CN104971268A - Nursing medicine for treating chronic eczema scroti and preparation method thereof - Google Patents
Nursing medicine for treating chronic eczema scroti and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of medicines and in particular relates to a nursing medicine for treating chronic eczema scroti and a preparation method thereof. The nursing medicine for treating the chronic eczema scroti is prepared from the following components: coix seed, poria cocos, ligusticum wallichii, divaricate saposhnikovia root, cortex dictamni, fructus kochiae, cicada slough, arillus longan, black soyabean coat, folium mori and alum. The nursing medicine for treating the chronic eczema scroti is taken orally and externally applied, has obvious curative effects of strengthening spleen and dehumidifying, nourishing blood and moistening skin as well as dispelling wind and relieving itching and can be taken as an effective medicine used for nursing and treating chronic eczema scroti, especially chronic blood deficiency wind-dryness type eczema scroti.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of nursing medicine for the treatment of chronic eczema of scrotum and preparation method thereof.
Background technology
Eczema scrotum is a kind of anaphylaxis dermatosis common in eczema, is confined to skin of scrotum, has time delay and perianal, mainly contains the types such as acute, subacute and chronic clinically.The main subjective symptoms of acute eczema scrotum is pruritus, the pruritus of patient Chang Yin scrotum and find primary disease.Subacute is changed by acute eczema scrotum, and show as skin of scrotum slightly thickening and slight erosion, squama is more, and sepage is very few, still has violent pruritus.Chronic eczema of scrotum be by acute, subacute eczema is not healed for a long time, recurrent exerbation.Because the time is long, add and constantly scratch, make the xerosis cutis of scrotum plump, wrinkle deepens, and in Cortex walnut shape, often has very thin crust and squama, and skin pigment is deepened; Also have the situation causing hypopigmentation because scratching, usually violent pruritus, cannot fall asleep.Society is due to the change of climatic environment, dietary structure, the quickening of rhythm of life, the increase of stress, the application etc. of a large amount of chemicals, the sickness rate of eczema scrotum is in rising trend, because eczema scrotum sufferer position is special, how with violent pruritus, and course of disease delay easily repeatedly, bring very big puzzlement to the life of patient, work.
Clinical treatment chronic eczema of scrotum method is varied, current doctor trained in Western medicine often gives antihistaminic, vitamin C, sedative hypnotic medicine, coordinate external used medicine as the Drug therapy such as cortical steroid, immunosuppressant, curative effect still can, but there is relevant side effect or potential risk more.In recent years, modern doctor uses the core concept of differentiation of tcm achieve good curative effect to treat various eczema and have accumulated rich experience, relative to western medical treatment, more effectively can reduce relapse rate by Chinese traditional treatment means, promote human righteousness, opposing exopathogen.Therefore Chinese medicine eczema has powerful advantages, is worth further genralrlization application in clinical practice.
Summary of the invention
The invention provides a kind of nursing medicine for the treatment of chronic eczema of scrotum, its safety is high, effective, can be used as the ideal medicament of nursing chronic eczema of scrotum.Medicament composing prescription of the present invention is rigorous, compatibility science, easy to prepare, and patient compliance is good, has no side effect, clinic promotion and application.
For achieving the above object, technical scheme provided by the invention is the nursing medicine of described treatment chronic eczema of scrotum, and it by the composition and ratio of crude drug is: Semen Coicis 13-15g, Poria 7-10g, Rhizoma Chuanxiong 8-11g, Radix Saposhnikoviae 6-8g, Cortex Dictamni 10-12g, Fructus Kochiae 8-10g, Periostracum Cicadae 8-10g, Arillus Longan 10-12g, SEMEN COAT GLYCINES NIGRUM 7-9g, Folium Mori 10-14g, Alumen 10-14g.
Optimal technical scheme of the present invention is, nursing medicine of the present invention is obtained by the material medicine of following weight proportion: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g, Alumen 12g.
Described a kind of nursing medicine for the treatment of chronic eczema of scrotum can be made into oral formulations or external preparation.Described oral formulations is preferably tablet, capsule or granule, more preferably capsule.Described external preparation is preferably lotion, liniment or ointment, is more preferably prepared into ointment.
Present invention also offers the preparation method of described nursing medicine, the preparation method of wherein said oral formulations comprises following steps: take above Chinese medicine each component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, adds pharmaceutically acceptable excipients make clinical acceptable dosage form through normal process steps.
The preparation method of described external preparation comprises following steps: take above Chinese medicine each component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, adds the Alumen of recipe quantity, is ground into fine powder, add pharmaceutically acceptable excipients make clinical acceptable dosage form through normal process steps.
The present invention also asks the purposes protecting above-mentioned nursing medicine in the care drug of preparation treatment chronic eczema of scrotum.The purposes of particularly described nursing pharmaceutical preparation in the medicine of preparation treatment blood-deficiency and wind-dry type chronic eczema of scrotum.
The invention provides the clinical observation of described nursing medicine at treatment chronic eczema of scrotum:
1, diagnostic criteria: chronic eczema of scrotum diagnostic criteria that all cases all meets " clinic skin venerology ".Tcm diagnosis meets blood-deficiency and wind-dry type, and disease is seen: skin lesion is dry, coarse, plump, lichenification, visible scratch, desquamation, companion's pruritus, and the course of disease is delayed; Light red tongue, beats with a stick white, thready pulse.
2, physical data: select hospital outpatient and ward blood-deficiency and wind-dry type chronic eczema of scrotum patient 80 example, age 18-70 year, average 39.4 ± 4.2 years old; The course of disease 6 months-15 years.All patients do not take steroid medicine and antihistamine drug in the recent period, do not carry out special treatment.80 routine patients are divided into treatment group and matched group at random, often organize 40 examples, and two groups of cases do not have statistical significance (P > 0.05) in the difference of age, course of disease time and coincident with severity degree of condition.
3, exclusion standard: merge intentionally, cerebrovascular, liver, severe primary disease, the psychotic such as kidney and hemopoietic system; Do not meet inclusive criteria, not by regulation medication, cannot curative effect person be judged.
4, Therapeutic Method:
Matched group: morning oral cetirizine sheet 10mg; Evening, per os hora somni Cyproheptadine sheet 4mg, put Yi Feisha ointment on the skin 2-3 time outside every day simultaneously.
Treatment group: take capsule prepared by embodiment 1, half an hour is oral after meal, one day twice, each 2-4 grain, every, containing crude drug amount 0.15g, uses the ointment prepared by embodiment 7 simultaneously, applies affected part gently, every day 2-3 time at every turn.
The course for the treatment of: treating two weeks is a course for the treatment of, treatment adds up clinical efficacy after two courses for the treatment of continuously.Patient's diet tobacco and wine, urine smell, pungent, stimulating food during nursing for treating, as fish and shrimp, Carnis Canitis, Carnis caprae seu ovis, Sanguis sus domestica, Folium Allii tuberosi, Herba Alii fistulosi, Bulbus Allii, Fructus Capsici etc.; Trousers should be loose, and underwear duty is changed clothes, and keeps dry and comfortable; Scrotum should not wash with water, more should not wash with soap, and also should not put on the skin with outside tiger balm, Herba Menthae wet goods, pruritus should not be scratched.
5, the standard of curative effect evaluation:
1. cure: scrotum skin lesion all disappears and takes off, without plumpness, sepage, incrustation;
2. effective: skin lesion disappears 70%, without pruritus, sepage;
3. effective: skin lesion disappears and takes off 30%, there is slight pruritus;
4. invalid: skin lesion and subjective symptoms are without alleviating.
Total effective rate=cure rate+obvious effective rate.
6, therapeutic effect:
80 routine patients, without coming off, exiting case, all complete clinical observation.
2 courses for the treatment of terminate the rear therapeutic effect to two groups of patients and carry out observation and comparison, the routine patient of matched group 40, and 7 examples are cured, and 18 examples are effective, and 11 examples effectively, 4 examples are invalid, total effective rate 62.5%, the routine patient for the treatment of group 40, and 15 examples are cured, 21 examples are effective, and effectively, 1 example is invalid, total effective rate 90% for 3 examples.Treatment group is obviously better than matched group.Concrete clinical efficacy the results are shown in following table 1.
Table 1. liang group Clinical efficacy comparison
Group | n | Cure | Effective | Effectively | Invalid | Total effective rate |
Matched group | 40 | 7 | 18 | 11 | 4 | 62.5% |
Treatment group | 40 | 15 | 21 | 3 | 1 | 90% |
The above results shows, after chronic eczema of scrotum patient the application of the invention nursing Drug therapy, symptom can significantly improve, and in addition, treatment group before the treatment rear body weight, heart rate, blood pressure is showed no obvious change.Treatment group does not find obvious adverse events in whole therapeutic process.Illustrate that nursing medicine of the present invention is at treatment chronic eczema of scrotum particularly determined curative effect in treatment blood-deficiency and wind-dry type chronic eczema of scrotum thus, safety is high, can be used as the nursing medicine of chronic eczema of scrotum first-selection, is worth studying and applying further.
The present invention, relative to prior art, has following clear superiority:
Its etiology and pathogenesis system eating and drinking without temperance of chronic eczema of scrotum or cross ichthyophagy raw meat, the pungent product starting wind, injures taste, dysfunction of the spleen in transportation, so that damp and hot interior life, doublely experiences external wind, wet, hot heresy, and interior exopathogen is fought mutually, fills in space between skin and muscles, contamination skin; If the course of disease is delayed, consumption impairment of YIN blood, the raw wind of dryness-transformation.Nursing medicament composing prescription of the present invention develops according to the pathogenic characteristic of chronic eczema of scrotum patient, follows traditional Chinese medical science compatibility theory, Semen Coicis in side, Poria spleen invigorating eliminating dampness by diuresis, promoting diuresis to calm the heart; Rhizoma Chuanxiong, Radix Saposhnikoviae, Cortex Dictamni, heat clearing and damp drying, removing toxic substances are dispeled the wind; The Fructus Kochiae, Periostracum Cicadae, dispelling wind for relieving itching, clearing heat for promoting eruption; Arillus Longan, SEMEN COAT GLYCINES NIGRUM, spleen reinforcing is nourished blood, and calms the nerves and dispels the wind; Folium Mori, dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness; Alumen, the outer used time adds, and has removing toxic substances parasite killing, the merit of dampness removing to stop itchin.In prescription, all medicines share and have the antipruritic significant curative effect of spleen invigorating dehumidifying, blood-nourishing skin-moisturizing, dispelling wind, have extremely strong pertinent nursing effect to chronic eczema of scrotum especially blood-deficiency and wind-dry type chronic eczema of scrotum.Through clinical practice checking, its determined curative effect, mild in medicine property and, easy to use, do not occur toxic and side effects and untoward reaction, safety coefficient is high.
Further, in nursing medicine of the present invention, the function of each crude drug cures mainly:
Semen Coicis is sweet, light, cool.Return spleen, stomach, lung meridian.Spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Poria is sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Chuanxiong, pungent, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Saposhnikoviae, acrid, sweet, warm.Return bladder, liver, spleen channel.Inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Cortex Dictamni is bitter, cold.Return spleen, stomach, urinary bladder channel.Heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.
The Fructus Kochiae is pungent, bitter, cold.Return kidney, urinary bladder channel.Clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Periostracum Cicadae, sweet, cold.Return lung, Liver Channel.Loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Arillus Longan, sweet, temperature.GUIXIN, spleen channel.Invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
SEMEN COAT GLYCINES NIGRUM, nourishing blood to expel wind.Cure mainly night sweat due to yin deficiency, deficiency-heat, agitation, dizzy blurred vision, cold in blood, migratory arthralgia.
Folium Mori are sweet, bitter, cold.Return lung, Liver Channel.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.
Alumen is sour, puckery, cold.Return lung, spleen, liver, large intestine channel.External removing toxic substances parasite killing, dampness removing to stop itchin; Hemostasis antidiarrheal for oral administration, dispels wind-phlegm.External treatment is used for eczema, scabies, Ting discharging ear; Take orally for incessant chronic diarrhea, have blood in stool, metrorrhagia, epilepsy is gone mad.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following specific embodiment.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
Embodiment 1 capsule
The each raw material of the present invention is taken: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, pulverize into fine powder, crosses 150 mesh sieves; Make wetting agent with 50% ethanol, be uniformly mixed agent and become soft material, 30 mesh sieves are granulated; Drying, granulate, mix homogeneously incapsulates and obtains capsule of the present invention.
When using the present invention to nurse with Drug therapy chronic eczema of scrotum, take prepared capsule, every contains crude drug amount 0.15g, and every day 2 times, each 2-4 grain, takes after meal half an hour.
Embodiment 2 capsule
The each raw material of the present invention is taken: Semen Coicis 13g, Poria 7g, Rhizoma Chuanxiong 8g, Radix Saposhnikoviae 6g, Cortex Dictamni 10g, Fructus Kochiae 8g, Periostracum Cicadae 8g, Arillus Longan 10g, SEMEN COAT GLYCINES NIGRUM 7g, Folium Mori 10g by following weight proportion.
Preparation technology is with embodiment 1.
Embodiment 3 capsule
The each raw material of the present invention is taken: Semen Coicis 15g, Poria 10g, Rhizoma Chuanxiong 11g, Radix Saposhnikoviae 8g, Cortex Dictamni 12g, Fructus Kochiae 10g, Periostracum Cicadae 10g, Arillus Longan 12g, SEMEN COAT GLYCINES NIGRUM 9g, Folium Mori 14g by following weight proportion.
Preparation technology is with embodiment 1.
Embodiment 4 tablet
The each raw material of the present invention is taken: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, pulverize into fine powder, crosses 150 mesh sieves; Add the magnesium stearate of 1%, mix to obtain slow release layer granule, tabletting, Hardness Control is at 5.7kg/mm
2, namely coating obtains Tablets.
When using Chinese medicine preparation of the present invention to treat chronic eczema of scrotum, take prepared tablet, every sheet is containing crude drug amount 0.15g, and each 2-4 sheet, every day 2 times, takes after meal half an hour.
Embodiment 5 granule
The each raw material of the present invention is taken: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, pulverize into fine powder, crosses 150 mesh sieves; Add the adjuvant soft materials such as appropriate mannitol, make wet granular and cross 40 mesh sieves, dry, granulate, sieves again, and granule of the present invention is packed and obtained in pack.
When using Chinese medicine preparation of the present invention to treat chronic eczema of scrotum, take prepared granule, containing crude drug amount 0.5g, every day 2 times, each 1 bag, take half an hour after meal for every bag.
Embodiment 6 liniment
The each raw material of the present invention is taken: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g, Alumen 12g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, adds the Alumen of recipe quantity, is ground into fine powder, crosses 150 mesh sieves, and add Oleum Sesami appropriate, the dry wetting phase degree of being preferably of tune, makes liniment through normal process steps.
When using the present invention to nurse with Drug therapy chronic eczema of scrotum, every 15g liniment, containing crude drug amount 5g, uses prepared liniment, applies affected part gently at every turn, every day 2-3 time.
Embodiment 7 ointment
The each raw material of the present invention is taken: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g, Alumen 12g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, adds the Alumen of recipe quantity, is ground into fine powder, crosses 150 mesh sieves, adds pharmaceutically acceptable excipients make ointment through normal process steps.
When using the present invention to nurse with Drug therapy chronic eczema of scrotum, every 15g ointment, containing crude drug amount 5g, uses prepared ointment, applies affected part gently at every turn, every day 2-3 time.
Embodiment 8 ointment
The each raw material of the present invention is taken: Semen Coicis 13g, Poria 7g, Rhizoma Chuanxiong 8g, Radix Saposhnikoviae 6g, Cortex Dictamni 10g, Fructus Kochiae 8g, Periostracum Cicadae 8g, Arillus Longan 10g, SEMEN COAT GLYCINES NIGRUM 7g, Folium Mori 10g, Alumen 10g by following weight proportion.
Preparation technology is with embodiment 7.
Embodiment 9 ointment
The each raw material of the present invention is taken: Semen Coicis 15g, Poria 10g, Rhizoma Chuanxiong 11g, Radix Saposhnikoviae 8g, Cortex Dictamni 12g, Fructus Kochiae 10g, Periostracum Cicadae 10g, Arillus Longan 12g, SEMEN COAT GLYCINES NIGRUM 9g, Folium Mori 14g, Alumen 14g by following weight proportion.
Preparation technology is with embodiment 7.
Claims (9)
1. treat a nursing medicine for chronic eczema of scrotum, it is characterized in that, the composition and ratio of its crude drug is: Semen Coicis 13-15g, Poria 7-10g, Rhizoma Chuanxiong 8-11g, Radix Saposhnikoviae 6-8g, Cortex Dictamni 10-12g, Fructus Kochiae 8-10g, Periostracum Cicadae 8-10g, Arillus Longan 10-12g, SEMEN COAT GLYCINES NIGRUM 7-9g, Folium Mori 10-14g, Alumen 10-14g.
2. a kind of nursing medicine for the treatment of chronic eczema of scrotum as claimed in claim 1, it is characterized in that, the composition and ratio of its primary raw material medicine is: Semen Coicis 14g, Poria 8g, Rhizoma Chuanxiong 9g, Radix Saposhnikoviae 7g, Cortex Dictamni 11g, Fructus Kochiae 9g, Periostracum Cicadae 9g, Arillus Longan 11g, SEMEN COAT GLYCINES NIGRUM 8g, Folium Mori 12g, Alumen 12g.
3., as claim 1, the nursing medicine of any one the treatment chronic eczema of scrotum described in 2, it is characterized in that, described nursing medicine can be made into oral formulations or external preparation.
4. a kind of nursing medicine for the treatment of chronic eczema of scrotum as claimed in claim 3, it is characterized in that, described oral formulations is preferably tablet, capsule or granule.
5. a kind of nursing medicine for the treatment of chronic eczema of scrotum as claimed in claim 3, it is characterized in that, described external preparation is preferably lotion, liniment or ointment.
6. the preparation method of oral formulations comprises following steps as claimed in claim 4: take above Chinese medicine each component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, adds pharmaceutically acceptable excipients make clinical acceptable dosage form through normal process steps.
7. the preparation method of external preparation comprises following steps as claimed in claim 5: take above Chinese medicine each component except Alumen according to aforesaid weight and pulverized 120 mesh sieves respectively, decoct 2 times after soaking 2-3h, add medicine gross weight 6-8 water doubly at every turn, decoct 2-3h, merge decoction liquor, filter; When filtrate concentrates 75 DEG C, relative density is the extractum of 1.11-1.21, dry, adds the Alumen of recipe quantity, is ground into fine powder, add pharmaceutically acceptable excipients make clinical acceptable dosage form through normal process steps.
8. the purposes of nursing medicine as claimed in claim 1 or 2 in the medicine of preparation treatment chronic eczema of scrotum.
9. the purposes of nursing medicine as claimed in claim 1 or 2 in the medicine of preparation treatment blood-deficiency and wind-dry type chronic eczema of scrotum.
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JP2019127439A (en) * | 2018-01-22 | 2019-08-01 | 株式会社お茶村 | Supplement comprising morus alba leaves |
CN113456784A (en) * | 2021-08-20 | 2021-10-01 | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | Traditional Chinese medicine composition for treating chronic recurrent eczema |
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CN113456784A (en) * | 2021-08-20 | 2021-10-01 | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | Traditional Chinese medicine composition for treating chronic recurrent eczema |
CN113456784B (en) * | 2021-08-20 | 2022-06-10 | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | Traditional Chinese medicine composition for treating chronic recurrent eczema |
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