CN104855850A - Nitraria tangutorum skin residue extract with anti-fatigue effect and preparation method thereof - Google Patents
Nitraria tangutorum skin residue extract with anti-fatigue effect and preparation method thereof Download PDFInfo
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- CN104855850A CN104855850A CN201510205039.1A CN201510205039A CN104855850A CN 104855850 A CN104855850 A CN 104855850A CN 201510205039 A CN201510205039 A CN 201510205039A CN 104855850 A CN104855850 A CN 104855850A
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- 239000000284 extract Substances 0.000 title claims abstract description 41
- 230000000694 effects Effects 0.000 title claims abstract description 25
- 230000002929 anti-fatigue Effects 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 241001104824 Nitraria tangutorum Species 0.000 title abstract description 12
- 238000005238 degreasing Methods 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000001914 filtration Methods 0.000 claims abstract description 6
- 238000004108 freeze drying Methods 0.000 claims abstract description 5
- 238000000605 extraction Methods 0.000 claims abstract description 4
- 239000002893 slag Substances 0.000 claims description 42
- 239000012535 impurity Substances 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 11
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 8
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- 239000000047 product Substances 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 4
- 238000007710 freezing Methods 0.000 claims description 4
- 230000008014 freezing Effects 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 4
- 238000010992 reflux Methods 0.000 claims description 4
- 239000013049 sediment Substances 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 3
- 235000021028 berry Nutrition 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
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- 239000003826 tablet Substances 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 abstract description 7
- 238000012545 processing Methods 0.000 abstract description 5
- 239000000843 powder Substances 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
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- 238000005119 centrifugation Methods 0.000 abstract 1
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- 210000005036 nerve Anatomy 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 235000013175 Crataegus laevigata Nutrition 0.000 description 16
- 244000265913 Crataegus laevigata Species 0.000 description 15
- 238000002137 ultrasound extraction Methods 0.000 description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 6
- 238000001035 drying Methods 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 241001165494 Rhodiola Species 0.000 description 4
- 229920002527 Glycogen Polymers 0.000 description 3
- 241000159206 Nitraria Species 0.000 description 3
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 229940096919 glycogen Drugs 0.000 description 3
- 230000002440 hepatic effect Effects 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000004064 recycling Methods 0.000 description 3
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 230000009182 swimming Effects 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- -1 (18 kinds more than Chemical class 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 240000000171 Crataegus monogyna Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241001104795 Nitraria sibirica Species 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical group 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 150000007946 flavonol Chemical class 0.000 description 1
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 description 1
- 235000011957 flavonols Nutrition 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 235000019990 fruit wine Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000001261 hydroxy acids Chemical class 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention belongs to the deep processing field of wild nitraria tangutorum fruits, and particularly relates to a nitraria tangutorum skin residue extract with an anti-fatigue effect and a preparation method thereof. The preparation method includes the following steps: selecting nitraria tangutorum skin residues, carrying out deslagging, degreasing, extraction, filtration, concentration, purification, centrifugation and freeze-drying, and the like. According to the present invention, the skin residues obtained by juicing the wild nitraria tangutorum fruits from the Qaidam Basin in the Qinghai Province are used as a raw material to be processed into the extract, and the final extract is dark brown powder. Active ingredients of the wild nitraria tangutorum fruits can be retained; the extract has effects of tonifying spleen and stomach, helping digestion, calming the nerves and the like; and the nitraria tangutorum extract has a significant anti-fatigue effect. Besides, the present invention provides a perfect technical solution for comprehensive utilization of the wild nitraria tangutorum fruit byproducts, i.e., the skin residues, and greatly improves the resource utilization of the wild nitraria tangutorum fruits from the Qaidam Basin.
Description
Technical field
The invention belongs to wild Nitraria tangutorum intensive processing field, be specifically related to a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof.
Background technology
Nitraria zygophyllaceae Nitraria wild bush plant, primary growth, in Gobi desert and Arid Desert Region, has the title of " desert cherry ", and its fruit is called as " the 3rd class fruit ", has huge economic utilization potential value.White thorn resource is at China's abundance, widely distributed, and area, the Qaidam Relatively centralized distribution in Qinghai, condition of utilization is superior.The white thorn in area, Qaidam is distributed in height above sea level more than 3000 meters free of contamination areas, resource is 150 ~ 2,000,000 mu, Relatively centralized distributes and has the Bai Cilinyue 500,000 mu of Development volue, often produce berry of nitraria tangutorum bobr amount 6 ~ 100,000 tons per year, produce white burbark slag about more than 20,000 ton per year, stock number is very abundant, urgently develops.According to the study, white thorn (comprising fruit juice, pericarp and Bai Ci seed) is containing abundant carrotene, carotenoid, vitamin, binary and ternary hydroxy acid, (18 kinds more than, amino acid, wherein 8 kinds of essential amino acids content are enriched), pectin, protopectin, flavonol, anthocyanin, polysaccharide, terpene, peptide, steroid, alkaloid and abundant tartaric acid, protein, arnotto element, various trace elements etc.The method be with wild white bur after squeezing, making beating the skin slag that obtains for raw material, the extract (main component is flavones and polysaccharose substance) that process selects removal of impurities, ultrasonic extraction obtains, remain the nutritional labelings such as the amino acid in skin slag, vitamin and mineral matter to greatest extent, make the accessory substance skin slag of white thorn processing obtain comprehensive utilization simultaneously.At present, about the patent of white thorn has 61, wherein patent of invention accounts for 90.2%(55 item), appearance patent accounts for 8.2%(5 item), utility model patent is less than 1.6%(1 item).Most of patent of announcing mainly concentrates on the aspects such as white thorn converted products, extracting method and Bai Ci artificial culture, comprises the processing method of nitraria sibirica pall juice, the processing method such as extraction process, nitraria fruit wine manufacture method, white thorn allantoin of white thorn haematochrome and the method such as abductive approach, nitraria seed quick germination of series of products and Bai Ci invisible cultural method, in vain thorn bruise tissue.About utilizing the exploitation of white thorn accessory substance skin slag to have the report of anti-fatigue effect little, this is the condition for the invention just.
Summary of the invention
The present invention have studied a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof, comprise select removal of impurities, ultrasonic extraction, concentrated, removal of impurities, centrifugal, drying and other steps make.This invention is that the comprehensive utilization of white thorn accessory substance pericarp provides a set of perfect technical scheme, breaches the present situation that wild white bur processes merely low value-added product.Accessory substance after this method makes white thorn processing is fully utilized, and has simple to operate, added value of product high.Raw material used in the present invention stings in vain and picks up from Qinghai-Tibet Platean, there is the feature of wild, pollution-free, pure natural etc., prepared white peronium slag extract can solve white burbark added value low, store the problems such as difficulty and contaminated environment, greatly improve the comprehensive utilization ratio of wild white thorn, therefore in the intensive processing of wild white thorn, there is certain novelty and practicality.
The present invention compared with prior art has the following advantages:
1, the present invention extracts for raw material with the skin slag of the Nitraria tangutorum in the Caidamu Basin after squeezing the juice, and more completely remains the nutritional labeling of wild white thorn.
2, the present invention has obvious anti-fatigue effect
With 6-8 week age, 20 ± 2 g cleaning grade Kunming mouses for experimental subjects, male and female half and half, are provided by Qinghai Province's Experimental Animal Center totally by 32.It is 4 groups by body weight random packet, often organize 8, after skin slag extract of the present invention is closed blank group (dosage is respectively 3g/Kg, 1.5 g/Kg, 1.5ml/Kg distilled waters, 3g/Kg rhodiola root) continuous gastric infusion 28d by high dose group, low dose group, positive drug group (rhodiola root), result is:
The white peronium slag extract of table 1 is on the impact of mouse lactic acid, urea nitrogen and hepatic glycogen
| Group | Lactic acid concn (mmol/L) | Urea nitrogen concentration (mmol/L) | Hepatic glycogen mg/g |
| Control group | 12.75±1.27 | 10.51±0.50 | 12.96±0.88 |
| High dose group | 22.39±1.43** | 11.67±1.28** | 18.43±1.37** |
| Low dose group | 18.68±1.62** | 10.05±0.36** | 14.61±0.81** |
| Rhodiola root group | 21.10±1.71 | 10.78±2.27 | 17.91±0.72 |
Note: * is P < 0.05, * * P < 0.01 compared with Normal group compared with Normal group
The white peronium slag extract of table 2 is on the impact of mice burden swimming time
| Sequence number | Group | Number of mice (only) | Walking weight load (min) |
| 1 | Control group | 8 | 5.16±1.01 |
| 2 | High dose group | 8 | 10.25±1.78** |
| 3 | Low dose group | 8 | 7.11±1.36* |
| 4 | Rhodiola root group | 8 | 9.01±2.06** |
Note: * is P < 0.05, * * P < 0.01 compared with Normal group compared with Normal group
In sum, the present invention stings accessory substance skin slag extract in vain and stings outside original health-care efficacy possessing wild white, the mice burden swimming time can also be significantly improved, increase hepatic glycogen content, reduce the lactic acid in mice serum and urea nitrogen content, show thus, in the present invention, in white thorn accessory substance skin slag, extract has obvious antifatigue effect.
Accompanying drawing explanation
Fig. 1 is a kind of white peronium slag extract with anti-fatigue effect of the present invention and preparation method thereof process chart.
Detailed description of the invention
Below in conjunction with drawings and Examples, a kind of white peronium slag extract with anti-fatigue effect of the present invention and preparation method thereof, technical scheme are further described.As shown in Figure 1, a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof, described raw material sting the high altitude localities (height above sea level more than 3600 meters) of pollution-free from Qinghai-Tibet Platean, pure green in vain, comprise the steps: that white thorn obtains white peronium slag after squeezing the juice, the selected removal of impurities of skin slag, degreasing, ultrasonic extraction, filtration, concentrated, removal of impurities, centrifugal, drying and other steps, use advanced person and the ultrasound assisted extraction technique of maturation, remain the nutriment in white burbark to greatest extent.
Embodiment 1: a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof, the selected removal of impurities of white peronium slag, degreasing, ultrasonic extraction, concentrated, removal of impurities, centrifugal, drying and other steps composition, white peronium slag crosses 30 mesh sieves and meal after selecting removal of impurities, removing sandstone; To reflux at 50 DEG C 3h by the benzinum of solid-liquid ratio 1:5 during degreasing, recycling design dry for standby; Control temperature 85 DEG C during ultrasonic extraction, solid-liquid ratio is the alcohol extract 1h with 40% under the condition of 1:10; 80 order silks are adopted to filter during filtration; Controlling negative pressure time concentrated is-0.06Mpa, and heating-up temperature 60 DEG C, being concentrated into solid content is 20
0bx; Chloroform and n-butanol are mixed in 5:1 ratio, the mixed liquor of its 0.2 times of volume is added in concentrate, vigorous stirring 30min in constant temperature blender with magnetic force, under the condition of rotating speed 3500rpm, refrigerated centrifuge 15min, discards lower sediment and organic solvent, collects supernatant, repeatedly, to without obvious deposited phenomenon; Supernatant dry 24h under the freezing conditions of vacuum-0.05Mpa, temperature-50 DEG C, both obtained extract powder.
Embodiment 2: a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof, the selected removal of impurities of white peronium slag, degreasing, ultrasonic extraction, concentrated, removal of impurities, centrifugal, drying and other steps composition, white peronium slag crosses 40 mesh sieves and meal after selecting removal of impurities, removing sandstone; To reflux at 70 DEG C 2h by the benzinum of solid-liquid ratio 1:10 during degreasing, recycling design dry for standby; Control temperature 90 DEG C during ultrasonic extraction, solid-liquid ratio is the alcohol extract 2h with 50% under the condition of 1:20; 100 order silks are adopted to filter during filtration; Controlling negative pressure time concentrated is-0.07Mpa, and heating-up temperature 70 DEG C, being concentrated into solid content is 30
0bx; Chloroform and n-butanol are mixed in 5:1 ratio, the mixed liquor of its 0.6 times of volume is added in concentrate, vigorous stirring 1h in constant temperature blender with magnetic force, under the condition of rotating speed 4200rpm, refrigerated centrifuge 10min, discards lower sediment and organic solvent, collects supernatant, repeatedly, to without obvious deposited phenomenon; Supernatant dry 18h under the freezing conditions of vacuum-0.06Mpa, temperature-57 DEG C, both obtained extract freeze-drying powder.
Embodiment 3: a kind of white peronium slag extract with anti-fatigue effect and preparation method thereof, the selected removal of impurities of white peronium slag, degreasing, ultrasonic extraction, concentrated, removal of impurities, centrifugal, drying and other steps composition, white peronium slag crosses 50 mesh sieves and meal after selecting removal of impurities, removing sandstone; To reflux at 90 DEG C 1h by the benzinum of solid-liquid ratio 1:15 during degreasing, recycling design dry for standby; Control temperature 95 DEG C during ultrasonic extraction, solid-liquid ratio is the alcohol extract 3h with 60% under the condition of 1:30; 120 order silks are adopted to filter during filtration; Controlling negative pressure time concentrated is-0.08Mpa, and heating-up temperature 80 DEG C, being concentrated into solid content is 40
0bx; Chloroform and n-butanol are mixed in 5:1 ratio, the mixed liquor of its 1 times of volume is added in concentrate, vigorous stirring 1.5h in constant temperature blender with magnetic force, under the condition of rotating speed 5000rpm, refrigerated centrifuge 5min, discards lower sediment and organic solvent, collects supernatant, repeatedly, to without obvious deposited phenomenon; Supernatant dry 12h under the freezing conditions of vacuum-0.07Mpa, temperature-64 DEG C, both obtained extract powder.
Claims (9)
1. white peronium slag extract with anti-fatigue effect and preparation method thereof, is characterized in that: preparation method comprises and selects removal of impurities, degreasing, extraction, filtration, concentrated, removal of impurities, centrifugal, freeze-drying eight steps.
2. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: white peronium slag coarse crushing when selecting removal of impurities also crosses 20-50 order sub-sieve.
3. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: raw material during degreasing: benzinum or ether=1:5-1:15, reflux 1-3h at 50-90 DEG C.
4. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: during extraction, the ethanol of 40%-60% extracts 1-3h by the amount of solid-liquid ratio 1:10-1:30 at 85-95 DEG C.
5. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: filter and refer to that white peronium slag extract 80-120 order silk filters.
6. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: controlling negative pressure of vacuum time concentrated is-0.06--0.08Mpa, and temperature is 60-80 DEG C, and being concentrated into solid content is 20-40
0bX.
7. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, it is characterized in that: chloroform and n-butanol are mixed in 5:1 ratio, the mixed liquor of its 0.2-1 times volume is added in concentrate, vigorous stirring 0.5-1.5h, under the condition of rotating speed 3500-5000rpm, refrigerated centrifuge 5-15min, discard lower sediment and organic solvent, collect supernatant, repeatedly, to existing without obvious precipitation.
8. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, is characterized in that: freeze-drying adopts freeze dryer to carry out freeze-drying, controls negative pressure-0.05 ~-0.07MPa, cryogenic temperature-50 ~-64 DEG C, freezing 12-24h.
9. a kind of white peronium slag extract with anti-fatigue effect according to claim 1 and preparation method thereof, it is characterized in that: raw material stings the accessory substance skin slag that obtains after squeezing the juice in vain for extracting raw material with the economic berry in the Caidamu Basin, the white peronium slag extract that the method obtains can be used as the additive of food, medicine, health products, can be developed into medicine or the health products of the forms such as tablet, capsule, particle.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105213442A (en) * | 2015-10-28 | 2016-01-06 | 青海尤尼克生物技术有限公司 | A kind of Fructus Nitraria schoberi extractive of general flavone and preparation method thereof |
| CN105232593A (en) * | 2015-10-28 | 2016-01-13 | 青海尤尼克生物技术有限公司 | Nitraria branch and leaf extract |
| CN105380968A (en) * | 2015-12-21 | 2016-03-09 | 中国人民解放军第二军医大学 | Nitraria-tangutorum-bobr total alkaloid extract, preparing method thereof and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213442A (en) * | 2015-10-28 | 2016-01-06 | 青海尤尼克生物技术有限公司 | A kind of Fructus Nitraria schoberi extractive of general flavone and preparation method thereof |
| CN105232593A (en) * | 2015-10-28 | 2016-01-13 | 青海尤尼克生物技术有限公司 | Nitraria branch and leaf extract |
| CN105380968A (en) * | 2015-12-21 | 2016-03-09 | 中国人民解放军第二军医大学 | Nitraria-tangutorum-bobr total alkaloid extract, preparing method thereof and application thereof |
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