CN104984265A - Traditional Chinese medicine preparation for cutaneous hemangioma and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for cutaneous hemangioma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for cutaneous hemangioma and belongs to the invention field of traditional Chinese medicine. The traditional Chinese medicine preparation for cutaneous hemangioma comprises radix actinidiae chinensis, glabrous greenbrier rhizome, dandelion, olibanum, myrrh, radix paeoniae alba, spina gleditsiae, alga, kelp, rhizoma pinelliae, tangerine peels, prunella vulgaris, pericarpium citri reticulatae viride, atractylodes, cortex magnoliae officinalis, cortex dictamni, raw coix seeds, peach kernels, fructus polygoni orientalis, spreading hedyotis herbs, salvia chinensis, rhizoma paridis, rhizoma menipermi extracts, fructus psoraleae, fructus psoraleae, rhizoma sparganii and rhizoma curcumae. According to different characteristics of all the traditional Chinese medicine, all the raw materials are cleaned, cut into pieces, pretreated, blended in proportion and manufactured into the traditional Chinese medicine preparation for cutaneous hemangioma through the special method. The traditional Chinese medicine preparation for cutaneous hemangioma has the effects of activating blood to promote menstruation, promoting qi circulation, relieving pain, clearing heat, conducting detoxification, eliminating dampness and removing stasis. The combination and manufacturing method is unique; it is proved in clinical trials that the preparation for cutaneous hemangioma is remarkable in curative effect, short in treatment cycle and low in price, has no adverse effect and no toxic and side effect and has broad market application prospects.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for cutaneous hemangioma, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Cutaneous hemangioma, originates from mesoderm, is the benign tumor of congenital capillary proliferation expansion, how to occur soon at birth or after birth.Minority childhood period or adult age start morbidity.Increasing with the age, stopping development to growing up.Most infringement head, skin of neck, but the places such as mucosa, liver, lower limb and muscle also can occur.At infancy stage rapid development, stop growing gradually later, disappear voluntarily sometimes.This tumor, in growth course, can cause some complication, can cause bleeding or ulcer, arteriovenous fistula and thrombocytopenia etc. as wound or when infecting.
Chinese medicine is thought, heart governing blood and vessels, the spleen governs the blood, blood stored in the liver, kidney storing essence, and essence and blood can change life mutually.Angioma morbidity is many and pathogenic fire is closely related for suffering from.
At present, cutaneous hemangioma there is no specific short.Conventional sclerosing agent is 5% morrhuic acid sodium solution or 1% ~ 10% salicylate solution, is injected in bottom hemangioma, has certain curative effect 1 time weekly or every other week.Conditions of patients seriously even adopts excision and radiation therapy method.But the long-term or short time uses these medicines to treat, the rising of obesity, hirsutism, blood glucose, vomiting, constipation etc. series of side effects symptom can be caused, after drug withdrawal, primary affection knock-on increases the weight of the side effect with secondary, patient can be made to produce very large misery, therapeutic process again and again, DeGrain, expense is high, causes larger pressure at heart and ailing pressure to patient.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for cutaneous hemangioma, it is remarkable that this Chinese medicine preparation has therapeutic effect for treatment cutaneous hemangioma, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of cutaneous hemangioma repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
Rhizoma Smilacis Glabrae: be the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..Nature and flavor: sweet, light are flat.Return liver, stomach warp.Effect: dehumidifying, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.Record in " book on Chinese herbal medicine just ": treat carbuncle, sore throat, except the whole body cold-damp, malignant boil.
Herba Taraxaci: be feverfew Herba Taraxaci Taraxacum mongolicum Hand.-Mazz., alkali ground Herba Taraxaci Taraxacum sinicum Kitag. or the dry herb belonging to several plants together.Spend spring to autumn when just opening and excavate, removing impurity, cleans, dries.Nature and flavor: bitter, sweet, cold.Return liver, stomach warp.Cure mainly heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Olibanum: be Burseraceae Boswellia carterii platymiscium Boswellia carterii Boswellia carterii Birdw. [B. sacra Fluek.], medicine glue XIANGSHU B. bhawdajiana Birdw. and wild Boswellia carterii B. neglecta M. Moore etc., the oleo-gum-resin that its trunk skin zone wound oozes out.Nature and flavor: pungent, bitter, temperature.Effect: promoting blood circulation and stopping pain.For all pains of trusted subordinate, the contracture of muscle arteries and veins, traumatic injury, sore, carbuncle and painful swelling; Externally used detumescence granulation promoting.Record in " detailed outline ": all poison of eliminating carbuncle cellulitis, the heart is protected in Tuoli, and analgesic therapy of invigorating blood circulation, stretches muscle, controls married woman's difficult labour, injured.
Myrrha: the oleo-gum-resin of oozing out for Burseraceae bdellium plant myrrh Commiphora myrrha Engl. [C. molmol Engl.] and the trunk skin zone that belongs to his kind of plant together.Nature and flavor: bitter, pungent are flat.Return spleen, kidney, liver, heart channel.Effect: loose blood blood stasis removing, subduing swelling and relieving pain.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: bitter, sour, are slightly cold.Return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Record in " herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return liver, stomach warp.Effect: detumescence poison holding, evacuation of pus, parasite killing.For carbuncle from the beginning of or difficulty in discharging of pus; External treatment scabies leprosy.Record in " detailed outline ": control carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing.
Sargassum: be the dry frond of Sargassaceae plant Sargassum Sargassum pallidum (Turn.) C. Ag. or Sargassum fusiforme (Harv.) Setch Sargassum fusiforme (Harv.) Setch..Nature and flavor: bitter, salty, cold.Return liver, stomach, kidney channel.Effect: hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.Record in " not Lu ": treat between skin and gather, sudden and violent Huang, stays gas, accumulation of heat, diuresis.
The Rhizoma Pinelliae: be the dry tuber of aroid Rhizoma Pinelliae Pinellia ternata (Thunb.) Breit..Nature and flavor: pungent, temperature; Poisonous.Return spleen, stomach, lung meridian.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.Nature and flavor: bitter, pungent, temperature.Return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Spica Prunellae: be the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..Nature and flavor: pungent, bitter, cold.Return liver, gallbladder meridian.Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.Record in " herbal classic ": main cold and heat, scrofula, scrofula, head sore, broken disease, loose wart stagnation of QI, swelling of the feet arthralgia chiefly caused by damp pathogen.
Pericarpium Citri Reticulatae Viride: be rutaceae orange Citrus reticulata Blanco and the dry young fruit of variety thereof or the peel of immature fruit.Nature and flavor: bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Effect: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.Record in essentials of Matea Medica: expectorant disappears painful abdominal mass, controls depression of liver-QI, the many anger of hypochondriac pain, chronic malaria knot addiction, colic, swelling of the breast.
Rhizoma Atractylodis: be the dry rhizome of feverfew Atractylodes lancea (Thunb.) DC. Atractylodes lancea (Thunb.) DC. or Atractylis chinensis Atractylodes chinensis (DC.) Koidz..Nature and flavor: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Effect: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.Record in " beautiful Chinese catalpa medicine solution ": dry native diuretic, let out drink expectorant, clots absorbing, dissipating depression of QI, go Lou, change addiction, except disease, reason acid regurgitation removing the necrotic tissue, ward off mountains and rivers communicable subtropical diseases, the flaccidity returning muscles and bones is soft, excessive muddiness of urinating clearly.
Cortex Magnoliae Officinalis: be the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis Magnolia officinalis Rehd. et Wils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils., root bark and branch skin.Nature and flavor: bitter, pungent, temperature.Return spleen, stomach, lung, large intestine channel.Effect: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.Record in " herbal classic ": main apoplexy typhoid fever, headache, cold and heat are palpitated with fear, and QI and blood numbness, dead flesh, goes three worms.
Semen Coicis: be the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.Nature and flavor: sweet, light, cool.Return spleen, stomach, lung meridian.Effect: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.Record in " detailed outline ": invigorating spleen and reinforcing stomach, tonifying the lung heat clearing away, removes wind prevailing over dampness.To cook a meal food, control cold air; Decoct drink, diuresis pyretic stranguria.
Semen Persicae: be the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Record in " herbal classic ": main blood stasis, blood closes lump in the abdomen, pathogen, kills small worm." not Lu ": only cough with dyspnea, disappear hardness in the epigastrium, and except soldier hits blood cruelly, broken lump in the abdomen, promotes blood circulation, pain relieving.
Herba Hedyotidis Diffusae: be the herb of Rubiaceae plants of Hedyotis Herba Hedyotidis Diffusae Hedyotis diffusa Willd. [Oldenlandia diffusa (Willd.) Roxb.].Nature and flavor: sweet, light, cool.Be included into stomach, large intestine, small intestine meridian.Effect: heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria; Furuncle carbuncle is controlled in external, venom.Record in " Quanzhou book on Chinese herbal medicine ": heat clearing away dissipating blood stasis, eliminating carbuncle detoxifies.Control ulcer sores, scrofula.Again can lung heat clearing fire, eliminating the pathogens from the lung heat.Control lung-heat dyspnea with rapid and short breath, cough against uncomfortable in chest.
Rhizoma Paridis: (Rhizoma Paridis) is Liliaceae paris plant China Rhizoma Paridis Paris polyphylla Smith var. chinenisi (Franch) Hara, Rhizoma Paridis Paris polyphylla Smith var. yunnanensis (Franch.) Hand.-Mazz. or Rhizoma Paridis Paris polyphylla Smith var, the dry rhizome of chinensis (Franch.) Hara.Nature and flavor: bitter, are slightly cold; Slightly poisonous.Return Liver Channel.Effect: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion.For furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, convulsion with spasms.
Rhizoma Menispermi: be the dry rhizome of menispermaceous plants Caulis menispermi Menispermum dauricum DC..Nature and flavor: bitter, cold, slightly poisonous.Return lung, stomach, large intestine channel.Effect: heat-clearing and toxic substances removing, wind-expelling pain-stopping.For laryngopharynx swelling and pain, enteritis and dysentery, rheumatic arthralgia.
Fructus Psoraleae: be the dry mature fruit of legumes psoraleae Psoralea corylifolia L..Nature and flavor: pungent, bitter, temperature.Return kidney, spleen channel.Effect: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.Record in " beautiful Chinese catalpa medicine solution ": warm water and soil, digestion diet, rises and reaches taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards.
Rhizoma Sparganii: be the dry tuber of Sparganiaceae plant rhizoma scirpi Sparganium stoloniferum Buch.-Ham..Nature and flavor: pungent, bitter are flat.Return liver, spleen channel.Effect: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.Record in " Japan hanako materia medica ": control married woman's blood vessels uncomfortable, cardiac and abdominal pain, fall tire, and disappear stagnant blood, mend labor, logical menstruation, controls flatulence, disappears and flutter damage blood stasis, puerperal abdonimal pain, blood fortune stagnated blood not under.
Rhizoma Curcumae: be the dry rhizome of zingiberaceous plant Rhizoma Curcumae Curcuma phaeocaulis Val., Guangxi zedoary Curcuma Kwangsiensis S. G.Lee et C. F. Liang or RADIX CURCUMAE Curcuma wenyujin Y.H. Chen et C. Ling.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.
Radix Actinidiae Chinensis: be the root of Fructus actinidiae chinensis section plant Fructus actinidiae chinensis.Nature and flavor: sour, puckery, cool.Effect: heat-clearing and toxic substances removing, expelling wind and removing dampness, diuresis is stopped blooding.For rheumatic ostalgia, and the disease such as jaundice.
Thallus Laminariae (Thallus Eckloniae): be the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) Laminaria japonica Aresch. or Alariaceae plant Thallus Laminariae (Thallus Eckloniae) (goose palm dish) Ecklonia kurome Okam..Nature and flavor: salty, cold.Gui Jing: return liver, stomach, kidney channel.Effect: hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.Record in " property of medicine opinion ": dredging water passages, remove swelling of the face, remove malignant boil scrofula.
Cortex Dictamni: be the dry root bark of rutaceae shaggy-fruited dittany Dictamnus dasycarpus Turcz..Nature and flavor: bitter, cold.Return spleen, stomach, urinary bladder channel.Effect: heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.Record in " property of medicine opinion ": control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red rotten, and eyebrow loss of hairs is crisp, musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat is yellow, wine is yellow, acute jaundice, paddy Huang, labor are yellow.
Fructus Polygoni Orientalis: be the dry mature fruit of polygonaceae plant smartweed Polygonum orientale L..Extract fruit ear during fruit maturation in autumn, dry, lay fruit, removing impurity.Nature and flavor: salty, are slightly cold.Return liver, stomach warp.Effect: loose blood eliminating mass, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, goiter swells and ache, and food stagnation does not disappear, epigastric distending pain.Record in " pharmacognosy ": removing heat from the lung and dissipating phlegm, sending down the abnormal ascending QI relieving constipation, rash.Control phlegmatic cough to breath with cough, defecation is unfavorable, measles without adequate eruption.
Herba Salviae Chinensis: be Lamiaceae Salvia platymiscium Herba Salviae Chinensis Salvia chinensia Benth., with all herbal medicine.Florescence taps herb, dries.Nature and flavor: micro-hardship are flat.Effect: heat-clearing and toxic substances removing, invigorating blood circulation analgesia.For icterohepatitis, cancer, nephritis, leucorrhea, dysmenorrhea, tuberculous lymphadenitis, elephantiasis; Facial paralysis is controlled in external, mastitis, furuncle and phyma.Record in " detailed outline ": main osteodynia, strong wind, carbuncle.
Side's solution of the present invention is: Olibanum promoting blood circulation and stopping pain, Myrrha falls apart blood blood stasis removing, subduing swelling and relieving pain, Radix Paeoniae Alba nourishing blood for regulating menstruation, Pericarpium Citri Reticulatae Viride is soothing the liver dispelling the stagnated QI, removing food stagnancyization are stagnant, Semen Persicae blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, Fructus Polygoni Orientalis falls apart blood eliminating mass, removing food stagnancy pain relieving, the circulation of qi promoting of Rhizoma Sparganii removing blood stasis, removing food stagnancy pain relieving, Rhizoma Curcumae circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving, above eight taste medicines are as monarch drug in side, all return Liver Channel, there is the effect of promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain.Chinese medicine is thought, primary disease is invaded outside the many evil poison of the formation of disease, and interior volt blood system, causes the impaired stasis of blood of channels stagnant and cause primary disease.So promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain are bases for the treatment of cutaneous hemangioma, above eight taste medicines are monarch drug, and first fundamentally promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain make disease obtain basic control.Radix Actinidiae Chinensis heat-clearing and toxic substances removing, expelling wind and removing dampness, Thallus Laminariae (Thallus Eckloniae) hard masses softening and resolving, expectorant diuretic, Rhizoma Smilacis Glabrae removing dampness and detoxicating, Herba Taraxaci heat-clearing and toxic substances removing, Spica Prunellae relieves inflammation or internal heat eliminating stagnation, Cortex Dictamni heat clearing and damp drying, removing toxic substances of dispeling the wind, Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, Herba Salviae Chinensis heat-clearing and toxic substances removing, Rhizoma Paridis heat-clearing and toxic substances removing, reducing swelling and alleviating pain, Rhizoma Menispermi heat-clearing and toxic substances removing, wind-expelling pain-stopping, Spina Gleditsiae detumescence poison holding, Sargassum hard masses softening and resolving, expectorant diuretic, ministerial drug in the above 12 taste medicine sides of being, on the one hand effect of auxiliary monarch drug promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain; There is as ministerial drug effect of heat-clearing and toxic substances removing, dehumidifying eliminating stagnation on the other hand.Rhizoma Pinelliae drying dampness to eliminate phlegm, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Rhizoma Atractylodis are drying damp and strengthening spleen, expelling wind and cold, the expectorant of Cortex Magnoliae Officinalis dampness, the therapeutic method to keep the adverse QI flowing downwards are except full, and row is dense for Semen Coicis spleen invigorating eliminating dampness by diuresis, heat clearing away, Fructus Psoraleae warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI antidiarrheal, above Six-element medicine is as adjuvant drug, cause the inducement of cutaneous hemangioma from pathology treatment, the promoting blood flow to regulate menstruation of the monarch and his subjects two medicine, effect of promoting the circulation of QI to relieve pain can be promoted as adjuvant drug, the effect of body heat-clearing and toxic substances removing, dehumidifying eliminating stagnation can be promoted by using corrigent the monarch and his subjects two medicine again.As having, spleen invigorating is regulated the flow of vital energy, effect of expelling wind and cold simultaneously.The all medicines of this side share, and the monarch and his subjects pull together, and minister assistant is auxiliary altogether, has effect of promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain, heat-clearing and toxic substances removing, dehumidifying eliminating stagnation, effectively can treat cutaneous hemangioma.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Actinidiae Chinensis 18-22g, Rhizoma Smilacis Glabrae 28-32g, Herba Taraxaci 16-20g, Olibanum 8-12g, Myrrha 7-11g, Radix Paeoniae Alba 10-14g, Spina Gleditsiae 22-26g, Sargassum 18-22g, Thallus Laminariae (Thallus Eckloniae) 18-22g, Rhizoma Pinelliae 13-17g, Pericarpium Citri Reticulatae 13-17g, Spica Prunellae 22-26g, Pericarpium Citri Reticulatae Viride 10-14g, Rhizoma Atractylodis 13-17g, Cortex Magnoliae Officinalis 13-17g, Cortex Dictamni 13-17g, Semen Coicis 28-32g, Semen Persicae 10-14g, Fructus Polygoni Orientalis 13-17g, Herba Hedyotidis Diffusae 22-26g, Herba Salviae Chinensis 13-17g, Rhizoma Paridis 13-17g, Rhizoma Menispermi 10-14g, Fructus Psoraleae 16-20g, Rhizoma Sparganii 13-17g, Rhizoma Curcumae 13-17g.
Wherein be preferably: Radix Actinidiae Chinensis 20g, Rhizoma Smilacis Glabrae 30g, Herba Taraxaci 18g, Olibanum 10g, Myrrha 9g, Radix Paeoniae Alba 12g, Spina Gleditsiae 24g, Sargassum 20g, Thallus Laminariae (Thallus Eckloniae) 20g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 15g, Spica Prunellae 24g, Pericarpium Citri Reticulatae Viride 12g, Rhizoma Atractylodis 15g, Cortex Magnoliae Officinalis 15g, Cortex Dictamni 15g, Semen Coicis 30g, Semen Persicae 12g, Fructus Polygoni Orientalis 15g, Herba Hedyotidis Diffusae 24g, Herba Salviae Chinensis 15g, Rhizoma Paridis 15g, Rhizoma Menispermi 12g, Fructus Psoraleae 18g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g.
A kind of preparation method of the Chinese medicine preparation for cutaneous hemangioma is as follows:
Step one: by weight of the present invention, gets Olibanum, Myrrha, pulverizes, and crosses 200 mesh sieves, for subsequent use;
Step 2: by weight of the present invention, get the Rhizoma Pinelliae, Rhizoma Paridis, Rhizoma Menispermi medical material be placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, lard speech with literary allusions fiery infusion 30-40 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use;
Step 3: by weight proportion of the present invention, get Radix Actinidiae Chinensis, Rhizoma Smilacis Glabrae, the Radix Paeoniae Alba, Spina Gleditsiae, Cortex Dictamni, Rhizoma Sparganii, Rhizoma Curcumae medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Pericarpium Citri Reticulatae, Spica Prunellae, Pericarpium Citri Reticulatae Viride, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Herba Hedyotidis Diffusae, Herba Salviae Chinensis, Fructus Psoraleae and the Semen Coicis tied with bundle respectively, Semen Persicae, Fructus Polygoni Orientalis, Sargassum, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use;
Step 4: combining step two, step 3 gained filtrate are taken after mixing it with water step one gained powder while hot, mixing, stir evenly, medicine soup is carried out concentrate and add ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, it is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment by gained concentration of liquid medicine, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 0.5g, both the pill for the treatment of cutaneous hemangioma of the present invention.
Using method of the present invention: get pill, in one hour after meal, warm water is taken after mixing it with water, each one bag, every day three times.
Medicine of the present invention has the effect of promoting blood flow to regulate menstruation, promoting the circulation of QI to relieve pain, heat-clearing and toxic substances removing, dehumidifying eliminating stagnation, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviate the slight illness of patient, according to clinical 60 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 83.3%, two the total effective rate course for the treatment of 93.4%.
Detailed description of the invention
Embodiment one: Radix Actinidiae Chinensis 20g, Rhizoma Smilacis Glabrae 30g, Herba Taraxaci 18g, Olibanum 10g, Myrrha 9g, Radix Paeoniae Alba 12g, Spina Gleditsiae 24g, Sargassum 20g, Thallus Laminariae (Thallus Eckloniae) 20g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 15g, Spica Prunellae 24g, Pericarpium Citri Reticulatae Viride 12g, Rhizoma Atractylodis 15g, Cortex Magnoliae Officinalis 15g, Cortex Dictamni 15g, Semen Coicis 30g, Semen Persicae 12g, Fructus Polygoni Orientalis 15g, Herba Hedyotidis Diffusae 24g, Herba Salviae Chinensis 15g, Rhizoma Paridis 15g, Rhizoma Menispermi 12g, Fructus Psoraleae 18g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g.
Embodiment two: Radix Actinidiae Chinensis 21g, Rhizoma Smilacis Glabrae 31g, Herba Taraxaci 17g, Olibanum 11g, Myrrha 9g, Radix Paeoniae Alba 11g, Spina Gleditsiae 23g, Sargassum 21g, Thallus Laminariae (Thallus Eckloniae) 21g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 15g, Spica Prunellae 23g, Pericarpium Citri Reticulatae Viride 12g, Rhizoma Atractylodis 15g, Cortex Magnoliae Officinalis 15g, Cortex Dictamni 15g, Semen Coicis 30g, Semen Persicae 11g, Fructus Polygoni Orientalis 13g, Herba Hedyotidis Diffusae 23g, Herba Salviae Chinensis 13g, Rhizoma Paridis 13g, Rhizoma Menispermi 11g, Fructus Psoraleae 17g, Rhizoma Sparganii 15g, Rhizoma Curcumae 14g.
Embodiment three: Radix Actinidiae Chinensis 21g, Rhizoma Smilacis Glabrae 31g, Herba Taraxaci 18g, Olibanum 10g, Myrrha 9g, Radix Paeoniae Alba 11g, Spina Gleditsiae 23g, Sargassum 21g, Thallus Laminariae (Thallus Eckloniae) 20g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 15g, Spica Prunellae 23g, Pericarpium Citri Reticulatae Viride 11g, Rhizoma Atractylodis 15g, Cortex Magnoliae Officinalis 15g, Cortex Dictamni 15g, Semen Coicis 30g, Semen Persicae 11g, Fructus Polygoni Orientalis 14g, Herba Hedyotidis Diffusae 24g, Herba Salviae Chinensis 14g, Rhizoma Paridis 14g, Rhizoma Menispermi 12g, Fructus Psoraleae 17g, Rhizoma Sparganii 14g, Rhizoma Curcumae 14g.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 60 example for medical treatment, patient is divided at random observation group and each 30 examples of matched group, wherein male 40 example, women 20 example, M-F 2:1, max age 6 years old, minimal ages 1 years old, course of disease some months is not by several years etc.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, diagnostic criteria
1, differ in size during birth or after birth cerise or mauve neoplasm soon;
2, various angiomatous skin lesion feature;
3, histopathology;
4, nevus flammeus: intradermal blood capillary proliferation and expansion;
5, hemangioma simplex: blood capillary and blood vessel endothelium hypertrophy in corium or subcutaneous tissue;
6, cavernous hemangioma: the lumen of vessels differed in size in corium and subcutaneous tissue, adventitial cell hypertrophy.
Three, Therapeutic Method:
1, observation group is according to Medications Example one of the present invention, and weighting raw materials, by the treatment of invention implementation method, is got pill, taken in one hour after meal, each one bag, every day three times.It within 7 days, is a course for the treatment of.
2, matched group adopts the treatment of regular injection 5% sodium morrhuate, within 7 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: skin lesion or tumor regression, do not cause local necrosis, leaves inapparent cicatrix;
2, take a turn for the better: skin lesion or tumor regression, alleviate the invasion and attack of other organs, platelet recovery is normal, and blood coagulation factor is normal;
3, invalid: skin lesion or tumor are without significant change, and platelet and blood coagulation factor are not corrected extremely, do not alleviate the invasion and attack of other organs or compressing.
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness in treatment cutaneous hemangioma, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, patient Lee, female, 3 years old, people from Qingdao City, came here and goes to a doctor on January 20th, 2010.Unilateral, scalp infringement, be initially not of uniform size or several light red, dark red patch, in irregular shape, clear border, does not exceed surface, partially or completely fading of pressure, surface smoothing.With age, color burn reddens, purpling.The focus of patient will be expanded gradually, be diagnosed as cutaneous hemangioma.Through treatment pain relief, but do not cure.Occur symptom again, here treatment then, adopts made preparation in the embodiment of the present invention one, and selected preparation method, and symptom goes down, and affected part recovers good, and continue medication 6 days, thoroughly cure, Effect of follow-up visit by telephone does not recur half a year.
Case two, patient Zhang, man, 4 years old, people from Linyi, Shandong.Come here on May 14th, 2010 to go to a doctor, head and face, damage as redness, and in flat, hemispherical, finger is large to egg greatly, clear border, and softness touched is like cavernous transformation, and that presses reduces, and goes to press rear recovery, can ulceration or secondary infection during increase.It is positive that lump position moves experiment, and right overhead during low level, tumor hyperemia is expanded; After new line, mass reduction and restoring to the original state.No conscious sympton, but during secondary infection, cause pain, ulcer, be diagnosed as cutaneous hemangioma.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, symptom goes down, and pain slightly alleviates, and affected part recovers good, and continue medication 5 days, thoroughly cure, Effect of follow-up visit by telephone does not recur half a year.
Claims (4)
1. the Chinese medicine preparation for cutaneous hemangioma, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Actinidiae Chinensis 18-22g, Rhizoma Smilacis Glabrae 28-32g, Herba Taraxaci 16-20g, Olibanum 8-12g, Myrrha 7-11g, Radix Paeoniae Alba 10-14g, Spina Gleditsiae 22-26g, Sargassum 18-22g, Thallus Laminariae (Thallus Eckloniae) 18-22g, Rhizoma Pinelliae 13-17g, Pericarpium Citri Reticulatae 13-17g, Spica Prunellae 22-26g, Pericarpium Citri Reticulatae Viride 10-14g, Rhizoma Atractylodis 13-17g, Cortex Magnoliae Officinalis 13-17g, Cortex Dictamni 13-17g, Semen Coicis 28-32g, Semen Persicae 10-14g, Fructus Polygoni Orientalis 13-17g, Herba Hedyotidis Diffusae 22-26g, Herba Salviae Chinensis 13-17g, Rhizoma Paridis 13-17g, Rhizoma Menispermi 10-14g, Fructus Psoraleae 16-20g, Rhizoma Sparganii 13-17g, Rhizoma Curcumae 13-17g.
2. the Chinese medicine preparation for cutaneous hemangioma according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Actinidiae Chinensis 20g, Rhizoma Smilacis Glabrae 30g, Herba Taraxaci 18g, Olibanum 10g, Myrrha 9g, Radix Paeoniae Alba 12g, Spina Gleditsiae 24g, Sargassum 20g, Thallus Laminariae (Thallus Eckloniae) 20g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 15g, Spica Prunellae 24g, Pericarpium Citri Reticulatae Viride 12g, Rhizoma Atractylodis 15g, Cortex Magnoliae Officinalis 15g, Cortex Dictamni 15g, Semen Coicis 30g, Semen Persicae 12g, Fructus Polygoni Orientalis 15g, Herba Hedyotidis Diffusae 24g, Herba Salviae Chinensis 15g, Rhizoma Paridis 15g, Rhizoma Menispermi 12g, Fructus Psoraleae 18g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g.
3. the Chinese medicine preparation for cutaneous hemangioma according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is pill.
4. for a preparation method for the Chinese medicine preparation of cutaneous hemangioma, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, gets Olibanum, Myrrha, pulverizes, and crosses 200 mesh sieves, for subsequent use; Step 2: by weight of the present invention, get the Rhizoma Pinelliae, Rhizoma Paridis, Rhizoma Menispermi medical material be placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, lard speech with literary allusions fiery infusion 30-40 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use; Step 3: by weight proportion of the present invention, get Radix Actinidiae Chinensis, Rhizoma Smilacis Glabrae, the Radix Paeoniae Alba, Spina Gleditsiae, Cortex Dictamni, Rhizoma Sparganii, Rhizoma Curcumae medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Pericarpium Citri Reticulatae, Spica Prunellae, Pericarpium Citri Reticulatae Viride, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Herba Hedyotidis Diffusae, Herba Salviae Chinensis, Fructus Psoraleae and the Semen Coicis tied with bundle respectively, Semen Persicae, Fructus Polygoni Orientalis, Sargassum, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 4: combining step two, step 3 gained filtrate are taken after mixing it with water step one gained powder while hot, mixing, stir evenly, medicine soup is carried out concentrate and add ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, it is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment by gained concentration of liquid medicine, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 0.5g, both the pill for the treatment of cutaneous hemangioma of the present invention.
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| CN108392517A (en) * | 2018-05-28 | 2018-08-14 | 湖北喜宝药业有限公司 | A kind of Chinese medicine preparation and preparation method thereof being used for hemangioma cutis and vascular malformation |
| CN109045243A (en) * | 2018-09-29 | 2018-12-21 | 湖北喜宝药业有限公司 | Chinese medicine composition, preparation and preparation method thereof for treating infant hemangioma |
| CN110433260A (en) * | 2019-08-23 | 2019-11-12 | 北京市中医研究所 | A kind of pharmaceutical composition and preparation method thereof for treating psoriasis |
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| CN102091290A (en) * | 2010-12-06 | 2011-06-15 | 济南金鼎信息技术有限公司 | Chinese medicine composition for treating cutaneous hemangioma |
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| CN108392517A (en) * | 2018-05-28 | 2018-08-14 | 湖北喜宝药业有限公司 | A kind of Chinese medicine preparation and preparation method thereof being used for hemangioma cutis and vascular malformation |
| CN109045243A (en) * | 2018-09-29 | 2018-12-21 | 湖北喜宝药业有限公司 | Chinese medicine composition, preparation and preparation method thereof for treating infant hemangioma |
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