CN104888055A - Traditional Chinese medicine composition for treating eczema and preparation method - Google Patents
Traditional Chinese medicine composition for treating eczema and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating eczema and a preparation method. The composition is prepared from the following main raw materials in parts by weight: 10-15 parts of radix paeoniae rubra, 7-12 parts of bark of oroxylum indicum, 6-11 parts of white muscardine silkworm, 8-13 parts of lindera glauca leaves, 10-14 parts of dodonaea viscose leaves, 8-16 parts of murraya tetramera Huang, 12-17 parts of hibiscus mutabilis, 10-16 parts of scabrid smallhooked hedyotis herb, 8-14 parts of tribulus terrester, 10-13 parts of bark of chinese catalpa, 6-12 parts of croton lachnocarpus Benth, 9-16 parts of alternanthera sessilis, 11-15 parts of Chinese mahonia stem, 7-14 parts of rhizoma smilacis glabrae and 9-13 parts of veined rabdosia. The traditional Chinese medicine composition is high in safety, free of toxic or side effects and remarkable in curative effect, and can effectively adjust and recover the immunity of the organisms, improve immunity, decrease the sensibility of the organisms to the outside world, thoroughly eliminate the eczema cause, and effectively prevent the relapse of eczema.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and method for making for the treatment of eczema.
Background technology
Eczema is a kind of scytitis reaction of the acute pruritus caused by multiple internal and external factor.Divide acute, subacute, chronic three phases.Acute stage, tool oozed out tendency, and chronic phase then infiltrates, plumpness.Some patient directly translates into chronic eczema.Skin lesion has the features such as pleomorphism, symmetry, pruritus and easy recurrent exerbation.Eczematosis, because of complexity, is often internal and external reasons interaction result.Endogenous cause of ill is as chronic digestive system disease, psychentonia, insomnia, overtired, emotion changes, endocrine disturbance, infection, dysbolism etc., and exopathogenic factor such as living environment, climate change, food etc. all can affect the generation of eczema.Environmental stimuli as daylight, cold, drying, sweltering heat, hot water is scalded and various animal skin, plant, cosmetics, soap, staple fibre etc. all can bring out.It is a kind of delayed allergy that the complicated inside and outside factor causes.Clinical manifestation: be 1. divided into acute, subacute, chronic three phases by skin lesion performance.(1) acute eczema.Skin lesion is just the pimple of most intensive foxtail millet grain size, papulovesicle or phlysis, and substrate flushing, merges in flakes gradually, and owing to scratching, pimple, papulovesicle or vesicle top are oozed out and little rotten to the corn face in obvious point-like after scratching, blur margin.As secondary infection, inflammation is more obvious, can form pustule, pus crusts, folliculitis, furuncle etc.Conscious violent pruritus.After being apt to occur in women's head-ornaments, ear, distal limbs, scrotum, crissum etc., multipair title is issued.
(2) subacute eczema.After acute eczema inflammation alleviates, skin lesion based on little pimple, incrustation and squama, rarely seen a small amount of papulovesicle and erosion.Still have violent pruritus.(3) chronic eczema.Often because acute, subacute eczema recurrent exerbation more do not transfer chronic eczema to; Also can start to be chronic eczema.Show as illing skin to thicken, infiltrate, brownish red or pigmentation, rough surface, covers squama, or forms a scab because scratching.Conscious acute pruritus.Be common in the places such as shank, hands, foot, fossa cubitalis, popliteal nest, pudendum, anus.The course of disease is indefinite, easily recurs, and does not prolongedly heal.2., according to the scope that skin lesion involves, be divided into limitation eczema and the large class of universal eczema two.(1) limitation eczema.Occur over just specific part, namely can name, as hand eczema, pudendum eczema, eczema scrotum, ear eczema, breast eczema, anal eczema, legs eczema etc. at position.(2) universal eczema skin lesion is many, general or distribute in the multiple position of whole body.As coin eczema, autosensitization dermatitis, weary fat eczema.
Application publication number CN 103948733 A(application number 201410198245.X) Chinese patent literature disclose a kind of Chinese medicine for the treatment of eczema, be made up of the raw material of following weight portion: Fructus Forsythiae 6-9 part, Flos Lonicerae 10-15 part, Herba Schizonepetae 5-10 part, Herba Menthae 2-8 part, Radix Saposhnikoviae 10-15 part, Gypsum Fibrosum 10-20 part, Radix Glycyrrhizae 5-10 part, Periostracum Cicadae 5-10 part, Herba Houttuyniae 15-25 part, Fructus Gardeniae 5-10 part, Radix Salviae Miltiorrhizae 15-30 part, Radix Rehmanniae 15-25 part, Radix Angelicae Sinensis 6-12 part, Radix Sophorae Flavescentis 5-15 part.Application publication number CN 104398923 A(application number 201410432586.9) Chinese patent literature disclose a kind of Chinese medicine for the treatment of eczema, it is made up of the raw material of following weight proportioning: Radix Scutellariae 6 ~ 12, Cortex Phellodendri 10 ~ 18, Rhizoma Atractylodis 10 ~ 20, Radix Sophorae Flavescentis 12 ~ 23, Herba Plantaginis 15 ~ 25, Rhizoma Smilacis Glabrae 15 ~ 20, Semen Coicis 20 ~ 30, Caulis Akebiae 10 ~ 20, Herba Taraxaci 20 ~ 30, the Radix Rehmanniae 15 ~ 23, the Fructus Kochiae 8 ~ 14.Application publication number CN 104013867 A(application number 201410287998.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of eczema, it is mainly made up of following Chinese crude drug: Radix Sophorae Flavescentis, Cortex Dictamni, Radix Polygoni Multiflori, Indigo Naturalis, Zaocys, Cortex Phellodendri, the Radix Angelicae Dahuricae, Pollen Typhae, Herba Portulacae, Herba Taraxaci, fresh Rhizoma Phragmitis, Herba Houttuyniae, Semen Coicis, Semen Sinapis Albae, Herba Schizonepetae, Radix Saposhnikoviae, Semen Armeniacae Amarum, Radix Glycyrrhizae.
Treatment: eczematosis because of complexity, treatment still easy recurrent exerbation after taking a turn for the better, difficult radical cure.Because respectively there is feature at clinical form and position, therefore medication varies with each individual.1. general control principle.Find possibility inducement, as working environment, living habit, diet, hobby, thought mood etc., and with or without chronic lesion and internal organs disease.2. in, use therapy.Select antihistaminic antipruritic, two kinds coordinate or are used alternatingly if desired.Universal eczema can oral or injection glucocorticoid, but unsuitable life-time service.3. Topical therapy.Appropriate dosage forms and medicine is selected according to skin lesion situation.Acute eczema local physiological saline, 3% boric acid or 1:2000 ~ 1:10000 potassium permanganate solution rinse, soak, Calamine Lotion convergence, protection.Subacute, chronic eczema applies suitable glucocorticoid cream, burnt oil-like formulations or immunomodulator, as Tacrolimus paste, pimecrolimus ointment.Secondary infection person's added with antibiotic preparation.
For the treatment of eczema, a lot of patient can select western medical treatment.Western medical treatment eczema is based on hormone therapy for oral administration, and long-term taking can produce toxic and side effects, comparatively large to human body infringement, can only eliminate surface inflammation, can not solve morbidity root and the sensitinogen of eczema, be easy to recurrence.The therapy for treating improperly such as employing Western medicine drug, can cause serious harm.Such as, cause subacute or chronic dermatitis eczema, local is in lichen sample pathological changes.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine composition and method for making for the treatment of eczema.Safety of the present invention is high, have no side effect, evident in efficacy, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce body for the sensitivity in the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon.
Technical scheme of the present invention is:
Treat a Chinese medicine composition for eczema, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Paeoniae Rubra 10-15, Cortex Oroxyli 7-12, Bombyx Batryticatus (parched) 6-11, Folium Linderae Glaucae 8-13, clammy hopseedbush leaf 10-14, tetramerous jasminorange leaf 8-16, Hibisci Mutabilis 12-17, Herba Hedyotis scabridae 10-16, Fructus Tribuli 8-14, Cortex catalpae ovatae radicis 10-13, Folium Crotonis Laghnocarpi 6-12, Herba Alternantherae sessilis 9-16, Caulis Mahoniae 11-15, Rhizoma Smilacis Glabrae 7-14, Herba Rabdosiae Nervosae 9-13.
Treat a Chinese medicine composition for eczema, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Paeoniae Rubra 11-13, Cortex Oroxyli 8-10, Bombyx Batryticatus (parched) 7-10, Folium Linderae Glaucae 9-12, clammy hopseedbush leaf 11-13, tetramerous jasminorange leaf 10-14, Hibisci Mutabilis 13-15, Herba Hedyotis scabridae 12-15, Fructus Tribuli 9-13, Cortex catalpae ovatae radicis 11-12, Folium Crotonis Laghnocarpi 8-10, Herba Alternantherae sessilis 11-14, Caulis Mahoniae 12-14, Rhizoma Smilacis Glabrae 9-13, Herba Rabdosiae Nervosae 10-12.
Treat a Chinese medicine composition for eczema, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Paeoniae Rubra 12, Cortex Oroxyli 9, Bombyx Batryticatus (parched) 8, Folium Linderae Glaucae 10, clammy hopseedbush leaf 12, tetramerous jasminorange leaf 12, wooden cottonrose hibiscus 14, Herba Hedyotis scabridae 13, Fructus Tribuli 11, Cortex catalpae ovatae radicis 11.5, Folium Crotonis Laghnocarpi 9, Herba Alternantherae sessilis 13, Caulis Mahoniae 13, Rhizoma Smilacis Glabrae 12, Herba Rabdosiae Nervosae 11.
Present invention also offers the preparation method Chinese medicine composition of aforementioned therapies eczema being made pharmaceutically acceptable powder, pill, granule and capsule.
The preparation method of described powder is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. eight sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 11 taste crude drug gross weights) of 11 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. eight sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The preparation method of described pill is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. six sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 11 taste crude drug gross weights) of 11 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. six sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.5g of every ball, to obtain final product.
The preparation method of described granule is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 11 taste crude drug gross weights) of 11 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.6-1.1 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, be ground into granule again, obtain final product.
The preparation method of described capsule is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 11 taste crude drug gross weights) of 11 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.6-1.1 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.34g, to obtain final product.
Chinese medicine composition scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, safety high, have no side effect, evident in efficacy;
2, there is the effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, spleen invigorating dehumidifying, antipruritic pain relieving, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce the sensitivity of body for the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon;
3, medicine source is easy to get, and cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicine composition for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 450g): Radix Paeoniae Rubra 10 parts, Cortex Oroxyli 7 parts, Bombyx Batryticatus (parched) 6 parts, Folium Linderae Glaucae 8 parts, clammy hopseedbush leaf 10 parts, tetramerous jasminorange leaf 8 parts, Hibisci Mutabilis 12 parts, Herba Hedyotis scabridae 10 parts, Fructus Tribuli 8 parts, Cortex catalpae ovatae radicis 10 parts, Folium Crotonis Laghnocarpi 6 parts, Herba Alternantherae sessilis 9 parts, Caulis Mahoniae 11 parts, Rhizoma Smilacis Glabrae 7 parts, Herba Rabdosiae Nervosae 9 parts.
The preparation method of the Chinese medicine composition composition powders of above-mentioned treatment eczema is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. eight sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-and boil 12 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be 40% soak with ethanol 1 hour, the amount of ethanol is 6 times of 11 taste crude drug gross weights, 60 DEG C of heating extraction 2.8 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.30, drying under reduced pressure, be ground into fine powder, cross No. eight sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The instructions of taking of the Chinese medicine composition composition powders of gained treatment eczema of the present invention is: oral, one day twice, each 5g, boiled water was taken after mixing it with water.
embodiment 2treat a Chinese medicine composition for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 450g): Radix Paeoniae Rubra 15 parts, Cortex Oroxyli 12 parts, Bombyx Batryticatus (parched) 11 parts, Folium Linderae Glaucae 13 parts, clammy hopseedbush leaf 14 parts, tetramerous jasminorange leaf 16 parts, Hibisci Mutabilis 17 parts, Herba Hedyotis scabridae 16 parts, Fructus Tribuli 14 parts, Cortex catalpae ovatae radicis 13 parts, Folium Crotonis Laghnocarpi 12 parts, Herba Alternantherae sessilis 16 parts, Caulis Mahoniae 15 parts, Rhizoma Smilacis Glabrae 14 parts, Herba Rabdosiae Nervosae 13 parts.
The preparation method of the Chinese medicine composition pill of above-mentioned treatment eczema is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. six sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-and boil 15 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be 60% soak with ethanol 1 hour, the amount of ethanol is 7.6 times of 11 taste crude drug gross weights, 60 DEG C of heating extraction 4 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.32, drying under reduced pressure, be ground into fine powder, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.5g of every ball, to obtain final product.
model case one:lu XX, female, 39 years old.Main suit: eczema more than 1 year.Before 1 year, there is intensive foxtail millet grain size pimple without obvious inducement in patient, acute pruritus.Be eczema to hospital diagnosis, once by Drug therapys such as hormones, but the state of an illness is more and more serious.On March 10th, 2010 examines.Examine after seeing patient's women's head-ornaments, ear and have pimple, substrate flushing, merge in flakes, ooze out in obvious point-like and little rotten to the corn face, blur margin, acute pruritus.Be diagnosed as eczema.Take the Chinese medicine composition pill of the present embodiment gained treatment eczema, three times on the one, each 6 balls, warm water takes.Take 5 days, pruritus obviously alleviates, and pimple disappears more than half.Continue to take 5 days, all diseases disappear, and cure.Follow up a case by regular visits to without recurrence.
embodiment 3treat a Chinese medicine composition for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 450g): Radix Paeoniae Rubra 11 parts, Cortex Oroxyli 8 parts, Bombyx Batryticatus (parched) 7 parts, Folium Linderae Glaucae 9 parts, clammy hopseedbush leaf 11 parts, tetramerous jasminorange leaf 10 parts, Hibisci Mutabilis 13 parts, Herba Hedyotis scabridae 12 parts, Fructus Tribuli 9 parts, Cortex catalpae ovatae radicis 11 parts, Folium Crotonis Laghnocarpi 8 parts, Herba Alternantherae sessilis 11 parts, Caulis Mahoniae 12 parts, Rhizoma Smilacis Glabrae 9 parts, Herba Rabdosiae Nervosae 10 parts.
The preparation method of the Chinese medicinal composition granules of above-mentioned treatment eczema is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-and boil 15 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be 60% soak with ethanol 1 hour, the amount of ethanol is 7.6 times of 11 taste crude drug gross weights, 60 DEG C of heating extraction 4 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.32, drying under reduced pressure, be ground into fine powder, cross No. five sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight, mixing, be pressed into thin slice, then be ground into granule, to obtain final product.
model case two:king XX, man, 62 years old.Main suit: eczema more than 6 years.Before 6 years, patient without reason face and two hands forearms occur that Semen phaseoli radiati size is dispersed in erythema, pimple, after expand gradually.Once arrived Duo Jia hospital to treat, and failed to cure always.Within 2011, JIUYUE is examined on the 7th.Examine and see that patient facial region and two hands forearms are abound with cerise erythema, pimple, without blister, edema is obvious, and pruritus is very acute, and burning sensation is obvious, thirsty, dry stool, pale tongue, white and thin fur, moderate pulse.Take the Chinese medicinal composition granules of the present embodiment gained treatment eczema, three times on the one, each 10g, boiled water is taken after mixing it with water.Take 5 days, skin lesion disappears half, and pruritus alleviates.Continue to take 5 days, skin lesion disappears completely, and all diseases disappear.Follow-up observation is not recurred.
embodiment 4treat a Chinese medicine composition for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 450g): Radix Paeoniae Rubra 13 parts, Cortex Oroxyli 10 parts, Bombyx Batryticatus (parched) 10 parts, Folium Linderae Glaucae 12 parts, clammy hopseedbush leaf 13 parts, tetramerous jasminorange leaf 14 parts, Hibisci Mutabilis 15 parts, Herba Hedyotis scabridae 15 parts, Fructus Tribuli 13 parts, Cortex catalpae ovatae radicis 12 parts, Folium Crotonis Laghnocarpi 10 parts, Herba Alternantherae sessilis 14 parts, Caulis Mahoniae 14 parts, Rhizoma Smilacis Glabrae 13 parts, Herba Rabdosiae Nervosae 12 parts.
The preparation method of the Chinese medicinal composition capsules agent of above-mentioned treatment eczema is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-and boil 15 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be 60% soak with ethanol 1 hour, the amount of ethanol is 7.6 times of 11 taste crude drug gross weights, 60 DEG C of heating extraction 4 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.32, drying under reduced pressure, be ground into fine powder, cross No. five sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight, mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.34g, to obtain final product.
model case three:normal XX, female, 44 years old.Main suit: eczema more than 2 years.Before 2 years, there is erythema, pimple without obvious inducement, and accompany pruritis in patient's arm, hands, neck position.Go to a doctor to nearby hospitals, be diagnosed as eczema.Once attempted the treatment of multiple method, the state of an illness is not clearly better.Under the introduction of friend, patient examined on June 11st, 2010.Examine see patient's arm, hands, neck position scatters red erythema, pimple, with pruritus, xerostomia red tongue, thready and rapid pulse.Be diagnosed as eczema.Take the Chinese medicinal composition capsules agent of the present embodiment gained treatment eczema, three times on the one, each 3, warm water takes.Take 4 days, only, skin lesion reduces half to pruritus.Continue to take 5 days, skin lesion disappears, all transference cures.Follow up a case by regular visits to and do not recur.
embodiment 5 oneplant the Chinese medicine composition for the treatment of eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 450g): Radix Paeoniae Rubra 12 parts, Cortex Oroxyli 9 parts, Bombyx Batryticatus (parched) 8 parts, Folium Linderae Glaucae 10 parts, clammy hopseedbush leaf 12 parts, tetramerous jasminorange leaf 12 parts, wooden cottonrose hibiscus 14 parts, Herba Hedyotis scabridae 13 parts, Fructus Tribuli 11 parts, Cortex catalpae ovatae radicis 11.5 parts, Folium Crotonis Laghnocarpi 9 parts, Herba Alternantherae sessilis 13 parts, Caulis Mahoniae 13 parts, Rhizoma Smilacis Glabrae 12 parts, Herba Rabdosiae Nervosae 11 parts.
The preparation method of the Chinese medicine composition composition powders of above-mentioned treatment eczema is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. eight sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-and boil 15 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be 60% soak with ethanol 1 hour, the amount of ethanol is 7.6 times of 11 taste crude drug gross weights, 60 DEG C of heating extraction 4 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.32, drying under reduced pressure, be ground into fine powder, cross No. eight sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Paeoniae Rubra: base is former: be the dry root of ranunculaceae plant Radix Paeoniae or river Radix Paeoniae Rubra.Nature and flavor: bitter, are slightly cold.Return Liver Channel.Function cures mainly: clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion tumor, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, traumatic injury, carbuncle skin infection.
Cortex Oroxyli: base is former: be the bark of Bignoniaceae plant oroxylum indicum.The property of medicine: mildly bitter flavor; Slightly cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis, jaundice eliminating, relieving sore throat and diminishing swelling.Main infectious jaundice hepatitis, laryngopharynx swelling and pain.
Bombyx Batryticatus: have another name called Bombyx Batryticatus, flying worm, Bombyx Batryticatus worm, the larva belonging to animal bombyx mori for Bombycidae silkworm infects muscardine and ossified Scorpio.The property of medicine: this product is slightly cylindrical, how bending shrinkage, surperficial lark, matter is hard and crisp, frangibility, acrid in the mouth, salty, and property is put down.Composition: Bombyx Batryticatus containing protein, oxamidic acid., and contains lysine, leucine, aspartic acid etc. 17 seed amino acid.According to modern pharmacological research find, this medical instrument have expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, convulsion, hypoglycemic effect, for apoplexy, migraine and general headache, laryngopharynx swelling and pain, rubella etc.Bombyx Batryticatus (parched) is the processed product of Bombyx Batryticatus.After Bombyx Batryticatus parched with bran, the power of dispelling wind to relieve the exterior syndrome slightly subtracts, and is longer than dissipating phlegm and resolving masses.And Bombyx Batryticatus is after parched with bran, the mycelia on polypide surface and secretions contribute to being removed, and the bad smell that raw meat is salty have also been obtained rectification, are convenient to pulverize, and are convenient to take.In addition, the allergic phenomena indivedual body constitution can also being avoided to take raw product Bombyx Batryticatus cause.
Folium Linderae Glaucae: base is former: be the leaf of canella Fructus Linderae Glaucae.The property of medicine: bitter; Pungent; Cold nature.Return bladder, Liver Channel.Function cures mainly: detoxification and sores, and wind-expelling pain-stopping is antipruritic, hemostasis.Main sore swollen toxin, rheumatic arthralgia, traumatic injury, traumatic hemorrhage, skin pruritus, snake bite and insect sting.
Clammy hopseedbush leaf: base is former: be the leaf of sapindaceous plant akeake.The property of medicine: mildly bitter flavor; Pungent; Property is put down.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Main stranguria, the difficulty in urination, skin pruritus, carbuncle furuncle, burn.
Tetramerous jasminorange leaf: base is former: be the Ye Hegen of Rutaceae Murraya plant tetramerous jasminorange leaf.The property of medicine: pungent, micro-hardship, tepor.Function cures mainly: expelling pathogenic wind from the body surface, promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis.For cold, fever, bronchitis, asthma, rheumatic numbness, bones and muscles pain, traumatic injury swelling and pain due to blood stasis, skin pruritus, eczema, venom, malaria, stomachache, edema etc.
Hibisci Mutabilis: base is former: be Malvaceae Hibiscus plant Hibisci Mutabilis, be used as medicine with flower (Flos Hibisci Mutabilis), leaf (Folium Hibisci Mutabilis) and root.The property of medicine: micro-pungent, cool.Function cures mainly: heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis.For cough due to lung-heat, menorrhagia, leucorrhea; Carbuncle furuncle is controlled in external, mastitis, lymphadenitis, parotitis, burn and scald, venom, traumatic injury.
Herba Hedyotis scabridae: base is former: be the herb of the coarse glochild Auricled Hedyotis Herb of dicotyledon medicine Maguireothamnus speciosus.The property of medicine: acrid in the mouth; Sweet; Micro-hardship; Property is put down.Return stomach warp.Function cures mainly: expelling wind and removing dampness, spleen invigorating removing food stagnancy.Cardinal teeth infantile malnutrition, infantile malnutrition, rheumatic arthritis, has loose bowels, dysentery, skin pruritus.
Fructus Tribuli: another name: Fructus Tribuli, Fructus Atriplicis Sibiricae, hard Fructus Tribuli, the dry mature fruit of zygophyllaceae plant Fructus Tribuli.The property of medicine: pungent, bitter, tepor, slightly poisonous.Return Liver Channel.Function cures mainly: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, and improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Cortex catalpae ovatae radicis: base is former: be the root bark of Bignoniaceae plant Chinese catalpa or the phloem of tree.The property of medicine: bitter in the mouth; Cold in nature.Return gallbladder, stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis, sending down the abnormal ascending QI emesis, killing parasites for relieving itching.Main jaundice due to damp-heat, the inverse vomiting of stomach, skin ulcer scabies, eczema, skin pruritus.
Folium Crotonis Laghnocarpi: base is former: be leaf, the root of euphorbia plant comospore Fructus Crotonis.The property of medicine: acrid in the mouth; Bitter; Warm in nature; Poisonous.GUIXIN, lung meridian.Function cures mainly: dispelling cold and removing dampness; Expelling wind and activating blood circulation.Main arthralgia due to cold-dampnes, abdominal pain due to blood stasis, puerperal paralysis, treating swelling and pain by traumatic injury, skin pruritus.
Herba Alternantherae sessilis: base is former: be the herb of amaranthaceous plant Alternanthera sessilis (L.) DC..The property of medicine: sweet, cold.GUIXIN, stomach, small intestine meridian.Function cures mainly: cool the blood dissipate blood stasis, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Main hemoptysis, spit blood, have blood in stool, jaundice due to damp-heat, dysentery, has loose bowels, gingival swelling and pain, laryngopharynx swelling and pain, acute appendicitis, acute mastitis, the cheek of itching, swollen ulcer drug, eczema, stranguria, traumatic injury, venom.
Caulis Mahoniae: base is former: be stem or the peel of stem of Berberidaceae plant Mahonia bealei (Fort.) Carr., mahonia fortuneiFedde.The property of medicine: bitter; Cold in nature.Return large intestine, kidney, lung meridian.Function cures mainly: heat clearing away, dampness, removing toxic substances.Main cough due to lung-heat, jaundice, has loose bowels, dysentery, conjunctival congestion and swelling pain, skin infection, eczema, scalds.
Rhizoma Smilacis Glabrae: base is former: be the rhizome of Liliaceae smilax plant smilacis glabra.Composition: rhizome is containing volatile oil: 49 kinds of compositions such as n-hexadecanoic methyl ester; Phenolic acids: 3-0-caffeoyl shikimic acid, ferulic acid; Steroidal saponin, flavonoid glycoside etc.The property of medicine: sweet, light, flat.Return liver,kidney,spleen, stomach warp.Function cures mainly: removing damp-heat, lets out turbid removing toxic substances, easing joint movement.Cure mainly syphilis, stranguria with turbid discharge, have loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism.
Herba Rabdosiae Nervosae: base is former: be the herb of labiate veined rabdosia herb.The property of medicine: taste is micro-pungent; Bitter; Cold in nature.Function cures mainly: dampness removing stomach function regulating, removing toxic substances sore.Main acute hepatitis, dyspepsia, impetigo, eczema, skin pruritus, burn and scald, venom.
test example 1the clinical practice of the Chinese medicine composition (embodiment 5) of gained of the present invention treatment eczema: in December, 2008 in February ,-2012, screens 292 routine eczema patients in 4 hospitals, wherein male 135 example, women 157 example, age 22-64 year, 37 years old mean age, the course of disease 4 months-8 years.Be divided into two groups at random, experimental group and matched group (often organizing 146 examples).Between two groups of patients, the aspect such as sex, age, the state of an illness and course of disease compares, and no significant difference (P > 0.05), has comparability.
Therapeutic Method: experimental group takes the Chinese medicine composition of gained of the present invention treatment eczema, and using method is: oral, one day twice, each 5g, and boiled water is taken after mixing it with water, and 7 days is a course for the treatment of.Matched group uses the medicine (as Momestasone furoate cream, Desloratadine dispersible tablet, five those quick capsules of dimension Radix Glycyrrhizae etc.) of conventional therapy eczema, within 7 days, is a course for the treatment of.Comparitive study is carried out after two groups of patients all treat two courses for the treatment of.
Curative effect situation criterion: cure: skin lesion disappears completely, subjective symptoms disappears; Effective: skin lesion disappears more than 70%, and subjective symptoms obviously alleviates; Take a turn for the better: skin lesion disappears more than 30%, and subjective symptoms alleviates; Invalid: skin lesion disappears less than 30% or unchanged, and pruritus is without obviously alleviating.Total effectively comprising cures and effective, and result is as shown in table 1.
Table 1: the Chinese medicine composition compliance test result of gained treatment eczema of the present invention
Efficacy analysis: after two groups of cases treat two courses for the treatment of, experimental group cures 87 examples, effective 57 examples, and take a turn for the better 2 examples, total effective rate 98.63%; Matched group cures 28 examples, effective 79 examples, and take a turn for the better 24 examples, invalid 15 examples, total effective rate 73.29%.The cure rate of experimental group and total effective rate are apparently higher than matched group.Test shows, the clinical efficacy of experimental group is obviously better than matched group.
The present invention is primary raw material medicine with Radix Paeoniae Rubra, Cortex Oroxyli, Bombyx Batryticatus (parched) and Folium Linderae Glaucae etc., makes the Chinese medicine composition for the treatment of eczema.Radix Paeoniae Rubra clearing away heat and cooling blood in side, eliminating stasis to stop pain.Cortex Oroxyli clearing away heat-damp and promoting diuresis, jaundice eliminating, relieving sore throat and diminishing swelling.Bombyx Batryticatus (parched) dissipating phlegm and resolving masses.Folium Linderae Glaucae detoxification and sores, wind-expelling pain-stopping, antipruritic, hemostasis.Clammy hopseedbush leaf clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Tetramerous jasminorange leaf expelling pathogenic wind from the body surface, promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis.Hibisci Mutabilis heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis.Herba Hedyotis scabridae expelling wind and removing dampness, spleen invigorating removing food stagnancy.Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Cortex catalpae ovatae radicis clearing away heat-damp and promoting diuresis, sending down the abnormal ascending QI emesis, killing parasites for relieving itching.Folium Crotonis Laghnocarpi dispelling cold and removing dampness; Expelling wind and activating blood circulation.Herba Alternantherae sessilis cool the blood dissipate blood stasis, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Caulis Mahoniae heat clearing away, dampness, removing toxic substances.Rhizoma Smilacis Glabrae removing damp-heat, lets out turbid removing toxic substances, easing joint movement.Herba Rabdosiae Nervosae dampness removing stomach function regulating, removing toxic substances sore.Many medicines share, and mutually coordinate, and play the effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, spleen invigorating dehumidifying, antipruritic pain relieving altogether, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce the sensitivity of body for the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat a Chinese medicine composition for eczema, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Paeoniae Rubra 10-15, Cortex Oroxyli 7-12, Bombyx Batryticatus (parched) 6-11, Folium Linderae Glaucae 8-13, clammy hopseedbush leaf 10-14, tetramerous jasminorange leaf 8-16, Hibisci Mutabilis 12-17, Herba Hedyotis scabridae 10-16, Fructus Tribuli 8-14, Cortex catalpae ovatae radicis 10-13, Folium Crotonis Laghnocarpi 6-12, Herba Alternantherae sessilis 9-16, Caulis Mahoniae 11-15, Rhizoma Smilacis Glabrae 7-14, Herba Rabdosiae Nervosae 9-13.
2. the Chinese medicine composition for the treatment of eczema as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Paeoniae Rubra 11-13, Cortex Oroxyli 8-10, Bombyx Batryticatus (parched) 7-10, Folium Linderae Glaucae 9-12, clammy hopseedbush leaf 11-13, tetramerous jasminorange leaf 10-14, Hibisci Mutabilis 13-15, Herba Hedyotis scabridae 12-15, Fructus Tribuli 9-13, Cortex catalpae ovatae radicis 11-12, Folium Crotonis Laghnocarpi 8-10, Herba Alternantherae sessilis 11-14, Caulis Mahoniae 12-14, Rhizoma Smilacis Glabrae 9-13, Herba Rabdosiae Nervosae 10-12.
3. the Chinese medicine composition for the treatment of eczema as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Paeoniae Rubra 12, Cortex Oroxyli 9, Bombyx Batryticatus (parched) 8, Folium Linderae Glaucae 10, clammy hopseedbush leaf 12, tetramerous jasminorange leaf 12, Hibisci Mutabilis 14, Herba Hedyotis scabridae 13, Fructus Tribuli 11, Cortex catalpae ovatae radicis 11.5, Folium Crotonis Laghnocarpi 9, Herba Alternantherae sessilis 13, Caulis Mahoniae 13, Rhizoma Smilacis Glabrae 12, Herba Rabdosiae Nervosae 11.
4. the Chinese medicine composition of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment eczema is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. eight sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 minute that boils, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times of 13 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour, extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. eight sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
5. the Chinese medicine composition of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment eczema is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. six sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 13 taste crude drug gross weights) of 13 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. six sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.5g of every ball, to obtain final product.
6. the Chinese medicine composition of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment eczema is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 13 taste crude drug gross weights) of 13 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.6-1.1 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, be ground into granule again, obtain final product.
7. the Chinese medicine composition of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment eczema is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Bombyx Batryticatus (parched) is ground into fine powder, crosses No. five sieves;
(2) Fructus Tribuli is put into boiling water, keep micro-12-18 of boiling minute (preferably keeping micro-boiling 15 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(3) by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be the soak with ethanol 1 hour soak with ethanol of 60% (by all the other the 13 taste crude drug volume fractions except Bombyx Batryticatus (parched) and Fructus Tribuli be preferably 1 hour) of 40%-75%, the amount of ethanol is 6-9 times (amount of preferred alcohol is 7.6 times of 13 taste crude drug gross weights) of 13 taste crude drug gross weights, 60 DEG C of heating extraction 2.8-4.5 hour (preferably 60 DEG C heating extraction 4 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.35, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.6-1.1 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 0.9 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, capsule is equipped with granule 0.34g, obtains final product by every.
8. the preparation method of the Chinese medicine composition composition powders for the treatment of eczema as claimed in claim 4, is characterized in that, keep micro-boiling 15 minutes in step (2).
9. the preparation method of the Chinese medicine composition composition powders for the treatment of eczema as claimed in claim 4, is characterized in that, in step (3), the amount of ethanol is 7.6 times of 13 taste crude drug gross weights.
10. the preparation method of the Chinese medicine composition composition powders for the treatment of eczema as claimed in claim 4, is characterized in that, 60 DEG C of heating extraction 4 hours in step (3).
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Address after: 744300 Gansu, Dingxi Anding District, No. 8, Yu Yuan Garden District, building 2-401, 1, Applicant after: Shang Xiaoxia Address before: Ying Shi Xi Jie, Huaiyin District of Ji'nan city of Shandong Province, No. 5 250000 Applicant before: Shang Xiaoxia |
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