CN104815245A - TCM (Traditional Chinese Medicine) composition for treating acne - Google Patents
TCM (Traditional Chinese Medicine) composition for treating acne Download PDFInfo
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- CN104815245A CN104815245A CN201510205779.5A CN201510205779A CN104815245A CN 104815245 A CN104815245 A CN 104815245A CN 201510205779 A CN201510205779 A CN 201510205779A CN 104815245 A CN104815245 A CN 104815245A
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Abstract
The invention provides a TCM (Traditional Chinese Medicine) composition for treating acne. In order to achieve an aim, the TCM composition is characterized in that active ingredients contained by the TCM composition are prepared by the following raw material medicines in parts by weight: phyllanthus urinaria, arundina graminifolia, schizonepeta, honeysuckle and the like, and a tincture is prepared by adopting a corresponding preparation method. The TCM composition has an effect of treating the cane.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition of Acne treatment and method for making and application.
Background technology
Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, and clinical manifestation is to be apt to occur in the pleomorphism skin lesion such as acne, pimple, pustule, tuberosity of face for feature.The factors such as the generation of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.Existing market is badly in need of a kind of medicine for external use of Acne treatment.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation of Acne treatment.
Another object of the present invention is the Chinese medicine preparation preparation method and application providing a kind of Acne treatment.
Technical scheme: the object of the invention is by following scheme realize:
A Chinese medicine composition for Acne treatment, the active component contained by it is extracted by following raw materials in part by weight medicine proportioning and is prepared from: Herba Thesii Longifolii 20 parts, Herba Murdanniae Divergentis 10 parts, Herba Schizonepetae 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 10 parts, Rhizoma Smilacis Glabrae 15 parts, Fructus Gardeniae 10 parts, Herba Taraxaci 15 parts, Semen Coicis 15 parts, Rhizoma Dioscoreae 15 parts, Cortex Mori 10 parts, Flos Chrysanthemi 10 parts, Bulbus Fritillariae Uninbracteatae 10 parts, Fructus Crataegi 15 parts, Fructus Mori 15 parts, Herba Scutellariae Barbatae 15 parts, Cacumen Platycladi 10 parts, Radix Scutellariae 10 parts, 10 parts, the Radix Rehmanniae, Radix Scrophulariae 10 parts.
The Chinese medicine composition of above-mentioned Acne treatment, described crude drug adds substrate and makes tincture after extracting.
The Chinese medicine composition of above-mentioned Acne treatment, described substrate is 75% ethanol 50-70 part.
The method of the Chinese medicine composition of above-mentioned Acne treatment, preparation process is: get above-mentioned medical material and merge, pulverize, make solvent soaking, get supernatant, be prepared into tincture, fill after 5-20 hour with 75% ethanol.
The preparation method of the Chinese medicine composition of above-mentioned Acne treatment, makes solvent soaking 10 hours with 75% ethanol in step.
The Chinese medicine composition of above-mentioned Acne treatment is preparing the application in Retinoids, Retin-A, Renova, Accutane.
Herba Thesii Longifolii is that Santalaceae plant comes into leaves the herb of Herba Thesii, and perennial herb, height is 50cm about.Stem clusters, and has obvious longitudinal furrow.Leaf stockless.Linear, long 4-4.5cm, wide 2.5mm, two ends are gradually sharp, have 3 arteries and veins.Expelling wind and clearing away heat, spasmolytic.
Herba Murdanniae Divergentis, Classification system Arundina graminifolia, the orchid family section, tree orchid race, Folium Bambusae Cymbidium, nature and flavor are bitter, flat.Heat-clearing and toxic substances removing, expelling wind and removing dampness, pain relieving, diuresis.For hepatitis, arthralgia, pain in the low back and legs, stomachache, stranguria, difficulty and pain in micturition, beriberi edema, scrofula, pulmonary tuberculosis, toothache, throat pain, flu, infantile convulsion, infantile malnutrition, cough, alimentary toxicosis, gets injured by a fall, venom, traumatic hemorrhage.The present invention is with all herbal medicine.All the other are pharmacopeia kind.
Found by clinical and experimental study, Chinese medicine composition of the present invention has good Acne treatment effect.Therefore, present invention also offers the purposes of aforementioned pharmaceutical compositions, namely the Chinese medicine composition of above-mentioned Acne treatment is preparing the application in Retinoids, Retin-A, Renova, Accutane.
Beneficial effect:
From theory of Chinese medical science, in we, heat-clearing and toxic substances removing, dampness removing promote the production of body fluid, and are used for the treatment of acne.Formulation is reasonable, and compatibility is rigorous.The present invention consists of Chinese crude drug, has no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, in conjunction with detailed description of the invention, the present invention is further described as follows:
Embodiment 1: get Herba Thesii Longifolii 20g, Herba Murdanniae Divergentis 10g, Herba Schizonepetae 10g, Flos Lonicerae 15g, Fructus Forsythiae 10g, Rhizoma Smilacis Glabrae 15g, Fructus Gardeniae 10g, Herba Taraxaci 15g, Semen Coicis 15g, Rhizoma Dioscoreae 15g, Cortex Mori 10g, Flos Chrysanthemi 10g, Bulbus Fritillariae Uninbracteatae 10g, Fructus Crataegi 15g, Fructus Mori 15g, Herba Scutellariae Barbatae 15g, Cacumen Platycladi 10g, Radix Scutellariae 10g, Radix Rehmanniae 10g, the merging of Radix Scrophulariae 10g medical material, pulverize, solvent soaking is made with 75% ethanol 60 parts, supernatant is got, fill after 10 hours.
2, clinical observation and model case:
Physical data: all 13 ~ 32 years old case ages, 21.4 years old mean age, the course of disease 3 months-3 years, average course of disease 2.5 years.Totally 100 examples, adopt random number method, patient are divided into two groups at random, treatment group 50 example: wherein man 25 example, female 25 example, by acne classification level Four improvement staging, and point I level acne 12 example, II level acne 38 example; Matched group 50 example: wherein man 22 example, female 28 example, I level acne 24 example, II level acne 24 example.Through statistical analysis, above two groups of cases are in sex, age, the state of an illness, and no significant difference (P > 0.05), has comparability.
Diagnostic criteria: (1) diagnosis is with reference to " clinical dermatology ", " People's Republic of China's traditional Chinese medicine industry standard-TCM Dermatology disease Standardization of diagnosis and curative effect ": have typical clinical symptoms and sign, skin lesion is mainly being dispersed in property blackhead, inflamed papules, pustule, tuberosity, the cyst of involving facial area, is diagnosed as acne person.(2) exclusion standard: 1. with infectious disease person, as: hepatitis, syphilis, acquired immune deficiency syndrome (AIDS) etc.; 2. can not chronotherapeutic person on demand; 3. the person that accepts other treatment in therapeutic process.
Therapeutic Method: treatment group uses traditional Chinese medicinal lotion of the present invention, washout potion every day, three times on the one; Matched group only gives the external of clindamycin and metronidazole liniment, every day 2 times.Two groups of homogeneous Zhou Weiyi courses for the treatment of.
Criterion of therapeutical effect: formulate " Chinese medicine (new drug) guideline of clinical investigations " with reference to Ministry of Health of the People's Republic of China: recovery from illness: facial acne erythra all disappears, and occurs, only stay pigmentation without new breakout; Effective: acne deflorescence more than 70%, inflammation obviously alleviates, and occurs without new erythra; Effective: acne erythra obviously disappears 20%-70%, there is a small amount of new erythra to occur; Invalid: acne erythra obviously disappears 20%, or still have new erythra to occur.
Therapeutic outcome: add up curative effect after treating two courses for the treatment of, treatment group 50 example, 28 examples of wherein fully recovering, effective 14 examples, effective 6 examples, invalid 2 examples, total effective rate arrives 96%; Matched group 50 example, 8 examples of wherein fully recovering, effective 10 examples, effective 5 examples, invalid 27 examples, effective percentage reaches 46%.Two groups of cure rates, total effective rate has significant difference (P < 0.05).
Claims (5)
1. the Chinese medicine composition of an Acne treatment, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine proportioning and is prepared from: Herba Thesii Longifolii 20 parts, Herba Murdanniae Divergentis 10 parts, Herba Schizonepetae 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 10 parts, Rhizoma Smilacis Glabrae 15 parts, Fructus Gardeniae 10 parts, Herba Taraxaci 15 parts, Semen Coicis 15 parts, Rhizoma Dioscoreae 15 parts, Cortex Mori 10 parts, Flos Chrysanthemi 10 parts, Bulbus Fritillariae Uninbracteatae 10 parts, Fructus Crataegi 15 parts, Fructus Mori 15 parts, Herba Scutellariae Barbatae 15 parts, Cacumen Platycladi 10 parts, Radix Scutellariae 10 parts, 10 parts, the Radix Rehmanniae, Radix Scrophulariae 10 parts.
2. the Chinese medicine composition of Acne treatment as claimed in claim 1, is characterized in that, described crude drug makes tincture through soaking with substrate, and described substrate is 75% ethanol 50-70 part.
3. the Chinese medicine composition of Acne treatment as claimed in claim 1, is characterized in that, preparation method comprises the steps: that getting above-mentioned medical material merges, and pulverizes, makes solvent soaking, get supernatant, be prepared into tincture, fill after 5-20 hour with 75% ethanol.
4. the Chinese medicine composition of Acne treatment according to claim 4, is characterized in that making solvent soaking 10 hours with 75% ethanol in preparation method step.
5. the application of the Chinese medicine composition of Acne treatment in Retinoids, Retin-A, Renova, Accutane as claimed in claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510205779.5A CN104815245A (en) | 2015-04-28 | 2015-04-28 | TCM (Traditional Chinese Medicine) composition for treating acne |
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| CN201510205779.5A CN104815245A (en) | 2015-04-28 | 2015-04-28 | TCM (Traditional Chinese Medicine) composition for treating acne |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114767772A (en) * | 2022-05-25 | 2022-07-22 | 云南中医药大学 | A pharmaceutical composition for treating acne |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199703A (en) * | 2007-12-12 | 2008-06-18 | 叶志军 | Tincture medicament for treating acne |
| CN103908558A (en) * | 2014-04-22 | 2014-07-09 | 福州永同惠生物医药科技有限公司 | Traditional Chinese medicine composition for treating acne and preparation method and application thereof |
| CN104001059A (en) * | 2014-06-11 | 2014-08-27 | 徐艳 | Traditional Chinese medicine composition for treating acnes and preparation method and application thereof |
-
2015
- 2015-04-28 CN CN201510205779.5A patent/CN104815245A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199703A (en) * | 2007-12-12 | 2008-06-18 | 叶志军 | Tincture medicament for treating acne |
| CN103908558A (en) * | 2014-04-22 | 2014-07-09 | 福州永同惠生物医药科技有限公司 | Traditional Chinese medicine composition for treating acne and preparation method and application thereof |
| CN104001059A (en) * | 2014-06-11 | 2014-08-27 | 徐艳 | Traditional Chinese medicine composition for treating acnes and preparation method and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114767772A (en) * | 2022-05-25 | 2022-07-22 | 云南中医药大学 | A pharmaceutical composition for treating acne |
| CN114767772B (en) * | 2022-05-25 | 2023-09-22 | 云南中医药大学 | Pharmaceutical composition for treating acne |
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Application publication date: 20150805 |
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