CN104983697A - Chewable tablets made of coenzyme Q10 - Google Patents

Chewable tablets made of coenzyme Q10 Download PDF

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Publication number
CN104983697A
CN104983697A CN201510353720.0A CN201510353720A CN104983697A CN 104983697 A CN104983697 A CN 104983697A CN 201510353720 A CN201510353720 A CN 201510353720A CN 104983697 A CN104983697 A CN 104983697A
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CN
China
Prior art keywords
coenzyme
tablets
lactose
chewable tablet
magnesium stearate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510353720.0A
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Chinese (zh)
Inventor
邢文华
王秋岭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Sheng Hai Health Product Co Ltd
Original Assignee
Shandong Sheng Hai Health Product Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong Sheng Hai Health Product Co Ltd filed Critical Shandong Sheng Hai Health Product Co Ltd
Priority to CN201510353720.0A priority Critical patent/CN104983697A/en
Publication of CN104983697A publication Critical patent/CN104983697A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to chewable tablets made of coenzyme Q10. Contents of the tablets are made of, by weight, 3.000-7.000% of the coenzyme Q10, 50.000-70.000% of lactose, 15.000-30.000% of microcrystalline cellulose, 2.000-1.000% of silica, 0.100-0.900% of magnesium stearate and 0.100-0.90% of fragrant citrus essence. According to the chewable tablet made of the coenzyme Q10, the mixing ratio is scientific, no toxic or side effect exists, the immune system is strengthened, the heart, liver and renal functions are protected, and harm of free radicals is avoided; the technical content is high, and if the tablets are eaten frequently, the body-building can be achieved. For an adult who is unsound in immunity, nutrition can be better supplemented, and the tablets are convenient to carry and eat.

Description

Coenzyme Q10 chewable tablet
Technical field
The present invention relates to a kind of coenzyme Q10 chewable tablet.
Background technology
Coenzyme Q10 is a kind of chemical composition be extensively present in biological cell, has no side effect.It is the basis that human body cell energy manufactures, and has metabolic cardiotonic, definite effect.Coenzyme Q10 is mainly used in the treatment of acute and chronic viral hepatitis, acute severe hepatitis, has extraordinary curative effect to cardiovascular disease and hypertension, and it can also be used for the Comprehensive Treatment of cancer, simultaneously unique effect in defying age, resisting fatigue, fat-reducing and beauty treatment etc.Be yellow to orange-yellow crystalline powder under coenzyme Q10 room temperature, fusing point lower (49-52 DEG C), odorless, tasteless, dissolve in chloroform, benzene, acetone, ether or petroleum ether, slightly dissolve in ethanol, insoluble in water and formaldehyde, be not easy to absorb in human body, bioavailability is poor; Coenzyme Q10 is to light sensitive, and meet photolysis and become red material, temperature and humidity is relatively little.
In order to play the health-care effect of coenzyme Q10 to greatest extent, need the technique of science and the formula of science by the efficacy exertion of coenzyme Q10 out, waste could to be avoided, also avoid having side effects.
Summary of the invention
The object of this invention is to provide a kind of coenzyme Q10 chewable tablet, proportioning science, has no side effect, and strengthens immune system, and the protection heart, Liver and kidney function, from free radical damage; With high content of technology, regular edible, can building body.For the unsound adult of immunity, better can supplement the nutrients, be convenient for carrying and eat.
A kind of coenzyme Q10 chewable tablet of the present invention, described content is made up of the raw material of following weight percentage:
Coenzyme Q10: 3.000-7.000%, lactose: 50.000-70.000%, microcrystalline Cellulose: 15.000-30.000%, silicon dioxide: 2.000-1.000%, magnesium stearate: 0.100-0.900%, fragrant citrus essence: 0.100-0.90%.
Described content is made up of the raw material of following weight percentage: coenzyme Q10: 7.000%, lactose: 70.000%, microcrystalline Cellulose: 20.830%, silicon dioxide: 1.160%, magnesium stearate: 0.500%, fragrant citrus essence: 0.500%.
The present invention's raw material used is commercially available.
Formula of the present invention is more conducive to significantly improving the bioavailability of coenzyme Q10 in human body.
Adopt the method for microbial cell fermentation, use red pole hair bacillus as fermented bacterium, the enzyme cultivated out is easily controlled, obtain higher, the easy purification of enzyme rate, bioavailability is high, effective, is real health preserving treasure.
Adopt the critical abstraction technique of carbon dioxide ultralow temperature to purify, coenzyme Q10 high purity 99.9%, activity are high, easily absorb, and energy is scavenger cell rubbish fast, recovers healthy.
Even if the long-time n of high dose oral coenzyme Q10 of the present invention, human body also can tolerate very well.
Compared with prior art, the present invention has following beneficial effect:
Proportioning science of the present invention, has no side effect, and starts and transport energy in cell, strengthens immune system, and the protection heart, Liver and kidney function, from free radical damage; With high content of technology, regular edible, can building body.For the unsound adult of immunity, better can supplement the nutrients, be convenient for carrying and eat.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, but it is not limited to the following example.
Embodiment 1
A kind of coenzyme Q10 chewable tablet described in the present embodiment, described content is made up of the raw material of following weight percentage,
Coenzyme Q10: 7.000%, lactose: 70.000%, microcrystalline Cellulose: 20.830%, silicon dioxide: 1.170%, magnesium stearate: 0.500%, fragrant citrus essence: 0.500%.
The preparation method of coenzyme Q10 chewable tablet, preparation process is as follows:
(1) pulverize, sieve, weigh
Cross 100 mesh sieves after being pulverized by white sugar, weigh for subsequent use; All the other supplementary materials all cross 100 mesh sieves, weigh for subsequent use.
(2) mix
By various raw material by mixing.
(3) tabletting
Above-mentioned total mixed granule is placed in tablet machine tabletting, and the heavy 0.7g/ sheet of sheet, strictly controls tablet weight variation;
Embodiment 2
A kind of coenzyme Q10 chewable tablet described in the present embodiment, described content is made up of the raw material of following weight percentage:
Coenzyme Q10: 10.000%, lactose: 66.000%, microcrystalline Cellulose: 21.4%, silicon dioxide: 1.5%, magnesium stearate: 0.600%, fragrant citrus essence: 0.500%.
(4) the present embodiment is identical with the preparation method of embodiment 1.Difference is, crosses 80 mesh sieves, weigh for subsequent use after being pulverized by white sugar; All the other supplementary materials all cross 80 mesh sieves, weigh for subsequent use.
Embodiment 3
A kind of coenzyme Q10 chewable tablet described in the present embodiment, is characterized in that: described content is made up of the raw material of following weight percentage:
Coenzyme Q10: 9.050%, lactose: 68.30%, microcrystalline Cellulose: 20.03%, silicon dioxide: 1.32%, magnesium stearate: 0.700%, fragrant citrus essence: 0.600%.
(5) the present embodiment is identical with the preparation method of embodiment 1.Difference is, crosses 90 mesh sieves, weigh for subsequent use after being pulverized by white sugar; All the other supplementary materials all cross 90 mesh sieves, weigh for subsequent use.

Claims (2)

1. a coenzyme Q10 chewable tablet, is characterized in that: described content is made up of the raw material of following weight percentage:
Coenzyme Q10: 3.000-7.000%, lactose: 50.000-70.000%, microcrystalline Cellulose: 15.000-30.000%, silicon dioxide: 2.000-1.000%, magnesium stearate: 0.100-0.900%, fragrant citrus essence: 0.100-0.90%.
2. coenzyme Q10 chewable tablet according to claim 1, it is characterized in that: described content is made up of the raw material of following weight percentage: coenzyme Q10: 7.000%, lactose: 70.000%, microcrystalline Cellulose: 20.830%, silicon dioxide: 1.160%, magnesium stearate: 0.500%, fragrant citrus essence: 0.500%.
CN201510353720.0A 2015-06-24 2015-06-24 Chewable tablets made of coenzyme Q10 Pending CN104983697A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510353720.0A CN104983697A (en) 2015-06-24 2015-06-24 Chewable tablets made of coenzyme Q10

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510353720.0A CN104983697A (en) 2015-06-24 2015-06-24 Chewable tablets made of coenzyme Q10

Publications (1)

Publication Number Publication Date
CN104983697A true CN104983697A (en) 2015-10-21

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CN (1) CN104983697A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107281156A (en) * 2017-07-25 2017-10-24 郑州博凯医药保健品有限公司 Contain ubiquinone10With the effervescent tablet of anthocyanidin and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1961869A (en) * 2006-11-30 2007-05-16 重庆市力扬医药开发有限公司 Orally disintegrating tablet of coenzyme Q10 and preparation method thereof
CN101019849A (en) * 2006-02-16 2007-08-22 北京奇源益德药物研究所 Compound coenzyme Q10 medicine prepn and its prepn process and application
US20090060993A1 (en) * 2007-09-04 2009-03-05 Joseph Schwarz Solid pharmaceutical composition for enhanced delivery of coenzyme q-10 and ubiquinones
US20090246186A1 (en) * 2006-03-29 2009-10-01 Kaneka Corporation Agent for improving nervous system cell functions
CN101801364A (en) * 2007-07-11 2010-08-11 (株)中外制药 Multi-layered vitamin complex tablet containing ubidecarenone

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101019849A (en) * 2006-02-16 2007-08-22 北京奇源益德药物研究所 Compound coenzyme Q10 medicine prepn and its prepn process and application
US20090246186A1 (en) * 2006-03-29 2009-10-01 Kaneka Corporation Agent for improving nervous system cell functions
CN1961869A (en) * 2006-11-30 2007-05-16 重庆市力扬医药开发有限公司 Orally disintegrating tablet of coenzyme Q10 and preparation method thereof
CN101801364A (en) * 2007-07-11 2010-08-11 (株)中外制药 Multi-layered vitamin complex tablet containing ubidecarenone
US20090060993A1 (en) * 2007-09-04 2009-03-05 Joseph Schwarz Solid pharmaceutical composition for enhanced delivery of coenzyme q-10 and ubiquinones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107281156A (en) * 2017-07-25 2017-10-24 郑州博凯医药保健品有限公司 Contain ubiquinone10With the effervescent tablet of anthocyanidin and preparation method thereof

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Application publication date: 20151021