CN103690901A - Traditional Chinese medicine for treating cholelithiasis and preparation method thereof - Google Patents

Traditional Chinese medicine for treating cholelithiasis and preparation method thereof Download PDF

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Publication number
CN103690901A
CN103690901A CN201310738403.1A CN201310738403A CN103690901A CN 103690901 A CN103690901 A CN 103690901A CN 201310738403 A CN201310738403 A CN 201310738403A CN 103690901 A CN103690901 A CN 103690901A
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chinese medicine
cholelithiasis
treatment
medicine
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杜乐栋
于群
刘杰
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杜乐栋
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Abstract

The invention discloses a traditional Chinese medicine for treating cholelithiasis. The traditional Chinese medicine for comprises the following medicinal raw materials by weight: 60g corn stigma, 30g oriental wormwood, 30g longhairy antenoron herb, 15g lygodium japonicum, 15g gardenia jasminoides, 30g lalang grass rhizome, 10g egg shell, 10g chingma abutilon seed, 10g bupleurum, 15g turmeric, 10g trogopterus dung, 5g gecko, 10g crinis carbonisatus, 10g endothelium corneum gigeriae galli, 60g Chinese yam and 10g roasted liquorice. The traditional Chinese medicine is taken along with warm water after half an hour after meals in the morning and in the evening; 15 days is a course of treatment, and usually, the cholelithiasis can be cured after 1-2 courses of treatment; wine, seafood and the like are forbidden in the process of taking the traditional Chinese medicine; and through combination of Chinese herbs, compared with the prior art, the traditional Chinese medicine has the advantages of small usage amount, quick effect, small side effects, and capability of achieving an aim of treating symptoms and root causes from both inside and outside, capability of inhibiting the development of a disease and relieving clinical symptoms, and good therapeutic effect.

Description

A kind of Chinese medicine for the treatment of cholelithiasis and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine for the treatment of cholelithiasis and preparation method thereof.
Background technology
Cholelithiasis refers to the caused disease of the calculus occurring in gallbladder, is a kind of commonly encountered diseases.With age growth, sickness rate also raises gradually, and women is obviously more than male.
As lithogenous universal law, they have the separating out of bile component, precipitation, nucleation and gather the basic processes such as growth.Its pathogeny comprises several key elements, first, and the necessary supersaturation of the cholesterol in bile or calcium; Secondly, solute must be from solution nucleation be solid crystal shape and precipitate; The 3rd, crystalline solid must assemble and merge to form calculus, and crystal is being dispersed throughout the mucus of gallbladder wall, increases and assemble in gel, and the undermined cholelithiasis that is conducive to of gall bladder emptying forms.
Along with growth in the living standard, the change of dietary habit, the improvement of sanitary condition, the cholelithiasis of China be take gallbladder cholesterol calculus as main by take the bile pigment calculus of bile duct as main changing into gradually.The method of traditional treatment cholelithiasis is to carry out with operation method, and large to human injury, wound area is large, and adopts Western medicine to treat, and side effect is large, serious to human body infringement.
Summary of the invention
The object of the invention is for the deficiencies in the prior art, provide little to patient's side effect, a kind of Chinese medicine for the treatment of cholelithiasis that therapeutic effect is good.
For addressing the above problem, the present invention by the following technical solutions:
A Chinese medicine for the treatment of cholelithiasis, is characterized in that: the crude drug by following weight forms: 60 grams of Stigma Maydis, 30 grams of Herba Artemisiae Scopariaes, 30 grams of Herba Lysimachiaes, 15 grams of Spora Lygodii, 15 grams of SHANZHIZI, 30 grams of Rhizoma Imperataes, 10 grams of Ovum crusta Gallus domesticuss, 10 grams of Semen Abutilis, 10 grams of Radix Bupleuri, 15 grams of RADIX CURCUMAEs, 10 grams of Oletum Trogopteroris, 5 grams of Gekko Swinhonis, 10 grams of Crinis Carbonisatus, 10 grams of Endothelium Corneum Gigeriae Galli, 60 grams of Rhizoma Dioscoreaes, 10 grams of Radix Glycyrrhizae Preparatas.
Below the further improvement to technique scheme:
A preparation method for the treatment of the Chinese medicine of cholelithiasis, comprises the following steps:
1), the Herba Artemisiae Scopariae of above-mentioned weight, Herba Lysimachiae, Spora Lygodii, SHANZHIZI, Rhizoma Imperatae, Semen Abutili, Radix Bupleuri, RADIX CURCUMAE, Oletum Trogopterori, Crinis Carbonisatus, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae, Radix Glycyrrhizae Preparata are added the water of 10 times of total raw material medicine weight decoct, after boiling, slow fire boiling 20 minutes again, leaches medicinal liquid A;
2), the Gekko Swinhonis of above-mentioned weight (processing dry) is ground to form to fine powder B;
3), by the Ovum crusta Gallus domesticus calcination of above-mentioned weight to carbon shape, then wear into fine powder C;
4), rice vinegar that the Stigma Maydis of above-mentioned weight is added to 10 times of Stigma Maydis weight decocts 10-15 minute, obtains medicinal liquid D;
5), medicine juice A and medicinal liquid D are merged, merging to such an extent that add powder B, powder C in medicinal liquid, decoct 10-15 minute, obtain medicine.
Rice vinegar in described step 4) is 8 degree rice vinegars.
The temperature that described step 4) decocts is at 60-70 degree.
The temperature decocting in described step 5) is at 60-70 degree.
Instructions of taking: above-mentioned herb liquid is divided into two parts, in early, after supper half an hour decoction being taken warmly, within 15 days, be 1 course for the treatment of, can cure general 1~2 course for the treatment of, notes taking the food such as the interim taboo drinks of Chinese medicine of the present invention and seafood.
Stigma Maydis: nature and flavor with return through: property flatly, sweet in the mouth, returns bladder, liver, gallbladder meridian.Function cures mainly: inducing diuresis to remove edema, dampness removing jaundice eliminating.For edema, jaundice.
Herba Artemisiae Scopariae: nature and flavor with return through: cold nature, bitter in the mouth, pungent, returns spleen, stomach, liver, gallbladder meridian.Function cures mainly: eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice.For jaundice oliguria, hygropyrexia heat-damp in summer, eczema pruritus.
Herba Lysimachiae: nature and flavor with return through: cold nature, sweet in the mouth, salty, returns liver, gallbladder, kidney, urinary bladder channel.Function cures mainly: dampness removing jaundice eliminating, inducing diuresis for treating stranguria syndrome, removing toxic substances and promoting subsidence of swelling.For jaundice due to damp-heat, gallbladder-distention hypochondriac pain, stranguria caused by urinary stone, pyretic stranguria, difficulty and pain in micturition, carbuncle furuncle, snake bite and insect sting.
Spora Lygodii: nature and flavor with return through: cold in nature, sweet in the mouth, salty, returns bladder, small intestine meridian.Function cures mainly: eliminating damp-heat, treating stranguria pain relieving.For pyretic stranguria, stranguria caused by urinary stone, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain.
SHANZHIZI: nature and flavor with return through: cold in nature, bitter in the mouth, GUIXIN, lung, tri-jiao channel.Function cures mainly: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Externally used detumescence pain relieving.Vexed for calentura, jaundice due to damp-heat, the puckery pain of stranguria, heat in blood is told nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Rhizoma Imperatae: nature and flavor with return through: cold in nature, sweet in the mouth, returns lung, stomach, urinary bladder channel.Function cures mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.For heat in blood, spit blood, epistaxis, hematuria, calentura excessive thirst, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.
Ovum crusta Gallus domesticus: nature and flavor with return through: property flat, lightly seasoned.Function cures mainly: convergence antacid, replenish the calcium.For chronic gastritis, gastric and duodenal ulcers, rickets.
Semen Abutili: nature and flavor with return through: cool in nature, sweet in the mouth, puckery, returns large intestine, small intestinal, urinary bladder channel.Function cures mainly: inducing diuresis for treating stranguria syndrome, stimulating milk secretion, intestine moistening.For stranguria, galactostasis, distending pain of the breast, constipation.
Radix Bupleuri: nature and flavor with return through: cold nature, acrid in the mouth, hardship, return liver, gallbladder, lung meridian.Function cures mainly: induce sweat and bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
RADIX CURCUMAE: nature and flavor with return through: cold in nature, acrid in the mouth, hardship, return liver, the heart, lung meridian.Function cures mainly: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.For the twinge of the breast side of body, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, distending pain of the breast, calentura coma, epilepsy is gone mad, and heat in blood is told nosebleed, jaundice dark coloured urine.
Oletum Trogopterori: nature and flavor with return through: warm in nature, bitter in the mouth, salty, sweet, returns Liver Channel.Function cures mainly: promoting blood circulation and stopping pain, removing stasis to stop bleeding.For stagnation of blood stasis, bitterly demonstrate,prove, stagnation of blood stasis goes out blood disorder.
Gekko Swinhonis: nature and flavor with return through: cold in nature, slightly poisonous, salty in the mouth.Function cures mainly: dispels the wind, and arresting convulsion, eliminating stagnation, removing toxic substances.Control paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil.
Crinis Carbonisatus: nature and flavor with return through: property flatly, bitter in the mouth, returns liver, stomach warp.Function cures mainly: astringing to arrest bleeding, blood stasis dispelling, diuresis.For spitting blood, spitting of blood, epistaxis, stranguria with blood, hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, dysuria.
Endothelium Corneum Gigeriae Galli: nature and flavor with return through: property flatly, sweet in the mouth, returns spleen, stomach, small intestinal, urinary bladder channel.Function cures mainly: invigorating the stomach and promoting digestion, arresting seminal emission, treating stranguria fossil.For food stagnation, do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of stranguria caused by urinary stone, gallbladder-distention hypochondriac pain.
Rhizoma Dioscoreae: nature and flavor with return through: property flatly, sweet in the mouth, returns spleen, lung, kidney channel.Function cures mainly: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
Radix Glycyrrhizae Preparata: nature and flavor with return through: property flat, sweet in the mouth, GUIXIN, lung, spleen, stomach warp.Function cures mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, tired weak, severe palpitation, irregularly intermittent and regularly intermittent pulse.
In this prescription, Stigma Maydis, Herba Artemisiae Scopariae clearing gallbladder dampness removing calculus are monarch drug, Herba Lysimachiae, Spora Lygodii, SHANZHIZI, Rhizoma Imperatae, Ovum crusta Gallus domesticus, the molten gallbladder calculus of Semen Abutili heat clearing away are ministerial drug, Radix Bupleuri, Radix Curcumae, Oletum Trogopterori, Gekko Swinhonis depressed liver-energy dispersing and function of gallbladder promoting are invigorated blood circulation as adjuvant drug, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae air making-up and spleen enlivening are also adjuvant drug, and Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription is for making medicine.
The present invention combines by said medicine, compared with prior art, has the following advantages: have medication few, instant effect, side effect is little, can reach inside and outside and execute, the object of giving consideration to both the incidental and fundamental, can suppress the development of the state of an illness, alleviates clinical symptoms, therapeutic effect is good, by the present invention's 200 examples, wherein effective 180 examples, significant 170 examples of effect, without 20 examples of therapeutic effect, therapeutic effect is obvious, use the present invention to treat, there is no untoward reaction.
The specific embodiment
Embodiment, treat a Chinese medicine for cholelithiasis, by the crude drug of following weight, formed: 60 grams of Stigma Maydis, 30 grams of Herba Artemisiae Scopariaes, 30 grams of Herba Lysimachiaes, 15 grams of Spora Lygodii, 15 grams of SHANZHIZI, 30 grams of Rhizoma Imperataes, 10 grams of Ovum crusta Gallus domesticuss, 10 grams of Semen Abutilis, 10 grams of Radix Bupleuri, 15 grams of RADIX CURCUMAEs, 10 grams of Oletum Trogopteroris, 5 grams of Gekko Swinhonis, 10 grams of Crinis Carbonisatus, 10 grams of Endothelium Corneum Gigeriae Galli, 60 grams of Rhizoma Dioscoreaes, 10 grams of Radix Glycyrrhizae Preparatas.
The preparation method of above-mentioned Chinese medicine, comprises the following steps:
1), the Herba Artemisiae Scopariae of above-mentioned weight, Herba Lysimachiae, Spora Lygodii, SHANZHIZI, Rhizoma Imperatae, Semen Abutili, Radix Bupleuri, RADIX CURCUMAE, Oletum Trogopterori, Crinis Carbonisatus, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae, Radix Glycyrrhizae Preparata are added the water of 10 times of total raw material medicine weight decoct, after boiling, slow fire boiling 20 minutes again, leaches medicinal liquid A;
2), the Gekko Swinhonis of above-mentioned weight (processing dry) is ground to form to fine powder B;
3), by the Ovum crusta Gallus domesticus calcination of above-mentioned weight to carbon shape, then wear into fine powder C;
4), rice vinegar that the Stigma Maydis of above-mentioned weight is added to 10 times of Stigma Maydis weight decocts 10-15 minute, obtains medicinal liquid D;
5), medicine juice A and medicinal liquid D are merged, merging to such an extent that add powder B, powder C in medicinal liquid, decoct 10-15 minute, obtain medicine.
In this prescription, Stigma Maydis, Herba Artemisiae Scopariae clearing gallbladder dampness removing calculus are monarch drug, Herba Lysimachiae, Spora Lygodii, SHANZHIZI, Rhizoma Imperatae, Ovum crusta Gallus domesticus, the molten gallbladder calculus of Semen Abutili heat clearing away are ministerial drug, Radix Bupleuri, Radix Curcumae, Oletum Trogopterori, Gekko Swinhonis depressed liver-energy dispersing and function of gallbladder promoting are invigorated blood circulation as adjuvant drug, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae air making-up and spleen enlivening are also adjuvant drug, and Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription is for making medicine.
The present invention combines by said medicine, compared with prior art, has the following advantages: there is medication few, and instant effect, side effect is little, can reach inside and outside and execute, and the object of giving consideration to both the incidental and fundamental, can suppress the development of the state of an illness, alleviates clinical symptoms, and therapeutic effect is good.
Through great many of experiments, applicant finds to adopt said medicine combination and weight compatibility, and its therapeutic effect of the Chinese medicine making is compared with other weight compatibilities, evident in efficacy, is better than other weight compatibility far away.
Through experiment, in the situation that other conditions are constant, Gekko Swinhonis (processing dry) grinds to form fine powder, and the curative effect that makes medicine is not better than processs dry curative effect of medication Gekko Swinhonis.
Through experiment, in the situation that other conditions are constant, Ovum crusta Gallus domesticus calcination, to carbon shape, is then worn into fine powder, in the medicine of rear interpolation, than only adding Ovum crusta Gallus domesticus, compares, and its drug effect has great improvement, can have larger lifting to drug effect.
Experimental result is in Table 1
Table 1
Through experiment, in the situation that other conditions are constant, the rice vinegar that Stigma Maydis is added to 10 times of Stigma Maydis weight decocts 10-15 minute; The curative effect of the medicine of gained increases significantly with the drug effect only Stigma Maydis water being decocted, and experimental result is in Table 2.
Table 2
Through experiment, when rice vinegar is 8 degree rice vinegar, the lifting of its drug effect is the most remarkable.
The decoction temperature experiment of Stigma Maydis and rice vinegar the results are shown in Table 3.
Table 3
As shown in table 3, the temperature that described step 4) decocts is when 60-70 spends, and the drug effect of Stigma Maydis can be given full play to, and when temperature is when spending lower than 60 degree with higher than 70, the drug effect that makes medicine is poor.
For further investigating clinical efficacy and the safety of the present embodiment medicine, we have selected the case of 400 routine measles to carry out clinical trial to the treatment curative effect of medicine of the present invention.
The patient of 400 routine cholelithiasis is divided into two groups at random, every group of 200 examples.In matched group, male's 120 examples, women's 80 examples; Following 20 examples of 30 years old age, 30-40 year above 60 examples, 40 years old 120 above example; In treatment group, male's 125 examples, women's 75 examples; Following 25 examples of 30 years old age, 30-40 year above 65 examples, 40 years old 110 above example.
Two groups of cases are Epidemiological Analysis by statistics at aspects such as sex, age, the courses of disease, has comparability.
Matched group adopts appropriate exercise, and rational diet, adopts traditional Western medicine to treat; The oral medicine of the present invention for the treatment of group.
Criterion of therapeutical effect: cure: clinical symptoms, sign disappear, and transference cure, has no adverse reaction.Effective: clinical symptoms, sign obviously alleviate, and symptom obviously alleviates.Effective: clinical symptoms, sign alleviate, and symptom alleviates.Invalid: clinical symptoms, sign are not improved.
Curative effect comparision result after two groups of case treatments is as table 4.
Table 4
Group Number of cases Cure n(%) Effective n(%) Effective n(%) Invalid n(%)
Treatment group 200 120(60) 170(85) 180(90) 20(10)
Matched group 200 110(55) 130(65) 140(70) 60(30)
By above-mentioned contrast, can find out and use treatment by Chinese herbs cholelithiasis of the present invention, therapeutic effect is remarkable, compares with application Western medicine, is better than Western medicine, and cure rate is high, and medical expense is low, and few to the injury of health.
The present invention has no side effect, and does not develop immunity to drugs, and be 3 days each course for the treatment of, can cure after taking 2 to 3 courses for the treatment of, and cure rate reaches more than 92%, and effective percentage reaches 98%.
The present invention combines by said medicine, compared with prior art, has the following advantages: have medication few, instant effect, side effect is little, can reach inside and outside and execute, the object of giving consideration to both the incidental and fundamental, can suppress the development of the state of an illness, alleviates clinical symptoms, therapeutic effect is good, by the present invention's 200 examples, wherein effective 180 examples, significant 170 examples of effect, without 20 examples of therapeutic effect, therapeutic effect is obvious, use the present invention to treat, there is no untoward reaction.
Case 1, patient Lee, female, 45 years old, suffer from gallbladder muddy stone, take this Chinese medicine after one course for the treatment of, through color ultrasound examination, cholelithiasis granule obviously reduces, and after two courses for the treatment of, calculus granule disappears.
Case 2, patient Lee so-and-so, man, 55 years old, suffer from choledocholithiasis, fear operation, take this Chinese medicine after two courses for the treatment of, through color ultrasound examination, choledocholithiasis volume obviously reduces, after four courses for the treatment of, calculus disappears.

Claims (5)

1. a Chinese medicine for the treatment of cholelithiasis, is characterized in that: the crude drug by following weight portion forms: 60 grams of Stigma Maydis, 30 grams of Herba Artemisiae Scopariaes, 30 grams of Herba Lysimachiaes, 15 grams of Spora Lygodii, 15 grams of SHANZHIZI, 30 grams of Rhizoma Imperataes, 10 grams of Ovum crusta Gallus domesticuss, 10 grams of Semen Abutilis, 10 grams of Radix Bupleuri, 15 grams of RADIX CURCUMAEs, 10 grams of Oletum Trogopteroris, 5 grams of Gekko Swinhonis, 10 grams of Crinis Carbonisatus, 10 grams of Endothelium Corneum Gigeriae Galli, 60 grams of Rhizoma Dioscoreaes, 10 grams of Radix Glycyrrhizae Preparatas.
2. a kind of preparation method for the treatment of the Chinese medicine of cholelithiasis as claimed in claim 1, comprises the following steps:
1), the Herba Artemisiae Scopariae of above-mentioned weight, Herba Lysimachiae, Spora Lygodii, SHANZHIZI, Rhizoma Imperatae, Semen Abutili, Radix Bupleuri, RADIX CURCUMAE, Oletum Trogopterori, Crinis Carbonisatus, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae, Radix Glycyrrhizae Preparata are added the water of 10 times of total raw material medicine weight decoct, after boiling, slow fire boiling 20 minutes again, leaches medicinal liquid A;
2), the Gekko Swinhonis of above-mentioned weight (processing dry) is ground to form to fine powder B;
3), by the Ovum crusta Gallus domesticus calcination of above-mentioned weight to carbon shape, then wear into fine powder C;
4), rice vinegar that the Stigma Maydis of above-mentioned weight is added to 10 times of Stigma Maydis weight decocts 10-15 minute, obtains medicinal liquid D;
5), medicine juice A and medicinal liquid D are merged, merging to such an extent that add powder B, powder C in medicinal liquid, decoct 10-15 minute, obtain medicine.
3. a kind of preparation method for the treatment of the Chinese medicine of cholelithiasis as claimed in claim 2, is characterized in that: the rice vinegar in described step 4) is 8 degree rice vinegars.
4. a kind of preparation method for the treatment of the Chinese medicine of cholelithiasis as claimed in claim 2 or claim 3, is characterized in that: the temperature that described step 4) decocts is at 60-70 degree.
5. a kind of preparation method for the treatment of the Chinese medicine of cholelithiasis as claimed in claim 2, is characterized in that: the temperature decocting in described step 5) is at 60-70 degree.
CN201310738403.1A 2013-12-30 2013-12-30 Traditional Chinese medicine for treating cholelithiasis and preparation method thereof Pending CN103690901A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375856A (en) * 2017-09-18 2017-11-24 河南千方药业有限公司 A kind of cholagogic fossil tea and preparation method thereof

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101112589A (en) * 2007-07-30 2008-01-30 牛昱翔 Liver-boosting calculus-discharging Chinese traditional medicine

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Publication number Priority date Publication date Assignee Title
CN101112589A (en) * 2007-07-30 2008-01-30 牛昱翔 Liver-boosting calculus-discharging Chinese traditional medicine

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Title
檀桥: "三金排石汤治疗胆结石症102 例临床观察", 《中医药学报》 *

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375856A (en) * 2017-09-18 2017-11-24 河南千方药业有限公司 A kind of cholagogic fossil tea and preparation method thereof

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