CN104825910A - Traditional Chinese medicine preparation for secretory otitis media and its preparation method - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for secretory otitis media, made from ephedra, bitter apricot seed, chrysanthemum flower, cocklebur fruit, magnolia flower-bud, dahurian angelica root, peppermint, fineleaf schizonepeta herb, divaricate saposhnikovia root, honeysuckle bud and flower, weeping forsythia capsule, platycodon root, lophatherum herb, fermented soybean, great burdock achene, reed rhizome, Sichuan lovage rhizome, Chinese thorowax root, nutgrass galingale rhizome, cablin patchouli herb, sweet flag rhizome, peach seed, safflower, luffa vegetable sponge and beautiful sweetgum fruit, and belongs to the field of traditional Chinese medicine invention. According to the different characteristics, each of the traditional Chinese medicines is washed, cut and pretreated, and then prepared in proportion in a special preparation way. Thus the pharmacological actions of activating blood circulation to remove blood stasis, eliminating phlegm to be enlightened, dispelling wind and clearing heat, and removing toxicity to relieve swelling are achieved. The product mix and preparation method of the traditional Chinese medicine preparation are unique. Being proved by clinical trials, the traditional Chinese medicine preparation has the advantages that the treatment effect is significant, the treatment cycle is short, the cost is low, no adverse reactions and no toxic and side effects are generated, and broad market application prospect is achieved accordingly.

Description

A kind of for secretory otitis media Chinese medicine preparation and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of for secretory otitis media Chinese medicine preparation, the invention still further relates to the preparation method of this Chinese medicine preparation.

Background technology

The middle ear apyetous inflammatory diseases that secretory otitis media (secretory otitis media) is is principal character with hydrotympanum and auditory dysesthesia.Middle ear effusion can be serosity omission timber or transudate, also can be mucus.The cause of disease of current secretory otitis media is not yet completely clear and definite.Think main relevant with Eustachian tube disfunction, infection and immunity reaction etc.

Secretory otitis media belongs to the category of " bulge of the ear ", " deafness " in motherland's medical science, is the otopathy that is cardinal symptom with ear suffocation sense.Sick from the beginning of based on bulge of the ear, and see that ear is vexed, sick for a long time then in ear have thing resistance sense, auditory dysesthesia, be called deafness ".And study carefully its source, mostly be ailment said due to cold or exposure invasion and attack, dampness-heat in the liver and gallbladder, qi depression to blood stasis, heresy malicious stagnant internal organs deficient caused by.

The method of current doctor trained in Western medicine clinical treatment otitis media is still based on antibiotic, and due to the specific position of middle ear, make antibiotic therapeutic effect not good enough, patient creates Drug resistance to medicine after having taken a large amount of antibiotic often, and a large amount of antibiotic use simultaneously also creates serious toxic and side effects to the health of patient, and patient can be made to produce very large misery, therapeutic process again and again, DeGrain, expense is high, causes larger pressure at heart and ailing pressure to patient.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation for secretory otitis media, it is remarkable that this Chinese medicine preparation has therapeutic effect for treatment secretory otitis media, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.

Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of secretory otitis media repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.

The effect of Chinese medicine of the present invention:

Wherein:

Herba Ephedrae: be the dry herb stem of Ephedraceae plant plait Herba Ephedrae Ephedra sinica Stapf, epheday intermedia Ephedra intermedia Schrenk et C. A. Mey. or ephedra equisetina Ephedra equisetina Bge..Nature and flavor: pungent, micro-hardship, temperature.Gui Jing: return lung, urinary bladder channel.Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.Record in " Japan hanako materia medica ": logical nine orifices, blood circulation regulating, imperial epidemic pathogenic factors from mountains.

Semen Armeniacae Amarum: be the dry seed of the bitter in the mouth such as rosaceous plant Fructus Pruni or Prunus armeniaca L.var.ansu Maxim..Nature and flavor: bitter, temperature, poisonous.Return lung, large intestine channel.Effect: expelling phlegm for arresting cough, relievings asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Record in " herbal classic ": main cough with dyspnea is thundered, sore throat, the therapeutic method to keep the adverse QI flowing downwards, galactopoiesis incised wound, bitterly disappointed renal mass.

Flos Chrysanthemi: be the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.Record in " herbal classic ": main all dizziness due to wind, to swell and ache, order for de-, lacrimation, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, sharp vim and vigour.

Fructus Xanthii: be the fruit of the drying and ripening band involucre of feverfew Herba Xanthii Xanthium sibiricum Patr..Nature and flavor: pungent, bitter, temperature; Poisonous.Return lung meridian.Effect: Fructus Xanthii: loose wind dehumidifying, clearing the nasal passage.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.Record in " beautiful Chinese catalpa medicine solution ": numbness is opened in detumescence, and incessant sweating due to affection by pathogenic wind dries.Control scabies leprosy scabies urticaria.

Flos Magnoliae: be the dry flower of Magnoliacea plant Flos Magnoliae Magnolia biondii Pamp., Magnolia denudata Magnolia denudata Desv. or Flos Magnoliae Magnolia sprengeri Pamp..Nature and flavor: pungent, temperature.Attach to the lung and stomach meridians.Effect: dispersing wind and cold, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.Record in " Japan hanako materia medica ": clearance arteries and veins, improving eyesight.Control headache, the loathing of cold, body kept silent, pruritus.

The Radix Angelicae Dahuricae: be umbellate form section plant Radix Angelicae Dahuricae Angelica dahurica (Fisch.ex Hoffm.) Benth. et Hook.f. or Radix angelicae dahuricae Angelica dahurica(Fisch.ex Hoffm.) Benth.et Hook.f. var.formosana(Boiss.) dry root of Shan et Yuan.Nature and flavor: pungent, temperature.Return stomach, large intestine, lung meridian.Effect: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Record in " Japan hanako materia medica ": control conjunctival congestion bulbar conjunctiva polyp, and tire patching leaks landing, broken stagnated blood, mend fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, evacuation of pus, desolation, scabies, pain relieving granulation promoting, goes face Shao-defect scar.

Herba Menthae: be the dry aerial parts of Labiatae mint Herba Menthae Mentha haplocalyx Briq..Nature and flavor: pungent are cool.Return lung, Liver Channel.Effect: dispelling wind-heat.Refresh oneself, rash.For anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast the side of body feeling of distension and oppression.Record in " feeding habits book on Chinese herbal medicine ": all medicines can be drawn and join the army and defend.Treat YIN YANG toxin syndrome, cold headache.

Herba Schizonepetae: be the dry aerial parts of labiate Herba Schizonepetae Schizonepeta tenuifolia Briq..Nature and flavor: pungent, tepor.Return lung, Liver Channel.Effect: induce sweat loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.Record in " Japan hanako materia medica ": sharp the five internal organs, removing stagnancy of indigested food and making QI downward, relieving alcoholic intoxication.Heat-dissipating of cooking is eaten and is simmered tea, and controls wind syndrome of head and antiperspirant goes out; Semen Glycines preparatum decoct control violent trauma tremble with fear.

Radix Saposhnikoviae: be the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..Nature and flavor: acrid, sweet, warm.Return bladder, liver, spleen channel.Effect: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.Record in " not Lu ": hypochondriac pain, side of body public attention face is gone, and extremity contraction is anxious, convulsion in word milk gold skin ulcer.

Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.Record in " the SHENGCAO property of medicine is standby to be wanted ": energy eliminating carbuncle cellulitis furunculosis, dysentery relieving disease, washes chancre, peeling skin heat in blood.

Fructus Forsythiae: be the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Nature and flavor: bitter, are slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Record in " herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat.

Radix Platycodonis: be Campanulaceae Radix Platycodonis Platycodon grandiflorum(Jacq.) dry root of A.DC..Nature and flavor: bitter, pungent are flat.Return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.Record in " not Lu ": sharp the five internal organs the intestines and stomach, gas of enriching blood, except cold and heat, migratory arthralgia, warming middle-JIAO rapid digestion of food, treats laryngopharynx pain.

Herba Lophatheri: be the dry stem and leaf of grass Herba Lophatheri Lophatherum gracile Brongn..Nature and flavor: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Effect: clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.Record in " the SHENGCAO property of medicine is standby to be wanted ": expectorant is quenched the thirst, except part of the body cavity above the diaphragm housing the heart and lungs fire, bright eyes, diuresis, controls nebulousurine, brings down a fever, loose hemorrhoid poison.

Semen Sojae Preparatum: be legume soybean Glycine max(L.) the fermentation processing product of mature seed of Merr..Nature and flavor: bitter, pungent, cool.Attach to the lung and stomach meridians.Effect: induce sweat, relieving restlessness, a surname sends out hot and suffocating.For flu, cold and heat headache, fidgety uncomfortable in chest, restlessness of asrhenia type and insomnia.Record in " not Lu ": main cold headache cold and heat, miasma is vicious, and irritated full vexed, asthenia breathes heavily suction, and bipod pain is cold.

Fructus Arctii: be the dry mature fruit of feverfew Fructus Arctii Arctium lappa L..Nature and flavor: pungent, bitter, cold.Attach to the lung and stomach meridians.Effect: dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.Record in " property of medicine opinion ": except all wind, Li Yaojiao, again loose all tuberosity muscles and bones dysphoria with smothery sensation poison.

Rhizoma Phragmitis: be the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Nature and flavor: sweet, cold.Attach to the lung and stomach meridians.Effect: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Record in " not Lu ": main exopathogenic heat of quenching one's thirst, only normal urination.

Rhizoma Chuanxiong: be samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort.(or Ligusticum wallichii Franch.) dry rhizome.Nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Record in " Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken Disorder ties stagnated blood, supports fresh blood, puts on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood.

Radix Bupleuri (processed with vinegar): be the dry root vinegar goods of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..Nature and flavor: bitter, are slightly cold.Return liver, gallbladder meridian.Effect: reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.Record in " detailed outline ": control yang-energy and sink, suppressing the hyperactive liver, gallbladder, three burnt, envelope is mutually fiery.

Rhizoma Cyperi: be the dry rhizome of sedge dried tuber Cyperus rotundus L..Nature and flavor: pungent, micro-hardship, micro-sweet are flat.Return liver, spleen, tri-jiao channel.Effect: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Record in " detailed outline ": loose seasonal epidemic pathogens is trembled with fear epidemic disease, and profit three is burnt, and separate six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, hematochezia, hematuria, married woman's bleeding not during menses, the moon wait uncomfortable, before tire puerperal all kinds of diseases and ailments.

Herba Pogostemonis: be the herb of labiate Herba Pogostemonis or Herba Pogostemonis.Nature and flavor: pungent, tepor.Return lung, spleen, stomach warp.Effect: fast gas, and in, ward off dirty, damp eliminating.Cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Record in " pearl sac ": mend and defend gas, stomach reinforcing gas, enters diet, control again and tell inverse cholera.

Rhizoma Acori Graminei: be the rhizome of aroid Rhizoma Acori Graminei.Nature and flavor: acrid in the mouth, hardship, GUIXIN warm in nature, liver, stomach warp.Effect: waking up the patient from unconsciousness by dissipating phlegm; Dehumidifying stomach invigorating; Killing parasites for relieving itching.Main coma due to phlegm syncope; Apoplexy; Epilepsy; Palpitate with fear forgetful; Hiccough and deaf; Abdominal pain due to retention of food; Dysentery is had loose bowels; Rheumatalgia; Eczema; Scabies.

Semen Persicae: be the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Record in " herbal classic ": main blood stasis, blood closes lump in the abdomen, pathogen, kills small worm." not Lu ": only cough with dyspnea, disappear hardness in the epigastrium, and except soldier hits blood cruelly, broken lump in the abdomen, promotes blood circulation, pain relieving.

Flos Carthami: be the dried floral of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.

Retinervus Luffae Fructus: be the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae Luffa cylindrica (L.) Roem..Nature and flavor: sweet are flat.Return lung, stomach, Liver Channel.Effect: dredging collateral, invigorates blood circulation, and dispels the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis.Record in " book on Chinese herbal medicine is new again ": the meridian dredging, and blood vessels, reduce phlegm pleasant.

Fructus Liquidambaris: be the drying and ripening infructescence of Hamamelidaceae Plants Chinese sweet gum Liquidambar formosana Hance.Nature and flavor: bitter are flat.Return liver, kidney channel.Effect: dispelling, collateral-activating, diuretic stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.Record in " detailed outline is picked up any lost article from the road ": ward off miasma but pestilence, improving eyesight, dehumidifying, the contracture of relaxing muscles and tendons network, whole body arthralgia pain, trick and lumbago, its flue gas of smelling burnt all is healed.

Side's solution of the present invention is: Rhizoma Chuanxiong blood-activating and qi-promoting in side, Semen Persicae blood circulation promoting and blood stasis dispelling, Flos Carthami, Retinervus Luffae Fructus promoting blood circulation to restore menstrual flow, Rhizoma Acori Graminei waking up the patient from unconsciousness by dissipating phlegm, Herba Ephedrae is eliminated the phlegm and has one's ideas straightened out, Radix Platycodonis eliminates the phlegm evacuation of pus, Fructus Xanthii, the Radix Angelicae Dahuricae, Magnoliae Powder wind are sensible, and above nine taste medicines, as monarch drug in side, return liver, lung meridian, there is blood circulation promoting and blood stasis dispelling, the effect of having one's ideas straightened out of eliminating the phlegm.Ear is the institute of the clear positive intersection in the whole body, and logical kidney qi, connects liver, gallbladder two warp." dialectical record " is said: " few positive courage is not relaxed, and ailment said due to cold or exposure takes advantage of it, and fire must not fall apart, thus sick this." i.e. otitis media one disease, cover because of the imbalance of patient's liver and gall, clearing heat in QI system does not relax, and pathogenic wind toxic pathogenic heat is taken advantage of a favourable situation in invasion body, follows on shaoyang channel network and steams, so that heat stagnation blood network, and ear invaded by evil poison, and the scorching tympanum that burns, to give birth to inflammation.So blood circulation promoting and blood stasis dispelling, eliminating the phlegm has one's ideas straightened out is the basis for the treatment of secretory otitis media, and above nine taste medicines are monarch drug, and first fundamentally blood circulation promoting and blood stasis dispelling, eliminates the phlegm and have one's ideas straightened out, and make disease obtain basic control.Flos Chrysanthemi, the heat clearing away of Floris Lonicerae Powder wind, Fructus Forsythiae, Fructus Arctii heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Herba Lophatheri, Rhizoma Phragmitis clearing heat and relieving fidgetness, Herba Menthae dispelling wind-heat, ministerial drug in the above seven flavor medicine side of being, auxiliary monarch drug blood circulation promoting and blood stasis dispelling, eliminates the phlegm and has one's ideas straightened out on the one hand; There is as ministerial drug effect of loose wind heat clearing away, removing toxic substances and promoting subsidence of swelling on the other hand.Semen Armeniacae Amarum eliminates the phlegm the therapeutic method to keep the adverse QI flowing downwards, and Herba Schizonepetae is induced sweat loose wind, Radix Saposhnikoviae inducing diaphoresis to dispel wind, Semen Sojae Preparatum induces sweat relieving restlessness, Radix Bupleuri solution the exterior and the interior is soothing the liver, Rhizoma Cyperi promoting QI circulation for relieving depression, menstruction regulating and pain relieving, Herba Pogostemonis and middle damp eliminating, Fructus Liquidambaris dispelling, collateral-activating, above eight taste medicines, as adjuvant drug, cause the inducement of secretory otitis media, can promote the blood circulation promoting and blood stasis dispelling of the monarch and his subjects two medicine as adjuvant drug from pathology treatment, to eliminate the phlegm effect of having one's ideas straightened out, can promote that body falls apart wind heat clearing away, removing toxic substances and promoting subsidence of swelling by using corrigent the monarch and his subjects two medicine again.The all medicines of this side share, and the monarch and his subjects pull together, and minister assistant is altogether auxiliary, has blood circulation promoting and blood stasis dispelling, eliminate the phlegm have one's ideas straightened out, loose wind heat clearing away, removing toxic substances and promoting subsidence of swelling effect of effect, effectively can treat secretory otitis media.

Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.

Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Herba Ephedrae 8-12g, Semen Armeniacae Amarum 8-12g, Flos Chrysanthemi 7-11g, Fructus Xanthii 8-12g, Flos Magnoliae 8-12g, Radix Angelicae Dahuricae 8-12g, Herba Menthae 8-12g, Herba Schizonepetae 8-12g, Radix Saposhnikoviae 8-12g, Flos Lonicerae 18-22g, Fructus Forsythiae 10-14g, Radix Platycodonis 8-12g, Herba Lophatheri 8-12g, Semen Sojae Preparatum 8-12g, Fructus Arctii 13-17g, Rhizoma Phragmitis 8-12g, Rhizoma Chuanxiong 13-17g, Radix Bupleuri 18-22g, Rhizoma Cyperi 8-12g, Herba Pogostemonis 10-14g, Rhizoma Acori Graminei 8-12g, Semen Persicae 8-12g, Flos Carthami 8-12g, Retinervus Luffae Fructus 13-17g, Fructus Liquidambaris 13-17g.

Wherein be preferably: Herba Ephedrae 10g, Semen Armeniacae Amarum 10g, Flos Chrysanthemi 9g, Fructus Xanthii 10g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Herba Menthae 10g, Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Flos Lonicerae 20g, Fructus Forsythiae 12g, Radix Platycodonis 10g, Herba Lophatheri 10g, Semen Sojae Preparatum 10g, Fructus Arctii 15g, Rhizoma Phragmitis 10g, Rhizoma Chuanxiong 15g, Radix Bupleuri 20g, Rhizoma Cyperi 10g, Herba Pogostemonis 12g, Rhizoma Acori Graminei 10g, Semen Persicae 10g, Flos Carthami 10g, Retinervus Luffae Fructus 15g, Fructus Liquidambaris 15g.

A kind of preparation method of the Chinese medicine preparation for secretory otitis media is as follows:

Step one: by weight of the present invention, gets Radix Bupleuri, Rhizoma Cyperi respectively, and add rice vinegar and mix thoroughly, moistening is sucked to vinegar, and slow fire heats, fried dry, pulverizes, and crosses 120 mesh sieves, for subsequent use;

Step 2: by weight of the present invention, get Fructus Xanthii, Semen Armeniacae Amarum puts into marmite, adds 3-4 times of volume water, intense fire infusion 40-50 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use;

Step 3: by weight proportion of the present invention, get the Radix Angelicae Dahuricae, Herba Schizonepetae, Radix Saposhnikoviae, Radix Platycodonis, Fructus Arctii, Rhizoma Phragmitis, Rhizoma Chuanxiong, Rhizoma Acori Graminei, Retinervus Luffae Fructus medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion 20-30 minute, again Herba Ephedrae, Flos Chrysanthemi, Flos Magnoliae, Herba Menthae, Flos Lonicerae, Fructus Forsythiae, Herba Lophatheri, Semen Sojae Preparatum, Herba Pogostemonis, Semen Persicae, Flos Carthami, Fructus Liquidambaris are dropped in marmite, add 3 times of volume water, intense fire infusion 20-30 minute, lard speech with literary allusions and obtain filtrate in fiery infusion 20-30 minute, infusion merges gained filtrate three times repeatedly, for subsequent use;

Step 4: by step 2, three gained filtrates and the mixing of step one gained powder, stir evenly, both the decoction for the treatment of secretory otitis media of the present invention.

Using method of the present invention: get a secondary decoction, every day is oral meal at twice 7 days is a course for the treatment of.

Medicine of the present invention has blood circulation promoting and blood stasis dispelling, eliminate the phlegm have one's ideas straightened out, loose wind heat clearing away, removing toxic substances and promoting subsidence of swelling effect, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviates the slight illness of patient, adds up according to clinical 124 routine patient view, use medicine of the present invention the total effective rate course for the treatment of 90.3%, two the total effective rate course for the treatment of 97.6%.

Detailed description of the invention

Embodiment one: Herba Ephedrae 10g, Semen Armeniacae Amarum 10g, Flos Chrysanthemi 9g, Fructus Xanthii 10g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Herba Menthae 10g, Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Flos Lonicerae 20g, Fructus Forsythiae 12g, Radix Platycodonis 10g, Herba Lophatheri 10g, Semen Sojae Preparatum 10g, Fructus Arctii 15g, Rhizoma Phragmitis 10g, Rhizoma Chuanxiong 15g, Radix Bupleuri 20g, Rhizoma Cyperi 10g, Herba Pogostemonis 12g, Rhizoma Acori Graminei 10g, Semen Persicae 10g, Flos Carthami 10g, Retinervus Luffae Fructus 15g, Fructus Liquidambaris 15g.

Embodiment two: Herba Ephedrae 11g, Semen Armeniacae Amarum 9g, Flos Chrysanthemi 10g, Fructus Xanthii 10g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Herba Menthae 11g, Herba Schizonepetae 11g, Radix Saposhnikoviae 11g, Flos Lonicerae 21g, Fructus Forsythiae 11g, Radix Platycodonis 9g, Herba Lophatheri 8g, Semen Sojae Preparatum 10g, Fructus Arctii 16g, Rhizoma Phragmitis 11g, Rhizoma Chuanxiong 15g, Radix Bupleuri 20g, Rhizoma Cyperi 9g, Herba Pogostemonis 12g, Rhizoma Acori Graminei 11g, Semen Persicae 10g, Flos Carthami 10g, Retinervus Luffae Fructus 15g, Fructus Liquidambaris 16g.

Embodiment three: Herba Ephedrae 9g, Semen Armeniacae Amarum 11g, Flos Chrysanthemi 9g, Fructus Xanthii 11g, Flos Magnoliae 11g, Radix Angelicae Dahuricae 11g, Herba Menthae 11g, Herba Schizonepetae 11g, Radix Saposhnikoviae 11g, Flos Lonicerae 20g, Fructus Forsythiae 12g, Radix Platycodonis 10g, Herba Lophatheri 8g, Semen Sojae Preparatum 12g, Fructus Arctii 15g, Rhizoma Phragmitis 8g, Rhizoma Chuanxiong 13g, Radix Bupleuri 21g, Rhizoma Cyperi 11g, Herba Pogostemonis 12g, Rhizoma Acori Graminei 10g, Semen Persicae 9g, Flos Carthami 9g, Retinervus Luffae Fructus 14g, Fructus Liquidambaris 14g.

Just the clinical statistics data that patient uses medicine of the present invention below:

One, physical data

Accept out-patient 248 example for medical treatment, patient is divided into observation group and matched group at random, wherein male 160 example, women 88 example, M-F 1.8:1, max age 45 years old, minimal ages 18 years old, the course of disease time, not etc. every basic documents such as two groups of patient ages, sex, courses of disease were substantially not identical, no significant difference (P > 0.05).

Two, diagnostic criteria

Patient has that ear is in various degree stifled, ear is vexed, auditory dysesthesia, intermittent tinnitus or slight otalgia.Otoscopy: tympanum is complete, muddy, light cone distortion or disappearance, manubrium of malleus backward, cave in, and mobility is poor by top displacement; Or acoustic impedance audiometry ear is B type or C type curve, sound reflecting disappears, and pure tone threshold testing is not conductive deafness (20-50dB) not etc., and hearing loss is many with bass.

Three, Therapeutic Method:

1, observation group is according to Medications Example one of the present invention, and weighting raw materials is by the treatment of invention implementation method, and treatment group takes medicine of the present invention, and every day is oral meal at twice, within 7 days, is a course for the treatment of.2, matched group adopts conventional western medicine antibiotic therapy method, and the Ureteral Calculus phase is 7 days.

Four, efficacy assessment standard:

1, cure: clinical symptom disappearance, tympanum recovers normal, and hearing test shows that audition is normal;

2, take a turn for the better: clinical symptoms obviously alleviates, and tympanum hyperemia alleviates, in tympanum, hydrops disappears;

3, invalid: clinical symptoms has no improvement, hearing test has no change.

Five, therapeutic outcome statistics:

Matched group result is added up

Wherein: total effective rate=cure rate+improvement rate

Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of

Wherein: total effective rate=cure rate+improvement rate

Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness in treatment secretory otitis media, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.

Model case and curative effect:

Case one, patient Wang, man, 31 years old, people from Qingdao City, came here and goes to a doctor on January 18th, 2010.Oral account symptom is as follows: vexed swollen in 7 months vestibules, has and blocks sense, tinnitus, auditory dysesthesia.Find on inspection, membrana tympana auris dextrae is muddy, movable bad, puncture mostly is viscous light yellow hydrops.Electric audiometry test result: left ear conductive deafness, is diagnosed as secretory otitis media.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after two courses for the treatment of of treatment, effect is very good, and after half a year, Effect of follow-up visit by telephone does not recur.

Case two, patient Lee, female, 35 years old, people from Linyi, Shandong.Come here on May 14th, 2010 to go to a doctor, symptom is as follows after diagnosing: auris dextra auditory dysesthesia companion tinnitus, and the vexed swollen obturation sense of ear more than 30 skies, check and find, membrana tympana auris sinistrae is faint yellow, and tympanum thickens evagination, limitation of activity.Be diagnosed as secretory otitis media.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after two courses for the treatment of of treatment, effect is very good, and after half a year, Effect of follow-up visit by telephone does not recur.

Claims (4)

1. one kind for secretory otitis media Chinese medicine preparation, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Herba Ephedrae 8-12g, Semen Armeniacae Amarum 8-12g, Flos Chrysanthemi 7-11g, Fructus Xanthii 8-12g, Flos Magnoliae 8-12g, Radix Angelicae Dahuricae 8-12g, Herba Menthae 8-12g, Herba Schizonepetae 8-12g, Radix Saposhnikoviae 8-12g, Flos Lonicerae 18-22g, Fructus Forsythiae 10-14g, Radix Platycodonis 8-12g, Herba Lophatheri 8-12g, Semen Sojae Preparatum 8-12g, Fructus Arctii 13-17g, Rhizoma Phragmitis 8-12g, Rhizoma Chuanxiong 13-17g, Radix Bupleuri 18-22g, Rhizoma Cyperi 8-12g, Herba Pogostemonis 10-14g, Rhizoma Acori Graminei 8-12g, Semen Persicae 8-12g, Flos Carthami 8-12g, Retinervus Luffae Fructus 13-17g, Fructus Liquidambaris 13-17g.

2. the Chinese medicine preparation for secretory otitis media according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Herba Ephedrae 10g, Semen Armeniacae Amarum 10g, Flos Chrysanthemi 9g, Fructus Xanthii 10g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Herba Menthae 10g, Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Flos Lonicerae 20g, Fructus Forsythiae 12g, Radix Platycodonis 10g, Herba Lophatheri 10g, Semen Sojae Preparatum 10g, Fructus Arctii 15g, Rhizoma Phragmitis 10g, Rhizoma Chuanxiong 15g, Radix Bupleuri 20g, Rhizoma Cyperi 10g, Herba Pogostemonis 12g, Rhizoma Acori Graminei 10g, Semen Persicae 10g, Flos Carthami 10g, Retinervus Luffae Fructus 15g, Fructus Liquidambaris 15g.

3. the Chinese medicine preparation for secretory otitis media according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.

4. for a preparation method for the Chinese medicine preparation of secretory otitis media, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, gets Radix Bupleuri, Rhizoma Cyperi respectively, add rice vinegar to mix thoroughly, moistening is sucked to vinegar, and slow fire heats, fried dry, pulverize, cross 120 mesh sieves, for subsequent use; Step 2: by weight of the present invention, get Fructus Xanthii, Semen Armeniacae Amarum puts into marmite, adds 3-4 times of volume water, intense fire infusion 40-50 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use; Step 3: by weight proportion of the present invention, get the Radix Angelicae Dahuricae, Herba Schizonepetae, Radix Saposhnikoviae, Radix Platycodonis, Fructus Arctii, Rhizoma Phragmitis, Rhizoma Chuanxiong, Rhizoma Acori Graminei, Retinervus Luffae Fructus medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion 20-30 minute, again Herba Ephedrae, Flos Chrysanthemi, Flos Magnoliae, Herba Menthae, Flos Lonicerae, Fructus Forsythiae, Herba Lophatheri, Semen Sojae Preparatum, Herba Pogostemonis, Semen Persicae, Flos Carthami, Fructus Liquidambaris are dropped in marmite, add 3 times of volume water, intense fire infusion 20-30 minute, lard speech with literary allusions and obtain filtrate in fiery infusion 20-30 minute, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 4: by step 2, three gained filtrates and the mixing of step one gained powder, stir evenly, both the decoction for the treatment of secretory otitis media of the present invention.