CN104906434A - Cough expelling and phlegm reduction drink for treating chronic bronchitis and preparation method of cough expelling and phlegm reduction drink - Google Patents

Cough expelling and phlegm reduction drink for treating chronic bronchitis and preparation method of cough expelling and phlegm reduction drink Download PDF

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CN104906434A
CN104906434A CN201510376142.2A CN201510376142A CN104906434A CN 104906434 A CN104906434 A CN 104906434A CN 201510376142 A CN201510376142 A CN 201510376142A CN 104906434 A CN104906434 A CN 104906434A
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radix
cough
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chronic bronchitis
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王艳红
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Abstract

The invention discloses a cough expelling and phlegm reduction drink for treating chronic bronchitis. The cough expelling and phlegm reduction drink is prepared from the following main raw materials in parts by weight: 15-20 parts of liquorice, 4-8 parts dragon bone, 18-25 parts of ampelopsis japonica, 10-20 parts of white mulberry root-bark, 20-30 parts of pears, 30-40 parts of American ginseng, 15-30 parts of trichosanthes kirilowii, 10-16 parts of as arum, 6-14 parts of radish, 15-28 parts of imperata cylindrical, 10-20 parts of corn, 5-15 parts of paederia foetida, 3-8 parts of loquat leaves and 8-14 parts of platycodon grandiflorum. The cough expelling and phlegm reduction drink has a remarkable effect in expelling cough, reducing phlegm and treating chronic bronchitis, can not only relieve cough, reduce phlegm and treat chronic bronchitis, but also strengthen stomach and harmonize warmer, clear heat and remove dampness, and can relieve pain caused by long-time cough expelling and phlegm reduction and chronic bronchitis of patients, and moreover as local ordinary medicinal materials are adopted, the cough expelling and phlegm reduction drink is low in price, and the economic burden of patients can be alleviated.

Description

A kind of treat chronic bronchitis dispel coughing reduce phlegm drink and preparation method thereof
Technical field
The invention belongs to traditional Chinese medicine field, relate to a kind of treat chronic bronchitis dispel coughing reduce phlegm drink and preparation method thereof.
Background technology
Chronic bronchitis is owing to infect or non-infective agent causes the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue thereof.Its pathological characteristic is bronchus glandular hyperplasia, mucilage secretion increases.Clinically have continuous more than 2 years, the symptoms such as the cough often continuing more than three months, expectoration or asthma.Early symptom is slight, how to show effect in the winter time, alleviates after the spring is warm; Late phase inflammation increases the weight of, and symptom exists all the year round, regardless of season.Progression of disease again can concurrent obstructive emphysema, pulmonary heart disease, has a strong impact on labour force and health.
The cause of disease 1. exopathogenic factor: (1) smoking is studied both at home and abroad and all proved.Smoking period is longer, and smoke which is larger, and prevalence is also higher.Symptom can be made after smoking cessation to alleviate or disappear, disease amelioration, even fully recover.(2) infective agent: infection is the key factor that development occurs chronic bronchitis, and be mainly virus and bacteriological infection, rhinovirus, myxovirus, adenovirus and respiratory syncytial virus are common.Can secondary bacterial infection on the basis that virus or virus and mycoplasma mixed infection damage air flue mucosa.Found that from Sputum culturing, is the most common with hemophilus influenza, streptococcus pneumoniae, alpha streptococcus and neisser's coccus four kinds.Though infect and have substantial connection with the morbidity of chronic bronchitis, there is no enough evidences at present and be illustrated as its starting cause of disease.Only think the secondary infection of chronic bronchitis and the key factor of aggravation pathological development.(3) chemical factors is as the chronic stimulation of irritating smog, dust, atmospheric pollution (as sulfur dioxide, nitrogen dioxide, chlorine, ozone etc.), is often one of risk factor of chronic bronchitis.Contact the workman of industrial zest dust and harmful gas, chronic bronchitis prevalence is high far beyond not contactee, therefore atmospheric pollution is also that primary disease is important brings out the cause of disease.(4) very cold is often major reason and the inducement of chronic bronchitis outbreak, and chronic bronchitis morbidity and acute exacerbation are common in cold season in winter, especially when weather changes suddenly.Cold gas stimulates respiratory tract, except weakening the defense function of upper respiratory tract mucosa, also causes bronchial smooth muscle contraction, mucosa disturbance of blood circulation and secretions to discharge difficulty etc. by reflection, is conducive to secondary infection.(5) intolerance factors according to investigations, and asthmatic bronchitis often has allergies.In patient's sputum, eosinophilic granulocyte quantity and histamine content have and increase tendency, and declaratives patient is relevant with intolerance factors.Dust, dirt demodicid mite, antibacterial, fungus, parasite, pollen and chemical gas etc., can become intolerance factors and cause a disease.2. endogenous cause of ill: (1) respiratory tract local defense and immunologic function lower normal person's respiratory tract and have perfect defense function, having filtration to sucking air, adding gentle moistening effect; The mucus cilia motion of trachea-bronchial epithelial cell mucosa, and coughre flex etc., can purify or get rid of foreign body and too much secretions; Go back immunoglobulin,exocrine (IgA) in bronchioles and alveolar, have antiviral and bacterial action, therefore, under normal circumstances, lower respiratory tract remains aseptic condition.Defence and the immunologic function of whole body or respiratory tract local weaken, and can be chronic bronchitis morbidity and provide inherent condition.The immunocyte decline of old people Chang Yin respiratory tract, the minimizing of immunoglobulin, respiratory tract defense function is degenerated, and monokaryon--mononuclear phagocyte system deterioration etc., cause prevalence higher.(2) autonomic nervous dysfunction is when the reaction of respiratory tract parasympathetic nervous is increased, and to the inoperative faint stimulation of normal person, can cause bronchoconstriction spasm, secretions increase, and produce the symptoms such as cough, expectoration, asthma.Amid all these factors, when Abwehrkraft des Koepers weakens, air flue, on the basis of sensitivity (susceptibility) in various degree, has the existence of one or more exopathogenic factors, prolonged and repeated effect, can develop into chronic bronchitis.As long-term smoking infringement respiratory mucosa, add the repeated infection of microorganism, chronic bronchitis can occur, even develop into chronic obstructive emphysema or chronic cardiopulmonary disease.
Clinical manifestation: some patients has the acute respiratory infection histories such as acute bronchitis, influenza or pneumonia before onset.Patient is everlasting and falls ill cold season, and occur cough, expectoration, especially to rise morning as work, expectorant is white mucus cystose, sticky not easily expectoration.When acute respiratory infection, symptom is aggravated rapidly.Amount of expectoration increases, and stickiness increases or is yellow purulence, occasionally has sputum mixed with blood.After chronic bronchitis recurrent exerbation, the vagus nerve sensor reactivity of bronchial mucosa increases, and parasympathetic functions is hyperfunction, can occur allergic phenomena and pant.Along with PD, cough all the year round, expectoration does not stop, and the autumn in winter aggravates.Asthmatic bronchitis patient symptom aggravation or secondary infection time, often have asthma sample to show effect, out of breath can not put down sleeping.Dyspnea is generally not obvious, but after Complicated with Pulmonary edema due to disorder of QI, along with emphysema degree increases, then dyspnea exacerbates gradually.The early stage many Absence of physical signs of primary disease.Sometimes wet and dry rale can be heard in base of lung portion.Asthmatic bronchitis can hear asthma sound after cough or dark air-breathing, during outbreak, has extensive wheezing sound.The case of long-term outbreak can have emophysematous sign.X-ray sign simple type chronic bronchitis, x-ray checks positive, or rarely seen two lung bottom textures increase thick, or in rope strip, and this is the thickening sign of bronchial wall proliferation of fibrous tissue.If merging peribronchitis, can spottiness shade overlapping on it.Bronchography, often can see bronchus distortion, what have is narrow, have in column expansion, have due to sputum retention, in blocking shape.Because around scar tissue shrinks, bronchus can be closed up in pencil.Sometimes visible bronchial wall has little diverticulum, is the performance of mucous gland opening expansion.Clinically for clarifying a diagnosis, having an X-rayed or take the photograph plain film can meet the demands.Bronchography, only for special research, does not do routine examination.
Chinese medicine occupies very important status in treatment chronic bronchitis, but in patent documentation, is not specifically designed to dispelling of chronic bronchitis for the treatment of and coughs the drink that reduces phlegm.
Summary of the invention
For the present situation of existing treatment chronic bronchitis deficiency, an object of the present invention is to provide a kind of and treats dispelling of chronic bronchitis and cough the drink that reduces phlegm, have easy to carry, action effect is obvious, alleviation of playing that can be very fast is dispelled to cough and is reduced phlegm, the effect for the treatment of chronic bronchitis, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide above-mentioned dispelling and coughs the preparation method of the drink that reduces phlegm.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from: Radix Glycyrrhizae 15-20 part, Os Draconis 4-8 part, Radix Ampelopsis 18-25 part, Cortex Mori 10-20 part, pears 20-30 part, Radix Panacis Quinquefolii 30-40 part, Fructus Trichosanthis 15-30 part, Herba Asari 10-16 part, Radix Raphani 6-14 part, Rhizoma Imperatae 15-28 part, Semen Maydis 10-20 part, fevervine 5-15 part, Folium Eriobotryae 3-8 part, Radix Platycodonis 8-14 part.
A kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, optimum ratio, take off the primary raw material stating weight proportion and be prepared from: Radix Glycyrrhizae 16-19 part, Os Draconis 5-7 part, Radix Ampelopsis 20-22 part, Cortex Mori 13-18 part, pears 23-28 part, Radix Panacis Quinquefolii 33-38 part, Fructus Trichosanthis 31-34 part, Herba Asari 13.5-14.5 part, Radix Raphani 9.5-10.5 part, Rhizoma Imperatae 23.5-24.5 part, Semen Maydis 13-18 part, fevervine 8-13 part, Folium Eriobotryae 4-7 part, Radix Platycodonis 10-12 part.
A kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, better preferred proportioning, take off the primary raw material stating weight proportion and be prepared from: 17.5 parts, Radix Glycyrrhizae, Os Draconis 6 parts, Radix Ampelopsis 21 parts, Cortex Mori 15 parts, pears 25 parts, Radix Panacis Quinquefolii 35 parts, Fructus Trichosanthis 32.5 parts, Herba Asari 14 parts, Radix Raphani 10 parts, Rhizoma Imperatae 24 parts, Semen Maydis 15 parts, fevervine 11 parts, Folium Eriobotryae 5.5 parts, Radix Platycodonis 11 parts.
Above-mentioned dispelling coughs the preparation method of the drink that reduces phlegm, and step is as follows:
(1) by pears and Radix Raphani peeling, cleaning 2-6 time, cuts into slices, is placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 60-100 mesh sieve stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, 2-6 minute is steamed after water boils, place 40-60 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, 1-5 minute is steamed after water boils, stewing after 10-20 minute, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, 3-8 minute is steamed after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) Semen Maydis is placed in large iron pan, add Semen Maydis weight 30-40 warm water doubly, little fire decocts to boiling, turn big fire after 20-40 minute until boiling and decoct 2-4 minute, stewing 20-30 minute, filters, Semen Maydis is placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing 2-4 hour is wrapped with preservative film, step (4) gained filtrate is heated to 30-40 DEG C, put into the crude drug of good seal, stir while decoct 3-7 minute, filter, filtrate cools bottling and namely obtains oral liquid.
Above-mentioned preparation method, step (1) is by pears and Radix Raphani peeling, and cleaning 3-5 is all over (preferably by pears and Radix Raphani peeling, cleaning 4 times).
Above-mentioned preparation method, Os Draconis are smashed by step (2), cross 70-90 mesh sieve stand-by (preferably smashed by Os Draconis, cross 80 mesh sieves stand-by).
Above-mentioned preparation method, step (3) steams 3-5 minute after water boils, and places 45-55 DEG C (preferably steam 4 minutes after water boils, place 50 DEG C).
Above-mentioned preparation method, steams 2-4 minute after step (3) water boils, stewing 13-18 minute (preferred water is steamed 3 minutes after boiling, stewing 15 minutes).
Above-mentioned preparation method, step (4) adds Semen Maydis weight 33-38 warm water doubly, little fire decocts to boiling, turn big fire after 25-35 minute until boiling and decoct 2-4 minute, boil in a covered pot over a slow fire and (preferably add the warm water of Semen Maydis weight 35 times in 23-28 minute, little fire decocts to boiling, turns big fire decoct 3 minutes until boiling after 30 minutes, stewing 25 minutes).
Above-mentioned preparation method, step (5) is mixed thoroughly with Mel, wraps sealing 2.5-3.5 hour (preferably mix thoroughly with Mel, wrap sealing 3 hours with preservative film) with preservative film.
Using method: for making the present invention reach optimum therapeuticing effect, gained is dispelled and is coughed the drink that reduces phlegm, and take after 1 hour after the meal three, with warm water delivery service, each 5-10ml 7 days is a course for the treatment of.
This dispel coughing the drink that reduces phlegm to cough dispelling reduce phlegm, the Be very effective of chronic bronchitis, not only alleviate to dispel to cough and reduce phlegm, treatment chronic bronchitis, can also stomach invigorating and in, clearing away heat and eliminating dampness, improve patient long-term cough because dispelling reduce phlegm, slight illness that chronic bronchitis is brought, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
A kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, the pharmacological effect of each crude drug is respectively:
Radix Glycyrrhizae: feeble QI, taste is sweet and special, and function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc., for insufficiency of heart-QI, severe palpitation, irregularly intermittent and regularly intermittent pulse, and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc.
Os Draconis: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
Radix Ampelopsis: function: heat-clearing and toxic substances removing; Removing obstruction for relieving pain; Promoting tissue regeneration and ulcer healing.Cure mainly: sore swollen toxin, scrofula, scald, eczema, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula, leucorrhea, traumatic injury, traumatic hemorrhage.
Cortex Mori: polysaccharide: mucoitin, Mulberry polysaccharide, chitin, chitosan.Also containing α-and β-amyrin, sitoesterol, volatile oil, tannin etc., hypotensive effect, diuresis, sedation and analgesia effect, antiinflammatory action, antibacterial action, anticoagulant.
Pears: the micro-acid of pears sweet in the mouth, cool in nature, enter lung, stomach warp; Have and promote the production of body fluid, moisturize, heat clearing away, to reduce phlegm, the effect of relieving the effect of alcohol; For diseases such as the dry cough caused by consumption of YIN caused by febrile disease or the deficiency of YIN, thirsty, constipation, also can be used for the diseases such as the excessive thirst caused by interior-heat, cough with asthma, expectorant is yellow.Melonidum: promote the production of body fluid, moisturize, heat clearing away, the effect such as to reduce phlegm, be applicable to consumption of body fluid caused by febrile disease excessive thirst, diabetes, heat syndrome cough, the hot mania and irritation of expectorant, dysphagic, thirsty aphonia, redness with swelling and pain of the eye, dyspepsia.Melonidum skin: clear away heart-fire, lung moistening, pathogenic fire reducing, promote the production of body fluid, nourishing kidney, nourishing YIN effect.Root, branch and leaf, flower have effect of lung moistening, expectorant heat clearing away, removing toxic substances.Pears seed: pears seed contains lignin, is a kind of soluble fiber, can dissolves in intestines, form the thin film as colloid, can be combined with cholesterol in intestines and get rid of.Pear contains boron can prevent female osteoporosis.When boron is sufficient, memory, attention, intelligence acuity can improve.Cure mainly: cure mainly cough due to heat, cough-relieving.Control and cough heat, aphasia due to apoplexy, typhoid fever is generated heat, and separates borax steam, frightened evil.Profit defecation, except harmful wind, only vexed asthma is fanatical.The cool heart of lung moistening, inflammation falls in expectorant, separates sore, alcoholism.Have reducing internal heat, treat constipation effect.
Radix Panacis Quinquefolii: cool in nature, sweet in the mouth, micro-hardship.Function cures mainly: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.Lose for deficiency of vital energy the moon, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done.Lung benefiting is cloudy, clear asthenic fire, promoting the production of body fluid to quench thirst.Control deficiency of the lung chronic cough, lose blood, dry throat and mouth, deficiency-heat is tired of tired.
Fructus Trichosanthis: Fructus Trichosanthis have antipyreticly to quench the thirst, diuresis, the effect such as relieving cough and expelling phlegm.Seed is containing fat flower fat oil; Fruit is containing triterpene saponin, organic acid, resin, saccharide, color element; Root, containing protein, saponin, acids, has inhibitory action to Gram-negative enteral pathogenic bacterium such as escherichia coli in vitro; And also have certain inhibitory action to staphylococcus, Diplococcus pneumoniae, α-hemolytic streptococcus, hemophilus influenza, Microsporon audouini and star nocardia etc.
Herba Asari: pungent, temperature.GUIXIN, lung, kidney channel, induce sweat cold expelling, and wind-expelling pain-stopping is sensible, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Radix Raphani: root is done vegetable and eaten; Seed, fresh, withered, leaf is all used as medicine: seed eliminates indigestion and phlegm; Fresh quench the thirst, aid digestion, withered profit two is just; Ye Zhi is dysentery just, and prevent dysentery; Seed oil expression is industrial and edible, seed, fresh, Ye Junke is used as medicine, function therapeutic method to keep the adverse QI flowing downwards removing food stagnancy.
Rhizoma Imperatae: return lung, stomach, urinary bladder channel.Effect cooling blood for hemostasis, clearing away heat and promoting diuresis.Cure mainly and spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, cough due to lung-heat, gastropyretic vomiting, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.
Semen Maydis: containing a large amount of nutraceutical agents in Semen Maydis, contained glutathion is anticancer factor, and the nutrient substance such as the riboflavin also contained in Semen Maydis, vitamin have very large effect to the disease such as prevention of cardiac, cancer.Can accelerate to get rid of vivotoxin containing a large amount of plant celluloses in Semen Maydis, wherein natural Vitamin E then has the function promoting cell division, slow down aging, reduction serum cholesterol, prevent dermatosis.So Semen Maydis recovers also to have certain effect to treatment comedo and small pox skin.Semen Maydis is rich in vitamin C longevity, beautification function.Nutrient substance contained by corn germ point has enhancing human metabolism, adjustment is nervous function, can play and make skin delicacy smooth, suppress, delay wrinkle generation effect, have corresponding regulating action to small pox skin.Appetizing, function of gallbladder promoting, relieving constipation, diuresis, vessel softening, delay that cell is old and weak, the Dietotherapy health of the illness such as cancer-resisting etc. is suitable for hypertension, hyperlipidemia, arteriosclerosis, old people's habitual constipation, chronic cholecystitis, urine are unlucky.
Fevervine: its sweet in the mouth, micro-hardship, property is put down.There is expelling wind and removing dampness, analgesic antidotal, promoting digestion and removing stagnation, effect of promoting blood circulation and detumescence.For bones and muscles pain due to rheumatism, traumatic injury, traumatic pain, liver and gall and gastrointestinal angor, dyspepsia, infantile malnutrition, bronchitis; Outer for dermatitis, eczema and sore swollen toxin.
Folium Eriobotryae: clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastropyretic vomiting, hiccup.Xerostomia can be treated quench one's thirst, lung-wind syndrome acne vulgaris, acne, have the effects such as heat clearing away, lung moistening, relieving cough and resolving phlegm.Radix Platycodonis: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
The present invention dispel coughing reduce phlegm drink meet Chinese medicine debate disease treatment principle, therapeutic effect is comprehensive, and affected area administration is more rapid, lasting medicine, belong to treating both the principal and secondary aspects of a disease dispel cough reduce phlegm, chronic bronchitis prescription, the Chinese medicinal material selected all has alleviation to dispel to cough and reduce phlegm, treatment chronic bronchitis, stomach invigorating and in, effect of clearing away heat and eliminating dampness, and cheap, life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of chronic bronchitis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1a kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from (getting 20g for every part): 15 parts, Radix Glycyrrhizae, Os Draconis 4 parts, Radix Ampelopsis 18 parts, Cortex Mori 10 parts, pears 20 parts, Radix Panacis Quinquefolii 30 parts, Fructus Trichosanthis 15 parts, Herba Asari 10 parts, Radix Raphani 6 parts, Rhizoma Imperatae 15 parts, Semen Maydis 10 parts, fevervine 5 parts, Folium Eriobotryae 3 parts, Radix Platycodonis 8 parts.
Above-mentioned dispelling coughs the preparation method of the drink that reduces phlegm, and step is:
(1) by pears and Radix Raphani peeling, clean 2 times, cut into slices, be placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 60 mesh sieves stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, steam 2 minutes after water boils, place 40 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, steam 1 minute after water boils, stewing after 10 minutes, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, steam 3 minutes after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) be placed in large iron pan by Semen Maydis, add the warm water of Semen Maydis weight 30 times, little fire decocts to boiling, turns big fire decoct 2 minutes until boiling after 20 minutes, stewing 20 minutes, filter, Semen Maydis was placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing is wrapped 2 hours with preservative film, step (4) gained filtrate is heated to 30 DEG C, put into the crude drug of good seal, stir while decoct 3 minutes, filter, filtrate cools bottling and namely obtains oral liquid.
embodiment 2a kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): 20 parts, Radix Glycyrrhizae, Os Draconis 8 parts, Radix Ampelopsis 25 parts, Cortex Mori 20 parts, pears 30 parts, Radix Panacis Quinquefolii 40 parts, Fructus Trichosanthis 30 parts, Herba Asari 16 parts, Radix Raphani 14 parts, Rhizoma Imperatae 28 parts, Semen Maydis 20 parts, fevervine 15 parts, Folium Eriobotryae 8 parts, Radix Platycodonis 14 parts.
Above-mentioned dispelling coughs the preparation method of the drink that reduces phlegm, and step is:
(1) by pears and Radix Raphani peeling, clean 6 times, cut into slices, be placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 100 mesh sieves stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, steam 6 minutes after water boils, place 60 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, steam 5 minutes after water boils, stewing after 20 minutes, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, steam 8 minutes after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) be placed in large iron pan by Semen Maydis, add the warm water of Semen Maydis weight 40 times, little fire decocts to boiling, turns big fire decoct 4 minutes until boiling after 40 minutes, stewing 30 minutes, filter, Semen Maydis was placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing is wrapped 4 hours with preservative film, step (4) gained filtrate is heated to 40 DEG C, put into the crude drug of good seal, stir while decoct 7 minutes, filter, filtrate cools bottling and namely obtains oral liquid.
embodiment 3a kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from (getting 20g for every part): 16 parts, Radix Glycyrrhizae, Os Draconis 5 parts, Radix Ampelopsis 20 parts, Cortex Mori 13 parts, pears 23 parts, Radix Panacis Quinquefolii 33 parts, Fructus Trichosanthis 31 parts, Herba Asari 13.5 parts, Radix Raphani 9.5 parts, Rhizoma Imperatae 23.5 parts, Semen Maydis 13 parts, fevervine 8 parts, Folium Eriobotryae 4 parts, Radix Platycodonis 10 parts.
Above-mentioned dispelling coughs the preparation method of the drink that reduces phlegm, and step is:
(1) by pears and Radix Raphani peeling, clean 3 times, cut into slices, be placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 70 mesh sieves stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, steam 3 minutes after water boils, place 45 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, steam 2 minutes after water boils, stewing after 13 minutes, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, steam 5 minutes after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) be placed in large iron pan by Semen Maydis, add the warm water of Semen Maydis weight 33 times, little fire decocts to boiling, turns big fire decoct 2 minutes until boiling after 25 minutes, stewing 23 minutes, filter, Semen Maydis was placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing 2-4 hour is wrapped with preservative film, step (4) gained filtrate is heated to 30-40 DEG C, put into the crude drug of good seal, stir while decoct 3-7 minute, filter, filtrate cools bottling and namely obtains oral liquid.
embodiment 4a kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from (getting 15g for every part): 19 parts, Radix Glycyrrhizae, Os Draconis 7 parts, Radix Ampelopsis 22 parts, Cortex Mori 18 parts, pears 28 parts, Radix Panacis Quinquefolii 38 parts, Fructus Trichosanthis 34 parts, Herba Asari 14.5 parts, Radix Raphani 10.5 parts, Rhizoma Imperatae 24.5 parts, Semen Maydis 18 parts, fevervine 13 parts, Folium Eriobotryae 7 parts, Radix Platycodonis 12 parts.
Above-mentioned dispelling coughs the preparation method of the drink that reduces phlegm, and step is:
(1) by pears and Radix Raphani peeling, clean 5 times, cut into slices, be placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 90 mesh sieves stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, steam 5 minutes after water boils, place 55 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, 1-5 minute is steamed after water boils, stewing after 18 minutes, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, steam 7 minutes after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) be placed in large iron pan by Semen Maydis, add the warm water of Semen Maydis weight 38 times, little fire decocts to boiling, turns big fire decoct 4 minutes until boiling after 35 minutes, stewing 28 minutes, filter, Semen Maydis was placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing is wrapped 3.5 hours with preservative film, step (4) gained filtrate is heated to 38 DEG C, put into the crude drug of good seal, stir while decoct 6 minutes, filter, filtrate cools bottling and namely obtains oral liquid.
embodiment 5a kind ofly treat dispelling of chronic bronchitis and cough the drink that reduces phlegm, take off the primary raw material stating weight proportion and be prepared from (getting 30g for every part): 17.5 parts, Radix Glycyrrhizae, Os Draconis 6 parts, Radix Ampelopsis 21 parts, Cortex Mori 15 parts, pears 25 parts, Radix Panacis Quinquefolii 35 parts, Fructus Trichosanthis 32.5 parts, Herba Asari 14 parts, Radix Raphani 10 parts, Rhizoma Imperatae 24 parts, Semen Maydis 15 parts, fevervine 11 parts, Folium Eriobotryae 5.5 parts, Radix Platycodonis 11 parts.
(1) by pears and Radix Raphani peeling, clean 4 times, cut into slices, be placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 80 mesh sieves stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, steam 4 minutes after water boils, place 50 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, steam 3 minutes after water boils, stewing after 15 minutes, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, steam 5 minutes after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) be placed in large iron pan by Semen Maydis, add the warm water of Semen Maydis weight 35 times, little fire decocts to boiling, turns big fire decoct 3 minutes until boiling after 30 minutes, stewing 25 minutes, filter, Semen Maydis was placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing is wrapped 3 hours with preservative film, step (4) gained filtrate is heated to 35 DEG C, put into the crude drug of good seal, stir while decoct 5 minutes, filter, filtrate cools bottling and namely obtains oral liquid.
test example 1the clinical practice of the drink that reduces phlegm is coughed in dispelling of embodiment 5 gained treatment chronic bronchitis: screen 200 routine patients in 4 hospitals, oldest 65 years old, minimal ages 45 years old, 55 years old mean age, before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups, experimental group and matched group at random, experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine.
Using method is: gained is dispelled and coughed the drink that reduces phlegm, and take after 1 hour after the meal three, with warm water delivery service, each 5-10ml 7 days is a course for the treatment of.
Curative effect situation criterion: cure: after taking and using this product, malaise symptoms has clear improvement, and pain disappears substantially; Effective: after taking and using this product, malaise symptoms makes moderate progress, and pain alleviates to some extent; Invalid: after taking and using this product, malaise symptoms is unchanged.Result is as shown in table 1-2.
Table 1
Therapeutic effect: take and use the present invention to dispel and cough the drink effective percentage 98% that reduces phlegm, exceed 23% than matched group.Successful is better than matched group.
Table 2:
Prove through clinical trial, take the present invention dispel coughing reduce phlegm drink compared with taking the medicine of other treatment chronic bronchitis, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while treatment chronic bronchitis, can alleviate to cough by dispelling reduce phlegm, the symptom such as cough, asthma that chronic bronchitis is brought.Prove through clinical trial, the present invention dispels and coughing the drink effective percentage 98% that reduces phlegm, great majority dispel cough reduce phlegm, chronic bronchitis patient medication about 5 days, pain symptom has and obviously alleviates, and the present invention dispels and coughing the drink that reduces phlegm is the medicine for the treatment of chronic bronchitis safely and effectively.

Claims (10)

1. treat dispelling of chronic bronchitis and cough the drink that reduces phlegm for one kind, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Glycyrrhizae 15-20 part, Os Draconis 4-8 part, Radix Ampelopsis 18-25 part, Cortex Mori 10-20 part, pears 20-30 part, Radix Panacis Quinquefolii 30-40 part, Fructus Trichosanthis 15-30 part, Herba Asari 10-16 part, Radix Raphani 6-14 part, Rhizoma Imperatae 15-28 part, Semen Maydis 10-20 part, fevervine 5-15 part, Folium Eriobotryae 3-8 part, Radix Platycodonis 8-14 part.
2. dispelling for the treatment of chronic bronchitis according to claim 1 coughs the drink that reduces phlegm, and it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Glycyrrhizae 16-19 part, Os Draconis 5-7 part, Radix Ampelopsis 20-22 part, Cortex Mori 13-18 part, pears 23-28 part, Radix Panacis Quinquefolii 33-38 part, Fructus Trichosanthis 31-34 part, Herba Asari 13.5-14.5 part, Radix Raphani 9.5-10.5 part, Rhizoma Imperatae 23.5-24.5 part, Semen Maydis 13-18 part, fevervine 8-13 part, Folium Eriobotryae 4-7 part, Radix Platycodonis 10-12 part.
3. dispelling for the treatment of chronic bronchitis according to claim 1 coughs the drink that reduces phlegm, and it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: 17.5 parts, Radix Glycyrrhizae, Os Draconis 6 parts, Radix Ampelopsis 21 parts, Cortex Mori 15 parts, pears 25 parts, Radix Panacis Quinquefolii 35 parts, Fructus Trichosanthis 32.5 parts, Herba Asari 14 parts, Radix Raphani 10 parts, Rhizoma Imperatae 24 parts, Semen Maydis 15 parts, fevervine 11 parts, Folium Eriobotryae 5.5 parts, Radix Platycodonis 11 parts.
4. the preparation method of the drink that reduces phlegm is coughed in dispelling of the treatment chronic bronchitis according to any one of claim 1-3, it is characterized in that: step is as follows:
(1) by pears and Radix Raphani peeling, cleaning 2-6 time, cuts into slices, is placed in clean plate stand-by;
(2) Os Draconis are smashed, cross 60-100 mesh sieve stand-by;
(3) first by Radix Glycyrrhizae, Radix Ampelopsis, Cortex Mori, Radix Panacis Quinquefolii, Fructus Trichosanthis, Herba Asari, Rhizoma Imperatae, fevervine, Folium Eriobotryae and Radix Platycodonis are cleaned, again electric food warmer is cleaned, add clear water, food steamer is soaked, be placed on grill pan, first by Cortex Mori, Rhizoma Imperatae and fevervine are laid on food steamer, even with rice wine spray, 2-6 minute is steamed after water boils, place 40-60 DEG C, by Radix Glycyrrhizae, Radix Ampelopsis and Radix Panacis Quinquefolii are placed on steamed crude drug uniformly, even with rice vinegar spray, 1-5 minute is steamed after water boils, stewing after 10-20 minute, by Fructus Trichosanthis, Herba Asari, Folium Eriobotryae and Radix Platycodonis are placed on steamed crude drug, even with rice vinegar spray, 3-8 minute is steamed after water boils, air dry of drying in the air is done, grind to form smalls stand-by,
(4) Semen Maydis is placed in large iron pan, add Semen Maydis weight 30-40 warm water doubly, little fire decocts to boiling, turn big fire after 20-40 minute until boiling and decoct 2-4 minute, stewing 20-30 minute, filters, Semen Maydis is placed in close grenadine cloth, roll out moisture with rolling pin, Semen Maydis is fried to crisp, and it is stand-by to grind to form smalls;
(5) gained smalls in step (4) and step (1)-(3) gains are mixed, mix thoroughly with Mel, sealing 2-4 hour is wrapped with preservative film, step (4) gained filtrate is heated to 30-40 DEG C, put into the crude drug of good seal, stir while decoct 3-7 minute, filter, filtrate cools bottling and namely obtains oral liquid.
5. preparation method according to claim 4, is characterized in that: step (1) is by pears and Radix Raphani peeling, and cleaning 3-5 is all over (preferably by pears and Radix Raphani peeling, cleaning 4 times).
6. preparation method according to claim 4, is characterized in that: Os Draconis are smashed by step (2), crosses 70-90 mesh sieve stand-by (preferably smashed by Os Draconis, cross 80 mesh sieves stand-by).
7. preparation method according to claim 4, is characterized in that: step (3) steams 3-5 minute after water boils, and places 45-55 DEG C (preferably steam 4 minutes after water boils, place 50 DEG C).
8. preparation method according to claim 4, is characterized in that: steam 2-4 minute after step (3) water boils, stewing 13-18 minute (preferred water is steamed 3 minutes after boiling, stewing 15 minutes).
9. preparation method according to claim 4, it is characterized in that: step (4) adds Semen Maydis weight 33-38 warm water doubly, little fire decocts to boiling, turn big fire after 25-35 minute until boiling and decoct 2-4 minute, boil in a covered pot over a slow fire and (preferably add the warm water of Semen Maydis weight 35 times in 23-28 minute, little fire decocts to boiling, turns big fire decoct 3 minutes until boiling after 30 minutes, stewing 25 minutes).
10. preparation method according to claim 4, is characterized in that: step (5) is mixed thoroughly with Mel, wraps sealing 2.5-3.5 hour (preferably mix thoroughly with Mel, wrap sealing 3 hours with preservative film) with preservative film.
CN201510376142.2A 2015-07-01 2015-07-01 Cough expelling and phlegm reduction drink for treating chronic bronchitis and preparation method of cough expelling and phlegm reduction drink Pending CN104906434A (en)

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Application publication date: 20150916