CN104857197A - Traditional Chinese medicine composition for treating traumatic epilepsy - Google Patents
Traditional Chinese medicine composition for treating traumatic epilepsy Download PDFInfo
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- CN104857197A CN104857197A CN201510330287.9A CN201510330287A CN104857197A CN 104857197 A CN104857197 A CN 104857197A CN 201510330287 A CN201510330287 A CN 201510330287A CN 104857197 A CN104857197 A CN 104857197A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating traumatic epilepsy. The traditional Chinese medicine composition is prepared from the following crude drugs: rumex madaio, euonymus alatus, caesalpinia sappan, cassiope selaginoides, latifolious rush rhizome, radix paeoniae alba, conch shells, root of dichocarpum auriculatum, honeycomb, longleaf bastardtoadflax herb and concha mauritiae arabicae. The traditional Chinese medicine composition for treating traumatic epilepsy, provided by the invention, is definite in curative effect on traumatic epilepsy by clinical verifications, is free of side effects, can reduce the rate of surgery, and is high in patient compliance. With the adoption of decoction of the traditional Chinese medicine composition for treating traumatic epilepsy, 43 patients are treated for 6 months, the composition cures 24 patients, has a remarkable curative effect on 12 patients, has a slight effect on 2 patients and no effects on 5 patients, and has a total effective rate of 88.4%.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of Chinese medicine composition for the treatment of traumatic epilepsy.
Background technology
Traumatic epilepsy accounts for 10% of epilepsy number, is one of serious complication of craniocerebral injury, once occur, most of patients often continues more than 10 years.And the long-term untoward reaction of taking antuepileptic in a large number and can occur nervous system, digestive system and blood system, and there is quite a few patient to produce drug resistance gradually at therapeutic process, progress is intractable epilepsy, even needs operative treatment, has a strong impact on the quality of life of patient.Therefore how the focus that traumatic epilepsy becomes people's concern is effectively treated.The present inventor, by clinical practice for many years, develops a kind of Chinese medicine composition for the treatment of traumatic epilepsy, satisfactory effect.
Summary of the invention
In order to realize foregoing invention object, the invention provides following technical scheme:
Treat a Chinese medicine composition for traumatic epilepsy, be made up of the crude drug of following mass ratio:
Radix Rumicis 9 ~ 15 parts, Ramulus Euonymi 6 ~ 10 parts, Lignum Sappan 3 ~ 9 parts, Herba Cassiopes selaginoidis 15 ~ 25 parts, Juncus amplifolius A. Camus 3 ~ 9 parts, the Radix Paeoniae Alba 20 ~ 40 parts, Concha rapanae thomasianae 9 ~ 15 parts, sow grass 6 ~ 12 parts, 3 ~ 5 parts, Nidus Vespae, Herba Thesii Longifolii 6 ~ 12 parts, Concha Erosariae seu Cypraeae 10 ~ 20 parts.
The pharmacological action of raw material of Chinese medicine medicine of the present invention is as follows:
Radix Rumicis: bitter, pungent, cool.Heat-clearing and toxic substances removing, cooling blood for hemostasis, removing blood stasis to reduce swelling, relieving constipation, parasite killing.Cure mainly pulmonary tuberculosis hemoptysis, lung abscess, spit blood, the stagnant stomachache of the stasis of blood, traumatic injury, constipation, mumps, carbuncle pyogenic infections from tumour or sore, scald, scabies, eczema.
Ramulus Euonymi: removing blood stasis stimulates the menstrual flow, removing toxic substances and promoting subsidence of swelling, parasite killing.Zhu Zhi mass in the abdomen lump, trusted subordinate's pain, amenorrhea, dysmenorrhea, metrorrhagia and metrostaxis, the stagnant stomachache of the stasis of blood in puerperal, retention of lochia, puerperal agalactia, hernia, severe and migratory arthralgia arthralgia pain, skin ulcer swell, traumatic pain, abdominal pain due to worm stagnation, scald, venom, rheumatalgia, dry cough catch a cold.
Lignum Sappan: sweet, salty, pungent, flat, GUIXIN, Liver Channel.Invigorate blood circulation and cure the wound, blood stasis dispelling stimulates the menstrual flow.Cure mainly traumatic injury, the fracture injury of tendon and muscle, the stasis of blood is stagnant to swell and ache; Amenorrhea due to stagnation of blood, postpartum stagnation is suffered from abdominal pain, dysmenorrhea, trusted subordinate's pain, carbuncle sore tumefacting virus etc.
Herba Cassiopes selaginoidis: pungent, micro-hardship, flat.Circulation of qi promoting, invigorates blood circulation, and pain relieving is calmed the nerves.Cure mainly stagnation of liver-QI and stomach-QI, side of body rib abdominal distention, rheumatic arthralgia, traumatic injury, insomnia.
Juncus amplifolius A. Camus: flat, pungent, micro-hardship.Regulating QI to relieve pain, regulating menstruation and activating blood.Cure mainly stagnation of QI due to depression of the liver, pain in chest and hypochondrium, menoxenia, metrorrhagia leukorrhagia.
The Radix Paeoniae Alba: bitter, acid, to be slightly cold, returns liver, spleen channel.Nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG.Cure mainly liver-blood deficiency and blood deficiency menoxenia, the breast side of body epigastric pain of incoordination between the liver and spleen or the anxious pain of extremity contraction, the headache of excessive rising of liver-YANG is dizzy.
Concha rapanae thomasianae: salty, cold.Spasmolytic, antacid, dissipating phlegm and resolving masses.Cure mainly gastric and duodenal ulcers, neurasthenia, spasm of the limbs, chronic osteomyelitis, tuberculous lymphadenitis.
Sow grass: bitter, cold.Removing damp-heat, eliminating stagnation is reduced phlegm.Cure mainly jaundice due to damp-heat, carbuncle sore tumefacting virus, scrofula, phlegm-heat cough, epilepsy.
Nidus Vespae: sweet, flat, returns stomach warp.Detoxicating and killing parasites, wind-expelling pain-stopping.Shennong's Herbal cloud: " main infantile convulsion Chi Zong, cold and heat pathogen, insane disease, perianal abscess.”
Herba Thesii Longifolii: pungent, micro-hardship, cool.To induce sweat heat clearing away, expelling wind and relieving convulsion.Cure mainly flu, heatstroke, sural spasm, infantile pneumonia, infantile convulsion, infantile malnutrition.
Concha Erosariae seu Cypraeae: salty, flat, returns Liver Channel.Suppressing the hyperactive liver and subsiding YANG, tranquillizing the mind by relieving convulsion, liver heat removing and eyesight improving.Cure mainly excessive rising of liver-YANG, have a dizzy spell; Palpitation with fear insomnia; Cataract, blurred vision dim eyesight.
Epilepsy belongs to categories such as the traditional Chinese medical science " epilepsy syndrome " " epilepsys ".Its cause of disease is complicated, mainly " shies " relevant (Niu Zhizun, Huang Mi such as " deficiency of vital energy " " deficiency of YIN " " blood deficiency " " stagnation of QIs " to " expectorant " " wind " " stasis of blood " " fire ", Ma Zuofeng, Deng. the Modern Literature research of the sick position of epilepsy tcm causa morbi. the new traditional Chinese medical science, 2014,46:193-196.).Chinese medicine is thought, brain is clear key, the house of mental activity, after craniocerebral injury obstruction of collaterals by blood stasis, phlegm and qi stasis, even by ailment said due to cold or exposure disturbance, therefore sees unconsciousness, two fixed staring upward, gurgling with sputum, the symptoms such as limbs tic.The cause of disease of visible traumatic epilepsy mainly " stasis of blood " " expectorant " " stagnation of QI " " wind ".The many courses of disease of traumatic epilepsy are long, and non-high dose of the pertinacious phlegm stasis of blood of a specified duration can not be broken its stasis of blood and amassed, therefore the present invention adopts Radix Rumicis, Ramulus Euonymi, Lignum Sappan removing blood stasis stimulates the menstrual flow; Herba Cassiopes selaginoidis, Juncus amplifolius A. Camus promoting flow of QI and blood, to make blood circulation depending on qi flow; The Radix Paeoniae Alba is nourished blood yin fluid astringing, anti-removing blood stasis circulation of qi promoting consumption impairing the liver blood, and it is anxious to alleviate extremity contraction; Concha rapanae thomasianae, sow grass eliminating stagnation are reduced phlegm; Nidus Vespae, Herba Thesii Longifolii are expellingged wind and relieving convulsion; Concha Erosariae seu Cypraeae tranquillizing the mind by relieving convulsion.All medicines share, and play removing blood stasis circulation of qi promoting altogether, eliminating stagnation is reduced phlegm, the merit of expellingging wind and relieving convulsion.
Preferably, the Chinese medicine composition of described treatment traumatic epilepsy is made up of the crude drug of following mass ratio:
Radix Rumicis 11 ~ 13 parts, Ramulus Euonymi 7 ~ 9 parts, Lignum Sappan 5 ~ 7 parts, Herba Cassiopes selaginoidis 18 ~ 22 parts, Juncus amplifolius A. Camus 5 ~ 7 parts, the Radix Paeoniae Alba 25 ~ 35 parts, Concha rapanae thomasianae 11 ~ 13 parts, sow grass 8 ~ 10 parts, 3 ~ 5 parts, Nidus Vespae, Herba Thesii Longifolii 8 ~ 10 parts, Concha Erosariae seu Cypraeae 13 ~ 17 parts.
Preferred further, the Chinese medicine composition of described treatment traumatic epilepsy is made up of the crude drug of following mass ratio:
Radix Rumicis 12 parts, Ramulus Euonymi 8 parts, Lignum Sappan 6 parts, Herba Cassiopes selaginoidis 20 parts, Juncus amplifolius A. Camus 6 parts, the Radix Paeoniae Alba 30 parts, Concha rapanae thomasianae 12 parts, sow grass 9 parts, 4 parts, Nidus Vespae, Herba Thesii Longifolii 9 parts, Concha Erosariae seu Cypraeae 15 parts.
The Chinese medicine composition of described treatment traumatic epilepsy can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, the Chinese medicine composition of described treatment traumatic epilepsy can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
compared with prior art, beneficial effect of the present invention
The Chinese medicine composition for the treatment of traumatic epilepsy provided by the invention, certainly, have no side effect, decrease operability, patient compliance is high for clinical confirmation treatment traumatic epilepsy curative effect.
treat a Chinese medicine composition for traumatic epilepsy, clinical efficacy is summed up
1 physical data
Man 26 example in 43 examples, female 17 example; Year mean age (39.1 ± 8.7); Classify according to types of epilepsy: grand mal 11 example, limitation outbreak 10 example, petit mal 16 example, psychomotor attack 6 example.
2 diagnostic criterias
Reference " neurosurgery " (Wang Zhongcheng. neurosurgery. Wuhan: Hubei science tech publishing house, 1998:365.) formulate.1. premorbid has brain injury medical history; 2. ictal disturbance of consciousness, twitches, faints, binocular hangs oneself, slobbering etc.; 3. EEG (electrocardiogram) examination has epilepsy wave mode to occur; 4. CT or MRI scanning has brain spot, brain atrophy, penetrates brain diverticulum etc.
3 Therapeutic Method
Radix Rumicis 12 grams, Ramulus Euonymi 8 grams, Lignum Sappan 6 grams, Herba Cassiopes selaginoidis 20 grams, Juncus amplifolius A. Camus 6 grams, the Radix Paeoniae Alba 30 grams, Concha rapanae thomasianae 12 grams, sow grass 9 grams, 4 grams, Nidus Vespae, Herba Thesii Longifolii 9 grams, Concha Erosariae seu Cypraeae 15 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
4 therapeutic outcomes
4.1 criterions of therapeutical effect: reference " Epilepsy Surgery " (Tan Qifu. Epilepsy Surgery. Nanjing: publishing house of Nanjing University, 1995:231-242.) formulate.To cure: electroencephalogram is normal, epilepsy disappears completely >=and 2 years; Effective: electroencephalogram is clearly better, seizure frequency reduces more than 75% before comparatively treating, and the outbreak intermittent time comparatively treats front > 1 year; Effective: electroencephalogram shows and taken a turn for the better, seizure frequency comparatively treats front minimizing amplitude at 35%-75%, and the outbreak persistent period comparatively treats front minimizing more than 1/2; Invalid: electroencephalogram is comparatively treated front without being clearly better, seizure frequency, outbreak persistent period are without improvement.
4.2 results: through treatment in 6 months, cure 24 examples, effective 12 examples, effective 2 examples, invalid 5 examples, total effective rate 88.4%.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for the treatment of traumatic epilepsy, by Radix Rumicis 15 grams, Ramulus Euonymi 10 grams, Lignum Sappan 9 grams, Herba Cassiopes selaginoidis 25 grams, Juncus amplifolius A. Camus 9 grams, the Radix Paeoniae Alba 40 grams, Concha rapanae thomasianae 15 grams, sow grass 12 grams, 5 grams, Nidus Vespae, Herba Thesii Longifolii 12 grams, Concha Erosariae seu Cypraeae 20 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 2
A kind of Chinese medicine composition for the treatment of traumatic epilepsy, by Radix Rumicis 13 grams, Ramulus Euonymi 9 grams, Lignum Sappan 7 grams, Herba Cassiopes selaginoidis 22 grams, Juncus amplifolius A. Camus 7 grams, the Radix Paeoniae Alba 35 grams, Concha rapanae thomasianae 13 grams, sow grass 10 grams, 5 grams, Nidus Vespae, Herba Thesii Longifolii 10 grams, Concha Erosariae seu Cypraeae 17 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 3
A kind of Chinese medicine composition for the treatment of traumatic epilepsy, by Radix Rumicis 12 grams, Ramulus Euonymi 8 grams, Lignum Sappan 6 grams, Herba Cassiopes selaginoidis 20 grams, Juncus amplifolius A. Camus 6 grams, the Radix Paeoniae Alba 30 grams, Concha rapanae thomasianae 12 grams, sow grass 9 grams, 4 grams, Nidus Vespae, Herba Thesii Longifolii 9 grams, Concha Erosariae seu Cypraeae 15 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 4
A kind of Chinese medicine composition for the treatment of traumatic epilepsy, by Radix Rumicis 11 grams, Ramulus Euonymi 7 grams, Lignum Sappan 5 grams, Herba Cassiopes selaginoidis 18 grams, Juncus amplifolius A. Camus 5 grams, the Radix Paeoniae Alba 25 grams, Concha rapanae thomasianae 11 grams, sow grass 8 grams, 3 grams, Nidus Vespae, Herba Thesii Longifolii 8 grams, Concha Erosariae seu Cypraeae 13 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 5
A kind of Chinese medicine composition for the treatment of traumatic epilepsy, by Radix Rumicis 9 grams, Ramulus Euonymi 6 grams, Lignum Sappan 3 grams, Herba Cassiopes selaginoidis 15 grams, Juncus amplifolius A. Camus 3 grams, the Radix Paeoniae Alba 20 grams, Concha rapanae thomasianae 9 grams, sow grass 6 grams, 3 grams, Nidus Vespae, Herba Thesii Longifolii 6 grams, Concha Erosariae seu Cypraeae 10 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Claims (4)
1. treat a Chinese medicine composition for traumatic epilepsy, it is characterized in that being made up of the crude drug of following mass ratio:
Radix Rumicis 9 ~ 15 parts, Ramulus Euonymi 6 ~ 10 parts, Lignum Sappan 3 ~ 9 parts, Herba Cassiopes selaginoidis 15 ~ 25 parts, Juncus amplifolius A. Camus 3 ~ 9 parts, the Radix Paeoniae Alba 20 ~ 40 parts, Concha rapanae thomasianae 9 ~ 15 parts, sow grass 6 ~ 12 parts, 3 ~ 5 parts, Nidus Vespae, Herba Thesii Longifolii 6 ~ 12 parts, Concha Erosariae seu Cypraeae 10 ~ 20 parts.
2. the Chinese medicine composition for the treatment of traumatic epilepsy as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Radix Rumicis 11 ~ 13 parts, Ramulus Euonymi 7 ~ 9 parts, Lignum Sappan 5 ~ 7 parts, Herba Cassiopes selaginoidis 18 ~ 22 parts, Juncus amplifolius A. Camus 5 ~ 7 parts, the Radix Paeoniae Alba 25 ~ 35 parts, Concha rapanae thomasianae 11 ~ 13 parts, sow grass 8 ~ 10 parts, 3 ~ 5 parts, Nidus Vespae, Herba Thesii Longifolii 8 ~ 10 parts, Concha Erosariae seu Cypraeae 13 ~ 17 parts.
3. the Chinese medicine composition for the treatment of traumatic epilepsy as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Radix Rumicis 12 parts, Ramulus Euonymi 8 parts, Lignum Sappan 6 parts, Herba Cassiopes selaginoidis 20 parts, Juncus amplifolius A. Camus 6 parts, the Radix Paeoniae Alba 30 parts, Concha rapanae thomasianae 12 parts, sow grass 9 parts, 4 parts, Nidus Vespae, Herba Thesii Longifolii 9 parts, Concha Erosariae seu Cypraeae 15 parts.
4. treat the preparation method of the Chinese medicine composition of traumatic epilepsy as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194136A (en) * | 2015-11-02 | 2015-12-30 | 魏超 | Traditional Chinese medicine composition for treating syndromes caused after failure of lumbar surgery |
| CN105194324A (en) * | 2015-09-07 | 2015-12-30 | 何健 | Traditional Chinese medicine composition for treating traumatic epilepsy |
| CN106075316A (en) * | 2016-08-22 | 2016-11-09 | 李若龙 | A kind of Chinese and Western compound preparation treating traumatic epilepsy and preparation method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101564439A (en) * | 2008-04-22 | 2009-10-28 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparation of medicament for treating epilepsy |
| CN103446524A (en) * | 2012-05-30 | 2013-12-18 | 吕奎荣 | Traditional Chinese medicine composition for treating epilepsy |
| CN104069454A (en) * | 2014-02-04 | 2014-10-01 | 朱峰 | Traditional Chinese medicine for treating epilepsy |
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2015
- 2015-06-16 CN CN201510330287.9A patent/CN104857197A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101564439A (en) * | 2008-04-22 | 2009-10-28 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparation of medicament for treating epilepsy |
| CN103446524A (en) * | 2012-05-30 | 2013-12-18 | 吕奎荣 | Traditional Chinese medicine composition for treating epilepsy |
| CN104069454A (en) * | 2014-02-04 | 2014-10-01 | 朱峰 | Traditional Chinese medicine for treating epilepsy |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194324A (en) * | 2015-09-07 | 2015-12-30 | 何健 | Traditional Chinese medicine composition for treating traumatic epilepsy |
| CN105194136A (en) * | 2015-11-02 | 2015-12-30 | 魏超 | Traditional Chinese medicine composition for treating syndromes caused after failure of lumbar surgery |
| CN106075316A (en) * | 2016-08-22 | 2016-11-09 | 李若龙 | A kind of Chinese and Western compound preparation treating traumatic epilepsy and preparation method |
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Application publication date: 20150826 |