CN105194547A - Chinese herba preparation for eosinophilic fasciitis and preparation method thereof - Google Patents
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Abstract
The invention discloses a Chinese herba preparation for eosinophilic fasciitis, and belongs to the field of traditional Chinese medicine inventions. The Chinese herba preparation for eosinophilic fasciitis comprises the raw materials of gentiana macrophylla, fructus forsythiae, dandelions, herba violae, ligusticum wallichii, peach kernels, safflower carthamus, radix rehmanniae praeparata, radix cyathulae, radix paeoniae alba, angelica sinensis, trogopterus dung, rhizoma cyperi, notopterygium roots, lumbricus, processed leeches, rhizoma curculiginis, herba epimedii, rhizoma anemarrhenae, cortex phellodendri, ephedra herbs, the roots of kudzu vines, semen brassicae and liquoric roots. According to different characteristics of all the traditional Chinese medicine, the traditional Chinese medicine is cleaned, diced and pretreated and then is prepared in proportion, the Chinese herba preparation is manufactured through a special method, and the effects of dispelling wind and clearing away heat, relieving swelling and dehumidifying, activating and nourishing blood and eliminating cold to stop pains are achieved. The combination and the manufacturing method of the Chinese herba preparation are unique. Through clinical verifications, the Chinese herba preparation is obvious in treatment effect, short in treatment period, low in price, free of adverse reactions and any toxic and side effect, and broad in market application prospect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for eosinophilic fasciitis, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Eosinophilic fasciitis (eosinophilicfasciitis) is main with fascia generation anthorisma, the disease being hardened to feature, think that its morbidity is relevant with dysimmunity at present more, as there is hypergammaglobulinemia in some patients, circulating immune complex increases, hypocomplementemia, rheumatoid factor positive, has immunoglobulin deposit or some autoimmune diseasees that simultaneously occur together between fascia.For the ownership of primary disease, have and think that primary disease belongs to a type in scleroderma disease spectrum, namely between local scleroderma and systemic sclerosis, some patient can be converted into systemic sclerosis in the course of disease.
Eosinophilic fasciitis is mainly common with male, and the ratio of men and women is about 2 ︰ 1.Age of onset 30-60 year is many.Premorbid often has overworked history, strenuous exercise, wound, to catch cold and upper respiratory tract infection etc. also may bring out primary disease.Normal with limb skin swelling, tighten, onset of hardening, or have naughty erythema concurrently and joint motion limited.Pathological changes onset position is common with shank bottom with lower limb especially, is secondly forearm, minority from thigh, the onset such as waist and belly or instep.Person accounts for 95% to involve extremity in the course of disease, and hand and foot accounts for 48%, and trunk accounts for 43%, face usually not by and.Characteristic of damage is that subcutaneous deep tissue is firmly swollen, and edge limits to or fills the air unclear.When suffering limb is lifted, disease damage surface irregularity, moves towards visible tunnel, position shape depression along superficial vein.Suffer from district's naughty can pinch, texture is normal, also can accompany pigmentation in various degree.General without obvious General Symptoms, fibroid peripheral neuropathy also can be accompanied to become.
Eosinophilic fasciitis belongs to the category of the traditional Chinese medical science " arthromyodynia ", " BI-syndrome related to skin ", its morbidity when duty in interior be innate deficiency, deficiency of spleen-YANG and kidneyYANG, the outer heresy for cold-damp is invaded by skin, severe injury and check skin and defend outer yang-energy.Extend with PD and the state of an illness, going from the exterior into the interior causes internal organs disorder, and expectorant is turbid to be tied mutually with blood stasis.
At present, oral glucocorticoid has significant curative effect to primary disease, hormone intramuscular injection or local injection, but this kind of adverse effect is more, and comparatively serious, as osteoporosis, severe infections risk, Liver and kidney function damage etc., this makes their clinical practice be subject to certain restrictions.Meanwhile, hormone therapy can only temporary relief of symptoms, and after drug withdrawal, relapse indications increases the weight of.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for eosinophilic fasciitis, it is remarkable that this Chinese medicine preparation has therapeutic effect for treatment eosinophilic fasciitis, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of eosinophilic fasciitis repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
Radix Gentianae Macrophyllae: be the dry root of gentianaceae plant Radix Gentianae Macrophyllae GentianamacrophyllaPall., gentiana straminea maxim GentianastramineaMaxim., gentiana crassicaulis Duthie GentianacrassicaulisDuthieexBurk. or Gentiana dahurica GentianadahuricaFisch..Nature and flavor: pungent, bitter are flat.Return stomach, liver, gallbladder meridian.Cure mainly wind-damp dispelling, clearing away damp-heat, stopping numbness pain, reducing the asthenic fever.For rheumatic arthralgia, apoplexy and hemiplegia, the contracture of muscle arteries and veins, joint is ached, jaundice due to damp-heat, osteopyrexia and fever, and infantile malnutrition generates heat.
Fructus Forsythiae: be Oleaceae plants Fructus Forsythiae Forsythiasuspensa(Thunb.) dry fruit of Vahl.Nature and flavor: bitter, are slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Record in " herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat.
Herba Taraxaci: be feverfew Herba Taraxaci TaraxacummongolicumHand.-Mazz., alkali ground Herba Taraxaci TaraxacumsinicumKitag. or the dry herb belonging to several plants together.Spend spring to autumn when just opening and excavate, removing impurity, cleans, dries.Nature and flavor: bitter, sweet, cold.Return liver, stomach warp.Cure mainly heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Herba Violae: be the dry herb of Violaceae Chinese violet ViolayedoensisMakino.Nature and flavor: bitter, acrid, cold.GUIXIN, Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.
Herba Violae: be the dry herb of Violaceae Chinese violet ViolayedoensisMakino.Nature and flavor: bitter, acrid, cold.GUIXIN, Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.
Rhizoma Chuanxiong: be samphire Rhizoma Chuanxiong LigusticumchuanxiongHort.(or LigusticumwallichiiFranch.) dry rhizome.Nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Record in " Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken Disorder ties stagnated blood, supports fresh blood, puts on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood.
Semen Persicae: be rosaceous plant Fructus Persicae Prunuspersica(L.) Batsch or Prunus davidiana Prunusdavidiana(Carr.) dry mature seed of Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Record in " herbal classic ": main blood stasis, blood closes lump in the abdomen, pathogen, kills small worm." not Lu ": only cough with dyspnea, disappear hardness in the epigastrium, and except soldier hits blood cruelly, broken lump in the abdomen, promotes blood circulation, pain relieving.
Flos Carthami: be the dried floral of feverfew Flos Carthami CarthamustinctoriusL..Nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.
Radix Rehmanniae Preparata: be the Preparation process product of Radix Rehmanniae.Nature and flavor: sweet, tepor.Return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Record in " pearl sac ": enrich blood greatly empty not enough, promoting blood circulation, physical strength profiting.
Radix Cyathulae: be the dry root of Sichuan amaranthaceous plant Radix Achyranthis Bidentatae AchyranthesbidentataBlume..Nature and flavor: bitter, sour are flat.Return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.Record in " Traditional Chinese Medicine in Sichuan will ": expelling wind and removing dampness, stimulate the menstrual flow loose blood.Control cold-damp waist thigh bone pain, flaccidity of the lower limbs clonic spasm of the muscle, women's amenorrhea and lump in the abdomen, gonorrhea, hematuria, impotence, mistake are drowned.
The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Nature and flavor: bitter, sour, are slightly cold.Return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Record in " herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Radix Angelicae Sinensis: be umbelliferae angelica Angelicasinensis(Oliv.) dry root of Diels.Nature and flavor: sweet, acrid, warm.Return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Record in " Japan hanako materia medica ": control a wind cutting, all blood, mend all labor, broken stagnant blood, supports fresh blood and main Disorder addiction.
Oletum Trogopterori: be flying squirrel section animal trogopterus xanthipes TrogopterusXanthipesMilne-Edwards or the dry feces flying murine little flying squirrel PteromysvolansL..Nature and flavor: sweet, temperature.Effect: promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.Record in " Amplification on Materia Medica addendum ": can promoting the circulation of blood hemostasis.Control trusted subordinate's cold air, married woman is pained, pricking caused by the stagnation of QI and blood.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber CyperusrotundusL..Nature and flavor: pungent, micro-hardship, micro-sweet are flat.Return liver, spleen, tri-jiao channel.Effect: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Record in " detailed outline ": loose seasonal epidemic pathogens is trembled with fear epidemic disease, and profit three is burnt, and separate six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, hematochezia, hematuria, married woman's bleeding not during menses, the moon wait uncomfortable, before tire puerperal all kinds of diseases and ailments.
Rhizoma Et Radix Notopterygii: be dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii (back of the body wing celery) NotopterygiumincisumTingexH.T.Chang or Radix et Rhizoma Notopterygii NotopterygiumforbesiiBoiss..Nature and flavor: pungent, bitter, temperature.Return bladder, kidney channel.Function cures mainly: cold expelling, dispels the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.Record in " Japan hanako materia medica ": control a wind cutting and gas, muscles and bones fist contraction, extremity are thin bad, and head revolves the red pain of eyes and fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times aqueous vapor.
Pheretima: be Ju Yin section animal Pheretima aspergillum Pheretimaaspergillum(E.Perrier), popular Pheretimatschiliensis PheretimavulgarisChen, power simulation Pheretimaguillelmi(Michaelsen) or the dry body of the blind Pheretimatschiliensis PheretimapectiniferaMichaelsen of comb.Nature and flavor: salty, cold.Return liver, spleen, urinary bladder channel.Effect: heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Hirudo (processed): be the processed product of the dry body of Hirudinidae animal whitmania WhitmaniapigraWhitman, Hirudo HirudonipponicaWhitman or Folium Salicis Babylonicae Hirudo Whit-maniaacranulataWhitman.Nature and flavor: salty, bitter are flat; Slightly poisonous.Return Liver Channel.Effect: removing blood stasis, removing blood stasis, stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.
Rhizoma Curculiginis: be the dry rhizome of amrallid Rhizoma Curculiginis CurculigoorchioidesGaertn..Nature and flavor: pungent, heat; Poisonous.Return kidney,liver,spleen warp.Effect: kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.For sexual impotence cold sperm, muscles and bones flaccidity is soft, the cold numbness of waist knee joint, yang deficiency cold diarrhea.Record in " Japan hanako materia medica ": control all pathogenic wind, mend five kinds of strain and seven kinds of impairment, the appetizing therapeutic method to keep the adverse QI flowing downwards.
Herba Epimedii: be Berberidaceae plant Herba Epimedii EpimediumbrevicornumMaxim., Epimedium sagittatum Epimediumsagittatum(Sieb.etZucc.) dry aerial parts of Maxim., E. Pubescens EpimediumpubescensMaxim., Epimedium wushanense EpimediumwushanenseT.S.Ying or Herba Epimedii EpimediumkoreanumNakai.Nature and flavor: acrid, sweet, warm.Return liver, kidney channel.Effect: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension." not Lu ": " hard muscles and bones.Disappear scrofula, red carbuncle; Skin ulcer is arranged at bottom, washes, and goes out worm.
The Rhizoma Anemarrhenae: be the dry rhizome of liliaceous plant Rhizoma Anemarrhenae AnemarrhenaasphodeloidesBunge..Nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect; Clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.Record in " not Lu ": cold chronic malaria dysphoria with smothery sensation of curing the wound, the lower pathogen of the side of body, the disease due to obstruction of QI of middle-JIAO is disliked and subcutaneous ulcer in wind antiperspirant.
Cortex Phellodendri: be the dry bark of rutaceae wampee PhellodendronchinenseSchneid. or Cortex Phellodendri PhellodendronamurenseRupr..Nature and flavor: bitter, cold.Return kidney, urinary bladder channel.Effect: heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.Record in " not Lu ": treat frightened gas between skin, red of skin heat, the hot swelling pain of order, aphtha.
Herba Ephedrae: be the dry herb stem of Ephedraceae plant plait Herba Ephedrae EphedrasinicaStapf, epheday intermedia EphedraintermediaSchrenketC.A.Mey. or ephedra equisetina EphedraequisetinaBge..Nature and flavor: pungent, micro-hardship, temperature.Gui Jing: return lung, urinary bladder channel.Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.Record in " Japan hanako materia medica ": logical nine orifices, blood circulation regulating, imperial epidemic pathogenic factors from mountains.
Radix Puerariae: be legume pueraria lobata Puerarialobata(Willd.) dry root of Ohwi or Radix Puerariae rattan PuerariathomsoniiBenth..Nature and flavor: sweet, pungent, cool.Return spleen, stomach warp.Effect: thirsty, quenches one's thirst, measles without adequate eruption, and hematodiarrhoea, has loose bowels; Hypertension neck pain.Record in " herbal classic ": master quenches one's thirst, and body is too warm, vomiting, all numbness, play cloudy gas, separate all poison.
Semen Sinapis Albae: be the seed of crucifer Caulis et Folium Sinapis albee.Nature and flavor: pungent, temperature.Be included into lung, stomach warp.Effect: promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.Record in " not Lu ": diaphoresis, the cold upper gas of main chest and diaphragm expectorant, face mouth Huang is red.Vinegar grinds to apply and penetrates work poison again.
Radix Glycyrrhizae: be the dry root of glycyrrhizic legume GlycyrrhizauralensisFisch., Glycyrrhiza inflata Bat. GlycyrrhizainflataBat. or Glycyrrhiza glabra L. GlycyrrhizaglabraL..Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Record in " illustrated handbook planted by middle traditional Chinese medicines ": control peptic ulcer and jaundice.
Side's solution of the present invention is: Radix Gentianae Macrophyllae expelling wind and clearing away heat, Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Herba Violae heat-clearing and toxic substances removing, removing heat from blood are subsided a swelling, and notopterygium wind dispelling dehumidifies, Pheretima heat clearing away dredging collateral, Rhizoma Anemarrhenae clearing away heat-fire, Cortex Phellodendri heat clearing and damp drying, above eight taste medicines, as monarch drug in side, have the effect of expelling wind and clearing away heat, detumescence dehumidifying.Chinese medicine is thought, primary disease is interior for innate deficiency, deficiency of spleen-YANG and kidneyYANG, and outer heresy for cold-damp is invaded by skin, severely injured with check skin and defend outer yang-energy so that damp and hot fire-toxin accumulates and amasss and life and cause primary disease.So expelling wind and clearing away heat, detumescence dehumidifying be treatment eosinophilic fasciitis basis, above eight taste medicines are monarch drug, first fundamentally expelling wind and clearing away heat, detumescence dehumidifying, make disease obtain basic control.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Semen Persicae blood circulation promoting and blood stasis dispelling, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, beneficial essence fill out marrow, Radix Paeoniae Alba nourishing blood for regulating menstruation, and Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, Oletum Trogopterori promoting blood circulation to remove blood stasis, ministerial drug in the above seven flavor medicine side of being, returns Liver Channel.Effect of auxiliary monarch drug expelling wind and clearing away heat, detumescence dehumidifying on the one hand; There is as ministerial drug effect of blood-activating and qi-promoting, nourishing blood to restore normal menstruation on the other hand.Radix Cyathulae stimulate the menstrual flow profit joint, Rhizoma Cyperi promoting QI circulation for relieving depression, menstruction regulating and pain relieving, Hirudo (processed) eliminating blood stasis and inducing menstruation, Herba Epimedii, Rhizoma Curculiginis the kidney invigorating cold relieving, Herba Ephedrae cold expelling diuretic, Radix Puerariae is quenched one's thirst removing toxic substances, Semen Sinapis Albae warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain, above eight taste medicines, as adjuvant drug, cause the inducement of eosinophilic fasciitis from pathology treatment, the expelling wind and clearing away heat of the monarch and his subjects two medicine, effect of detumescence dehumidifying can be promoted as adjuvant drug, the effect of body blood-activating and qi-promoting, nourishing blood to restore normal menstruation can be promoted by using corrigent the monarch and his subjects two medicine again.There is as adjuvant drug effect of dispersing cold for relieving pain simultaneously.Radix Glycyrrhizae makes medicine as in side, and have the effect of coordinating the actions of various ingredients in a prescription, mediation flavour of a drug, all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of expelling wind and clearing away heat, detumescence dehumidifying, nourishing blood and promoting blood circulation, dispersing cold for relieving pain, effectively can treat eosinophilic fasciitis.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Bupleuri 22-26 part, Radix Scutellariae 16-20 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8-12 part, Fructus Gardeniae 10-14 part, Radix Curcumae 13-17 part, Polyporus 16-20 part, Poria 16-20 part, Rhizoma Alismatis 16-20 part, Rhizoma Smilacis Glabrae 28-32 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Ramulus Cinnamomi 13-17 part, Radix Gentianae 7-11 part, Folium Isatidis 16-20 part, Radix Glycyrrhizae 7-11 part, Radix Isatidis 16-20 part, Rhizoma Corydalis 18-22 part, Olibanum 7-11 part, Myrrha 7-11 part, Rhizoma Curcumae Longae 13-17 part, Flos Chrysanthemi Indici 8-12 part, Radix Et Rhizoma Rhei 8-12 part, Rhizoma Chuanxiong 13-17 part, Rhizoma Cyperi 10-14 part, Herba Scutellariae Barbatae 16-20 part.
Wherein be preferably: Radix Gentianae Macrophyllae 15 parts, Fructus Forsythiae 18 parts, Herba Taraxaci 20 parts, Herba Violae 10 parts, Rhizoma Chuanxiong 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Rehmanniae Preparata 18 parts, Radix Cyathulae 15 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 18 parts, Oletum Trogopterori 12 parts, Rhizoma Cyperi 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Rhizoma Curculiginis 12 parts, Herba Epimedii 15 parts, the Rhizoma Anemarrhenae 12 parts, Cortex Phellodendri 12 parts, 6 parts, Herba Ephedrae, Radix Puerariae 15 parts, Semen Sinapis Albae 9 parts, Radix Glycyrrhizae 6 parts.
A kind of preparation method of the Chinese medicine preparation for eosinophilic fasciitis is as follows:
Step one: by weight of the present invention, get Radix Rehmanniae Preparata, pulverizes, and crosses 200 mesh sieves, for subsequent use;
Step 2: by weight of the present invention, gets Pheretima, Hirudo (processed) medical material is placed in marmite, adds the water of 8 times of volumes, and intense fire infusion is after 20-30 minute, and fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, and infusion merges gained filtrates three times repeatedly, for subsequent use;
Step 3: by weight proportion of the present invention, get Radix Gentianae Macrophyllae, Semen Persicae, Radix Cyathulae, the Radix Paeoniae Alba, Oletum Trogopterori, Rhizoma Et Radix Notopterygii, Rhizoma Curculiginis, Herba Epimedii, the Rhizoma Anemarrhenae, Cortex Phellodendri, Herba Ephedrae, Radix Puerariae medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Fructus Forsythiae, Herba Taraxaci, Herba Violae, Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Cyperi, Radix Glycyrrhizae and respectively with the Semen Sinapis Albae that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use;
Step 4: by step 3 gained filtrate and step one gained powder, stir evenly, then with the mixing of step 2 gained filtrate, stir evenly, both the decoction for the treatment of eosinophilic fasciitis of the present invention.
Using method of the present invention: get decoction, takes in one hour after meal, every day three times.
Medicine of the present invention has the effect of expelling wind and clearing away heat, detumescence dehumidifying, nourishing blood and promoting blood circulation, dispersing cold for relieving pain, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviate the slight illness of patient, according to clinical 240 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 82.5%, two the total effective rate course for the treatment of 95%.
Detailed description of the invention
Embodiment one: Radix Gentianae Macrophyllae 15 parts, Fructus Forsythiae 18 parts, Herba Taraxaci 20 parts, Herba Violae 10 parts, Rhizoma Chuanxiong 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Rehmanniae Preparata 18 parts, Radix Cyathulae 15 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 18 parts, Oletum Trogopterori 12 parts, Rhizoma Cyperi 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Rhizoma Curculiginis 12 parts, Herba Epimedii 15 parts, the Rhizoma Anemarrhenae 12 parts, Cortex Phellodendri 12 parts, 6 parts, Herba Ephedrae, Radix Puerariae 15 parts, Semen Sinapis Albae 9 parts, Radix Glycyrrhizae 6 parts.
Embodiment two: Radix Gentianae Macrophyllae 16 parts, Fructus Forsythiae 17 parts, Herba Taraxaci 21 parts, Herba Violae 10 parts, Rhizoma Chuanxiong 15 parts, 11 parts, Semen Persicae, 8 parts, Flos Carthami, Radix Rehmanniae Preparata 17 parts, Radix Cyathulae 15 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 19 parts, Oletum Trogopterori 12 parts, Rhizoma Cyperi 14 parts, Rhizoma Et Radix Notopterygii 15 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Rhizoma Curculiginis 13 parts, Herba Epimedii 14 parts, the Rhizoma Anemarrhenae 13 parts, Cortex Phellodendri 12 parts, 7 parts, Herba Ephedrae, Radix Puerariae 15 parts, Semen Sinapis Albae 8 parts, Radix Glycyrrhizae 7 parts.
Embodiment three: Radix Gentianae Macrophyllae 14 parts, Fructus Forsythiae 17 parts, Herba Taraxaci 21 parts, Herba Violae 11 parts, Rhizoma Chuanxiong 15 parts, 13 parts, Semen Persicae, 8 parts, Flos Carthami, Radix Rehmanniae Preparata 18 parts, Radix Cyathulae 14 parts, the Radix Paeoniae Alba 14 parts, Radix Angelicae Sinensis 19 parts, Oletum Trogopterori 12 parts, Rhizoma Cyperi 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Rhizoma Curculiginis 13 parts, Herba Epimedii 14 parts, the Rhizoma Anemarrhenae 13 parts, Cortex Phellodendri 13 parts, 7 parts, Herba Ephedrae, Radix Puerariae 14 parts, Semen Sinapis Albae 8 parts, Radix Glycyrrhizae 7 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept patient's totally 240 examples of eosinophilic fasciitis for medical treatment, male 156 example, women 84 example, the ratio of men and women is 1.8 ︰ 1.Max age 56 years old, minimal ages 16 years old, the course of disease several months to several years is not etc.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, Therapeutic Method:
1, according to Medications Example two of the present invention, and decoction prepared by preferred preparation method, get a daily dose, decocting, take at twice.It within 7th, is a course for the treatment of.
2, matched group adopts traditional oral glucocorticoid treatment, within 7 days, is a course for the treatment of.
Three, efficacy assessment standard:
1, cure: the skin lesion that eosinophilic fasciitis causes, skin turgor, tighten, erythema, joint are limited etc., and clinical symptoms disappears completely, every lab testing all shows normally;
2, take a turn for the better: the skin lesion that eosinophilic fasciitis causes, skin turgor, tighten, erythema, joint are limited etc., and clinical symptoms takes a turn for the better to some extent, every lab testing all makes moderate progress;
3, do not heal: cardinal symptom is without improvement.
Four, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness in treatment chronic interstitial nephropathy, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, Lee, man, 45 years old,, there is skin turgor before patient Yu Yue, hardening have erythema concurrently, two severe lower extremity in people from Weifang, Shandong, through examination in hospital, be diagnosed as eosinophilic fasciitis, adopt made preparation in the embodiment of the present invention two, and the preferred preparation method of institute, the transference cures such as patient's readme limitation of activity, continue to take two courses for the treatment of, the phenomenon of skin turgor, erythema thoroughly disappears, hospital checks, and health, than there being very large improvement in the past, is fully recovered.
Case two, Hu, man, 22 years old, patient was once football player, because quantity of motion is violent, health occurs uncomfortable, joint motion critical constraints, and the symptom of hardening appears in skin, through in many ways checking, finally be diagnosed as eosinophilic fasciitis, adopt made preparation in the embodiment of the present invention one, and the preferred preparation method of institute, take two courses for the treatment of, patient feels to be clearly better, and freely, the phenomenon of sclerosis of the skin fades away joint motion, clinical symptoms thoroughly disappears, patient goes to hospital to check, and indices all shows normally, recovery from illness.
Claims (4)
1. the Chinese medicine preparation for eosinophilic fasciitis, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Bupleuri 22-26 part, Radix Scutellariae 16-20 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8-12 part, Fructus Gardeniae 10-14 part, Radix Curcumae 13-17 part, Polyporus 16-20 part, Poria 16-20 part, Rhizoma Alismatis 16-20 part, Rhizoma Smilacis Glabrae 28-32 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Ramulus Cinnamomi 13-17 part, Radix Gentianae 7-11 part, Folium Isatidis 16-20 part, Radix Glycyrrhizae 7-11 part, Radix Isatidis 16-20 part, Rhizoma Corydalis 18-22 part, Olibanum 7-11 part, Myrrha 7-11 part, Rhizoma Curcumae Longae 13-17 part, Flos Chrysanthemi Indici 8-12 part, Radix Et Rhizoma Rhei 8-12 part, Rhizoma Chuanxiong 13-17 part, Rhizoma Cyperi 10-14 part, Herba Scutellariae Barbatae 16-20 part.
2. the Chinese medicine preparation for eosinophilic fasciitis according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Gentianae Macrophyllae 15 parts, Fructus Forsythiae 18 parts, Herba Taraxaci 20 parts, Herba Violae 10 parts, Rhizoma Chuanxiong 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Rehmanniae Preparata 18 parts, Radix Cyathulae 15 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 18 parts, Oletum Trogopterori 12 parts, Rhizoma Cyperi 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Rhizoma Curculiginis 12 parts, Herba Epimedii 15 parts, the Rhizoma Anemarrhenae 12 parts, Cortex Phellodendri 12 parts, 6 parts, Herba Ephedrae, Radix Puerariae 15 parts, Semen Sinapis Albae 9 parts, Radix Glycyrrhizae 6 parts.
3. the Chinese medicine preparation for eosinophilic fasciitis according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.
4. for a preparation method for the Chinese medicine preparation of eosinophilic fasciitis, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, get Radix Rehmanniae Preparata, pulverizes, and crosses 200 mesh sieves, for subsequent use; Step 2: by weight of the present invention, gets Pheretima, Hirudo (processed) medical material is placed in marmite, adds the water of 8 times of volumes, and intense fire infusion is after 20-30 minute, and fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, and infusion merges gained filtrates three times repeatedly, for subsequent use; Step 3: by weight proportion of the present invention, get Radix Gentianae Macrophyllae, Semen Persicae, Radix Cyathulae, the Radix Paeoniae Alba, Oletum Trogopterori, Rhizoma Et Radix Notopterygii, Rhizoma Curculiginis, Herba Epimedii, the Rhizoma Anemarrhenae, Cortex Phellodendri, Herba Ephedrae, Radix Puerariae medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Fructus Forsythiae, Herba Taraxaci, Herba Violae, Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Cyperi, Radix Glycyrrhizae and respectively with the Semen Sinapis Albae that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 4: by step 3 gained filtrate and step one gained powder, stir evenly, then with the mixing of step 2 gained filtrate, stir evenly, both the decoction for the treatment of eosinophilic fasciitis of the present invention.
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| CN104906497A (en) * | 2015-06-15 | 2015-09-16 | 于霞 | Traditional Chinese medicine preparation for treating eosinophilic fasciitis and preparation method of traditional Chinese medicine preparation |
| CN104922595A (en) * | 2015-07-02 | 2015-09-23 | 张晓风 | Traditional Chinese medicinal preparation for herpes zoster and preparation method thereof |
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| CN104922595A (en) * | 2015-07-02 | 2015-09-23 | 张晓风 | Traditional Chinese medicinal preparation for herpes zoster and preparation method thereof |
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Application publication date: 20151230 |