CN105055859B - A kind of method of preparation and use preventing and treating livestock and birds respiratory disease complexing agent - Google Patents

A kind of method of preparation and use preventing and treating livestock and birds respiratory disease complexing agent Download PDF

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CN105055859B
CN105055859B CN201510512359.1A CN201510512359A CN105055859B CN 105055859 B CN105055859 B CN 105055859B CN 201510512359 A CN201510512359 A CN 201510512359A CN 105055859 B CN105055859 B CN 105055859B
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complexing agent
preparation
radix
parts
respiratory disease
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CN105055859A (en
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蔡冠川
曾勤琇
战晓秀
邵妮
陈贵华
仇宇虹
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Qingdao Zhongnong Huashang Biological Engineering Co Ltd
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Qingdao Zhongnong Huashang Biological Engineering Co Ltd
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    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

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Abstract

The invention discloses a kind of methods of preparation and use for preventing and treating livestock and birds respiratory disease complexing agent, extract processing by raw material of Chinese medicine preparation, obtain Chinese medicine extract;By vitaminAD3It is oily to be mixed with the Chinese medicine extract, carry out the preparation of complexing agent;The Chinese medicine preparation includes following component: Radix Polygalae, sea-buckthorn, Cortex Magnoliae Officinalis, Fructus Aurantii, rhizoma atractylodis, perilla leaf, radix polygonati officinalis, Radix Ophiopogonis, lily, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, Radix Glycyrrhizae, honeysuckle, the raw materials used in the present invention resources of Chinese medicinal herb is extensive, at low cost, complexing agent cure rate is high for this, drug noresidue, has no toxic side effect, and for prevention and treatment livestock and birds respiratory disease, bone growth, raising immunity, resistance, survival rate is promoted to have obvious action.

Description

A kind of method of preparation and use preventing and treating livestock and birds respiratory disease complexing agent
Technical field
The invention belongs to field of veterinary, especially a kind of preparation for preventing and treating livestock and birds respiratory disease complexing agent and user Method.
Background technique
With the diversification of aggravation and the user demand of market competition, the large-scale cultivation of the livestock and poultry such as chicken, duck, pig, ox is Through becoming trend.Under large-scale cultivation mode, livestock and poultry group's density is big, and transmission is fast, and it is even dead to easily cause livestock and poultry morbidity It dies, wherein livestock and birds respiratory disease has become that livestock and poultry farm is universal and one of serious disease.
Livestock and birds respiratory disease treatment difficulty is big, is easy recurrence, and to cultivation, dealer brings great economic loss.Livestock and poultry exhale The primary sexual factor for inhaling tract disease is some bacteriums, mycoplasma, virus, after infecting livestock and poultry, causes livestock and poultry for a long time or intermittence Cough, shed tears, flow nose liquid, cause livestock and poultry stress and immunity degradation, and influence livestock and poultry meat and additional performance.
Currently, the primary treatment scheme of reply livestock and birds respiratory disease is the treatment of antibiotic or antibacterials, from control Pathogen angle is started with, and the disappearance from medication to livestock and poultry respiratory symptom probably needs 3-5 days.Cough, shed tears in during this period, The respiratory symptoms such as stream nose liquid still can perplex livestock and poultry group, persistently bring economic loss, and disease is not easy to cure.
Therefore currently, the research of livestock and birds respiratory disease is especially the absence of one kind also in the exploratory stage at initial stage The preparation of livestock and birds respiratory disease is effectively prevented, this causes very big difficulty to the prevention and treatment of livestock and birds respiratory disease.
Summary of the invention
To solve the above problems, the present invention provides a kind of preparation for preventing and treating livestock and birds respiratory disease complexing agent and users Method.
The invention provides the following technical scheme:
A kind of preparation method preventing and treating livestock and birds respiratory disease complexing agent, includes the following steps:
Step 1: processing is extracted by raw material of Chinese medicine preparation, obtains Chinese medicine extract;
Step 2: by vitaminAD3It is oily to be mixed with the Chinese medicine extract, carry out the preparation of complexing agent;
The Chinese medicine preparation includes following component: Radix Polygalae, sea-buckthorn, Cortex Magnoliae Officinalis, Fructus Aurantii, rhizoma atractylodis, perilla leaf, radix polygonati officinalis, Radix Ophiopogonis, hundred Conjunction, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, Radix Glycyrrhizae, honeysuckle.
As preferred embodiment therein, the Chinese medicine preparation includes following mass fraction formula components:
30~50 parts of Radix Polygalae, 40~60 parts of sea-buckthorn, 90~110 parts of Cortex Magnoliae Officinalis, 80~100 parts of Fructus Aurantii, 50~70 parts of rhizoma atractylodis, purple 60~80 parts of perilla leaf, 100~120 parts of radix polygonati officinalis, 70~90 parts of Radix Ophiopogonis, 60~80 parts of lily, 100~120 parts of mulberry leaf, the root bark of white mulberry 90 ~110 parts, 80~100 parts of Radix Codonopsis, 40~60 parts of Radix Glycyrrhizae, 40~60 parts of honeysuckle.
Further, it in step 1, sequentially includes the following steps:
S1: Radix Polygalae, sea-buckthorn, Cortex Magnoliae Officinalis, Fructus Aurantii are added to 60% ethyl alcohol, be heated to reflux 3 times, after phegma is merged It filters spare;
S2: distillate is collected after adding water to distill rhizoma atractylodis, perilla leaf, distillate is filtered spare;
S3: radix polygonati officinalis, Radix Ophiopogonis, lily, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, Radix Glycyrrhizae, eight taste medicine of honeysuckle add water to cook, and obtain Extracting solution, and concentration is carried out to extracting solution, obtain concentrate;
S4: the concentrate obtained in step S3 is merged with the phegma in step S1, further progress concentration obtains To concentration liquid;
S5: the distillate obtained in the concentration liquid obtained in step S4 and step S2 is merged, traditional Chinese medicine extraction is obtained Liquid.
Further, in step S3,
By radix polygonati officinalis, Radix Ophiopogonis, lily, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, seven taste Chinese medicine of Radix Glycyrrhizae and water example 1:6 formulation in mass ratio After liquid, first temperature leaching 0.5~1 hour, reheating makes feed liquid to boiling, and then small fire decocts 1~1.5 hour, is subsequently added into honeysuckle, Continue decoction 0.5~1 hour, finally extract decoction liquor, is filtered with 120 mesh filters, obtain extracting solution;
After extracting solution is taken only, 4 times of amounts of water to net medicinal material are added, carry out secondary decoction: heating makes feed liquid to boiling, small Fire decocts 1~1.5 hour, extracts decoction liquor, is filtered with 120 mesh filters, obtains extracting solution;
After extracting solution is taken only, 4 times of amounts of water to net medicinal material are added, decocted three times: heating makes feed liquid to boiling, small Fire decocts 1~1.5 hour, extracts decoction liquor, is filtered with 120 mesh filters, obtains extracting solution.
Further, in step S3:
It is -0.07MPa that extracting solution, which is drawn into vacuum degree, and temperature is in 70 DEG C of environment, being evaporated to relative density is 95% ethyl alcohol is added in 1.10-1.20, and concentration of alcohol is made to be down to 60%, stirs 10~20 minutes, stands in cooling water environment 12~18 hours, obtain concentrate.
Further, in step S4:
The supernatant of concentrate is merged with the phegma in step S1, is -0.075MPa in vacuum degree, temperature is 60 DEG C Environment in, be evaporated to relative density be 1.10-1.20, obtain concentration liquid.
Further, in step 2:
VitaminAD is added into Chinese medicine extract3Oil, containing 3-Hydroxyretinol 50~9,000,000 IU/1300-3300mg, dimension life Plain D385~2,400,000 IU/21-60mg are 4.0-4.5 with hydrochloric acid tune PH, stand 15~20 minutes, and filtering, filtrate passes through 0.45um filter, it is filling to obtain the final product.
The present invention provides a kind of application method for preventing and treating livestock and birds respiratory disease complexing agent, and the complexing agent is trained for laying hen It educates:
Laying hen just goes out within shell 24 hours, adds water 1000ML to dilute 0.2~0.4ML complexing agent, guarantees 200 chick 2- It freely drinks and finishes in 3 hours, twice a day;After chick in one week opens food, while being fed with chick material, by 0.3~0.5ML Complexing agent adds water 1000ML to dilute, and guarantees freely to drink in 200 chick 2-3 hours and finishes, twice a day;2-15 weeks chick While feeding with big grain chick material, adds water 1000ML to dilute 0.5~0.8ML complexing agent, guarantee 200 chick 2-3 hours Interior freely drink finishes, twice a day;0.8~1.2ML complexing agent is added water 1000ML to dilute, guaranteed by 15-18 weeks chicken It freely drinks in chicken 2-3 hours for 200 and finishes, twice a day;19th week later at chicken, and 1.5~2ML complexing agent is added water 1000ML dilution guarantees that 200 finish at freely drinking in chicken 2-3 hours, twice a day.
The present invention provides the application method of another prevention and treatment livestock and birds respiratory disease complexing agent, and the complexing agent is used for broiler chicken It cultivates:
Broiler chicken, which has just gone out within shell 24 hours, adds water 1000ML to dilute 0.2~0.4ML complexing agent, guarantees 200 chick 2-3 It freely drinks and finishes in hour, twice a day;After the chick of 1-10 age in days opens food, while being fed with chick material, by 0.3~ 0.5ML complexing agent adds water 1000ML to dilute, and guarantees freely to drink in 200 chick 2-3 hours and finishes, twice a day;20-30 days 1~2ML complexing agent is added water 1000ML to dilute, guarantees freely to drink in 200 broiler chicken 2-3 hours and finish by the broiler chicken in age, and one day Twice;2~3ML complexing agent is added water 1000ML to dilute, guarantees freely to drink in 200 broiler chicken 2-3 hours by the broiler chicken after 30 ages in days With finishing, twice a day.
In addition, the present invention also provides the application method of another prevention and treatment livestock and birds respiratory disease complexing agent, the complexing agent It is cultivated for boar:
25~35ML complexing agent is added water 1000ML to dilute by the piglet stage, guarantees freely to have drunk in piglet 2-3 hours Finish, twice a day;At the pig stage, add water 1000ML to dilute 35~45ML complexing agent, guarantees at freely being drunk in pig 2-3 hours It finishes, twice a day;45~55ML complexing agent is added water 1000ML to dilute by the boar stage, guarantees freely to drink in boar 2-3 hours With finishing, twice a day.
Beneficial effects of the present invention are as follows:
1, the raw materials used in the present invention resources of Chinese medicinal herb is extensive, at low cost;
2, complexing agent cure rate is high, drug noresidue, has no toxic side effect, and has for prevention and treatment livestock and birds respiratory disease aobvious The effect of work;
3, inventive formulation science, has the effect of with cough-relieving, relievings asthma, eliminating the phlegm, preparation is liquid, easy to use;
4, present invention addition vitaminAD3Oily composition also has the function of promoting livestock and poultry bone growth, it is attached to improve livestock and poultry It is value added.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
Embodiment one:
A kind of preparation method preventing and treating livestock and birds respiratory disease complexing agent, includes the following steps:
It stocks up by following Chinese medicine preparation: Radix Polygalae 30g, sea-buckthorn 40g, Cortex Magnoliae Officinalis 90g, Fructus Aurantii 80g, rhizoma atractylodis 50g, perilla leaf 60g, radix polygonati officinalis 100g, Radix Ophiopogonis 70g, lily 60g, mulberry leaf 100g, root bark of white mulberry 90g, Radix Codonopsis 80g, Radix Glycyrrhizae 40g, honeysuckle 40g.
VitaminAD used in the present embodiment3Oil contains 500,000 IU/1300mg of 3-Hydroxyretinol, vitamin D3850000 IU/21mg.
60% ethyl alcohol is added to be heated to reflux 3 with Radix Polygalae 30g, sea-buckthorn 40g, Cortex Magnoliae Officinalis 90g, the Fructus Aurantii 80g in above-mentioned Chinese medicine preparation Secondary, 2 hours for the first time, second third time each 1 hour, filter liquor merged spare.
Rhizoma atractylodis, perilla leaf add water distillation to collect distillate, and distillate filtering is spare.
Remaining 8 taste medicines, except honeysuckle, radix polygonati officinalis 100g, Radix Ophiopogonis 70g, lily 60g, mulberry leaf 100g, root bark of white mulberry 90g, Radix Codonopsis 80g, Radix Glycyrrhizae 40g are put into extraction tank, and add water to the amount of 6 times of net medicinal material, temperature leaching 1 hour, and heating makes feed liquid to boiling, and small fire decocts 1.5 hours, honeysuckle is added, continues to decoct 0.5 hour, extracts decoction liquor, filtered by 120 mesh filters into fluid reservoir, Obtain extracting solution;
After extracting solution is taken only, 4 times of amounts of water to net medicinal material are added, heating makes feed liquid to boiling, second of small fire decoction 1 Hour, decoction liquor is extracted, is filtered by 120 mesh filters into fluid reservoir, obtains extracting solution;Third time decocts and second of phase Together.
It is -0.07MPa that extracting solution, which is drawn into vacuum degree, from fluid reservoir, is carried out in the inspissator that temperature is 70 DEG C dense Contracting, by outer circulation cold boiler, being evaporated to relative density is 1.10-1.20 (surveying at 68-72 DEG C), by concentrate pump Enter Alcohol-settling tank, 95% ethyl alcohol is added, concentration of alcohol is made to be down to 60%, stir 10 minutes, it is small that unlatching cooling water is allowed to rest for 12 When.
The supernatant of concentrate is evacuated in ethyl alcohol inspissator, is merged with the phegma of four medicines such as Radix Polygalae, Cortex Magnoliae Officinalis, true Reciprocal of duty cycle is -0.075MPa, and when temperature is 60 DEG C, by ethyl alcohol cold boiler, being evaporated to relative density is 1.10-1.20 (60 DEG C when survey), obtain concentration liquid, valve closed, after concentration liquid is extracted into weighing area, with rhizoma atractylodis and perilla leaf distillate Merge.
VitaminAD is added3Oil is 4.0-4.5 with hydrochloric acid tune PH, stands 15 minutes, filtering, and filtrate passes through 0.45um essence Close filter, it is filling to obtain the final product.
Embodiment two:
A kind of preparation method preventing and treating livestock and birds respiratory disease complexing agent, includes the following steps:
It stocks up by following Chinese medicine preparation: Radix Polygalae 40g, sea-buckthorn 50g, Cortex Magnoliae Officinalis 100g, Fructus Aurantii 90g, rhizoma atractylodis 60g, purple perilla Leaf 70, radix polygonati officinalis 110g, Radix Ophiopogonis 80g, lily 70g, mulberry leaf 110g, root bark of white mulberry 100g, Radix Codonopsis 90g, Radix Glycyrrhizae 50g, honeysuckle 50g.
VitaminAD used in the present embodiment3Oil contains 6,250,000 IU/2300mg of vitamin A, vitamin D31620000 IU/ 40mg。
The preparation of complexing agent is carried out by above-mentioned formula.
Embodiment three:
A kind of preparation method preventing and treating livestock and birds respiratory disease complexing agent, includes the following steps:
It stocks up by following Chinese medicine preparation: Radix Polygalae 50g, sea-buckthorn 60g, Cortex Magnoliae Officinalis 110g, Fructus Aurantii 100g, rhizoma atractylodis 70g, purple perilla Leaf 80, radix polygonati officinalis 120g, Radix Ophiopogonis 90g, lily 80g, mulberry leaf 120g, root bark of white mulberry 110g, Radix Codonopsis 100g, Radix Glycyrrhizae 600g, honeysuckle 60g。
VitaminAD used in the present embodiment3Oil contains 9,000,000 IU/3300mg of vitamin A, vitamin D32400000 IU/ 60mg。
The preparation of complexing agent is carried out by above-mentioned formula.
Comparative experiments one:
It is cultivated using a kind of prevention and treatment livestock and birds respiratory disease complexing agent of the embodiment of the present invention one for laying hen:
Qingdao chicken farm, winter, respiratory disease high-incidence time.It chooses 200 and just goes out shell layer chickens, growing each stage takes the photograph Enter complexing agent of the invention, another 200 have just gone out shell layer chicken and grown naturally, do not take in complexing agent of the invention.The use of complexing agent Process is as follows:
Laying hen, which has just gone out within shell 24 hours, adds water 1000ML to dilute 0.2ML complexing agent, guarantees in 200 chick 3 hours It drinks and finishes, twice a day;After Laying chicks in one week open food, while being fed with chick material, 0.3ML complexing agent is added into water 1000ML dilution, guarantees freely to drink in 200 chick 2.5 hours and finishes, twice a day;2-15 weeks chick is with big grain chick While material feeding, adds water 1000ML to dilute 0.6ML complexing agent, guarantee freely to drink in 200 chick 3 hours and finish, one Day is twice;1.2ML complexing agent is added water 1000ML to dilute, guarantees freely to drink in 200 chickens 2 hours by 15-18 weeks chicken It finishes, twice a day;19th week is later at chicken, adds water 1000ML to dilute 1.5ML complexing agent, guarantee 200 at chicken 3 hours Interior freely drink finishes, twice a day.
The chicken group for not taking in complexing agent of the present invention, occurs the diseased chicken of cough, asthma on the 14th, cough occurs in jumpbogroup when 16 age in days It coughs, shed tears, flowing the symptoms such as nose liquid, and having fragmentary death.It is respiratory disease through clinical diagnosis.
The chicken group for taking in complexing agent of the present invention, does not occur symptoms of respiratory disease.
Chicken group's isolation of respiratory disease will be infected, complexing agent of the invention is taken in by its growth phase, after 1 day, cough Etc. symptoms mitigate.After 3 days, situation takes a turn for the better, and a small amount of there are also the respiratory symptoms such as cough, stream nose liquid.After 7 days, Ji Qun each side planar State restores normal.
The chicken group of complexing agent of the present invention is not taken in after 19 weeks, 1.3 kilograms of average weight, takes in the chicken group of complexing agent of the present invention After 19 weeks, 1.6 kilograms of average weight, physique is very large, and bone is healthy and strong.
Comparative experiments two:
It is cultivated using a kind of prevention and treatment livestock and birds respiratory disease complexing agent of the embodiment of the present invention two for laying hen:
Qingdao chicken farm, winter, respiratory disease high-incidence time.It chooses 200 and just goes out shell broiler chicken, growing each stage takes the photograph Enter complexing agent of the invention, another 200 have just gone out shell broiler chicken and grown naturally, do not take in complexing agent of the invention.The use of complexing agent Process is as follows:
Broiler chicken, which has just gone out within shell 24 hours, adds water 1000ML to dilute 0.3ML complexing agent, guarantees in 200 chick 3 hours It drinks and finishes, twice a day;After the broiler chicks of 1-10 age in days open food, while being fed with chick material, 0.4ML complexing agent is added into water 1000ML dilution, guarantees freely to drink in 200 chick 2.5 hours and finishes, twice a day;The broiler chicken of 20-30 age in days, will 1.5ML complexing agent adds water 1000ML to dilute, and guarantees freely to drink in 200 broiler chicken 2 hours and finishes, twice a day;After 30 ages in days Broiler chicken, add water 1000ML to dilute 3ML complexing agent, guarantee freely to drink in 200 broiler chicken 3 hours and finish, twice a day.
The chicken group for not taking in complexing agent of the present invention, occurs the diseased chicken of cough, asthma on the 15th, cough occurs in jumpbogroup when 17 age in days It coughs, shed tears, flowing the symptoms such as nose liquid.It is respiratory disease through clinical diagnosis.
The chicken group for taking in complexing agent of the present invention, does not occur symptoms of respiratory disease.
Chicken group's isolation of respiratory disease will be infected, complexing agent of the invention is taken in by its growth phase, after 1 day, cough Etc. symptoms mitigate.After 3 days, situation takes a turn for the better, and a small amount of there are also the respiratory symptoms such as cough, stream nose liquid.After 7 days, Ji Qun each side planar State restores normal.
The chicken group of complexing agent of the present invention is not taken in after 19 weeks, 1.4 kilograms of average weight, takes in the chicken group of complexing agent of the present invention After 19 weeks, 1.6 kilograms of average weight, physique is very large, and bone is healthy and strong.
Comparative experiments three:
It is cultivated using a kind of prevention and treatment livestock and birds respiratory disease complexing agent of the embodiment of the present invention three for laying hen:
Pingdu pig farm, winter, respiratory disease high-incidence time.1 just birth piglet is chosen, each stage intake is grown Complexing agent of the invention, another 1 piglet that has just been born grow naturally, do not take in complexing agent of the invention.The use process of complexing agent It is as follows:
30ML complexing agent is added water 1000ML to dilute by the piglet stage, and guarantee is freely drunk in 2 hours and finished, twice a day; At the pig stage, water 1000ML is added to dilute 40ML complexing agent, guarantee is freely drunk in 2.5 hours and finished, twice a day;Boar rank 50ML complexing agent is added water 1000ML to dilute by section, and guarantee is freely drunk in 3 hours and finished, twice a day.
The swinery of complexing agent of the present invention is not taken in, and the cough of appearance on the 20th in piglet stage, asthma symptom are through clinical diagnosis Mild respiratory disease.
The piglet of complexing agent of the present invention is taken in, generation phase does not occur symptoms of respiratory disease.
The piglet of respiratory disease will be infected, complexing agent of the invention is taken in by its growth phase, after 3 days, situation takes a turn for the better, The respiratory symptoms such as cough, stream nose liquid mitigate, and after 7 days, piglet each side surface state restores normal.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (6)

1. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent, characterized by the following steps:
Step 1: processing is extracted by raw material of Chinese medicine preparation, obtains Chinese medicine extract;
Step 2: by vitaminAD3It is oily to be mixed with the Chinese medicine extract, carry out the preparation of complexing agent;
The Chinese medicine preparation is made of following mass fraction formula components:
30~50 parts of Radix Polygalae, 40~60 parts of sea-buckthorn, 90~110 parts of Cortex Magnoliae Officinalis, 80~100 parts of Fructus Aurantii, 50~70 parts of rhizoma atractylodis, perilla leaf 60~80 parts, 100~120 parts of radix polygonati officinalis, 70~90 parts of Radix Ophiopogonis, 60~80 parts of lily, 100~120 parts of mulberry leaf, the root bark of white mulberry 90~ 110 parts, 80~100 parts of Radix Codonopsis, 40~60 parts of Radix Glycyrrhizae, 40~60 parts of honeysuckle.
2. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent according to claim 1, it is characterised in that: step In rapid one, sequentially include the following steps:
S1: Radix Polygalae, sea-buckthorn, Cortex Magnoliae Officinalis, Fructus Aurantii are added to 60% ethyl alcohol, be heated to reflux 3 times, is filtered after phegma is merged It is spare;
S2: distillate is collected after adding water to distill rhizoma atractylodis, perilla leaf, distillate is filtered spare;
S3: radix polygonati officinalis, Radix Ophiopogonis, lily, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, Radix Glycyrrhizae, eight taste medicine of honeysuckle add water to cook, and obtain and extract Liquid, and concentration is carried out to extracting solution, obtain concentrate;
S4: the concentrate obtained in step S3 is merged with the phegma in step S1, further progress concentration obtains dense Contracting treatment fluid;
S5: the distillate obtained in the concentration liquid obtained in step S4 and step S2 is merged, Chinese medicine extract is obtained.
3. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent according to claim 2, it is characterised in that: step In rapid S3,
By radix polygonati officinalis, Radix Ophiopogonis, lily, mulberry leaf, the root bark of white mulberry, Radix Codonopsis, seven taste Chinese medicine of Radix Glycyrrhizae and water example 1:6 preparation liquid in mass ratio Afterwards, first temperature leaching 0.5~1 hour, reheating make feed liquid to boiling, and then small fire decocts 1~1.5 hour, are subsequently added into honeysuckle, after It is continuous to decoct 0.5-1 hours, decoction liquor is finally extracted, is filtered with 120 mesh filters, obtains extracting solution;
After extracting solution is taken only, add 4 times of amounts of water to net medicinal material, carry out secondary decoction: heating makes feed liquid to boiling, and small fire is pan-fried It boils 1-1.5 hours, extracts decoction liquor, filtered with 120 mesh filters, obtain extracting solution;
After extracting solution is taken only, add 4 times of amounts of water to net medicinal material, decocted three times: heating makes feed liquid to boiling, and small fire is pan-fried It boils 1-1.5 hours, extracts decoction liquor, filtered with 120 mesh filters, obtain extracting solution.
4. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent according to claim 3, it is characterised in that: step In rapid S3:
It is -0.07MPa that extracting solution, which is drawn into vacuum degree, and temperature is 1.10- in 70 DEG C of environment, to be evaporated to relative density 1.20,95% ethyl alcohol is added, concentration of alcohol is made to be down to 60%, stirs 10~20 minutes, stand 12 in cooling water environment~ 18 hours, obtain concentrate.
5. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent according to claim 4, it is characterised in that: step In rapid S4:
The supernatant of concentrate is merged with the phegma in step S1, is -0.075MPa, the ring that temperature is 60 DEG C in vacuum degree In border, being evaporated to relative density is 1.10-1.20, obtains concentration liquid.
6. a kind of preparation method for preventing and treating livestock and birds respiratory disease complexing agent according to claim 5, it is characterised in that: step In rapid two:
VitaminAD is added into Chinese medicine extract3Oil mixes, and is 4.0-4.5 with hydrochloric acid tune PH, stands 15~20 minutes, filtering, Filtrate by 0.45um filter, it is filling to obtain the final product.
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CN103120267A (en) * 2013-02-28 2013-05-29 灵山县园丰牧业有限公司 Feed for lingshan patridge chicken
CN103445029A (en) * 2013-09-21 2013-12-18 广南(湛江)家丰饲料有限公司 Pig feed additive capable of effectively preventing and treating respiratory diseases as well as improving immunity
CN104027442A (en) * 2014-05-24 2014-09-10 潍坊市富言畜禽病诊疗中心 Traditional Chinese medicine preparation adopted in green and residual medicine free broiler cultivation, preparation method thereof and method for cultivating broilers by using traditional Chinese medicine preparation

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