CN104918953A - 抗霉浆菌的亚单位疫苗 - Google Patents
抗霉浆菌的亚单位疫苗 Download PDFInfo
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Abstract
本发明提供抗霉浆菌的亚单位疫苗,特别是合适作为抗霉浆菌的亚单位疫苗的活性成分的蛋白质及以其制得的疫苗。所述蛋白质经实验证实可引发足够强度的免疫反应而避免猪只感染霉浆菌。所述疫苗可含有一种前述的蛋白质作为活性成分,或含有两种以上所述的蛋白质而形成鸡尾酒疫苗的形式。本发明的疫苗不仅较惯用疫苗更具安全性,同时具有相当、甚至是更优异的免疫效果。
Description
PCT国内申请,说明书已公开。
Claims (1)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2013/071379 WO2014121433A1 (zh) | 2013-02-05 | 2013-02-05 | 抗霉浆菌的亚单位疫苗 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104918953A true CN104918953A (zh) | 2015-09-16 |
CN104918953B CN104918953B (zh) | 2019-04-02 |
Family
ID=51299148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380066435.XA Active CN104918953B (zh) | 2013-02-05 | 2013-02-05 | 抗霉浆菌的亚单位疫苗 |
Country Status (14)
Country | Link |
---|---|
US (7) | US9561267B2 (zh) |
EP (3) | EP2955192B1 (zh) |
JP (1) | JP6113306B2 (zh) |
KR (7) | KR101764750B1 (zh) |
CN (1) | CN104918953B (zh) |
BR (1) | BR112015018444A2 (zh) |
DK (1) | DK2955192T3 (zh) |
ES (1) | ES2812552T3 (zh) |
MX (2) | MX370715B (zh) |
PH (1) | PH12015501716A1 (zh) |
RU (1) | RU2636459C2 (zh) |
TW (1) | TWI609878B (zh) |
UA (2) | UA116431C2 (zh) |
WO (1) | WO2014121433A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108026538A (zh) * | 2015-12-28 | 2018-05-11 | 财团法人农业科技研究院 | 猪圆环病毒2型的外鞘蛋白质的制备方法及含该外鞘蛋白质的医药组合物 |
CN110891597A (zh) * | 2017-11-01 | 2020-03-17 | 财团法人农业科技研究院 | 防治家禽滑膜霉浆菌感染的组合物 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX368864B (es) * | 2013-11-21 | 2019-10-18 | Agricultural Tech Res Inst | Composicion para prevenir infeccion por mycoplasma spp. |
AU2015287993B2 (en) * | 2014-07-07 | 2020-10-29 | Liferaft Biosciences, Inc. | A poloxamer composition free of long circulating material and methods for production and uses thereof |
CN106139137A (zh) * | 2015-03-30 | 2016-11-23 | 普莱柯生物工程股份有限公司 | 一种疫苗组合物及其应用 |
WO2017011919A1 (en) * | 2015-07-22 | 2017-01-26 | University Of Saskatchewan | Mycoplasma vaccines and uses thereof |
TWI606839B (zh) * | 2016-08-09 | 2017-12-01 | 財團法人農業科技研究院 | 防治豬鼻黴漿菌感染之組合物及生產該組合物的方法 |
EP3778626A1 (en) * | 2016-08-09 | 2021-02-17 | Agricultural Technology Research Institute | Composition for preventing and treating mycoplasma hyorhinis infection, and method for producing said composition |
RU2737971C1 (ru) * | 2020-05-22 | 2020-12-07 | Эгрикалчурал Текнолоджи Рисерч Инститьют | Композиция для профилактики и лечения инфекции mycoplasma hyorhinis и способ получения указанной композиции |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0359919A2 (en) * | 1988-06-29 | 1990-03-28 | Ml Technology Ventures, L.P. | Recombinant mycoplasma hyopneumoniae antigen and uses therefor |
CN101217974A (zh) * | 2005-07-07 | 2008-07-09 | 伯尔尼大学 | 支原体亚单位疫苗 |
Family Cites Families (11)
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EP0571648A1 (en) * | 1992-05-26 | 1993-12-01 | Chung-Nan Weng | Vaccine protecting against mycoplasmal pneumonia |
EP0603406B1 (en) * | 1992-05-29 | 2001-09-19 | Nippon Zeon Co., Ltd. | Fowl mycoplasma antigen, gene thereof, recombinant vector containing said gene, and vaccine prepared by utilizing the same |
DE19816334A1 (de) | 1998-04-11 | 1999-10-14 | Krupp Uhde Gmbh | Elektrolyseapparat zur Herstellung von Halogengasen |
AU6128900A (en) | 1999-09-29 | 2001-04-05 | Pfizer Products Inc. | Nucleic acids and proteins of the mycoplasma hyopneumoniae mph3 gene and uses thereof |
US6537552B1 (en) | 1999-10-19 | 2003-03-25 | Iowa State University Research Foundation | Vaccine adjuvant |
CZ305781B6 (cs) * | 2001-07-02 | 2016-03-16 | Zoetis Services Llc | Výroba vakcíny Mycoplasma hyopneumoniae |
WO2005003313A2 (en) * | 2003-06-26 | 2005-01-13 | Lifesensors, Inc. | Methods and compositions for enhanced protein expression and purification |
BR0306775A (pt) * | 2003-12-23 | 2005-10-04 | Conselho Nacional Cnpq | Polinucleotìdeos codificadores de atividades do cromossomo da bactéria mycoplasma hyopneumoniae |
TW200951219A (en) | 2008-05-06 | 2009-12-16 | Academia Sinica | An improved SUMO fusion protein system for effective production of native proteins |
EP2398486A4 (en) * | 2009-02-20 | 2012-11-21 | Cdg Therapeutics Inc | Compositions and methods for preventing and / or treating cancer by pa-card |
CN101638435B (zh) * | 2009-09-04 | 2011-11-16 | 暨南大学 | 一种蓝藻病毒蛋白n突变体、其修饰衍生物及应用 |
-
2013
- 2013-02-05 KR KR1020177018450A patent/KR101764750B1/ko active IP Right Grant
- 2013-02-05 KR KR1020177018449A patent/KR101773486B1/ko active IP Right Grant
- 2013-02-05 KR KR1020177018446A patent/KR101831318B1/ko active IP Right Grant
- 2013-02-05 KR KR1020177018451A patent/KR101775435B1/ko active IP Right Grant
- 2013-02-05 DK DK13874332.3T patent/DK2955192T3/da active
- 2013-02-05 BR BR112015018444-8A patent/BR112015018444A2/pt not_active Application Discontinuation
- 2013-02-05 MX MX2017014670A patent/MX370715B/es unknown
- 2013-02-05 JP JP2015555527A patent/JP6113306B2/ja active Active
- 2013-02-05 RU RU2015137851A patent/RU2636459C2/ru active
- 2013-02-05 ES ES13874332T patent/ES2812552T3/es active Active
- 2013-02-05 EP EP13874332.3A patent/EP2955192B1/en active Active
- 2013-02-05 KR KR1020177018447A patent/KR101838160B1/ko active IP Right Grant
- 2013-02-05 KR KR1020157020568A patent/KR101758778B1/ko active IP Right Grant
- 2013-02-05 MX MX2015010102A patent/MX355078B/es active IP Right Grant
- 2013-02-05 EP EP20175177.3A patent/EP3733690A1/en not_active Withdrawn
- 2013-02-05 CN CN201380066435.XA patent/CN104918953B/zh active Active
- 2013-02-05 UA UAA201707071A patent/UA116431C2/uk unknown
- 2013-02-05 KR KR1020177018448A patent/KR101775434B1/ko active IP Right Grant
- 2013-02-05 US US14/765,512 patent/US9561267B2/en active Active
- 2013-02-05 EP EP20175179.9A patent/EP3733691A1/en not_active Withdrawn
- 2013-02-05 WO PCT/CN2013/071379 patent/WO2014121433A1/zh active Application Filing
- 2013-02-06 TW TW102104517A patent/TWI609878B/zh active
- 2013-05-02 UA UAA201508540A patent/UA115348C2/uk unknown
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2015
- 2015-08-04 PH PH12015501716A patent/PH12015501716A1/en unknown
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2016
- 2016-12-19 US US15/383,962 patent/US9750790B2/en active Active
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2017
- 2017-03-08 US US15/453,691 patent/US9775893B2/en active Active
- 2017-03-08 US US15/453,660 patent/US9750791B2/en active Active
- 2017-03-08 US US15/453,599 patent/US9730990B2/en active Active
- 2017-03-08 US US15/453,684 patent/US9750792B2/en active Active
- 2017-03-08 US US15/453,760 patent/US9757441B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0359919A2 (en) * | 1988-06-29 | 1990-03-28 | Ml Technology Ventures, L.P. | Recombinant mycoplasma hyopneumoniae antigen and uses therefor |
CN101217974A (zh) * | 2005-07-07 | 2008-07-09 | 伯尔尼大学 | 支原体亚单位疫苗 |
Non-Patent Citations (1)
Title |
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GENBANK DATABASE: ""Accession NO:YP_115778,pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [Mycoplasma hyopneumoniae]"", 《GENBANK DATABASE》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108026538A (zh) * | 2015-12-28 | 2018-05-11 | 财团法人农业科技研究院 | 猪圆环病毒2型的外鞘蛋白质的制备方法及含该外鞘蛋白质的医药组合物 |
CN110891597A (zh) * | 2017-11-01 | 2020-03-17 | 财团法人农业科技研究院 | 防治家禽滑膜霉浆菌感染的组合物 |
CN110891597B (zh) * | 2017-11-01 | 2023-09-22 | 财团法人农业科技研究院 | 防治家禽滑膜霉浆菌感染的组合物 |
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