CN103948878B - A kind of Chinese medicine composition for the treatment of osteopathia - Google Patents
A kind of Chinese medicine composition for the treatment of osteopathia Download PDFInfo
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- CN103948878B CN103948878B CN201410214861.XA CN201410214861A CN103948878B CN 103948878 B CN103948878 B CN 103948878B CN 201410214861 A CN201410214861 A CN 201410214861A CN 103948878 B CN103948878 B CN 103948878B
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Abstract
The present invention relates to a kind of Chinese medicine composition for the treatment of osteopathia, it is made up of Chinese crude drugs such as Rhizoma Atractylodis, Massa Medicata Fermentata, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Gentianae, Radix Clematidis, Ramulus Cinnamomi.The Traditional Chinese medicine composition formula for the treatment of osteopathia of the present invention is reasonable, has benefiting QI and nourishing blood, invigorating the kidney and strengthening the bones, blood circulation promoting and blood stasis dispelling, the effect of relaxing muscles and tendons and activating QI and blood in the collateral, all effective to the various orthopaedic disease for the treatment of.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of Chinese medicine composition for the treatment of osteopathia.
Background technology
Knee joint osseous arthritis mainly refers to due to knee cartilage degeneration, hyperosteogeny, the chronic joint disease of the one caused therefrom, it is the diseases of middle-and old-aged person that extensive degenerative change occurs a kind of osteoarthrosis structure common and multiple clinically, its main clinical manifestation is arthralgia, swelling, limitation of activity etc., with work, larger impact is caused to the orthobiosis of patient, seriously constrains the raising of patients ' life quality.If treatment not in time, then can cause it that disabled probability occurs constantly increases, and even injures the life security of patient.Therefore, clinician should give patient and diagnose accurately, and carries out symptomatic treatment to patient, effectively to improve the state of an illness of patient, and promotes the raising of patients ' life quality, ensures normally to walk.
Current treatment knee joint osseous arthritis is main mainly with oral formulations such as tablet, capsule, powder and decoctions, but because oral formulations easily causes gastrointestinal side effect, and osteopathia mostly is wound, oral formulations cannot directly apply to trauma site, and therefore its curative effect is not often fine.
Summary of the invention
The object of the invention is the defect in order to overcome prior art oral formulations and a kind of Chinese medicine composition for the treatment of osteopathia is provided.
In order to realize object of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of osteopathia, it is characterized in that, it is made up of Chinese crude drug.
Preferably, described Chinese crude drug comprises the material of following weight proportioning: Rhizoma Atractylodis 8-12 part, Massa Medicata Fermentata 6-10 part, Rhizoma Et Radix Notopterygii 5-15 part, Rhizoma Chuanxiong 8-15 part, Radix Angelicae Dahuricae 10-20 part, Radix Gentianae 5-10 part, Radix Clematidis 8-13 part, Ramulus Cinnamomi 4-8 part, Semen Persicae 8-12 part, Radix Stephaniae Tetrandrae 3-8 part, Flos Carthami 8-12 part, Fructus Chaenomelis 15-20 part, Herba Siegesbeckiae 10-20 part, Radix Achyranthis Bidentatae 5-15 part, Radix Angelicae Pubescentis 8-16 part, Herba Agrimoniae 15-25 part, Radix Salviae Miltiorrhizae 15-22 part, Radix Angelicae Sinensis 10-20 part, Lepidinm meyenii Walp 8-12 part, Radix Glycyrrhizae Preparata 4-8 part, Rhizoma Gastrodiae 8-12 part, Cortex Eucommiae 8-15 part, Rhizoma Curcumae Longae 3-7 part, Semen Coicis 8-12 part, Medulla Tetrapanacis 1-5 part, Cordyceps 1-5 part and Squama Manis 1-10 part.
Preferably, described Chinese crude drug comprises the material of following weight proportioning: Rhizoma Atractylodis 10 parts, Massa Medicata Fermentata 8 parts, Rhizoma Et Radix Notopterygii 10 parts, Rhizoma Chuanxiong 10 parts, the Radix Angelicae Dahuricae 15 parts, Radix Gentianae 8 parts, Radix Clematidis 10 parts, Ramulus Cinnamomi 5 parts, 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 5 parts, 10 parts, Flos Carthami, Fructus Chaenomelis 15 Fen, Herba Siegesbeckiae 15 parts, Radix Achyranthis Bidentatae 10 parts, Radix Angelicae Pubescentis 10 parts, Herba Agrimoniae 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Angelicae Sinensis 15 parts, Lepidinm meyenii Walp 10 parts, Radix Glycyrrhizae Preparata 5 parts, 10 parts, Rhizoma Gastrodiae, the Cortex Eucommiae 10 parts, 5 parts, Rhizoma Curcumae Longae, Semen Coicis 10 parts, Medulla Tetrapanacis 2 parts, Cordyceps 2 parts and Squama Manis 5 parts.
More preferably, described Chinese crude drug also comprises the material of following weight proportioning: Hirudo 10 parts, Ligustrum groffiae Merr. 12 parts, Galla Chinensis 5 parts, Fructus Mume 8 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 20 parts, the Fructus Kochiae 10 parts, Herba Otteliae Alismoidis 15 parts, Cortex Acanthopancis 10 parts, Radix Puerariae 12 parts, Herba Urariae Lagopodioidis 10 parts, Rhizoma Coptidis 8 parts, Herba Moslae Soochowensis 10 parts, Radix Sanguisorbae 6 parts, Cortex Phellodendri 7 parts and Flos Lonicerae 8 parts.
Preferably, described Chinese medicine composition can be ointment.
In the present invention:
Massa Medicata Fermentata be the medicines such as Herba polygoni hydropiperis, Herba Artemisiae Annuae, Semen Armeniacae Amarum add flour or wheat bran mixed after, through the herbal leaven of fermentation, such as can purchased from Sichuan Fu Zheng Pharmaceutical Co., Ltd, details can see State Food and Drug Administration website.
Lepidinm meyenii Walp (Maca), have another name called Peruvianginseng, mack, maca-maca, maino, ayakchichira, ayakwillku etc., originate in the mountain area, Andean, South America of height above sea level 3500 ~ 4500 meters, mainly being distributed in now the Puno ecotope in the middle part of Peru and Peru the southeastern city of Puno, is Cruciferae (Cruciferae) Lepidium (Lepidium) plant.
Herba Urariae Lagopodioidis is the herb of leguminous plant leopard cat tail grass (Urarialagopodioides (L.) Desv. [HedysarumlagopodioidesL.]).
The Traditional Chinese medicine composition formula for the treatment of osteopathia of the present invention is reasonable, has benefiting QI and nourishing blood, invigorating the kidney and strengthening the bones, blood circulation promoting and blood stasis dispelling, the effect of relaxing muscles and tendons and activating QI and blood in the collateral, all effective to the various orthopaedic disease for the treatment of.
Detailed description of the invention
Embodiment 1: the preparation of ointment
Take Rhizoma Atractylodis 10 grams, Massa Medicata Fermentata 8 grams, Rhizoma Et Radix Notopterygii 10 grams, Rhizoma Chuanxiong 10 grams, the Radix Angelicae Dahuricae 15 grams, Radix Gentianae 8 grams, Radix Clematidis 10 grams, Ramulus Cinnamomi 5 grams, 10 grams, Semen Persicae, Radix Stephaniae Tetrandrae 5 grams, 10 grams, Flos Carthami, Fructus Chaenomelis 15 grams, Herba Siegesbeckiae 15 grams, Radix Achyranthis Bidentatae 10 grams, Radix Angelicae Pubescentis 10 grams, Herba Agrimoniae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Radix Angelicae Sinensis 15 grams, Lepidinm meyenii Walp 10 grams, Radix Glycyrrhizae Preparata 5 grams, 10 grams, Rhizoma Gastrodiae, the Cortex Eucommiae 10 grams, 5 grams, Rhizoma Curcumae Longae, Semen Coicis 10 grams, Medulla Tetrapanacis 2 grams, Cordyceps 2 grams and Squama Manis 5 grams, pulverize, cross 80 mesh sieves, add 120 grams of lanolines, stir, then be dispensed in 20 flexible pipes, obtain.
Embodiment 2: the preparation of ointment
Take Rhizoma Atractylodis 10 grams, Massa Medicata Fermentata 8 grams, Rhizoma Et Radix Notopterygii 10 grams, Rhizoma Chuanxiong 10 grams, the Radix Angelicae Dahuricae 15 grams, Radix Gentianae 8 grams, Radix Clematidis 10 grams, Ramulus Cinnamomi 5 grams, 10 grams, Semen Persicae, Radix Stephaniae Tetrandrae 5 grams, 10 grams, Flos Carthami, Fructus Chaenomelis 15 grams, Herba Siegesbeckiae 15 grams, Radix Achyranthis Bidentatae 10 grams, Radix Angelicae Pubescentis 10 grams, Herba Agrimoniae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Radix Angelicae Sinensis 15 grams, Lepidinm meyenii Walp 10 grams, Radix Glycyrrhizae Preparata 5 grams, 10 grams, Rhizoma Gastrodiae, the Cortex Eucommiae 10 grams, 5 grams, Rhizoma Curcumae Longae, Semen Coicis 10 grams, Medulla Tetrapanacis 2 grams, Cordyceps 2 grams, Squama Manis 5 grams, Hirudo 10 grams, Ligustrum groffiae Merr. 12 grams, Galla Chinensis 5 grams, Fructus Mume 8 grams, Philippine Paphiopedilum (Concolor Paphiopedilum) 20 grams, the Fructus Kochiae 10 grams, Herba Otteliae Alismoidis 15 grams, Cortex Acanthopancis 10 grams, Radix Puerariae 12 grams, Herba Urariae Lagopodioidis 10 grams, Rhizoma Coptidis 8 grams, Herba Moslae Soochowensis 10 grams, Radix Sanguisorbae 6 grams, Cortex Phellodendri 7 grams and Flos Lonicerae 8 grams, pulverize, cross 80 mesh sieves, add 120 grams of lanolines, stir, then be dispensed in 20 flexible pipes, obtain.
Experimental example
Select 78 routine knee of patients with osteoarthritis, all patients all meet the diagnostic criteria (Chen Jupeng of knee joint osteoarthritis in " new Chinese medicine guideline of clinical investigations ", Wang Peimin, Ma Yong. Xu Jianan teaches combination of inner and outside diagnosis and treatment knee joint osteoarthritis experience [M]. Nanjing University of Traditional Chinese Medicine's journal, 2011,27 (6); 1002-1005.).Wherein, man 40 example, the age 52-76 year between, the mean age is 61.3 years old, female 38 example, the age 53-78 year between, the mean age is 63.1 years old.78 routine patients are divided into 2 groups, observation group 39 example, the ointment of preparation in embodiment 2 is adopted to treat, matched group 39 example, the ointment of preparation in embodiment 1 is adopted to treat, 2 groups of physical data are through statistical procedures, and there was no significant difference (P > 0.05), has comparability.
Observation group is when treating, and every day 2 times, treat for sore place uniform application 1 pipe ointment 7 days is 1 course for the treatment of at every turn.Painful area skin has redness, festers, pimple person's forbidding.
Matched group is when treating, and every day 2 times, treat for sore place uniform application 1 pipe ointment 7 days is 1 course for the treatment of at every turn.Painful area skin has redness, festers, pimple person's forbidding.
Criterion of therapeutical effect
With reference to the efficacy assessment standard (Chen Jupeng in " new Chinese medicine guideline of clinical investigations ", Wang Peimin, Ma Yong. Xu Jianan teaches combination of inner and outside diagnosis and treatment knee joint osteoarthritis experience [M]. Nanjing University of Traditional Chinese Medicine's journal, 2011,27 (6); 1002-1005.).Cure: clinical symptoms and sign disappear, pain, swelling are alleviated, and can carry out free activity, not affect its normal live and work, and quality of life improves; Effective: clinical symptoms and sign have and disappear largely, and pain, swelling are obviously alleviated, and can carry out free activity, and have slight impact to its normal live and work, quality of life is greatly increased; Take a turn for the better: clinical symptoms and sign disappear to some extent, and pain, swelling are alleviated to some extent, and free activity is subject to certain restriction, have impact to a certain degree to its normal live and work, quality of life increases; Invalid: clinical symptoms and sign do not disappear, have larger restriction to its free activity, and the state of an illness presents the trend constantly increased the weight of, with work, serious impact is created to the orthobiosis of patient, constrains the raising of patients ' life quality.
Therapeutic outcome
Statistical analysis adopts SPSS13.0 statistics software to carry out t inspection to this paper obtained experimental data.Experimental result sees the following form.
Compare with matched group, * P < 0.05.
Claims (2)
1. treat the Chinese medicine composition of osteopathia for one kind, it is characterized in that, it is made up of following Chinese medicine, described Chinese crude drug is the material of following weight proportioning: Rhizoma Atractylodis 10 parts, Massa Medicata Fermentata 8 parts, Rhizoma Et Radix Notopterygii 10 parts, Rhizoma Chuanxiong 10 parts, the Radix Angelicae Dahuricae 15 parts, Radix Gentianae 8 parts, Radix Clematidis 10 parts, Ramulus Cinnamomi 5 parts, 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 5 parts, 10 parts, Flos Carthami, Fructus Chaenomelis 15 parts, Herba Siegesbeckiae 15 parts, Radix Achyranthis Bidentatae 10 parts, Radix Angelicae Pubescentis 10 parts, Herba Agrimoniae 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Angelicae Sinensis 15 parts, Lepidinm meyenii Walp 10 parts, Radix Glycyrrhizae Preparata 5 parts, 10 parts, Rhizoma Gastrodiae, the Cortex Eucommiae 10 parts, 5 parts, Rhizoma Curcumae Longae, Semen Coicis 10 parts, Medulla Tetrapanacis 2 parts, Cordyceps 2 parts, Squama Manis 5 parts, Hirudo 10 parts, Ligustrum groffiae Merr. 12 parts, Galla Chinensis 5 parts, Fructus Mume 8 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 20 parts, the Fructus Kochiae 10 parts, Herba Otteliae Alismoidis 15 parts, Cortex Acanthopancis 10 parts, Radix Puerariae 12 parts, Herba Urariae Lagopodioidis 10 parts, Rhizoma Coptidis 8 parts, Herba Moslae Soochowensis 10 parts, Radix Sanguisorbae 6 parts, Cortex Phellodendri 7 parts and Flos Lonicerae 8 parts.
2. the Chinese medicine composition for the treatment of osteopathia according to claim 1, is characterized in that, described Chinese medicine composition is ointment.
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| CN104127824B (en) * | 2014-08-07 | 2017-02-15 | 山东中医药大学 | Traditional Chinese medicine composition for external cold compress for relieving swelling and pain and application thereof |
| CN106214795A (en) * | 2016-08-29 | 2016-12-14 | 李朝伟 | A kind of compositions treating osteopathia and preparation method thereof |
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| CN102579743B (en) * | 2012-03-30 | 2014-04-23 | 丁义 | Externally applied ointment mainly for treating bone fracture and degenerative osteopathy and preparation method thereof |
| CN103041077A (en) * | 2013-01-15 | 2013-04-17 | 长治市郊区黄碾镇中心卫生院 | Drug for treating rheumatoid arthritis |
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