CN104940339A - Traditional Chinese medicine composition for treating post-apoplexy tardy epilepsy - Google Patents
Traditional Chinese medicine composition for treating post-apoplexy tardy epilepsy Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating post-apoplexy tardy epilepsy. The traditional Chinese medicine composition comprises codonopsis lancifolia, root of woolly lespedeza, rosa rugosa root, salvia bowleyana, valerian, choerospondias axillaries, huechys sanguinea de geer, scurrula parasitica, aristolochia fordiana, cordyceps sobolifera, oreas and corallium rubrum. The traditional Chinese medicine composition for treating post-apoplexy tardy epilepsy is definite in curative effect of treating post-apoplexy tardy epilepsy, free of side effects, capable of reducing the disability rate and the fatality rate and high in patient compliance through clinical verification. When a decoction of the traditional Chinese medicine composition for treating post-apoplexy tardy epilepsy is used for treating 42 patients, through treatment for 6 months, 23 patients are cured, the effect is produced on 12 patients, 2 patients are effectively treated, 5 patients are not cured, and the total effective rate is 88.1%.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy.
Background technology
Apoplexy is one of common cause of disease of adult epilepsy, and post-stroke delayed epilepsy not only affects the neurological functional recovery of patients with cerebral apoplexy, and the disability rate of apoplexy and fatality rate are obviously increased, and the life and health of people in serious threat.Current remedy measures is the Antiepileptic Drugs adopting doctor trained in Western medicine, there is no reasonable Chinese medicine composition accurately as the report for the treatment of and case.And the long-term untoward reaction of taking antuepileptic in a large number and can occur nervous system, digestive system and blood system, therefore how effectively to treat the focus that post-stroke delayed epilepsy becomes people's concern.The present inventor, by clinical practice for many years, develops a kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, satisfactory effect.
Summary of the invention
In order to realize foregoing invention object, the invention provides following technical scheme:
Treat a Chinese medicine composition for post-stroke delayed epilepsy, be made up of the crude drug of following mass ratio:
Fructus Pyracanthae ginseng 20 ~ 30 parts, Radix Lespedezae Tomentosae 20 ~ 30 parts, HONGCI rose root 9 ~ 15 parts, salvia bowleyana Dunn 9 ~ 15 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Choerospondiatis 30 ~ 50 parts, Huechys sanguinea De Geer. 1 ~ 3 part, Ramulus Scurmlae Parasificae 20 ~ 40 parts, Radix Aristolochiae Tagalae 3 ~ 9 parts, Periostracum cicadae 8 ~ 12 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 10 ~ 20 parts, seabed cypress 10 ~ 20 parts.
Fructus Pyracanthae is joined: flat, sweet, bitter.Tonify deficiency QI invigorating, stasis-dispelling and pain-killing.Cure mainly the overstrain deficiency of vital energy weak, traumatic injury, intestinal colic.
Radix Lespedezae Tomentosae: sweet, light, flat.Tonify deficiency, diuretic, invigorates blood circulation.Cure mainly asthenia, blood deficiency is dizzy, edema, tympanites, amenorrhea, dysmenorrhea.
HONGCI rose root: bitter, puckery, cold.Promoting blood circulation to remove obstruction in the collateral.Cure mainly arthritis, facial palsy.
Salvia bowleyana Dunn: bitter, be slightly cold.Blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving.Cure mainly coronary heart disease, headache, insomnia, arthralgia, hernia, hepatitis, metrorrhagia, dysmenorrhea, amenorrhea, milk is rare, prolonged lochia, traumatic injury, carbuncle, erysipelas, scabies.
Rhizoma et radix valerianae: pungent, sweet, warm, GUIXIN, Liver Channel.Calm the nerves, regulate the flow of vital energy, promoting blood circulation and stopping pain.Cure mainly malaise, insomnia is slept less; Infantile convulsion, epilepsy; Blood stasis amenorrhea, dysmenorrhea, lumbago and skelalgia, traumatic injury; Epigastric pain.
Fructus Choerospondiatis: sweet is sour, flat.Promoting flow of QI and blood, tranquilizing by nourishing the heart, removing food stagnancy, removing toxic substances.Cure mainly qi depression to blood stasis, chest pain, shortness of breath and palpitation, neurasthenia, insomnia, bronchitis, dyspepsia abdominal distention, diarrhoea, hernia, scald.
Huechys sanguinea De Geer.: flat, bitter, slightly poisonous, enters the heart, liver, gallbladder meridian.Removing blood stasis with potent drugs, eliminating stagnation, counteracting toxic substances.Cure mainly blood stasis amenorrhea, lumbago, infertile, scrofula, tinea skin ulcer, lyssodexis.
Ramulus Scurmlae Parasificae: pungent, bitter is flat.Wind-damp dispelling, bone and muscle strengthening, promoting blood circulation and detoxication.Cure mainly rheumatic arthralgia, soreness of the waist and knees, stomachache, hypogalactia, traumatic injury, sore swollen toxin.
Radix Aristolochiae Tagalae: bitter, pungent, warm, slightly poisonous.Wind-expelling pain-stopping, subduing swelling and detoxicating.Cure mainly heart peratodynia, rheumatic ostalgia, traumatic injury, infantile convulsion, venom.
Periostracum cicadae: sweet, cold, returns lung, Liver Channel.Dispelling wind and heat pathogens, relieving spasm by subduing liver-wind, improving acuity of vision and removing nebula.Cure mainly affection due to external wind and heat, heating, dizzy, pharyngalgia; At the measles initial stage, rash goes out not smooth; Infantile convulsion, night cry; Conjunctival congestion and swelling pain, pterygium.
Oreas martiana (Hopp. Et Hornsch.) Brid.: sweet, light, flat.Replenishing YIN and removing heat, tranquilizing the mind, expelling wind and removing dampness, hemostatic analgesia.Cure mainly osteopyrexia and fever, neurasthenia, rheumatalgia, demented, wound.
Seabed cypress: sweet, micro-salty, be slightly cold, return liver, the heart, lung meridian.Cough-relieving is stopped blooding, and stomach function regulating antidiarrheal, calms the nerves relieving convulsion.Cure mainly hemoptysis, vomiting, diarrhoea, irritability, palpitation with a distress feeling is confusing, infantile convulsion.
The traditional Chinese medical science is thought, post-stroke delayed epilepsy belongs to " epilepsy syndrome " of stroke in convalescent stage or sequela stage generation, and this phase basic pathogenesis is blood stasis due to qi deficiency.What YE Tian shi had " pathogen usually intruding into collateral in protracted disease is the stasis of blood " says; Errors in Medicine Corrected is then thought " convulsion is not wind, is first deficiency of vital energy, and blood vessel depletion of QI, stops and be the stasis of blood ".Blood stasis due to qi deficiency is the pathogenic factors of epilepsy after cerebral stroke seizure, is again its pathological product.The present invention adopts Fructus Pyracanthae ginseng, Radix Lespedezae Tomentosae tonify deficiency QI invigorating, blood circulation promoting and blood stasis dispelling; HONGCI rose root, salvia bowleyana Dunn promoting blood circulation to remove obstruction in the collateral; Rhizoma et radix valerianae, Fructus Choerospondiatis circulation of qi promoting are calmed the nerves; Huechys sanguinea De Geer. drastically removing blood stasis and resolving static blood; Ramulus Scurmlae Parasificae the kidney invigorating gas, with walk help QI and blood; Radix Aristolochiae Tagalae, Periostracum cicadae relieving spasm by subduing liver-wind; Oreas martiana (Hopp. Et Hornsch.) Brid. replenishing YIN and removing heat, tranquilizing the mind; Bai'an god is relieving convulsion in seabed.All medicines share, and play inrigorating qi and promoting blood circulation altogether, relieving spasm by subduing liver-wind, relieving convulsion merit of calming the nerves.
Preferably, the Chinese medicine composition of described treatment post-stroke delayed epilepsy is made up of the crude drug of following mass ratio:
Fructus Pyracanthae ginseng 23 ~ 27 parts, Radix Lespedezae Tomentosae 23 ~ 27 parts, HONGCI rose root 11 ~ 13 parts, salvia bowleyana Dunn 11 ~ 13 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Choerospondiatis 35 ~ 45 parts, Huechys sanguinea De Geer. 1 ~ 3 part, Ramulus Scurmlae Parasificae 25 ~ 35 parts, Radix Aristolochiae Tagalae 5 ~ 7 parts, Periostracum cicadae 9 ~ 11 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 13 ~ 17 parts, seabed cypress 13 ~ 17 parts.
Preferred further, the Chinese medicine composition of described treatment post-stroke delayed epilepsy is made up of the crude drug of following mass ratio:
Fructus Pyracanthae join 25 parts, Radix Lespedezae Tomentosae 25 parts, HONGCI rose root 12 parts, salvia bowleyana Dunn 12 parts, Rhizoma et radix valerianae 5 parts, Fructus Choerospondiatis 40 parts, Huechys sanguinea De Geer. 2 parts, Ramulus Scurmlae Parasificae 30 parts, Radix Aristolochiae Tagalae 6 parts, Periostracum cicadae 10 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 15 parts, seabed cypress 15 parts.
The Chinese medicine composition of described treatment post-stroke delayed epilepsy can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, the Chinese medicine composition of described treatment post-stroke delayed epilepsy can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
Compared with prior art, beneficial effect of the present invention
The Chinese medicine composition for the treatment of post-stroke delayed epilepsy provided by the invention, certainly, have no side effect, reduce disability rate and fatality rate, patient compliance is high for clinical confirmation treatment post-stroke delayed epilepsy curative effect.
Treat a Chinese medicine composition for post-stroke delayed epilepsy, clinical efficacy is summed up
1, physical data
Man 26 example in 42 examples, female 16 example; Year mean age (63.1 ± 8.7); The course of disease (6.2 ± 3.1) year.
2, diagnostic criteria
Apoplexy diagnostic criteria formulate with reference to nineteen ninety-five the 4th the cerebrovascular academic conference in the whole nation standard (the 4th the cerebrovascular academic conference in the whole nation. all kinds of diagnosis and treatment of cerebrovascular diseases will put the practical internal medicine journal of China, 1997,17:312-314.).All confirm through CT or MRI.Post stroke delayed epilepsy diagnostic criteria: the epilepsy that apoplexy occurred after two weeks, and prolonged and repeated outbreak (Chen Yangmei, Sun Hongbin, Wang Xuefeng. epilepsy therapy. Chengdu: Sichuan science tech publishing house, 2004:148; 438.), electroencephalogram visible epilepsy sample ripple is provided.
3, Therapeutic Method
Fructus Pyracanthae join 25 grams, Radix Lespedezae Tomentosae 25 grams, HONGCI rose root 12 grams, salvia bowleyana Dunn 12 grams, Rhizoma et radix valerianae 5 grams, Fructus Choerospondiatis 40 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 2 grams, Ramulus Scurmlae Parasificae 30 grams, Radix Aristolochiae Tagalae 6 grams, Periostracum cicadae 10 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 15 grams, seabed cypress 15 grams.Conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
4, therapeutic outcome
4.1, criterion of therapeutical effect: reference " Epilepsy Surgery " (Tan Qifu. Epilepsy Surgery. Nanjing: publishing house of Nanjing University, 1995:231-242.) formulate.To cure: electroencephalogram is normal, epilepsy disappears completely >=and 2 years; Effective: electroencephalogram is clearly better, seizure frequency reduces more than 75% before comparatively treating, and the outbreak intermittent time comparatively treats front > 1 year; Effective: electroencephalogram shows and taken a turn for the better, seizure frequency comparatively treats front minimizing amplitude 35% ~ 75%, and the outbreak persistent period comparatively treats front minimizing more than 1/2; Invalid: electroencephalogram is comparatively treated front without being clearly better, seizure frequency, outbreak persistent period are without improvement.
4.2, result: through treatment in 6 months, cures 23 examples, effective 12 examples, effective 2 examples, invalid 5 examples, total effective rate 88.1%.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, be by Fructus Pyracanthae join 30 grams, Radix Lespedezae Tomentosae 30 grams, HONGCI rose root 15 grams, salvia bowleyana Dunn 15 grams, Rhizoma et radix valerianae 6 grams, Fructus Choerospondiatis 50 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 3 grams, Ramulus Scurmlae Parasificae 40 grams, Radix Aristolochiae Tagalae 9 grams, Periostracum cicadae 12 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 20 grams, seabed cypress 20 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 2
A kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, be by Fructus Pyracanthae join 27 grams, Radix Lespedezae Tomentosae 27 grams, HONGCI rose root 13 grams, salvia bowleyana Dunn 13 grams, Rhizoma et radix valerianae 6 grams, Fructus Choerospondiatis 45 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 3 grams, Ramulus Scurmlae Parasificae 35 grams, Radix Aristolochiae Tagalae 7 grams, Periostracum cicadae 11 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 17 grams, seabed cypress 17 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 3
A kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, be by Fructus Pyracanthae join 25 grams, Radix Lespedezae Tomentosae 25 grams, HONGCI rose root 12 grams, salvia bowleyana Dunn 12 grams, Rhizoma et radix valerianae 5 grams, Fructus Choerospondiatis 40 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 2 grams, Ramulus Scurmlae Parasificae 30 grams, Radix Aristolochiae Tagalae 6 grams, Periostracum cicadae 10 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 15 grams, seabed cypress 15 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 4
A kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, be by Fructus Pyracanthae join 23 grams, Radix Lespedezae Tomentosae 23 grams, HONGCI rose root 11 grams, salvia bowleyana Dunn 11 grams, Rhizoma et radix valerianae 4 grams, Fructus Choerospondiatis 35 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 1 gram, Ramulus Scurmlae Parasificae 25 grams, Radix Aristolochiae Tagalae 5 grams, Periostracum cicadae 9 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 13 grams, seabed cypress 13 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 5
A kind of Chinese medicine composition for the treatment of post-stroke delayed epilepsy, be by Fructus Pyracanthae join 20 grams, Radix Lespedezae Tomentosae 20 grams, HONGCI rose root 9 grams, salvia bowleyana Dunn 9 grams, Rhizoma et radix valerianae 4 grams, Fructus Choerospondiatis 30 grams, Huechys sanguinea De Geer. (grind into powder and take after mixing it with water) 1 gram, Ramulus Scurmlae Parasificae 20 grams, Radix Aristolochiae Tagalae 3 grams, Periostracum cicadae 8 grams, Oreas martiana (Hopp. Et Hornsch.) Brid. 10 grams, seabed cypress 10 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Claims (4)
1. treat a Chinese medicine composition for post-stroke delayed epilepsy, it is characterized in that being made up of the crude drug of following mass ratio:
Fructus Pyracanthae ginseng 20 ~ 30 parts, Radix Lespedezae Tomentosae 20 ~ 30 parts, HONGCI rose root 9 ~ 15 parts, salvia bowleyana Dunn 9 ~ 15 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Choerospondiatis 30 ~ 50 parts, Huechys sanguinea De Geer. 1 ~ 3 part, Ramulus Scurmlae Parasificae 20 ~ 40 parts, Radix Aristolochiae Tagalae 3 ~ 9 parts, Periostracum cicadae 8 ~ 12 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 10 ~ 20 parts, seabed cypress 10 ~ 20 parts.
2. the Chinese medicine composition for the treatment of post-stroke delayed epilepsy as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Fructus Pyracanthae ginseng 23 ~ 27 parts, Radix Lespedezae Tomentosae 23 ~ 27 parts, HONGCI rose root 11 ~ 13 parts, salvia bowleyana Dunn 11 ~ 13 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Choerospondiatis 35 ~ 45 parts, Huechys sanguinea De Geer. 1 ~ 3 part, Ramulus Scurmlae Parasificae 25 ~ 35 parts, Radix Aristolochiae Tagalae 5 ~ 7 parts, Periostracum cicadae 9 ~ 11 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 13 ~ 17 parts, seabed cypress 13 ~ 17 parts.
3. the Chinese medicine composition for the treatment of post-stroke delayed epilepsy as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Fructus Pyracanthae join 25 parts, Radix Lespedezae Tomentosae 25 parts, HONGCI rose root 12 parts, salvia bowleyana Dunn 12 parts, Rhizoma et radix valerianae 5 parts, Fructus Choerospondiatis 40 parts, Huechys sanguinea De Geer. 2 parts, Ramulus Scurmlae Parasificae 30 parts, Radix Aristolochiae Tagalae 6 parts, Periostracum cicadae 10 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 15 parts, seabed cypress 15 parts.
4. treat the preparation method of the Chinese medicine composition of post-stroke delayed epilepsy as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105709024A (en) * | 2016-04-06 | 2016-06-29 | 徐显吉 | Traditional Chinese medicine composition for adjuvant therapy of acute epidural hematoma |
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| CN101675972A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Blood-enriching tranquillizing traditional Chinese medicine composition |
| CN102228539A (en) * | 2011-04-13 | 2011-11-02 | 吉林化工学院 | Rosa davurica total flavone extract, its extracting method and its medical use |
| CN104586987A (en) * | 2013-10-30 | 2015-05-06 | 王金广 | Traditional Chinese medicine used for treating stroke |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101675972A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Blood-enriching tranquillizing traditional Chinese medicine composition |
| CN102228539A (en) * | 2011-04-13 | 2011-11-02 | 吉林化工学院 | Rosa davurica total flavone extract, its extracting method and its medical use |
| CN104586987A (en) * | 2013-10-30 | 2015-05-06 | 王金广 | Traditional Chinese medicine used for treating stroke |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105709024A (en) * | 2016-04-06 | 2016-06-29 | 徐显吉 | Traditional Chinese medicine composition for adjuvant therapy of acute epidural hematoma |
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