CN104971214B - A kind of Chinese medicine composition with antifatigue effect - Google Patents
A kind of Chinese medicine composition with antifatigue effect Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition with antifatigue effect.The present inventor is by clinical practice for many years,, deficiency of vital energy cough with asthma, lose blood impairment caused by overstrain prosperous for fatiguability crowd such as lung-fire produced by during one's sickness, forgetful insomnia, calentura wound rule, soreness of waist and knee joint, blurred vision such as fail to understand at the symptom, invent a kind of Chinese medicine composition with significant curative effect, above-mentioned symptom can be made to obtain curing and effectively alleviating.The Chinese medicine composition of wherein said resisting fatigue is made up of the following raw materials according of following weight portion: Radix Panacis Quinquefolii 3 15 grams, Radix Ophiopogonis 6 12 grams, Fructus Schisandrae Chinensis 2 15 grams, Fructus Lycii 6 15 grams, the Radix Astragali 9 30 grams, Flos Chrysanthemi 5 15 grams.Described compositions constitutes simple, reasonable mixture ratio, and without any side effects, and curative effect is fixed, and the repeatability of medical effect is high, has the highest safety and effectiveness.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine composition with resisting fatigue.
Background technology
Tired conventional " tiring out " represents, in general everybody had this experience.Physical activity, to time time certain, is organized
Organ or even the whole temporarily-depressed phenomenon of body ability to work are tired.The tired physical fatigue being divided into again somatotonia to be master
It is main mental fatigue with psychentonia.No matter physical fatigue or mental fatigue, is all corticocerebral protective effect.Interior environment
Change promotes the protectiveness suppression of brain, and fatigue represents the reduction of central nervous system's ability to work.When musculation arrives
Time to a certain degree, energy substance is exhausted;The factor such as metabolite accumulation, homeostasis imbalance in blood, is all tired generation
Reason.As can be seen here, fatigue is the reaction that internal and external environment is adapted to be made by life entity, is also a kind of physiological defense reaction.
From this meaning, pay attention to that tired understanding and the allaying tiredness that takes measures are had considerable meaning.Tired symptom
Generally comprise following three aspects: one is to feel aspect: as tired in omnidirectional, nose heave, drowsiness, unable etc.;Two is spirit side
Face: as distraction, lather, do not have patience, depressed, without earnest, often make mistakes;Three is whole body aspect: face
Color is pale, dizziness, muscle twitches dyspnea, dry mouth and parching tongue, hoarseness, soreness of waist and ache in legs etc..
The factor causing fatigue mainly have zinc deficiency, do not have enough sleep, lack exercise, vivotoxin accumulation, fat, spiritual because of
Element, pressure are big and endocrine disturbance, medicine factor, acidic physique etc. are all the principal elements causing fatigue.One relates to complete
The sub-health status Epidemiological study of 10 provinces and regions 11980 people of state shows, the non-diseased crowd of 81.36% belongs to confirmed fatigue.
Wherein, often feel like fatigue, but the slight fatigue person that can recover after having a rest accounts for 68.07%;Always feel tired, and after rest relatively
The difficult moderate fatigue person recovered accounts for 29.78%;Also the severe fatigue person that cannot recover after rest accounts for 2.15%.Human body has compensatory machine
System, tired sleeping can youngster just can adjust more once in a while, if but chronic fatigue, may result in Abwehrkraft des Koepers and decline, after rest
Also cannot recover.Tired constantly accumulation once in a while, it is possible to develop into confirmed fatigue, infringement health.And the harm master of fatigue
Including: to the harm in terms of human body physical agility, figure, show that being difficult to be engaged in or complete some consumes one's strength compared with big and action is thin
Greasy, exquisite work, causes patient to feel unable to do what one wishes deeply；Harm to human immune system, can make the immune system merit of human body
Can be not normal with regulation, cause immunologic hypofunction, cause various disease；To human recycle system, nervous system, digestive system,
Reproductive system and the harm of sensorium.Modern Chinese medicine is thought, fatigue is a name of disease, has its etiology and pathogenesis, is clinically
Commonly encountered diseases, frequently-occurring disease, be the new sick kind that must pay attention to, be attributed to subhealth state category, relate to the vital organs of the human body, with spleen, liver, kidney be mainly
Main.Can be recuperated under medical treatment by Chinese medical discrimination prescription, to reach the purpose prevented, treat, control.Fatigue be unit QI consumed wound deficiency syndrome and
Caused by mental change (or the most smooth) double factor.Qi-restoratives righting is not only wanted, tired calming the nerves of also should dispelling in treatment.On the one hand, qi-restoratives is solid
Unit, nourishes body, empty must mend, and canonical is prosperous, tired from removing;On the other hand, adjust smooth will, comfortable smooth meaning, refreshing must pacify, the heart is then peaceful,
Fatigue can disappear.Fatigue is described as " slacking off ", " slack lazy ", " extremity overstrain ", " inability to raise the limbs " and " flaccidity of the limbs " by Chinese medical book
Deng.As " Plain Questions shows calm opinion " is said: " flaccidity of the limbs, this inability of the spleen to transport the essence of food is also.", " Shengji Zonglu asthenia door " say: " impairment caused by overstrain
Very, the tired pole of health.", " east permanent ten book inability to bend the limbs " say: " taste void then tiredness with somnolence, inability to bend the limbs.", Qing Dynasty woods wears
Qin " the deficient piece of Lei Zheng Zhi Cai " once pointed out that asthenia had five, and impairment of the lung caused by overstrain damages gas, and the impairment of the spleen due to overstrain damages food, and the impairment of the heart caused by overstrain damages god, and hepatic asthenia damages blood, and impairment of the kidney caused by overstrain damages
Essence.Melancholia then summarises the symptom in terms of confirmed fatigue comprehensively demonstrate,proves a series of spirit occurred, and to hypomnesis or
Absent minded, pharyngolaryngitis, cervical region or axillary gland tenderness, myalgia, multiple non-arthritic joint pain, headache,
Sleep disorder etc., its clinical manifestation has intersection to be present in the diseases such as " forgetful ", " pharyngalgia ", " arthralgia ", " headache ", " being insomnia "
In record.If human body's Qi generation pathological changes, mind activity will be produced impact.Say that such as " Ling Shu Miraculous Pivot or Divine Axis is the most puzzled " " upper gas is not
Foot, the therapeutic method to keep the adverse QI flowing downwards has a surplus, and the intestines and stomach is real and cardiopulmonary are empty, void then seek defend stay under, for a long time not with time on.”
The method of western medical treatment fatigue includes medicine, immunotherapy, antiviral therapy, cognition and the behavior therapy and reason
Treat, all at relief of symptoms, improve function, but still lack effective therapeutic regimen that recommend, definite.And the traditional Chinese medical science should in diagnosis and treatment
It is divided into type of deficiency of both the heart and spleen, the deficiency of vital energy to hold the symptoms such as strongly fragrant type, deficiency of both the liver and kidney type and caused by hepatic stagnation qi stagnation under the arm this disease during sick existing symptom,
Need to treat the most to the ill.And this Chinese medicine composition of the present inventor's invention is valued in the gasification function of energy integrated regulation internal organs,
The most positive benefiting vital QI and blood, is affirmative in health invigorating, resisting fatigue, the effect of antidotal therapy fatigue, according to fatigue disease
Because of pathogenic characteristic, select multiple sides such as strengthening vital QI to eliminate pathogenic factors, supplementing QI and nourishing YIN, the clots absorbing that reduces phlegm, regulating the flow of QI to alleviate depression, heat-clearing and toxic substances removing, harmonizing yingfen and weifen
The square medicine in face, by determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, Yin Yang balancing, QI and blood regulating, conditioning viscera, can reverse its pathomechanism, prevent complication
Generation, achieve preferable curative effect, from the entirety of people reach recover the normal function of body.
Summary of the invention
The present inventor is engaged in Chinese medicine from generation to generation and works for many years, have accumulated abundant Clinical Laboratory and case, by this
The analysis of disease, study and confirm, having invented the formula that this group is new, for physical fatigue crowd because tired produced one
Serious complications and harm have significant curative effect, and this disease can be made effectively to be alleviated and treatment.
Therefore.In the first aspect of the invention, it is provided that a kind of Chinese medicine composition treating resisting fatigue, it is by following weight
The following raw materials according of part is made, unit g:
Radix Panacis Quinquefolii 3-15, Radix Ophiopogonis 6-12, Fructus Schisandrae Chinensis 2-15, Fructus Lycii 6-15, Flos Chrysanthemi 5-15, Radix Astragali 9-30.
In preferred embodiments, described Chinese medicine composition by Radix Panacis Quinquefolii 3-10, Radix Ophiopogonis 6-10, Fructus Schisandrae Chinensis 2-10, Chinese holly
Fructus Lycii 6-10, Flos Chrysanthemi 5-10, Radix Astragali 9-25 make.
The preparation method of this Chinese medicine composition is:
By raw material Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Radix Astragali is respectively put into decocts medicinal herbs with in marmite, adds proper amount of clear water and soaks, and the water yield was not to have
Medical material is advisable, and after soaking 10-20 minute, is first fried boiling with intense fire, fried 10-15 minute, then decocts 15-20 minute with slow fire,
Radix Panacis Quinquefolii, Fructus Lycii, Flos Chrysanthemi are put into frying pan the most fried 5-10 minute in before fried end 3-5 minute, filter medicinal liquid, place temperature
Heat time the most drinkable.Or above-mentioned raw materials is crushed to respectively 80～120 mesh, through sieving, sterilizing, is dried, mixing, the life of extraction
Production. art makes capsule, tablet or oral liquid.
Radix Panacis Quinquefolii in this Chinese medicine composition is the dry root of Araliaceae Radix Panacis Quinquefolii, has lung benefiting cloudy, and clear asthenic fire is raw
The effect quenched the thirst in Tianjin, archaism cloud: " Radix Panacis Quinquefolii is cool in nature and mends, all Radix Ginsengs to be used and all can be with it by the temperature person of Radix Ginseng ".Therefore mend
And the driest be the special feature of Radix Panacis Quinquefolii.Radix Panacis Quinquefolii rhizome contains glycoside, mainly ginsenoside.There are some researches show, Radix Panacis Quinquefolii exists
Resisting fatigue aspect has obvious effect, and Radix Panacis Quinquefolii can promote protein synthesis, regulates metabolism, rapid relieving fatigue,
Regain one's strength.Radix Panacis Quinquefolii can improve anoxia enduring and the tolerance to cold of white mice, it is possible to is obviously prolonged the mice burden swimming time,
Serum urea nitrogen level when reducing motion, reduces the consumption of liver glycogen, reduces the content of high dose group lactic acid after moving.The West
Ginseng saponin can promote that protein generates a-acetone acid through deamination reaction after being broken down into aminoacid again, and the latter joins as intermediate product
Add tricarboxylic acid cycle, carry out oxidative function, thus reach the purpose of resisting fatigue.Fructus Schisandrae Chinensis has QI invigorating reinforcing YIN-essence, improving eyesight, strong muscle
The effects such as bone, foster the five internal organs.Functional component Fructus Schisandrae Polysaccharide in Fructus Schisandrae Chinensis can significantly improve mice oxygen deficit tolerance ability, can show
Write the walking weight load extending mice, there is increase muscle power and antifatigue effect.Fructus Schisandrae Polysaccharide presses 100mg/kg, 200mg/
Mice, to mouse stomach, is put in the airtight wide mouthed bottle of the 250ml equipped with 10g Calx by kg dosage, and experiment shows, Fructus Schisandrae Polysaccharide
The hypoxia-bearing capability of mice can be significantly improved, point out it to have antifatigue effect.There is Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, merit that lung moistening clears away heart-fire
Can, can be used for the calentura wound disease such as rule, restlessness and thirst, its main chemical compositions is homoisoflavone class, soaping agents, volatile oil, inorganic
Element and polysaccharide etc..Radix Ophiopogonis polysaccharide is one of main active in Radix Ophiopogonis, occupy blood sugar lowering, slow down aging, resisting fatigue, auxiliary
Help the suppression effect such as tumor, radioprotective.The Radix Astragali has the effects such as tonifying Qi and lifting yang, stomach reinforcing consolidating superficial resistance, inducing diuresis to remove edema, detoxification granulation promoting, is
The tonic that China is traditional.Modern pharmacological research shows, the Radix Astragali has resisting fatigue, defying age, regulation immunologic function, removing toxic substances etc. and makees
With, the Radix Astragali is containing multiple chemical compositions such as saponin, pyrite, polysaccharide and aminoacid, and wherein polysaccharide is Radix Astragali primary bioactive components,
Astragalus polysaccharides can reduce the accumulation of body blood lactic acid, enhancing body aerobic capacity, plays delay fatigue and occurs, improves motion
The effect of ability.Fructus Lycii have nourishing the liver and kidney, replenishing vital essence to improve eyesight, nourish blood, the effect such as enhancing immunity.Research display, Fructus Lycii is the most real
Effect be exactly resisting fatigue and blood pressure lowering.There is experiment to show, use water extraction that Fructus Lycii is extracted, use mice swimming with a load attached to the body
Swimming method, pole-climbing chronometry and Mouse Liver heavily claim method that the anti-fatigue active of Fructus Lycii variable concentrations extract is compared research,
Fructus Lycii has the effect of significant resisting fatigue, it is possible to by increasing the deposit of hepatic glycogen, provides more energy to reach for body
Purpose to resisting fatigue.
The Chinese medicine composition of the present invention has the effect of resisting fatigue, can effectively prevent and treatment answers that QI and blood is not normal, internal organs
The fatigue symptom that functional disorder, feelings will do not relaxes, overwork etc. and occurs.This Chinese medicine composition uses the traditional Chinese medical science to pharmacology opinion, group
Square tube overregulates that negative and positive, QI and blood regulating, temperature are cool and to mend vital essence with, settling five organs be main, with reach Yin-nourishing and Yang-supporting, train consolidate, spleen
Kidney is taken into account, effect of invigorating the spleen and replenishing QI.
The Chinese medicine composition of the present invention constitutes simple and practical, reasonable mixture ratio, it is possible to nourishing the blood and yin, calm the nerves, vital essence replenishing and marrow benifiting, tune
With negative and positive, the spleen and stomach regulating, for during fatigue occur insufficiency of the spleen, suffer from a deficiency of the kidney, excess of the liver, soreness of the waist and knees, dizziness and tinnitus, Shou Zuxin
The symptoms such as stagnation of liver-QI with deficiency of the spleen, deficiency of the kidney yin such as heat, neurolysis, irritable, can significantly be treated and be alleviated.In the present invention
Drug composition is through 170 example patient fatigue's clinical research confirmations, total effective rate 98, cure rate 95.No matter age size, medical history
Length, all can have significant curative effect, and determined curative effect within a course for the treatment of, and the repeatability of medical effect is high, has no side effect, through clinic
Checking cure rate is higher.
Detailed description of the invention
Embodiment 1
Radix Panacis Quinquefolii 3-15 gram, Radix Ophiopogonis 6-12 gram, Fructus Schisandrae Chinensis 2-15 gram, Fructus Lycii 6-12 gram, Radix Astragali 9-30 gram, Flos Chrysanthemi 5-15
Restrain into.
Preparation method: by raw material Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Radix Astragali is respectively put into decocts medicinal herbs with in marmite, adds proper amount of clear water and soaks, the water yield with
Do not had medical material to be advisable, and soaked about 10-20 minute, afterwards, be first fried boiling with intense fire, fried 10-15 minute, then decoct 15-with slow fire
20 minutes, within 3-5 minute before fried end, Radix Panacis Quinquefolii, Fructus Lycii, Flos Chrysanthemi are put into frying pan the most fried 5-10 minute, filters medicine
Liquid, places during warm the most drinkable.Or carry out respectively being crushed to 80～120 mesh, through sieving, sterilizing by above-mentioned raw materials, it is dried, mixed
Closing, the production technology such as extraction is fabricated to capsule, tablet, oral liquid, extends the storage phase, and mouthfeel is improved, and purity has
Bigger raising, and applicable industrialized production.Three times a day, take after half an hour after meal.
Embodiment 2
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-10 gram, Radix Ophiopogonis 6-10 gram, Fructus Schisandrae Chinensis 2-10 gram, Fructus Lycii 6-15 gram, Radix Astragali 9-20 gram, Flos Chrysanthemi 2-12
Gram.
Preparation and using method: with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-12 gram, Radix Ophiopogonis 6-10 gram, Fructus Schisandrae Chinensis 2-12 gram, 6-10 gram of Radix Astragali of Fructus Lycii 9-25 gram, Flos Chrysanthemi 5-10
Gram.
Preparation and using method: with embodiment 1.
Embodiment 4
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-10 gram, Radix Ophiopogonis 6-12 gram, Fructus Schisandrae Chinensis 2-15 gram, Fructus Lycii 6-10 gram, Radix Astragali 9-18 gram, Flos Chrysanthemi 5-15
Gram.
Preparation and using method: with embodiment 1.
Embodiment 5
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-15 gram, Radix Ophiopogonis 6-12 gram, Fructus Schisandrae Chinensis 2-10 gram, Fructus Lycii 6-15 gram, Radix Astragali 9-20 gram, Flos Chrysanthemi 5-10
Gram.
Preparation and using method: with embodiment 1.
Embodiment 6
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-15 gram, Radix Ophiopogonis 6-12 gram, Fructus Schisandrae Chinensis 2-15 gram, Fructus Lycii 6-12 gram, Radix Astragali 9-25 gram, Flos Chrysanthemi 5-12
Gram.
Preparation and using method: with embodiment 1.
Embodiment 7
A kind of Chinese medicine composition with resisting fatigue, it forms by by the raw material of following weight:
Radix Panacis Quinquefolii 3-12 gram, Radix Ophiopogonis 6-10 gram, Fructus Schisandrae Chinensis 2-12 gram, Fructus Lycii 6-15 gram, Radix Astragali 9-20 gram, Flos Chrysanthemi 5-15
Gram.
Preparation and using method: with embodiment 1.
Embodiment 8: experimental example
Diagnostic criteria is with reference to the diagnostic criteria of U.S. CDC revision: 1. lasting the or recurrent exerbation of unknown cause is the most tired
Labor, continues more than six months, and after fully having a rest, symptom is not alleviated, and declines 50,2. at least have simultaneously when level of activation is more healthy
In standby following eight four: short-term attentional power or memory are decreased obviously, pharyngalgia, and cervical region or axillary gland swell and ache, muscle
Pain, without red and swollen arthralgia, the headache that novel or degree increases the weight of, the sleep do not recovered from fatigue, Fatique after Sports was more than 24 hours.
Choose 170 examples meeting above-mentioned standard, regardless of sex, the age 20～60 years old, the course of disease 2 months～2 years.
Therapeutic scheme
Treatment group: use the Chinese medicine composition in embodiment 1, take 3 every day.
Criterion of therapeutical effect
Clinical symptoms is by light middle weight grading, and fatigue is indispensable disease, uses Fatigue Assessment Instument to evaluate, will be in tired
The relevant performance of labor is listed one by one, point 1～7 grade of evaluation.
Efficacy evaluation is: effective: clinical symptom disappearance or be obviously improved, and symptom integral reduces more than 2/3, takes a turn for the better: clinical
Symptom alleviates, and symptom integral reduces more than 1/3, and invalid: clinical symptoms is without improvement or increases the weight of, integration reduces less than 1/3.
Therapeutic outcome
According to symptom scores standard, effective 160 examples of patient treatment group, effective 7 examples, total effective rate 98, and do not send out
Raw any untoward reaction.
The Chinese medicine composition thus demonstrating the present invention has good effectiveness and reliability.
Claims (4)
1. having a Chinese medicine composition for antifatigue effect, it is made up of the raw material of following weight portion: Radix Panacis Quinquefolii 3-15 gram, wheat
Winter 6-12 gram, Fructus Schisandrae Chinensis 2-15 gram, Radix Astragali 9-30 gram, Fructus Lycii 6-15 gram, Flos Chrysanthemi 5-15 gram, by raw material Radix Ophiopogonis, Fructus Schisandrae Chinensis, yellow
Stilbene is respectively put into decocts medicinal herbs with in marmite, adds proper amount of clear water and soaks, and the water yield was not there to be medical material to be advisable, after soaking 10-20 minute, first
Be fried boiling with intense fire, fried 10-15 minute, then decoct 15-20 minute with slow fire, before fried end 3-5 minute by Radix Panacis Quinquefolii, Chinese holly
Qi, Flos Chrysanthemi put into frying pan the most fried 5-10 minute, filter medicinal liquid, place during warm the most drinkable.
A kind of Chinese medicine composition with antifatigue effect the most according to claim 1, it is made up of the raw material of following weight portion:
Radix Panacis Quinquefolii 3-10 gram, Radix Ophiopogonis 6-10 gram, Fructus Schisandrae Chinensis 2-10 gram, Fructus Lycii 6-10 gram, Radix Astragali 9-25 gram, Flos Chrysanthemi 5-10 gram.
3. the preparation method of the Chinese medicine composition described in claim 1 or 2, it is characterised in that:
By raw material Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Radix Astragali is respectively put into decocts medicinal herbs with in marmite, adds proper amount of clear water and soaks, and the water yield was not there to be medical material
It is advisable, after soaking 10-20 minute, is first fried boiling with intense fire, fried 10-15 minute, then decoct 15-20 minute with slow fire, fried
Radix Panacis Quinquefolii, Fructus Lycii, Flos Chrysanthemi were put into frying pan the most fried 5-10 minute in 3-5 minute before Jie Shuing, filter medicinal liquid, when placing warm
The most drinkable.
4. having a Chinese medicine composition for antifatigue effect, it is made up of the raw material of following weight portion: Radix Panacis Quinquefolii 3-10 gram, wheat
Winter 6-10 gram, Fructus Schisandrae Chinensis 2-10 gram, Fructus Lycii 6-10 gram, Radix Astragali 9-25 gram, Flos Chrysanthemi 5-10 gram,
Above-mentioned raw materials is crushed to respectively 80～120 mesh, through sieving, sterilizing, be dried, mix, the production technology extracted makes glue
Capsule, tablet or oral liquid.
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| CN1426787A (en) * | 2001-12-20 | 2003-07-02 | 肖永良 | Health care mixture for antifatigne and enhancing immunity |
| CN101019645A (en) * | 2007-03-08 | 2007-08-22 | 肖樾 | Health food for remitting fatigue and raising hypoxia tolerance and its prepn |
| CN103656198A (en) * | 2013-12-17 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Anti-fatigue traditional Chinese medicine combination |
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