CN101628096B - Traditional Chinese medicine composition for treating infantile diarrhea - Google Patents
Traditional Chinese medicine composition for treating infantile diarrhea Download PDFInfo
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- CN101628096B CN101628096B CN2009100175289A CN200910017528A CN101628096B CN 101628096 B CN101628096 B CN 101628096B CN 2009100175289 A CN2009100175289 A CN 2009100175289A CN 200910017528 A CN200910017528 A CN 200910017528A CN 101628096 B CN101628096 B CN 101628096B
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Abstract
The invention belongs to the technical field of the traditional Chinese medicine, which in particular relates to a traditional Chinese medicine composition for treating infantile diarrhea. The traditional Chinese medicine composition mainly comprises the following raw material medicines according to parts by weight: 30-40 parts of clove, 30-40 parts of cinnamon, 15-20 parts of evodia rutaecarpa and 5-20 parts of kaempferia galamga, and the traditional Chinese medicine composition can also comprise the following raw material medicines according to parts by weight: 1 part of radix notoginseng, 1 part of radix aconiti lateralis preparata, 6.5-10 parts of rhubarb, 0.5-1 part of borneol and 1-5 parts of white alum. The invention has the beneficial effects of obvious curative effect, quick acting, no obvious toxic or side effect, simple preparation method, no addition of other auxiliary materials, low cost and convenient use, is suitable for the external treatment of internal diseases in middle-sized and small-sized hospitals, communities and rural clinics, has favorable development prospect and social benefit and is suitable for popularization and application, and the medicine directly contacts with the skin and is absorbed by the skin.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of infantile diarrhea, belong to technical field of Chinese medicines.
Background technology
The infantile diarrhea traditional Chinese medical science claims again to have loose bowels, and is meant that children's's times of defecation increases, and excrement matter is thin, or for water sample is its feature, is one of usual diseases of childhood, and infant below two years old sees that the age is more little more, and sickness rate is high more, and clinical symptoms is heavy more.The spleen and stomach in children fragility, breast food is easily hindered, the muscles and bones weakness, wind and cold is easily attacked, congenital in addition weakness of the spleen and stomach, so being invaded by exogenous pathogen, the internal injury diet is the main cause of infantile diarrhea, so its pathological changes at taste, excessive other internal organs of then getting into bed of a specified duration.Much more primary disease all can take place throughout the year, especially to see summer and autumn and to cause popular.The medicine for the treatment of this type of disease at present clinically mostly is oral formulations, and curative effect is not satisfied.
Summary of the invention
At the particularity of pediatric pharmaceuticals, the present invention aims to provide a kind of Chinese medicine composition of treatment infantile diarrhea easy to use, evident in efficacy.
The present invention is achieved by the following technical solutions:
The Chinese medicine composition of treatment infantile diarrhea of the present invention is characterized in that comprising following raw medicaments in portion by weight: Flos Caryophylli 30-40 part, Cortex Cinnamomi 30-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 5-20 part.
The Chinese medicine composition of above-mentioned treatment infantile diarrhea, it is preferably filled a prescription is to comprise following raw medicaments in portion by weight: Flos Caryophylli 35-40 part, Cortex Cinnamomi 35-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 5-10 part; Perhaps comprise following raw medicaments in portion by weight: Flos Caryophylli 30-40 part, Cortex Cinnamomi 30-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 15-20 part.
The Chinese medicine composition of above-mentioned treatment infantile diarrhea, its preferred prescription is to comprise following raw medicaments in portion by weight: 35 parts of Flos Caryophyllis, 35 parts of Cortex Cinnamomis, 20 parts of Fructus Evodiaes, 10 parts of Rhizoma Kaempferiaes; Or comprise following raw medicaments in portion by weight: 30 parts of Flos Caryophyllis, 30 parts of Cortex Cinnamomis, 20 parts of Fructus Evodiaes, 20 parts of Rhizoma Kaempferiaes.
Above-mentioned medicine of the present invention also can comprise following raw medicaments in portion by weight: 1 part of Radix Notoginseng, and 1 part of Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei 6.5-10 part, Borneolum Syntheticum 0.5-1 part, Alumen 1-5 part, its preferred proportioning is 1 part of a Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, 6.5 parts of Radix Et Rhizoma Rhei, 0.5 part of Borneolum Syntheticum, 1 part of Alumen.
The preparation method of the Chinese medicine composition of above-mentioned treatment infantile diarrhea is: takes by weighing various crude drug by formula proportion, pulverized 120～150 mesh sieves, and mixing then, promptly.
The side separates:
Flos Caryophylli meridian distribution of property and flavor, Xin Wen return spleen, stomach kidney channel.Effect: warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG.
Cortex Cinnamomi meridian distribution of property and flavor, Xin Ganre, return kidney spleen conscience warp.Effect: mend fiery supporing yang dispersing cold for relieving pain promoting the flow of QI-blood by warming the meridian.
The Fructus Evodiae meridian distribution of property and flavor, arduous heat is slightly poisonous, returns liver taste warp.Effect: dispersing cold for relieving pain, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, dampness.
The Rhizoma Kaempferiae abnormal smells from the patient return through, hot, warm, nontoxic, return the stomach warp.Effect: warming spleen and stomach for dispelling cold, appetite-stimulating indigestion-relieving, regulating QI to relieve pain.
Radix Notoginseng meridian distribution of property and flavor, sweet little bitter temperature, return liver stomach warp.Effect: removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation.
Radix Aconiti Lateralis Preparata meridian distribution of property and flavor, very toxic, the GUIXIN kidney spleen channel of Xin Wen.Effect: recuperating depleted YANG and rescuing the patient from collapse, supporing yang, the dispersing cold for relieving pain of benefit fire.
The Radix Et Rhizoma Rhei meridian distribution of property and flavor, bitter cold is returned taste large intestine liver heart channel.Effect: heat and toxic materials clearing away, heat clearing away are thanked fire, detoxifcation, activating blood and removing stasis.
The Alumen meridian distribution of property and flavor, acid is cold, returns lung, liver, taste, large intestine.Effect: detoxifcation parasite killing dampness removing to stop itchin hemostasis antidiarrheal heat clearing away expectorant.
The Borneolum Syntheticum meridian distribution of property and flavor is worked hard and is slightly cold GUIXIN spleen lung meridian.Effect: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
One of pharmaceutical formulation of the present invention is to be Main Ingredients and Appearance with Flos Caryophylli, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Kaempferiae four flavor Chinese medicines, and all hot temperature of this four medicine has warming spleen and stomach for dispelling cold, the relieve the pain merit of antidiarrheal of spleen reinforcing the kidney warming; SHENQUE acupoint belongs to conception vessel, the moon of main the whole body, and with hands sun small intestinal, the few positive three warmers of hands, the stomach channel of foot-Yang-ming intersects, and these passages through which vital energy circulates are being dominated the ascending, descending, exiting and entering of human body, diet fortuneization, and SHENQUE acupoint is following for the through sick institute of small intestinal medicine, so can play good anti-diarrhea effect.The compositions that therefore will only contain Flos Caryophylli, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Kaempferiae is with warm water furnishing pasty state, places medically to be affixed on SHENQUE acupoint place on the umbilicus from sticking on the material night, and application time is 8～12 hours, can reach anti-diarrhea effect.Consumption is an infant below six months, each 1g, and the each 1～1.5g of six months to two years old infant, once a day.
Two of pharmaceutical formulation of the present invention is to add Radix Notoginseng, Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei, Borneolum Syntheticum, Alumen on the basis of side one.Alumen is cold and cool product, attacks long-pending detoxifcation, stasis-dispelling and pain-killing, and antidiarrheal dysentery relieving, and the hot warm-dryness syndrome of all medicines is strong more than restraining, and Radix Notoginseng removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation, Borneolum Syntheticum has the merit of transdermal, makes in medicine infiltrates through.Yongquan acupoint belongs to kidney meridian and urinary bladder channel the exterior and the interior mutually, meets at spleen at tongue, meets at pericardium at breast, and the kidney being the origin of congenital constitution, the spleen being the foundation of acquired constitution, source of generating QI and blood, three warmers master water liquid metabolism all over the body.Medicine warming middle-JIAO among this side has cold, under the invigorating middle warmer residence, and simultaneously using both cold and hot drugs, benefit is descended and is deposited, and improves gastrointestinal function, suppresses intestinal disorder, healthy energy is freely contained, evil in gushing, equally medicine is used warm water furnishing pasty state, place medical from sticking on the material, be affixed on sole Yongquan acupoint place daytime, boy is affixed on left foot first, and girl is affixed on right crus of diaphragm, can alternately stick use later on; Can cure various types of infantile diarrheas.Consumption is an infant below six months, each 1～1.5g, and the each 1.5～2g of six months to two years old infant, once a day.
If above-mentioned side one is matched with side two, be used alternatingly, then effect is better.
Compared with prior art, the present invention has following advantage: through the checking of clinical observation for many years, curative effect of medication of the present invention is remarkable, and rapid-action, medicine direct and contact skin and absorption, no obvious toxic-side effects; Preparation method is simple, does not have other adjuvants and adds, and cost is low, and is easy to use, and the inner disease outer treat of suitable small-middle hospital, community and village clinic has excellent development prospect and social benefit, is suitable for applying.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1
Get Flos Caryophylli 35g, Cortex Cinnamomi 35g, Fructus Evodiae 20g, Rhizoma Kaempferiae 10g pulverizes the back and crosses 120 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.
Get the above-mentioned medicine that makes, with warm water furnishing pasty state, place the medical center that sticks material certainly, dressing is Taizhou, Jiangsu Jingwei medical apparatus corporation, Ltd, specification 6#9; Be affixed on infant SHENQUE acupoint place night, take off after 8～12 hours.
Consumption: the each 1g of infant below 6 months; Each 1～the 1.5g of six months to two years old infant, every day 1 time.
Embodiment 2
Get Flos Caryophylli 30g, Cortex Cinnamomi 30g, Fructus Evodiae 20g, Rhizoma Kaempferiae 20g pulverizes the back and crosses 150 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.
Usage, consumption are with embodiment 1.
Embodiment 3
Get Flos Caryophylli 40g, Cortex Cinnamomi 40g, Fructus Evodiae 15g, Rhizoma Kaempferiae 5g pulverizes the back and crosses 120 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.
Usage, consumption are with embodiment 1.
Embodiment 4
Get Flos Caryophylli 38g, Cortex Cinnamomi 36g, Fructus Evodiae 18g, Rhizoma Kaempferiae 8g pulverizes the back and crosses 150 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.
Usage, consumption are with embodiment 1.
Embodiment 5
Get Flos Caryophylli 30g, Cortex Cinnamomi 30g, Fructus Evodiae 20g, Rhizoma Kaempferiae 20g, Radix Notoginseng 1g, Radix Aconiti Lateralis Preparata 1g, Radix Et Rhizoma Rhei 6.5g, Borneolum Syntheticum 0.5g, Alumen 1g pulverizes the back and crosses 120 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.Get the above-mentioned medicine that makes, with warm water furnishing pasty state, place the medical center that sticks material certainly, dressing is Taizhou, Jiangsu Jingwei medical apparatus corporation, Ltd, specification 6#9; Be affixed on infant Yongquan acupoint place daytime, take off after 8～12 hours, boy is affixed on left foot first, and girl is affixed on right crus of diaphragm first, can alternately stick use later on.
Consumption is an infant below six months, each 1～1.5g, the each 1.5～2g of six months to two years old infant, every day 1 time.
Embodiment 6
Get Flos Caryophylli 30g, Cortex Cinnamomi 30g, Fructus Evodiae 20g, Rhizoma Kaempferiae 20g, Radix Notoginseng 1g, Radix Aconiti Lateralis Preparata 1g, Radix Et Rhizoma Rhei 8g, Borneolum Syntheticum 0.8g, Alumen 2g pulverizes the back and crosses 150 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.Get the above-mentioned medicine that makes, with warm water furnishing pasty state, place the medical center that sticks material certainly, dressing is Taizhou, Jiangsu Jingwei medical apparatus corporation, Ltd, specification 6#9; Be affixed on infant Yongquan acupoint place daytime, take off after 8～12 hours, boy is affixed on left foot first, and girl is affixed on right crus of diaphragm first, can alternately stick use later on.
Consumption is with embodiment 5.
Embodiment 7
Get Flos Caryophylli 36g, Cortex Cinnamomi 36g, Fructus Evodiae 15g, Rhizoma Kaempferiae 5g, Radix Notoginseng 1g, Radix Aconiti Lateralis Preparata 1g, Radix Et Rhizoma Rhei 10g, Borneolum Syntheticum 0.6g, Alumen 5g pulverizes the back and crosses 150 mesh sieves, and mix homogeneously is bottled then, promptly makes Chinese medicine composition of the present invention.Get the above-mentioned medicine that makes, with warm water furnishing pasty state, place the medical center that sticks material certainly, dressing is Taizhou, Jiangsu Jingwei medical apparatus corporation, Ltd, specification 6#9; Be affixed on infant Yongquan acupoint place daytime, take off after 8～12 hours, boy is affixed on left foot first, and girl is affixed on right crus of diaphragm first, can alternately stick use later on.
Consumption is with embodiment 5.
Embodiment 8
Get Flos Caryophylli 35g, Cortex Cinnamomi 35g, Fructus Evodiae 20g, Rhizoma Kaempferiae 10g pulverized 120 mesh sieves, and mix homogeneously is made the A medicine then, and it is standby to bottle; Get Flos Caryophylli 30g, Cortex Cinnamomi 30g, Fructus Evodiae 20g, Rhizoma Kaempferiae 20g, Radix Notoginseng 1g, Radix Aconiti Lateralis Preparata 1g, Radix Et Rhizoma Rhei 6.5g, Borneolum Syntheticum 0.5g, Alumen 1g pulverizes the back and crosses 120 mesh sieves, and mix homogeneously is made the B medicine then, and it is standby to bottle.Get the medicinal warm water furnishing of A pasty state, place medical from the center that sticks material, be affixed on SHENQUE acupoint place on the umbilicus night, take off after 8～12 hours, get the medicinal warm water furnishing of B pasty state again, place medical from the center that sticks material, be affixed on infant Yongquan acupoint place daytime, boy is affixed on left foot first, and girl is affixed on right crus of diaphragm first, can alternately stick use later on, take off after same 8～12 hours.Two medicines are used alternatingly.
Consumption: infant consumption below 6 months is the each 1g of A medicine, the each 1～1.5g of B medicine, and the infant consumption to two years old more than 6 months is the each 1～1.5g of A medicine, the each 1.5～2g of B medicine, is every day 1 time.
Clinical observation on the therapeutic effect
Chinese medicine composition of the present invention is carried out clinical experiment observe, the result is as follows:
(1) clinical case: from 1993-2008,1 month various diarrhoea infant 1800 example of reception treatment, boy baby 1119 people wherein, girl baby 681 people to two one full year of life.
Diagnostic criteria was according to State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " 1994.
A infant stool is increased, and day reaches 3～5 times, and is very more.
B suffers from diarrhoea, and just color is yellowish, is rare water or egg soup sample.
All infants of c all with nausea and vomiting and in various degree the dehydration and electrolyte disturbance.Microscopy is not found pyocyte, blood cell and mycete, and stool is cultivated negative.
(2) Therapeutic Method:
The patient is divided into 3 groups at random, group 1:400 people, the medicine of use embodiment 1; Group 2:400 people, the medicine of use embodiment 5; Group 3:1000 people uses the medicine of embodiment 8 to treat.
Usage and consumption: the thing of getting it filled respectively, with warm water furnishing pasty state, place the medical center that sticks material certainly, dressing is Taizhou, Jiangsu Jingwei medical apparatus corporation, Ltd, specification 6#9.
Group 1 infant in night with plaster SHENQUE acupoint place on umbilicus, take off after 8～12 hours; The each 1g of infant below 6 months; Each 1～the 1.5g of six months to two years old infant, every day 1 time.
The infant of group 2 is affixed on sole Yongquan acupoint place daytime with medicine, takes off after 8～12 hours, and boy is affixed on left foot first, and girl is affixed on right crus of diaphragm first, can alternately stick use later on; Consumption is the each 1～1.5g of infant below six months, the each 1.5～2g of six months to two years old infant, every day 1 time.
Group 3 infant in night with A plaster SHENQUE acupoint place on umbilicus, daytime, in sole Yongquan acupoint place, boy was affixed on left foot first with the B plaster, girl is affixed on right crus of diaphragm, can alternately stick use later on; A, B medicine are used alternatingly, and application time is 8～12 hours.The consumption of infant below 6 months is the each 1g of A medicine, the each 1～1.5g of B medicine, and the infant consumption to two years old more than 6 months is the each 1～1.5g of A medicine, the each 1.5～2g of B medicine, is every day 1 time.
(3) therapeutic evaluation standard:
A cures: times of defecation, character and symptom, sign are recovered normally fully, and unusual physics and chemistry also recovers normal.
The B produce effects: times of defecation obviously reduces (reducing to 1/3 before treating or following), and character takes a turn for the better, and symptom, sign and unusual physical and chemical index obviously improve.
C is invalid: do not meet above standard person.
(4) therapeutic effect:
| Group | Cure number | The produce effects number | Invalid number | The shortest healing time | Heal the time in Changzhi | Average cure time |
| Group 1 | 324 examples | 50 examples | 26 examples | 4 days | 6 days | 5 days |
| Group 2 | 326 examples | 52 examples | 22 examples | 4 days | 7 days | 5 days |
| Group 3 | 915 examples | 49 examples | 36 examples | 2 days | 5 days | 3 days |
Model case
Case one
8 months addresses of Ma man: Zhen Maqiao village, the Licheng District Huashan, Jinan City
The bimester of infant diarrhoea, day row 10-20 time is green egg style water just; When exerting oneself, the urine aerofluxus all can discharge stool.Because of its father and mother make business outside, successively in Qingdao, stone island transfusion, paste medicine, take medicine, nearly 2 monthly not the feeling any better of massage treatment, with the household get in touch clarify the state of an illness after, prescription by embodiment 8 makes up a prescription, deliver to Qingdao, stop other treatment, sticked this medicine 5 days and heal.
Case two
7 months addresses of Lee man: beachhead village, Licheng District king rounding off town, Jinan City
Infant diarrhoea 4 months, outbreak repeatedly, a day row does not wait for 5-10 time, and it just is the yellow green watery stool, and the blood filament is arranged sometimes, and is once repeatedly invalid in the provincial, and municipal level hospitalize, treats to this institute, makes up a prescription by the prescription of embodiment 4, sticks this medicine 5 days and heals.
Case three
Ma, woman 1 years old in the Jinan, address one, was rushed down following 3 days, day row 8-10 time, the egg style is just taken medicine, and it is invalid to infuse in hospital, treats to this institute, makes up a prescription by the prescription of embodiment 4, sticks this medicine 5 days and heals.
Claims (5)
1. a Chinese medicine composition for the treatment of infantile diarrhea is characterized in that the weight portion of crude drug is: Flos Caryophylli 30-40 part, Cortex Cinnamomi 30-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 5-20 part, 1 part of Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei 6.5-10 part, Borneolum Syntheticum 0.5-1 part, Alumen 1-5 part.
2. the Chinese medicine composition of treatment infantile diarrhea according to claim 1 is characterized in that the weight portion of crude drug is: Flos Caryophylli 35-40 part, Cortex Cinnamomi 35-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 5-10 part, 1 part of Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei 6.5-10 part, Borneolum Syntheticum 0.5-1 part, Alumen 1-5 part.
3. the Chinese medicine composition of treatment infantile diarrhea according to claim 1 is characterized in that the weight portion of crude drug is: Flos Caryophylli 30-40 part, Cortex Cinnamomi 30-40 part, Fructus Evodiae 15-20 part, Rhizoma Kaempferiae 15-20 part, 1 part of Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei 6.5-10 part, Borneolum Syntheticum 0.5-1 part, Alumen 1-5 part.
4. the Chinese medicine composition of treatment infantile diarrhea according to claim 2 is characterized in that the weight portion of crude drug is: 35 parts of Flos Caryophyllis, 35 parts of Cortex Cinnamomis, 20 parts of Fructus Evodiaes, 10 parts of Rhizoma Kaempferiaes, 1 part of Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei 6.5-10 part, Borneolum Syntheticum 0.5-1 part, Alumen 1-5 part.
5. the Chinese medicine composition of treatment infantile diarrhea according to claim 3 is characterized in that the weight portion of crude drug is: 30 parts of Flos Caryophyllis, 30 parts of Cortex Cinnamomis, 20 parts of Fructus Evodiaes, 20 parts of Rhizoma Kaempferiaes, 1 part of Radix Notoginseng, 1 part of Radix Aconiti Lateralis Preparata, 6.5 parts of Radix Et Rhizoma Rhei, 0.5 part of Borneolum Syntheticum, 1 part of Alumen.
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| CN2009100175289A CN101628096B (en) | 2009-08-04 | 2009-08-04 | Traditional Chinese medicine composition for treating infantile diarrhea |
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| CN2009100175289A CN101628096B (en) | 2009-08-04 | 2009-08-04 | Traditional Chinese medicine composition for treating infantile diarrhea |
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| CN101628096B true CN101628096B (en) | 2011-06-08 |
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| CN102526297A (en) * | 2012-01-19 | 2012-07-04 | 中山大学 | Chinese medicine gel ointment for treating children diarrhea and preparing method thereof |
| CN104435958A (en) * | 2014-11-20 | 2015-03-25 | 山东瑞康生命科技有限公司 | Traditional Chinese medicine preparation for treating fulminant dysentery and preparation method thereof |
| CN104758317A (en) * | 2015-05-04 | 2015-07-08 | 李汶峰 | Producing method of fever abatement febrifuge |
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Granted publication date: 20110608 Termination date: 20210804 |