CN104884627A - 具有小型启动子盒的逆转录病毒载体 - Google Patents

具有小型启动子盒的逆转录病毒载体 Download PDF

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Publication number
CN104884627A
CN104884627A CN201380067486.4A CN201380067486A CN104884627A CN 104884627 A CN104884627 A CN 104884627A CN 201380067486 A CN201380067486 A CN 201380067486A CN 104884627 A CN104884627 A CN 104884627A
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promoter
retrovirus
sequence
cells
pac3
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CN201380067486.4A
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Chinese (zh)
Inventor
海瑞·E·格鲁伯
道格拉斯·J·乔利
艾米·H·林
克里斯多弗·R·洛格
笠原典之
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Suoyuan Biomedical Usa Co ltd
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Tocagen Inc
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/10011—Retroviridae
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    • C12N2740/10011—Retroviridae
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
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    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04001—Cytosine deaminase (3.5.4.1)

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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201380067486.4A 2012-10-25 2013-10-24 具有小型启动子盒的逆转录病毒载体 Pending CN104884627A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261718610P 2012-10-25 2012-10-25
US61/718,610 2012-10-25
PCT/US2013/066709 WO2014066700A1 (en) 2012-10-25 2013-10-24 Retroviral vector with mini-promoter cassette

Publications (1)

Publication Number Publication Date
CN104884627A true CN104884627A (zh) 2015-09-02

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CN201380067486.4A Pending CN104884627A (zh) 2012-10-25 2013-10-24 具有小型启动子盒的逆转录病毒载体

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Country Link
US (1) US11065311B2 (https=)
EP (2) EP3623478A1 (https=)
JP (3) JP6419706B2 (https=)
CN (1) CN104884627A (https=)
ES (1) ES2786051T3 (https=)
WO (1) WO2014066700A1 (https=)

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CN108138201A (zh) * 2015-09-04 2018-06-08 托卡根公司 包含2a肽的重组载体
CN108291208A (zh) * 2015-11-24 2018-07-17 葛兰素史密斯克莱知识产权发展有限公司 用于产生逆转录病毒的稳定细胞系
CN108474003A (zh) * 2015-11-20 2018-08-31 俄勒冈健康与科学大学 包含微小rna识别元件的cmv载体
CN116334010A (zh) * 2023-05-30 2023-06-27 中义(北京)健康研究院 一种重组单纯疱疹病毒及其制备方法和应用

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KR20220061977A (ko) 2019-08-12 2022-05-13 퓨리노미아 바이오테크, 아이엔씨. Cd39 발현 세포의 adcc 표적화를 통해 t 세포 매개 면역 반응을 촉진 및 강화하기 위한 방법 및 조성물
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JP2023511717A (ja) * 2020-01-30 2023-03-22 パーデュー・リサーチ・ファウンデーション 治療用タンパク質のリガンド媒介性送達およびその使用
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WO2022234003A1 (en) 2021-05-07 2022-11-10 Avacta Life Sciences Limited Cd33 binding polypeptides with stefin a protein
TW202334196A (zh) 2021-10-07 2023-09-01 英商阿法克塔生命科學有限公司 Pd-l1結合多肽
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JP2025515486A (ja) 2022-04-29 2025-05-15 ピュリノミア バイオテック， インコーポレイテッド 好酸球駆動性疾患及び障害を治療するための方法及び組成物
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