CN105031670A - Gastrointestinal tract contrast agent - Google Patents
Gastrointestinal tract contrast agent Download PDFInfo
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- CN105031670A CN105031670A CN201510488459.5A CN201510488459A CN105031670A CN 105031670 A CN105031670 A CN 105031670A CN 201510488459 A CN201510488459 A CN 201510488459A CN 105031670 A CN105031670 A CN 105031670A
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a gastrointestinal tract contrast agent. The gastrointestinal tract contrast agent is prepared from the following ingredients in parts by weight: 50 to 70 parts of barium sulfate, 25 to 35 parts of traditional Chinese medicine extracts, 50 to 80 parts of honey and 300 to 500 parts of water, wherein the traditional Chinese medicine extracts are prepared from the following traditional Chinese medicine ingredients including 20 to 30 parts of atractylis ovata, 20 to 30 parts of grewia biloba, 20 to 30 parts of soybean black spermoderm, 10 to 15 parts of white flowers, 10 to 15 parts of tuber pinellia, 10 to 15 parts of red rice, 10 to 15 parts of pennisetum, 10 to 15 parts of artemisia stelleriana, 10 to 15 parts of incised spleenwort, 10 to 15 parts of fresh radix rehmanniae recens, 5 to 10 parts of rhizome and 5 to 10 parts of Chinese thorowax roots. The gastrointestinal tract contrast agent has the advantages that the too fast gastrointestinal peristalsis is inhibited; the assistance to the barium meal swallow is realized; the effects of nourish the gastrointestinal tract and inhibiting the gastrorrhagia are achieved.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, relate to a kind of gastrointestinal tract contrast medium, be specifically related to a kind of gastrointestinal tract contrast medium being applicable to the too fast patient of enterogastric peristalsis.
Background technology
Contrast agent is one of medicine the most often used in interventional radiology operation, is mainly used in the display of blood vessel, body cavity.Contrast agent can be divided into two large classes, high, the heavy high density contrast agent of atomic weight and the low-density contrast medium that atomic weight is low, proportion is little.Conventional high density contrast agent has barium sulfate and Operand.Wherein barium sulfate is generally used for gastrointestinal image inspection, and being added water by pure medical sulfuric acid barium dust is modulated into suspension.The concentration of barium sulfate represents with weight/volume (W/V) usually, and different with object according to the position checked, the concentration of barium sulfate used is also different.The multiplex barium meal of gastrointestinal imaging, i.e. digestive tract barium meal, refer to and use barium sulfate as contrast agent, show a kind of inspection method of digestive tract with or without pathological changes under roentgen radiation x.Different from clysis with barium, canel barium meal contrast examination takes in contrast agent by oral approach, can to whole digestive tract, and especially upper digestive tract carries out radioexmination more clearly.The gastrointestinal image being full of barium agent often covers small focus, therefore often existing highdensity barium agent in gastrointestinal tract is made by oral foaming agent, there is again low-density gas shadow, form gas barium contrast radiography, but when patient is generally reflected and gulped down barium, there will be the phenomenon being difficult to swallow and vomit.Need great quantity of water drinking after inspection or take cathartic, well discharging barium meal as early as possible, bring burden to the gastronintestinal system of patient's fragility, be unfavorable for later stage rehabilitation.
Barium meal, when specifically taking, often there will be the situation that barium meal one or two hour has just arrived ileocecus, and normal condition should at three to six hours, thus can not radiography smoothly.There is this situation normally because gastrointestinal peristalsis is too fast, accelerate barium meal displacement.Therefore, for this class patient in angiographic procedure can gastrointestinal peristalsis inhibition too fast, and can radiography smoothly, become problem demanding prompt solution.
Summary of the invention
The object of this invention is to provide a kind of gastrointestinal tract contrast medium, there is the advantage that gastrorrhagia was swallowed, and nourished gastrointestinal tract and suppressed to too fast, the auxiliary barium meal of gastrointestinal peristalsis inhibition.
The invention provides a kind of gastrointestinal tract contrast medium, formed by the preparation of raw material of following parts by weight: 50 ~ 70 parts, barium sulfate, Chinese medicine extract 25 ~ 35 parts, Mel 50 ~ 80 parts and 300 ~ 500 parts, water; Wherein Chinese medicine extract is formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Atractylodis Macrocephalae 20 ~ 30 parts, bilobed grewia 20 ~ 30 parts, Glycine max (L.) Merr. 20 ~ 30 parts, white residual flower 10 ~ 15 parts, the Rhizoma Pinelliae 10 ~ 15 parts, 10 ~ 15 parts, Monas cuspurpureus Went, Pennisetum centrasiaticum Tzvel 10 ~ 15 parts, Herba Artemisiae Sieversianae 10 ~ 15 parts, Herba Asplenii Incisi 10 ~ 15 parts, Radix Rehmanniae 10 ~ 15 parts, Rhizoma Cimicifugae 5 ~ 10 parts, Radix Bupleuri 5 ~ 10 parts.
More preferably formed by the preparation of raw material of following parts by weight: 60 parts, barium sulfate, Chinese medicine extract 30 parts, Mel 70 parts and 400 parts, water; Wherein Chinese medicine extract is formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Atractylodis Macrocephalae 25 parts, bilobed grewia 25 parts, Glycine max (L.) Merr. 25 parts, white residual flower 12 parts, the Rhizoma Pinelliae 12 parts, 12 parts, Monas cuspurpureus Went, Pennisetum centrasiaticum Tzvel 10 parts, Herba Artemisiae Sieversianae 10 parts, Herba Asplenii Incisi 10 parts, Radix Rehmanniae 10 parts, Rhizoma Cimicifugae 5 parts, Radix Bupleuri 5 parts.
Wherein, the preparation method of Chinese medicine extract takes raw material of Chinese medicine by above-mentioned parts by weight, adds water to submerge after mixing, decocts 30 ~ 50 minutes, and filter, filtrate spraying dry obtains Powder Extract.
The preparation method of gastrointestinal tract contrast medium of the present invention takes barium sulfate and Chinese medicine extract by above-mentioned parts by weight, and fully adding water with Mel mediation after mixing is suspension.
Pharmacology analysis:
Barium sulfate: white amorphous powder.Stable in properties, is insoluble in water, acid, alkali or organic solvent.Absorbable rod X-ray in gastrointestinal tract and make its effect of developing.
Mel: main trusted subordinate's pathogen, all infantile convulsion, settling five organs various symptoms and signs of deficiency, QI invigorating invigorating middle warmer, analgesic antidotal, and hundred medicines.Mainly play the effect of flavor adjustment and loosening bowel to relieve constipation in the present invention.
The Rhizoma Atractylodis Macrocephalae: there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, quench the thirst, antiabortive." adjustment gastrointestinal motility function: Rhizoma Atractylodis Macrocephalae decocting liquid is relevant with functional status residing for intestinal tube on the impact of rabbit motility of isolated ileocecal segment.Have excitation under normal circumstances, when intestinal tube is in excitatory state by acetylcholine effect, the Rhizoma Atractylodis Macrocephalae is inhibitory action; When intestinal tube is in inhibitory state by epinephrine effect, the Rhizoma Atractylodis Macrocephalae in excitation, all can make intestinal tube activity return to close to normal level again.
Bilobed grewia: acrid, sweet, warm.Invigorating the spleen and benefiting QI, treating spontaneous emission and leukorrhagia, expelling wind and removing dampness.For infantile malnutrition, insufficiency of the spleen chronic diarrhea, seminal emission, redly collapses, leucorrhea, uterine prolapse, proctoptosis, rheumatic arthritis.
Glycine max (L.) Merr.: sweet, warm.Return spleen, stomach warp.Expelling wind and removing dampness, invigorating the spleen and benefiting QI.Main arthralgia chiefly caused by damp pathogen, joint rash pain, vexed, the scrotum pruritus due to damp pathogen of insufficiency of the spleen lack of appetite, gastral cavilty harm.
White residual flower: bitter, puckery, cold.Clearing away summer-heat heat, removing dampness is turbid, pleasant stomach function regulating.Cure mainly summer-heat uncomfortable in chest, thirsty, vomiting, anorexia, aphtha erosion of the oral mucosa.
The Rhizoma Pinelliae: pungent, temperature.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Monas cuspurpureus Went: sweet, temperature.Help digestion stomach function regulating, promoting blood circulation and stopping pain, spleen invigorating, dry stomach.For retention of food and drink, chest and diaphragm is full vexed, dyspepsia.
Pennisetum centrasiaticum Tzvel: sweet, cold.Clearing away heat and promoting diuresis, cooling blood for hemostasis.Main pyretic stranguria, hematuria, cough due to lung-heat, epistaxis, gastric heat excessive thirst.
Herba Artemisiae Sieversianae: bitter in the mouth, micro-sweet, cool in nature.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis.Main swollen heat cough, laryngopharynx swelling and pain, jaundice due to damp-heat, hematodiarrhoea, gonorrhea, rheumatic arthralgia, haematemesis, spitting of blood, traumatic hemorrhage, scabies La malignant boil.
Herba Asplenii Incisi: bitter, micro-sweet, cool.Heat-clearing and toxic substances removing, cough-relieving sore-throat relieving, inducing diuresis and reducing edema, hemostasis and pain-relieving.For influenza, flu, cough, tonsillitis, parotitis, conjunctival congestion and swelling pain, enteritis, dysentery, agalactia; External is controlled skin ulcer and to be swollen furunculosis, and traumatic injury, eczema, burn and scald, knife injury is hemorrhage.
Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.Clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, spits blood, epistaxis, laryngopharynx swelling and pain.
Rhizoma Cimicifugae: pungent, micro-sweet, is slightly cold.Return lung, spleen, stomach, large intestine channel.Yang invigorating, delivers, rash, removing toxic substances.Control seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating; Sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, band, and uterus drops; Carbuncle sore tumefacting virus.
Radix Bupleuri: bitter, cool.Enter liver, gallbladder meridian.Separate the exterior and the interior, soothing the liver, yang invigorating.Control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.
Be directed to the too fast patient of enterogastric peristalsis, be mostly the disease of weakness of the spleen and stomach, and with incessant chronic diarrhea.In the present invention, the Rhizoma Atractylodis Macrocephalae, bilobed grewia, Glycine max (L.) Merr. are used for invigorating the spleen and benefiting QI, and gastrointestinal peristalsis inhibition is too fast; The pleasant stomach function regulating of white residual flower, the Rhizoma Pinelliae, Monas cuspurpureus Went, plays nourishing effect to stomach; Pennisetum centrasiaticum Tzvel, Herba Artemisiae Sieversianae, Herba Asplenii Incisi, Radix Rehmanniae have anastalsis, suppress barium meal to enter to take the gastrorrhagia problem occurred in process; Rhizoma Cimicifugae and Radix Bupleuri have the effect of antidiarrheal; Mel has the effect of flavor adjustment and lubrication intestinal.
Chinese medicine extract of the present invention sheerly Chinese medicine preparation, prove through years of researches and clinical practice: arranging in pairs or groups with barium sulfate, drug safety is reliable, medicine valency is cheap, carry taking convenience, avoid toxic and side effects and the anaphylaxis of chemicals, be applicable to the too fast patient of gastrointestinal peristalsis, and to stomach tool Yellow Gentian Extract, suppress the effect of gastrorrhagia and antidiarrheal, the micro-sweet problem improving barium meal and be difficult to swallow of taste.
Outcome measure:
Take effect: without senses of discomfort such as stomachache, vomitings, radiography is clear, start to discharge barium sulfate in 3 ~ 6 hours after checking.
Take a turn for the better: the senses of discomfort such as stomachache, vomiting alleviate, and radiography is clear, start to discharge barium sulfate in 2 ~ 3 hours after checking.
Invalid: all diseases are not improved, namely barium sulfate arrive ileocecus in 1 ~ 2 hour.
Take result: check patient 50 example, be the too fast patient of gastrointestinal peristalsis, the made gastrointestinal tract contrast medium of the present invention that swallows, if feel stimulating gastrointestinal road, have the gastric lavage immediately of allergic symptom emetic.After inspection, take effect 38 examples, accounts for 76%, and take a turn for the better 12 examples, accounts for 24%.
Attached several routine case is described further:
Case 1: Song, man, 44 years old, the regular pain of the intestines and stomach, did canel barium meal contrast examination at the beginning, and within 1 hour, barium meal arrives ileocecus, failed smooth radiography.Take contrast agent of the present invention to check, occur without stomachache, vomiting situation, radiography is clear, and stomach is fishhook-type, on an empty stomach without stomach pool stream; Antrum pleat irregular arrangement, increases thick.Gastric antrum community and stomach ditch plumpness, have no clear and definite ridge shadow and filling defect.Gastric antrum is little curved in dentation, and wriggle, contractile function is on the weak side; Without tenderness excitation.Check latter 4 hours namely to start to discharge barium sulfate.
Case 2: Lu, female, 32 years old, the few food of stomachache, do canel barium meal contrast examination at the beginning, within 2 hours, barium meal arrived ileocecus, and contrasting effects is undesirable.Take contrast agent of the present invention to check, stomachache symptom alleviates, and radiography is clear, cardia discovery without exception, stomach tension force is medium, in middle type, sees a small amount of retention liquid in gastral cavity, and gastric antrum portion mucosal pattern increases thick, coat of the stomach is still soft, and wriggle normal, pyloric cap form is normal.Check latter 3 hours namely to start to discharge barium sulfate.
Detailed description of the invention
Embodiment 1:
The present embodiment provides a kind of gastrointestinal tract contrast medium, is formed by the preparation of raw material of following parts by weight: 50 parts, barium sulfate, Chinese medicine extract 25 parts, Mel 50 parts and 300 parts, water; Wherein Chinese medicine extract is formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Atractylodis Macrocephalae 25 parts, bilobed grewia 25 parts, Glycine max (L.) Merr. 25 parts, white residual flower 12 parts, the Rhizoma Pinelliae 12 parts, 12 parts, Monas cuspurpureus Went, Pennisetum centrasiaticum Tzvel 10 parts, Herba Artemisiae Sieversianae 10 parts, Herba Asplenii Incisi 10 parts, Radix Rehmanniae 10 parts, Rhizoma Cimicifugae 5 parts, Radix Bupleuri 5 parts.
The preparation method of Chinese medicine extract takes raw material of Chinese medicine by above-mentioned parts by weight, adds water to submerge after mixing, decocts 35 minutes, and filter, filtrate spraying dry obtains Powder Extract.
The preparation method of gastrointestinal tract contrast medium takes barium sulfate and Chinese medicine extract by above-mentioned parts by weight, and fully adding water with Mel mediation after mixing is suspension.
Claims (3)
1. a gastrointestinal tract contrast medium, is characterized in that being formed by the preparation of raw material of following parts by weight: 50 ~ 70 parts, barium sulfate, Chinese medicine extract 25 ~ 35 parts, Mel 50 ~ 80 parts and 300 ~ 500 parts, water; Wherein Chinese medicine extract is formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Atractylodis Macrocephalae 20 ~ 30 parts, bilobed grewia 20 ~ 30 parts, Glycine max (L.) Merr. 20 ~ 30 parts, white residual flower 10 ~ 15 parts, the Rhizoma Pinelliae 10 ~ 15 parts, 10 ~ 15 parts, Monas cuspurpureus Went, Pennisetum centrasiaticum Tzvel 10 ~ 15 parts, Herba Artemisiae Sieversianae 10 ~ 15 parts, Herba Asplenii Incisi 10 ~ 15 parts, Radix Rehmanniae 10 ~ 15 parts, Rhizoma Cimicifugae 5 ~ 10 parts, Radix Bupleuri 5 ~ 10 parts.
2. a kind of gastrointestinal tract contrast medium as claimed in claim 1, is characterized in that being formed by the preparation of raw material of following parts by weight: 60 parts, barium sulfate, Chinese medicine extract 30 parts, Mel 70 parts and 400 parts, water; Wherein Chinese medicine extract is formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Atractylodis Macrocephalae 25 parts, bilobed grewia 25 parts, Glycine max (L.) Merr. 25 parts, white residual flower 12 parts, the Rhizoma Pinelliae 12 parts, 12 parts, Monas cuspurpureus Went, Pennisetum centrasiaticum Tzvel 10 parts, Herba Artemisiae Sieversianae 10 parts, Herba Asplenii Incisi 10 parts, Radix Rehmanniae 10 parts, Rhizoma Cimicifugae 5 parts, Radix Bupleuri 5 parts.
3. a kind of gastrointestinal tract contrast medium as claimed in claim 1 or 2, it is characterized in that: the preparation method of Chinese medicine extract is for take raw material of Chinese medicine by above-mentioned parts by weight, add water to submerge after mixing, decoct 30 ~ 50 minutes, filter, filtrate spraying dry obtains Powder Extract, is Chinese medicine extract.
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Cited By (9)
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| CN105435252A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to cold-heat complication type irritable bowel syndrome |
| CN105435251A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast media applicable to cold-heat complication type irritable bowel syndrome |
| CN105435250A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to liver depression and spleen vacuity type irritable bowel syndrome |
| CN105477649A (en) * | 2015-12-26 | 2016-04-13 | 江雨珊 | Contrast medium for cold-heat complication type irritable bowel syndrome |
| CN105536002A (en) * | 2015-12-26 | 2016-05-04 | 江雨珊 | Contrast agent suitable for liver-stagnation and spleen-deficiency type irritable bowel syndrome |
| CN105536001A (en) * | 2015-12-23 | 2016-05-04 | 江瑞平 | Contrast agent suitable for liver stagnation and spleen insufficiency type irritable bowel syndrome |
| CN105617409A (en) * | 2015-12-26 | 2016-06-01 | 江雨珊 | Contrast agent suitable for cold-heat complication type irritable bowel syndrome |
| CN105641718A (en) * | 2015-12-26 | 2016-06-08 | 江雨珊 | Contrast medium suitable for liver depression and spleen deficiency type irritable bowel syndrome |
| CN108553652A (en) * | 2018-05-31 | 2018-09-21 | 郝润松 | A kind of x-ray barium enema examination enteron aisle contrast medium and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105435252A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to cold-heat complication type irritable bowel syndrome |
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| CN105435250A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to liver depression and spleen vacuity type irritable bowel syndrome |
| CN105536001A (en) * | 2015-12-23 | 2016-05-04 | 江瑞平 | Contrast agent suitable for liver stagnation and spleen insufficiency type irritable bowel syndrome |
| CN105477649A (en) * | 2015-12-26 | 2016-04-13 | 江雨珊 | Contrast medium for cold-heat complication type irritable bowel syndrome |
| CN105536002A (en) * | 2015-12-26 | 2016-05-04 | 江雨珊 | Contrast agent suitable for liver-stagnation and spleen-deficiency type irritable bowel syndrome |
| CN105617409A (en) * | 2015-12-26 | 2016-06-01 | 江雨珊 | Contrast agent suitable for cold-heat complication type irritable bowel syndrome |
| CN105641718A (en) * | 2015-12-26 | 2016-06-08 | 江雨珊 | Contrast medium suitable for liver depression and spleen deficiency type irritable bowel syndrome |
| CN108553652A (en) * | 2018-05-31 | 2018-09-21 | 郝润松 | A kind of x-ray barium enema examination enteron aisle contrast medium and preparation method thereof |
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Address after: Qingdao City, Shandong province 266042 four Road No. 127 Applicant after: Zhongxin Hospital, Qingdao Address before: Yantai City, Shandong province 266000 four Road No. 127 Applicant before: Zhongxin Hospital, Qingdao |
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Application publication date: 20151111 |