CN105164249A - 用于诱导细胞至较不成熟状态的方法 - Google Patents

用于诱导细胞至较不成熟状态的方法 Download PDF

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Publication number
CN105164249A
CN105164249A CN201380047947.1A CN201380047947A CN105164249A CN 105164249 A CN105164249 A CN 105164249A CN 201380047947 A CN201380047947 A CN 201380047947A CN 105164249 A CN105164249 A CN 105164249A
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Prior art keywords
cells
cell
muc1
mucl
methods according
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Pending
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CN201380047947.1A
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English (en)
Chinese (zh)
Inventor
辛西娅·巴姆达德
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Minerva Biotechnologies Corp
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Minerva Biotechnologies Corp
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Priority claimed from PCT/US2012/060684 external-priority patent/WO2013059373A2/en
Application filed by Minerva Biotechnologies Corp filed Critical Minerva Biotechnologies Corp
Publication of CN105164249A publication Critical patent/CN105164249A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/04—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C12Y207/04006—Nucleoside-diphosphate kinase (2.7.4.6)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201380047947.1A 2012-07-13 2013-07-15 用于诱导细胞至较不成熟状态的方法 Pending CN105164249A (zh)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US201261671558P 2012-07-13 2012-07-13
US201261671588P 2012-07-13 2012-07-13
US61/671,558 2012-07-13
US61/671,588 2012-07-13
US201261673617P 2012-07-19 2012-07-19
US61/673,617 2012-07-19
US201261675264P 2012-07-24 2012-07-24
US201261675292P 2012-07-24 2012-07-24
US61/675,264 2012-07-24
US61/675,292 2012-07-24
US201261677442P 2012-07-30 2012-07-30
US61/677,442 2012-07-30
US201261679021P 2012-08-02 2012-08-02
US61/679,021 2012-08-02
US201261683155P 2012-08-14 2012-08-14
US61/683,155 2012-08-14
US201261684654P 2012-08-17 2012-08-17
US61/684,654 2012-08-17
US201261693712P 2012-08-27 2012-08-27
US61/693,712 2012-08-27
USPCT/US12/60684 2012-10-17
PCT/US2012/060684 WO2013059373A2 (en) 2011-10-17 2012-10-17 Media for stem cell proliferation and induction
PCT/US2013/050563 WO2014012115A2 (en) 2012-07-13 2013-07-15 Method for inducing cells to less mature state

Publications (1)

Publication Number Publication Date
CN105164249A true CN105164249A (zh) 2015-12-16

Family

ID=49916717

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380047947.1A Pending CN105164249A (zh) 2012-07-13 2013-07-15 用于诱导细胞至较不成熟状态的方法

Country Status (8)

Country Link
US (1) US20150320840A1 (https=)
EP (1) EP2872636B1 (https=)
JP (4) JP6748430B2 (https=)
CN (1) CN105164249A (https=)
AU (3) AU2013289913A1 (https=)
CA (1) CA2879111A1 (https=)
IL (1) IL236692B (https=)
WO (1) WO2014012115A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686418A4 (en) 2011-03-17 2015-04-22 Minerva Biotechnologies Corp METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS
EP2768945B1 (en) 2011-10-17 2022-01-05 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
CN111849874A (zh) * 2012-07-24 2020-10-30 米纳瓦生物技术公司 Nme变体物种表达和抑制
AU2016287603A1 (en) * 2015-07-01 2018-01-25 Minerva Biotechnologies Corporation Method of stem cell-based organ and tissue generation
JP6739758B2 (ja) * 2015-09-25 2020-08-12 三菱瓦斯化学株式会社 細胞培養用基材およびそれを用いた細胞培養方法、細胞培養器、並びに基材としての使用
CN110352238A (zh) * 2017-02-24 2019-10-18 田边刚士 诱导性多能干细胞的制作方法
KR20230028796A (ko) 2020-06-26 2023-03-02 미네르바 바이오테크놀로지 코포레이션 항-nme 항체 및 암 또는 암 전이의 치료 방법
KR20250009592A (ko) 2022-04-12 2025-01-17 미네르바 바이오테크놀로지 코포레이션 항-가변 muc1* 항체 및 그의 용도

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101652469A (zh) * 2006-12-06 2010-02-17 米纳瓦生物技术公司 用于鉴定和操作细胞的方法
CN102239182A (zh) * 2008-10-06 2011-11-09 米纳瓦生物技术公司 Muc1*抗体
CN102272290A (zh) * 2008-10-09 2011-12-07 米纳瓦生物技术公司 用于在细胞中诱导多能性的方法
WO2011159960A2 (en) * 2010-06-16 2011-12-22 Minerva Biotechnologies Corporation Reprogramming cancer cells
CN102549146A (zh) * 2009-06-11 2012-07-04 米纳瓦生物技术公司 用于培养干细胞和祖细胞的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2610292C (en) * 2005-03-30 2015-06-02 Minerva Biotechnologies Corporation Proliferation of muc1 expressing cells
CA2650841A1 (en) * 2005-06-06 2006-12-14 Suomen Punainen Risti, Veripalvelu Method of profiling a cell population
US9144584B2 (en) * 2008-06-11 2015-09-29 Cell4Vet Corporation Adipose tissue-derived stem cells for veterinary use
KR20110134939A (ko) * 2009-04-03 2011-12-15 더 맥클린 하스피털 코퍼레이션 유도된 다능성 줄기 세포
US20120115225A1 (en) * 2009-04-23 2012-05-10 Xu C W Reprogramming of somatic cells with purified proteins
CN103189511B (zh) * 2010-07-12 2016-10-12 国立大学法人鸟取大学 利用siRNA导入的新型hiPSC制作法
WO2012051515A2 (en) * 2010-10-14 2012-04-19 University Of Central Florida Research Foundation, Inc. Cardiac induced pluripotent stem cells and methods of use in repair and regeneration of myocardium
EP2768945B1 (en) * 2011-10-17 2022-01-05 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101652469A (zh) * 2006-12-06 2010-02-17 米纳瓦生物技术公司 用于鉴定和操作细胞的方法
CN102239182A (zh) * 2008-10-06 2011-11-09 米纳瓦生物技术公司 Muc1*抗体
CN102272290A (zh) * 2008-10-09 2011-12-07 米纳瓦生物技术公司 用于在细胞中诱导多能性的方法
CN102549146A (zh) * 2009-06-11 2012-07-04 米纳瓦生物技术公司 用于培养干细胞和祖细胞的方法
WO2011159960A2 (en) * 2010-06-16 2011-12-22 Minerva Biotechnologies Corporation Reprogramming cancer cells

Non-Patent Citations (2)

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Title
A. BILITOU等: "The NM23 family in development", 《MOLECULAR ADN CELLULAR BIOCHEMISTRY》 *
T. DESVIGNES等: "Nme protein family evolutionary history, a vertebrate perspective", 《BMC EVOLUTIONARY BIOLOGY》 *

Also Published As

Publication number Publication date
WO2014012115A3 (en) 2015-04-16
AU2021240117A1 (en) 2021-10-28
JP2019030329A (ja) 2019-02-28
JP6748430B2 (ja) 2020-09-02
JP2016502399A (ja) 2016-01-28
WO2014012115A2 (en) 2014-01-16
EP2872636C0 (en) 2025-06-11
IL236692A0 (en) 2015-02-26
EP2872636B1 (en) 2025-06-11
EP2872636A4 (en) 2016-08-17
EP2872636A2 (en) 2015-05-20
IL236692B (en) 2021-03-25
AU2013289913A1 (en) 2015-03-05
CA2879111A1 (en) 2014-01-16
AU2019203097A1 (en) 2019-05-23
JP2021019592A (ja) 2021-02-18
US20150320840A1 (en) 2015-11-12
JP7501824B2 (ja) 2024-06-18
JP2022101564A (ja) 2022-07-06

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Application publication date: 20151216