CN105031425A - Traditional Chinese medicine composition for treating acnes - Google Patents
Traditional Chinese medicine composition for treating acnes Download PDFInfo
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- CN105031425A CN105031425A CN201510222158.8A CN201510222158A CN105031425A CN 105031425 A CN105031425 A CN 105031425A CN 201510222158 A CN201510222158 A CN 201510222158A CN 105031425 A CN105031425 A CN 105031425A
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Abstract
The invention provides a traditional Chinese medicine composition for treating acnes. In the technical scheme, the traditional Chinese medicine composition includes following active components which are prepared from the following raw material medicines through extraction, by weight: 20 parts of picris divaricata, 10 parts of floscopa scandens, 15 parts of fructus forsythiae, 10 parts of mulberry leaves, 3 parts of platycodon grandiflorum, 15 parts of oldenlandia diffusa, 10 parts of cortex lycii radicis, 10 parts of cortex moutan, 10 parts of lithospermum, 3 parts of herba schizonepetae, 6 parts of cassia twigs, 15 parts of cortex dictamni, 15 parts of smilax glabra, 6 parts of mint and 6 parts of radix glycyrrhizae. The traditional Chinese medicine composition is processed to form a tincture through corresponding methods. The traditional Chinese medicine composition has the effect of treating acnes.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition of Acne treatment and method for making and application.
Background technology
Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, and clinical manifestation is to be apt to occur in the pleomorphism skin lesion such as acne, pimple, pustule, tuberosity of face for feature.The factors such as the generation of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.Existing market is badly in need of a kind of medicine for external use of Acne treatment.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation of Acne treatment.
Another object of the present invention is the Chinese medicine preparation preparation method and application providing a kind of Acne treatment.
Technical scheme: the object of the invention is by following scheme realize:
A Chinese medicine composition for Acne treatment, the active component contained by it is extracted by following raw materials in part by weight medicine proportioning and is prepared from: Picris divaricata 20 parts, poly-flowers and plants 10 parts, Fructus Forsythiae 15 parts, 10 parts, Folium Mori, Radix Platycodonis 3 parts, Herba Hedyotidis Diffusae 15 parts, Cortex Lycii 10 parts, Cortex Moutan 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Herba Schizonepetae 3 parts, Ramulus Cinnamomi 6 parts, Cortex Dictamni 15 parts, Rhizoma Smilacis Glabrae 15 parts, Herba Menthae 6 parts, 6 parts, Radix Glycyrrhizae.
The Chinese medicine composition of above-mentioned Acne treatment, described crude drug adds substrate and makes tincture after extracting.
The Chinese medicine composition of above-mentioned Acne treatment, described substrate is 75% ethanol 50-70 part.
The method of the Chinese medicine composition of above-mentioned Acne treatment, preparation process is: get above-mentioned medical material and merge, pulverize, make solvent soaking, get supernatant, be prepared into tincture, fill after 5-20 hour with 75% ethanol.
The preparation method of the Chinese medicine composition of above-mentioned Acne treatment, makes solvent soaking 10 hours with 75% ethanol in step.
The Chinese medicine composition of above-mentioned Acne treatment is preparing the application in Retinoids, Retin-A, Renova, Accutane.
Picris divaricata is Compositae sonchus plant Herba Sonchi Oleracei SonchusoleraceusL., with all herbal medicine.The four seasons can adopt, using fresh herb or dry.Heat-clearing and toxic substances removing, cooling blood for hemostasis.For enteritis, dysentery, acute icteric infectious hepatitis, appendicitis, mastitis, stomatitis, pharyngitis, tonsillitis, spits blood, epistaxis, and spitting of blood, has blood in stool, metrorrhagia; Carbuncle pyogenic infections from tumour or sore is controlled in external, otitis media.
Poly-flowers and plants, Latin is called FloscopascandensLour., for Commelianaceae plant gathers the herb of flowers and plants.Produce south China, Zhejiang, Jiangxi, Fujian, Taiwan, Hunan, Yunnan, Sichuan, Tibet, Tropical Asian, the torrid zone, Oceania.Herb: heat-clearing and toxic substances removing, inducing diuresis to remove edema, antiinflammatory, invigorates blood circulation.For furuncle toxic swelling, lymphadenectasis, edema, acute nephritis, internal injury, conjunctival congestion and swelling pain.The present invention is with all herbal medicine.All the other are pharmacopeia kind.
Found by clinical and experimental study, Chinese medicine composition of the present invention has good Acne treatment effect.Therefore, present invention also offers the purposes of aforementioned pharmaceutical compositions, namely the Chinese medicine composition of above-mentioned Acne treatment is preparing the application in Retinoids, Retin-A, Renova, Accutane.
Beneficial effect:
From theory of Chinese medical science, in we, heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, anti-bacterial, anti-itching, be used for the treatment of acne.Formulation is reasonable, and compatibility is rigorous.The present invention consists of Chinese crude drug, has no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, in conjunction with detailed description of the invention, the present invention is further described as follows:
Embodiment 1: get Picris divaricata 20g, poly-flowers and plants 10g, Fructus Forsythiae 15g, Folium Mori 10g, Radix Platycodonis 3g, Herba Hedyotidis Diffusae 15g, Cortex Lycii 10g, Cortex Moutan 10g, Radix Arnebiae (Radix Lithospermi) 10g, Herba Schizonepetae 3g, Ramulus Cinnamomi 6g, Cortex Dictamni 15g, Rhizoma Smilacis Glabrae 15g, Herba Menthae 6g, the merging of Radix Glycyrrhizae 6g medical material, pulverize, solvent soaking is made with 75% ethanol 60 parts, supernatant is got, fill after 10 hours.
2, clinical observation and model case:
Physical data: all 15 ~ 35 years old case ages, 214 years old mean age, the course of disease 6 months-3 years, average course of disease 2.1 years.Totally 80 examples, adopt random number method, patient are divided into two groups at random, treatment group 40 example: wherein man 15 example, female 25 example, by acne classification level Four improvement staging, and point I level acne 22 example, II level acne 18 example; Matched group 40 example: wherein man 22 example, female 18 example, I level acne 16 example, II level acne 24 example.Through statistical analysis, above two groups of cases are in sex, age, the state of an illness, and no significant difference (P > 0.05), has comparability.
Diagnostic criteria: (1) diagnosis is with reference to " clinical dermatology ", " People's Republic of China's traditional Chinese medicine industry standard-TCM Dermatology disease Standardization of diagnosis and curative effect ": have typical clinical symptoms and sign, skin lesion is mainly being dispersed in property blackhead, inflamed papules, pustule, tuberosity, the cyst of involving facial area, is diagnosed as acne person.(2) exclusion standard: 1. with infectious disease person, as: hepatitis, syphilis, acquired immune deficiency syndrome (AIDS) etc.; 2. can not chronotherapeutic person on demand; 3. the person that accepts other treatment in therapeutic process.
Therapeutic Method: treatment group uses traditional Chinese medicinal lotion of the present invention, washout potion every day, three times on the one; Matched group only gives the external of clindamycin and metronidazole liniment, every day 2 times.Two groups of homogeneous Zhou Weiyi courses for the treatment of.
Criterion of therapeutical effect: formulate " Chinese medicine (new drug) guideline of clinical investigations " with reference to Ministry of Health of the People's Republic of China: recovery from illness: facial acne erythra all disappears, and occurs, only stay pigmentation without new breakout; Effective: acne deflorescence more than 70%, inflammation obviously alleviates, and occurs without new erythra; Effective: acne erythra obviously disappears 20%-70%, there is a small amount of new erythra to occur; Invalid: acne erythra obviously disappears 20%, or still have new erythra to occur.
Therapeutic outcome: add up curative effect after treating two courses for the treatment of, treatment group 40 example, 17 examples of wherein fully recovering, effective 14 examples, effective 5 examples, invalid 5 examples, total effective rate arrives 87.5%; Matched group 40 example, 3 examples of wherein fully recovering, effective 8 examples, effective 6 examples, invalid 23 examples, effective percentage reaches 42.5%.Two groups of cure rates, total effective rate has significant difference (P < 0.05).
Claims (5)
1. the Chinese medicine composition of an Acne treatment, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine proportioning and is prepared from: Picris divaricata 20 parts, poly-flowers and plants 10 parts, Fructus Forsythiae 15 parts, 10 parts, Folium Mori, Radix Platycodonis 3 parts, Herba Hedyotidis Diffusae 15 parts, Cortex Lycii 10 parts, Cortex Moutan 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Herba Schizonepetae 3 parts, Ramulus Cinnamomi 6 parts, Cortex Dictamni 15 parts, Rhizoma Smilacis Glabrae 15 parts, Herba Menthae 6 parts, 6 parts, Radix Glycyrrhizae.
2. the Chinese medicine composition of Acne treatment as claimed in claim 1, is characterized in that, described crude drug makes tincture through soaking with substrate, and described substrate is 75% ethanol 50-70 part.
3. the Chinese medicine composition of Acne treatment as claimed in claim 1, is characterized in that, preparation method comprises the steps: that getting above-mentioned medical material merges, and pulverizes, makes solvent soaking, get supernatant, be prepared into tincture, fill after 5-20 hour with 75% ethanol.
4. the Chinese medicine composition of Acne treatment according to claim 3, is characterized in that making solvent soaking 10 hours with 75% ethanol in preparation method step.
5. the application of the Chinese medicine composition of Acne treatment in Retinoids, Retin-A, Renova, Accutane as claimed in claim 1.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003026585A (en) * | 2001-07-10 | 2003-01-29 | Maruzen Pharmaceut Co Ltd | Lipase inhibitor |
CN1618454A (en) * | 2004-07-14 | 2005-05-25 | 江西神飞九保健品有限公司 | Medicinal composition for treating acne and beauty-care, and its prepn. method |
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2015
- 2015-05-05 CN CN201510222158.8A patent/CN105031425A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003026585A (en) * | 2001-07-10 | 2003-01-29 | Maruzen Pharmaceut Co Ltd | Lipase inhibitor |
CN1618454A (en) * | 2004-07-14 | 2005-05-25 | 江西神飞九保健品有限公司 | Medicinal composition for treating acne and beauty-care, and its prepn. method |
Non-Patent Citations (3)
Title |
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易尚文: "桑菊饮加减治疗寻常痤疮临床观察", 《中国中西医结合皮肤性病学杂志》 * |
赵进: "中药内服外用治疗痤疮38例", 《中国现代药物应用》 * |
鲁兆麟等: "《中医各家学说》", 31 July 2005, 中国协和医科大学出版社 * |
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Application publication date: 20151111 |