, knife wound, insect bite etc. also have the effect of fine.It is similarly effective to hair, hair can be kept
Moisten smooth, pre-Anti-hair loss.
Hemorrhoid cause skin to be subject to wound, sometimes with bleeding and inflammation；Increase a certain amount of aloe in dressings
Element can play certain haemostatic effect and antibacterial, anti-inflammatory；By clinical test, do not conflict with other drugs ingredient.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
It is further preferred that a kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanide 0.15 ~ 0.2%
Bright rock 0.18 ~ 0.21%
Glycerine 14 ~ 16%
Star anise oil 0.09 ~ 0.11%
Allantoin 0.25 ~ 0.35%
Co-Q10 0.4 ~ 0.55%
Ceramide 0.18 ~ 0.21%
Peppermint 0.4 ~ 0.6%
Aloin 0.8 ~ 1%
Hydrogen peroxide 1 ~ 2%
Purify water surplus.
Hydrogen peroxide has preferable oxidation effectiveness, using low concentration（Especially weight ratio is less than 3%）Hydrogen peroxide and skin
Wound, fester or dirt when meeting, decompose generation oxygen immediately.This oxygen atom for being not yet combined into oxygen molecule has very strong
Oxidability, when being contacted with bacterium, microorganism can be destroyed, kill bacterium.An aerobic environment can be provided simultaneously, is killed
The collagen of anaerobic bacteria and aid in skin is formed.Here the content of hydrogen peroxide refers to：Weight of the hydrogen peroxide in entire dressing
Measure content：1%~2%.Here hydrogen peroxide content is the content of pure hydrogen peroxide.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin, hydrogen peroxide；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Beneficial effects of the present invention are：Available for repair and improve internal piles, external piles, mixed hemorrhoid and anal fissure, after anal fistula operation
The symptoms such as caused bleeding, pain, rectal tenesmus promote haemorrhoids to reduce, prevent haemorrhoids prolapsus and mitigate hemorrhoid mucous membrane congestion and edema
Etc. symptoms, the also nursing available for anal disease treatments such as hemorrhoid.
Specific embodiment
The present invention is described further below.
Embodiment 1：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 8%
Polyhexamethylene guanide 0.1%
Bright rock 0.15%
Glycerine 18%
Star anise oil 0.12%
Allantoin 0.4%
Co-Q10 0.3%
Ceramide 0.15%
Peppermint 0.3%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 1：
Huang, man, 31 years old, with internal piles, surface swelling and pain were often had blood in stool；Smear the medical hemorrhoid Biological water of the present embodiment
Gel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after a week.It is cured after 6 weeks.
Embodiment 2：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 12%
Polyhexamethylene guanide 0.2%
Bright rock 0.23%
Glycerine 12%
Star anise oil 0.08%
Allantoin 0.2%
Co-Q10 0.6%
Ceramide 0.25%
Peppermint 0.65%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 2
Zhang, female, 35 years old, painless, intermittent, blood after an action of the bowels, just when bleed or toilet paper on band blood；Apply the present embodiment
Medical hemorrhoid biological hydrogel functional dressings 3 weeks, hemostasis.
Embodiment 3：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanide 0.2%
Bright rock 0.18%
Glycerine 16%
Star anise oil 0.09%
Allantoin 0.35%
Co-Q10 0.4%
Ceramide 0.21%
Peppermint 0.4%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 3
Mr. Lin, man, 31 years old, with external piles, pain, stool band blood；Smear the medical hemorrhoid biological hydrogel of the present embodiment
Functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 2 weeks.It is cured after 8 weeks.
Embodiment 4：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanide 0.15%
Bright rock 0.21%
Glycerine 14%
Star anise oil 0.11%
Allantoin 0.25%
Co-Q10 0.55%
Ceramide 0.18%
Peppermint 0.6%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 4：
Lee, man, 45 months, with mixed hemorrhoid, swelling and pain had inflammation, often have blood in stool；Smear the medical hemorrhoid of the present embodiment
Biological hydrogel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 2 weeks.It is cured after 7 weeks.Embodiment 5：A kind of medical hemorrhoid life
Object hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanide 0.2%
Bright rock 0.2%
Glycerine 15%
Star anise oil 0.1%
Allantoin 0.3%
Co-Q10 0.5%
Ceramide 0.2%
Peppermint 0.5%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 5
Zhang, man, 48 years old, anal operation of postop., anus pain was often had blood in stool；Use the medical hemorrhoid biology of the present embodiment
3 times a day, after a week, pain gradually disappears or weakens hydrogel functional dressings, oligemia；After 4 weeks, basic without pain, just
Blood；It is cured after 6 weeks.
Embodiment 6：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9.8%
Polyhexamethylene guanide 0.18%
Bright rock 0.19%
Glycerine 15.5%
Star anise oil 0.1%
Allantoin 0.31%
Co-Q10 0.49%
Ceramide 0.19%
Peppermint 0.48%
Aloin 0.9%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 6
Mr. Lin, man, 42 years old, with internal piles, surface swelling and pain were often had blood in stool；Smear the medical hemorrhoid Biological water of the present embodiment
Gel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 3 days.It is cured after 4 weeks.
Embodiment 7：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanide 0.15%
Bright rock 0.21%
Glycerine 16%
Star anise oil 0.09%
Allantoin 0.25%
Co-Q10 0.55%
Ceramide 0.21%
Peppermint 0.4%
Aloin 0.8%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 7
Field, female, 61 years old, anal operation of postop., rectal tenesmus were had blood in stool often；Use the medical hemorrhoid biology of the present embodiment
3 times a day, after 4 days, falling inflation disappears hydrogel functional dressings；After a week, nothing is had blood in stool.
Embodiment 8：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanide 0.2%
Bright rock 0.18%
Glycerine 14%
Star anise oil 0.11%
Allantoin 0.35%
Co-Q10 0.4%
Ceramide 0.18%
Peppermint 0.6%
Aloin 1%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Case 8：Zhang, female, 52 years old, with external piles, pain, stool band blood；Smear the medical hemorrhoid biology of the present embodiment
Hydrogel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 2 weeks.It is cured after 8 weeks.
Embodiment 9：
A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanide 0.15%
Bright rock 0.18%
Glycerine 16%
Star anise oil 0.11%
Allantoin 0.35%
Co-Q10 0.4%
Ceramide 0.18%
Peppermint 0.4%
Aloin 1%
Hydrogen peroxide 2%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin, hydrogen peroxide；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Since 100% hydrogen peroxide of content is difficult to obtain, the hydrogen peroxide for the quality such as the hydrogen peroxide in step 1 uses, other are dense
Hydrogen peroxide is spent to substitute；That is step 1 when with hydrogen peroxide is taken, can match somebody with somebody other concentration hydrogen peroxide for taking equivalent, such as contain with taking
Measure 30% hydrogen peroxide of hydrogen peroxide（Quality containing hydrogen peroxide is equal）；Step 2 replaces with：Weigh the purified water of surplus.
Case 9：Certain is closed, man 33 years old, there is mixed hemorrhoid, and swelling and pain have inflammation, often have blood in stool；Smear the medical hemorrhoid of the present embodiment
Sore biological hydrogel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 3 weeks.It is cured after 5 weeks.
Embodiment 10：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanide 0.2%
Bright rock 0.21%
Glycerine 14%
Star anise oil 0.09%
Allantoin 0.25%
Co-Q10 0.55%
Ceramide 0.21%
Peppermint 0.6%
Aloin 0.8%
Hydrogen peroxide 1%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin, hydrogen peroxide；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Since 100% hydrogen peroxide of content is difficult to obtain, the hydrogen peroxide for the quality such as the hydrogen peroxide in step 1 uses, other are dense
Hydrogen peroxide is spent to substitute；That is step 1 when with hydrogen peroxide is taken, can match somebody with somebody other concentration hydrogen peroxide for taking equivalent, such as contain with taking
Measure 30% hydrogen peroxide of hydrogen peroxide（Quality containing hydrogen peroxide is equal）；Step 2 replaces with：Weigh the purified water of surplus.
Case 10：Zhang, man, 51 years old, anal operation of postop., anus pain was often had blood in stool；Use the medical hemorrhoid of the present embodiment
3 times a day, after 4 days, pain gradually disappears or weakens sore biological hydrogel functional dressings, oligemia；After 2 weeks, substantially without pain
Bitterly, have blood in stool；It is cured after 4 weeks.
Embodiment 11：A kind of medical hemorrhoid biological hydrogel functional dressings, by following raw material（Weight ratio）Composition：
Chitosan quaternary ammonium salt 10.5%
Polyhexamethylene guanide 0.19%
Bright rock 0.2%
Glycerine 15%
Star anise oil 0.1%
Allantoin 0.3%
Co-Q10 0.5%
Ceramide 0.2%
Peppermint 0.5%
Aloin 1%
Hydrogen peroxide 1.5%
Purify water surplus.
A kind of preparation method of above-mentioned medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin,
Co-Q10, ceramide, peppermint oil, aloin, hydrogen peroxide；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Since 100% hydrogen peroxide of content is difficult to obtain, the hydrogen peroxide for the quality such as the hydrogen peroxide in step 1 uses, other are dense
Hydrogen peroxide is spent to substitute；That is step 1 when with hydrogen peroxide is taken, can match somebody with somebody other concentration hydrogen peroxide for taking equivalent, such as contain with taking
Measure 30% hydrogen peroxide of hydrogen peroxide（Quality containing hydrogen peroxide is equal）；Step 2 replaces with：Weigh the purified water of surplus.
Case 11：Zhang, man, 41 years old, with mixed hemorrhoid, swelling and pain had inflammation, often have blood in stool；Smear the medical of the present embodiment
Hemorrhoid biological hydrogel functional dressings are 3 times a day；Swelling and pain relieving, hemostasis after 1 week.It is cured after 3 weeks.
It the above is only the preferred embodiment of the application, equivalent technical solutions on this basis still fall within application protection model
It encloses.
Claims (5)
1. medical hemorrhoid biological hydrogel functional dressings, it is characterised in that：It comprises the following raw materials by weight percent：
The preparation method of the medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh chitosan quaternary ammonium salt, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin, the coenzyme of formula ratio
Q10, ceramide, peppermint oil；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
2. medical hemorrhoid biological hydrogel functional dressings according to claim 1, it is characterised in that：By following weight percent
The raw material composition of ratio：
3. medical hemorrhoid biological hydrogel functional dressings according to claim 1, it is characterised in that：By following weight percent
The raw material composition of ratio：
4. medical hemorrhoid biological hydrogel functional dressings, it is characterised in that：It comprises the following raw materials by weight percent：
The preparation method of the medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh chitosan quaternary ammonium salt, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin, the coenzyme of formula ratio
Q10, ceramide, peppermint oil, aloin；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
5. medical hemorrhoid biological hydrogel functional dressings, it is characterised in that：It comprises the following raw materials by weight percent：
The preparation method of the medical hemorrhoid biological hydrogel functional dressings, including：
Step 1: weigh chitosan quaternary ammonium salt, polyhexamethylene guanide, alum, glycerine, star anise oil, allantoin, the coenzyme of formula ratio
Q10, ceramide, peppermint oil, aloin, hydrogen peroxide；
Step 2: weigh the purified water of formula ratio；
The formula of step 1 is poured into purified water and mixed by step 3 successively.
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| CN107754011A (en) * | 2017-11-13 | 2018-03-06 | 广西达庆生物科技股份有限公司 | A kind of liquid dressing for treating hemorrhoid and preparation method thereof |
| CN109568678B (en) * | 2019-01-04 | 2021-11-12 | 李海青 | Perianal abscess postoperative drainage strip and preparation method thereof |
| CN114533859B (en) * | 2022-02-23 | 2023-04-25 | 宁波项谨记百货有限公司 | Traditional Chinese medicine ointment for treating hemorrhoids and preparation method thereof |
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| CN103285028A (en) * | 2013-05-14 | 2013-09-11 | 陈美儿 | Composite antibacterial agent of chitosan and organosilicone quaternary ammonium salt and preparation method of composite antibacterial agent |
| CN104027448A (en) * | 2014-04-16 | 2014-09-10 | 广西信业生物技术有限公司 | Chitosan gel and preparation method thereof |
| CN104337756A (en) * | 2013-07-25 | 2015-02-11 | 江苏新智源医学科技有限公司 | Chitosan gynecological gel and preparation method thereof |
| CN104434544A (en) * | 2013-09-16 | 2015-03-25 | 詹尼克公司 | Gel mask using lace sheet |
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| WO2009046116A1 (en) * | 2007-10-01 | 2009-04-09 | Dennis Gross | Skin care products containing multiple enhancers |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103285028A (en) * | 2013-05-14 | 2013-09-11 | 陈美儿 | Composite antibacterial agent of chitosan and organosilicone quaternary ammonium salt and preparation method of composite antibacterial agent |
| CN104337756A (en) * | 2013-07-25 | 2015-02-11 | 江苏新智源医学科技有限公司 | Chitosan gynecological gel and preparation method thereof |
| CN104434544A (en) * | 2013-09-16 | 2015-03-25 | 詹尼克公司 | Gel mask using lace sheet |
| CN104027448A (en) * | 2014-04-16 | 2014-09-10 | 广西信业生物技术有限公司 | Chitosan gel and preparation method thereof |
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Address after: 523000, Guangdong City, Dongguan province Sanyuanli community finance business building, two floor, No. 205-208, Dongguan City Da Qing Medical Equipment Co., Ltd. Patentee after: DONGGUAN DAQING MEDICAL DEVICES Co.,Ltd. Patentee after: GUANGXI DAQING BIOLOGICAL SCIENCE & TECHNOLOGY Co.,Ltd. Patentee after: GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co.,Ltd. Address before: 523000, Guangdong City, Dongguan province Sanyuanli community finance business building, two floor, No. 205-208, Dongguan City Da Qing Medical Equipment Co., Ltd. Patentee before: DONGGUAN DAQING MEDICAL DEVICES Co.,Ltd. Patentee before: GUANGXI DAQING BIOTECHNOLOGY Co.,Ltd. Patentee before: GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co.,Ltd. |
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