CN105073179B - 经皮药物递送装置 - Google Patents

经皮药物递送装置 Download PDF

Info

Publication number
CN105073179B
CN105073179B CN201480009137.1A CN201480009137A CN105073179B CN 105073179 B CN105073179 B CN 105073179B CN 201480009137 A CN201480009137 A CN 201480009137A CN 105073179 B CN105073179 B CN 105073179B
Authority
CN
China
Prior art keywords
drug delivery
reservoir
delivery device
transdermal drug
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480009137.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN105073179A (zh
Inventor
R·F·罗斯
L·哈根
A·马尔金
D·哈切特
J·马克斯
T·卢茨欧
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sorrento Therapeutics Inc
Original Assignee
Kimberly Clark Worldwide Inc
Sorrento Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Worldwide Inc, Sorrento Therapeutics Inc filed Critical Kimberly Clark Worldwide Inc
Priority to CN201910125304.3A priority Critical patent/CN109621083B/zh
Publication of CN105073179A publication Critical patent/CN105073179A/zh
Application granted granted Critical
Publication of CN105073179B publication Critical patent/CN105073179B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1587—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body suitable for being connected to an infusion line after insertion into a patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201480009137.1A 2013-02-28 2014-02-28 经皮药物递送装置 Expired - Fee Related CN105073179B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910125304.3A CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361770639P 2013-02-28 2013-02-28
US61/770639 2013-02-28
PCT/IB2014/059345 WO2014132240A1 (en) 2013-02-28 2014-02-28 Transdermal drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910125304.3A Division CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Publications (2)

Publication Number Publication Date
CN105073179A CN105073179A (zh) 2015-11-18
CN105073179B true CN105073179B (zh) 2019-03-19

Family

ID=51427583

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480009137.1A Expired - Fee Related CN105073179B (zh) 2013-02-28 2014-02-28 经皮药物递送装置
CN201910125304.3A Expired - Fee Related CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201910125304.3A Expired - Fee Related CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Country Status (11)

Country Link
US (3) US10183156B2 (https=)
EP (1) EP2961471B1 (https=)
JP (2) JP6522523B2 (https=)
KR (3) KR102571835B1 (https=)
CN (2) CN105073179B (https=)
AU (1) AU2014222308B2 (https=)
BR (1) BR112015020328B1 (https=)
CA (1) CA2901568C (https=)
MX (1) MX360121B (https=)
RU (1) RU2622605C2 (https=)
WO (1) WO2014132240A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107613853A (zh) * 2015-01-23 2018-01-19 马尔西奥·马克·阿布雷乌 用于皮肤处理的设备和方法
PL3325081T3 (pl) 2015-07-24 2021-12-20 Sorrento Therapeutics, Inc. Sposoby dostarczania limfatycznego środków czynnych
BR112018001292A2 (pt) 2015-07-24 2018-09-11 Kimberly Clark Co métodos para melhor liberação de agentes ativos a tumores
BR112018012526B1 (pt) * 2015-12-21 2022-08-09 Medrx Co., Ltd Alojamento de aplicador de adesivo de microagulha, e, aplicador de adesivo de microagulha
KR101672671B1 (ko) * 2016-03-03 2016-11-03 김경원 석션 니들 부재와 결합되는 환형 밀착캡을 갖는 오토 인젝터 핸드피스
JP6726512B2 (ja) * 2016-03-31 2020-07-22 コスメディ製薬株式会社 マイクロニードルアプリケータ
US11311708B2 (en) * 2016-04-29 2022-04-26 Sorrento Therapeutics, Inc. Microneedle array assembly and fluid delivery apparatus having such an assembly
CA3031059C (en) * 2016-07-18 2023-04-04 Siemens Healthcare Diagnostics Inc. Biofouling prevention of wearable sensors and methods of use and calibration related thereto
KR101933767B1 (ko) * 2016-09-05 2018-12-28 (의료)길의료재단 발기부전 환자를 위한 콘돔
US11266344B2 (en) 2016-09-21 2022-03-08 Samsung Electronics Co., Ltd. Method for measuring skin condition and electronic device therefor
WO2018096534A1 (en) 2016-11-22 2018-05-31 Sorrel Medical Ltd. Apparatus for delivering a therapeutic substance
WO2018132430A1 (en) * 2017-01-10 2018-07-19 A.T. Still Universiy Fluid infusion system
JP6931217B2 (ja) * 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
WO2018213579A1 (en) * 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-actuating articles
USD895109S1 (en) * 2017-10-18 2020-09-01 Roche Diabetes Care, Inc. Inserter for an infusion set
CN109718421B (zh) * 2017-10-27 2022-04-29 研能科技股份有限公司 穿戴式人体胰岛素注入供液装置
AU2019269636A1 (en) 2018-05-17 2020-11-19 Massachusetts Institute Of Technology Systems for electrical stimulation
EP3603489A1 (fr) * 2018-08-03 2020-02-05 PKvitality Système de surveillance corporelle avec liaison séparable
AU2019352635B2 (en) * 2018-10-02 2024-12-19 WearOptimo Pty Ltd Actuator system
WO2020069568A1 (en) 2018-10-02 2020-04-09 WearOptimo Pty Ltd Treatment delivery system
EP3744368B1 (en) 2018-10-05 2026-02-18 LTS Device Technologies Ltd Triggering sequence
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
CN109966636B (zh) * 2019-04-17 2025-01-24 苏州微亮生物科技有限公司 一种给药导入装置
BR112022005788A2 (pt) 2019-10-01 2022-06-21 Unomedical As Conector
JP2023505231A (ja) 2019-12-05 2023-02-08 ソレント・セラピューティクス・インコーポレイテッド リンパ管送達デバイスによる抗ｐｄ－１または抗ｐｄ－ｌ１治療剤の投与による癌の処置方法
JP7649574B2 (ja) 2020-10-06 2025-03-21 イオフロー・カンパニー・リミテッド 薬液注入装置
KR102548189B1 (ko) * 2020-10-20 2023-06-28 이오플로우(주) 약액 주입 장치
CN117813128A (zh) 2021-01-22 2024-04-02 索伦托药业有限公司 用于微升级淋巴递送冠状病毒疫苗的装置
WO2022192594A2 (en) 2021-03-11 2022-09-15 Sorrento Therapeutics, Inc. Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US20240279339A1 (en) 2021-06-09 2024-08-22 Vivasor, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
CN117836023A (zh) 2021-07-23 2024-04-05 康沃特克有限公司 具有穿刺机构的端口
JP2024531337A (ja) 2021-08-18 2024-08-29 ソレント・セラピューティクス・インコーポレイテッド リンパ系を標的化する治療剤
CN115738042B (zh) * 2022-11-15 2026-02-24 中国人民解放军联勤保障部队第九〇〇医院 一种纽扣式自动镇痛装置
CN116585606A (zh) * 2023-06-15 2023-08-15 徕兄健康科技(威海)有限责任公司 一种可自调节的局部麻醉用微针贴片
WO2025129128A1 (en) 2023-12-15 2025-06-19 Vivasor, Inc. Compositions and methods for non-viral delivery of therapeutic compounds
KR20250136558A (ko) * 2024-03-08 2025-09-16 주식회사 케어메디 약물 주입 장치의 주입관을 대상체에 삽입시키기 위한 어플리케이터 및 이를 포함하는 약물 주입 시스템

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
CN1571685A (zh) * 2001-09-12 2005-01-26 贝克顿迪肯森公司 用于药物传送的微针为基础的笔装置和使用该装置的方法
CN101801452A (zh) * 2007-08-06 2010-08-11 宁静制药公司 用于去氨加压素药物给送的方法和设备
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
US20110022002A1 (en) * 2008-12-16 2011-01-27 Medtronic Minimed, Inc. Needle insertion systems and methods
US20110288526A1 (en) * 2008-11-07 2011-11-24 Min Wei Pen Needle Assembly For Intradermal Injection
CN102725019A (zh) * 2010-01-08 2012-10-10 威斯康星校友研究基金会 用于基于微针的药物递送设备的囊状装置

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
TW279133B (https=) 1990-12-13 1996-06-21 Elan Med Tech
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
CA2313698C (en) * 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
ES2182379T3 (es) 1997-12-22 2003-03-01 Alza Corp Membrana de regulacion del regimen de liberacion para dispositivos de administracion controlada de farmacos.
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6251079B1 (en) * 1998-09-30 2001-06-26 C. R. Bard, Inc. Transthoracic drug delivery device
AUPP985099A0 (en) 1999-04-20 1999-05-13 Usf Filtration And Separations Group Inc. Membrane filtration manifold system
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
HK1048604B (en) * 1999-12-10 2006-05-04 Alza Corporation Device and method for enhancing microprotrusion skin piercing
US20030014014A1 (en) 2000-02-10 2003-01-16 Zvi Nitzan Drug delivery device and method
WO2001070309A1 (en) * 2000-03-23 2001-09-27 Antares Pharma, Inc. Single use disposable jet injector
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6656147B1 (en) 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
CA2425312C (en) * 2000-10-13 2010-02-16 Alza Corporation Microprotrusion member retainer for impact applicator
AU2002330083A1 (en) 2001-09-21 2003-04-01 Biovalve Technologies, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
KR20120087197A (ko) * 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
EP1590034B1 (en) 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Microneedle array patch
EP1475113A1 (en) 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
CN2657686Y (zh) * 2003-09-25 2004-11-24 李玉红 输液器针头助扎定位支架
KR20060099520A (ko) 2003-10-21 2006-09-19 노보 노르디스크 에이/에스 의료용 피부 장착 장치
AU2004283018A1 (en) 2003-10-21 2005-05-06 Novo Nordisk A/S Medical injection device mountable to the skin
EP2179754B1 (en) 2003-10-23 2016-06-01 Novo Nordisk A/S Medical injection device mountable to the skin
WO2005049108A2 (en) 2003-11-13 2005-06-02 Alza Corporation System and method for transdermal delivery
RU2006119485A (ru) * 2003-12-18 2008-01-27 Ново Нордиск А/С (DK) Струйное устройство для инъекций и способ ввода лекарств через кожу
CA2560840C (en) 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
US7537590B2 (en) 2004-07-30 2009-05-26 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
EP1790375A4 (en) 2004-08-12 2009-06-17 Hisamitsu Pharmaceutical Co TRANSDERMAL MEDICINE ADMINISTRATION WITH MICRONADEL
US7699802B2 (en) * 2005-05-03 2010-04-20 Pharmajet, Inc. Needle-less injector
US7842008B2 (en) * 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
TW200800223A (en) 2005-12-21 2008-01-01 Shire Pharmaceuticals Inc Transdermal delivery of meptazinol
US20100209483A1 (en) 2005-12-21 2010-08-19 Richard Franklin Transdermal delivery of meptazinol
ATE532553T1 (de) 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co Transdermales arzneiverabreichungsgerät mit mikronadeln
JP2007289482A (ja) * 2006-04-26 2007-11-08 Transcutaneous Technologies Inc 経皮投与装置
KR100886633B1 (ko) 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
EP2104525A4 (en) 2006-12-29 2010-12-29 Amir Genosar HYPODERMIC RESERVOIR AND APPARATUS FOR DRUG DELIVERY
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US8592640B2 (en) * 2009-08-11 2013-11-26 Neodyne Biosciences, Inc. Devices and methods for dressing applicators
US20100121307A1 (en) 2007-08-24 2010-05-13 Microfabrica Inc. Microneedles, Microneedle Arrays, Methods for Making, and Transdermal and/or Intradermal Applications
US7911480B2 (en) 2007-10-08 2011-03-22 Via Technologies, Inc. Compression of multiple-sample-anti-aliasing tile data in a graphics pipeline
CN201216811Y (zh) 2008-06-19 2009-04-08 陈青山 透皮给药微针阵列与软性成形面膜的集成结构
WO2009158477A1 (en) 2008-06-25 2009-12-30 Us Worldmeds Llc Skin patches and sustained-release formulations comprising lofexidine for transdermal and oral delivery
CN101745177A (zh) 2008-11-28 2010-06-23 上海百星药业有限公司 一次性使用并拥有自身动力的给药装置
RU85338U1 (ru) * 2009-02-24 2009-08-10 Государственное образовательное учреждение высшего профессионального образования "Курский государственный технический университет" Устройство для трансдермальной доставки лекарственных средств
KR101030752B1 (ko) * 2009-04-09 2011-04-26 한국생명공학연구원 유체전달을 조절할 수 있는 마이크로 니들 유닛
US8690838B2 (en) 2009-05-01 2014-04-08 Nanbu Plastics Co., Ltd. Transdermal administration device
CA2769102C (en) * 2009-07-31 2017-09-19 3M Innovative Properties Company Hollow microneedle arrays
DK2781228T3 (en) * 2009-12-16 2016-03-21 Becton Dickinson Co A device for self-injection
US20110172637A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172638A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US20110172645A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172609A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
JP5735773B2 (ja) * 2010-03-29 2015-06-17 シスメックス株式会社 生体成分分析方法及び生体成分分析装置
EP2566568B1 (en) 2010-05-04 2019-04-10 Corium International, Inc. Applicators for microneedles
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
CN102671291B (zh) * 2011-03-14 2014-07-30 中国人民解放军军事医学科学院毒物药物研究所 基于渗透压为动力的可控微输注装置
CN202173684U (zh) * 2011-08-26 2012-03-28 吴翠岗 一种微针美容仪
CN202590041U (zh) * 2012-05-21 2012-12-12 王金峰 注射局部皮肤拉紧器
CN202740542U (zh) * 2012-08-06 2013-02-20 安徽理工大学 无针注射器的辅助注射装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
CN1571685A (zh) * 2001-09-12 2005-01-26 贝克顿迪肯森公司 用于药物传送的微针为基础的笔装置和使用该装置的方法
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
CN101801452A (zh) * 2007-08-06 2010-08-11 宁静制药公司 用于去氨加压素药物给送的方法和设备
US20110288526A1 (en) * 2008-11-07 2011-11-24 Min Wei Pen Needle Assembly For Intradermal Injection
US20110022002A1 (en) * 2008-12-16 2011-01-27 Medtronic Minimed, Inc. Needle insertion systems and methods
CN102725019A (zh) * 2010-01-08 2012-10-10 威斯康星校友研究基金会 用于基于微针的药物递送设备的囊状装置

Also Published As

Publication number Publication date
CN109621083B (zh) 2022-03-22
JP6839223B2 (ja) 2021-03-03
CA2901568A1 (en) 2014-09-04
CA2901568C (en) 2021-02-16
AU2014222308A1 (en) 2015-09-24
BR112015020328B1 (pt) 2022-05-31
KR20220034913A (ko) 2022-03-18
CN105073179A (zh) 2015-11-18
RU2015138281A (ru) 2017-03-20
EP2961471A4 (en) 2017-04-05
US20210170153A1 (en) 2021-06-10
MX2015011071A (es) 2015-10-29
JP2019162444A (ja) 2019-09-26
US20190134369A1 (en) 2019-05-09
KR102571835B1 (ko) 2023-08-30
KR102295456B1 (ko) 2021-08-27
KR102370538B1 (ko) 2022-03-07
MX360121B (es) 2018-10-03
RU2622605C2 (ru) 2017-06-16
JP6522523B2 (ja) 2019-05-29
AU2014222308B2 (en) 2018-11-08
KR20210107180A (ko) 2021-08-31
BR112015020328A2 (pt) 2017-07-18
EP2961471A1 (en) 2016-01-06
US20150367117A1 (en) 2015-12-24
CN109621083A (zh) 2019-04-16
KR20150126617A (ko) 2015-11-12
WO2014132240A1 (en) 2014-09-04
EP2961471B1 (en) 2023-10-25
US10953211B2 (en) 2021-03-23
JP2016511679A (ja) 2016-04-21
US11883622B2 (en) 2024-01-30
US10183156B2 (en) 2019-01-22

Similar Documents

Publication Publication Date Title
CN105073179B (zh) 经皮药物递送装置
JP2022103381A (ja) 経皮的薬物送達装置および方法
US7115108B2 (en) Method and device for intradermally delivering a substance
KR20100016481A (ko) 마이크로 미세바늘 경피 전달 장치
KR20220110542A (ko) 마이크로니들을 갖는 유체 전달 기구
CN106535979A (zh) 透皮药物递送设备的控制器部分和方法
EP2961469A1 (en) Drug delivery device
CN106232171A (zh) 透皮药物递送设备的储盒部分和方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20190125

Address after: California, USA

Applicant after: Sorrento Therapeutics, Inc.

Address before: Wisconsin

Applicant before: Kimberly-Clark Worldwide, Inc.

TA01 Transfer of patent application right
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190319

CF01 Termination of patent right due to non-payment of annual fee