CN104903442A - 含用于纯化芳基硫酸酯酶a的方法 - Google Patents

含用于纯化芳基硫酸酯酶a的方法 Download PDF

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Publication number
CN104903442A
CN104903442A CN201480003307.5A CN201480003307A CN104903442A CN 104903442 A CN104903442 A CN 104903442A CN 201480003307 A CN201480003307 A CN 201480003307A CN 104903442 A CN104903442 A CN 104903442A
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CN
China
Prior art keywords
asa
purified
restructuring
ultrafiltration
column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480003307.5A
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English (en)
Chinese (zh)
Inventor
D·尼科尔斯
I·基农尼斯·加西亚
B·L·郑
M·H·蒋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Shire Human Genetics Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetics Therapies Inc filed Critical Shire Human Genetics Therapies Inc
Priority to CN202011058581.6A priority Critical patent/CN112126634A/zh
Priority to CN202510851520.1A priority patent/CN120665836A/zh
Priority to CN202510351647.7A priority patent/CN119979504A/zh
Publication of CN104903442A publication Critical patent/CN104903442A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/06—Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06001—Arylsulfatase (3.1.6.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/06—Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06008—Cerebroside-sulfatase (3.1.6.8)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201480003307.5A 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法 Pending CN104903442A (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN202011058581.6A CN112126634A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510851520.1A CN120665836A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510351647.7A CN119979504A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750693P 2013-01-09 2013-01-09
US61/750,693 2013-01-09
PCT/US2014/010856 WO2014110246A1 (en) 2013-01-09 2014-01-09 Methods for purification of arylsulfatase a

Related Child Applications (3)

Application Number Title Priority Date Filing Date
CN202510351647.7A Division CN119979504A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510851520.1A Division CN120665836A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202011058581.6A Division CN112126634A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法

Publications (1)

Publication Number Publication Date
CN104903442A true CN104903442A (zh) 2015-09-09

Family

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Family Applications (4)

Application Number Title Priority Date Filing Date
CN201480003307.5A Pending CN104903442A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510351647.7A Pending CN119979504A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510851520.1A Pending CN120665836A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202011058581.6A Pending CN112126634A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN202510351647.7A Pending CN119979504A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202510851520.1A Pending CN120665836A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法
CN202011058581.6A Pending CN112126634A (zh) 2013-01-09 2014-01-09 含用于纯化芳基硫酸酯酶a的方法

Country Status (12)

Country Link
US (3) US11407984B2 (https=)
EP (1) EP2943568B1 (https=)
JP (5) JP6427502B2 (https=)
CN (4) CN104903442A (https=)
AU (3) AU2014205441B2 (https=)
BR (1) BR112015015948B1 (https=)
CA (1) CA2896979C (https=)
EA (1) EA030551B1 (https=)
ES (1) ES2768261T3 (https=)
HK (1) HK1214622A1 (https=)
MX (2) MX372711B (https=)
WO (1) WO2014110246A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110632052A (zh) * 2019-10-25 2019-12-31 山西师范大学 土壤芳基硫酸酯酶活性的荧光光谱检测法
CN112082832A (zh) * 2019-06-12 2020-12-15 华南理工大学 一种保存城市污水中硫酸酯结合体和葡萄糖苷醛酸结合体的方法
CN112703010A (zh) * 2018-02-02 2021-04-23 恩真万特诊疗公司 用于治疗法伯病的方法
CN112759643A (zh) * 2021-03-17 2021-05-07 华兰生物工程股份有限公司 一种血清白蛋白的脱脂方法

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ES2625511T3 (es) * 2011-07-08 2017-07-19 Shire Human Genetic Therapies, Inc. Métodos para la purificación de arylsulfatasa A
AU2014205441B2 (en) 2013-01-09 2019-12-12 Takeda Pharmaceutical Company Limited Methods for purification of arylsulfatase A
EP3236772A4 (en) * 2014-12-22 2018-10-17 Alexion Pharmaceuticals, Inc. Methods of purifying recombinant proteins
EP3337819B1 (en) * 2015-08-20 2024-02-21 F. Hoffmann-La Roche AG Method of purifying for producing recombinant polypeptides using fkpa
CA3015685A1 (en) * 2016-03-16 2017-09-21 Phoenix Tissue Repair, Inc. Methods of purifying collagen 7
US11584777B2 (en) 2017-08-31 2023-02-21 Green Cross Corporation Method for purifying a sulfatase protein
WO2019126376A1 (en) * 2017-12-19 2019-06-27 Shire Human Genetic Therapies, Inc. Purified arylsulfatase a and compositons thereof
KR102791798B1 (ko) * 2018-04-12 2025-04-07 암젠 인크 안정한 단백질 조성물의 제조 방법
KR102286892B1 (ko) * 2019-07-08 2021-08-06 삼천당제약주식회사 안과용 단백질 제제의 정제방법
CN115066266A (zh) * 2019-12-12 2022-09-16 伊莱利利公司 用环保洗涤剂灭活病毒的方法
CN116693659B (zh) * 2023-07-11 2025-03-28 浙江大学 一种分离重组人血白蛋白的两步混合模式层析方法

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112703010A (zh) * 2018-02-02 2021-04-23 恩真万特诊疗公司 用于治疗法伯病的方法
CN112082832A (zh) * 2019-06-12 2020-12-15 华南理工大学 一种保存城市污水中硫酸酯结合体和葡萄糖苷醛酸结合体的方法
CN112082832B (zh) * 2019-06-12 2022-03-29 华南理工大学 一种保存城市污水中硫酸酯结合体和葡萄糖苷醛酸结合体的方法
CN110632052A (zh) * 2019-10-25 2019-12-31 山西师范大学 土壤芳基硫酸酯酶活性的荧光光谱检测法
CN112759643A (zh) * 2021-03-17 2021-05-07 华兰生物工程股份有限公司 一种血清白蛋白的脱脂方法

Also Published As

Publication number Publication date
AU2022221475B2 (en) 2025-05-22
US11407984B2 (en) 2022-08-09
JP2016504040A (ja) 2016-02-12
JP2018171067A (ja) 2018-11-08
CA2896979C (en) 2023-05-02
HK1216429A1 (en) 2016-11-11
MX372711B (es) 2020-04-21
JP2024001160A (ja) 2024-01-09
BR112015015948A2 (https=) 2017-08-15
AU2020201079A1 (en) 2020-03-05
HK1214622A1 (zh) 2016-07-29
EP2943568B1 (en) 2019-11-20
MX2015008875A (es) 2015-10-22
WO2014110246A1 (en) 2014-07-17
EA030551B1 (ru) 2018-08-31
US20230235303A1 (en) 2023-07-27
AU2022221475A1 (en) 2022-09-22
JP7663649B2 (ja) 2025-04-16
CN120665836A (zh) 2025-09-19
US12319940B2 (en) 2025-06-03
CN112126634A (zh) 2020-12-25
BR112015015948B1 (pt) 2022-05-17
AU2014205441A1 (en) 2015-06-25
EP2943568A1 (en) 2015-11-18
JP2020015750A (ja) 2020-01-30
AU2020201079B2 (en) 2022-05-26
EA201590826A1 (ru) 2015-11-30
JP7407161B2 (ja) 2023-12-28
JP2022023225A (ja) 2022-02-07
US11884945B2 (en) 2024-01-30
JP6427502B2 (ja) 2018-11-21
CN119979504A (zh) 2025-05-13
US20150353904A1 (en) 2015-12-10
US20240392268A1 (en) 2024-11-28
AU2014205441B2 (en) 2019-12-12
CA2896979A1 (en) 2014-07-17
ES2768261T3 (es) 2020-06-22
MX2020003798A (es) 2020-08-03

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