CN102813811B - External paste used for promoting postoperation wound healing of caesarean delivery - Google Patents

External paste used for promoting postoperation wound healing of caesarean delivery Download PDF

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CN102813811B
CN102813811B CN 201210336090 CN201210336090A CN102813811B CN 102813811 B CN102813811 B CN 102813811B CN 201210336090 CN201210336090 CN 201210336090 CN 201210336090 A CN201210336090 A CN 201210336090A CN 102813811 B CN102813811 B CN 102813811B
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radix
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wound healing
external paste
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CN102813811A (en
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冯晓华
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Abstract

The invention discloses an external paste used for promoting postoperation wound healing of caesarean delivery, belonging to the technical field of Chinese medicine composition. The external paste is compounded from Chinese angelica, prepared rhizome rehmannia, codonopsis pilosula, radix ophiopogonis, dipsacus root, Chinese herbaceous peony, peach kernel, safflower, motherwort and liquorice, and the medicines are compounded to realize synergistic effect of the medicines, thus postoperation wound healing of the caesarean delivery can be effectively promoted. The external paste disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, fighting bacteria and diminishing inflammation, drawing out the pus and detoxifying, promoting tissue regeneration and enhancing immunity of the organism, has the advantages of short treatment course, obvious curative effect and no toxic or side effect, and effective rate of the external paste in one treatment course is 95% and the effective rate of the external paste in two treatment courses is 99% according to observation and statistics of fifty eight clinical patients.

Description

A kind of externally used paste that promotes wound healing behind the cesarean section
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of externally used paste that promotes wound healing behind the cesarean section.
Background technology
Have a delicate constitution because of its patient behind the cesarean section, the otch obstinate is common symptom, at present medical circle mainly is to be main Therapeutic Method by bactericidal antiphlogistic, antibiotics and the sulfa drugs of adopting more, this Therapeutic Method only is fit to the treatment of first phase, to the second stage of incision in treatment weak effect, and very serious to the damage of skin, be not suitable for using, also there are some to adopt application compress now, as rubber plaster etc., but they often do not have the function of antiinflammatory, and relatively poor with the antiphlogistic antibacterial adaptability of Western medicine, cause surface healing inner still in the phenomenon of inflammation easily, cause patient's otch obstinate, bad during fashion.
Summary of the invention
The present invention is directed to above existing issue and propose a kind of externally used paste that can promote wound healing behind the cesarean section, this externally used paste has the effect of blood circulation promoting and blood stasis dispelling, anti-inflammation, enhancing human body immunity power.
The present invention selects Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Codonopsis, Radix Ophiopogonis, Radix Dipsaci, Radix Paeoniae, Semen Persicae, Flos Carthami, Herba Leonuri, Radix Glycyrrhizae to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively promote the healing of otch behind the cesarean section.
Wherein: Radix Angelicae Sinensis: be Umbelliferae PlantRadix Angelicae Sinensis [2]The drying of Angelica sinensis (Oliv.) Diels RootNature and flavor are sweet, hot, temperature.Return liver, the heart, spleen channel.Has the effect of regulating body's immunity, anti-inflammation, enriching blood and invigorating blood circulation.
Radix Rehmanniae Preparata: for ScrophulariaceaePlant Radix Rehmanniae(formal name used at school: tuber Rehmannia glutinosa).Nature and flavor are sweet, tepor.Return liver, kidney channel.Effect with nourishing YIN and supplementing blood, vital essence replenishing and marrow benifiting.The Radix Rehmanniae Preparata alcohol extract is given mouse gavaging, and the macrophage function that suppressed by carrageenin is had significant protective effect; Antagonist forms cell inhibitory action.The traditional Chinese medical science is thought cloudy blood homology, nourishes blood, YIN nourishing should carry out synchronously, and Radix Angelicae Sinensis and Radix Rehmanniae Preparata collocation have two big benefits, the one, reach the purpose of yin nourishing by enriching blood, and YIN nourishing is again one of effective ways of enriching blood.The 2nd, Radix Angelicae Sinensis itself has extraordinary blood circulation-promoting functions, tonify without causing stagnation, Radix Rehmanniae Preparata and Radix Angelicae SinensisBe combined in one with outclassing prescription usefulness.
Radix Codonopsis: be campanulaceae PlantRadix Codonopsis, plain flower Radix Codonopsis, radix codonpsis tangshen, pipe flower Radix Codonopsis, The globe daisy Radix Codonopsis, the gray wool Radix Codonopsis root.Property is put down, sweet in the mouth, little acid.Return spleen, Lung meridianHave invigorating the spleen and replenishing QI, Spleen invigoratingThe effect of lung benefiting. Radix Codonopsis extractCan strengthen mouse peritoneal MacrophageEngulf chicken ErythrocyteAbility, can promote lymphocytic conversion, strengthen AntibodyCelliferous function improves antibody titer.
Radix Ophiopogonis: be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (T.f) Ker-Gawl..Sweet, the little hardship of nature and flavor is slightly cold.GUIXIN, lung, stomach warp.Has the effect that nourishing blood to promote the production of body fluid, lung moistening clear away heart-fire.
Radix Dipsaci: be Dipsacaceae plant Radix Dipsaci Dipsacus asperoidesC. the dry root of Y. Cheng et T .M. Ai..Bitter in the mouth; Hot; Slightly warm in nature.Return liver; Kidney channel.Have effects such as invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating.Carbuncle and ulcer there is the effect of evacuation of pus, hemostasis, analgesia, promotion tissue regeneration.
The Radix Paeoniae Alba: be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).The nature and flavor picric acid, cold.Go into liver, spleen channel.Have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the effect of antiperspirant.White peony root's total glycoside has antiinflammatory and function dependency ground immunoregulation effect to adjuvant arthritis rats; Radix Paeoniae Alba extract can significantly suppress the impatient property of rat Ovum Gallus domesticus album inflammation Edema, granuloma induced by implantation of cotton pellets is also had the effect that suppresses its hypertrophy.White peony root's total glycoside has regulating action to phagocytosis of macrophages; White peony root's total glycoside produces interleukin-1 to lipopolysaccharide-induced rat abdominal cavity macrophage and has the effect that low concentration promotes and high concentration suppresses, because interleukin-1 all plays an important role in the formation of immunomodulating and chronic inflammation disease.
Semen Persicae: for RosaceaeThe dry mature seed of plant peach Prunus persica (L.) Batsch or mountain peach Prunus davidiana (Carr.) Franch..Nature and flavor hardship, sweet, flat.GUIXIN, liver, Large intestine channelEffect with blood circulation promoting and blood stasis dispelling.Semen Persicae has the inflammation of promotion Absorption, to the inflammation initial stage, stronger exudation effect is arranged.
Flos Carthami: for ChrysanthemumThe tubular corolla of the plant Flos Carthami Carthamus tinctorius L. of section.Warm in nature, acrid in the mouth.Has promoting blood circulation to restore menstrual flow, the effect of the silt pain relieving of loosing.The Flos Carthami polysaccharide can promote to drench cell transformation, increases the cell number that splenocyte forms the sheep red blood cell plaque, and the immunosuppressive action of antagonism meticortelone etc. show that it is a kind of new, worth further immunomodulator of research.Carthamus yellow has and suppresses the rabbit platelet aggregation effect that ADP induces very significantly, and the platelet that ADP has assembled is also had very significantly depolymerisation.
Herba Leonuri: be the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..Feeble QI, mildly bitter flavor.Go into the heart, liver, Urinary bladder channelEffect with blood circulation promoting and blood stasis dispelling, experiment in vitro proves, intact animal's platelet aggregation effect that Herba Leonuri and extract thereof have antagonism ADP to induce. experiment also proves that Herba Leonuri can significantly reduce total number of blood platelet and the interior platelet of alveolar wall blood capillary and the aggregation thereof in the peripheral circulation in the body.Herba Leonuri has remarkable dissolution to rabbit pulmonary circulation red thrombus, and in addition, Herba Leonuri also has the effects such as cellular immunization of enhancing body.Herba Leonuri infusion (1:4) to being permitted skin pathogenicity funguses such as blue achorion, ulotrichy microspore's tinea bacterium, epidermophyton rubrum, star-shaped nocardia, all has inhibitory action in various degree in vitro.
Radix Glycyrrhizae: be dicotyledon Pulse familyThe Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensisFisch., Glycyrrhiza inflata Bat. G. inflataBat., or Glycyrrhiza glabra L. G. glabraL. root reaches RhizomeProperty is put down, and sweet in the mouth is returned 12 warps.Has heat-clearing and toxic substances removing, the effect of coordinating the actions of various ingredients in a prescription.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: 20-30 parts of Radix Angelicae Sinensis, 10-15 parts of Radix Rehmanniae Preparata, 10-20 parts of Radix Codonopsis, 10-15 parts of Radix Ophiopogonis, 10-15 parts of Radix Dipsacis, 10-15 parts of the Radix Paeoniae Albas, 10-15 parts in Semen Persicae, 10-15 parts on Flos Carthami, 25-40 parts of Herba Leonuris, 1-5 parts in Radix Glycyrrhizae.
Wherein be preferably: 24 parts of Radix Angelicae Sinensis, 12 parts of Radix Rehmanniae Preparata, 15 parts of Radix Codonopsis, 12 parts of Radix Ophiopogonis, 12 parts of Radix Dipsacis, 12 parts of the Radix Paeoniae Albas, 12 parts in Semen Persicae, 12 parts on Flos Carthami, 30 parts of Herba Leonuris, 3 parts in Radix Glycyrrhizae.
The manufacture method of externally used paste of the present invention is: above-mentioned each crude drug is proportionally taken by weighing, then, the crude drug that takes by weighing ground to form fine powder after, join in the substrate, fully stir, medicine is evenly distributed, make the semi-solid externally used paste with d spiss.
Above-mentioned fine powder is crossed sieve No. 9.
Above-mentioned substrate is any one in vaseline, liquid paraffin, silicone oil, Cera Flava, stearic acid, the lanoline.
The present invention has blood circulation promoting and blood stasis dispelling, anti-inflammation, and the toxin expelling of drawing out the pus promotes tissue regeneration, the effect of enhancing human body immunity power, short treating period, evident in efficacy, without any side effects, according to clinical 58 routine patients are observed statistics, use medicine effective percentage course for the treatment of effective percentage 95%, two course for the treatment of 99% of the present invention.
The specific embodiment
Embodiment one, 20 parts of Radix Angelicae Sinensis, 10 parts of Radix Rehmanniae Preparata, 10 parts of Radix Codonopsis, 10 parts of Radix Ophiopogonis, 10 parts of Radix Dipsacis, 10 parts of the Radix Paeoniae Albas, 10 parts in Semen Persicae, 10 parts on Flos Carthami, 25 parts of Herba Leonuris, 1 part in Radix Glycyrrhizae.
The manufacture method of externally used paste of the present invention is: above-mentioned each crude drug is proportionally taken by weighing, then, the crude drug that takes by weighing ground to form fine powder after, join in the substrate, fully stir, medicine is evenly distributed, make the semi-solid externally used paste with d spiss.
Embodiment two, 24 parts of Radix Angelicae Sinensis, 12 parts of Radix Rehmanniae Preparata, 15 parts of Radix Codonopsis, 12 parts of Radix Ophiopogonis, 12 parts of Radix Dipsacis, 12 parts of the Radix Paeoniae Albas, 12 parts in Semen Persicae, 12 parts on Flos Carthami, 30 parts of Herba Leonuris, 3 parts in Radix Glycyrrhizae.
The manufacture method of externally used paste of the present invention is: above-mentioned each crude drug is proportionally taken by weighing, then, the crude drug that takes by weighing ground to form fine powder after, join in the substrate, fully stir, medicine is evenly distributed, make the semi-solid externally used paste with d spiss.
Embodiment three, 30 parts of Radix Angelicae Sinensis, 15 parts of Radix Rehmanniae Preparata, 20 parts of Radix Codonopsis, 15 parts of Radix Ophiopogonis, 15 parts of Radix Dipsacis, 15 parts of the Radix Paeoniae Albas, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 40 parts of Herba Leonuris, 5 parts in Radix Glycyrrhizae.
The manufacture method of externally used paste of the present invention is: above-mentioned each crude drug is proportionally taken by weighing, then, the crude drug that takes by weighing ground to form fine powder after, join in the substrate, fully stir, medicine is evenly distributed, make the semi-solid externally used paste with d spiss.
The using method of externally used paste of the present invention is: externally used paste of the present invention is spread upon the patient wound, then, get final product with the gauze covering.Three days once, and three days is a course for the treatment of.
Be to use the statistics of unguentum of the present invention below:
One, physical data
Be selected from case 58 examples of disruption of wound behind my institute in January, the 2005-2011 year December cesarean section, all adopt abdominal transverse incision low-segment cesarean section formula, 21-37 years old ages, 26.8 years old mean age.
Two, observation index
3-9 days cut out portion of postoperative or all split reach theca of rectus abdominis muscle deeply or subcutaneous fat is liquefied as cavity, and blood, purulent secretion are arranged in the otch.
Three, Therapeutic Method
Under strict sterilization with otch in liquid feed extruding clean, and use normal saline washing, on otch, evenly smear medicine unguentum of the present invention then, get final product by immobilization with adhesive tape with the gauze covering.Changed medicine in three days one time.
Four, therapeutic outcome statistics
Figure 2012103360902100002DEST_PATH_IMAGE001
Effective percentage=healing rate+improvement rate.

Claims (2)

1. externally used paste that promotes wound healing behind the cesarean section is characterized in that this unguentum is made up of following bulk drugs: 20-30 parts of Radix Angelicae Sinensis, 10-15 parts of Radix Rehmanniae Preparata, 10-20 parts of Radix Codonopsis, 10-15 parts of Radix Ophiopogonis, 10-15 parts of Radix Dipsacis, 10-15 parts of the Radix Paeoniae Albas, 10-15 parts in Semen Persicae, 10-15 parts on Flos Carthami, 25-40 parts of Herba Leonuris, 1-5 parts in Radix Glycyrrhizae.
2. the externally used paste of wound healing behind the promotion cesarean section according to claim 1 is characterized in that this unguentum is made up of following bulk drugs: 24 parts of Radix Angelicae Sinensis, 12 parts of Radix Rehmanniae Preparata, 15 parts of Radix Codonopsis, 12 parts of Radix Ophiopogonis, 12 parts of Radix Dipsacis, 12 parts of the Radix Paeoniae Albas, 12 parts in Semen Persicae, 12 parts on Flos Carthami, 30 parts of Herba Leonuris, 3 parts in Radix Glycyrrhizae.
CN 201210336090 2012-09-12 2012-09-12 External paste used for promoting postoperation wound healing of caesarean delivery Expired - Fee Related CN102813811B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103041017B (en) * 2013-01-15 2014-06-04 韦雄开 Traditional Chinese medicine preparation for treating functional uterine bleeding and preparation method thereof
CN104666650A (en) * 2015-02-05 2015-06-03 青岛市中心医院 Traditional Chinese medicine preparation for cesarean postoperative recovery and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679839A (en) * 2005-01-14 2005-10-12 王庆华 Postpartum recuring particle
CN101502625A (en) * 2009-03-26 2009-08-12 李留俊 Chinese medicine for treating women's postpartum syndrome and preparation method thereof
CN102139033A (en) * 2011-04-10 2011-08-03 许从玉 Chinese medicinal composition for treating skin wound of pregnant woman after cesarean section
CN102430034A (en) * 2011-12-06 2012-05-02 许从玉 Medicine composition for enhancing wound healing after cesarean section and applications

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679839A (en) * 2005-01-14 2005-10-12 王庆华 Postpartum recuring particle
CN101502625A (en) * 2009-03-26 2009-08-12 李留俊 Chinese medicine for treating women's postpartum syndrome and preparation method thereof
CN102139033A (en) * 2011-04-10 2011-08-03 许从玉 Chinese medicinal composition for treating skin wound of pregnant woman after cesarean section
CN102430034A (en) * 2011-12-06 2012-05-02 许从玉 Medicine composition for enhancing wound healing after cesarean section and applications

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