CN104587304B - A kind of medicine for the treatment of Simple Obesity and uses thereof - Google Patents
A kind of medicine for the treatment of Simple Obesity and uses thereof Download PDFInfo
- Publication number
- CN104587304B CN104587304B CN201510090037.2A CN201510090037A CN104587304B CN 104587304 B CN104587304 B CN 104587304B CN 201510090037 A CN201510090037 A CN 201510090037A CN 104587304 B CN104587304 B CN 104587304B
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine
- simple obesity
- fructus aurantii
- semen coicis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 46
- 208000008589 Obesity Diseases 0.000 title claims abstract description 34
- 235000020824 obesity Nutrition 0.000 title claims abstract description 33
- 239000010135 fructus aurantii immaturus Substances 0.000 claims abstract description 20
- 210000000582 semen Anatomy 0.000 claims abstract description 20
- 206010003549 asthenia Diseases 0.000 claims abstract description 7
- 230000003393 splenic effect Effects 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims description 18
- 239000000843 powder Substances 0.000 claims description 15
- 229940079593 drug Drugs 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000002775 capsule Substances 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 4
- 239000003826 tablet Substances 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000002994 raw material Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 230000001225 therapeutic effect Effects 0.000 abstract description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 11
- 208000026435 phlegm Diseases 0.000 description 11
- 210000000952 spleen Anatomy 0.000 description 10
- 206010030113 Oedema Diseases 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 208000004611 Abdominal Obesity Diseases 0.000 description 4
- 206010065941 Central obesity Diseases 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 4
- 206010033307 Overweight Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 239000002934 diuretic Substances 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 206010018498 Goitre Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 206010062575 Muscle contracture Diseases 0.000 description 2
- 206010030302 Oliguria Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 208000006111 contracture Diseases 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 206010013990 dysuria Diseases 0.000 description 2
- 201000003872 goiter Diseases 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000001047 pyretic effect Effects 0.000 description 2
- 230000002787 reinforcement Effects 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 210000000115 thoracic cavity Anatomy 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- 208000018779 Globus Sensation Diseases 0.000 description 1
- 208000002705 Glucose Intolerance Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 241001601725 Sthenias Species 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 241000934136 Verruca Species 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000002547 anomalous effect Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 208000012839 conversion disease Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 201000009104 prediabetes syndrome Diseases 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- -1 sublimed preparation Substances 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to medical art, relate to a kind of medicine for the treatment of Simple Obesity and uses thereof.Described medicine is obtained by following raw material: Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae.The therapeutic effect of medicine of the present invention to Simple Obesity particularly Splenic asthenia and obstruction of dampness Simple Obesity is given prominence to, and obviously can improve patients ' life quality, and without obvious toxic-side effects.
Description
Technical field
The invention belongs to medical art, relate to a kind of medicine for the treatment of Simple Obesity and uses thereof.
Background technology
In recent years, along with people's dietary structure and living-pattern preservation, obesity prevalence rises gradually.At present, obesity, as a kind of disease common clinically, divides Simple Obesity and Secondary Obesity.Wherein Simple Obesity is that body fat overheap causes.Simple Obesity is a lot of after the middle age, and centering senior health and fitness brings high risks.
Modern medicine thinks fat and insulin resistant in body, Anomalous lipid metablism are relevant, and obese patient often has the phenomenons such as impaired glucose tolerance, blood fat height.Motherland's medical science is thought causes the many deficiency of the spleen and heat of the stomach of obese patient, stagnation of phlegm-damp in middle-JIAO or stagnation of QI due to depression of the liver phlegm-damp to stay between the visceral muscles natural fibre line of meat, becomes stasis burden, and life is quenched one's thirst in of a specified duration even can becoming, all diseases of apoplexy, the thoracic obstruction, and treatment should be early.
China's Chinese medicine aboundresources, cheap, dialectical, differential diagnosis of diseases, correctly, reasonably uses Chinese medicine, can improve clinical efficacy to a certain extent, have the advantage that doctor trained in Western medicine is incomparable.The pathology mainly deficiency in origin and excess in superficiality of Simple Obesity, therefore the Therapeutic Principle of primary disease works as in accordance with treatment of deficiency-syndrome by reinforcement, sthenia syndrome requiring purgation.Reinforcement is the kidney invigorating mainly, spleen invigorating, QI invigorating; Catharsis mainly contains removing dampness, diuretic, and heat clearing away is eliminated the phlegm, blood stasis dispelling, the turbid descending etc.According to different body constitution, different clinical manifestation, determine pattern of syndrome and square medicine, therapeutic effect is remarkable, is conducive to clinical application.
Summary of the invention
The invention provides a kind of medicine for the treatment of Simple Obesity, this medicament composing prescription is simple, and good effect, side effect is little, and it is obtained by following crude drug: Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae.
Described Caulis Trachelospermi, bitter, be slightly cold.GUIXIN, liver, kidney channel.Dispelling wind and removing obstruction in the collateral, removing heat from blood is subsided a swelling.For beriberoid pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down.
Spica Prunellae is pungent, bitter, cold.Return liver, gallbladder meridian.Relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Semen Coicis is sweet, light, cool.Return spleen, stomach, lung meridian.Spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Folium Sennae, sweet, bitter, cold.Return large intestine channel.The row that purges heat is stagnant, relieving constipation, diuretic.Stagnate for accumulation of heat, constipation is suffered from abdominal pain, edema distension.
Herba Plantaginis, sweet, cold.Return liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Fructus Aurantii Immaturus, bitter, pungent, sour, temperature.Return spleen, stomach warp.Dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.
Exocarpium Benincasae, sweet, cool.Return spleen, small intestine meridian.Inducing diuresis to remove edema.For edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine.
The Rhizoma Pinelliae, pungent, temperature; Poisonous.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, and vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.
The parts by weight of the present invention to above-mentioned all taste Chinese medicine carry out preferably, preferred condition be after drug matching uses medicine to the enhancing of Conditions of Pure Obesity Treatment effect.As a preferred embodiment of the present invention, medicine of the present invention is obtained by the crude drug of following weight portion: Caulis Trachelospermi 1-3 part, Spica Prunellae 4-6 part, Semen Coicis 6-8 part, Folium Sennae 1-3 part, Herba Plantaginis 17-20 part, Fructus Aurantii Immaturus 13-15 part, Exocarpium Benincasae 6-8 part, Rhizoma Pinelliae 9-11 part.
Further preferably, medicine of the present invention is obtained by the crude drug of following weight portion: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts.
For Simple Obesity, Semen Coicis, Rhizoma Pinelliae invigorating the spleen for dissipating phlegm damp eliminating in we; The convenient water of Fructus Aurantii Immaturus, Folium Sennae promote qi circulation opening; Caulis Trachelospermi, Herba Plantaginis clearing away heat and cooling blood; Spica Prunellae, Exocarpium Benincasae clearing away heat and promoting diuresis.Full side's clearing heat and expelling damp, invigorating the spleen and benefiting QI, relieving constipation diuretic, thus the remarkable result playing treatment Splenic asthenia and obstruction of dampness Simple Obesity.
In order to express medicine of the present invention better, medicine of the present invention can be prepared into dosage form conventional clinically.Such as, powder, pill, sublimed preparation, unguentum, granule, tablet, capsule.Preferably, medicine of the present invention conveniently preparation technology be prepared into granule, powder, capsule or tablet.
Present invention also offers a kind of preparation method of aforementioned pharmaceutical compositions, it mainly comprises following step: first, get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials again, make capsule etc. with conventional fabrication process.
The present invention also asks to protect the purposes of said medicine in preparation treatment Simple Obesity medicine.In clinical observation process, treatment group no matter obvious effective rate or effective percentage, all higher than matched group, obvious effective rate aspect is very remarkable especially.Visible medicine of the present invention can as the drug use for the treatment of Splenic asthenia and obstruction of dampness Simple Obesity.In treatment group therapeutic process, vital sign patient steadily and without serious adverse reactions such as allergy, show that the clinical application of we is safely and effectively.Meanwhile, compared with prior art, medicament composing prescription of the present invention is more simple, consumption is more simplified, and cost is lower, and curative effect is more definite, and preparation technology is simple to operation, is worth studying and applying further.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
EXAMPLE l
Each raw material is taken: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts by following weight portion.
Preparation method: get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials, conveniently preparation technology is prepared into capsule, and every capsules is containing crude drug 0.2g.
Embodiment 2
Each raw material is taken: Caulis Trachelospermi 1 part, Spica Prunellae 4 parts, Semen Coicis 6 parts, Folium Sennae 1 part, Herba Plantaginis 17 parts, Fructus Aurantii Immaturus 13 parts, Exocarpium Benincasae 6 parts, the Rhizoma Pinelliae 9 parts by following weight portion.
Preparation method is with embodiment 1.
Embodiment 3
Each raw material is taken: Caulis Trachelospermi 3 parts, Spica Prunellae 6 parts, Semen Coicis 8 parts, Folium Sennae 3 parts, Herba Plantaginis 20 parts, Fructus Aurantii Immaturus 15 parts, Exocarpium Benincasae 8 parts, the Rhizoma Pinelliae 11 parts by following weight portion.
Preparation method is with embodiment 1.
Embodiment 4
Each raw material is taken: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts by following weight portion.
Preparation method: get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials again, conveniently preparation technology is prepared into tablet, and every sheet is containing crude drug 0.2g.
Embodiment 5
Each raw material is taken: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts by following weight portion.
Preparation method: get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials again, conveniently preparation technology is prepared into granule, and every bag containing crude drug 2g.
Embodiment 6
Each raw material is taken: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts by following weight portion.
Preparation method: get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials again, conveniently preparation technology is prepared into powder, and every bag containing crude drug 2g.
The clinical observation of embodiment 7 Drug therapy Simple Obesity of the present invention
1, case-data: that selects hospital ward and outpatient clinic meets Splenic asthenia and obstruction of dampness Simple Obesity Patient 100 example, age 35-50 year; With reference to 2003 " Chinese Adult Overweight and obesity disease prevention and control guide (trying out) " according to Body Mass Index method BMI (kg/m
2)=body weight (kg)/[height (m)]
2.BMI is the most important index of diagnosis obesity.Overweight BMI=24 ~ 29.9, Mild Obesity BMI=30 ~ 34.9, central obesity BMI=35 ~ 39.9, severe simple obesity BMI >=40, male's waistline is more than or equal to 85cm and women's waistline, and to be more than or equal to 80cm be abdominal obesity.Splenic asthenia and obstruction of dampness disease sees obesity, spiritlessness and weakness, and limbs are heavy, abdominal distension and anorexia, and urine amount is few, and large loose stool is thin, has Mild edema during lower limb, and there is indentation on the fat limit of light red tongue, white and greasy fur, and soft pulse is sliding or slow.
Be divided into treatment group, matched group at random.Wherein, treatment group 50 example, man 20 example, female 30 example, severe simple obesity 15 example, central obesity 25 example, Mild Obesity 5 example, overweight 5 examples.Matched group 50 example, man 22 example, female 28 example, severe simple obesity 16 example, central obesity 23 example, Mild Obesity 6 example, overweight 5 examples.The physical data there was no significant differences such as two groups of Genders, age, state of an illness distributions, have comparability.
2, usage and dosage:
Treatment group: take Drug therapy of the present invention, capsule prepared by Example 1, every containing crude drug amount 0.2g, every day 3 times, each 4-5 grain, after meal half an hour warm water delivery service.
Matched group: adopt the oral fat pill for curing that disappears of making light of one's life by commiting suicide, accurate word Z11020496, the 240s*3 bottle of traditional Chinese medicines, one time 30,3 times on the one.
All treat after 2 months for two groups and carry out therapeutic evaluation.
3, curative effect determinate standard:
Effective: weight loss is more than or equal to 5kg, related conditions disappears substantially.
Effective: weight loss is more than or equal to 3kg, related conditions alleviates.
Invalid: body weight does not decline, related conditions does not alleviate.
4, therapeutic effect:
Without coming off case in clinical observation process, all complete clinical observation.Two groups of efficacy determinations the results are shown in Table 1.
Table 1 liang group efficacy determination results contrast
| Group | Effective | Effectively | Invalid | Effective percentage (%) |
| Treatment group | 21 | 28 | 1 | 98％ |
| Matched group | 15 | 18 | 17 | 66％ |
Discussion of results: treatment group no matter obvious effective rate or effective percentage, all higher than matched group, obvious effective rate aspect is more remarkable.Visible medicine of the present invention can as the drug use for the treatment of Splenic asthenia and obstruction of dampness Simple Obesity.
Claims (6)
1. treat the medicine of Simple Obesity for one kind, it is characterized in that, it is obtained by the crude drug of following weight portion: Caulis Trachelospermi 1-3 part, Spica Prunellae 4-6 part, Semen Coicis 6-8 part, Folium Sennae 1-3 part, Herba Plantaginis 17-20 part, Fructus Aurantii Immaturus 13-15 part, Exocarpium Benincasae 6-8 part, Rhizoma Pinelliae 9-11 part.
2. medicine as claimed in claim 1, it is characterized in that, it is obtained by the crude drug of following weight portion: Caulis Trachelospermi 2 parts, Spica Prunellae 5 parts, Semen Coicis 7 parts, Folium Sennae 2 parts, Herba Plantaginis 18 parts, Fructus Aurantii Immaturus 14 parts, Exocarpium Benincasae 7 parts, the Rhizoma Pinelliae 10 parts.
3. medicine as claimed in claim 1 or 2, it is characterized in that, it is tablet, capsule or granule.
4. the preparation method of a medicine as claimed in claim 1, it mainly comprises following step: first, get Caulis Trachelospermi, Spica Prunellae, Semen Coicis, Folium Sennae, Herba Plantaginis, Fructus Aurantii Immaturus, Exocarpium Benincasae, the Rhizoma Pinelliae be ground into coarse powder respectively, 8 times amount soak by water 2 times, each 1.5 hours, filter, the paste that filtrate concentrating obtains is dried to fine powder, add appropriate amount of auxiliary materials again, make each dosage form with conventional fabrication process.
5. the purposes of medicine as claimed in claim 1 or 2 in the medicine of preparation treatment Simple Obesity.
6. the purposes of medicine as claimed in claim 1 or 2 in the medicine of preparation treatment Splenic asthenia and obstruction of dampness Simple Obesity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510090037.2A CN104587304B (en) | 2015-02-27 | 2015-02-27 | A kind of medicine for the treatment of Simple Obesity and uses thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510090037.2A CN104587304B (en) | 2015-02-27 | 2015-02-27 | A kind of medicine for the treatment of Simple Obesity and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104587304A CN104587304A (en) | 2015-05-06 |
| CN104587304B true CN104587304B (en) | 2015-09-23 |
Family
ID=53113575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510090037.2A Expired - Fee Related CN104587304B (en) | 2015-02-27 | 2015-02-27 | A kind of medicine for the treatment of Simple Obesity and uses thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104587304B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816777A (en) * | 2016-05-05 | 2016-08-03 | 宋云飞 | Medicine for treating simple obesity |
| CN105963440A (en) * | 2016-06-29 | 2016-09-28 | 张燕蕾 | Traditional Chinese medicine for treating simple obesity by combining acupuncture and preparation method of traditional Chinese medicine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103768310A (en) * | 2012-10-24 | 2014-05-07 | 魏自由 | Weight-reducing traditional Chinese medicine composition |
| CN104208516A (en) * | 2014-09-26 | 2014-12-17 | 洛阳华以生物工程有限公司 | Chinese medicinal formula for treating adiposity |
-
2015
- 2015-02-27 CN CN201510090037.2A patent/CN104587304B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104587304A (en) | 2015-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104162094A (en) | Traditional Chinese medicine composition for treating obese polycystic ovary syndrome, and medicinal preparation thereof | |
| CN103623280B (en) | A kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease | |
| CN104587304B (en) | A kind of medicine for the treatment of Simple Obesity and uses thereof | |
| CN104815318A (en) | Traditional Chinese medicine preparation for treating gout | |
| CN104587302A (en) | Traditional Chinese medicine preparation for treating acute appendicitis | |
| CN105816802A (en) | Orally-taken traditional Chinese medicine preparation for treating wind heat-type common cold | |
| CN105056020A (en) | Lingxian pill for treating gout and preparation method of pill | |
| CN104398733A (en) | Traditional Chinese medicine preparation for treating liver depression and qi stagnation type thyroid cancer | |
| CN104288303A (en) | Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases | |
| CN105381441A (en) | Traditional Chinese medicine capsule for preventing and treating cyesedema and preparation method of traditional Chinese medicine capsule | |
| CN113117054A (en) | Chinese medicinal composition for treating and preventing cardiovascular and cerebrovascular diseases and preparation method thereof | |
| CN105434739A (en) | Traditional Chinese medicine composition for treating chalazia and preparation method thereof | |
| CN105213905A (en) | A kind of Chinese medicine composition and application thereof preventing and treating postmenopausal osteoporosis | |
| CN104887950A (en) | Mastitis treatment traditional Chinese medicine compound | |
| CN104873602A (en) | Traditional Chinese medicine for treating mammary gland hyperplasia | |
| CN104225016A (en) | Drug composition for treating spleen and stomach deficiency type chronic atrophic gastritis | |
| CN104306948A (en) | Medicament composition for treating gouty arthritis | |
| CN104189649A (en) | Traditional Chinese medicine composition for treating recurrent genital herpes | |
| CN104491316B (en) | A kind of Chinese medicine preparation for the treatment of deficiency of QI in middle-JIAO type hyperplasia of prostate | |
| CN103585414A (en) | Pharmaceutical composition for treating sciatica and osteoporosis | |
| CN103705857B (en) | For preventing the Chinese medicine composition of oral cavity radiomucitis | |
| CN103705856B (en) | For preventing the Chinese medicine composition of chemicotherapy acute radio-reaction | |
| CN103735778B (en) | A kind of Chinese medicine composition for the treatment of of obesity | |
| CN103285339B (en) | External medicine for treating bone pain disease | |
| CN104873896A (en) | Traditional Chinese medicine composition for treating stroke caused by hypertension |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: JIE BO Free format text: FORMER OWNER: CHEN HONG Effective date: 20150820 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Jiang Anshi Inventor after: Liu Weihong Inventor before: Chen Hong |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: CHEN HONG TO: JIANG ANSHI LIU WEIHONG |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20150820 Address after: 235162 Anhui Province, Huaibei City Xiangshan District Anhui Hengyuan coal Limited by Share Ltd dormitory Applicant after: Jie Bo Address before: 266000 Qingdao City, Sifang District, Shandong flood water ditch village, No. 2, 106 Applicant before: Chen Hong |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190814 Address after: 510080 Room 01-b, Third Floor B, Information Industry Science Park, No. 8 Helong Road, Helong Street, Baiyun District, Guangzhou City, Guangdong Province (Independent Declaration) Patentee after: Bai's Health (Guangzhou) Big Health Technology Co., Ltd. Address before: 235162 Anhui Province, Huaibei City Xiangshan District Anhui Hengyuan coal Limited by Share Ltd dormitory Patentee before: Jie Bo |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150923 Termination date: 20210227 |