CN105056020A - Lingxian pill for treating gout and preparation method of pill - Google Patents
Lingxian pill for treating gout and preparation method of pill Download PDFInfo
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Abstract
The invention discloses a Lingxian pill for treating gout and a preparation method of the pill. The Lingxian pill is mainly prepared from the following crude medicines in parts by weight: 130-150 parts of radix clematidis, 130-150 parts of glabrous greenbrier rhizome, 130-150 parts of dioscorea hypoglauca palibin, 130-150 parts of coix seed, 40-50 parts of stir-baked semen persicae, 40-50 parts of safflower, 40-50 parts of herba lycopi, 40-50 parts of semen plantaginis, 40-50 parts of rhizome of Chinese atractylodes, 40-50 parts of rhizoma alismatis, 40-50 parts of pseudobulbus cremastrae seu pleiones, 40-50 parts of polygonum cuspidatum, 40-50 parts of Indian damnacanthus herb, 20-40 parts of liquorice root and 40-50 parts of cortex phellodendri. The Lingxian pill disclosed by the invention, in treating gout, is free from toxic and side effects and is significant in treatment effect, and the total effective rate of the pill reaches 95.7%. Through clinical application for years, the Lingxian pill disclosed by the invention brings about good social and economic benefits, and the Longxian pill is capable of solving repeated attack of arthritis caused by gout and the pain of patients of hyperuricemia.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Radix Clematidis ball for the treatment of gout and preparation method thereof.
Background technology
Gout, sickness rate is high, healing is difficult, recurrent exerbation, belongs to the metabolic disease that disorders of purine metabolism causes.Gout is multiple is born in middle-aged and elderly people, overweight people and brain worker, the gouty acute arthritis recurrent exerbation that its clinical characters is antihyperuricemic and causes thus, tophaceous deposition, tophaceous chronic arthritis and joint deformity etc., dumb for main clinical manifestation with redness and swelling of joints, burning pain, recurrent exerbation, joint motion.Often involving kidney causes chronic interstitial nephritis and uric acid kidney stones to be formed.Increase reason according to uric acid in blood and can be divided into constitutional and the large class of Secondary cases two.The cause of disease of primary gout is caused by congenital purine metabolic disturbance, belongs to heritability.The cause of disease of secondary gout, can be caused by many reasons such as nephropathy, leukemia, medicine, foods, be apt to occur in male and menopausal woman.Gout belongs to Chinese medicine " arthromyodynia " category." treatise on blood trouble ": " gout, general numbness and hypoesthesia, limbs pain, modern name gout, Gu say arthromyodynia ".
At present, also do not treat the specially good effect way of gout, from the organic conception of the traditional Chinese medical science, treat with Chinese medicine integral syndrome differentiation, a good footpath for the treatment of gout of can yet be regarded as; Not only the toxic and side effects of Chinese medicine itself is little, and can reduce the side effect of taking merely Western medicine for a long time and bringing.But the Chinese patent medicine for the treatment of gout in the market also has much, and curative effect lacks preferably relatively, patient still can only carry out the stable state of an illness by taking the larger Western medicine of toxic and side effects in a large number.Drug patent document about treatment gout also has much, such as: 1, application number is 201210431071.8, name is called the patent of invention of the pharmaceutical composition of gout " treatment ", and disclosed in this patent, pharmaceutical composition is made primarily of Folium Perillae, Radix Ranunculi Ternati, Rhizoma Chuanxiong and Radix Glycyrrhizae.2, application number 201210428551.9, name are called the patent of invention of " pharmaceutical composition for the treatment of gout ", and disclosed in this patent, pharmaceutical composition is made primarily of crude drug such as Fructus Citri Sarcodactylis, Radix Salviae Miltiorrhizae, Herba Epimedii.
Summary of the invention
The technical problem to be solved in the present invention is: provide a kind of Radix Clematidis ball for the treatment of gout and preparation method thereof.Utilize Drug therapy gout of the present invention, its therapeutic effect is remarkable; Go through several years checking, determined curative effect.Medicament composing prescription of the present invention based on expelling wind and removing dampness eliminating impediment, because of " prolonged illness is from the stasis of blood ", " all kinds of diseases and ailments are many to be haunted by expectorant ", therefore coordinate the stasis of blood of living, reduce phlegm, the product of removing toxic substances and curative effect is distinguished.Radix Clematidis ball of the present invention, through clinical research for many years, effectively can solve the misery of arthritis recurrent exerbation caused by gout and hyperuricemia patients.
In order to solve the problem, the technical scheme that the present invention takes is:
The invention provides a kind of Radix Clematidis ball for the treatment of gout, represent with weight portion, described Radix Clematidis ball is made primarily of crude drug Radix Clematidis 130 ~ 150 parts, Rhizoma Smilacis Glabrae 130 ~ 150 parts, Rhizoma Dioscoreae Hypoglaucae 130 ~ 150 parts, Semen Coicis 130 ~ 150 parts, Semen Persicae (parched) 40 ~ 50 parts, 40 ~ 50 parts, Flos Carthami, Herba Lycopi 40 ~ 50 parts, Semen Plantaginis 40 ~ 50 parts, Rhizoma Atractylodis 40 ~ 50 parts, Rhizoma Alismatis 40 ~ 50 parts, Pseudobulbus Cremastrae Seu Pleiones 40 ~ 50 parts, Rhizoma Polygoni Cuspidati 40 ~ 50 parts, Herba Damnacanthi 40 ~ 50 parts, 20 ~ 40 parts, Radix Glycyrrhizae and Cortex Phellodendri 40 ~ 50 parts.
According to the Radix Clematidis ball of above-mentioned treatment gout, described Radix Clematidis ball is made primarily of crude drug Radix Clematidis 135 ~ 145 parts, Rhizoma Smilacis Glabrae 135 ~ 145 parts, Rhizoma Dioscoreae Hypoglaucae 135 ~ 145 parts, Semen Coicis 135 ~ 145 parts, Semen Persicae (parched) 43 ~ 48 parts, 43 ~ 48 parts, Flos Carthami, Herba Lycopi 42 ~ 47 parts, Semen Plantaginis 43 ~ 47 parts, Rhizoma Atractylodis 43 ~ 48 parts, Rhizoma Alismatis 43 ~ 48 parts, Pseudobulbus Cremastrae Seu Pleiones 43 ~ 47 parts, Rhizoma Polygoni Cuspidati 42 ~ 47 parts, Herba Damnacanthi 43 ~ 48 parts, 25 ~ 35 parts, Radix Glycyrrhizae and Cortex Phellodendri 44 ~ 48 parts.
In addition, provide a kind of preparation method for the treatment of the Radix Clematidis ball of gout, described preparation method comprises the following steps:
A, first take various crude drug according to the ratio of above-mentioned treatment gout Radix Clematidis ball, the various crude drug taken are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders;
B, then add the ratio of starch 23 ~ 28g, microcrystalline Cellulose 1.5 ~ 2.0g respectively according to every 1000g mixing fine powders, add starch, microcrystalline Cellulose mix homogeneously, the ratio adding 380 ~ 420g according to every 1000g mixing fine powders after mixing adds water, stirs and makes soft material after 20 ~ 30 minutes;
C, the soft material made by step b are placed in pellet processing machine and make the wet ball that diameter is 4.0 ~ 4.3mm;
D, that the ball that to be wet by step c gained is placed in microwave drying sterilization case is dry, dry ball moisture content≤8% of gained after dry;
E, dry for steps d gained ball is placed in coating pan bag charcoal clothing, polishing, the Radix Clematidis ball of the gout that obtains medical treatment.
According to the preparation method of the Radix Clematidis ball of above-mentioned treatment gout, add starch 26g respectively according to every 1000g mixing fine powders in step b, the ratio of microcrystalline Cellulose 1.8g adds starch, microcrystalline Cellulose mix homogeneously; The ratio adding water 400g according to every 1000g mixing fine powders adds water.
The present invention treats the medicine of gout, conventionally can make decoction take according to pharmaceutical formulation.
the pharmacological action of the various crude drug of the present invention:
Radix Clematidis: this product acrid in the mouth is salty, warm in nature, poisonous; Enter urinary bladder channel.Effect: this product has expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the effects such as the loose hypochondriac lump; Commonly use and control gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, the cards such as all a fishbone or other bone caught in the throat pharynxs.
Rhizoma Smilacis Glabrae: this product slightly sweet flavor, property is put down; Return Liver Channel, stomach warp and spleen channel.Effect: this product has removing toxic substances, dehumidifying, the effects such as sharp joint; Commonly use and control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, furuncle treats skin ulcer, carbuncle, scrofula, syphilis and the limbs contracture caused by mercurialism, the cards such as bones and muscles pain.
Modern medicine study: this product rhizome is containing Saponin, tannin, resin etc.There is antitumor action and the Detoxication to gossypol.
Rhizoma Dioscoreae Hypoglaucae: this product bitter in the mouth, property are flat, returns Liver Channel, stomach warp, urinary bladder channel.Effect: this product has diuretic, dispels the wind, the effects such as dampness removing; Conventional dispelling the wind and dampness pathogens insensitive impediment, lumbocrural pain, dysuria, stranguria with turbid discharge, seminal emission, the cards such as damp and hot sore.
Semen Coicis: this product slightly sweet flavor, cool in nature, returns spleen channel, stomach warp and lung meridian.Effect: this product has spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, the effects such as diuretic; This moral character is partially cold and cool, is longer than promoting diuresis to eliminate damp pathogen, clearing away heat and discharging pus, eliminating impediment pain relieving; Be usually used in dysuria, edema, beriberi, lung abscess, acute appendicitis, rheumatic arthralgia, the cards such as muscle arteries and veins contraction urgency and warm and humid disease.
Semen Persicae: bitter in the mouth, sweet, property is put down; Enter the heart, liver, large intestine channel.This product has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, the effects such as relieving cough and asthma.Commonly use and control amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, the cards such as dryness of the intestine constipation.
Semen Persicae (parched): this product has the effect of good blood stasis removing and clots absorbing, simultaneously also can moisturize laxation, can treat amenorrhea and dysmenorrhea with Semen Persicae (parched), for the effect of traumatic injury and dryness of the intestine constipation; This product also have preferably health care Secrete and, Semen Persicae (parched) can stomach invigorating, also can enrich blood, also have good lung moistening effect simultaneously, can repose, have good QI invigorating Secrete and effect; This product can allow people's life lengthening, has well profit flesh effect simultaneously, can black beard and hair, has good diuretic effect, can go five hemorrhoid; Can benefiting qi and nourishing blood, simultaneously also can moistening the lung and resolving the phlegm.
Flos Carthami: acrid in the mouth, warm in nature, enters the heart, Liver Channel.Effect: this product has promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, traumatic injury, skin infection such as to swell and ache at the card.
Modern medicine study proves: this product is containing carthamin, neocarthamin, Flos Carthami quinone glycoside, Flos Carthami polysaccharide, Palmic acid, cinnamic acid, lauric acid etc.There is the effects such as blood pressure lowering, blood vessel dilating, anticoagulation, resisting fatigue, analgesia and calmness.
Herba Lycopi: this product bitter in the mouth, pungent, slightly warm in nature; Effect: the effects such as this product has blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema; Commonly use and control blood stasis amenorrhea, dysmenorrhea, lump in the abdomen, postnatal blood stasis is suffered from abdominal pain, body and face edema, injury from falling down, gold wound, sore and toxic, edema, the cards such as ascites.
Semen Plantaginis: this product sweet in the mouth, light, cold nature; Return lung, liver, kidney, urinary bladder channel.Effect: this product has clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, improving eyesight, the effect such as to eliminate the phlegm.Conventional control main dysuria, stranguria with turbid discharge leukorrhagia, edema distension, heat-damp in summer dysentery, conjunctival congestion is hidden from view, and expectorant heat syndrome cough such as to breathe heavily at the card.
Modern medicine study: Herba Plantaginis seed contains moon aucubin, Herba Plantaginis mucopolysaccharide, racemization-plantagoside, all square rafter glycoside acid, plantenolic acid, succinic acid, adenine, choline and 10.43% fatty oil, the black alcohol of β-paddy, cupreol-3-O-β-D-glucopyanoside.This product has diuresis, intends choline effect, eliminates the phlegm, antitussive, antiasthmatic effect, and resisting pathogenic microbes effect, has regulating action to gastrointestinal function, obvious spasmolysis etc.
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature; Enter spleen, stomach, Liver Channel.This product has drying damp and strengthening spleen, expelling wind and cold, the effects such as improving eyesight.Commonly use and control distension and fullness in the abdomen, edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, the cards such as nyctalopia; Cure mainly the spleen and stomach being stranded by dampness, asthenia drowsiness, born of the same parents' painful abdominal mass abdominal distention, inappetence, tells and has loose bowels, phlegm retention, damp-edema, and exterior syndrome folder is wet, head heavy sensation of the body pain, arthromyodynia warm nature, the cards such as podomere is ached and weighed, flaccidity folds in a garment.
Modern pharmacology research proves: this product has adjustment gastrointestinal motility function, antiulcer, protect the liver, antibacterial, the pharmacological action that promotes skeleton calcification, antitumor, blood pressure lowering, anti-hypoxia.
Rhizoma Alismatis: cold in nature, sweet in the mouth, light; Enter kidney, bladder two warp.Effect: 1, promoting diuresis to eliminate damp pathogen: this product slightly sweet flavor and cold in nature, the cold diarrhea of heat type water that can win, the light diuretic that can ooze wets.Enter urinary bladder channel, the water being good at oozing sharp bladder wets.Conventional this product treatment dysuria, in water, has loose bowels, stranguria with turbid discharge, leukorrhagia, phlegm retention etc.2, expel the heat-evil: Rhizoma Alismatis is cold in nature, cold can heat clearing away, enter kidney channel, then it is mutually fiery to rush down kidney channel, can be used for deficiency of kidney yin, the seminal emission of mutually fiery high Sheng, tinnitus, the card such as dizzy.3, clever knowledge: Rhizoma Alismatis is sweet light cold in nature, energy promoting diuresis to eliminate damp pathogen, lets out clearly fire mutually.Rhizoma Alismatis has foster the five internal organs, physical strength profiting, controls head and revolves, the merit of clever knowledge.Therefore availablely control the cards such as tinnitus, blurred vision, dizziness.
Pseudobulbus Cremastrae Seu Pleiones: this product sweet in the mouth, micro-pungent, cool in nature; Return Liver Channel, stomach warp, spleen channel.Effect: this product has heat-clearing and toxic substances removing, the effects such as eliminating carbuncle eliminating stagnation; Commonly use and control carbuncle furunculosis, scrofula sucutaneous nodule, snake bite and insect sting, the cards such as lame abdominal mass mass in the abdomen.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature.Enter liver, gallbladder, lung meridian.This product has heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, the effects such as relieving cough and resolving phlegm.Commonly use and control arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, the cards such as carbuncle sore tumefacting virus.
Modern pharmacology research proves: this product contains knotweed glycoside, organic acid, glycoside, polysaccharide etc.The pharmacological action had is blood pressure lowering, protects the liver, antibacterial, antiviral, antitussive and antiasthmatic, antitumor, blood sugar lowering, blood fat reducing, hemostasis, the effects such as antipyretic-antalgic.
Herba Damnacanthi: this product sweet in the mouth, property is put down.Effect: the effects such as this product has expelling wind and removing dampness, promoting blood circulation and detumescence; Commonly use and control gout, rheumatic arthralgia, cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, the cards such as traumatic injury.
Radix Glycyrrhizae: property is flat, sweet in the mouth, enters 12 warps.Effect: Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the functions such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, distension and fullness in the abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Modern pharmacology research proves: Radix Glycyrrhizae contains number of chemical composition, and main component has glycyrrhizic acid, liquiritin etc.There is antiinflammatory, antiviral, the effects such as protecting liver and detoxication and enhancing immunologic function.Because glycyrrhizic acid has the pharmacological action of glucocorticoid sample without serious adverse reaction, be clinically widely used in treating various acute, chronic hepatitis, bronchitis and acquired immune deficiency syndrome (AIDS), also there is the functions such as anti-cancer and cancer-preventing, interferon inducer and cell immunomodulator.Glycyrrhizic acid has blood fat reducing and study of anti-atherogenic effect, stops atherosclerotic formation.
Cortex Phellodendri: this product bitter in the mouth, cold in nature; Enter kidney, bladder, large intestine channel.Effect: this product has heat clearing and damp drying, pathogenic fire purging removes steams, the effects such as detoxification sore treatment.Commonly use and control damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive disease heat, night sweat, seminal emission, sore swollen toxin, the diseases such as eczema pruritus.
Chinese medical discrimination: damp-heat accumulation type gout, residence place is moist, drenches with rain and paddles, experience exogenous damp, long-pending wet with the passing of time, strongly fragrant and generate heat, or dysfunction of the spleen, water wets cohesion, leads to damp and hot.Radix Clematidis wind-damp dispelling, the meridian dredging, stopping numbness pain, controls a fishbone or other bone caught in the throat, " book on Chinese herbal medicine justice ": " Radix Clematidis, disappear gram for what one is particularly good to walk to alter, long-pending wet retention of phlegm, the blood clotting stagnation of QI, all realities should it.", Rhizoma Atractylodis are drying damp and strengthening spleen, wind-damp dispelling." pearl sac " " stomach invigorating can pacify spleen, non-this of all damp-edema can not remove." the two mutually auxiliary be use, be monarch drug altogether; Rhizoma Dioscoreae Hypoglaucae dampness removing is turbid, wind-damp dispelling." herbal classic ": " main lumbago and backache is strong, joint wind and cold general arthralgia, and malignant boil is Liao not, steam ".Semen Coicis promoting diuresis to eliminate damp pathogen, spleen invigorating eliminating impediment, clearing away heat and discharging pus." herbal classic ": " main muscular contracture contracture, unable to flex and stretch the extremities, rheumatism numbness, the therapeutic method to keep the adverse QI flowing downwards." the two is mutually auxiliary, is ministerial drug altogether; Semen Persicae (parched) blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation." herbal classic ": " main blood stasis, blood closes abdominal mass, pathogen, kills small worm ", Flos Carthami blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow.Compendium of Material Medica: " invigorate blood circulation and moisturize, pain-relieving powder for treating swells, and stimulates the menstrual flow ".Rhizoma Smilacis Glabrae detoxifies, dehumidifying, sharp joint.Essentials of Matea Medica: " control syphilitic sore, scrofula skin ulcer swells " Herba Lycopi's blood circulation promoting and blood stasis dispelling, line water detumescence.Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, expels the heat-evil.Compendium of Material Medica: " eliminating dampness by diuresis heat, row phlegm retention, anti-nausea, dysentery, colic, beriberi.Zhong Jing Dihuang Wan, with Poria, Rhizoma Alismatis person, be get the pathogen that it rushes down bladder, non-drawing connects also." Semen Plantaginis relieving stranguria by diuresis, antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm." herbal classic ": " dredging water passages urine, except arthralgia chiefly caused by damp pathogen for main stranguria due to disorder of QI, pain relieving." Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever.Pseudobulbus Cremastrae Seu Pleiones heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Herba Damnacanthi expelling wind and removing dampness, promoting blood circulation and stopping pain, Rhizoma Polygoni Cuspidati is invigorated blood circulation analgesic therapy, clearing away heat-damp and promoting diuresis, removing toxic substances, preventing phlegm from forming and stopping coughing.All medicines above, Xiang Fuwei use is adjuvant drug altogether; Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription, for making medicine.
Total sight is side entirely, and with clearing away heat-damp and promoting diuresis, removing obstruction in the collateral to relieve pain is main, and focus on the damp-heat accumulation of correction caused by deficiency of spleen-YANG and kidneyYANG in joint, cause arthralgia, deficiency of QI with disinclination to talk, separately with invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral, channels sootheing and network vessel quickening is to consolidate, and reinforcement and elimination in combination, treating both the principal and the secondary aspects of a disease at the same time, hit pathogenesis.
positive beneficial effect of the present invention:
1, utilize Radix Clematidis pill for curing gout of the present invention, its treatment does not have toxic and side effects, and therapeutic effect is remarkable, and total effective rate reaches 95.7%.
2, medicament composing prescription of the present invention is with clearing away heat-damp and promoting diuresis, and removing obstruction in the collateral to relieve pain is main; Focus on the damp-heat accumulation of correction caused by deficiency of spleen-YANG and kidneyYANG in joint, cause arthralgia, deficiency of QI with disinclination to talk, separately with invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral, channels sootheing and network vessel quickening is to consolidate, and reinforcement and elimination in combination, treating both the principal and the secondary aspects of a disease at the same time, hit pathogenesis.
3, Radix Clematidis ball of the present invention is mainly used in arthritis recurrent exerbation caused by gout and hyperuricemia.Disease sees arthralgia, joint stuffiness, pain or migration or to weigh or violent, meets wind and cold, humidity, sombrely increases the weight of.Arthralgia, does not with the passing of time heal, or arthroncus deformity, around tuberosity, the dermal ecchymosis.
4, Radix Clematidis ball of the present invention employs for many years in clinical, creates good Social benefit and economic benefit, solves the misery of arthritis recurrent exerbation caused by gout and hyperuricemia patients.
1) social benefit: Radix Clematidis ball of the present invention, in clinical middle determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, is dissolved by the cause of disease, generally takes medicine 10
After it, patients clinical symptom alleviates, pain relief, blood uric acid reduces, effectively shorten the treatment time of patient, alleviate the sufferings of patient, the perfect therapeutic scheme of goat, also on the therapeutic effect of goat, obtain further raising, create certain social influence and public praise publicity.
2) economic benefit: Radix Clematidis ball of the present invention applies to clinical, efficiently solves the slight illness of most of goat patient, and curative effect is given prominence to, economical cheap, and patient is easy to accept, and highlights Chinese medicine characteristic simultaneously, also creates certain economic benefit.
3) potential benefit: goat is with hyperuricemia, characteristic acute arthritis recurrent exerbation for clinical characters, and Chang Yi involves kidney, is mainly seen in middle-aging male, eating condition superior easily suffers from this disease, there is no radical cure method at present.My institute is inquired into by the clinical observation of nearly 10 years, etiology and pathogenesis and is summed up, and Radix Clematidis ball of the present invention, if be widely used in clinical, will bring glad tidings to numerous goat patient, the economic benefit also brought to hospital and social benefit.
5, for many years, utilize Radix Clematidis pill for curing patient with gout many cases of the present invention, carried out detail statistics to the treatment situation of wherein 300 routine patients, statistics refers to table 1, table 2.
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The diagnostic criteria of gout:
1, Western medicine diagnose standard: with reference to 1977 Americanism damp disease association (ACR) criteria for classification.
(1) specific urate crystal body is had in joint fluid.
(2) have tophus, chemically (murexide test) or polarized light microscope observing confirm containing urate crystal.
(3) 6 persons in following clinical, laboratory and x-ray sign etc. 12 are possessed:
A, more than 1 time acute arthritis outbreak;
B, inflammation show in l day and peak;
C, monarthritis are shown effect;
D, observe joint redness;
E, Metatarsophalangeal joint pain or swelling;
Metatarsophalangeal joint is involved in f, one-sided outbreak;
Midtarsal joints is involved in g, one-sided outbreak;
H, suspicious tophus;
J, hyperuricemia;
K, intraarticular asymmetry swelling (x line sheet);
L, do not accompany bone erosion cortical bone under cyst (x line sheet);
M, between arthritis stage of attack, joint fluid microorganism culturing is negative;
In above-mentioned (1), (2), (3) item, possess that any one is namely diagnosable.
Therapeutic Method: patient with gout is taken the present invention and treated gout Radix Clematidis ball Chinese patent medicine pill (namely the present invention treats the Chinese patent medicine of gout, its dosage form is pill), the prescription of employing is: Radix Clematidis 130 ~ 150g, Rhizoma Smilacis Glabrae 130 ~ 150g, Rhizoma Dioscoreae Hypoglaucae 130 ~ 150g, Semen Coicis 130 ~ 150g, Semen Persicae (parched) 40 ~ 50g, Flos Carthami 40 ~ 50g, Herba Lycopi 40 ~ 50g, Semen Plantaginis 40 ~ 50g, Rhizoma Atractylodis 40 ~ 50g, Rhizoma Alismatis 40 ~ 50g, Pseudobulbus Cremastrae Seu Pleiones 40 ~ 50g, Rhizoma Polygoni Cuspidati 40 ~ 50g, Herba Damnacanthi 40 ~ 50g, Radix Glycyrrhizae 20 ~ 40g and Cortex Phellodendri 40 ~ 50g.
The instructions of taking of Radix Clematidis ball of the present invention: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.
Take Chinese patent medicine Radix Clematidis ball criterion of therapeutical effect of the present invention:
1, curative effect of disease criterion:
(1) clinical remission: cardinal symptom disappears substantially, main laboratory indexes recovers normal.
(2) effective: cardinal symptom takes a turn for the better, and main laboratory indexes is tending towards normal.
(3) effective: cardinal symptom makes moderate progress, and main laboratory indexes numerical value declines to some extent.
(4) invalid: not reach above-mentioned effective standard or add severe one.
2, therapeutic effect of syndrome criterion:
(1) clinical recovery: tcm clinical practice symptom, sign disappear or substantially disappear, syndrome integral reduces >=95%.(2) effective: tcm clinical practice symptom, sign are obviously improved, syndrome integral reduces >=70%.
(3) effective: tcm clinical practice symptom, sign all take a favorable turn, syndrome integral reduces >=30%.
(4) invalid: tcm clinical practice symptom, sign are all not improved, even increase the weight of, syndrome integral reduces
Less than 30%.
Note: computing formula (nimodipine point system) is: [before (before treatment the rear integration of integration-treatment) ÷ treatment integration] × 100%.
Utilized the curative effect situation of the routine patient with gout of Radix Clematidis pill for curing 300 of the present invention from table 1, table 2, utilize Radix Clematidis pill for curing gout of the present invention, its therapeutic effect is remarkable, and total effective rate reaches 95.7%.
model case:
1, Lee, man, 42 years old, is chief complaint with " left sufficient Metatarsophalangeal joint swells and ache about half a year ", to our hospital on March 12nd, 2014, time disease see: left sufficient Metatarsophalangeal joint congestion and swelling pain, tenderness, walk difficulty, obesity, stool is normal, oliguria with reddish urine, red tongue yellow and greasy fur, slippery and rapid pulse; Be diagnosed as " gout ".Radix Clematidis ball of the present invention is taken in therapeutic process, the prescription of this pill is: the instructions of taking of Radix Clematidis 130g, Rhizoma Smilacis Glabrae 130g, Rhizoma Dioscoreae Hypoglaucae 130g, Semen Coicis 130g, Semen Persicae (parched) 46g, Flos Carthami 46g, Herba Lycopi 46g, Semen Plantaginis 46g, Rhizoma Atractylodis 46g, Rhizoma Alismatis 46g, Pseudobulbus Cremastrae Seu Pleiones 46g, Rhizoma Polygoni Cuspidati 46g, Herba Damnacanthi 46g, Radix Glycyrrhizae 27g and Cortex Phellodendri 46g(Radix Clematidis ball: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.Take Chinese patent medicine of the present invention (Radix Clematidis ball) treat 1 the course for the treatment of rear left foot Metatarsophalangeal joint to swell and ache disappearance.Continue to take medicine Chinese patent medicine of the present invention (Radix Clematidis ball) 1 after treatment course for the treatment of, tcm symptom sign is obviously improved, and now normally works.
2, Wang, man, 44 years old, be chief complaint with " two ankle joint swell and ache recurrent exerbation more than 6 years, increase the weight of February ", to our hospital on May 3rd, 2014, patient often in tired and diet is careless time outbreak, through looking into medicines such as taking colchicine, allopurinol, antibiotic medicine, though can ease the pain, a few free of discontinuities of showing effect.Within nearly 2 months, right ankle joint continues swelling, takes medicine and cannot alleviate, and affected part tenderness is obvious, and the colour of skin is dark red, and that lays one's hand on is slightly hot, can not walking for a long time, diet still can, two just can, poor sleep (because of pain), body of the tongue is light red, and corpulent tongue is large, while there is indentation, thick fur is slightly yellow, stringy and thready pulse; Be diagnosed as " gout ".To our hospital afterwards, Radix Clematidis ball of the present invention is taken in therapeutic process, the prescription of this pill is: the instructions of taking of Radix Clematidis 140g, Rhizoma Smilacis Glabrae 140g, Rhizoma Dioscoreae Hypoglaucae 140g, Semen Coicis 140g, Semen Persicae (parched) 50g, Flos Carthami 50g, Herba Lycopi 50g, Semen Plantaginis 50g, Rhizoma Atractylodis 50g, Rhizoma Alismatis 50g, Pseudobulbus Cremastrae Seu Pleiones 50g, Rhizoma Polygoni Cuspidati 50g, Herba Damnacanthi 50g, Radix Glycyrrhizae 30g and Cortex Phellodendri 46g(Radix Clematidis ball: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.Take Chinese patent medicine of the present invention (Radix Clematidis ball) treat 2 courses for the treatment of after two ankle swell and ache and obviously alleviate, sleep is greatly improved.After continuing to take 2 courses for the treatment of of medicine Chinese patent medicine of the present invention (Radix Clematidis ball) two ankle mobility comparatively before improve.Doctor's symptom and sign obviously improves, and existing basic living is taken care of oneself.
3, Korea Spro, female, 52 years old, be chief complaint with " toe, articulations digitorum manus swell and ache 5 years repeatedly, increase the weight of 2 years ", to our hospital on 08 7th, 2013, there is finger toes arthralgia without obvious inducement before 5 years in patient, night, pain was very, right hand articulations digitorum manus diabrosis 2 years, disease is seen: right hand forefinger middle finger swells and ache diabrosis, also swells and ache more very inside left hallux; Night, pain was heavier, bitter taste, and body of the tongue is light red, and corpulent tongue is large, while there is indentation, and yellow and greasy fur, wiry and frequent pulse.Blood uric acid: 714umol/L, is diagnosed as " gout ".To our hospital, take the Radix Clematidis ball that the present invention treats gout in therapeutic process and (namely treat the Chinese patent medicine of gout, its dosage form is pill), the prescription of Radix Clematidis ball is: the instructions of taking of Radix Clematidis 145g, Rhizoma Smilacis Glabrae 145g, Rhizoma Dioscoreae Hypoglaucae 145g, Semen Coicis 145g, Semen Persicae (parched) 45g, Flos Carthami 45g, Herba Lycopi 45g, Semen Plantaginis 45g, Rhizoma Atractylodis 45g, Rhizoma Alismatis 45g, Pseudobulbus Cremastrae Seu Pleiones 45g, Rhizoma Polygoni Cuspidati 45g, Herba Damnacanthi 45g, Radix Glycyrrhizae 25g and Cortex Phellodendri 50g(Radix Clematidis ball: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.Take Chinese patent medicine of the present invention (Radix Clematidis ball) and treat pain relief after 3 courses for the treatment of, the secretions of diabrosis place reduces to some extent, continue to take pain after 4 courses for the treatment of of medicine Chinese patent medicine of the present invention (Radix Clematidis ball), diabrosis remission, tcm symptom sign is obviously improved, and existing basic living is taken care of oneself.
4, hole, man, 56 years old, be chief complaint with " sudden right sufficient metatarsophalangeal joints pain about 3 days ", to our hospital on July 26th, 2013,3 days causes food seafood, drink after to happen suddenly right sufficient metatarsophalangeal joints congestion and swelling pain, swell and ache night more so, irritated, joint stuffiness, yellow urine is few, is hard and dry, yellowish fur, slippery and rapid pulse is diagnosed as " gout ".Take the Radix Clematidis ball that the present invention treats gout in therapeutic process and (namely treat the Chinese patent medicine of gout, its dosage form is pill), the prescription of this pill is: Radix Clematidis 135g, Rhizoma Smilacis Glabrae 135g, Rhizoma Dioscoreae Hypoglaucae 135g, Semen Coicis 135g, Semen Persicae (parched) 50g, Flos Carthami 50g, Herba Lycopi 50g, Semen Plantaginis 50g, Rhizoma Atractylodis 50g, Rhizoma Alismatis 50g, Pseudobulbus Cremastrae Seu Pleiones 50g, Rhizoma Polygoni Cuspidati 50g, Herba Damnacanthi 50g, Radix Glycyrrhizae 25g and Cortex Phellodendri 44g(instructions of taking: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.Take Chinese patent medicine of the present invention (Radix Clematidis ball) and treat 1 the rear right foot malaise symptoms disappearance course for the treatment of.Continue to take medicine Chinese patent medicine of the present invention (Radix Clematidis ball) 1 after treatment course for the treatment of, right sufficient mobility is normal, and tcm symptom sign is obviously improved, and now normally works.
5, week certain, man, 55 years old, be chief complaint with " toe articulations digitorum manus swells and ache 3 years repeatedly; increase the weight of 1 year ", patient often went on business before 3 years, again and again drank, enter Sorghum vulgare Pers. savoury repeatly, furthermore weariness from a tiring journey, be affected by the cold, time sense finger toes swell and ache, do not take notice of because work is comparatively busy, later often in drinking, tired or after catching cold, namely the pain increased in sense, and night, more so within 1 year, front right pointed near-end diabrosis, secrete white fat shape secretions, blood uric acid: 918umol/L, is diagnosed as gout.The Radix Clematidis ball Chinese patent medicine pill that the present invention treats gout is taken in therapeutic process, the prescription of pill is: the instructions of taking of Radix Clematidis 138g, Rhizoma Smilacis Glabrae 138g, Rhizoma Dioscoreae Hypoglaucae 138g, Semen Coicis 138g, Semen Persicae (parched) 46g, Flos Carthami 46g, Herba Lycopi 46g, Semen Plantaginis 46g, Rhizoma Atractylodis 46g, Rhizoma Alismatis 46g, Pseudobulbus Cremastrae Seu Pleiones 46g, Rhizoma Polygoni Cuspidati 46g, Herba Damnacanthi 46g, Radix Glycyrrhizae 27g and this pill of Cortex Phellodendri 46g(: 3 times on the one, a 6g, warm water delivery service; It within 30 days, is a course for the treatment of.Take Chinese patent medicine of the present invention (Radix Clematidis ball) treat 2 the course for the treatment of hallux articulations digitorum manus pain alleviate to some extent, function is slightly improved, the right hand diabrosis punishment secretion obviously reduce.Continue to take medicine Chinese patent medicine of the present invention (Radix Clematidis ball) 2 all malaise symptoms of the hallux articulations digitorum manus course for the treatment of substantially to disappear, the right hand refers to that diabrosis place wound has been received tcm symptom sign and obviously improved, and now normally works.
detailed description of the invention:
Set forth the present invention further below in conjunction with embodiment, but do not limit content of the present invention.
Embodiment 1:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 130g, Rhizoma Smilacis Glabrae 130g, Rhizoma Dioscoreae Hypoglaucae 130g, Semen Coicis 130g, Semen Persicae (parched) 46g, Flos Carthami 46g, Herba Lycopi 46g, Semen Plantaginis 46g, Rhizoma Atractylodis 46g, Rhizoma Alismatis 46g, Pseudobulbus Cremastrae Seu Pleiones 46g, Rhizoma Polygoni Cuspidati 46g, Herba Damnacanthi 46g, Radix Glycyrrhizae 27g and Cortex Phellodendri 46g.
Embodiment 2:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 138g, Rhizoma Smilacis Glabrae 138g, Rhizoma Dioscoreae Hypoglaucae 138g, Semen Coicis 138g, Semen Persicae (parched) 46g, Flos Carthami 46g, Herba Lycopi 46g, Semen Plantaginis 46g, Rhizoma Atractylodis 46g, Rhizoma Alismatis 46g, Pseudobulbus Cremastrae Seu Pleiones 46g, Rhizoma Polygoni Cuspidati 46g, Herba Damnacanthi 46g, Radix Glycyrrhizae 27g and Cortex Phellodendri 46g.
Embodiment 3:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 140g, Rhizoma Smilacis Glabrae 140g, Rhizoma Dioscoreae Hypoglaucae 140g, Semen Coicis 140g, Semen Persicae (parched) 50g, Flos Carthami 50g, Herba Lycopi 50g, Semen Plantaginis 50g, Rhizoma Atractylodis 50g, Rhizoma Alismatis 50g, Pseudobulbus Cremastrae Seu Pleiones 50g, Rhizoma Polygoni Cuspidati 50g, Herba Damnacanthi 50g, Radix Glycyrrhizae 30g and Cortex Phellodendri 46g.
Embodiment 4:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 145g, Rhizoma Smilacis Glabrae 145g, Rhizoma Dioscoreae Hypoglaucae 145g, Semen Coicis 145g, Semen Persicae (parched) 45g, Flos Carthami 45g, Herba Lycopi 45g, Semen Plantaginis 45g, Rhizoma Atractylodis 45g, Rhizoma Alismatis 45g, Pseudobulbus Cremastrae Seu Pleiones 45g, Rhizoma Polygoni Cuspidati 45g, Herba Damnacanthi 45g, Radix Glycyrrhizae 25g and Cortex Phellodendri 50g.
Embodiment 5:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 135g, Rhizoma Smilacis Glabrae 135g, Rhizoma Dioscoreae Hypoglaucae 135g, Semen Coicis 135g, Semen Persicae (parched) 50g, Flos Carthami 50g, Herba Lycopi 50g, Semen Plantaginis 50g, Rhizoma Atractylodis 50g, Rhizoma Alismatis 50g, Pseudobulbus Cremastrae Seu Pleiones 50g, Rhizoma Polygoni Cuspidati 50g, Herba Damnacanthi 50g, Radix Glycyrrhizae 25g and Cortex Phellodendri 44g.
Embodiment 6:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 135g, Rhizoma Smilacis Glabrae 135g, Rhizoma Dioscoreae Hypoglaucae 135g, Semen Coicis 135g, Semen Persicae (parched) 45g, Flos Carthami 48g, Herba Lycopi 45g, Semen Plantaginis 42g, Rhizoma Atractylodis 45g, Rhizoma Alismatis 42g, Pseudobulbus Cremastrae Seu Pleiones 45g, Rhizoma Polygoni Cuspidati 45g, Herba Damnacanthi 45g, Radix Glycyrrhizae 30g and Cortex Phellodendri 48g.
Embodiment 7:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 140g, Rhizoma Smilacis Glabrae 140g, Rhizoma Dioscoreae Hypoglaucae 140g, Semen Coicis 140g, Semen Persicae (parched) 42g, Flos Carthami 42g, Herba Lycopi 48g, Semen Plantaginis 47g, Rhizoma Atractylodis 42g, Rhizoma Alismatis 48g, Pseudobulbus Cremastrae Seu Pleiones 42g, Rhizoma Polygoni Cuspidati 48g, Herba Damnacanthi 42g, Radix Glycyrrhizae 35g and Cortex Phellodendri 42g.
Embodiment 8:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 145g, Rhizoma Smilacis Glabrae 150g, Rhizoma Dioscoreae Hypoglaucae 145g, Semen Coicis 150g, Semen Persicae (parched) 50g, Flos Carthami 50g, Herba Lycopi 50g, Semen Plantaginis 50g, Rhizoma Atractylodis 50g, Rhizoma Alismatis 50g, Pseudobulbus Cremastrae Seu Pleiones 50g, Rhizoma Polygoni Cuspidati 50g, Herba Damnacanthi 48g, Radix Glycyrrhizae 40g and Cortex Phellodendri 50g.
Embodiment 9:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 150g, Rhizoma Smilacis Glabrae 145g, Rhizoma Dioscoreae Hypoglaucae 150g, Semen Coicis 145g, Semen Persicae (parched) 48g, Flos Carthami 47g, Herba Lycopi 42g, Semen Plantaginis 45g, Rhizoma Atractylodis 48g, Rhizoma Alismatis 45g, Pseudobulbus Cremastrae Seu Pleiones 48g, Rhizoma Polygoni Cuspidati 42g, Herba Damnacanthi 50g, Radix Glycyrrhizae 25g and Cortex Phellodendri 40g.
Embodiment 10:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 132g, Rhizoma Smilacis Glabrae 132g, Rhizoma Dioscoreae Hypoglaucae 132g, Semen Coicis 132g, Semen Persicae (parched) 40g, Flos Carthami 40g, Herba Lycopi 40g, Semen Plantaginis 40g, Rhizoma Atractylodis 40g, Rhizoma Alismatis 40g, Pseudobulbus Cremastrae Seu Pleiones 40g, Rhizoma Polygoni Cuspidati 40g, Herba Damnacanthi 40g, Radix Glycyrrhizae 20g and Cortex Phellodendri 40g.
Embodiment 11:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 135g, Rhizoma Smilacis Glabrae 135g, Rhizoma Dioscoreae Hypoglaucae 135g, Semen Coicis 135g, Semen Persicae (parched) 43g, Flos Carthami 43g, Herba Lycopi 42g, Semen Plantaginis 43g, Rhizoma Atractylodis 43g, Rhizoma Alismatis 43g, Pseudobulbus Cremastrae Seu Pleiones 43g, Rhizoma Polygoni Cuspidati 42g, Herba Damnacanthi 43g, Radix Glycyrrhizae 25g and Cortex Phellodendri 44g.
Embodiment 12:
The present invention treats the Radix Clematidis ball of gout, is made up of crude drug Radix Clematidis 145g, Rhizoma Smilacis Glabrae 145g, Rhizoma Dioscoreae Hypoglaucae 145g, Semen Coicis 145g, Semen Persicae (parched) 48g, Flos Carthami 48g, Herba Lycopi 47g, Semen Plantaginis 47g, Rhizoma Atractylodis 48g, Rhizoma Alismatis 48g, Pseudobulbus Cremastrae Seu Pleiones 47g, Rhizoma Polygoni Cuspidati 47g, Herba Damnacanthi 48g, Radix Glycyrrhizae 35g and Cortex Phellodendri 48g.
Embodiment 13:
Embodiment of the present invention 1-12 treats the preparation method of the Radix Clematidis ball of gout, and its detailed step is as follows:
A, first take various crude drug according to the ratio of the Radix Clematidis ball for the treatment of gout described in embodiment 1-12 any embodiment, the various crude drug taken are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders;
B, then add the ratio of starch 26g, microcrystalline Cellulose 1.8g respectively according to every 1000g mixing fine powders, add starch, microcrystalline Cellulose mix homogeneously, the ratio adding 400g according to every 1000g mixing fine powders after mixing adds water, stirs and makes soft material after 30 minutes;
C, the soft material made by step b are placed in pellet processing machine and make the wet ball that diameter is 4.0 ~ 4.3mm;
D, that the ball that to be wet by step c gained is placed in microwave drying sterilization case is dry, dry ball moisture content≤8% of gained after dry;
E, dry for steps d gained ball is placed in coating pan bag charcoal clothing, polishing, the Radix Clematidis ball of the gout that obtains medical treatment.
Claims (4)
1. treat the Radix Clematidis ball of gout for one kind, it is characterized in that: represent with weight portion, described Radix Clematidis ball is made primarily of crude drug Radix Clematidis 130 ~ 150 parts, Rhizoma Smilacis Glabrae 130 ~ 150 parts, Rhizoma Dioscoreae Hypoglaucae 130 ~ 150 parts, Semen Coicis 130 ~ 150 parts, Semen Persicae (parched) 40 ~ 50 parts, 40 ~ 50 parts, Flos Carthami, Herba Lycopi 40 ~ 50 parts, Semen Plantaginis 40 ~ 50 parts, Rhizoma Atractylodis 40 ~ 50 parts, Rhizoma Alismatis 40 ~ 50 parts, Pseudobulbus Cremastrae Seu Pleiones 40 ~ 50 parts, Rhizoma Polygoni Cuspidati 40 ~ 50 parts, Herba Damnacanthi 40 ~ 50 parts, 20 ~ 40 parts, Radix Glycyrrhizae and Cortex Phellodendri 40 ~ 50 parts.
2. the Radix Clematidis ball for the treatment of gout according to claim 1, is characterized in that: described Radix Clematidis ball is made primarily of crude drug Radix Clematidis 135 ~ 145 parts, Rhizoma Smilacis Glabrae 135 ~ 145 parts, Rhizoma Dioscoreae Hypoglaucae 135 ~ 145 parts, Semen Coicis 135 ~ 145 parts, Semen Persicae (parched) 43 ~ 48 parts, 43 ~ 48 parts, Flos Carthami, Herba Lycopi 42 ~ 47 parts, Semen Plantaginis 43 ~ 47 parts, Rhizoma Atractylodis 43 ~ 48 parts, Rhizoma Alismatis 43 ~ 48 parts, Pseudobulbus Cremastrae Seu Pleiones 43 ~ 47 parts, Rhizoma Polygoni Cuspidati 42 ~ 47 parts, Herba Damnacanthi 43 ~ 48 parts, 25 ~ 35 parts, Radix Glycyrrhizae and Cortex Phellodendri 44 ~ 48 parts.
3. treat a preparation method for the Radix Clematidis ball of gout, it is characterized in that, described preparation method comprises the following steps:
A, first take various crude drug according to the ratio for the treatment of the Radix Clematidis ball of gout described in any one of claim 1 or 2, the various crude drug taken are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders;
B, then add the ratio of starch 23 ~ 28g, microcrystalline Cellulose 1.5 ~ 2.0g respectively according to every 1000g mixing fine powders, add starch, microcrystalline Cellulose mix homogeneously, the ratio adding 380 ~ 420g according to every 1000g mixing fine powders after mixing adds water, stirs and makes soft material after 20 ~ 30 minutes;
C, the soft material made by step b are placed in pellet processing machine and make the wet ball that diameter is 4.0 ~ 4.3mm;
D, that the ball that to be wet by step c gained is placed in microwave drying sterilization case is dry, dry ball moisture content≤8% of gained after dry;
E, dry for steps d gained ball is placed in coating pan bag charcoal clothing, polishing, the Radix Clematidis ball of the gout that obtains medical treatment.
4. treat the preparation method of the Radix Clematidis ball of gout according to claim 3, it is characterized in that: add starch 26g respectively according to every 1000g mixing fine powders in step b, the ratio of microcrystalline Cellulose 1.8g adds starch, microcrystalline Cellulose mix homogeneously; The ratio adding water 400g according to every 1000g mixing fine powders adds water.
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| CN109674960A (en) * | 2019-01-25 | 2019-04-26 | 赵廷忠 | A kind of preparation of water seedling Chinese herbal treatment gout |
| CN111068043A (en) * | 2019-12-23 | 2020-04-28 | 武汉轻工大学 | Composition rich in chicory and inulin, preparation method thereof and preparation for preventing gout |
| CN115317573A (en) * | 2022-08-18 | 2022-11-11 | 上海市第六人民医院金山分院(上海市金山区中心医院、上海市金山区中医医院) | Uric acid-reducing traditional Chinese medicine composition and application thereof in preparation of uric acid-reducing medicines |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109674960A (en) * | 2019-01-25 | 2019-04-26 | 赵廷忠 | A kind of preparation of water seedling Chinese herbal treatment gout |
| CN111068043A (en) * | 2019-12-23 | 2020-04-28 | 武汉轻工大学 | Composition rich in chicory and inulin, preparation method thereof and preparation for preventing gout |
| CN115317573A (en) * | 2022-08-18 | 2022-11-11 | 上海市第六人民医院金山分院(上海市金山区中心医院、上海市金山区中医医院) | Uric acid-reducing traditional Chinese medicine composition and application thereof in preparation of uric acid-reducing medicines |
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| CN105056020B (en) | 2018-08-10 |
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