CN105079451B - A kind of blue berry blood-sugar reducing tea and preparation method thereof - Google Patents
A kind of blue berry blood-sugar reducing tea and preparation method thereof Download PDFInfo
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Abstract
The invention provides a kind of blue berry blood-sugar reducing tea, its raw material includes blue berry, Blue berry leaf, Fructus Lycii, Radix Puerariae, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Semen Myristicae, Cortex Phellodendri, Radix Liriopes, Rhizoma Polygonati, grass Radix Angelicae Pubescentis, Semen Fagopyri Esculenti, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), Herba Schisandrae intermediae, Radix Hedysari, Semen Euryales, Herba Corydalis Bungeanae, Herba Gerberae Piloselloidis and Rhizoma Et Radix Notopterygii.This blood-sugar reducing tea makes full use of blue berry and the Chinese medicine advantage in terms for the treatment of diabetes, make antidiabetic drug tea beverage, both the peculiar curative effect of Chinese medicine compound had been remained, overcome the drawback of other dosage form, give full play to again the nutritional health function of blue berry, adult child is all willing to accept, and is very suitable for Long-term Oral.
Description
Technical field
The present invention relates to health promoting product technical field, particularly relate to a kind of blue berry blood-sugar reducing tea and preparation method thereof.
Background technology
Blue berry, commonly referred to Fructus vaccini vitis-idaeae, be one of current the most ancient fruit the most in the world, it is estimated general 13,000
Its figure has been had before Nian.Its nutritive value is far above other fruit, can be rated as " king of world's berry ", is
World development fruit variety, fashionable America and Europe the most rapidly in recent years.Blue berry is the fruit that in fruit and vegerable, anthocyanidin content is the highest, cyanine
Element mainly has anti-visual deterioration, blood pressure lowering, slow down aging, anticancer, raising memory, the prevention work such as cardiovascular disease and blood fat reducing
With.
Blue berry has the highest nutritive value and health care, by international food and agricultural organization be classified as the big health food of the mankind five it
One.As the epoch fruit of a kind of health, development and the value of blue berry are the most constantly taken seriously, along with constantly sending out of science
Exhibition and the continuous innovation of technology, the purposes of blue berry and effect by constantly developed for the health of the mankind add one blue
Elegance.
Diabetes are one of three big killers of harm human health, are only second to cancer and cardiovascular and cerebrovascular disease, its sickness rate
There is the trend risen year by year in recent years.It has been reported that, Chinese metropolitan onset diabetes rate (such as Shanghai 10%) has surpassed
Cross U.S.'s (6.3%).Following 20 years, diabetes mellitus in China will spread to cities and towns rapidly, and the vast rural area of Zhongdao is the most climing
Prolong.If do not prevented, within 2025, whole diabetes mellitus in China sickness rate may be up to 20%, and diabetes total population may
Increase to 300,000,000.
The pectin Han 0.41g/100g in Blueberry, pectin belongs to water soluble dietary fiber, regulates post-prandial glycemia, promotes
Intestinal beneficial bacterium is bred, and does not digests chyle fat, cholesterol and heavy metal, effectively prevention and auxiliary treatment heart and brain in purged body
Angiopathy, diabetes, cancer, constipation, the various modern " ciril disease " such as overweight and fat.
Doctor trained in Western medicine hypoglycemic drug diabetes curative effect affirmative, but life-time service needs gradually dosage, mostly has in various degree
Untoward reaction, and complication can not be efficiently controlled.
The TCM treatment of diabetes history of existing thousand of years, first "Nei Jing" record name of disease of quenching one's thirst, and think the five internal organs weak,
Surfeit delicious food, disorder of emotion are to cause the reason quenched one's thirst.Interior-heat is its main pathogenesis." Medical Treasures of the Golden Chamber " vertical special piece of quenching one's thirst, and
Treatment side's medicine is early proposed.Later many doctors clinical characters, complication and clinical classification to quenching one's thirst all has done and has relatively developed,
The clinical syndrome differentiation of today is treated, still has certain guidance meaning.Chinese medicine action temperature is with persistently, and less toxicity, the traditional Chinese medical science occur
Medicine is dialectical flexibly, giving treatment in accordance with the patient’s individuality, integrally-regulated, the health of two-ways regulation patient；Mutiple Targets, multipath, multilevel effect,
The irreplaceable advantage of doctor trained in Western medicine is had for improving index of correlation (blood fat, blood viscosity, microcirculation, antioxidation etc.).
In many Therapeutic Method of the traditional Chinese medical science, Chinese medicine medicated tea is a kind of well Therapeutic Method.Chinese medicine medicated tea also known as medicinal tea,
Will be furnished with Folium Camelliae sinensis or be not furnished with the preparation that the medicine of Folium Camelliae sinensis processes from strand by Chinese herbal medicine (single or compound recipe).Adopt when application more
Take boiling water soak extracting juice clothes or add decocting juice clothes, treatment disease or the effect of health care can be played with epoch tea-drinking.In
The traditional agent treatment of medicine is reformed into and is brewed dietetic therapy, can reach purpose that is the most convenient but also that can guarantee that drug effect.
Present applicant uses theory of Chinese medical science determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, makes full use of blue berry and Chinese medicine in terms for the treatment of diabetes
Advantage, make antidiabetic drug tea beverage, both remained the peculiar curative effect of Chinese medicine compound, and overcome the drawback of other dosage form, fill again
The nutritional health function of blue berry has been waved in distribution, and adult child is all willing to accept, and is very suitable for Long-term Oral.
Summary of the invention
The technical problem to be solved is to provide a kind of blue berry blood-sugar reducing tea, makes full use of blue berry and Chinese medicine in treatment
Advantage in terms of diabetes, makes antidiabetic drug tea beverage, had both remained the peculiar curative effect of Chinese medicine compound, and had overcome other dosage form
Drawback, has given full play to again the nutritional health function of blue berry, and adult child is all willing to accept, and is very suitable for Long-term Oral.
For solving above-mentioned technical problem, the invention provides a kind of blue berry blood-sugar reducing tea, its raw material includes blue berry, blue berry
Leaf, Fructus Lycii, Radix Puerariae, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Semen Myristicae, Cortex Phellodendri, Radix Liriopes, Rhizoma Polygonati, grass Radix Angelicae Pubescentis, Semen Fagopyri Esculenti, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), Herba Schisandrae intermediae,
Radix Hedysari, Semen Euryales, Herba Corydalis Bungeanae, Herba Gerberae Piloselloidis and Rhizoma Et Radix Notopterygii.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 50 weight portion～60 weight portions, indigo plant
Certain kind of berries leaf 35 weight portion～45 weight portions, Fructus Lycii 10 weight portion～20 weight portions, Radix Puerariae 5 weight portion～15 weight portions, Radix Et Caulis Acanthopanacis Senticosi
10 weight portions～20 weight portions, Herba Visci 5 weight portion～15 weight portions, Semen Myristicae 10 weight portion～20 weight portions, Cortex Phellodendri 5 weight
Part～15 weight portions, Radix Liriopes 10 weight portion～20 weight portions, Rhizoma Polygonati 5 weight portion～15 weight portions, grass Radix Angelicae Pubescentis 5 weight portion～15
Weight portion, Semen Fagopyri Esculenti 10 weight portion～20 weight portions, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 5 weight portion～15 weight portions, Herba Schisandrae intermediae 5 weight portion～15 weight portions,
Radix Hedysari 10 weight portion～20 weight portions, Semen Euryales 5 weight portion～15 weight portions, Herba Corydalis Bungeanae 10 weight portion～20 weight portions, hair nail-like boil
Grass 5 weight portions～15 weight portions and Rhizoma Et Radix Notopterygii 10 weight portion～20 weight portions.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 53 weight portion～57 weight portions, indigo plant
Certain kind of berries leaf 38 weight portion～42 weight portions, Fructus Lycii 13 weight portion～17 weight portions, Radix Puerariae 8 weight portion～12 weight portions, Radix Et Caulis Acanthopanacis Senticosi
13 weight portions～17 weight portions, Herba Visci 8 weight portion～12 weight portions, Semen Myristicae 13 weight portion～17 weight portions, Cortex Phellodendri 8 weight
Part～12 weight portions, Radix Liriopes 13 weight portion～17 weight portions, Rhizoma Polygonati 8 weight portion～12 weight portions, grass Radix Angelicae Pubescentis 8 weight portion～12
Weight portion, Semen Fagopyri Esculenti 13 weight portion～17 weight portions, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 8 weight portion～12 weight portions, Herba Schisandrae intermediae 8 weight portion～12 weight portions,
Radix Hedysari 13 weight portion～17 weight portions, Semen Euryales 8 weight portion～12 weight portions, Herba Corydalis Bungeanae 13 weight portion～17 weight portions, hair nail-like boil
Grass 8 weight portions～12 weight portions and Rhizoma Et Radix Notopterygii 13 weight portion～17 weight portions.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 55 weight portion, Blue berry leaf 40 weight
Part, Fructus Lycii 15 weight portion, Radix Puerariae 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15 weight portion, Herba Visci 10 weight portion, Semen Myristicae 15 weight portion,
Cortex Phellodendri 10 weight portion, Radix Liriopes 15 weight portion, Rhizoma Polygonati 10 weight portion, grass Radix Angelicae Pubescentis 10 weight portion, Semen Fagopyri Esculenti 15 weight portion, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 10 weight
Amount part, Herba Schisandrae intermediae 10 weight portion, Radix Hedysari 15 weight portion, Semen Euryales 10 weight portion, Herba Corydalis Bungeanae 15 weight portion, Herba Gerberae Piloselloidis 10 weight portion
With Rhizoma Et Radix Notopterygii 15 weight portion.
Present invention also offers the preparation method of above-mentioned blue berry blood-sugar reducing tea, comprising:
The first step, the process of Blue berry leaf, the choosing of leaf is plucked after fruit harvest, and the leaf on the branch of predetermined beta pruning is adopted
Pluck, and to carry out before blade reddens, clean after harvesting, then carry out the natural drying of 15～20 h, will be dried
Blade load cloth bag, rub 15 min with hand rubbing, be then placed in drying baker at a temperature of 100 DEG C, be dried 1 h, pulverize subsequently
Become powder；
Second step, the process of blue berry, after the fruit that granule is little, colour-difference can not list is picked out, remove branch and leaf
Deng foreign material, clean, drench dry, load refrigerator-freezer pre-freeze, pre-freezing temperature be-30 DEG C, dry, cold-trap is cooled to-35 DEG C in advance, opens dry
Door, loads the blue berry of deep colling, shuts door, starts vacuum pump set and evacuates, and when vacuum reaches 60 Pa, starts
Heating, needs to ensure stable working vacuum degree, and ensures that article maximum temperature is less than 50 DEG C in heating process, the most de-
Water rate reaches 82.6%；
3rd step, prepares Chinese herbal medicine effective extract component powder；
4th step, the Blue berry leaf powder that the first step is obtained, the medium-height grass that the blue berry of second step acquisition and the 3rd step obtain
Medicine effective extract component powder mixes, and ultraviolet-sterilization is sterilized, and contains with Folium Camelliae sinensis bag, it is thus achieved that blue berry blood-sugar reducing tea.
Wherein, described 3rd step is specially further and according to above-mentioned weight portion, each crude drug is respectively crushed into powder, mixed
Close, it is thus achieved that mixed-powder, add the water of in terms of mixed-powder gross weight 3～8 times amount, decoct 2 hours, filter, add in medicinal residues
Enter the water of in terms of mixed-powder gross weight 3～8 times amount, decoct 2 hours, filter, merging filtrate, concentrate and remove water, be dried to powder
End.
Beneficial effects of the present invention:
The present invention provides a kind of blue berry blood-sugar reducing tea, and it makes full use of blue berry and the Chinese medicine advantage in terms for the treatment of diabetes,
Make antidiabetic drug tea beverage, both remained the peculiar curative effect of Chinese medicine compound, and overcome the drawback of other dosage form, give full play to again
The nutritional health function of blue berry, adult child is all willing to accept, and is very suitable for Long-term Oral.
Detailed description of the invention
The invention provides a kind of blue berry blood-sugar reducing tea, its raw material includes blue berry, Blue berry leaf, Fructus Lycii, Radix Puerariae, thorn five
Add, Herba Visci, Semen Myristicae, Cortex Phellodendri, Radix Liriopes, Rhizoma Polygonati, grass Radix Angelicae Pubescentis, Semen Fagopyri Esculenti, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), Herba Schisandrae intermediae, Radix Hedysari, Semen Euryales, Herba Corydalis Bungeanae, hair
Herba Leibnitziae and Rhizoma Et Radix Notopterygii.
Further preferably, described blue berry blood-sugar reducing tea is only prepared from by above-mentioned raw materials.
Each crude drug pharmacology is as follows:
Blue berry: also known as Pericarpium Citri tangerinae, blue berry.Belong to the perennial fallen leaves of Ericaceae Vaccinium or evergreen shrubs, mainly have short clump,
Gao Cong, lagophthalmos and half high clump four major types.Fruit is oblate, is navy blue after maturation.Blueberry contains abundant anthocyanin,
Additionally possibly together with mineral such as carbohydrate, organic acid, cellulose, Vc, flavone, potassium, calcium, phosphorus.Blue berry rich in anthocyanin,
Low sugar, low fat, oxidation resistance is strong, the pectin Han 0.41g/100g in Blueberry, and pectin belongs to water soluble dietary fiber,
Regulation post-prandial glycemia, promotes intestinal beneficial bacterium propagation, does not digests chyle fat, cholesterol and heavy metal, the most in advance in purged body
Anti-and adjuvant therapy of heart cerebrovascular diseases, diabetes, cancer, constipation, the various modern " ciril disease " such as overweight and fat.
Fructus Lycii: latin namelycii fructus, sweet in the mouth, property are flat, enter liver, kidney channel, have liver and kidney tonifying, nourish blood enrich blood, benefit
Shrewd head, the effect of nourishing the lung to arrest cough, be mainly used in liver and kidney deficiency, the soreness of the waist and knees of asthenia of essence and blood, dizziness and tinnitus, seminal emission tinnitus,
Unconsciously sweat and tire；The sexual impotence of insufficiency of kidney-YANG, sterile；Deficiency of YIN-essence, deficiency of liver-blood eyes is dim-sighted and the card such as deficiency of YIN chronic cough, Fructus Lycii
Son can promote liver cell regeneration, the effect of enhancing non-specific immunity function.
Radix Puerariae: latin namePuerariae Lobatae Radix,Sweet in the mouth, pungent, cool in nature, enter spleen, stomach warp, have inspiration gastric qi,
Clearing away heat and promoting production of body fluid, expelling pathogenic factors from muscles is delivered, raw positive, oozes the effect of rash, is mainly used in fever caused by exogenous pathogens, and headache, stiff nape and back, calentura is thirsty, disappears
Yearningly；Diarrhea due to hypofunction of the spleen, clear YANG failing to ascend etc. is demonstrate,proved.
Radix Et Caulis Acanthopanacis Senticosi: for root, rhizome or the stem and leaf of studies on plants of Acanthopanax Miq. in Araliaceae Radix Et Caulis Acanthopanacis Senticosi, latin nameAcanthopanacis Senticosi Radix et Rhizoma seu Caulis, acrid in the mouth, hardship, micro-sweet, warm in nature, enter spleen, kidney, heart channel, there is QI invigorating
Spleen invigorating, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity is soft, be slow in action, body weakness with emaciation
Weak, traumatic injury, fracture, edema, tinea pedis, uncontrolled urination such as are itched at the card.
Herba Visci: bitter in the mouth, sweet, property is put down, is entered liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive effect, uses
In the soreness of waist and knee joint caused by deficiency of the liver and kindey, muscles and bones flaccidity is soft, the foot and knee being feeble, rheumatic arthralgia, articular instability, the tire that asthenia of renal qi causes
The cards such as dynamic uneasiness.
Semen Myristicae: latin namemyristicae semen, acrid in the mouth, bitter, warm in nature, return spleen, stomach, large intestine channel, there is warming middle-JIAO puckery
Intestinal, effect that circulation of qi promoting helps digestion, for diarrhea of deficiency type；Cold-dysentery；Abdominal distention；Lack of appetite is vomitted；Dyspepsia such as does not disappear at the card.
Cortex Phellodendri: bitter in the mouth, cold in nature, to return kidney, bladder, large intestine channel, there is heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat
Effect, for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, tinea pedis, flaccidity wards off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema scabies
The card such as itch.
Radix Liriopes: latin nameliriopes radix, sweet in the mouth, micro-hardship, cold nature, GUIXIN, lung, stomach warp, there is yin nourishing raw
Tianjin, effect that lung moistening clears away heart-fire, for dryness of the lung dry cough, cough due to consumptive disease, the cards such as Tianjin wound is thirsty, vexed insomnia, dryness of the intestine constipation.
Rhizoma Polygonati: sweet in the mouth, property is flat, returns lung, spleen, kidney channel, has nourishing kidney lung moistening, and effect of invigorating the spleen and replenishing QI cures mainly deficiency of YIN chronic cough,
Xeropulmonary cough, insufficiency of the spleen weak, lack of appetite xerostomia, to quench one's thirst, deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, tinnitus mesh is dark, early whitening of beard and hair, and body is empty
Win thin, effect of wind favus disease.
Grass Radix Angelicae Pubescentis: for the root of Araliaceae fogfruit Yunnan Radix Ariliae, bitter in the mouth, pungent, slightly warm in nature, have and dissipate wind
Cold, invigorating spleen for diuresis, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly anemofrigid cold, cough, edema due to deficiency of the spleen, infantile malnutrition, pain in chest and hypochondrium, treating swelling and pain by traumatic injury, wind
Wet pain, lumbago, fracture, menoxenia, traumatic hemorrhage etc. is demonstrate,proved.
Semen Fagopyri Esculenti: for the seed of buckwheat Plant Buckwheat, sweet in the mouth, micro-acid, cold in nature, return spleen, stomach, large intestine channel, have strong
Diabetes involving middle-JIAO amasss, therapeutic method to keep the adverse QI flowing downwards width intestinal, effect of removing toxic substances sore, cures mainly the intestines and stomach and stagnates, has loose bowels, dysentery, nebulousurine, leukorrhagia, spontaneous perspiration, night sweat, bleb
Rash, erysipelas, carbuncle on the back, burn and scald etc. is demonstrate,proved.
Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae): for the root of Buxaceae Sarcococca plant open country fan flower, acrid in the mouth, hardship, property is put down, had promoting flow of QI and blood, only dispel the wind
Effect of pain, cures mainly the cards such as gastritis, stomachache, rheumatalgia.
Herba Schisandrae intermediae: close the rattan of stamen Fructus Schisandrae Chinensis and root for Schisandraceae schisandra plant, bitter in the mouth, pungent, property is put down, and returns liver
Warp, has heat-clearing and toxic substances removing, effect of promoting blood circulation and detumescence, cures mainly influenza, carbuncle sore tumefacting virus, venom, rheumatic numbness, traumatic injury,
Menoxenias etc. are demonstrate,proved.
Radix Hedysari: latin nameRadix Hedysari, sweet in the mouth, warm in nature, return lung, spleen channel, there is invigorating QI to consolidate the body surface resistance, diuresis poison holding,
Evacuation of pus, effect of expelling pus and promoting granulation, cure mainly the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency is certainly
Antiperspirant, deficiency of vital energy edema, the cards such as carbuncle difficulty is routed, blood deficiency and yellow complexion, and interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes.
Semen Euryales: sweet in the mouth, puckery, property is put down.Return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, the function of damp eliminating leukorrhagia stopping, cure mainly
Emission, diarrhea due to hypofunction of the spleen, insufficiency of the spleen nebulousurine, carry inferior card.
Herba Corydalis Bungeanae: latin nameCorydalis Bungeanae Herba, bitter in the mouth, cold in nature, GUIXIN, liver, large intestine channel, have
Heat-clearing and toxic substances removing, effect of mass dissipating and swelling eliminating, cure mainly epidemic disease flu, laryngopharynx swelling and pain, carbuncle carbuncle on the back, treat skin ulcer swell and ache wait demonstrate,prove.
Herba Gerberae Piloselloidis: bitter in the mouth, pungent, property is put down, is had lung qi dispersing cough-relieving, heat-clearing and toxic substances removing, dampness removing, effect of promoting flow of QI and blood, cure mainly
The cough due to common cold, asthma, to have loose bowels, dysentery, edema, stranguria with turbid discharge, epigastric distending pain, treating swelling and pain by traumatic injury, venom etc. is demonstrate,proved.
Rhizoma Et Radix Notopterygii: latin nameNotopterygii Rhizoma et Radix,Acrid in the mouth, hardship, warm in nature, enter kidney, bladder warp, tool
Having effect of relieving exterior syndrome and dispelling cold, expelling wind and dampness, pain relieving, have wind and cold and press from both sides wet exterior syndrome, disease sees that fever with aversion to cold, headache are such as wrapped up in, neck ridge
Stiffback pain, the cards such as limbs are heavy, and joint is ached, anemofrigid-damp arthralgia.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 50 weight portion～60 weight portions, indigo plant
Certain kind of berries leaf 35 weight portion～45 weight portions, Fructus Lycii 10 weight portion～20 weight portions, Radix Puerariae 5 weight portion～15 weight portions, Radix Et Caulis Acanthopanacis Senticosi
10 weight portions～20 weight portions, Herba Visci 5 weight portion～15 weight portions, Semen Myristicae 10 weight portion～20 weight portions, Cortex Phellodendri 5 weight
Part～15 weight portions, Radix Liriopes 10 weight portion～20 weight portions, Rhizoma Polygonati 5 weight portion～15 weight portions, grass Radix Angelicae Pubescentis 5 weight portion～15
Weight portion, Semen Fagopyri Esculenti 10 weight portion～20 weight portions, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 5 weight portion～15 weight portions, Herba Schisandrae intermediae 5 weight portion～15 weight portions,
Radix Hedysari 10 weight portion～20 weight portions, Semen Euryales 5 weight portion～15 weight portions, Herba Corydalis Bungeanae 10 weight portion～20 weight portions, hair nail-like boil
Grass 5 weight portions～15 weight portions and Rhizoma Et Radix Notopterygii 10 weight portion～20 weight portions.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 53 weight portion～57 weight portions, indigo plant
Certain kind of berries leaf 38 weight portion～42 weight portions, Fructus Lycii 13 weight portion～17 weight portions, Radix Puerariae 8 weight portion～12 weight portions, Radix Et Caulis Acanthopanacis Senticosi
13 weight portions～17 weight portions, Herba Visci 8 weight portion～12 weight portions, Semen Myristicae 13 weight portion～17 weight portions, Cortex Phellodendri 8 weight
Part～12 weight portions, Radix Liriopes 13 weight portion～17 weight portions, Rhizoma Polygonati 8 weight portion～12 weight portions, grass Radix Angelicae Pubescentis 8 weight portion～12
Weight portion, Semen Fagopyri Esculenti 13 weight portion～17 weight portions, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 8 weight portion～12 weight portions, Herba Schisandrae intermediae 8 weight portion～12 weight portions,
Radix Hedysari 13 weight portion～17 weight portions, Semen Euryales 8 weight portion～12 weight portions, Herba Corydalis Bungeanae 13 weight portion～17 weight portions, hair nail-like boil
Grass 8 weight portions～12 weight portions and Rhizoma Et Radix Notopterygii 13 weight portion～17 weight portions.
Wherein, in described blue berry blood-sugar reducing tea, the weight portion of each raw material is respectively blue berry 55 weight portion, Blue berry leaf 40 weight
Part, Fructus Lycii 15 weight portion, Radix Puerariae 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15 weight portion, Herba Visci 10 weight portion, Semen Myristicae 15 weight portion,
Cortex Phellodendri 10 weight portion, Radix Liriopes 15 weight portion, Rhizoma Polygonati 10 weight portion, grass Radix Angelicae Pubescentis 10 weight portion, Semen Fagopyri Esculenti 15 weight portion, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 10 weight
Amount part, Herba Schisandrae intermediae 10 weight portion, Radix Hedysari 15 weight portion, Semen Euryales 10 weight portion, Herba Corydalis Bungeanae 15 weight portion, Herba Gerberae Piloselloidis 10 weight portion
With Rhizoma Et Radix Notopterygii 15 weight portion.
Present invention also offers the preparation method of above-mentioned blue berry blood-sugar reducing tea, comprising:
The first step, the process of Blue berry leaf, the choosing of leaf is plucked after fruit harvest, and the leaf on the branch of predetermined beta pruning is adopted
Pluck, and to carry out before blade reddens, clean after harvesting, then carry out the natural drying of 15～20 h, will be dried
Blade load cloth bag, rub 15 min with hand rubbing, be then placed in drying baker at a temperature of 100 DEG C, be dried 1 h, pulverize subsequently
Become powder；
Second step, the process of blue berry, after the fruit that granule is little, colour-difference can not list is picked out, remove branch and leaf
Deng foreign material, clean, drench dry, load refrigerator-freezer pre-freeze, pre-freezing temperature be-30 DEG C, dry, cold-trap is cooled to-35 DEG C in advance, opens dry
Door, loads the blue berry of deep colling, shuts door, starts vacuum pump set and evacuates, and when vacuum reaches 60 Pa, starts
Heating, needs to ensure stable working vacuum degree, and ensures that article maximum temperature is less than 50 DEG C in heating process, the most de-
Water rate reaches 82.6%.
3rd step, prepares Chinese herbal medicine effective extract component powder；
4th step, the Blue berry leaf powder that the first step is obtained, the medium-height grass that the blue berry of second step acquisition and the 3rd step obtain
Medicine effective extract component powder mixes, and ultraviolet-sterilization is sterilized, and contains with Folium Camelliae sinensis bag, it is thus achieved that blue berry blood-sugar reducing tea.
Wherein, described 3rd step is specially further and according to above-mentioned weight portion, each crude drug is respectively crushed into powder, mixed
Close, it is thus achieved that mixed-powder, add the water of in terms of mixed-powder gross weight 3～8 times amount, decoct 2 hours, filter, add in medicinal residues
Enter the water of in terms of mixed-powder gross weight 3～8 times amount, decoct 2 hours, filter, merging filtrate, concentrate and remove water, be dried to powder
End.
Embodiment is below used to describe embodiments of the present invention in detail, whereby to the present invention how application technology means
Solve technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese herbal medicine extracting powder
Each Fructus Lycii 15g, Radix Puerariae 10g, Radix Et Caulis Acanthopanacis Senticosi 15g, Herba Visci 10g, Semen Myristicae 15g, Cortex Phellodendri 10g, Radix Liriopes 15g,
Rhizoma Polygonati 10g, grass Radix Angelicae Pubescentis 10g, Semen Fagopyri Esculenti 15g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 10g, Herba Schisandrae intermediae 10g, Radix Hedysari 15g, Semen Euryales 10g, Herba Corydalis Bungeanae 15g, hair nail-like boil
Grass 10g and Rhizoma Et Radix Notopterygii 15g is respectively crushed into powder, and mixing, it is thus achieved that mixed-powder adds the water of 1kg, decocts 2 hours, filters,
Medicinal residues add the water of 1kg, decocts 2 hours, filter, merging filtrate, concentrate and remove water, be dried to powder.
Embodiment 2 Chinese herbal medicine extracting powder
Each Fructus Lycii 12g, Radix Puerariae 7g, Radix Et Caulis Acanthopanacis Senticosi 12g, Herba Visci 7g, Semen Myristicae 12g, Cortex Phellodendri 7g, Radix Liriopes 12g, Rhizoma Polygonati
7g, grass Radix Angelicae Pubescentis 7g, Semen Fagopyri Esculenti 12g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 7g, Herba Schisandrae intermediae 7g, Radix Hedysari 12g, Semen Euryales 7g, Herba Corydalis Bungeanae 12g, Herba Gerberae Piloselloidis 7g and Rhizoma Et Radix Notopterygii
12g is respectively crushed into powder, mixing, it is thus achieved that mixed-powder, adds the water of 1kg, decocts 2 hours, filters, and adds in medicinal residues
The water of 1kg, decocts 2 hours, filters, merging filtrate, concentrates and removes water, is dried to powder.
Embodiment 3 Chinese herbal medicine extracting powder
Each Fructus Lycii 18g, Radix Puerariae 13g, Radix Et Caulis Acanthopanacis Senticosi 18g, Herba Visci 13g, Semen Myristicae 18g, Cortex Phellodendri 13g, Radix Liriopes 18g,
Rhizoma Polygonati 13g, grass Radix Angelicae Pubescentis 13g, Semen Fagopyri Esculenti 18g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 13g, Herba Schisandrae intermediae 13g, Radix Hedysari 18g, Semen Euryales 13g, Herba Corydalis Bungeanae 18g, hair nail-like boil
Grass 13g and Rhizoma Et Radix Notopterygii 18g is respectively crushed into powder, and mixing, it is thus achieved that mixed-powder adds the water of 1kg, decocts 2 hours, filters,
Medicinal residues add the water of 1kg, decocts 2 hours, filter, merging filtrate, concentrate and remove water, be dried to powder.
Embodiment 4 blue berry blood-sugar reducing tea
The process of Blue berry leaf, the choosing of leaf is plucked after fruit harvest, and the leaf on the branch of predetermined beta pruning is plucked, and wants
Carry out before blade reddens, clean after harvesting, then carry out the natural drying of 15～20 h, dried blade is loaded
Cloth bag, rubs 15 min with hand rubbing, is then placed on drying baker interior at a temperature of 100 DEG C, is dried 1 h, is ground into powder, blue berry subsequently
The process of fruit, after the fruit that granule is little, colour-difference can not list is picked out, removes the foreign material such as branch and leaf, cleans, drenches dry, dress
Entering refrigerator-freezer pre-freeze, pre-freezing temperature is-30 DEG C, is dried, cold-trap is cooled to-35 DEG C in advance, opens dry door, loads the blue berry of deep colling
Really, shut door, start vacuum pump set and evacuate, when vacuum reaches 60 Pa, begin to warm up, heating process needs
Ensureing stable working vacuum degree, and ensure that article maximum temperature is less than 50 DEG C, average dehydration reaches 82.6%, by front
Blue berry leaf powder 55g, blue berry 40g and Chinese herbal medicine effective extract component powder of embodiment 1 acquisition that face obtains are blended in one
Rising, ultraviolet-sterilization is sterilized, and contains with Folium Camelliae sinensis bag, it is thus achieved that blue berry blood-sugar reducing tea.
Embodiment 5 toxicity detection
Acute toxicity testing
Test method: with the embodiment of the present invention 4 obtain blue berry blood-sugar reducing tea as object, select 20 adult white mouse to try
Test, the 30g of consumption per day, be immersed in the water decoction 1 hour, to the 10 of test group white mouse gavages, observe 7.10 white mouse as a result
All strong depositing, its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Toxicity test proves, this blood-sugar reducing tea is not
Toxic effect and untoward reaction, clinical practice is safe and reliable.
Chronic toxicity test
Test method: with the blue berry blood-sugar reducing tea of the embodiment of the present invention 4 as object, take 80 ripe vital signs identical
Its random division, as object, male and female half-and-half, is 2 groups by rabbit, 1 blank group and 1 test group, often group 40, comparison
Group fills feeds water, the water that the blue berry blood-sugar reducing tea that test group gavage embodiment 4 obtains is soaked, and consumption per day 5g decocts in water 1 hour and fills
Stomach.Medication is carried out 30 days, by the behavior of rabbit before comparing medication, after medication 30 days and drug withdrawal 30 days, the mental status,
Feces etc. change, and carry out the toxicity detection of medicine.By observing the rabbit of test group, the rabbit after medicine feed, in behavior, essence
God's aspect such as state and feces, and the rabbit do not offerd medicine, without any difference.Therefore, this medicine long-term taking, not there is accumulation
Toxicity, will not deposit toxin in vivo.
Embodiment 6 animal effect experimental
Material: the blue berry blood-sugar reducing tea of embodiment 1 preparation
Reagent: metformin hydrochloride tablet (Beijing Sihuan Pharmaceutical Co., Ltd)；Alloxan (Fluka product)；Sodium chloride
Injection (0.9%, Siyao Co., Ltd., Shijiazhuang)；Noradrenaline bitartrate (the limited public affairs of Shanghai He Feng pharmacy
Department)；Chloroform, n-butyl alcohol, glucose, concentrated sulphuric acid are analytical pure.
Instrument: TU-1810 ultraviolet spectrophotometer (Beijing Puxi General Instrument Co., Ltd)；PH counts PHB24
(Shanghai Precision Scientific Apparatus Co., Ltd)；HH-4 type digital display thermostat water bath；101A-3 type electric drying oven with forced convection；800-
B type desk centrifuge (Anting Scientific Instrument Factory, Shanghai)；Electronic balance；Xi Beile pulverizer；SHZ-D circulating water type vacuum pump
(Ying Yu Yu Hua instrument plant of Gongyi City), the superior blood-sugar detecting instrument of Roche, Roche sugar Test paper (Roche Diagnostics GmbH).Rotation
Turn vaporizer RE2 52C (Shanghai Yarong Biochemical Instrument Plant).
Laboratory animal: Kun Ming mice, body weight 22 ~ 24 g, male and female half and half.
Normal mouse experimental technique: take healthy mice 60, is randomly divided into matched group, metformin hydrochloride group
(125mg/kg d) and blue berry blood-sugar reducing tea group (200mg/kg d), often group 20, matched group gives equal-volume normal saline, often
It gavage 1 time, continuous 14 d, 5 d, 7 d, 14 d after being administered, eye socket takes blood, measures blood sugar level.
The blood sugar lowering of adrenaline-induced hyperglycosemia rats is tested: take healthy mice 80, be randomly divided into normal control
Group, epinephrine group, metformin hydrochloride group (125 mg/kg d) and blue berry blood-sugar reducing tea group (200mg/kg d), often organize 20
Only, every day gastric infusion 1 time, Normal group and epinephrine group give normal saline (NS), successive administration 2 weeks
After.Last is administered front 12 h fasting, and after gastric infusion 2.0 h in addition to normal group injecting normal saline, remaining is all by 2 mg/
Kg lumbar injection norepinephrine, after 30 min, eye socket takes blood, measures blood sugar level.
Alloxan is caused the blood sugar lowering test of diabetic mice
Selecting healthy mice 80, fasting 12 h pneumoretroperitoneum injects alloxan 200 mg/kg, after 3 d, fasting
5 h, cut tail point and take blood survey blood glucose, and filtering out fasting glucose the mice of 11.1 more than mmol/L is diabetic mice, mice
Being randomly divided into hyperglycemia model group, blue berry blood-sugar reducing tea group, medication therapy groups (metformin hydrochloride group) is positive controls, 0.9%
Normal saline is negative control group, often group 20, and blue berry blood-sugar reducing tea group is by the dosed administration of 400 mg/kg d, hydrochloric acid two
First biguanide group by the dosed administration of 125 mg/kg d, hyperglycemia model group and the isopyknic normal saline of Normal group,
Being administered 1 successive administration every day 2 weeks, last is administered front 12 h fasting, and after last is administered 2 h, eye socket takes blood, mensuration
Blood sugar level.
The carbohydrate tolerance test of hyperglycemia model mice
Take alloxan and cause hyperglycemia model mice 60, be randomly divided into 3 groups: hyperglycemia model group, Drug therapy
Group (metformin hydrochloride group) is positive controls, blue berry blood-sugar reducing tea group (200 mg/kg d), often group 20.Take 20 to be good for
Health mice is blue berry blood-sugar reducing tea group (200 mg/kg), and medication, dosage are tested with adrenaline-induced hyperglycosemia rats.4
Group mice continuous processing 14 d, before being administered last day, water 12 h is can't help in fasting, after being administered 3 h, gives glucose 2.5 g/
Kg gavage, in 0,0.5,1.0,4 phases of 2.0h detect blood glucose with the superior blood-sugar detecting instrument of Roche respectively.Carry out carbohydrate tolerance
Experiment.
Mathematical statistics
Experimental data with mean+SD (± SD) represent, use SPSS15.0 software that data are carried out Dan Yin
Element variance statistic analysis, group difference uses Duncan multiple comparisons, and significant level is P < 0.05.
Conclusion
Impact on normal mouse blood sugar, the results are shown in Table 1.
The table 1 impact on normal mouse blood sugar
Continuously after gavage 14 d, the blood glucose value of each time point and matched group blood during testing after normal mouse gavage polysaccharide
Sugar value change is consistent, compares with matched group, nonsignificance.Metformin hydrochloride group then significantly reduces the normal blood of mice
Sugar (table 1).This shows, often takes blue berry blood-sugar reducing tea and the blood glucose value of normal mouse will not be produced impact.
Impact on adrenaline-induced hyperglycosemia rats blood glucose, the results are shown in Table 2.
The table 2 impact on adrenaline-induced hyperglycosemia rats blood glucose
| Group | Dosage (mg/kg) | Fasting blood sugar |
| Normal group | NS | 5.61+0.92 |
| Epinephrine model group | NS | 11.93+1.17 |
| Metformin hydrochloride group | 125 | 7.93+1.02 |
| Blue berry blood-sugar reducing tea group | 200 | 5.71+0.83 |
Table 2 result shows, the blood glucose value of blue berry blood-sugar reducing tea group compares with epinephrine model group, difference extremely notable (P <
0.01), blood glucose value, close to normal mouse blood sugar level, shows that blue berry blood-sugar reducing tea group has suppression epinephrine induced mice blood glucose
The effect raised.
Table 3 causes the impact of hyperglycemia mouse blood sugar to alloxan
In table 3, result shows, after administration, the blood glucose value of blue berry blood-sugar reducing tea group compares with alloxan model group, difference
Extremely notable (P < 0.01).Blue berry blood-sugar reducing tea group mice elevated blood glucose levels is efficiently controlled, and can effectively reduce diabetes little
Mus elevated blood glucose levels, has no effect on normal mouse blood sugar level.Result display blue berry blood-sugar reducing tea group can reduce experimental hyperglycemia
Mouse blood sugar.
Table 4 causes the impact of hyperglycemia glucose tolerance in mice to alloxan
Table 4 result shows, 1.0 h and 2.0 h blood glucose are raised by blue berry blood-sugar reducing tea group inhibitory action (P ＜
0.05).The mice of gavage polysaccharide 0,0.5,1.0,2.0 h time blood glucose value compared with model group, reduce extremely notable (P ＜
0.01), it is seen then that the effect in terms of diabetes-alleviating glucose tolerance in mice reduction of blue berry blood-sugar reducing tea group is notable, has reached medicine group
Treatment level.After normal mouse gavage polysaccharide, the blood glucose value when 0.5 h is higher, elapses over time, 1.0,2.0 h blood
Sugar value is gradually reduced, and tends to be steady.Illustrate that Anji Ramulus et Folium Mussaendae Pubescentis polysaccharide has no effect on the carbohydrate tolerance of normal mouse.
All above-mentioned primary these intellectual properties of enforcement, do not set this new product of enforcement limiting other forms
And/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar execution feelings
Condition.But, all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only presently preferred embodiments of the present invention, is not the restriction that the present invention makees other form, appoints
What those skilled in the art changed possibly also with the technology contents of the disclosure above or be modified as equivalent variations etc.
Effect embodiment.But every without departing from technical solution of the present invention content, the technical spirit of the foundation present invention is to above example institute
Any simple modification, equivalent variations and the remodeling made, still falls within the protection domain of technical solution of the present invention.
Claims (5)
1. one kind is used for blue berry blood-sugar reducing tea, it is characterised in that: raw material is by blue berry, Blue berry leaf, Fructus Lycii, Radix Puerariae, Radix Et Caulis Acanthopanacis Senticosi, Mongolian oak
Parasitism, Semen Myristicae, Cortex Phellodendri, Radix Liriopes, Rhizoma Polygonati, grass Radix Angelicae Pubescentis, Semen Fagopyri Esculenti, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), Herba Schisandrae intermediae, Radix Hedysari, Semen Euryales, Herba Corydalis Bungeanae, hair nail-like boil
Grass and Rhizoma Et Radix Notopterygii are constituted；
The weight portion of each raw material is respectively blue berry 50 weight portion～60 weight portions, Blue berry leaf 35 weight portion～45 weight portions, Chinese holly
Fructus Lycii 10 weight portion～20 weight portions, Radix Puerariae 5 weight portion～15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 10 weight portion～20 weight portions, Herba Visci 5
Weight portion～15 weight portions, Semen Myristicae 10 weight portion～20 weight portions, Cortex Phellodendri 5 weight portion～15 weight portions, Radix Liriopes 10 weight
Part～20 weight portions, Rhizoma Polygonati 5 weight portion～15 weight portions, grass Radix Angelicae Pubescentis 5 weight portion～15 weight portions, Semen Fagopyri Esculenti 10 weight portion～20 weights
Amount part, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 5 weight portion～15 weight portions, Herba Schisandrae intermediae 5 weight portion～15 weight portions, Radix Hedysari 10 weight portion～20 weight portions, Gorgon euryale
Real 5 weight portions～15 weight portions, Herba Corydalis Bungeanae 10 weight portion～20 weight portions, Herba Gerberae Piloselloidis 5 weight portion～15 weight portions and Rhizoma Et Radix Notopterygii
10 weight portions～20 weight portions.
2. blue berry blood-sugar reducing tea as claimed in claim 1, it is characterised in that: the weight portion of each raw material is respectively blue berry 53 weight
Part～57 weight portions, Blue berry leaf 38 weight portion～42 weight portions, Fructus Lycii 13 weight portion～17 weight portions, Radix Puerariae 8 weight portion～
12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 13 weight portion～17 weight portions, Herba Visci 8 weight portion～12 weight portions, Semen Myristicae 13 weight portion～17
Weight portion, Cortex Phellodendri 8 weight portion～12 weight portions, Radix Liriopes 13 weight portion～17 weight portions, Rhizoma Polygonati 8 weight portion～12 weight portions,
Grass Radix Angelicae Pubescentis 8 weight portion～12 weight portions, Semen Fagopyri Esculenti 13 weight portion～17 weight portions, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 8 weight portion～12 weight portions, Herba Schisandrae intermediae 8
Weight portion～12 weight portions, Radix Hedysari 13 weight portion～17 weight portions, Semen Euryales 8 weight portion～12 weight portions, Herba Corydalis Bungeanae 13 weight portion
～17 weight portions, Herba Gerberae Piloselloidis 8 weight portion～12 weight portions and Rhizoma Et Radix Notopterygii 13 weight portion～17 weight portions.
3. blue berry blood-sugar reducing tea as claimed in claim 1 or 2, it is characterised in that: the weight portion of each raw material is respectively blue berry 55
Weight portion, Blue berry leaf 40 weight portion, Fructus Lycii 15 weight portion, Radix Puerariae 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15 weight portion, Herba Visci 10 weight
Part, Semen Myristicae 15 weight portion, Cortex Phellodendri 10 weight portion, Radix Liriopes 15 weight portion, Rhizoma Polygonati 10 weight portion, grass Radix Angelicae Pubescentis 10 weight portion, buckwheat
Wheat 15 weight portion, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 10 weight portion, Herba Schisandrae intermediae 10 weight portion, Radix Hedysari 15 weight portion, Semen Euryales 10 weight portion, Herba Corydalis Bungeanae 15 weight
Part, Herba Gerberae Piloselloidis 10 weight portion and Rhizoma Et Radix Notopterygii 15 weight portion.
4. the preparation method of blue berry blood-sugar reducing tea described in claim 1 or 2, it is characterised in that including:
The first step, the process of Blue berry leaf, the choosing of leaf is plucked after fruit harvest, and the leaf on the branch of predetermined beta pruning is plucked, and
And to carry out before blade reddens, clean after harvesting, then carry out the natural drying of 15～20 h, by dried blade
Load cloth bag, rub 15 min with hand rubbing, be then placed on drying baker interior at a temperature of 100 DEG C, be dried 1 h, be ground into powder subsequently；
Second step, the process of blue berry, after the fruit that granule is little, colour-difference can not list is picked out, remove branch and leaf etc. miscellaneous
Thing, clean, drench dry, load refrigerator-freezer pre-freeze, pre-freezing temperature be-30 DEG C, dry, cold-trap is cooled to-35 DEG C in advance, opens dryness storehouse
Door, loads the blue berry of deep colling, shuts door, starts vacuum pump set and evacuates, when vacuum reaches 60 Pa, starts to add
Heat, needs to ensure stable working vacuum degree, and ensures that article maximum temperature is less than 50 DEG C in heating process, average dehydration
Rate reaches 82.6%；
3rd step, prepares Chinese herbal medicine effective extract component powder；
4th step, the Blue berry leaf powder first step obtained, blue berry and the Chinese herbal medicine of the 3rd step acquisition that second step obtains have
Effect extract component powder mixes, and ultraviolet-sterilization is sterilized, and contains with Folium Camelliae sinensis bag, it is thus achieved that blueberry health preservation tea.
5. the preparation method of blue berry blood-sugar reducing tea described in claim 4, it is characterised in that: described 3rd step is specially further will be each
Crude drug is respectively crushed into powder according to above-mentioned weight portion, mixing, it is thus achieved that mixed-powder, adds in terms of mixed-powder gross weight 3
～8 water of times amount, decoct 2 hours, filter, medicinal residues add the water of in terms of mixed-powder gross weight 3～8 times amount, decoct 2 little
Time, filter, merging filtrate, concentrate and remove water, be dried to powder.
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