CN105056013A - Nursing medicine for treating child enterobiasis - Google Patents

Nursing medicine for treating child enterobiasis Download PDF

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Publication number
CN105056013A
CN105056013A CN201510546003.XA CN201510546003A CN105056013A CN 105056013 A CN105056013 A CN 105056013A CN 201510546003 A CN201510546003 A CN 201510546003A CN 105056013 A CN105056013 A CN 105056013A
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medicine
enterobiasis
nursing
fructus
nursing medicine
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陈红
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Abstract

The invention belongs to the technical field of medicine, and particularly relates to nursing medicine for treating the child enterobiasis. The nursing medicine comprises fruits of rangoon creepers, radix sophorae flavescentis, fructus cnidii, polygala tenuifolia, cortex dictamni, cortex dictamni, rhizoma atractylodis, codonopsis pilosula, hawthorns, malt and the like. The nursing medicine has the remarkable curative effects of killing parasites to relieve itching, tonifying the spleen, promoting appetite, clearing away heat and toxic materials, tranquilizing the mind and promoting the intelligence; the nursing medicine can serve as effective medicine for treating the enterobiasis, in particular to the enterobiasis with spleen and stomach weakness symptoms in a nursing mode.

Description

A kind of nursing medicine for the treatment of infantile oxyuriasis
Technical field
The invention belongs to medical art, be specifically related to a kind of nursing medicine for the treatment of infantile oxyuriasis.
Background technology
Enterobiasis is the common intestinal parasitical diseases caused by a kind of pinworm parasitism.Its ripe female worm occupy large intestine mostly, and head pierces intestinal mucosa and draws nutrition, can cause the tiny ulcer of intestinal wall, and pinworm heard night shifts to rectum, and climbs out of anus and lay eggs, and people is very itched unbearably.Enterobiasis clinical with anus, perineal position pruritus, sleep disorder and symptom of digestive tract to a certain degree for main manifestations, be more common in child, adult also can fall ill.Primary disease is early on the books in Ancient Times in China medical book, and ancient medicine thinks weakness of the spleen and stomach, biochemical weary source and cause internal organs weakness, then worm is easily taken advantage of a weak point, and is the primary pathogenic event of enterobiasis.The Ming Dynasty " Jing Yue's complete work parasites " is said " dirty strong arrogant person, with food with change, worm is deposited difficulty from difficulty and deposits, if visceral-qi is weak, rowization late, then stops to gather and gradually raw parasites ".The Qing Dynasty's " pediatrics releases mystery abdominal pain and distension " cloud " children's is originally timid, deficiency-cold of the stomach, and worm is dynamic and pained ".
General treatment and the upper infant of nursing must wear full crotch trousers, prevent finger contact anus, every morning with soap warm water cleaning skin around the rectum, the underwear pants changed should steaming and decocting or boiled water soak after Exposure to Sunlight parasite killing, continuous many days, treat with anthelmintic drug simultaneously.Western medicine effect still can, but there is relevant side effect or potential risk more.The Chinese medicine preparation that modern Chinese medicine utilizes advanced scientific research methods to prepare, the science and reliability for the treatment of enterobiasis are significantly improved, and have cure rate high, toxic and side effects is little, the advantage not easily recurred, the nursing Chinese medicine preparation of therefore profound under instruction of Chinese Medicine theory exploration treatment enterobiasis to be applied to clinical expansion necessary.
Summary of the invention
In order to solve the problem, the present invention aims to provide a kind of nursing Chinese medicine composition for the treatment of enterobiasis and preparation method thereof.
An object of the present invention is to provide a kind of nursing Chinese medicine composition for the treatment of enterobiasis.
Another object of the present invention is to provide a kind of preparation method for the treatment of the nursing Chinese medicine composition of enterobiasis.
The present invention treats the nursing Chinese medicine composition of enterobiasis, and its active ingredient is made up of the crude drug of following weight portion: Fructus Quisqualis 10-12g, Radix Sophorae Flavescentis 2-4g, Fructus Cnidii 6-8g, Radix Polygalae 4-6g, Cortex Dictamni 8-10g, Radix Scrophulariae 8-10g, Rhizoma Atractylodis 10-12g, Radix Codonopsis 3-5g, Fructus Crataegi 8-10g, Fructus Hordei Germinatus 6-8g.
Optimal technical scheme of the present invention is that Chinese medicine composition of the present invention is obtained by the crude drug of following weight portion: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g.
The nursing Chinese medicine composition that the present invention treats enterobiasis can also contain pharmaceutically acceptable carrier, is prepared into conventional formulation, as capsule, granule, tablet or oral liquid, is preferably granule.
The preparation method that the present invention treats the nursing Chinese medicine composition of enterobiasis comprises following steps: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, and be directly used as medicine use or 50 DEG C of cold drying, add appropriate amount of auxiliary materials through normal process steps after pulverizing and make clinical acceptable dosage form.
The present invention relatively and prior art, has following clear superiority:
Nursing medicament composing prescription of the present invention mainly develops according to the pathogenic characteristic of enterobiasis patient, Fructus Quisqualis in side, Radix Sophorae Flavescentis, Fructus Cnidii, heat clearing and damp drying, killing parasites for relieving itching; Cortex Dictamni, Radix Scrophulariae, clearing away heat and cooling blood, removing toxic substances of dispeling the wind; Rhizoma Atractylodis, Radix Codonopsis, drying damp and strengthening spleen, invigorating the spleen and replenishing QI; Fructus Crataegi, Fructus Hordei Germinatus, promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis; Radix Polygalae, Fructus Alpiniae Oxyphyllae of calming the nerves.All medicines share has killing parasites for relieving itching, spleen benefiting and stimulating the appetite, heat-clearing and toxic substances removing, the significant curative effect of Fructus Alpiniae Oxyphyllae of calming the nerves, and has extremely strong pertinent nursing effect to enterobiasis especially weakness of the spleen and the stomach diseases enterobiasis.Clinical observation finds, treatment group uses invention formulation treatment enterobiasis cure rate, effective percentage high, and be significantly better than matched group, safety is simultaneously high, side effect is little.
Further, in Chinese medicine composition of the present invention, the function of each crude drug and function cure mainly:
Fructus Quisqualis, sweet, temperature.Return spleen, stomach warp.Killing insect and eliminating accumulation.For ascarid, enterobiasis, abdominal pain due to worm stagnation, infantile malnutrition.
Radix Sophorae Flavescentis is bitter, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Fructus Cnidii, acrid, bitter, warm.Enter kidney, spleen channel.Warming the kidney to activate YANG, dispels the wind, dampness, parasite killing.Control impotence in male, scrotum pruritus due to damp pathogen, woman's leukorrhagia pudendal pruritus, cold uterus is infertile, rheumatic arthralgia, scabies eczema.
Radix Polygalae, bitter, pungent, warm.GUIXIN, kidney, lung meridian.To calm the nerves Fructus Alpiniae Oxyphyllae, eliminate the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Cortex Dictamni is bitter, cold.Return spleen, stomach, urinary bladder channel.Heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.
Radix Scrophulariae, sweet, bitter, salty, be slightly cold.Return lung, stomach, kidney channel.Removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Rhizoma Atractylodis, pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Radix Codonopsis, sweet, flat.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Fructus Crataegi, sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.
Fructus Hordei Germinatus, sweet, flat.Return spleen, stomach warp.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.Fructus Hordei Germinatus: invigorating the spleen and regulating the stomach, soothing the liver circulation of qi promoting.For insufficiency of the spleen lack of appetite, milk smoulders.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following specific embodiment.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
Embodiment 1 oral liquid
The each crude drug of the present invention is taken: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g by following weight portion.
Preparation technology is as follows: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, adds appropriate amount of auxiliary materials make oral liquid through normal process steps.
When using traditional Chinese medicine composition for treating enterobiasis of the present invention, take prepared oral liquid, every day twice, each one bottle, every bottle containing crude drug amount 1.0g.
Embodiment 2 granule
The each crude drug of the present invention is taken: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g by following weight portion.
Preparation technology is as follows:
Take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, and 50 DEG C of cold drying, add appropriate amount of auxiliary materials through normal process steps after pulverizing and make granule.
When using traditional Chinese medicine composition for treating enterobiasis of the present invention, take prepared granule, containing crude drug amount 1.0g, every day 2 times, each 1 bag, take half an hour after meal for every bag.
Embodiment 3 tablet
The each crude drug of the present invention is taken: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g by following weight portion.
Preparation technology is as follows: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, and 50 DEG C of cold drying, add appropriate amount of auxiliary materials through normal process steps after pulverizing and make tablet.
When using traditional Chinese medicine composition for treating enterobiasis of the present invention, take prepared tablet, every sheet is containing crude drug amount 0.3g, and every day 2 times, each 2-4 sheet, takes after meal half an hour.
Embodiment 4 capsule
The each crude drug of the present invention is taken: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g by following weight portion.
Preparation technology is as follows: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, and 50 DEG C of cold drying, add appropriate amount of auxiliary materials through normal process steps after pulverizing and make capsule.
When using traditional Chinese medicine composition for treating enterobiasis of the present invention, use prepared capsule, every contains crude drug amount 0.3g, and every day 2 times, each 2-4 grain, takes after meal half an hour.
Embodiment 5 oral liquid
The each crude drug of the present invention is taken: Fructus Quisqualis 10g, Radix Sophorae Flavescentis 2g, Fructus Cnidii 6g, Radix Polygalae 4g, Cortex Dictamni 8g, Radix Scrophulariae 8g, Rhizoma Atractylodis 10g, Radix Codonopsis 3g, Fructus Crataegi 8g, Fructus Hordei Germinatus 6g by following weight portion.
Preparation technology is as follows: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, adds appropriate amount of auxiliary materials make oral liquid through normal process steps.
When using traditional Chinese medicine composition for treating enterobiasis of the present invention, take prepared oral liquid, every day twice, each one bottle, every bottle containing crude drug amount 1.0g.
Embodiment 6 oral liquid
The each crude drug of the present invention is taken: Fructus Quisqualis 12g, Radix Sophorae Flavescentis 4g, Fructus Cnidii 8g, Radix Polygalae 6g, Cortex Dictamni 10g, Radix Scrophulariae 10g, Rhizoma Atractylodis 12g, Radix Codonopsis 5g, Fructus Crataegi 10g, Fructus Hordei Germinatus 8g by following weight portion.
Preparation technology is as follows: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, adds appropriate amount of auxiliary materials make oral liquid through normal process steps.When using traditional Chinese medicine composition for treating enterobiasis of the present invention, take prepared oral liquid, every day twice, each one bottle, every bottle containing crude drug amount 1.0g.
The nursing clinical observation of embodiment 6 traditional Chinese medicine composition for treating enterobiasis of the present invention
1, physical data:
60 routine infants all accord with enterobiasis diagnostic criteria in " the clinical handbook of newly organized TCM Pediatrics ", and Chinese medical discrimination meets due to weakness of spleen and stomach.Be divided into treatment group and matched group at random, in treatment group 30 example, man 17 example, female 13 example, 2 ~ 5 years old 14 example, 6 ~ 8 years old 16 example; In matched group 30 example, man 15 example. female 15 example, 2 ~ 5 years old 16 example, 6 ~ 8 years old 14 example; All infants all have the symptoms such as crissum in various degree or perineal position pruritus, bruxism, fingernail biting, uneasiness of crying and screaming, fright at night, appetite are low, stomachache.The physical data such as two groups of case ages, courses of disease, through statistical procedures there was no significant difference, have comparability.
2, diagnostic criteria:
In " the clinical handbook of newly organized TCM Pediatrics " to the clinical diagnosis of enterobiasis be: anus is very itched, and night increases the weight of, impact sleep; Children's is absent minded, irritated, easily shies, grinds one's teeth in sleep, locally dermatitis can occur, and pinworm intrusion adjacent organs leads to complications once in a while, as urinary tract infection, occurs frequent micturition, urgent micturition, dysurea, the enuresis etc.; Vaginitis, salpingitis, endometritis, the accidental abdominal cavity that enters causes peritonitis, and Fujian tail is scorching.The stimulation of pinworm to intestinal wall causes decreased food intake, feels sick, vomiting, stomachache, the symptoms such as diarrhoea.Auxiliary inspection Check: can find at its anus pleat or perineum place after children's falls asleep 1-3 hour and burn worm; Or early morning get up before be placed on crissum pleat place with a bit of hinge, flicking paper is to adhere to worm's ovum, and microscopy can find pinworm egg.
Syndrome Differentiation of Traditional Chinese Medicine due to weakness of spleen and stomach disease is seen: pruritus ani, abdominal part dull pain, and complexion beach wormwood is yellow, emaciated physique, indigestion and loss of appetite lack of appetite, abdominal distention after meal, loose stool, fatigue and asthenia, and pale tongue with thin fur is white, thready and weak pulse.
3, Therapeutic Method:
Matched group: oral piperazine citrate sheet, each 30mg/kg/ time, 2 times on the one, daily dose more than 2g, must not be used in conjunction 5 ~ 7 days.
Treatment group: take oral liquid prepared by embodiment 1, every day twice, each one bottle, every bottle, containing crude drug amount 1.0g, is used in conjunction 5 ~ 7 days.
Be eczema sample shower for the rotten to the corn sepage of perianal infection during nursing for treating, be separately applied to crissum with 10% sulfur ointment.
The urine smell of patient's diet, pungent, stimulating food; Trousers should be loose, and keep dry and comfortable, pruritus should not be scratched; Every morning cleans skin around the rectum with soap warm water, and the underwear pants changed should steaming and decocting or the rear Exposure to Sunlight parasite killing of boiled water immersion.
4, the standard of curative effect evaluation:
Cure: transference cure, continuous 3 hinge anuses are wiped method mirror and are picked up and do not find worm's ovum;
Take a turn for the better: symptom is improved, and microscopy can find worm's ovum;
Invalid: symptom is without improvement, and microscopy finds worm's ovum.
Total effective rate=cure rate+obvious effective rate.
5, clinical effectiveness:
In clinical observation process, without coming off, exiting case, 60 routine patients all complete clinical observation.After 7 days, two groups of clinical effectiveness compare, treatment group clinical cure 14 example, improvement rate 15 example, total effective rate 96.7%, and clinical effectiveness is remarkable; Matched group clinical cure 8 example, take a turn for the better 10 examples, total effective rate 60.0%.Two groups of therapeutic outcomes compare, and treatment group is significantly better than matched group, and especially treatment group clinical effectiveness in cure rate aspect is more remarkable.Concrete outcome sees the following form.
A table 1. liang group clinical effectiveness compares
Group n Cure Take a turn for the better Invalid Total effective rate
Treatment group 30 14 15 1 96.7%
Matched group 30 8 10 12 60.0%
Result display after above-mentioned clinical observation, use the present invention to nurse with Drug therapy enterobiasis especially weakness of the spleen and the stomach diseases enterobiasis, determined curative effect, cure rate is high, and therapeutic effect is significantly better than matched group.Do not find side effect after treatment group medication simultaneously, after matched group medication, occur 1 example of feeling sick, dizzy 2 examples, transference cure after drug withdrawal, illustrate that drug safety of the present invention is also fine, can, as the choice drug for the treatment of enterobiasis particularly weakness of the spleen and the stomach diseases enterobiasis, be worth promoting the use of clinically.

Claims (7)

1. treat a nursing medicine for infantile oxyuriasis, it is characterized in that, the composition and ratio of its crude drug is: Fructus Quisqualis 10-12g, Radix Sophorae Flavescentis 2-4g, Fructus Cnidii 6-8g, Radix Polygalae 4-6g, Cortex Dictamni 8-10g, Radix Scrophulariae 8-10g, Rhizoma Atractylodis 10-12g, Radix Codonopsis 3-5g, Fructus Crataegi 8-10g, Fructus Hordei Germinatus 6-8g.
2. nursing medicine as claimed in claim 1, it is characterized in that, the composition and ratio of its crude drug is: Fructus Quisqualis 11g, Radix Sophorae Flavescentis 3g, Fructus Cnidii 7g, Radix Polygalae 5g, Cortex Dictamni 9g, Radix Scrophulariae 9g, Rhizoma Atractylodis 11g, Radix Codonopsis 4g, Fructus Crataegi 9g, Fructus Hordei Germinatus 7g.
3. the nursing medicine as described in claim 1 or 2, is characterized in that, described Chinese medicine composition is capsule, granule, tablet or oral liquid.
4. the nursing medicine as described in claim 1 or 2, is characterized in that, described Chinese medicine composition is preferably oral liquid.
5. a kind of nursing medicine for the treatment of infantile oxyuriasis as described in claim 1,2, it is characterized in that, the preparation method of described pharmaceutical composition comprises following steps: take each Chinese medicine component according to aforesaid ratio and be ground into coarse powder respectively; Each decoction adds water 4 times amount, decocts secondary, each 2 hours, collecting decoction, filters; When filtrate is concentrated into 65 DEG C, relative density is the clear paste of 1.10 ~ 1.15, and be directly used as medicine use or 50 DEG C of cold drying, add appropriate amount of auxiliary materials through normal process steps after pulverizing and make clinical acceptable dosage form.
6. the purposes of the nursing medicine as described in claim 1,2 in the nursing medicine of preparation treatment enterobiasis.
7. the purposes of the nursing medicine as described in claim 1,2 in the nursing medicine of preparation treatment weakness of the spleen and the stomach diseases enterobiasis.
CN201510546003.XA 2015-08-30 2015-08-30 Nursing medicine for treating child enterobiasis Pending CN105056013A (en)

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Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2008039362A2 (en) * 2006-09-25 2008-04-03 Haas, John, I. Methods for treating or preventing infestation
CN103417883A (en) * 2013-08-06 2013-12-04 天津太平洋制药有限公司 Medicine for treating pinworm

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008039362A2 (en) * 2006-09-25 2008-04-03 Haas, John, I. Methods for treating or preventing infestation
CN103417883A (en) * 2013-08-06 2013-12-04 天津太平洋制药有限公司 Medicine for treating pinworm

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Application publication date: 20151118