CN105169150A - Traditional Chinese medicine composition for treating acute eczema - Google Patents

Abstract

A traditional Chinese medicine composition for treating acute eczema is prepared from leaves of purpleflower hollies, lithospermum, burdock, radices sileris, gentiana macrophylla, feather cockscomb seeds, notopterygium, rhizoma sparganii, cordate houttuynia, semen plantaginis, andrographis paniculata, fried jasmines, lalang grass rhizome, natural indigo, gentian, dianthus superbus, coptis chinensis, garden burnet, caulis polygoni multiflori, radix ophiopogonis, agastache rugosus, folium mori, tribulus terrestris, semen coicis, dandelions, chrysanthemums, folium isatidis, radix ampelopsis, bighead atractylodes rhizome, caulis spatholobi and angelica sinensis. The traditional Chinese medicine composition is easy and convenient to prepare, wide in medicine source, low in cost and capable of achieving the remarkable effects in the aspects of relieving the illness condition of a patient, improving efficiency, shortening the treating time, preventing relapse, maintaining stability of the illness condition, improving the living quality of the patient, being free of damage to the body of the patient, being free of toxic and side effects, being free of medicine resistance and the like, and thus defects brought by western medicine are overcome.

Description

A kind of Chinese medicine composition being used for the treatment of acute eczema

Technical field

The invention belongs to medical art, relate to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition being used for the treatment of acute eczema.

Background technology

Eczema is a kind of anaphylactic disease, its reason may with sensitinogen or allergy relevant with allergic constitution, be a kind of common diseases associated with inflammation of department of dermatologry, clinical many with erythra form, be easy to ooze out, the course of disease is delayed, easy recurrence is feature, and violent pruritus is its cardinal symptom.Caused by multiple internal and external factor, its exopathogenic factor contacts with weather, the articles for daily use, diet etc. is relevant, endogenous cause of ill with nervous, tired, have a sleepless night, endocrine, digestive functional disturbance, dysbolismus etc. are relevant, in recent years, because air pollution, social pressure increase, the factors such as industrialization degree expands, the change of dietary structure, the sickness rate of eczema has the trend raised year by year, eczema has been an important public health problem in the world now, has a strong impact on patient's physically and mentally healthy and quality of life.

Eczema is divided into acute eczema according to the course of disease, subacute eczema and chronic eczema, wherein, acute eczema accounts for 15% of Dermatology Outpatient Department amount, it is by multiple, the inflammatory dermatoses of the epidermis that other factor causes and high dermis, there is multiformity erythra and ooze out tendency, accompany violent pruritus, easy recurrent exerbation, normal and allergy has certain relation, severe patient general the whole body and acute pruritus can be formed again rotten to the corn then infection and all cause very large misery to patient body and psychology because scratching, if treatment can change subacute and chronic eczema not in time, course of disease protracted course of disease, very itch unbearably.Acute eczema is in early days or acute phase, and clinical symptoms is erythema in blocks and pimple, or the vesicle that naked eyes have no, and occurs large stretch of sepage and erosion time serious.

The etiology and pathology of acute eczema

A kind of delayed of acute eczema pathogeny mainly caused by inside and outside motivating factor interaction can allergy.The allergic constitution of patient is the important pathogenic factors of primary disease, relevant with heredity, can with age, environment and changing.Endogenous cause of ill is as chronic digestive system disease, psychentonia, insomnia, overtired, emotion changes, endocrine disturbance, infection, dysbolism etc.Exopathogenic factor such as living environment, climate change, food etc. all can affect the generation of eczema.Environmental stimuli as daylight, cold, drying, sweltering heat, hot water is scalded and various animal skin, plant, cosmetics, soap, staple fibre etc. all can bring out.

The clinical manifestation of acute eczema

Morbidity is anxious, and can occur in any position of whole body, but often more easily see head, extremity bend the positions such as side, pudendum, brothers' back of the body.Often be symmetric, be generally and be confined to some position, and whole body universal eczema be very rare.Often often scratch because of violent pruritus, aggravate disease.Show as constitutional and pleomorphism erythra.Erythema of being everlasting basis there is syringe needle arrive pimple, the papulovesicle of foxtail millet grain size, have phlysis time serious, permelting answer print, indefinite border Chu.In the periphery of infringement, above-mentioned pleomorphism erythra is sparse gradually.Pruritus is heavier, and Chang Yin scratches and makes erythra form rotten to the corn face, and has serosity to ooze out and form a scab.In disease, the various erythra such as erythema, pimple, vesicle, pustule, erosion, incrustation can occur in proper order, but often have 2-3 kind erythra simultaneously and deposit or at certain one-phase based on certain type erythra.As formed pustule, pus and pus crusts with secondary infection, corresponding lymph node can enlargement.Can with General Symptomies such as heatings when infecting serious.Subjective symptoms has violent pruritus and burning sensation, can paroxysm increase the weight of, especially with aggravation in night, and impact sleep and work.

The western medical treatment of acute eczema

Eczematosis because of complexity, treatment still easy recurrent exerbation after taking a turn for the better, difficult radical cure.Doctor trained in Western medicine mainly comprises following Therapeutic Method:

Constitutional treatment

Antihistamine drug: common medicine has chlorphenamine (chlorphenamine); Cyproheptadine; Diphenhydramine; Also the medicine without the calm side effect of maincenter can be selected, as terfenadine; Cetirizine.Can two kinds of medicine alternate application or use in conjunction.

Nonspecific desensitization is treated: available 10% calcium gluconate 10ml or 10% sodium thiosulfate 10ml intravenous injection; Or 0.25% procaine vitaminize intravenous injection.

Glucocorticoid: generally do not advocate application, remarkable and general originator can consider that short-term is taken, as prednisone to acute phase inflammatory.

Antibiotic: to bacteriological infection, heating, lymphadenectasis person, can select as erythromycin for oral administration, ciprofloxacin or intramuscular injection penicillin etc.

Topical therapeutic

Flushing, pimple or minority phlycten is only had and without sepage at the disease initial stage, control and should relax antiinflammatory, avoid stimulating, soak can be selected or there is the lotion of itching-relieving action, conventional 2% ~ 3% boric acid water soak, Calamine Lotion or 2% Camphor tree alcohol (Borneolum Syntheticum) 5% Alumen Calamine Lotion etc.

Obvious person is oozed out in vesicle erosion, should restrain, antiinflammatory, to promote that epidermis recovers, anticorrosion convergence medicinal liquid can be selected to make soak or evaporation net for catching birds or fish bag, dust head as Compound Zinc copper solution, 2% ~ 3% boric acid water, 0.5% lead acetate or Burow's Solution.

Property eczema latter stage---the exfoliation phase, as dealt with improperly, easily make the course of disease delay recurrence or transfer to chronic.Current period Therapeutic Principle should protect skin lesion, avoids environmental stimuli, promotes that cutin is newborn, eliminates remaining inflammation, can apply refrigerant ointment, Rhizoma Coptidis ointment or general Emulsion.

Find in clinical treatment, doctor trained in Western medicine curative effect is undesirable, and relapse rate is high, and toxic and side effects is comparatively large, expensive, and extensive patients is not easy to accept.

Summary of the invention

The present invention is directed to weak point of the prior art, a kind of Chinese medicine composition being used for the treatment of acute eczema be provided, this Chinese medicine composition preparation easy, cost is low, evident in efficacy, have no side effect.

Above-mentioned purpose of the present invention is realized by following technical proposals:

Be used for the treatment of a Chinese medicine composition for acute eczema, the crude drug of described Chinese medicine composition is made up of Ilex purpurea Hassk.[I.chinensis Sims, Radix Arnebiae (Radix Lithospermi), Fructus Arctii, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Semen Celosiae, Rhizoma Et Radix Notopterygii, Rhizoma Sparganii, Herba Houttuyniae, Semen Plantaginis, Herba Andrographis, Fructus Gardeniae (parched), Rhizoma Imperatae, Indigo Naturalis, Radix Gentianae, Herba Dianthi, Rhizoma Coptidis, Radix Sanguisorbae, Caulis Polygoni Multiflori, Radix Ophiopogonis, Herba Pogostemonis, Folium Mori, Fructus Tribuli, Semen Coicis, Herba Taraxaci, Flos Chrysanthemi, Folium Isatidis, Radix Ampelopsis, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Radix Angelicae Sinensis.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 3-6 part, Radix Arnebiae (Radix Lithospermi) 8-13 part, Fructus Arctii 3-5 part, Radix Saposhnikoviae 11-15 part, Radix Gentianae Macrophyllae 5-10 part, Semen Celosiae 2-5 part, Rhizoma Et Radix Notopterygii 4-9 part, Rhizoma Sparganii 12-20 part, Herba Houttuyniae 10-16 part, Semen Plantaginis 3-8 part, Herba Andrographis 5-12 part, Fructus Gardeniae (parched) 12-17 part, Rhizoma Imperatae 7-12 part, Indigo Naturalis 4-9 part, Radix Gentianae 15-20 part, Herba Dianthi 10-15 part, Rhizoma Coptidis 8-12 part, Radix Sanguisorbae 2-5 part, Caulis Polygoni Multiflori 3-7 part, Radix Ophiopogonis 11-14 part, Herba Pogostemonis 9-15 part, Folium Mori 3-6 part, Fructus Tribuli 8-13 part, Semen Coicis 3-5 part, Herba Taraxaci 1-3 part, Flos Chrysanthemi 5-10 part, Folium Isatidis 5-10 part, Radix Ampelopsis 13-16 part, Rhizoma Atractylodis Macrocephalae 3-10 part, Caulis Spatholobi 8-13 part, Radix Angelicae Sinensis 3-5 part.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 5 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Sparganii 12 parts, Herba Houttuyniae 16 parts, Semen Plantaginis 3 parts, Herba Andrographis 12 parts, Fructus Gardeniae (parched) 12 parts, Rhizoma Imperatae 10 parts, Indigo Naturalis 9 parts, Radix Gentianae 15 parts, Herba Dianthi 15 parts, Rhizoma Coptidis 8 parts, Radix Sanguisorbae 5 parts, Caulis Polygoni Multiflori 3 parts, Radix Ophiopogonis 14 parts, Herba Pogostemonis 9 parts, 6 parts, Folium Mori, Fructus Tribuli 8 parts, Semen Coicis 5 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 5 parts, Radix Ampelopsis 16 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Caulis Spatholobi 8 parts, Radix Angelicae Sinensis 5 parts.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 13 parts, Radix Gentianae Macrophyllae 6 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Sparganii 20 parts, Herba Houttuyniae 10 parts, Semen Plantaginis 8 parts, Herba Andrographis 5 parts, Fructus Gardeniae (parched) 17 parts, Rhizoma Imperatae 12 parts, Indigo Naturalis 4 parts, Radix Gentianae 20 parts, Herba Dianthi 10 parts, Rhizoma Coptidis 12 parts, Radix Sanguisorbae 2 parts, Caulis Polygoni Multiflori 7 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 15 parts, 3 parts, Folium Mori, Fructus Tribuli 13 parts, Semen Coicis 3 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 5 parts, Folium Isatidis 10 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Caulis Spatholobi 13 parts, Radix Angelicae Sinensis 3 parts.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 5 parts, Radix Arnebiae (Radix Lithospermi) 12 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 9 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Sparganii 13 parts, Herba Houttuyniae 11 parts, Semen Plantaginis 4 parts, Herba Andrographis 6 parts, Fructus Gardeniae (parched) 13 parts, Rhizoma Imperatae 7 parts, Indigo Naturalis 5 parts, Radix Gentianae 18 parts, Herba Dianthi 11 parts, Rhizoma Coptidis 9 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 6 parts, Radix Ophiopogonis 12 parts, Herba Pogostemonis 13 parts, 4 parts, Folium Mori, Fructus Tribuli 9 parts, Semen Coicis 4 parts, Herba Taraxaci 2 parts, Flos Chrysanthemi 6 parts, Folium Isatidis 6 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Caulis Spatholobi 10 parts, Radix Angelicae Sinensis 4 parts.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 11 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 14 parts, Radix Gentianae Macrophyllae 8 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 6 parts, Rhizoma Sparganii 17 parts, Herba Houttuyniae 15 parts, Semen Plantaginis 7 parts, Herba Andrographis 11 parts, Fructus Gardeniae (parched) 16 parts, Rhizoma Imperatae 8 parts, Indigo Naturalis 8 parts, Radix Gentianae 16 parts, Herba Dianthi 14 parts, Rhizoma Coptidis 11 parts, Radix Sanguisorbae 3 parts, Caulis Polygoni Multiflori 5 parts, Radix Ophiopogonis 13 parts, Herba Pogostemonis 14 parts, 5 parts, Folium Mori, Fructus Tribuli 12 parts, Semen Coicis 3 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 9 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Caulis Spatholobi 11 parts, Radix Angelicae Sinensis 3 parts.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 9 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 5 parts, Rhizoma Et Radix Notopterygii 9 parts, Rhizoma Sparganii 15 parts, Herba Houttuyniae 12 parts, Semen Plantaginis 5 parts, Herba Andrographis 9 parts, Fructus Gardeniae (parched) 15 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 7 parts, Radix Gentianae 19 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Caulis Spatholobi 12 parts, Radix Angelicae Sinensis 5 parts.

Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 3 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 2 parts, Rhizoma Et Radix Notopterygii 4 parts, Rhizoma Sparganii 19 parts, Herba Houttuyniae 14 parts, Semen Plantaginis 6 parts, Herba Andrographis 7 parts, Fructus Gardeniae (parched) 14 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 6 parts, Radix Gentianae 17 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Caulis Spatholobi 9 parts, Radix Angelicae Sinensis 5 parts.

Further, be prepared in accordance with the following steps:

(1) get each medical material according to components by weight percent, add the 10-12 water doubly of medical material gross weight, soak after 45-60 minute, decoct 1 time, decocting time 2 hours, after filtration, adds the 12-13 water doubly of medical material gross weight, decoct the 2nd time, decocting time 3 hours, after filtration, add the 14-15 water doubly of medical material gross weight, decoct the 3rd time, decocting time 4 hours, after filtration, merge 3 filtrates, 120 orders filter, at filtrate heating is concentrated into 60 DEG C, relative density is 1.10 ~ 1.13, obtains concentrated solution, for subsequent use;

(2) added water by gained concentrated solution in step (1) and be adjusted to 2000 parts, filter, sterilizing, obtains abrasive cleaner; Or gained concentrated solution in step (1) being continued heating, to be concentrated into 60 DEG C of relative densities be the thick paste of 1.28-1.33, obtains Chinese medical concrete, described Chinese medical concrete is made ointment, specification: 0.2g crude drug/g ointment.

The invention still further relates to the application of a kind of described Chinese medicine composition being used for the treatment of acute eczema in treatment acute eczema medicine.

The Chinese medicine composition being used for the treatment of acute eczema provided by the present invention, it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:

Ilex purpurea Hassk.[I.chinensis Sims: base is former: be the leaf of winter plant Ilicis Purpureae.Chemical analysis: containing protocatechuic acid, protocatechualdehyde, ursolic acid, flavonoid glycoside, triterpenes, saccharide.Pharmacological action: 1, antibacterial action; 2, Experiment on therapy scald effect; 3, on the impact of cardiovascular system; 4. antiinflammatory action; 5. antitumor action; Nature and flavor: bitter; Puckery; Cool.Function cures mainly: heat-clearing and toxic substances removing; Promoting tissue regeneration and ulcer healing; Promoting blood circulation and hemostasis.Main cough due to lung-heat; Laryngopharynx swelling and pain; Dysentery; Diarrhoea; Biliary tract infection; Urinary tract infection; Angina pectoris; Burn and scald; Pyretic toxicity carbuncle; Ulcer of the lower limb; Leprelcosis; Eczema; Chilblain; Chap; Thromboangiitis obliterans; Traumatic hemorrhage.

Radix Arnebiae (Radix Lithospermi) is sweet, salty, cold.GUIXIN, Liver Channel.Function cures mainly: removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.

Fructus Arctii: the effect with dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling, cure mainly cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule not thoroughly, rubella pruritus, sore swollen toxin.Be selected from the dry mature fruit of feverfew Fructus Arctii ArctiumlappaL..

Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.Return bladder, lung, spleen, Liver Channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.For diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness.

Radix Gentianae Macrophyllae, toil, flat.Enter liver, stomach, gallbladder meridian.Function cures mainly: expelling wind and removing dampness, and blood relaxing muscles and tendons, clearing away heat and promoting diuresis.Dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.

Semen Celosiae: bitter in the mouth, cold in nature; Return Liver Channel.To dispel people's heat, clearing away liver-fire, improving acuity of vision and removing nebula.Main conjunctival congestion and swelling pain, nebula of looking unfamiliar film, blurring of vision, hypertension, epistaxis, skin wind heat pruritus, skin ulcer tinea." property of medicine opinion " carries: " the dirty pyretic toxicity dotting punch for the treatment of the liver, red barrier, optic atrohic blindness, nebula are swollen.Main malignant boil scabies scabies, controls the inferior portion's worm dew skin ulcer.”

Rhizoma Et Radix Notopterygii, acrid in the mouth; Bitter; Warm in nature.Loose exterior cold; Wind-damp dispelling; Profit joint; Pain relieving.Main affection of exogenous wind-cold; Have a headache lossless; Edema due to wind pathogen edema; Sore swollen toxin.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.Induce sweat cold expelling, expelling wind and dampness, pain relieving.

Rhizoma Sparganii: acrid in the mouth; Puckery; Cool.Enter liver.Spleen channel.Control lump in the abdomen, gather, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury.Cough due to lung-heat controlled by mongolian medicine, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease, and " precious day " is sick, fracture.

Herba Houttuyniae: latin name houttuyniaeherba, acrid in the mouth, cold nature, enters lung, urinary bladder channel, has heat-clearing and toxic substances removing, removing pus and relieving carbuncle, effect of inducing diuresis for treating stranguria syndrome, and for pneumonopathy vomiting pus, expectorant heat syndrome cough is breathed heavily, toxic-heat and blood stasis, damp-heat gonorrhoea, pyretic toxicity carbuncle sore, and snakeworm wants first-class card.

Semen Plantaginis: clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.

Herba Andrographis: bitter in the mouth, cold in nature, GUIXIN, lung, large intestine, urinary bladder channel, have heat-clearing and toxic substances removing, removing heat from blood, and detumescence, effect of dampness, cures mainly cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, the cards such as venom.

Fructus Gardeniae (parched) is bitter, cold.GUIXIN, lung, tri-jiao channel.Cure mainly pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.

Rhizoma Imperatae, sweet, cold.Return lung, stomach, urinary bladder channel.Function cures mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.

Indigo Naturalis, salty, cold.Return Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.

Radix Gentianae, bitter, cold.Return liver, gallbladder meridian.Be used as medicine part for gentianaceae plant Radix Gentianae, Gentiana manshurica, G. triflora and Yunnan Radix Gentianae, root welding technology.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms." detailed outline ": treat throat pain, wind heat night sweat.Fire is posted in liver and gall mutually, have rush down of no help, therefore the gas of the liver benefiting gallbladder of Radix Gentianae, just with its can eliminating pathogen in the liver gallbladder pathogenic heat also.But in large bitter Great Cold, cross clothes and probably to injure one's stomach the gas of middle hair growth promoting, instead help pathogenic fire, also take Rhizoma Coptidis for a long time instead from the justice of cremate." book on Chinese herbal medicine is newly organized ": Radix Gentianae, its merit, specially in diuretic, disappears wet, and except jaundice, all the other are controlled order, dysentery relieving, detumescent, bring down a fever, and the speech of all popularizations also.But this kind too divides profit, rather consume gas deteriorated blood, water goes and blood also goes, wet disappearing and gas also disappears, from the beginning of water to wet jaundice, have to urgently with it, the water of prolonged illness wets jaundice, with must delay, just cannot not entirely rely on for diuretic god red, disappearing the wet miraculous cure removing illness also.Or meaning Radix Gentianae is controlled damp and hot, the most sharp illness is sick, just damp and hot disease also, so with Radix Gentianae with subcutaneous ulcer of harnessing the Yellow River, have not effect person, how also more? the real incessantly damp and hot one of jaundice also, have not hot and also become jaundice person, can control also by non-Radix Gentianae.Outstanding Radix Gentianae rushes down the heat in wetting, and can not rush down not hot wetting also.

Herba Dianthi: bitter, cold.Enter the heart, kidney, small intestine meridian.Function cures mainly: inducing diuresis for treating stranguria syndrome, and removing blood stasis stimulates the menstrual flow.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, the puckery pain of pouring drop, increase warp.

Rhizoma Coptidis, bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.

Radix Sanguisorbae property of medicine picric acid; Cold; Nontoxic, return liver; Lung; Kidney; Large intestine channel, effect cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.Effect classification hemorrhage; Blood-cooling hemostatic.Cure mainly haematemesis, spitting of blood, epistaxis, hematuria, has blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting." detailed outline ": Radix Sanguisorbae, except part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels heat, controls defecation blood disorder.Hemostasis, get and cut off sheet and fry use, its tip then can promoting the circulation of blood, can not know.Yang Shiying cloud: all skin ulcer pain persons add Radix Sanguisorbae, and the person of itching adds Radix Scutellariae.

Caulis Polygoni Multiflori: sweet in the mouth, property is put down, and GUIXIN, Liver Channel, have nourishing blood to tranquillize the mind, and effect of dispelling wind and removing obstruction in the collateral, cures mainly insomnia and dreamful sleep, blood deficiency general pain, rheumatic arthralgia; The cards such as skin pruritus, Caulis Polygoni Multiflori can be invigorated blood circulation, stimulate the menstrual flow, the detumescence of blood vessel dilating, blood circulation promoting, stimulating milk secretion.

Radix Ophiopogonis, sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Herba Pogostemonis, pungent, tepor.As lung, spleen, stomach warp.Function cures mainly: fast gas, and in, ward off dirty, damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast wrist painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.

Folium Mori: property is sweet, bitter, cold, return lung, Liver Channel; Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving; For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Record in Compendium of Material Medica: Folium Mori " juice decocts Dai Ming, can only quench one's thirst "; " moxibustion is ripe decocts drink, quenches the thirst for tea ".Modern medicine study shows, trace element containing abundant potassium, calcium, ferrum and vitamin C, B1, B2, B3, A, folic acid and the needed by human body such as copper, zinc in Folium Mori, there is blood pressure lowering, blood fat reducing, defying age, increase endurance, reduce lipids contents, reduce cholesterol, suppress the unique effects such as intestinal toxic bacterial reproduction and peroxide generation, have good health-care effect to human body.Containing more folic acid in Folium Mori, every Ke Sangye is approximately containing folic acid 105 μ g, and it can participate in the synthesis of nucleic acid, the effect of anti-various anemia and growth promoting effects can be reached, and can gastric cancer be treated, intestines and stomach obstacle, neural tube defects, the diseases such as malnutrition and skin ulcer rash inflammation are useful to health.Have chromocor compound and the Mulberry glycosides of high level in Folium Mori, chromocor compound effectively can reduce human senility speed slow down aging, and has beautification function; Mulberry glycosides then has refrigerant improving eyesight, the effect of suppressing the hyperactive liver to relieve the wind syndrome.Folium Mori also have hot refreshment effect of dispelling.

Fructus Tribuli, nature and flavor: bitter in the mouth, pungent, property are put down, and have effect of suppressing the hyperactive liver, resolving depression, dispelling pathogenic wind for improving eyesight, the disease such as be used for the treatment of headache, dizzy, distending pain in the chest and hypochondrium, distending pain of the breast, breast close obstructed, amenorrhea, cataract, rubella pruritus, vitiligo, skin ulcer cellulitis, scrofula.

Semen Coicis, sweet in the mouth, light, cold nature.Return spleen, stomach, lung meridian.Energy promoting diuresis to eliminate damp pathogen, damp eliminating eliminating impediment, invigorating the spleen to arrest diarrhea, clearing away heat and discharging pus.Cure mainly dysuria, edema, beriberi, arthralgia chiefly caused by damp pathogen contracture, hygropyrexia from the beginning of and the card such as diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis.

Herba Taraxaci: be feverfew Herba Taraxaci TaraxacummongolicumHand.-Mazz., alkali ground Herba Taraxaci TaraxacumsinicumKitag. or the dry herb belonging to several plants together.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.

Flos Chrysanthemi: sweet, bitter, is slightly cold.Dispelling wind, heat clearing away, improving eyesight, removing toxic substances.Control headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.

Folium Isatidis: bitter in the mouth, cold in nature.Return liver, the heart, stomach, spleen channel.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.For the high hot excessive thirst of calentura; Coma; Macule; Spit blood; Epistaxis; Jaundice; Dysentery; Erysipelas; Sore throat; Aphtha; Mumps.

Radix Ampelopsis: bitter, is slightly cold.GUIXIN, stomach warp.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, expelling pus and promoting granulation.For carbuncle carbuncle on the back, furuncle, scrofula, burn and scald.

The Rhizoma Atractylodis Macrocephalae is bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, quench the thirst, antiabortive.

Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Be called as the plant that can bleed, function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.Join Chinese angelica blood supplementing, promoting flow of qi by warming channel." decoction pieces is newly joined ": Caulis Spatholobi blood stasis removing blood, tissue regeneration promoting blood, fluent passages through which vital energy circulates.Control summer filthy infection, wind arthralgia due to stagnation of blood disease.Modern medicine is studied, and has antitumaous effect.

Radix Angelicae Sinensis: latin name AngelicaeSinensisRadix, sweet in the mouth, pungent, warm in nature, enter liver, the heart, spleen channel, having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation, cures mainly having a dizzy spell of deficiency of heart-blood, fatigue and weakness, shortness of breath and palpitation, the sea of blood is hollow, the menoxenia of the cold and deficiency of CHONG and REN meridians or congestion retardance, dysmenorrhoea, produces or stomachache, and other blood stasis are had a pain and the card such as the constipation of deficiency of YIN insufficiency of blood dryness of the intestine, its can improve uterus blood circulation, alleviate pelvic congestion, relieving dysmenorrhea.

The traditional Chinese medical science is thought, wind, the extrinsic factor that wet, heat is acute eczema morbidity.Wind is contained and is then itched, wind benefaction and number becomes, therefore acute eczema play is itched, and contaminates general; Wet as the deep heresy having matter, moist glutinous greasy, thus protracted inflammation, recurrent exerbation; Damp and hotly accumulate hematozemia impairment of YIN of a specified duration, cause again insufficiency of the spleen blood dry, failure of skin and muscle to be nourished, so plumpness is chapped, touchingly not to be healed, and endogenous cause of ill is then relevant with the heart, liver, spleen, and with enjoy compose, diet, feelings will etc. are closely related, its pathogeny is dysfunction of the spleen in transportation, retention of damp-heat in the interior, and exopathogenic factor feels wind, heat, damp again, interior foreign minister fights, and fills in pancreas reason and falls ill.According to theory of Chinese medical science, for the pathogeny of acute eczema, with drying damp and strengthening spleen, removing toxic substances rash for the rule for the treatment of, Ilex purpurea Hassk.[I.chinensis Sims, Radix Arnebiae (Radix Lithospermi), Fructus Arctii, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Semen Plantaginis, Rhizoma Coptidis heat-clearing and toxic substances removing in side, expelling pathogenic wind from the body surface, effect of pathogenic fire purging dampness is monarch drug; Herba Taraxaci, Herba Houttuyniae, Herba Andrographis, Fructus Gardeniae (parched), Rhizoma Imperatae, Indigo Naturalis, Radix Gentianae, Herba Dianthi, Radix Sanguisorbae, Folium Isatidis, Radix Ampelopsis heat-clearing and toxic substances removing, removing pus and relieving carbuncle, dispersing swelling and dissipating binds, cooling blood for hemostasis is ministerial drug; The medicines such as Semen Celosiae, Rhizoma Et Radix Notopterygii, Rhizoma Sparganii, Caulis Polygoni Multiflori, Radix Ophiopogonis, Folium Mori are that assistant makes, dispelling wind and removing obstruction in the collateral, clearing away liver-fire, nourishing blood to tranquillize the mind, and lung moistening clears away heart-fire, and enriches blood to invigorate blood circulation, and to strengthen in we monarch drug and ministerial drug is drying damp and strengthening spleen, effect of removing toxic substances rash.

Chinese medicine composition preparation of the present invention is easy, and medicine source is extensive, with low cost, it is in the reduction of patient state of an illness, raise the efficiency, shorten treatment time, prevent recurrence, maintain stable disease, improve life in patients, damage can not be caused to patient body, have no side effect, the aspect such as to have no drug resistance all has remarkable result, thus overcomes the defect that Western medicine drug brings.

Detailed description of the invention

For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with embodiment, technical scheme of the present invention is clearly and completely described.Obviously, described embodiment is a part of the present invention, instead of whole embodiments.Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under without the need to the prerequisite of creative work, all belongs to the scope of protection of the invention.

Embodiment 1:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 5 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Sparganii 12 parts, Herba Houttuyniae 16 parts, Semen Plantaginis 3 parts, Herba Andrographis 12 parts, Fructus Gardeniae (parched) 12 parts, Rhizoma Imperatae 10 parts, Indigo Naturalis 9 parts, Radix Gentianae 15 parts, Herba Dianthi 15 parts, Rhizoma Coptidis 8 parts, Radix Sanguisorbae 5 parts, Caulis Polygoni Multiflori 3 parts, Radix Ophiopogonis 14 parts, Herba Pogostemonis 9 parts, 6 parts, Folium Mori, Fructus Tribuli 8 parts, Semen Coicis 5 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 5 parts, Radix Ampelopsis 16 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Caulis Spatholobi 8 parts, Radix Angelicae Sinensis 5 parts.

Wherein, described Chinese medicine composition is prepared according to following method:

(1) get each medical material according to components by weight percent, add the 10-12 water doubly of medical material gross weight, soak after 45-60 minute, decoct 1 time, decocting time 2 hours, after filtration, adds the 12-13 water doubly of medical material gross weight, decoct the 2nd time, decocting time 3 hours, after filtration, add the 14-15 water doubly of medical material gross weight, decoct the 3rd time, decocting time 4 hours, after filtration, merge 3 filtrates, 120 orders filter, at filtrate heating is concentrated into 60 DEG C, relative density is 1.10 ~ 1.13, obtains concentrated solution, for subsequent use;

(2) added water by gained concentrated solution in step (1) and be adjusted to 2000 parts, filter, sterilizing, obtains abrasive cleaner; Or gained concentrated solution in step (1) being continued heating, to be concentrated into 60 DEG C of relative densities be the thick paste of 1.28-1.33, obtains Chinese medical concrete, described Chinese medical concrete is made ointment, specification: 0.2g crude drug/g ointment.

Embodiment 2:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 13 parts, Radix Gentianae Macrophyllae 6 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Sparganii 20 parts, Herba Houttuyniae 10 parts, Semen Plantaginis 8 parts, Herba Andrographis 5 parts, Fructus Gardeniae (parched) 17 parts, Rhizoma Imperatae 12 parts, Indigo Naturalis 4 parts, Radix Gentianae 20 parts, Herba Dianthi 10 parts, Rhizoma Coptidis 12 parts, Radix Sanguisorbae 2 parts, Caulis Polygoni Multiflori 7 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 15 parts, 3 parts, Folium Mori, Fructus Tribuli 13 parts, Semen Coicis 3 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 5 parts, Folium Isatidis 10 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Caulis Spatholobi 13 parts, Radix Angelicae Sinensis 3 parts.

Preparation method is with embodiment 1.

Embodiment 3:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 5 parts, Radix Arnebiae (Radix Lithospermi) 12 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 9 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Sparganii 13 parts, Herba Houttuyniae 11 parts, Semen Plantaginis 4 parts, Herba Andrographis 6 parts, Fructus Gardeniae (parched) 13 parts, Rhizoma Imperatae 7 parts, Indigo Naturalis 5 parts, Radix Gentianae 18 parts, Herba Dianthi 11 parts, Rhizoma Coptidis 9 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 6 parts, Radix Ophiopogonis 12 parts, Herba Pogostemonis 13 parts, 4 parts, Folium Mori, Fructus Tribuli 9 parts, Semen Coicis 4 parts, Herba Taraxaci 2 parts, Flos Chrysanthemi 6 parts, Folium Isatidis 6 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Caulis Spatholobi 10 parts, Radix Angelicae Sinensis 4 parts.

Preparation method is with embodiment 1.

Embodiment 4:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 11 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 14 parts, Radix Gentianae Macrophyllae 8 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 6 parts, Rhizoma Sparganii 17 parts, Herba Houttuyniae 15 parts, Semen Plantaginis 7 parts, Herba Andrographis 11 parts, Fructus Gardeniae (parched) 16 parts, Rhizoma Imperatae 8 parts, Indigo Naturalis 8 parts, Radix Gentianae 16 parts, Herba Dianthi 14 parts, Rhizoma Coptidis 11 parts, Radix Sanguisorbae 3 parts, Caulis Polygoni Multiflori 5 parts, Radix Ophiopogonis 13 parts, Herba Pogostemonis 14 parts, 5 parts, Folium Mori, Fructus Tribuli 12 parts, Semen Coicis 3 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 9 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Caulis Spatholobi 11 parts, Radix Angelicae Sinensis 3 parts.

Preparation method is with embodiment 1.

Embodiment 5:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 9 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 5 parts, Rhizoma Et Radix Notopterygii 9 parts, Rhizoma Sparganii 15 parts, Herba Houttuyniae 12 parts, Semen Plantaginis 5 parts, Herba Andrographis 9 parts, Fructus Gardeniae (parched) 15 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 7 parts, Radix Gentianae 19 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Caulis Spatholobi 12 parts, Radix Angelicae Sinensis 5 parts.

Preparation method is with embodiment 1.

Embodiment 6:

A kind of Chinese medicine composition being used for the treatment of acute eczema of the present invention, get following traditional Chinese medicine raw medicine: Ilex purpurea Hassk.[I.chinensis Sims 3 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 2 parts, Rhizoma Et Radix Notopterygii 4 parts, Rhizoma Sparganii 19 parts, Herba Houttuyniae 14 parts, Semen Plantaginis 6 parts, Herba Andrographis 7 parts, Fructus Gardeniae (parched) 14 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 6 parts, Radix Gentianae 17 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Caulis Spatholobi 9 parts, Radix Angelicae Sinensis 5 parts.

Preparation method is with embodiment 1.

Acute toxicity test:

Test medicine: the Chinese medical concrete of the made ointment of the embodiment of the present invention 1, adds purified water, be modulated into magma, for subsequent use.

Experimental animal: Kunming mouse, body weight 21g ± 3g, male and female half and half, female mice is all without pregnant.

Process of the test: mouse stomach Chinese medicine magma of the present invention, when given low reaches 460.2g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1.5 hours recover normal, Continuous Observation 7 days after administration, none animal dead, its overall health of patients, diet, take the photograph water, urine and body weight increase all normal.

Result of the test shows: the Chinese medical concrete of the made ointment of mouse stomach embodiment 1, and maximum dosage-feeding is 460.2g crude drug/kg/d (LD ₅₀> 460.2g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.2g crude drug/kg/d; By weighing machine, the tolerance dose of mouse stomach is 2296.3 times of clinical patient.And Chinese medicine preparation of the present invention is herb medicinal paste for external application, point out this medicine acute toxicity extremely low, clinical drug safety.

Long term toxicity test:

Test medicine: the Chinese medical concrete of the made ointment of the embodiment of the present invention 1, adds purified water, be modulated into magma, for subsequent use.

Experimental animal: regular grade SD rat, body weight 202g ± 7g, male and female half and half, female rats is all without pregnant.

Method and result:

Preparation is divided into high, medium and low three dosage groups, and per weight dosage is respectively 180,60,20 times of patient's dose;

Experimental mouse is divided into 10 groups at random, and wherein the Chinese medicine magma of 9 groups of difference gavages, three dosage, remains one group of gavage normal saline (20 times of patient's dose); All 10 groups of all continuous gavages 180 days, observe animal general toxic reaction and the order of severity, check each position, and carry out hematology, the pathological examination of the main organs such as ALT, BUN and the heart, liver, spleen, lung, kidney, stomach after execution by rule of operation; Through long-term feeding, all there is not toxic reaction in 9 groups of rats.Physically well develop.Macroscopic appearance and main organs no abnormality seen.Peripheral hemogram and Serum ALT, BUN compare with matched group and change without pathologic.The all not significant changes such as the pathological replacement heart, liver, spleen, lung, kidney, stomach, therefore, think through proved by pathology, show animal without chronic toxicity.

Clinical reasoning:

In order to verify the effect of Chinese medicine composition of the present invention, in November ,-2014 in July, 2013, the routine acute eczema patient of outpatient service place Stochastic choice 90,15 ~ 62 years old age, the course of disease 1 ~ 12 day, average 8 days.90 routine cases are divided into two groups at random, treatment group 45 example, matched group 45 example.Treatment group and matched group patient are in sex, and at the age, the course of disease, skin lesion, the aspect there was no significant differences such as symptom have comparability.Above patient's Western medicine diagnose standard and tcm diagnosis standard all meet acute eczema.

Exclusion standard:

1. Pregnant and lactant women;

2. merge serious systemic disease;

3. concurrent infection;

4. couple observation drug allergy person;

5. within nearly one week, used antihistamine drug therapist;

6. used corticosteroid hormone person in nearly 2 weeks.

Therapeutic Method:

Treatment group: the Traditional Chinese medicinal abrasive cleaner (namely get this product 100ml warm water to 500ml, mixing) adopting the embodiment of the present invention 3 to prepare is boiled temperature and smoked and wash eczema position, each 15 minutes, every day 3 times.Attention: first should clean affected part by warm water before fumigation and wash method, and then first smoke with medicine juice and wash afterwards.

Matched group: this spit of fland sheet 10mg day of matched group oral imidazole 1 time, every day 3 times.

Treatment group, matched group 1 course for the treatment of on the equal 5th, be used in conjunction 2 courses for the treatment of.

Therapeutic evaluation

By eczema area and severity index (EASI method) standards of grading to erythema, plumpness, skin lesion scope and lichenization carry out 4 grades of scoring: 0=without, 1=is slight, 2=moderate, 3=severe.Pruritus is marked: acute pruritus, and affecting live and work is 3 points; Pruritus but to restrain oneself be 2 points; Slight pruritus is 1 point; It is 0 point without gargalesthesia.Symptom integral decline index (SSRI)=[before (before treatment the rear integration of integration-treatment)/treatment integration] × 100%.

Recovery from illness: SSRI >=95%, pruritus disappears;

Effective: SSRI=60% ~ 94%, pruritus obviously alleviates;

Effective: SSRI=20% ~ 59%, pruritus alleviates;

Invalid: SSRI<20%, pruritus is front or aggravation with treatment.Using recovery from illness, effective and effective percent as total effective rate.Efficacy evaluation is carried out after treating 2 courses for the treatment of.

Statistical method

Measurement data adopts X ± S to represent, compares and adopt χ between group ²inspection, all data all adopt the process of SPSS12.0 statistical software.

Therapeutic outcome

Two groups of therapeutic effect compare in table 1

Table 1 liang group patient effective percentage relative analysis

Group

Number of cases

Cure

Effective

Effectively

Invalid

Effectively total

Treatment group

45

27(60％)

11(24.4％)

5(11.1％)

2(4.4％)

43(95.6％)

Matched group

45

14(31.1％)

11(24.4％)

7(15.6％)

13(28.9％)

32(71.1％)

Wherein, total effective rate=cure rate+obvious effective rate.

Table 1 result shows, the Chinese medicine composition for the treatment of acute eczema of the present invention is more obvious than western medicine effect.In the routine infant of treatments period 90 there is untoward reaction in none example.

Model case:

Case 1

Zhao, man, 51 years old, Qingdao City Laoshan District people.Patient main suit: the coarse plumpness of bilateral skin of dorsum of hand, desquamation companion pruritus more than 5 years; Body is looked into: bilateral the back of the hand symmetrical dense distribution needle point size brown pimple, and skin lesion thickens coarse, accompanies a little desquamation; Diagnosis: eczema; Patient is in outer court Duo Jia hospitalize, and calcium gluconate, the equal effect of diphenhydramine pin do not show, and outer painting hormones ointment can postpone pruritus.Patient tells recent acute pruritus, constipation with dry stool, xerostomia.Red tongue, tongue is few, rapid pulse, is diagnosed as acute eczema, and patient is without relevant gastropathy history, adopt abrasive cleaner external of the present invention, with front boiling temperature, every day 3 times, after 3 days, patient returns, after telling medicine, the state of an illness is clearly better, and pruritus alleviates, free movement of the bowels, and xerostomia takes a turn for the better, depending on its skin lesion place, skin lesion complexion changed is light, and desquamation reduces, and medication is as front, patient's further consultation after 5 days, skin lesion is thinning, and color is obviously thin out, without newly going out skin lesion, after patient tells medicine, skin lesion is not itched substantially, and after 10 days, patient returns, and depending on its skin lesion, is almost recovered.

Case 2

Money, man, 42 years old, Qingdao Jimo people.Patient's abdominal part both sides burst large area eczema, presents erythema in blocks at the beginning, but does not take notice of, there is large stretch of sepage and erosion very soon, pruritus, rear coating Chinese medicine ointment of the present invention, once a day, two days later, scratchiness disappears in coating, sepage and rotten to the corn symptom obviously take a turn for the better, and use 10 days continuously, it is more smooth that eczema area skin has become, erythema is not obvious, continues use 3 days, recovery from illness, follow-up investigation half a year, have no recurrence.

Case 3:

Grandson, man, 41 years old, people from Laiyang, Yantai.Patient drinks back lumbar part burst large area eczema, and red and swollen, pruritus unbearably, occurs large stretch of sepage and erosion, flows out yellow transudate.Rear coating Chinese medicine ointment of the present invention, once a day, after applying one week, scratchiness obviously alleviates, and sepage and rotten to the corn disappearance after 3 days, after 10 days, erythema disappears substantially, completely no longer pruritus.Continue use to fully recover after 7 days, do not recur.

Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the scope of various embodiments of the present invention technical scheme.

Claims (10)

1. be used for the treatment of a Chinese medicine composition for acute eczema, it is characterized in that: the crude drug of described Chinese medicine composition is made up of Ilex purpurea Hassk.[I.chinensis Sims, Radix Arnebiae (Radix Lithospermi), Fructus Arctii, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Semen Celosiae, Rhizoma Et Radix Notopterygii, Rhizoma Sparganii, Herba Houttuyniae, Semen Plantaginis, Herba Andrographis, Fructus Gardeniae (parched), Rhizoma Imperatae, Indigo Naturalis, Radix Gentianae, Herba Dianthi, Rhizoma Coptidis, Radix Sanguisorbae, Caulis Polygoni Multiflori, Radix Ophiopogonis, Herba Pogostemonis, Folium Mori, Fructus Tribuli, Semen Coicis, Herba Taraxaci, Flos Chrysanthemi, Folium Isatidis, Radix Ampelopsis, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Radix Angelicae Sinensis.

2. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 3-6 part, Radix Arnebiae (Radix Lithospermi) 8-13 part, Fructus Arctii 3-5 part, Radix Saposhnikoviae 11-15 part, Radix Gentianae Macrophyllae 5-10 part, Semen Celosiae 2-5 part, Rhizoma Et Radix Notopterygii 4-9 part, Rhizoma Sparganii 12-20 part, Herba Houttuyniae 10-16 part, Semen Plantaginis 3-8 part, Herba Andrographis 5-12 part, Fructus Gardeniae (parched) 12-17 part, Rhizoma Imperatae 7-12 part, Indigo Naturalis 4-9 part, Radix Gentianae 15-20 part, Herba Dianthi 10-15 part, Rhizoma Coptidis 8-12 part, Radix Sanguisorbae 2-5 part, Caulis Polygoni Multiflori 3-7 part, Radix Ophiopogonis 11-14 part, Herba Pogostemonis 9-15 part, Folium Mori 3-6 part, Fructus Tribuli 8-13 part, Semen Coicis 3-5 part, Herba Taraxaci 1-3 part, Flos Chrysanthemi 5-10 part, Folium Isatidis 5-10 part, Radix Ampelopsis 13-16 part, Rhizoma Atractylodis Macrocephalae 3-10 part, Caulis Spatholobi 8-13 part, Radix Angelicae Sinensis 3-5 part.

3. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 5 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Sparganii 12 parts, Herba Houttuyniae 16 parts, Semen Plantaginis 3 parts, Herba Andrographis 12 parts, Fructus Gardeniae (parched) 12 parts, Rhizoma Imperatae 10 parts, Indigo Naturalis 9 parts, Radix Gentianae 15 parts, Herba Dianthi 15 parts, Rhizoma Coptidis 8 parts, Radix Sanguisorbae 5 parts, Caulis Polygoni Multiflori 3 parts, Radix Ophiopogonis 14 parts, Herba Pogostemonis 9 parts, 6 parts, Folium Mori, Fructus Tribuli 8 parts, Semen Coicis 5 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 5 parts, Radix Ampelopsis 16 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Caulis Spatholobi 8 parts, Radix Angelicae Sinensis 5 parts.

4. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 13 parts, Radix Gentianae Macrophyllae 6 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Sparganii 20 parts, Herba Houttuyniae 10 parts, Semen Plantaginis 8 parts, Herba Andrographis 5 parts, Fructus Gardeniae (parched) 17 parts, Rhizoma Imperatae 12 parts, Indigo Naturalis 4 parts, Radix Gentianae 20 parts, Herba Dianthi 10 parts, Rhizoma Coptidis 12 parts, Radix Sanguisorbae 2 parts, Caulis Polygoni Multiflori 7 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 15 parts, 3 parts, Folium Mori, Fructus Tribuli 13 parts, Semen Coicis 3 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 5 parts, Folium Isatidis 10 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Caulis Spatholobi 13 parts, Radix Angelicae Sinensis 3 parts.

5. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 5 parts, Radix Arnebiae (Radix Lithospermi) 12 parts, Fructus Arctii 3 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 9 parts, Semen Celosiae 4 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Sparganii 13 parts, Herba Houttuyniae 11 parts, Semen Plantaginis 4 parts, Herba Andrographis 6 parts, Fructus Gardeniae (parched) 13 parts, Rhizoma Imperatae 7 parts, Indigo Naturalis 5 parts, Radix Gentianae 18 parts, Herba Dianthi 11 parts, Rhizoma Coptidis 9 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 6 parts, Radix Ophiopogonis 12 parts, Herba Pogostemonis 13 parts, 4 parts, Folium Mori, Fructus Tribuli 9 parts, Semen Coicis 4 parts, Herba Taraxaci 2 parts, Flos Chrysanthemi 6 parts, Folium Isatidis 6 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Caulis Spatholobi 10 parts, Radix Angelicae Sinensis 4 parts.

6. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 4 parts, Radix Arnebiae (Radix Lithospermi) 11 parts, Fructus Arctii 4 parts, Radix Saposhnikoviae 14 parts, Radix Gentianae Macrophyllae 8 parts, Semen Celosiae 3 parts, Rhizoma Et Radix Notopterygii 6 parts, Rhizoma Sparganii 17 parts, Herba Houttuyniae 15 parts, Semen Plantaginis 7 parts, Herba Andrographis 11 parts, Fructus Gardeniae (parched) 16 parts, Rhizoma Imperatae 8 parts, Indigo Naturalis 8 parts, Radix Gentianae 16 parts, Herba Dianthi 14 parts, Rhizoma Coptidis 11 parts, Radix Sanguisorbae 3 parts, Caulis Polygoni Multiflori 5 parts, Radix Ophiopogonis 13 parts, Herba Pogostemonis 14 parts, 5 parts, Folium Mori, Fructus Tribuli 12 parts, Semen Coicis 3 parts, Herba Taraxaci 1 part, Flos Chrysanthemi 10 parts, Folium Isatidis 9 parts, Radix Ampelopsis 13 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Caulis Spatholobi 11 parts, Radix Angelicae Sinensis 3 parts.

7. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 6 parts, Radix Arnebiae (Radix Lithospermi) 9 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 12 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 5 parts, Rhizoma Et Radix Notopterygii 9 parts, Rhizoma Sparganii 15 parts, Herba Houttuyniae 12 parts, Semen Plantaginis 5 parts, Herba Andrographis 9 parts, Fructus Gardeniae (parched) 15 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 7 parts, Radix Gentianae 19 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Caulis Spatholobi 12 parts, Radix Angelicae Sinensis 5 parts.

8. the Chinese medicine composition being used for the treatment of acute eczema according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Ilex purpurea Hassk.[I.chinensis Sims 3 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Arctii 5 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 7 parts, Semen Celosiae 2 parts, Rhizoma Et Radix Notopterygii 4 parts, Rhizoma Sparganii 19 parts, Herba Houttuyniae 14 parts, Semen Plantaginis 6 parts, Herba Andrographis 7 parts, Fructus Gardeniae (parched) 14 parts, Rhizoma Imperatae 9 parts, Indigo Naturalis 6 parts, Radix Gentianae 17 parts, Herba Dianthi 13 parts, Rhizoma Coptidis 10 parts, Radix Sanguisorbae 4 parts, Caulis Polygoni Multiflori 4 parts, Radix Ophiopogonis 11 parts, Herba Pogostemonis 11 parts, 5 parts, Folium Mori, Fructus Tribuli 10 parts, Semen Coicis 5 parts, Herba Taraxaci 3 parts, Flos Chrysanthemi 8 parts, Folium Isatidis 8 parts, Radix Ampelopsis 14 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Caulis Spatholobi 9 parts, Radix Angelicae Sinensis 5 parts.

9. the arbitrary described Chinese medicine composition being used for the treatment of acute eczema of claim 3-8, is characterized in that, be prepared in accordance with the following steps:

(1) get each medical material according to components by weight percent, add the 10-12 water doubly of medical material gross weight, soak after 45-60 minute, decoct 1 time, decocting time 2 hours, after filtration, adds the 12-13 water doubly of medical material gross weight, decoct the 2nd time, decocting time 3 hours, after filtration, add the 14-15 water doubly of medical material gross weight, decoct the 3rd time, decocting time 4 hours, after filtration, merge 3 filtrates, 120 orders filter, at filtrate heating is concentrated into 60 DEG C, relative density is 1.10 ~ 1.13, obtains concentrated solution, for subsequent use;

(2) added water by gained concentrated solution in step (1) and be adjusted to 2000 parts, filter, sterilizing, obtains abrasive cleaner; Or gained concentrated solution in step (1) being continued heating, to be concentrated into 60 DEG C of relative densities be the thick paste of 1.28-1.33, obtains Chinese medical concrete, described Chinese medical concrete is made ointment, specification: 0.2g crude drug/g ointment.

10. the application of the Chinese medicine composition being used for the treatment of acute eczema as described in as arbitrary in claim 1-9 in treatment acute eczema medicine.