CN105963647A - Medicine for treating chronic suppurative otitis media and preparation method thereof - Google Patents

Medicine for treating chronic suppurative otitis media and preparation method thereof Download PDF

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CN105963647A
CN105963647A CN201610564148.7A CN201610564148A CN105963647A CN 105963647 A CN105963647 A CN 105963647A CN 201610564148 A CN201610564148 A CN 201610564148A CN 105963647 A CN105963647 A CN 105963647A
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radix
rhizoma
herba
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甄建民
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract

The invention discloses a medicine for treating chronic suppurative otitis media and a preparation method thereof. The medicine is mainly prepared from the following ingredients in certain parts by weight: rhizoma anemarrhenae, common yam rhizome, red peony roots, rhizoma alismatis, lophatherum, honeysuckle flowers, forsythia, dandelions, corydalis bungeana turcz., baikal skullcap roots, phellodendron bark, houttuynia, licorice roots, bupleurum, dogwood, radix angelicae, broom cypress fruits, mulberry leaves, oldenlandia diffusa, curcuma roots and moutan bark. The medicine disclosed by the invention has the functions of clearing away heat and toxic materials, eliminating dampness and purging the pathogenic fire, strengthening the spleen and tonifying the lung as well as tonifying the liver and kidneys, has a high effect taking speed and a good curative effect when used for treating chronic suppurative otitis media, and can ensure that the chronic suppurative otitis media does not relapse.

Description

A kind of medicine treating chronic suppurative otitis media and preparation method thereof
Technical field
The present invention relates to a kind of medicine treating chronic suppurative otitis media and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Chronic suppurative otitis media refers to middle-ear mucosa, periosteum or the chronic suppurative inflammation as deep as sclerotin.Primary disease is facing On bed relatively conventional, often suppurate based in ear intermittently or continually property, the perforation of ear drum, auditory dysesthesia, can cause time serious intracranial, Complication outside cranium.The traditional Chinese medical science then thinks that chronic suppurative otitis media is burning hot with liver and gall, and stagnation of dampness due to deficiency of the spleen, deficiency of kidney-YIN is relevant.Due to Western medicine side effect is big, and therefore people exist great demand to the Chinese medicine of effectively treatment chronic suppurative otitis media, Up to now, the relevant report about the present invention is not the most found.
Summary of the invention
The research of the present inventor's foundation theory of Chinese medical science and the checking repeatedly of clinical trial, have found effectively treatment chronic finally The medicine of suppurative otitis media, thus complete the present invention.
It is an object of the invention to provide the Chinese medicine composition of a kind of effective treatment chronic suppurative otitis media.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select the Rhizoma Anemarrhenae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Rhizoma Alismatis, Herba Lophatheri, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Herba Violae, Huang A kind of reed mentioned in ancient books, Cortex Phellodendri, Herba Houttuyniae, Radix Glycyrrhizae, Radix Bupleuri, Fructus Corni, the Radix Angelicae Dahuricae, the Fructus Kochiae, Folium Mori, Herba Hedyotidis Diffusae, Radix Curcumae, Cortex Moutan, Herba Plantaginis Son, Radix Peucedani, Radix Ophiopogonis, Caulis Lonicerae, Caulis Akebiae, Radix Angelicae Sinensis, Rhizoma Cimicifugae, Caulis Spatholobi, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Fructus Trichosanthis, Cortex Mori, Radix Semiaquilegiae medicine It is combined preparation, these drug regimens make each efficacy of drugs produce synergism such that it is able to effectively treatment is chronic Suppurative otitis media.Wherein, the Rhizoma Anemarrhenae is selected to be because its nature and flavor bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize laxation Function, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Rhizoma Dioscoreae is selected to be because its nature and flavor sweet, Flat, enter lung, spleen, kidney channel, have spleen invigorating, tonifying the lung, reinforce the kidney, the function of benefit essence, control diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quench one's thirst, lose Essence, leukorrhagia, frequent micturition.Select Radix Paeoniae Rubra to be because its nature and flavor bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the merit of eliminating stasis to stop pain Can, control temperature poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, abdominal mass stomachache, injury from falling down, carbuncle skin infection. Rhizoma Alismatis is selected to be because its nature and flavor sweet, cold, enter bladder warp, have diuretic, eliminating dampness by diuresis, the function expelled the heat-evil, control dysuria, edema anus Full, vomiting, dysentery, phlegm retention, tinea pedis, gonorrhea, hematuria.Herba Lophatheri is selected to be because its property slightly sweet flavor, cold, enter heart kidney two warp, have Clearing away heart-fire, heat clearing away and restlessness relieving, the function of diuresis, control calentura thirsty, vexed, hot urination, stranguria with turbid discharge, erosion of the oral mucosa tongue boil, gingival swelling and pain.Choosing It is because its nature and flavor sweet with Flos Lonicerae, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle Infections, toxic swelling, scrofula, anal fistula.Fructus Forsythiae is selected to be because its nature and flavor bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, disappear Swollen function, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Herba Taraxaci is selected to be because its property bitter but sweet flavor, Cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, urgency Membranous conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Optionally It is bitter that fourth is because its nature and flavor, cold, enters the heart, Liver Channel, has clearing away heat-damp and promoting diuresis, the function of removing toxic substances and promoting subsidence of swelling, controls furuncle, carbuncle, scrofula, Huang Subcutaneous ulcer, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Radix Scutellariae is selected to be because its nature and flavor bitter, cold, enter the heart, lung, gallbladder, large intestine channel, There are removing the relative excess fire, dehumidifying heat, hemostasis, antiabortive function, control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, Collapse, leak, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Cortex Phellodendri is selected to be because its nature and flavor bitter, cold, enter kidney, bladder warp, have clear Heat, dampness, pathogenic fire purging, the function of removing toxic substances, control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice, flaccidity, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, red and white leukorrhea Under, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.Herba Houttuyniae is selected to be because its nature and flavor pungent, cold, start with lunar Warp, has heat-clearing and toxic substances removing, and the function of inducing diuresis to remove edema controls pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid Skin ulcer, proctoptosis, eczema, tinea alba, scabies.Select Radix Glycyrrhizae to be because its nature and flavor sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, Removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, loose stool of suffering from abdominal pain, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, Raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solve poison of drug and alimentary toxicosis.Radix Bupleuri is selected to be because its nature and flavor bitter, Cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, mesh of having a headache Dizzy, malaria, lower profit proctoptosis, menoxenia, uterine prolapse.Select Fructus Corni to be because its nature and flavor acid, tepor, enter liver, kidney channel, have Invigorating the liver and kidney, arresting seminal emission gas, Gu the function of collapse, control soreness of waist and knee joint, dizziness, tinnitus, sexual impotence, pass out semen, frequent micturition, deficiency of the liver cold and heat, Incessant sweating due to debility, the heart shakes scattered pulse.The Radix Angelicae Dahuricae is selected to be because its nature and flavor pungent, temperature, enter lung, spleen, stomach warp, dispel the wind, dampness, detumescence, only The function of pain, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin is dry Itch, scabies.The Fructus Kochiae is selected to be because its nature and flavor sweetness and bitterness, cold, enter kidney, bladder warp, have diuresis, the function of clearing away damp-heat, control little The most unfavorable, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.Folium Mori are selected to be because its property bitter but sweet flavor, cold, enter Lung, Liver Channel, have expelling wind and clearing away heat, the function of cooling blood for improving eyesight, and dispelling the wind and dampness pathogens generates heat, headache, and conjunctival congestion is thirsty, cough due to lung-heat, migratory arthralgia, addiction Rash, lower limb elephatiasis.Herba Hedyotidis Diffusae is selected to be because its property bitter but sweet flavor, cold, enter the heart, liver, spleen three warp, have heat clearing away, dampness removing, solve The function of poison, controls dyspnea and cough due to lung-heat, tonsillitis, pharyngolaryngitis, appendicitis, dysentery, jaundice, pelvic inflammatory disease, adnexitis, carbuncle furuncle, Venom.Select Radix Curcumae to be because its nature and flavor to work hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, Control the chest and abdomen side of body all pains of rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Cortex Moutan It is because its nature and flavor to work hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, control the pathogenic heat attacking blood system in febrile diseases, send out speckle, Frightened, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea, abdominal mass, carbuncle and ulcer, flutter damage.Semen Plantaginis is selected to be because its nature and flavor sweet, cold, enter Kidney, bladder warp, have diuretic, heat clearing away, improving eyesight, the function eliminated the phlegm, and controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough Excessive phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Select Radix Peucedani to be because its nature and flavor pungent, bitter, be slightly cold, return lung meridian, have scattered wind heat clearing away, lowering the adverse-rising QI to resolve phlegm Function, control cough due to pathogenic wind-heat, abundant expectoration, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, Stomach, heart channel, have nourishing YIN and moistening the lung, and clear away heart-fire relieving restlessness, the function of reinforcing stomach reg fluid, controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, and lung abscess is empty Labor dysphoria with smothery sensation, the most yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Caulis Lonicerae is selected to be because its nature and flavor sweet, cold, enter the heart, lung meridian, have clear Heat, removing toxic substances, the function of dredging collateral, control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.Select Caulis Akebiae It is because its nature and flavor bitter, cool, enter the heart, small intestinal, bladder warp, have pathogenic fire purging row water, the function of promoting blood circulation, control hot urination, stranguria with turbid discharge, Edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.Radix Angelicae Sinensis is selected to be because its nature and flavor sweet pungent, Temperature, enters the heart, liver, spleen channel, has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes the function of laxation, controls menoxenia, and amenorrhea is suffered from abdominal pain, and abdominal mass is tied Poly-, metrorrhagia, headache due to deficiency of blood, dizziness, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Rhizoma Cimicifugae It is because the sweet pungent micro-hardship of its nature and flavor, cool, enter lung, spleen, stomach warp, have yang invigorating, deliver, rash, the function of removing toxic substances, control seasonal epidemic pathogens epidemic disease labor, Headache cold and heat, laryngalgia, aphtha scar, macule is impermeable, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, and uterus drops, carbuncle skin ulcer Poison.Select Caulis Spatholobi be because its property bitter but sweet flavor, temperature, enter the heart, spleen two warp, have invigorate blood circulation, the function of relaxing muscles and tendons, control soreness of waist and knee joint, fiber crops Wood paralysis, menoxenia.The Rhizoma Atractylodis Macrocephalae is selected to be because its property bitter but sweet flavor, temperature, enter spleen, stomach warp, have a spleen reinforcing, stomach reinforcing, dampness, and in Function, controls deficient QI of the spleen and stomach, anorexia, the few gas of asthenia, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, head Dizzy, spontaneous perspiration, nausea is uneasy.Semen Coicis is selected to be because its property slightly sweet flavor, cool, enter spleen, lung, kidney channel, have a spleen invigorating, tonifying the lung, heat clearing away, The function of dampness removing, controls and has loose bowels, arthralgia chiefly caused by damp pathogen, muscle arteries and veins contracture, joint stuffiness, edema, tinea pedis, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea. Pericarpium Trichosanthis is selected to be because its nature and flavor sweet, cold, attach to the lung and stomach meridians, have removing heat-phlegm, the function of promoting the circulation of QI the chest stuffiness relieving, control phlegm-heat cough, breast Vexed hypochondriac pain.Cortex Mori is selected to be because its nature and flavor sweet, cold, enter lung, spleen channel, have eliminating pathogen from the lung for relieving asthma, the function of line water detumescence, control lung-heat Breath with cough, spit blood, edema, tinea pedis, dysuria.Radix Semiaquilegiae is selected to be because its nature and flavor sweetness and bitterness, cold, enter spleen, small intestinal, bladder three Warp, has heat clearing away, removing toxic substances, detumescence, eliminating stagnation, and the function of diuresis controls carbuncle, scrofula, furuncle, stranguria with turbid discharge, leukorrhagia, cough due to deficiency of the lung, hernia, Insane, infantile convulsion, hemorrhoid, traumatic injury.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, the consumption of each component under All there is in stating weight range preferable curative effect:
Rhizoma Anemarrhenae 5-15 gram, Rhizoma Dioscoreae 5-15 gram, Radix Paeoniae Rubra 5-15 gram, Rhizoma Alismatis 10-15 gram, Herba Lophatheri 5-10 gram, Flos Lonicerae 10-20 gram, Fructus Forsythiae 10-20 gram, Herba Taraxaci 10-20 gram, Herba Violae 5-15 gram, Radix Scutellariae 5-15 gram, Cortex Phellodendri 5-15 gram, Herba Houttuyniae 10-15 gram, Radix Glycyrrhizae 5-15 gram, Radix Bupleuri 5-15 gram, Fructus Corni 5-10 gram, Radix Angelicae Dahuricae 5-15 gram, Fructus Kochiae 5-15 gram, 5-15 gram of Folium Mori, Herba Hedyotidis Diffusae 10-15 gram, Radix Curcumae 10-15 gram, Cortex Moutan 10-20 gram, Semen Plantaginis 10-15 gram, Radix Peucedani 5-10 gram, Radix Ophiopogonis 5-12 gram, Caulis Lonicerae 10-20 gram, Caulis Akebiae 5-15 gram, Radix Angelicae Sinensis 10-15 gram, Rhizoma Cimicifugae 5-15 gram, Caulis Spatholobi 10-20 gram, Rhizoma Atractylodis Macrocephalae 10-15 gram, Semen Coicis 10- 20 grams, Fructus Trichosanthis 10-15 gram, Cortex Mori 5-15 gram, Radix Semiaquilegiae 5-15 gram.
It is preferably:
The Rhizoma Anemarrhenae 10 grams, Rhizoma Dioscoreae 10 grams, Radix Paeoniae Rubra 10 grams, Rhizoma Alismatis 12 grams, Herba Lophatheri 8 grams, Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Herba Taraxaci 15 grams, Herba Violae 10 grams, Radix Scutellariae 10 grams, Cortex Phellodendri 10 grams, Herba Houttuyniae 12 grams, 10 grams of Radix Glycyrrhizae, Radix Bupleuri 10 grams, Fructus Corni 8 grams, the Radix Angelicae Dahuricae 10 Gram, the Fructus Kochiae 10 grams, 10 grams of Folium Mori, Herba Hedyotidis Diffusae 12 grams, Radix Curcumae 12 grams, Cortex Moutan 15 grams, Semen Plantaginis 12 grams, Radix Peucedani 10 Gram, Radix Ophiopogonis 10 grams, Caulis Lonicerae 15 grams, Caulis Akebiae 10 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Cimicifugae 10 grams, Caulis Spatholobi 15 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Semen Coicis 15 grams, Fructus Trichosanthis 12 grams, Cortex Mori 10 grams, Radix Semiaquilegiae 10 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Rhizoma Anemarrhenae: pick clean impurity, hits with water and washes, pull out, soften, and section is dried;
2, Rhizoma Dioscoreae: pick clean impurity, is soaked in water softening to Rhizoma Dioscoreae central part, pulls out and slightly dry in the air, and section is dried or dried;
3, Radix Paeoniae Rubra: take crude drug, removes impurity, size stepping, cleans, run through, shave, be dried, and sieve removes chip;
4, Rhizoma Alismatis: pick decontamination, size stepping, is soaked in water to eighty per cant thoroughly, pulls out, shine cool, and moistening to inside and outside humidity is uniform, cuts Sheet, dries;
5, Herba Lophatheri: pick decontamination and root, cutting, dry;
6, Flos Lonicerae: sieve removes silt, picks clean impurity;
7, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
8, Herba Taraxaci: pick decontamination, cleans earth, cutting, dries;
9, Herba Violae: pick clean impurity, washes earth, cutting with water, dries;
10, Radix Scutellariae: pick decontamination, removes residual stem, infiltrates with cold water or puts slightly leaching in boiled water and pulls out, and section is dried;
11, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, section or shredding, dries;
12, Herba Houttuyniae: remove impurity, removes undesirable root, cleans cutting, dries;
13, Radix Glycyrrhizae: pick decontamination, cleans, be soaked in water to eighty per cant thoroughly time, pull out, run through, section, airing;
14, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, and after running through, section in time, dries immediately;
15, Fructus Corni: clean, removes pit and impurity, dries;
16, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, cut Sheet is dried;
17, the Fructus Kochiae: take crude drug, removes impurity, and sieve removes chip;
18, Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
19, Herba Hedyotidis Diffusae: take crude drug, removes impurity, and wash quickly is clean, slightly dries in the air, cutting, is dried, sieve dedusting bits;
20, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section is dried;
21, Cortex Moutan: pick decontamination, removes core, cleans, runs through, and section is dried;
22, Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
23, Radix Peucedani: take crude drug, removes impurity, cleans, runs through, shave, is dried or cold drying, and sieve removes chip;
24, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, after running through, pump the heart, then clean and dry;
25, Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, section, dries;
26, Caulis Akebiae: slightly soak with water, moistening, to thoroughly, is cut into slices, is dried;
27, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, slightly dries in the air, and section is dried;
28, Rhizoma Cimicifugae: pick decontamination, slightly foam washing are clean, pull out, run through, and section is dried;
29, Caulis Spatholobi: run through with water, section, or steam soft after take advantage of fervent sheet, dry;
30, the Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dry;
31, Semen Coicis: take crude drug, removes residual cot, impurity;
32, Fructus Trichosanthis: take crude drug, removes impurity and fruit stem, cleans, and flattens, shredding or fritter, is dried;
33, Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
34, Radix Semiaquilegiae: clear water is cleaned, section, dry.
Two, preparation
1, will concoct after the Rhizoma Anemarrhenae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Rhizoma Alismatis, Herba Lophatheri, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Herba Violae, Radix Scutellariae, Cortex Phellodendri, Herba Houttuyniae, Radix Glycyrrhizae, Radix Bupleuri, Fructus Corni, the Radix Angelicae Dahuricae, the Fructus Kochiae, Folium Mori, Herba Hedyotidis Diffusae, Radix Curcumae, Cortex Moutan, Semen Plantaginis, Radix Peucedani, Radix Ophiopogonis, Caulis Lonicerae, Caulis Akebiae, Radix Angelicae Sinensis, Rhizoma Cimicifugae, Caulis Spatholobi, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Fructus Trichosanthis, Cortex Mori, Radix Semiaquilegiae put into decocting container In, add water 8 times amount for the first time, and after soaking 100 minutes, intense fire decocts boiling, then with slow fire boiling 20 minutes, filters for the first time Decoction liquor, pours into first time decoction liquor in container;
2, the medicinal residues of filtration being added 6 times amount, intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
3, by twice decoction liquor mixing and stirring, it is divided into 4 doses to take.
In prescription, Cortex Phellodendri has heat clearing away, dampness, pathogenic fire purging, and the function of removing toxic substances is monarch drug;Semen Coicis spleen invigorating, tonifying the lung, heat clearing away, profit Wet;Fructus Forsythiae has heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, and the two is ministerial drug, and three taste medicines play heat clearing away, dampness, pathogenic fire purging jointly, solve Poison, eliminating stagnation, detumescence, spleen invigorating, the effect of tonifying the lung, treatment chronic suppurative otitis media effect is comprehensive, and with heat-clearing and toxic substances removing, dampness is rushed down Fire, strengthening the spleen and tonifying the lung, is that master can be effected a permanent cure, and Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, and coordinating the actions of various ingredients in a prescription controls weakness of the spleen and stomach, solve poison of drug and The function of alimentary toxicosis is adjuvant drug, and Fructus Corni has invigorating the liver and kidney, arresting seminal emission gas, Gu the function of collapse is for making medicine, medicine all with remainder is to control Mark.
Medicine of the present invention has heat-clearing and toxic substances removing, dampness pathogenic fire purging, strengthening the spleen and tonifying the lung, the function of invigorating the liver and kidney, is used for treating chronicity Purulent otitis media, short treating period, instant effect, non-relapse after healing.
Detailed description of the invention:
The beneficial effect of of the present invention medicine is expanded on further below by way of test example, these test examples include medicine of the present invention The animal toxicity test report of thing and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Taking rabbit 30, male and female dual-purpose, body weight 2.0 2.5kg, divide two groups, often group 15, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is that administration by gavage is given Medicine, twice daily, serve on 7 days, observes every day and is administered reaction, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad Toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept chronic suppurative otitis media out-patient totally 36 example for medical treatment.
2, diagnostic criteria
Classical symptom is that ear suppurates, and can have conductivity in various degree or Combination hearing loss, and some patients has tinnitus, many Impaired with internal ear relevant;Less patient is had to there will be the symptoms such as dizziness.
3, Therapeutic Method
Selecting above-mentioned medicament, take to patient, each take 1 dose, morning every day, evening respectively take 1 time, within 7 days, are a course for the treatment of, take continuously With 3 courses for the treatment of.
4, efficacy assessment standard
Effective: chronic suppurative otitis media transference cure, body constitution recovers normal, recovery from illness;
Taking a turn for the better: patient's ear inflammation, suppurate, the phenomenon of auditory dysesthesia and tinnitus alleviates, and chronic suppurative otitis media symptom is obvious Taking a turn for the better, body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (see table)
In above-mentioned treatment, with Drug therapy chronic suppurative otitis media patient 36 example of the present invention, effective 29 examples of result, obvious effective rate Being 80.55%, take a turn for the better 5 examples, and improvement rate is 13.88%, invalid 2 examples, and total effective rate is 94.43%.

Claims (3)

1. the medicine treating chronic suppurative otitis media, it is characterised in that: it is by the crude drug in following weight range Make:
Rhizoma Anemarrhenae 5-15 gram, Rhizoma Dioscoreae 5-15 gram, Radix Paeoniae Rubra 5-15 gram, Rhizoma Alismatis 10-15 gram, Herba Lophatheri 5-10 gram, Flos Lonicerae 10-20 gram, Fructus Forsythiae 10-20 gram, Herba Taraxaci 10-20 gram, Herba Violae 5-15 gram, Radix Scutellariae 5-15 gram, Cortex Phellodendri 5-15 gram, Herba Houttuyniae 10-15 gram, Radix Glycyrrhizae 5-15 gram, Radix Bupleuri 5-15 gram, Fructus Corni 5-10 gram, Radix Angelicae Dahuricae 5-15 gram, Fructus Kochiae 5-15 gram, 5-15 gram of Folium Mori, Herba Hedyotidis Diffusae 10-15 gram, Radix Curcumae 10-15 gram, Cortex Moutan 10-20 gram, Semen Plantaginis 10-15 gram, Radix Peucedani 5-10 gram, Radix Ophiopogonis 5-12 gram, Caulis Lonicerae 10-20 gram, Caulis Akebiae 5-15 gram, Radix Angelicae Sinensis 10-15 gram, Rhizoma Cimicifugae 5-15 gram, Caulis Spatholobi 10-20 gram, Rhizoma Atractylodis Macrocephalae 10-15 gram, Semen Coicis 10- 20 grams, Fructus Trichosanthis 10-15 gram, Cortex Mori 5-15 gram, Radix Semiaquilegiae 5-15 gram.
Medicine the most according to claim 1, the consumption of the most each crude drug is:
The Rhizoma Anemarrhenae 10 grams, Rhizoma Dioscoreae 10 grams, Radix Paeoniae Rubra 10 grams, Rhizoma Alismatis 12 grams, Herba Lophatheri 8 grams, Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Herba Taraxaci 15 grams, Herba Violae 10 grams, Radix Scutellariae 10 grams, Cortex Phellodendri 10 grams, Herba Houttuyniae 12 grams, 10 grams of Radix Glycyrrhizae, Radix Bupleuri 10 grams, Fructus Corni 8 grams, the Radix Angelicae Dahuricae 10 Gram, the Fructus Kochiae 10 grams, 10 grams of Folium Mori, Herba Hedyotidis Diffusae 12 grams, Radix Curcumae 12 grams, Cortex Moutan 15 grams, Semen Plantaginis 12 grams, Radix Peucedani 10 Gram, Radix Ophiopogonis 10 grams, Caulis Lonicerae 15 grams, Caulis Akebiae 10 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Cimicifugae 10 grams, Caulis Spatholobi 15 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Semen Coicis 15 grams, Fructus Trichosanthis 12 grams, Cortex Mori 10 grams, Radix Semiaquilegiae 10 grams.
The preparation method of medicine the most according to claim 1 or claim 2, it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Anemarrhenae: pick clean impurity, hits with water and washes, pull out, soften, and section is dried;
(2) Rhizoma Dioscoreae: pick clean impurity, is soaked in water softening to Rhizoma Dioscoreae central part, pulls out and slightly dry in the air, and section is dried or dried;
(3) Radix Paeoniae Rubra: take crude drug, removes impurity, size stepping, cleans, run through, shave, be dried, and sieve removes chip;
(4) Rhizoma Alismatis: pick decontamination, size stepping, is soaked in water to eighty per cant thoroughly, pulls out, shine cool, and moistening to inside and outside humidity is uniform, Section, dries;
(5) Herba Lophatheri: pick decontamination and root, cutting, dry;
(6) Flos Lonicerae: sieve removes silt, picks clean impurity;
(7) Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
(8) Herba Taraxaci: pick decontamination, cleans earth, cutting, dries;
(9) Herba Violae: pick clean impurity, washes earth, cutting with water, dries;
(10) Radix Scutellariae: pick decontamination, removes residual stem, infiltrates with cold water or puts slightly leaching in boiled water and pulls out, and section is dried;
(11) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, section or shredding, dries;
(12) Herba Houttuyniae: remove impurity, removes undesirable root, cleans cutting, dries;
(13) Radix Glycyrrhizae: pick decontamination, cleans, be soaked in water to eighty per cant thoroughly time, pull out, run through, section, airing;
(14) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, and after running through, section in time, dries immediately;
(15) Fructus Corni: clean, removes pit and impurity, dries;
(16) Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, cut Sheet is dried;
(17) Fructus Kochiae: take crude drug, removes impurity, and sieve removes chip;
(18) Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
(19) Herba Hedyotidis Diffusae: take crude drug, removes impurity, and wash quickly is clean, slightly dries in the air, cutting, is dried, sieve dedusting bits;
(20) Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section is dried;
(21) Cortex Moutan: pick decontamination, removes core, cleans, runs through, and section is dried;
(22) Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
(23) Radix Peucedani: take crude drug, removes impurity, cleans, runs through, shave, is dried or cold drying, and sieve removes chip;
(24) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, after running through, pump the heart, then clean and dry;
(25) Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, section, dries;
(26) Caulis Akebiae: slightly soak with water, moistening, to thoroughly, is cut into slices, is dried;
(27) Radix Angelicae Sinensis: pick decontamination, cleans, moistening, slightly dries in the air, and section is dried;
(28) Rhizoma Cimicifugae: pick decontamination, slightly foam washing are clean, pull out, run through, and section is dried;
(29) Caulis Spatholobi: run through with water, section, or steam soft after take advantage of fervent sheet, dry;
(30) Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dry;
(31) Semen Coicis: take crude drug, removes residual cot, impurity;
(32) Fructus Trichosanthis: take crude drug, removes impurity and fruit stem, cleans, and flattens, shredding or fritter, is dried;
(33) Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
(34) Radix Semiaquilegiae: clear water is cleaned, section, dry;
(2) prepare
(1) Rhizoma Anemarrhenae after concocting, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Rhizoma Alismatis, Herba Lophatheri, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Herba Violae, Radix Scutellariae, Huang Cypress, Herba Houttuyniae, Radix Glycyrrhizae, Radix Bupleuri, Fructus Corni, the Radix Angelicae Dahuricae, the Fructus Kochiae, Folium Mori, Herba Hedyotidis Diffusae, Radix Curcumae, Cortex Moutan, Semen Plantaginis, front Recklessly, Radix Ophiopogonis, Caulis Lonicerae, Caulis Akebiae, Radix Angelicae Sinensis, Rhizoma Cimicifugae, Caulis Spatholobi, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Fructus Trichosanthis, Cortex Mori, Radix Semiaquilegiae put into appearance of boiling medicine In device, add water 8 times amount, and after soaking 100 minutes, intense fire decocts boiling, then with slow fire boiling 20 minutes, filters to decoct for the first time Liquid, pours into first time decoction liquor in container;
(2) add water 6 times amount by the medicinal residues of filtration, and intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, it is divided into 4 doses to take.
CN201610564148.7A 2016-07-18 2016-07-18 Medicine for treating chronic suppurative otitis media and preparation method thereof Withdrawn CN105963647A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825910A (en) * 2015-06-04 2015-08-12 李元庆 Traditional Chinese medicine preparation for secretory otitis media and its preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825910A (en) * 2015-06-04 2015-08-12 李元庆 Traditional Chinese medicine preparation for secretory otitis media and its preparation method

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