CN103585510B - Oral liquid for treating cold in children - Google Patents

Oral liquid for treating cold in children Download PDF

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CN103585510B
CN103585510B CN201310634057.2A CN201310634057A CN103585510B CN 103585510 B CN103585510 B CN 103585510B CN 201310634057 A CN201310634057 A CN 201310634057A CN 103585510 B CN103585510 B CN 103585510B
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parts
portions
radix
oral liquid
herba
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CN103585510A (en
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郑美玲
孙秋香
郑晓瑛
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Abstract

The invention discloses an oral liquid for treating cold in children and belongs to the field of traditional Chinese medicines. Active components of the oral liquid comprise rostellularia procumbens, hispid arthraxon, Cucurbita moschata Duch, concretio silicea bambusae, Indigofera tinctoria Linn, corn silk, platycodon grandiflorum, cicada slough, tatarian aster root, carambola, lily, cortex phellodendri, carrot, root of kudzu vine, radix cynanchi atrati and sugarcane. The oral liquid has effects of clearing heat and removing toxins, expelling phlegm to arrest cough, and moistening lung and depressing qi, effectively treats children cold-caused fever, head swelling pain, cough and phlegm, and swelling and pain in throat, utilizes appropriate traditional Chinese medicines, has a low cost and no toxic or side effect, is suitable for children and can be clinically popularized.

Description

A kind of oral liquid for the treatment of infantile common cold
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of oral liquid for the treatment of infantile common cold.
Background technology
Infantile common cold and infantile acute upper respiratory infection, refer to the actute infection of more than throat, upper respiratory tract nasopharynx part, is also called for short " upper sense ".Infantile common cold, based on virus, can have mycoplasma and bacteriological infection in addition, and the whole year all can occur, more with winter-spring season, and at most, school age population reduces gradually in preschool period morbidity.
Slight infantile common cold only has sniffle, also can shed tears, tussicula or pharyngeal discomfort, can spontaneous recovery.If infect and relate to nasopharynx part, often have heating, pharyngalgia, tonsillitis, generate heat sustainable 2-3 days or about one week.Serious children flu body temperature can Da Gaore, falls sharply, the symptom such as sleep disorder with creeping chill, headache, general weakness, appetite, and because nasopharynx part secretions causes frequent cough.
Treatment at present for infantile common cold is mainly divided into western medical treatment and Chinese traditional treatment.Western medical treatment is mainly based on antibiotic, NSAID (non-steroidal anti-inflammatory drug), antihistaminic etc., and these drug side effectes are many, and what have even can cause serious untoward reaction, totally unfavorable to the Health restoration of child; The traditional Chinese medical science is in treatment infantile common cold, and mainly based on Chinese patent medicine, not only dosage is large, drug absorption slow, and patient compliance is poor, does not feel any better for a long time, and often delay treatment, aggravates disease.
For this reason, it is good that we are badly in need of a kind of therapeutic effect, and the dry flu of the Drug therapy children's had no side effect is to meet clinical needs.
Summary of the invention
The invention provides a kind of oral liquid for the treatment of infantile common cold, oral liquid of the present invention has effect of heat-clearing and toxic substances removing, expelling phlegm for arresting cough, lung moistening sending down the abnormal ascending QI, the symptoms such as the heating caused for infantile common cold, distending pain in the head, cough expectorant are glutinous, laryngopharynx swelling and pain have significant curative effect, the medicinal raw material compatibility chosen brings out the best in each other, with low cost and without any side effects, be applicable to child administration, clinic is extensively promoted.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat an oral liquid for infantile common cold, raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 61 ~ 91 parts of Herba Arthraxonis Hispidis 61 ~ 86 parts of Plantula cucurbitae moschataes 56 ~ 86 parts of Concretio Silicea Bambusaes 56 ~ 81 parts
Folium et Caulis Indigoferae Tinctoriae 51 ~ 81 parts of Stigma Maydis 46 ~ 76 parts of Radix Platycodoniss 46 ~ 76 portions of Periostracum Cicadaes 41 ~ 71 parts
Radix Asteris 41 ~ 71 portions of carambola 36 ~ 66 portions of Bulbus Liliies 31 ~ 61 portions of Cortex Phellodendris 31 ~ 56 parts
Radix Dauci Sativae 26 ~ 56 parts of Radix Puerariaes 21 ~ 51 portions of Radix Cynanchi Atratis 16 ~ 46 portions of Caulis Sacchari sinensis 11 ~ 41 parts.
Raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 66 ~ 86 parts of Herba Arthraxonis Hispidis 66 ~ 81 parts of Plantula cucurbitae moschataes 61 ~ 81 parts of Concretio Silicea Bambusaes 61 ~ 76 parts
Folium et Caulis Indigoferae Tinctoriae 56 ~ 76 parts of Stigma Maydis 51 ~ 71 parts of Radix Platycodoniss 51 ~ 71 portions of Periostracum Cicadaes 46 ~ 66 parts
Radix Asteris 46 ~ 66 portions of carambola 41 ~ 61 portions of Bulbus Liliies 36 ~ 56 portions of Cortex Phellodendris 36 ~ 51 parts
Radix Dauci Sativae 31 ~ 51 parts of Radix Puerariaes 26 ~ 46 portions of Radix Cynanchi Atratis 21 ~ 41 portions of Caulis Sacchari sinensis 16 ~ 36 parts.
Raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 71 ~ 81 parts of Herba Arthraxonis Hispidis 71 ~ 76 parts of Plantula cucurbitae moschataes 66 ~ 76 parts of Concretio Silicea Bambusaes 66 ~ 71 parts
Folium et Caulis Indigoferae Tinctoriae 61 ~ 71 parts of Stigma Maydis 56 ~ 66 parts of Radix Platycodoniss 56 ~ 66 portions of Periostracum Cicadaes 51 ~ 61 parts
Radix Asteris 51 ~ 61 portions of carambola 46 ~ 56 portions of Bulbus Liliies 41 ~ 51 portions of Cortex Phellodendris 41 ~ 46 parts
Radix Dauci Sativae 36 ~ 46 parts of Radix Puerariaes 31 ~ 41 portions of Radix Cynanchi Atratis 26 ~ 36 portions of Caulis Sacchari sinensis 21 ~ 31 parts.
Raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 76 parts of Herba Arthraxonis Hispidis 73 parts of Plantula cucurbitae moschataes 71 parts of Concretio Silicea Bambusaes 69 parts
Folium et Caulis Indigoferae Tinctoriae 66 parts of Stigma Maydis 61 parts of Radix Platycodoniss 61 portions of Periostracum Cicadaes 56 parts
Radix Asteris 56 portions of carambola 51 portions of Bulbus Liliies 46 portions of Cortex Phellodendris 43 parts
Radix Dauci Sativae 41 parts of Radix Puerariaes 36 portions of Radix Cynanchi Atratis 31 portions of Caulis Sacchari sinensis 26 parts.
Treat a preparation method for the oral liquid of infantile common cold, comprise following processing step:
(1) Herba Rostellulariae, Herba Arthraxonis Hispidi, Folium et Caulis Indigoferae Tinctoriae, Stigma Maydis, Radix Platycodonis, Radix Asteris, Bulbus Lilii and Radix Cynanchi Atrati are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) Plantula cucurbitae moschatae, carambola, Radix Dauci Sativae and Caulis Sacchari sinensis decontamination are cleaned, rub, filter impurity, stays juice for subsequent use;
(3) by Concretio Silicea Bambusae, Periostracum Cicadae and Radix Puerariae decontamination, after microwave drying, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(4) dry clean for Cortex Phellodendri decontamination, add the yellow wine moistening of 0.5 times amount, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, cross 180 order fine powders, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), juice and fine powder mixing, utilize modern advanced pharmacy science and technology, make oral liquid, be the oral liquid of described treatment infantile common cold.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Rostellulariae: mildly bitter flavor, cold in nature.Heat-clearing and toxic substances removing, inducing diuresis to remove edema, preventing the attack (or recurrence) of malaria.For cold, fever, malaria, laryngopharynx swelling and pain, infantile malnutrition, dysentery, enteritis, oedema due to nephritis, urinary system infection, chyluria, external is controlled carbuncle furuncle and is swollen, traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing, disappear stagnant dissipating blood stasis.Cure cold fever, laryngopharynx swelling and pain, infantile malnutrition, acute mastitis, hepatitis, traumatic injury.”
Herba Arthraxonis Hispidi: bitter in the mouth, property is put down.Heat clearing away sending down the abnormal ascending QI, relieving cough and asthma, removing toxic substances Eradicates rheumatism.Cure mainly hepatitis, chronic cough is panted, pharyngolaryngitis, stomatitis, rhinitis, lymphadenitis, mastitis.Scabies is controlled in external, skin pruritus, carbuncle furuncle.Be decocted in water for oral dose." property of medicine opinion " carries: " control all malignant boil.”
The Plantula cucurbitae moschatae: acrid in the mouth, slightly warm in nature; Return lung, spleen, stomach warp.Relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab.For Deficiency and coldness of spleen and stomach, loss of appetite, nausea and vomiting, vomiting due to fluid-retention, disorder of stomach-QI is vomitted, wind and cold productive cough, flu, fever with aversion to wind, nasal obstruction headache." Amplification on Materia Medica addendum " carries: " Xin Wen, all gently, sun also.Main cold headache, nasal obstruction, cough with dyspnea, the panacea of anti-nausea.Control cough sputum many users, this medicine can manage it the positive and gas therefore also of faling apart.”
Concretio Silicea Bambusae: sweet in the mouth, cold in nature; Enter the heart, liver, lung meridian.Clear heat and eliminate phlegm, cool heart arresting convulsion.Cure mainly calentura coma delirium, middle wind-phlegm fan in silence, twitch, epilepsy by infantile convulsion." Kaibao Bencao " carries: " main infantile convulsion sky hangs, and all wind heat are gone in relieving palpitation improving eyesight, treats incised wound hemostasis, nourishes the five internal organs.”
Folium et Caulis Indigoferae Tinctoriae: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly encephalitis B, parotitis, acute pharyngolaryngitis, lymphadenitis, conjunctival congestion, aphtha, carbuncle furuncle, erysipelas, scabies, worm venom, spit blood." the SHENGCAO property of medicine standby will " carries: " skin ulcer that disappears swells, eliminating blood stasis to promote regeneration of blood.Ye Zhi eyes covetously film, spits blood.”
Stigma Maydis: sweet in the mouth, property is put down; Return bladder, liver, gallbladder meridian.Inducing diuresis to remove edema, suppressing the hyperactive liver function of gallbladder promoting.Cure mainly edema, dribbling urination, jaundice, cholecystitis, cholelithiasis, hypertension, diabetes, galactostasis.
Radix Platycodonis: bitter in the mouth, pungent, property is put down; Return lung meridian.Lung qi dispersing eliminates the phlegm, sore-throat relieving evacuation of pus, benefiting qi and nourishing blood.Cure mainly cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery is suffered from abdominal pain, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, uroschesis." not Lu " carries: ", except cold and heat, migratory arthralgia, warming middle-JIAO rapid digestion of food, treats laryngopharynx pain for sharp the five internal organs the intestines and stomach, gas of enriching blood.”
Periostracum Cicadae: sweet in the mouth, cold in nature; Return lung, Liver Channel.Loose wind heat extraction, sore-throat relieving rash, nebula removing spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Radix Asteris: bitter in the mouth, pungent, warm in nature.Nourishing the lung to keep the adverse QI downward, preventing phlegm from forming and stopping coughing.Cure mainly deficiency of the lung chronic cough, consumptive lung disease lung abscess, coughs vomiting bloody pus, dysuria, and chronic cough is panted." book on Chinese herbal medicine is just " carries: " Radix Asteris, pungently can enter lung, bitter can sending down the abnormal ascending QI, therefore control cough with dyspnea, phlegm dyspnea, only excess of the lung gas is stopped up, or pathogenic fire punishment gold and the person that causes spitting bloody pus, be available it.”
Carambola: sweet in the mouth, acid, cold in nature; Enter lung, the heart, small intestine meridian.Clearing away heat and promoting production of body fluid, the therapeutic method to keep the adverse QI flowing downwards and in, inducing diuresis for treating stranguria syndrome, promoting the production of body fluid, it is tired to disappear, and relieving alcoholic intoxication is aid digestion.Cure mainly cough due to pathogenic wind-heat, thirsty agitation, has sore throat, stomatitis, toothache, hepatopathy, dysuria, calculosis, vitamin C deficiency, food poisonous wine poison." Luchuan book on Chinese herbal medicine " carries: " dredge stagnant, removing toxic substances, removing heat from blood.Control erosion of mucous membrane of the oral cavity, toothache.”
Bulbus Lilii: sweet in the mouth, micro-hardship, property is put down; Enter the heart, lung meridian.Heat-clearing and toxic substances removing, inducing diuresis to remove edema, tranquilizing by nourishing the heart, face nourishing antidebilitation.Be applicable to throat dry cough, hot the remnant pathogenic heat being not dispelled, the treatment of the diseases such as irritated insomnia." detailed outline is picked up any lost article from the road " carries: " clearing away phlegm fire, tonifying deficiency.”
Cortex Phellodendri: bitter in the mouth, cold in nature; Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus." medicineization justice " carries: " Cortex Phellodendri, to the marrow, be can capit ad calcem with pathogenic fire reducing, the thorough marrow of the skin that falls, invariably thoughtfully, specially rushes down the fire of kidney and bladder to bitter in the mouth.Lid kidney belongs to Han Shui, and water is ashamed at most to disappear, and dries up and exhausts then heating.If gas is person under umbilicus, YIN-fire also.”
Radix Dauci Sativae: sweet in the mouth, pungent, warm in nature, nontoxic.Strengthening the spleen to promote digestion, tonifying liver improving eyesight, heat-clearing and toxic substances removing, sending down the abnormal ascending QI cough-relieving.For infantile malnutrition, measles, nyctalopia, constipation, hypertension, gastrointestinal upset, chronic dysentery, full stifling is swollen." daily book on Chinese herbal medicine " carries: " the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, loose stomach is possessed stagnant.”
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Induce sweat and bring down a fever, rash of promoting the production of body fluid, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, hypertension, neck pain, thirstyly quenches one's thirst, and measles without adequate eruption, hematodiarrhoea is had loose bowels.Compendium of Material Medica is carried: " Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling." modern medicine study shows, the isoflavonoid puerarin in Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Radix Cynanchi Atrati: bitter in the mouth, salty, cold in nature, nontoxic; Return stomach, liver, kidney channel.Clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug." herbal classic " carries: " main sudden and violent apoplexy, fever of the body limb is full, before we notice it does not know people, mad puzzled pathogen, cold and heat ache, pyrexial malaria is washed, disease appearing at regular intervals.”
Caulis Sacchari sinensis: sweet in the mouth, puckery, property is put down, nontoxic; Attach to the lung and stomach meridians.Cure mainly the therapeutic method to keep the adverse QI flowing downwards and in, help temper, sharp large intestine, expectorant is quenched the thirst, irritable feverish sensation of chest and heart, vomiting regurgitation, chest and diaphragm." book on Chinese herbal medicine converge with speech " carries: " polyphagia is eaten for a long time, kindly sends out wet fire, is expectorant, swollen, the disease of vomitting, coughing." modern medicine study shows, containing materials such as abundant sugar, moisture and various vitamin, fat, protein, organic acid, calcium, ferrum in Caulis Sacchari sinensis, has remarkable result for raising body metabolism.
The present invention compared with prior art, has following beneficial effect:
Oral liquid of the present invention has effect of heat-clearing and toxic substances removing, expelling phlegm for arresting cough, lung moistening sending down the abnormal ascending QI, the symptoms such as the heating caused for infantile common cold, distending pain in the head, cough expectorant are glutinous, laryngopharynx swelling and pain have significant curative effect, the medicinal raw material compatibility chosen brings out the best in each other, with low cost and without any side effects, be applicable to child administration, clinic is extensively promoted.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Herba Rostellulariae 86g Herba Arthraxonis Hispidi 81g Plantula cucurbitae moschatae 81g Concretio Silicea Bambusae 76g
Folium et Caulis Indigoferae Tinctoriae 76g Stigma Maydis 71g Radix Platycodonis 71g Periostracum Cicadae 66g
Radix Asteris 66g carambola 61g Bulbus Lilii 56g Cortex Phellodendri 51g
Radix Dauci Sativae 51g Radix Puerariae 46g Radix Cynanchi Atrati 41g Caulis Sacchari sinensis 36g.
The preparation method of oral liquid of the present invention, comprises following processing step:
(1) Herba Rostellulariae, Herba Arthraxonis Hispidi, Folium et Caulis Indigoferae Tinctoriae, Stigma Maydis, Radix Platycodonis, Radix Asteris, Bulbus Lilii and Radix Cynanchi Atrati are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) Plantula cucurbitae moschatae, carambola, Radix Dauci Sativae and Caulis Sacchari sinensis decontamination are cleaned, rub, filter impurity, stays juice for subsequent use;
(3) by Concretio Silicea Bambusae, Periostracum Cicadae and Radix Puerariae decontamination, after microwave drying, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(4) dry clean for Cortex Phellodendri decontamination, add the yellow wine moistening of 0.5 times amount, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, cross 180 order fine powders, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), juice and fine powder mixing, utilize modern advanced pharmacy science and technology, make oral liquid, be the oral liquid of described treatment infantile common cold.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 15ml, after meal warm water delivery service; Within 3 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Embodiment 2
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Herba Rostellulariae 81g Herba Arthraxonis Hispidi 76g Plantula cucurbitae moschatae 76g Concretio Silicea Bambusae 71g
Folium et Caulis Indigoferae Tinctoriae 71g Stigma Maydis 66g Radix Platycodonis 66g Periostracum Cicadae 61g
Radix Asteris 61g carambola 56g Bulbus Lilii 51g Cortex Phellodendri 46g
Radix Dauci Sativae 46g Radix Puerariae 41g Radix Cynanchi Atrati 36g Caulis Sacchari sinensis 31g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Herba Rostellulariae 76g Herba Arthraxonis Hispidi 73g Plantula cucurbitae moschatae 71g Concretio Silicea Bambusae 69g
Folium et Caulis Indigoferae Tinctoriae 66g Stigma Maydis 61g Radix Platycodonis 61g Periostracum Cicadae 56g
Radix Asteris 56g carambola 51g Bulbus Lilii 46g Cortex Phellodendri 43g
Radix Dauci Sativae 41g Radix Puerariae 36g Radix Cynanchi Atrati 31g Caulis Sacchari sinensis 26g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Herba Rostellulariae 71g Herba Arthraxonis Hispidi 71g Plantula cucurbitae moschatae 66g Concretio Silicea Bambusae 66g
Folium et Caulis Indigoferae Tinctoriae 61g Stigma Maydis 56g Radix Platycodonis 56g Periostracum Cicadae 51g
Radix Asteris 51g carambola 46g Bulbus Lilii 41g Cortex Phellodendri 41g
Radix Dauci Sativae 36g Radix Puerariae 31g Radix Cynanchi Atrati 26g Caulis Sacchari sinensis 21g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Herba Rostellulariae 66g Herba Arthraxonis Hispidi 66g Plantula cucurbitae moschatae 61g Concretio Silicea Bambusae 61g
Folium et Caulis Indigoferae Tinctoriae 56g Stigma Maydis 51g Radix Platycodonis 51g Periostracum Cicadae 46g
Radix Asteris 46g carambola 41g Bulbus Lilii 36g Cortex Phellodendri 36g
Radix Dauci Sativae 31g Radix Puerariae 26g Radix Cynanchi Atrati 21g Caulis Sacchari sinensis 16g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the oral liquid for the treatment of infantile common cold, select the routine clinical observation of infantile common cold patient 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein boy 52 example, young girl 48 example, 1 ~ 12 years old age, 6.4 years old mean age, the shortest person of the course of disease 3 days, most elder 30 days, average 13 days; Matched group 100 example, wherein boy 51 example, young girl 49 example, 1 ~ 13 years old age, 6.7 years old mean age, the shortest person of the course of disease 4 days, most elder 32 days, average 14 days.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes oral liquid of the present invention, oral, every day 2 times, each 1 time sooner or later, each 15ml, after meal warm water delivery service; Within 3 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Matched group takes QIANGLI YINQIAO PIAN, oral, one time 3,3 times on the one 5 days is 1 course for the treatment of, 2 courses for the treatment of of the lighter, and severe one can be fully recovered 3 ~ 4 courses for the treatment of, and the person of being in a bad way is usually invalid,
3, efficacy determination:
(1) cure: after taking medicine, high heat, creeping chill, headache, general weakness, appetite fall sharply, the clinical symptom disappearance such as sleep disorder, passive protective physical fitness raising, healthy recovery.
(2) take a turn for the better: after taking medicine, above-mentioned symptom is alleviated to some extent, healthyly to recover to some extent.
(3) invalid: after taking medicine, symptom is without obvious change.
4, result:
Select in the treatment group of oral liquid of the present invention, cure 75 examples, take a turn for the better 24 examples, invalid 1 example, cure rate 75%, total effective rate 99%.
Cure 49 examples in matched group, take a turn for the better 24 examples, invalid 27 examples, cure rate 49%, total effective rate 73%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, the Qin, man, 3 years old, people from Datong.The symptoms such as infant is started after wind to occur snivel, gurgling with sputum, decreased food intake of receiving is few, family's long band its be hospitalized for treatment, used multiple Drug therapy, poor effect, invalid.To our hospital afterwards, start to take oral liquid of the present invention, take transference cure after 1 course for the treatment of, the state of an illness is fully recovered.
2, poplar, female, 5 years old, people from Baoding.Infant starts to occur the symptoms such as cough, nasal obstruction, snivel, gurgling with sputum, decreased food intake of receiving are few, uneasy sleeping at night after having a bath before 3 days, the head of a family hello its take the medicine such as QIANGLI YINQIAO PIAN, cough syrup all to no effect.Recommend to take oral liquid of the present invention through doctor, after taking 1 course for the treatment of, symptom disappears substantially, and after taking the 2nd course for the treatment of, symptom disappears completely, and the state of an illness is fully recovered.
3, Lee, man, 10 years old, people from Qingdao.Infants ' parents to find that child has a fever cough with symptoms such as nasal obstruction, sneezes a day morning, to our hospital, is diagnosed as seriousness and catches a cold.After taking 2 courses for the treatment of of oral liquid of the present invention, the symptoms such as nasal obstruction, cough, sneeze, fever all disappear, and flu returns to one's perfect health.
4, Lee, female, 12 years old, people from Shenyang, Liaoning.Patient causes high fever, goes out apogee sweating owing to suffering from infantile common cold, irritated thirsty, the symptom such as laryngopharynx swelling and pain, limb acid body is tired, with crossing many medicines equal inefficacies, rear admission, after taking 1 course for the treatment of of oral liquid of the present invention, cold symptoms disappears substantially, fully recovers after taking the 2nd course for the treatment of.

Claims (5)

1. treat an oral liquid for infantile common cold, it is characterized in that: raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 61 ~ 91 parts of Herba Arthraxonis Hispidis 61 ~ 86 parts of Plantula cucurbitae moschataes 56 ~ 86 parts of Concretio Silicea Bambusaes 56 ~ 81 parts
Folium et Caulis Indigoferae Tinctoriae 51 ~ 81 parts of Stigma Maydis 46 ~ 76 parts of Radix Platycodoniss 46 ~ 76 portions of Periostracum Cicadaes 41 ~ 71 parts
Radix Asteris 41 ~ 71 portions of carambola 36 ~ 66 portions of Bulbus Liliies 31 ~ 61 portions of Cortex Phellodendris 31 ~ 56 parts
Radix Dauci Sativae 26 ~ 56 parts of Radix Puerariaes 21 ~ 51 portions of Radix Cynanchi Atratis 16 ~ 46 portions of Caulis Sacchari sinensis 11 ~ 41 parts.
2. a kind of oral liquid for the treatment of infantile common cold according to claim 1, is characterized in that: raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 66 ~ 86 parts of Herba Arthraxonis Hispidis 66 ~ 81 parts of Plantula cucurbitae moschataes 61 ~ 81 parts of Concretio Silicea Bambusaes 61 ~ 76 parts
Folium et Caulis Indigoferae Tinctoriae 56 ~ 76 parts of Stigma Maydis 51 ~ 71 parts of Radix Platycodoniss 51 ~ 71 portions of Periostracum Cicadaes 46 ~ 66 parts
Radix Asteris 46 ~ 66 portions of carambola 41 ~ 61 portions of Bulbus Liliies 36 ~ 56 portions of Cortex Phellodendris 36 ~ 51 parts
Radix Dauci Sativae 31 ~ 51 parts of Radix Puerariaes 26 ~ 46 portions of Radix Cynanchi Atratis 21 ~ 41 portions of Caulis Sacchari sinensis 16 ~ 36 parts.
3. a kind of oral liquid for the treatment of infantile common cold according to claim 1, is characterized in that: raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 71 ~ 81 parts of Herba Arthraxonis Hispidis 71 ~ 76 parts of Plantula cucurbitae moschataes 66 ~ 76 parts of Concretio Silicea Bambusaes 66 ~ 71 parts
Folium et Caulis Indigoferae Tinctoriae 61 ~ 71 parts of Stigma Maydis 56 ~ 66 parts of Radix Platycodoniss 56 ~ 66 portions of Periostracum Cicadaes 51 ~ 61 parts
Radix Asteris 51 ~ 61 portions of carambola 46 ~ 56 portions of Bulbus Liliies 41 ~ 51 portions of Cortex Phellodendris 41 ~ 46 parts
Radix Dauci Sativae 36 ~ 46 parts of Radix Puerariaes 31 ~ 41 portions of Radix Cynanchi Atratis 26 ~ 36 portions of Caulis Sacchari sinensis 21 ~ 31 parts.
4. a kind of oral liquid for the treatment of infantile common cold according to claim 1, is characterized in that: raw material composition and the parts by weight of making described oral liquid effective ingredient are:
Herba Rostellulariae 76 parts of Herba Arthraxonis Hispidis 73 parts of Plantula cucurbitae moschataes 71 parts of Concretio Silicea Bambusaes 69 parts
Folium et Caulis Indigoferae Tinctoriae 66 parts of Stigma Maydis 61 parts of Radix Platycodoniss 61 portions of Periostracum Cicadaes 56 parts
Radix Asteris 56 portions of carambola 51 portions of Bulbus Liliies 46 portions of Cortex Phellodendris 43 parts
Radix Dauci Sativae 41 parts of Radix Puerariaes 36 portions of Radix Cynanchi Atratis 31 portions of Caulis Sacchari sinensis 26 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the oral liquid of infantile common cold, it is characterized in that: comprise following processing step:
(1) Herba Rostellulariae, Herba Arthraxonis Hispidi, Folium et Caulis Indigoferae Tinctoriae, Stigma Maydis, Radix Platycodonis, Radix Asteris, Bulbus Lilii and Radix Cynanchi Atrati are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) Plantula cucurbitae moschatae, carambola, Radix Dauci Sativae and Caulis Sacchari sinensis decontamination are cleaned, rub, filter impurity, stays juice for subsequent use;
(3) by Concretio Silicea Bambusae, Periostracum Cicadae and Radix Puerariae decontamination, after microwave drying, be placed in mortar and grind into powder, 200 object fine powders must be, for subsequent use;
(4) dry clean for Cortex Phellodendri decontamination, add the yellow wine moistening of 0.5 times amount, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, 180 object fine powders must be, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), juice and fine powder mixing, make oral liquid, be the oral liquid of described treatment infantile common cold.
CN201310634057.2A 2013-11-30 2013-11-30 Oral liquid for treating cold in children Expired - Fee Related CN103585510B (en)

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CN104906410A (en) * 2015-05-25 2015-09-16 安徽省怀远县华夏药械有限责任公司 Platycodon grandiflorus oral liquid
CN105617095A (en) * 2016-01-27 2016-06-01 朱德密 Oral liquid for acute upper respiratory infection in children and preparation method
CN109528941A (en) * 2018-12-14 2019-03-29 湖北荆江源制药股份有限公司 A kind of Chinese medicine for treating cold in children

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CN1899543A (en) * 2006-07-10 2007-01-24 左耀武 External plaster for treating child fever and preparing method
CN102671083A (en) * 2012-05-02 2012-09-19 李丽红 Infant cough-relieving and phlegm-reducing medicine

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Publication number Priority date Publication date Assignee Title
CN1899543A (en) * 2006-07-10 2007-01-24 左耀武 External plaster for treating child fever and preparing method
CN102671083A (en) * 2012-05-02 2012-09-19 李丽红 Infant cough-relieving and phlegm-reducing medicine

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