CN107714836A - A kind of traditional Chinese herbal decoction of cure hiccup and preparation method thereof - Google Patents

A kind of traditional Chinese herbal decoction of cure hiccup and preparation method thereof Download PDF

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CN107714836A
CN107714836A CN201711156456.7A CN201711156456A CN107714836A CN 107714836 A CN107714836 A CN 107714836A CN 201711156456 A CN201711156456 A CN 201711156456A CN 107714836 A CN107714836 A CN 107714836A
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傅俊杰
傅星淏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/44Ebenaceae (Ebony family), e.g. persimmon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
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    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of traditional Chinese herbal decoction of cure hiccup, it is prepared by the raw material of following parts by weight:12 18 parts of cloves, 12 18 parts of agalloch eaglewood, 10 14 parts of dried orange peel, 10 14 parts of rascal, 12 18 parts of the calyx and receptacle of a persimmon, 10 14 parts of radix bupleuri.Preparation method comprises the following steps:(1)The raw material configured is put into 40 DEG C of water and soaked 50 minutes, feed liquid mass ratio is 1:6;(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3 minutes and is boiled 35 minutes, completes to filter out decoction after decocting first;(3)Water is added again, and feed liquid mass ratio is 1:2, intense fire is changed to slow fire and boiled 30 minutes after being heated to boiling, filters out decoction after completing secondary decoction;(4)The decoction filtered out in above-mentioned steps is mixed to prepare to the traditional Chinese herbal decoction of cure hiccup.This traditional Chinese herbal decoction has inverse pleasant drop, resolving sputum preventing or arresting vomiting, relax liver and stomach and other effects, has good therapeutic effect to hiccup.

Description

A kind of traditional Chinese herbal decoction of cure hiccup and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of traditional Chinese herbal decoction of cure hiccup and preparation method thereof.
Background technology
Hiccup, be commonly called as " having the hiccups ", be contractile motion caused by diaphragmatic spasm, during air-breathing glottis close suddenly send it is a kind of short The sound of rush.The diaphram in unilateral or bilateral can be sent out.Hiccup is a kind of clinical common symptom, with diet, mental element relation Closely, a variety of diseases such as digestive system, nervous system, respiratory system are also common in and cause stimulation vagus nerve or nervus phrenicus institute Cause.The lighter can voluntarily be alleviated, and typically be not required to specific drugs treatment.Severe one turns into " intractable hiccup ", and general persistence is longer, Even cause the secondary arthritis performance such as anorexia, gastral cavilty and belly turgor, pain.
The traditional Chinese medical science thinks that hiccup is pented up mainly due to cold-evil, Sheng, the resistance of obstruction of the circulation of vital energy phlegm and deficiency of qi and blood etc. cause in stomach Qi in stomach fire Inverse and cause, the cause of disease of hiccup is mainly eating and drinking without temperance, the thing of eating cold and uncooked food excessively or cold and cool medicine, causes cold air to pent up in stomach, stomach Qi Lose in drop and superinverse;Or feelings will discord, depressed angry, stagnation of QI due to depression of the liver, perverse and unreasonable manner violate stomach, so that stomach Qi rising;Or because of the obstruction of the circulation of vital energy Fire, fluid transformed into phlegm by fire, stomach Qi are held phlegm superinverse under the arm and formed;Or because the agent told down of disease misuse damages stomach Tianjin, stomach lose it is foster in moistening so that in stomach Qi It is inverse.Hiccup is all caused by stomach Qi upward reversal, treatment when with stomach sending down abnormally ascending only oh based on.
At present, modern medicine is clinically directed to hiccup symptom, also without suitable method, can only use metoclopramide, profit he The medicines such as woods, domperidone (Domperidone), which are suited the medicine to the illness, is treated, and often has that therapeutic effect is poor, course for the treatment of length, medical expense height etc. Problem.
The content of the invention
The purpose of the present invention be that for solve the deficiencies in the prior art provide a kind of cure hiccup traditional Chinese herbal decoction and Its preparation method.Its traditional Chinese herbal decoction is high to the treatment specific aim of hiccup, and therapeutic effect is good, short treating period, and it is low to prepare cost.
The purpose of the present invention with following technical proposals by being realized:
A kind of traditional Chinese herbal decoction of cure hiccup, is prepared by the raw material of following parts by weight:Cloves 12-18 parts, agalloch eaglewood 12-18 Part, dried orange peel 10-14 parts, rascal 10-14 parts, calyx and receptacle of a persimmon 12-18 parts, radix bupleuri 10-14 parts.
Preferably, the traditional Chinese herbal decoction of cure hiccup, it is prepared by the raw material of following parts by weight:15 parts of cloves, agalloch eaglewood 15 Part, 12 parts of dried orange peel, 12 parts of rascal, 15 parts of the calyx and receptacle of a persimmon, 12 parts of radix bupleuri.
The preparation method of the traditional Chinese herbal decoction of cure hiccup, comprises the following steps:
(1)The raw material configured is put into immersion 50-60 minutes in 35-45 DEG C of water, feed liquid mass ratio is 1:(6-7);
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3-4 minutes and boils 30-40 minutes, completes to filter decoction after decocting first Go out;
(3)Water is added again, and feed liquid mass ratio is 1:(2-3), intense fire is changed to slow fire and boils 25-35 minutes after being heated to boiling, Decoction is filtered out after completing secondary decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
Preferably, the preparation method of the traditional Chinese herbal decoction of cure hiccup, comprises the following steps:
(1)The raw material configured is put into 40 DEG C of water and soaked 50 minutes, feed liquid mass ratio is 1:6;
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3 minutes and is boiled 35 minutes, completes to filter out decoction after decocting first;
(3)Water is added again, and feed liquid mass ratio is 1:2, intense fire is changed to slow fire and boiled 30 minutes after being heated to boiling, completes secondary Decoction is filtered out after decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
The effect of Chinese medicine material employed in the present invention is specific is as follows:
Cloves, acrid flavour are warm-natured.Enter kidney, spleen, stomach.Function:Warm stomach down, warming kidney and enhancing yang.Cure mainly:Stomach cold hiccup is vomitted, gastral cavity abdomen Crymodynia, hernia pain, impotence flaccidity of lower limbs caused by the insufficiency of the kidney yang.
Agalloch eaglewood, acrid flavour, hardship, slightly warm in nature.Enter spleen, stomach, kidney channel.Function:Promoting qi circulation and relieving pain, drop in inverse adjust, warm kidney receives gas.It is main Control:Cold obstruction causing qi stagnation, chest and abdomen are swollen it is vexed have a pain, gastrofrigid vomiting, hiccup, void asthma, phlegm and retained fluid cough and asthma.
Dried orange peel, it is bitter, pungent, it is warm-natured.Enter spleen, lung channel.Function:Regulating qi-flowing for harmonizing stomach is eliminating dampness and eliminating phlegm.Cure mainly:Abdominal fullness and distention, gastric disorder causing nausea Vomiting, poor appetite, many coughs of phlegm.
Rascal, it is bitter, pungent, it is warm-natured.Enter liver, courage, stomach.Function:Relieving stagnant and resolving masses, soothing liver-qi stagnation.Cure mainly:The distending pain in hypochondrium, Swollen breasts, hernia pain, accumulation of food in the stomach and intes tine due to indigestion , lumps in the chest and abdomen.
The calyx and receptacle of a persimmon, it is bitter, puckery, it is mild-natured.Enter stomach.Function:Sending down abnormally ascending stops oh.Cure mainly:The disease of hiccup caused by stomach Qi rising.
Radix bupleuri, acrid flavour, hardship, cold nature.Return liver, courage, lung channel.In inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever. For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, the prolapse of uterus, prolapse of the anus.
Beneficial effects of the present invention are as follows:
The formula of the present invention, scientific and reasonable compatibility, in this traditional Chinese herbal decoction, cloves plays warm stomach down effect, and agalloch eaglewood plays drop Acted in inverse tune, dried orange peel plays a part of regulating qi-flowing for harmonizing stomach, and rascal and radix bupleuri play a part of soothing liver-qi stagnation, and the calyx and receptacle of a persimmon, which plays sending down abnormally ascending, to be stopped Effect oh, above-mentioned medicinal material complement each other, and have inverse pleasant drop, resolving sputum preventing or arresting vomiting, the multiple efficacies such as liver and stomach of relaxing, have to hiccup Good therapeutic effect.The traditional Chinese herbal decoction have specific aim is high, therapeutic effect is good, it is efficient it is high, human body is had no toxic side effect Advantage.
Embodiment
Embodiment 1
A kind of traditional Chinese herbal decoction of cure hiccup, is prepared by the raw material of following parts by weight:Cloves 12-18 parts, agalloch eaglewood 12-18 Part, dried orange peel 10-14 parts, rascal 10-14 parts, calyx and receptacle of a persimmon 12-18 parts, radix bupleuri 10-14 parts.
The preparation method of the traditional Chinese herbal decoction of cure hiccup as described above, comprises the following steps:
(1)The raw material configured is put into immersion 50-60 minutes in 35-45 DEG C of water, feed liquid mass ratio is 1:(6-7);
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3-4 minutes and boils 30-40 minutes, completes to filter decoction after decocting first Go out;
(3)Add water again, the addition weight ratio of raw material and water is 1 Chinese medicine:(2-3)Water, intense fire are changed to after being heated to boiling Slow fire boils 25-35 minutes, filters out decoction after completing secondary decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
Embodiment 2
A kind of traditional Chinese herbal decoction of cure hiccup, is prepared by the raw material of following parts by weight:Cloves 15g, agalloch eaglewood 15g, dried orange peel 12g, rascal 12g, calyx and receptacle of a persimmon 15g, radix bupleuri 12g.
The preparation method of the traditional Chinese herbal decoction of cure hiccup according to claim 3, comprises the following steps:
(1)The raw material configured is put into 40 DEG C of water and soaked 50 minutes, feed liquid mass ratio is 1:6;
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3 minutes and is boiled 35 minutes, completes to filter out decoction after decocting first;
(3)Add water again, the addition weight ratio of raw material and water is 1 Chinese medicine:2 water, intense fire are changed to slow fire after being heated to boiling Boil 30 minutes, filter out decoction after completing secondary decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
A kind of formula of traditional Chinese medicinal decoction for treating acne that 3-14 of the embodiment of the present invention is provided is shown in Table 1-2, its preparation method with Embodiment 2 is identical.
Comparative example 1
A kind of traditional Chinese herbal decoction of cure hiccup, is prepared by the raw material of following parts by weight:Cloves 6g, ginger 9g, calyx and receptacle of a persimmon 9g, people Join 3g.
Its preparation method is identical with the preparation method in embodiment 2.
Case is tested
1st, test method:
(1)Group technology
Random packet is taken in this experiment.By random code method treatment group and control group, wherein treatment group are randomly divided into by case is tested 150, comparative group 50, control group 50.
(2)Treatment method
Treatment group:Traditional Chinese herbal decoction in oral embodiment 2, each 200ml, three times per day.
Comparative group:Traditional Chinese herbal decoction in oral comparative example 1, each 200ml, three times per day.
Control group:Do not take this traditional Chinese herbal decoction.
2nd, curative effect determinate standard:Reference《Chinese medical disease Standardization of diagnosis and curative effect》Formulate.
(1)Recovery from illness:Hiccup symptom and sign are wholly absent;
(2)It is effective:Hiccup symptom disappears substantially, in the recent period without recurrence;
(3)Effectively:After hiccup symptom mitigation, number significantly reduce, or symptom disappears and because the factors such as diet, mood recur, and Do not influence feed etc.;
(4)It is invalid:Symptom is without improvement.
3rd, safety evaluation standard:
1 grade:Safety, has no any adverse reaction;
2 grades:Compare safety, if any adverse reaction, being not required to do any processing can continue to be administered;
3 grades:There is safety issue, there is moderate adverse reaction, can continue to be administered after processing;
4 grades:Because adverse reaction stops to test.
This result of the test is as shown in table 3.
As shown in table 3, this test of cure group actual observation 150, after continuously taking medicine 3 days, fully recover 27, effective 42 Example, effective 48, invalid 33, total effective rate 78%, total cure-remarkable-effectiveness rate 29.3%, security is 1 grade.Security during observation Index is no abnormal, has no adverse reaction.After 150 patients for the treatment of group continuously take medicine 6 days, fully recover 42, effective 57, have Effect 40, invalid 11, total effective rate 92.7%, total cure-remarkable-effectiveness rate 66%, security is 1 grade.Safety indexes are not during observation Note abnormalities, have no adverse reaction.Comparative group actual observation 50, after continuously taking medicine 3 days, fully recover 2, effective 6, effectively 13, invalid 29, total effective rate 42%, total cure-remarkable-effectiveness rate 16%, security is 2 grades, is occurred after some patientss medication of short duration The symptom such as dizzy or sleepy, this symptom disappears automatically after 1 hour.After continuous medication 6 days, fully recover 3, effective 8, have Effect 16, invalid 23, total effective rate 54%, total cure-remarkable-effectiveness rate 22%, security is 2 grades, is occurred after some patientss medication of short duration The symptom such as dizzy or sleepy, this symptom disappears automatically after 1.5 hours.Control group actual observation 50, total effective rate 0, Result of the test confirms that this traditional Chinese herbal decoction is evident in efficacy to hiccup disease, drug safety, reliable.

Claims (4)

1. a kind of traditional Chinese herbal decoction of cure hiccup, it is characterised in that be prepared by the raw material of following parts by weight:Cloves 12-18 Part, agalloch eaglewood 12-18 parts, dried orange peel 10-14 parts, rascal 10-14 parts, calyx and receptacle of a persimmon 12-18 parts, radix bupleuri 10-14 parts.
2. the traditional Chinese herbal decoction of cure hiccup as claimed in claim 1, it is characterised in that by the raw material preparation of following parts by weight Into:15 parts of cloves, 15 parts of agalloch eaglewood, 12 parts of dried orange peel, 12 parts of rascal, 15 parts of the calyx and receptacle of a persimmon, 12 parts of radix bupleuri.
3. the preparation method of the traditional Chinese herbal decoction of cure hiccup as described in claim any one of 1-2, it is characterised in that including following Step:
(1)The raw material configured is put into immersion 50-60 minutes in 35-45 DEG C of water, feed liquid mass ratio is 1:(6-7);
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3-4 minutes and boils 30-40 minutes, completes to filter decoction after decocting first Go out;
(3)Water is added again, and feed liquid mass ratio is 1:(2-3), intense fire is changed to slow fire and boils 25-35 minutes after being heated to boiling, Decoction is filtered out after completing secondary decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
4. the preparation method of the traditional Chinese herbal decoction of cure hiccup according to claim 3, it is characterised in that comprise the following steps:
(1)The raw material configured is put into 40 DEG C of water and soaked 50 minutes, feed liquid mass ratio is 1:6;
(2)Intense fire is heated to seething with excitement, and slow fire is changed to after 3 minutes and is boiled 35 minutes, completes to filter out decoction after decocting first;
(3)Water is added again, and feed liquid mass ratio is 1:2, intense fire is changed to slow fire and boiled 30 minutes after being heated to boiling, completes secondary Decoction is filtered out after decoction;
(4)By above-mentioned steps(2)And step(3)In the decoction that filters out be mixed to prepare the traditional Chinese herbal decoction of cure hiccup.
CN201711156456.7A 2017-11-20 2017-11-20 A kind of traditional Chinese herbal decoction of cure hiccup and preparation method thereof Pending CN107714836A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110876786A (en) * 2018-09-06 2020-03-13 朱玉鹏 Traditional Chinese medicine for treating hiccup

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CN102973874A (en) * 2012-11-19 2013-03-20 桐乡市龙翔街道卫生院 Traditional Chinese medicine relieving hiccup
CN104383328A (en) * 2014-11-03 2015-03-04 景东旭 Traditional Chinese medicine preparation for treating hiccup
CN107261085A (en) * 2017-06-27 2017-10-20 许文静 A kind of medicine of cure hiccup and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN102973874A (en) * 2012-11-19 2013-03-20 桐乡市龙翔街道卫生院 Traditional Chinese medicine relieving hiccup
CN104383328A (en) * 2014-11-03 2015-03-04 景东旭 Traditional Chinese medicine preparation for treating hiccup
CN107261085A (en) * 2017-06-27 2017-10-20 许文静 A kind of medicine of cure hiccup and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110876786A (en) * 2018-09-06 2020-03-13 朱玉鹏 Traditional Chinese medicine for treating hiccup

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