CN104873700A - Medicament for treating vascular headache and limb numbness and preparation method thereof - Google Patents
Medicament for treating vascular headache and limb numbness and preparation method thereof Download PDFInfo
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- CN104873700A CN104873700A CN201510322662.5A CN201510322662A CN104873700A CN 104873700 A CN104873700 A CN 104873700A CN 201510322662 A CN201510322662 A CN 201510322662A CN 104873700 A CN104873700 A CN 104873700A
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Abstract
The invention discloses a medicament for treating vascular headache and limb numbness and a preparation method thereof. The medicament is mainly prepared from pseudo-ginseng, angelica, ground beetle, dragon blood, scorpion and centipede according to a certain weight ratio. The medicament has the functions of dispelling wind-evil, relieving convulsion, activating blood, removing stasis, dredging collaterals and nourishing blood, is used for treating vascular headache and limb numbness, has the advantages of quick response, good curative effect and no recurrence.
Description
Technical field
The present invention relates to and a kind ofly treat medicine of vascular headache and numb limbs and tense tendons and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Vascular headache is a type the most common in outpatient service headache patient, because cause the reason of this kind of headache all to come from blood vessel, therefore is referred to as vascular headache.Vascular headache is divided into constitutional and the large class of Secondary cases two.Because of the headache that head vasomotor dysfunction causes, be called constitutional vascular headache; There is the headache caused by clear and definite cerebrovascular disease, be called secondary headache.Pathologic numb limbs and tense tendons is many without obvious inducement, persistent period is longer, or recurrent exerbation, heavy when time is light, often with other symptoms, as the numbness of hands and feet that cerebral arteriosclerosis causes, can to increase with dizziness, headache, hypomnesis, visual deterioration, blood pressure or on the low side, the changes such as blood fat increases, and this numbness of hands and feet is half side, patient age is also bigger than normal; At present, because Western medicine cannot effectively treat vascular headache and numb limbs and tense tendons, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment vascular headache and numb limbs and tense tendons, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally successfully have found the medicine of effectively treatment vascular headache and numb limbs and tense tendons, thus completes the present invention.
Object of the present invention is just to provide the Chinese medicine composition of a kind of effective treatment vascular headache and numb limbs and tense tendons.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Radix Notoginseng, Radix Angelicae Sinensis, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, Scorpio, Scolopendra, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Mel medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus can effectively treat vascular headache and numb limbs and tense tendons.Wherein select Radix Notoginseng to be because its property sweet and slightly bitter taste, temperature, enters liver, stomach, large intestine channel, has hemostasis, dissipating blood stasis, detumescence, the function of analgesic therapy, control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia mass in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Eupolyphaga Seu Steleophaga is selected to be salty because of its nature and flavor, cold, slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea ， mass in the abdomen mass in the abdomen.Sanguis Draxonis is selected to be because its property sweet-salty, flat, enter the heart, Liver Channel, have dissipating blood stasis analgesic therapy, the function of hemostasia and promoting granulation, control traumatic injury and lose, ecchymoma due to internal injury, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Select Scorpio to be because its nature and flavor are salty pungent, flat, poisonous, enter meridian of Foot-JUE YIN, dispel the wind, relieving convulsion, dredging collateral, the function of removing toxic substances, control convulsion with spasms ， epilepsy, apoplexy, hemiplegia, deviation of the eye and mouth, migraine, rheumatic arthralgia, tetanus, tuberculous lymphadenitis, rubella skin ulcer swells.Select Scolopendra to be because its nature and flavor are pungent, temperature, poisonous, enter Liver Channel, dispel the wind, arresting convulsion, counteracting toxic substances, the function of eliminating stagnation, controls apoplexy ， Jing Epilepsy, tetanus, pertussis, Ji scrofula, tuberculosis ， mass in the abdomen tumor block, sore swollen toxin, and tinea corporis is bald in vain, anal fistula, scalds.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Select Mel to be that flat, enter lung, spleen, large intestine channel, have invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup because its nature and flavor are sweet, separate Aconitum Carmichaeli.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Radix Notoginseng 10-20 gram, Radix Angelicae Sinensis 10-15 gram, Eupolyphaga Seu Steleophaga 3-9 gram, Sanguis Draxonis 1-2 gram, Scorpio 5-8 gram, Scolopendra 5-10 gram, Rhizoma Chuanxiong 5-10 gram, Radix Angelicae Dahuricae 5-10 gram, Mel 20-30 gram;
Be preferably:
Radix Notoginseng 15 grams, Radix Angelicae Sinensis 13 grams, Eupolyphaga Seu Steleophaga 7 grams, Sanguis Draxonis 1.5 grams, Scorpio 8 grams, Scolopendra 8 grams, Rhizoma Chuanxiong 8 grams, the Radix Angelicae Dahuricae 8 grams, Mel 25 grams;
The preparation method of medicine of the present invention is as follows:
One, get the raw materials ready
1, Radix Notoginseng: pick clean impurity, smash to pieces, grinds or runs through rear section into powder and dry;
2, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
3, Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
4, Sanguis Draxonis: wipe dust away, knock fritter, in winter dryness weather, is placed on and makes dry in Calx altar, then take advantage of crisp grinding into powder;
5, Scorpio: clear water floats the matter that desalts, and dries, or low baking temperature roasting is used;
6, Scolopendra: wipe clean, removing cephalopodium, cuts off use;
7, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
8, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
9, Mel: get pure Mel, temper with slow fire, filters skimming;
Two, prepare
1, the Radix Notoginseng of described weight, Radix Angelicae Sinensis, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, Scorpio, Scolopendra, Rhizoma Chuanxiong, Radix Angelicae Dahuricae medicine are put into container, stir and grind to form fine powder;
2, Mel is refined into the tender honey of 110-115 DEG C;
3, stick together grinding for the spice of fine powder adds mixing system in Mel, then rubbing pill, every ball is containing pure medicine 1 gram.
Medicine of the present invention has and dispels the wind, and relieving convulsion, blood circulation promoting and blood stasis dispelling, the function that dredging collateral nourishes blood, is used for the treatment of vascular headache and numb limbs and tense tendons instant effect, good effect, does not recur.
In prescription, Radix Notoginseng has hemostasis, dissipating blood stasis, detumescence, and the function of analgesic therapy is monarch drug, and Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes the function of laxation, and Eupolyphaga Seu Steleophaga, Sanguis Draxonis have dissipating blood stasis analgesic therapy, and the function three taste medicine of hemostasia and promoting granulation is ministerial drug; Four Chinese medicine plays the effect of benefiting blood and regulating blood circulation, blood circulation promoting and blood stasis dispelling, expelling wind for relieving convulsion jointly, treatment vascular headache and numb limbs and tense tendons effect comprehensive, and can to effect a permanent cure for master with benefiting blood and regulating blood circulation, blood circulation promoting and blood stasis dispelling; Scorpio is dispeled the wind, relieving convulsion, dredging collateral, the function of removing toxic substances, and Scolopendra is dispeled the wind, arresting convulsion, counteracting toxic substances, the function of eliminating stagnation, and two taste medicines are adjuvant drug, and Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Mel dispel the wind, dampness, and detumescence, the function of pain relieving, cold expelling, for making medicine, can be taken stopgap measures with adjuvant drug.Said medicine is combined, makes it efficacy of drugs and produce synergism, thus effectively can treat the recurrence of vascular headache and numb limbs and tense tendons.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 0.15g/kg, and normal amount is 0.1g/kg, and administering mode is gastric infusion after thin up, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 58 examples for medical treatment.
2, diagnostic criteria
Vascular headache is divided into constitutional and the large class of Secondary cases two.Because of the headache that head vasomotor dysfunction causes, be called constitutional vascular headache; The headache having clear and definite cerebrovascular disease to cause, is called secondary headache.Its headache many in mild to moderate full headache, distending pain, also can show as occipitalia, forehead, two temples pain, require mental skill, exert oneself, movable punch head and change position time have a headache and increase the weight of, often with similar neurasthenia symptom.Also normal outbreak presents obvious blood vessel jumping pain, nausea and vomiting, has blurred vision before typical patient episode, and eye grows dim performance.
Pathologic numb limbs and tense tendons, persistent period is longer, or recurrent exerbation, heavy when time is light, often with other symptoms, as the numbness of hands and feet that cerebral arteriosclerosis causes, can to increase with dizziness, headache, hypomnesis, visual deterioration, blood pressure or on the low side, the changes such as blood fat increases, and this numbness of hands and feet is half side, patient age is also bigger than normal; The numbness that cervical spondylosis causes is Ipsilateral hands or upper limb numbness, companion's pain, limitation of activity; The numbness that peripheral polyneuritis causes is that acra symmetry is numb, companion's pain; Thromboangiitis also can cause toe-end or foot to send out cool, feel cold, and has an intense pain, pulsation of foot dorsal artery weakens or disappearance etc.
3, Therapeutic Method
Select above-mentioned pill to take to patient, each serving using 6 balls, every day takes night and morning, and within 7 days, is a course for the treatment of, takes 2-3 the course for the treatment of continuously.
4, efficacy assessment standard
Effective: vascular headache and numb limbs and tense tendons symptom are eliminated, recovery from illness, without recurring after observing half a year;
Take a turn for the better: vascular headache and numb limbs and tense tendons symptom alleviate, and the state of an illness is clearly better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy vascular headache patient 30 example of the present invention, effective 26 examples of result, obvious effective rate is 86.67%, and take a turn for the better 2 examples, and improvement rate is 6.66%, and invalid 2 examples, total effective rate is 93.33%.Treatment numb limbs and tense tendons patient 28 example, effective 24 examples of result, obvious effective rate is 85.71%, and take a turn for the better 3 examples, and improvement rate is 10.71%, and invalid 1 example, total effective rate is 96.42%.
Claims (3)
1. treat a medicine for vascular headache and numb limbs and tense tendons, it is characterized in that: it is made up of the crude drug in following weight range: Radix Notoginseng 10-20 gram, Radix Angelicae Sinensis 10-15 gram, Eupolyphaga Seu Steleophaga 3-9 gram, Sanguis Draxonis 1-2 gram, Scorpio 5-8 gram, Scolopendra 5-10 gram, Rhizoma Chuanxiong 5-10 gram, Radix Angelicae Dahuricae 5-10 gram, Mel 20-30 gram.
2. medicine according to claim 1, wherein the consumption of each raw material thing is: Radix Notoginseng 15 grams, Radix Angelicae Sinensis 13 grams, Eupolyphaga Seu Steleophaga 7 grams, Sanguis Draxonis 1.5 grams, Scorpio 8 grams, Scolopendra 8 grams, Rhizoma Chuanxiong 8 grams, the Radix Angelicae Dahuricae 8 grams, Mel 25 grams.
3. the preparation method of medicine according to claim 1 and 2, is characterized in that: it comprises the following steps:
One, get the raw materials ready
1, Radix Notoginseng: pick clean impurity, smash to pieces, grinds or runs through rear section into powder and dry;
2, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
3, Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
4, Sanguis Draxonis: wipe dust away, knock fritter, in winter dryness weather, is placed on and makes dry in Calx altar, then take advantage of crisp grinding into powder;
5, Scorpio: clear water floats the matter that desalts, and dries, or low baking temperature roasting is used;
6, Scolopendra: wipe clean, removing cephalopodium, cuts off use;
7, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
8, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
9, Mel: get pure Mel, temper with slow fire, filters skimming;
Two, prepare
1, the Radix Notoginseng of described weight, Radix Angelicae Sinensis, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, Scorpio, Scolopendra, Rhizoma Chuanxiong, Radix Angelicae Dahuricae medicine are put into container, stir and grind to form fine powder;
2, Mel is refined into the tender honey of 110-115 DEG C;
3, stick together grinding for the spice of fine powder adds mixing system in Mel, then rubbing pill, every ball is containing pure medicine 1 gram.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510322662.5A CN104873700A (en) | 2015-06-14 | 2015-06-14 | Medicament for treating vascular headache and limb numbness and preparation method thereof |
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| CN201510322662.5A CN104873700A (en) | 2015-06-14 | 2015-06-14 | Medicament for treating vascular headache and limb numbness and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032604A (en) * | 2007-04-16 | 2007-09-12 | 北京艺信堂医药研究所 | Chinese medicine preparation for curing vascular type headache |
| CN103316067A (en) * | 2013-07-16 | 2013-09-25 | 冯宇伟 | Medicine for treating headache and preparation method thereof |
-
2015
- 2015-06-14 CN CN201510322662.5A patent/CN104873700A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032604A (en) * | 2007-04-16 | 2007-09-12 | 北京艺信堂医药研究所 | Chinese medicine preparation for curing vascular type headache |
| CN103316067A (en) * | 2013-07-16 | 2013-09-25 | 冯宇伟 | Medicine for treating headache and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 陈平安: "自拟丹钩汤治疗偏头痛 52例临床观察", 《中医药导报》 * |
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Application publication date: 20150902 |
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