CN105055859A - Preparation and application methods for complex agent for preventing and treating respiratory disease of livestock - Google Patents
Preparation and application methods for complex agent for preventing and treating respiratory disease of livestock Download PDFInfo
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- CN105055859A CN105055859A CN201510512359.1A CN201510512359A CN105055859A CN 105055859 A CN105055859 A CN 105055859A CN 201510512359 A CN201510512359 A CN 201510512359A CN 105055859 A CN105055859 A CN 105055859A
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Abstract
The invention discloses preparation and application methods for a complex agent for preventing and treating the respiratory disease of livestock. The preparation method comprises the following steps: with a traditional Chinese medicine composition as raw material, extracting so as to obtain a traditional Chinese medicine extracting solution; mixing vitamin AD3 oil with the traditional Chinese medicine extracting solution and preparing the complex agent, wherein the traditional Chinese medicine composition comprises thinleaf milkwort root-bark, hippophae rhamnoides, cortex magnoliae officinalis, fructus aurantii, rhizoma atractylodis, perilla leaf, fragrant solomonseal rhizome, radix ophiopogonis, lily, folium mori, white mulberry root-bark, codonopsis pilosula, liquorice and honeysuckle. The used Chinese herbal medicines used as raw materials are wide in source, and low in cost; the complex agent is high in cure rate, has no drug residue, and no toxic or side effects, and has an obvious effect on preventing and treating the respiratory disease of livestock, promoting bone growth, improving immunity and resistance and increasing the survival rate.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of method of preparation and use of preventing and treating livestock and birds respiratory disease complexing agent.
Background technology
Along with the aggravation of the market competition and the variation of user's request, the large-scale cultivation of the poultry such as chicken, duck, pig, cattle becomes trend.Under large-scale cultivation pattern, poultry population density is large, and pathophoresis is fast, and easily cause poultry to fall ill even dead, wherein, livestock and birds respiratory disease has become one of general and serious disease of livestock and poultry farm.
Livestock and birds respiratory disease treatment difficulty is large, easily recurs, and brings great economic loss to cultivation dealer.The constitutional factor of livestock and birds respiratory disease is some antibacterials, mycoplasma, virus, after infecting poultry, cause the cough of the long-time or intermittence of poultry, shed tears, flow nose liquid, cause poultry stress and immunity degradation, and affect the meat of poultry and additional performance.
At present, the primary treatment scheme of reply livestock and birds respiratory disease is the treatment of antibiotic or antibacterials, and start with from control pathogen angle, the disappearance from medication to livestock and poultry respiratory symptom probably needs 3-5 days.Cough during this period, shed tears, flow the respiratory symptoms such as nose liquid and still can perplex poultry group, continue the loss brought economically, and disease is not easy healing.
Therefore at present, the research of livestock and birds respiratory disease is also in the exploratory stage at initial stage, especially lack a kind of preparation of effective control livestock and birds respiratory disease, this causes very large difficulty to the prevention and therapy of livestock and birds respiratory disease.
Summary of the invention
For solving the problem, the invention provides a kind of method of preparation and use of preventing and treating livestock and birds respiratory disease complexing agent.
The invention provides following technical scheme:
Prevent and treat a preparation method for livestock and birds respiratory disease complexing agent, comprise the steps:
Step one: be that raw material carries out extraction process with Chinese medicine formula, obtain Chinese medicine extraction liquid;
Step 2: by vitamin AD
3oily and described Chinese medicine extraction liquid mixes, and carries out the preparation of complexing agent;
Described Chinese medicine formula comprises following composition: Radix Polygalae, Fructus Hippophae, Cortex Magnoliae Officinalis, Fructus Aurantii, Rhizoma Atractylodis, Folium Perillae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae, Flos Lonicerae.
As preferred version wherein, described Chinese medicine formula comprises following mass fraction formula components:
Radix Polygalae 30 ~ 50 parts, Fructus Hippophae 40 ~ 60 parts, Cortex Magnoliae Officinalis 90 ~ 110 parts, Fructus Aurantii 80 ~ 100 parts, Rhizoma Atractylodis 50 ~ 70 parts, Folium Perillae 60 ~ 80 parts, Rhizoma Polygonati Odorati 100 ~ 120 parts, Radix Ophiopogonis 70 ~ 90 parts, Bulbus Lilii 60 ~ 80 parts, 100 ~ 120 parts, Folium Mori, Cortex Mori 90 ~ 110 parts, Radix Codonopsis 80 ~ 100 parts, 40 ~ 60 parts, Radix Glycyrrhizae, Flos Lonicerae 40 ~ 60 parts.
Further, in step one, carry out according to the following steps:
S1: Radix Polygalae, Fructus Hippophae, Cortex Magnoliae Officinalis, Fructus Aurantii are added the ethanol of 60%, carry out reflux 3 times, filter for subsequent use after backflow is merged;
S2: Rhizoma Atractylodis, Folium Perillae are collected distillate after adding water and distilling, distillate is filtered for subsequent use;
S3: by Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae, Flos Lonicerae eight taste medicine, decoct with water, obtains extracting solution, and carries out concentration to extracting solution, obtain concentrated solution;
S4: the backflow in the concentrated solution obtained in step S3 and step S1 is merged, carries out concentration further, obtain concentration liquid;
S5: the distillate obtained in the concentration liquid obtained in step S4 and step S2 is merged, obtains Chinese medicine extraction liquid.
Further, in step S3,
After by Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae seven taste Chinese medicine and water, routine 1:6 prepares feed liquid in mass ratio, first warm macerating 0.5 ~ 1 hour, heating makes feed liquid to boiling again, then little fire decocts 1 ~ 1.5 hour, then add Flos Lonicerae, continue decoction 0.5 ~ 1 hour, finally extract decoction liquor, with 120 order metre filter, obtain extracting solution;
Being got by extracting solution only, then add 4 times amount of water to clean medical material, carrying out secondary decoction: heating makes feed liquid to boiling, little fire decocts 1 ~ 1.5 hour, and extraction decoction liquor, with 120 order metre filter, obtains extracting solution;
Got by extracting solution only, then add 4 times amount of water to clean medical material, carry out three times and decoct: heating makes feed liquid to boiling, little fire decoction 1 ~ 1.5 hour, extracts decoction liquor, with 120 order metre filter, obtains extracting solution.
Further, in step S3:
Extracting solution is drawn into vacuum for-0.07MPa, temperature is in the environment of 70 DEG C, and being evaporated to relative density is 1.10-1.20, add the ethanol of 95%, make concentration of alcohol be down to 60%, stir 10 ~ 20 minutes, in cooling water environment, leave standstill 12 ~ 18 hours, obtain concentrated solution.
Further, in step S4:
Being merged by backflow in the supernatant of concentrated solution and step S1, is-0.075MPa in vacuum, and temperature is in the environment of 60 DEG C, and being evaporated to relative density is 1.10-1.20, obtains concentration liquid.
Further, in step 2:
Vitamin AD is added in Chinese medicine extraction liquid
3oil, containing 3-Hydroxyretinol 50 ~ 9,000,000 IU/1300-3300mg, vitamin D
385 ~ 2,400,000 IU/21-60mg, adjust PH to be 4.0-4.5 with hydrochloric acid, leave standstill 15 ~ 20 minutes, filter, filtrate by 0.45um filter, fill and get final product.
The invention provides a kind of using method of preventing and treating livestock and birds respiratory disease complexing agent, described complexing agent is used for laying hen and cultivates:
Laying hen has just gone out within shell 24 hours, and the 1000ML that added water by 0.2 ~ 0.4ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; After chickling in one week opens food, while feeding with chickling material, the 1000ML that added water by 0.3 ~ 0.5ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; While the chickling in 2-15 week is fed with large grain chickling material, the 1000ML that added water by 0.5 ~ 0.8ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; The chicken in 15-18 week, the 1000ML that added water by 0.8 ~ 1.2ML complexing agent dilutes, and ensures that 200 are freely drunk in chicken 2-3 hour complete, twice on the one; 19th week later one-tenth chicken, the 1000ML that added water by 1.5 ~ 2ML complexing agent dilutes, and ensureing 200, to become chickens freely to drink in 2-3 hour complete, twice on the one.
The invention provides the using method of another kind of control livestock and birds respiratory disease complexing agent, described complexing agent is used for broiler and cultivates:
Broiler has just gone out the 1000ML dilution that to be added water by 0.2 ~ 0.4ML complexing agent within shell 24 hours, ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; After the chickling of 1-10 age in days opens food, while feeding with chickling material, the 1000ML that added water by 0.3 ~ 0.5ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; The broiler of 20-30 age in days, the 1000ML that added water by 1 ~ 2ML complexing agent dilutes, and ensures that 200 are freely drunk in broiler 2-3 hour complete, twice on the one; Broiler after 30 ages in days, the 1000ML that added water by 2 ~ 3ML complexing agent dilutes, and ensures that 200 are freely drunk in broiler 2-3 hour complete, twice on the one.
In addition, the present invention also provides the using method of another kind of control livestock and birds respiratory disease complexing agent, and described complexing agent is used for boar and cultivates:
In the piglet stage, the 1000ML that added water by 25 ~ 35ML complexing agent dilutes, and guarantee piglet is freely drunk complete in 2-3 hour, twice on the one; Become the pig stage, the 1000ML that added water by 35 ~ 45ML complexing agent dilutes, ensure into freely drink in pig 2-3 hour complete, twice on the one; In the boar stage, the 1000ML that added water by 45 ~ 55ML complexing agent dilutes, and guarantee boar is freely drunk complete in 2-3 hour, twice on the one.
Beneficial effect of the present invention is as follows:
1, the raw materials used resources of Chinese medicinal herb of the present invention is extensive, cost is low;
2, high, the medicine noresidue of this complexing agent cure rate, to have no side effect, for control livestock and birds respiratory disease, there is significant effect;
3, scientific formulation of the present invention, the effect of there is cough-relieving, relieving asthma, eliminating the phlegm, preparation is liquid, easy to use;
4, the present invention adds vitamin AD
3oil composition, also has the effect promoting poultry bone growth, improves poultry added value.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment one:
Prevent and treat a preparation method for livestock and birds respiratory disease complexing agent, comprise the steps:
Get the raw materials ready by following Chinese medicine formula: Radix Polygalae 30g, Fructus Hippophae 40g, Cortex Magnoliae Officinalis 90g, Fructus Aurantii 80g, Rhizoma Atractylodis 50g, Folium Perillae 60g, Rhizoma Polygonati Odorati 100g, Radix Ophiopogonis 70g, Bulbus Lilii 60g, Folium Mori 100g, Cortex Mori 90g, Radix Codonopsis 80g, Radix Glycyrrhizae 40g, Flos Lonicerae 40g.
Vitamin AD used in the present embodiment
3oil, containing 3-Hydroxyretinol 500,000 IU/1300mg, vitamin D
3850000 IU/21mg.
Add 60% alcohol heating reflux 3 times with the Radix Polygalae 30g in above-mentioned Chinese medicine formula, Fructus Hippophae 40g, Cortex Magnoliae Officinalis 90g, Fructus Aurantii 80g, 2 hours first times, each 1 hour of third time of second time, filter liquor merges for subsequent use.
Rhizoma Atractylodis, Folium Perillae add water to distill and collect distillate, and distillate filters for subsequent use.
Remaining 8 taste medicines, except Flos Lonicerae, Rhizoma Polygonati Odorati 100g, Radix Ophiopogonis 70g, Bulbus Lilii 60g, Folium Mori 100g, Cortex Mori 90g, Radix Codonopsis 80g, Radix Glycyrrhizae 40g drop in extraction pot, adds water to the amount of clean medical material 6 times, warm macerating 1 hour, heating makes feed liquid to boiling, and little fire decocts 1.5 hours, adds Flos Lonicerae, continue decoction 0.5 hour, extract decoction liquor, by 120 order metre filter in fluid reservoir, obtain extracting solution;
Got by extracting solution only, then add 4 times amount of water to clean medical material, heating makes feed liquid to boiling, and the little fire decoction of second time 1 hour, extracts decoction liquor, by 120 order metre filter in fluid reservoir, obtain extracting solution; Third time decocts identical with second time.
Extracting solution is drawn into vacuum from fluid reservoir for-0.07MPa, temperature is concentrate in the concentrator of 70 DEG C, by outer circulation vacuum evaporator, carrying out being evaporated to relative density is 1.10-1.20 (surveying during 68-72 DEG C), concentrated solution is pumped into Alcohol-settling tank, adds the ethanol of 95%, make concentration of alcohol be down to 60%, stir 10 minutes, open cooling water and make it leave standstill 12 hours.
The supernatant of concentrated solution is evacuated in ethanol concentrator, merge with the backflow of four medicines such as Radix Polygalae, Cortex Magnoliae Officinalis, be-0.075MPa in vacuum, when temperature is 60 DEG C, by ethanol vacuum evaporator, being evaporated to relative density is 1.10-1.20 (surveying when 60 DEG C), obtain concentration liquid, valve-off, after concentration liquid is extracted into weighing area, merges with Rhizoma Atractylodis and Folium Perillae distillate.
Add vitamin AD
3oil, adjusts PH to be 4.0-4.5 with hydrochloric acid, leaves standstill 15 minutes, filters, filtrate by 0.45um accurate filter, fill and get final product.
Embodiment two:
Prevent and treat a preparation method for livestock and birds respiratory disease complexing agent, comprise the steps:
Get the raw materials ready by following Chinese medicine formula: Radix Polygalae 40g, Fructus Hippophae 50g, Cortex Magnoliae Officinalis 100g, Fructus Aurantii 90g, Rhizoma Atractylodis 60g, Folium Perillae 70, Rhizoma Polygonati Odorati 110g, Radix Ophiopogonis 80g, Bulbus Lilii 70g, Folium Mori 110g, Cortex Mori 100g, Radix Codonopsis 90g, Radix Glycyrrhizae 50g, Flos Lonicerae 50g.
Vitamin AD used in the present embodiment
3oil, containing vitamin A 6,250,000 IU/2300mg, vitamin D
31620000 IU/40mg.
The preparation of complexing agent is carried out by above-mentioned formula.
Embodiment three:
Prevent and treat a preparation method for livestock and birds respiratory disease complexing agent, comprise the steps:
Get the raw materials ready by following Chinese medicine formula: Radix Polygalae 50g, Fructus Hippophae 60g, Cortex Magnoliae Officinalis 110g, Fructus Aurantii 100g, Rhizoma Atractylodis 70g, Folium Perillae 80, Rhizoma Polygonati Odorati 120g, Radix Ophiopogonis 90g, Bulbus Lilii 80g, Folium Mori 120g, Cortex Mori 110g, Radix Codonopsis 100g, Radix Glycyrrhizae 600g, Flos Lonicerae 60g.
Vitamin AD used in the present embodiment
3oil, containing vitamin A 9,000,000 IU/3300mg, vitamin D
32400000 IU/60mg.
The preparation of complexing agent is carried out by above-mentioned formula.
Contrast experiment one:
Adopt the one control livestock and birds respiratory disease complexing agent of embodiments of the invention one to be used for laying hen to cultivate:
Chicken farm, Qingdao, winter, respiratory tract disease time occurred frequently.Choose 200 and just go out shell layer chicken, growing each stage takes in complexing agent of the present invention, and another 200 have just gone out shell layer chicken self-sow, do not taken in complexing agent of the present invention.The use procedure of complexing agent is as follows:
Laying hen has just gone out the 1000ML dilution that to be added water by 0.2ML complexing agent within shell 24 hours, ensures that 200 chickling are drunk in 3 hours complete, twice on the one; After laying chickling in one week opens food, while feeding with chickling material, the 1000ML that added water by 0.3ML complexing agent dilutes, and ensures that 200 chickling are freely drunk in 2.5 hours complete, twice on the one; While the chickling in 2-15 week is fed with large grain chickling material, the 1000ML that added water by 0.6ML complexing agent dilutes, and ensures that 200 chickling are freely drunk in 3 hours complete, twice on the one; The chicken in 15-18 week, the 1000ML that added water by 1.2ML complexing agent dilutes, and ensures that 200 chickens are freely drunk in 2 hours complete, twice on the one; 19th week later one-tenth chicken, the 1000ML that added water by 1.5ML complexing agent dilutes, and ensureing 200, to become chickens freely to drink in 3 hours complete, twice on the one.
Do not take in the chicken group of complexing agent of the present invention, within 14th, occur the sick chicken of cough, asthma, during 16 age in days, jumpbogroup appearance is coughed, sheds tears, is flowed the symptoms such as nose liquid, and has fragmentary death.Be respiratory tract disease through clinical diagnosis.
Take in the chicken group of complexing agent of the present invention, do not occur symptoms of respiratory disease.
To infect the chicken group isolation of respiratory tract disease, take in complexing agent of the present invention by its growth stage, after 1 day, the symptoms such as cough alleviate.After 3 days, situation takes a turn for the better, and a small amount of also have the respiratory symptom such as cough, stream nose liquid.After 7 days, chicken group each side recovering state is normal.
Do not take in the chicken group of complexing agent of the present invention after 19 weeks, average weight 1.3 kilograms, take in the chicken group of complexing agent of the present invention after 19 weeks, average weight 1.6 kilograms, physique is very large, and skeleton is healthy and strong.
Contrast experiment two:
Adopt the one control livestock and birds respiratory disease complexing agent of embodiments of the invention two to be used for laying hen to cultivate:
Chicken farm, Qingdao, winter, respiratory tract disease time occurred frequently.Choose 200 and just gone out shell broiler, growing each stage takes in complexing agent of the present invention, and another 200 have just gone out shell broiler self-sow, do not taken in complexing agent of the present invention.The use procedure of complexing agent is as follows:
Broiler has just gone out the 1000ML dilution that to be added water by 0.3ML complexing agent within shell 24 hours, ensures that 200 chickling are drunk in 3 hours complete, twice on the one; After the broiler chicks of 1-10 age in days opens food, while feeding with chickling material, the 1000ML that added water by 0.4ML complexing agent dilutes, and ensures that 200 chickling are freely drunk in 2.5 hours complete, twice on the one; The broiler of 20-30 age in days, the 1000ML that added water by 1.5ML complexing agent dilutes, and ensures that 200 broiler are freely drunk in 2 hours complete, twice on the one; Broiler after 30 ages in days, the 1000ML that added water by 3ML complexing agent dilutes, and ensures that 200 broiler are freely drunk in 3 hours complete, twice on the one.
Do not take in the chicken group of complexing agent of the present invention, within 15th, occur the sick chicken of cough, asthma, during 17 age in days, jumpbogroup appearance is coughed, sheds tears, is flowed the symptoms such as nose liquid.Be respiratory tract disease through clinical diagnosis.
Take in the chicken group of complexing agent of the present invention, do not occur symptoms of respiratory disease.
To infect the chicken group isolation of respiratory tract disease, take in complexing agent of the present invention by its growth stage, after 1 day, the symptoms such as cough alleviate.After 3 days, situation takes a turn for the better, and a small amount of also have the respiratory symptom such as cough, stream nose liquid.After 7 days, chicken group each side recovering state is normal.
Do not take in the chicken group of complexing agent of the present invention after 19 weeks, average weight 1.4 kilograms, take in the chicken group of complexing agent of the present invention after 19 weeks, average weight 1.6 kilograms, physique is very large, and skeleton is healthy and strong.
Contrast experiment three:
Adopt the one control livestock and birds respiratory disease complexing agent of embodiments of the invention three to be used for laying hen to cultivate:
Pingdu pig farm, winter, respiratory tract disease time occurred frequently.Choose 1 piglet that has just been born, growing each stage takes in complexing agent of the present invention, and another 1 just birth piglet self-sow, does not take in complexing agent of the present invention.The use procedure of complexing agent is as follows:
In the piglet stage, the 1000ML that added water by 30ML complexing agent dilutes, and ensures freely to drink in 2 hours complete, twice on the one; Become the pig stage, the 1000ML that added water by 40ML complexing agent dilutes, and ensures freely to drink in 2.5 hours complete, twice on the one; In the boar stage, the 1000ML that added water by 50ML complexing agent dilutes, and ensures freely to drink in 3 hours complete, twice on the one.
Do not take in the swinery of complexing agent of the present invention, within 20 days of the piglet stage, occur cough, asthma symptom, be mild respiratory disease through clinical diagnosis.
Taking in the piglet of complexing agent of the present invention, there is not symptoms of respiratory disease in generation phase.
To infect the piglet of respiratory tract disease, take in complexing agent of the present invention by its growth stage, after 3 days, situation takes a turn for the better, and the respiratory symptoms such as cough, stream nose liquid alleviate, and after 7 days, piglet each side recovering state is normal.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (10)
1. prevent and treat a preparation method for livestock and birds respiratory disease complexing agent, it is characterized in that: comprise the steps:
Step one: be that raw material carries out extraction process with Chinese medicine formula, obtain Chinese medicine extraction liquid;
Step 2: by vitamin AD
3oily and described Chinese medicine extraction liquid mixes, and carries out the preparation of complexing agent;
Described Chinese medicine formula comprises following composition: Radix Polygalae, Fructus Hippophae, Cortex Magnoliae Officinalis, Fructus Aurantii, Rhizoma Atractylodis, Folium Perillae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae, Flos Lonicerae.
2. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 1, is characterized in that: described Chinese medicine formula comprises following mass fraction formula components:
Radix Polygalae 30 ~ 50 parts, Fructus Hippophae 40 ~ 60 parts, Cortex Magnoliae Officinalis 90 ~ 110 parts, Fructus Aurantii 80 ~ 100 parts, Rhizoma Atractylodis 50 ~ 70 parts, Folium Perillae 60 ~ 80 parts, Rhizoma Polygonati Odorati 100 ~ 120 parts, Radix Ophiopogonis 70 ~ 90 parts, Bulbus Lilii 60 ~ 80 parts, 100 ~ 120 parts, Folium Mori, Cortex Mori 90 ~ 110 parts, Radix Codonopsis 80 ~ 100 parts, 40 ~ 60 parts, Radix Glycyrrhizae, Flos Lonicerae 40 ~ 60 parts.
3. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 2, is characterized in that: in step one, carries out according to the following steps:
S1: Radix Polygalae, Fructus Hippophae, Cortex Magnoliae Officinalis, Fructus Aurantii are added the ethanol of 60%, carry out reflux 3 times, filter for subsequent use after backflow is merged;
S2: Rhizoma Atractylodis, Folium Perillae are collected distillate after adding water and distilling, distillate is filtered for subsequent use;
S3: by Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae, Flos Lonicerae eight taste medicine, decoct with water, obtains extracting solution, and carries out concentration to extracting solution, obtain concentrated solution;
S4: the backflow in the concentrated solution obtained in step S3 and step S1 is merged, carries out concentration further, obtain concentration liquid;
S5: the distillate obtained in the concentration liquid obtained in step S4 and step S2 is merged, obtains Chinese medicine extraction liquid.
4. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 3, is characterized in that: in step S3,
After by Rhizoma Polygonati Odorati, Radix Ophiopogonis, Bulbus Lilii, Folium Mori, Cortex Mori, Radix Codonopsis, Radix Glycyrrhizae seven taste Chinese medicine and water, routine 1:6 prepares feed liquid in mass ratio, first warm macerating 0.5 ~ 1 hour, heating makes feed liquid to boiling again, then little fire decocts 1 ~ 1.5 hour, then add Flos Lonicerae, continue to decoct 0.5-1 hour, finally extract decoction liquor, with 120 order metre filter, obtain extracting solution;
Being got by extracting solution only, then add 4 times amount of water to clean medical material, carrying out secondary decoction: heating makes feed liquid to boiling, little fire decocts 1-1.5 hour, and extraction decoction liquor, with 120 order metre filter, obtains extracting solution;
Got by extracting solution only, then add 4 times amount of water to clean medical material, carry out three times and decoct: heating makes feed liquid to boiling, little fire decoction 1-1.5 hour, extracts decoction liquor, with 120 order metre filter, obtains extracting solution.
5. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 4, is characterized in that: in step S3:
Extracting solution is drawn into vacuum for-0.07MPa, temperature is in the environment of 70 DEG C, and being evaporated to relative density is 1.10-1.20, add the ethanol of 95%, make concentration of alcohol be down to 60%, stir 10 ~ 20 minutes, in cooling water environment, leave standstill 12 ~ 18 hours, obtain concentrated solution.
6. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 5, is characterized in that: in step S4:
Being merged by backflow in the supernatant of concentrated solution and step S1, is-0.075MPa in vacuum, and temperature is in the environment of 60 DEG C, and being evaporated to relative density is 1.10-1.20, obtains concentration liquid.
7. a kind of preparation method of preventing and treating livestock and birds respiratory disease complexing agent according to claim 6, is characterized in that: in step 2:
Vitamin AD is added in Chinese medicine extraction liquid
3oil mixing, adjusts PH to be 4.0-4.5 with hydrochloric acid, leaves standstill 15 ~ 20 minutes, filters, filtrate by 0.45um filter, fill and get final product.
8. a using method for the control livestock and birds respiratory disease complexing agent as described in claim 1-7 any one, is characterized in that: described complexing agent is used for laying hen and cultivates:
Laying hen has just gone out within shell 24 hours, and the 1000ML that added water by 0.2 ~ 0.4ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; After chickling in one week opens food, while feeding with chickling material, the 1000ML that added water by 0.3 ~ 0.5ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; While the chickling in 2-15 week is fed with large grain chickling material, the 1000ML that added water by 0.5 ~ 0.8ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; The chicken in 15-18 week, the 1000ML that added water by 0.8 ~ 1.2ML complexing agent dilutes, and ensures that 200 are freely drunk in chicken 2-3 hour complete, twice on the one; 19th week later one-tenth chicken, the 1000ML that added water by 1.5 ~ 2ML complexing agent dilutes, and ensureing 200, to become chickens freely to drink in 2-3 hour complete, twice on the one.
9. a using method for the control livestock and birds respiratory disease complexing agent as described in claim 1-7 any one, is characterized in that: described complexing agent is used for broiler and cultivates:
Broiler has just gone out the 1000ML dilution that to be added water by 0.2 ~ 0.4ML complexing agent within shell 24 hours, ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; After the chickling of 1-10 age in days opens food, while feeding with chickling material, the 1000ML that added water by 0.3 ~ 0.5ML complexing agent dilutes, and ensures that 200 are freely drunk in chickling 2-3 hour complete, twice on the one; The broiler of 20-30 age in days, the 1000ML that added water by 1 ~ 2ML complexing agent dilutes, and ensures that 200 are freely drunk in broiler 2-3 hour complete, twice on the one; Broiler after 30 ages in days, the 1000ML that added water by 2 ~ 3ML complexing agent dilutes, and ensures that 200 are freely drunk in broiler 2-3 hour complete, twice on the one.
10. a using method for the control livestock and birds respiratory disease complexing agent as described in claim 1-7 any one, is characterized in that: described complexing agent is used for boar and cultivates:
In the piglet stage, the 1000ML that added water by 25 ~ 35ML complexing agent dilutes, and guarantee piglet is freely drunk complete in 2-3 hour, twice on the one; Become the pig stage, the 1000ML that added water by 35 ~ 45ML complexing agent dilutes, ensure into freely drink in pig 2-3 hour complete, twice on the one; In the boar stage, the 1000ML that added water by 45 ~ 55ML complexing agent dilutes, and guarantee boar is freely drunk complete in 2-3 hour, twice on the one.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103120267A (en) * | 2013-02-28 | 2013-05-29 | 灵山县园丰牧业有限公司 | Feed for lingshan patridge chicken |
| CN103445029A (en) * | 2013-09-21 | 2013-12-18 | 广南(湛江)家丰饲料有限公司 | Pig feed additive capable of effectively preventing and treating respiratory diseases as well as improving immunity |
| CN104027442A (en) * | 2014-05-24 | 2014-09-10 | 潍坊市富言畜禽病诊疗中心 | Traditional Chinese medicine preparation adopted in green and residual medicine free broiler cultivation, preparation method thereof and method for cultivating broilers by using traditional Chinese medicine preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103120267A (en) * | 2013-02-28 | 2013-05-29 | 灵山县园丰牧业有限公司 | Feed for lingshan patridge chicken |
| CN103445029A (en) * | 2013-09-21 | 2013-12-18 | 广南(湛江)家丰饲料有限公司 | Pig feed additive capable of effectively preventing and treating respiratory diseases as well as improving immunity |
| CN104027442A (en) * | 2014-05-24 | 2014-09-10 | 潍坊市富言畜禽病诊疗中心 | Traditional Chinese medicine preparation adopted in green and residual medicine free broiler cultivation, preparation method thereof and method for cultivating broilers by using traditional Chinese medicine preparation |
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