CN104800495A

CN104800495A - Medicine for treating pneumothorax and preparation method thereof

Info

Publication number: CN104800495A
Application number: CN201510235397.7A
Authority: CN
Inventors: 徐东
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-11
Filing date: 2015-05-11
Publication date: 2015-07-29

Abstract

The invention discloses a medicine for treating pneumothorax and a preparation method thereof. The medicine is prepared by taking prepared rehmannia root, dogwood, codonopsis pilosula, Chinese yam, fructus perillae, poria cocos, schisandra chinensis and magnet at certain weight ratio. The medicine provided by the invention has the functions of eliminating dampness and diuresis, depressing qi and widening intestines, removing internal cold, warming spleen and stomach, promoting blood circulation and moistening lung. The medicine used for treating the pneumothorax can quickly become effective, has an excellent curative effect and can ensure that pneumothorax no longer relapses.

Description

A kind of medicine for the treatment of pneumothorax and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of pneumothorax and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Pneumothorax refers to that gas enters pleural space, causes pneumatosis state, is called pneumothorax.How because pulmonary disease or external force impact make lung tissue and visceral pleura break, or the trickle edema due to disorder of QI follicular rupture near lung surface, in lung and bronchus, air escapes into pleural space.Be more common in male person between twenty and fifty or suffer from chronic bronchitis, emphysema, pulmonary tuberculosis person.One of primary disease Shu Fei section emergency case, severe patient can threat to life, and process in time can be cured. because Western medicine cannot effective fast treating pneumothorax, therefore there is great demand in the Chinese medicine of people to effective treatment pneumothorax, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment pneumothorax, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment pneumothorax.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Radix Rehmanniae Preparata, Fructus Corni, Radix Codonopsis, Rhizoma Dioscoreae, Fructus Perillae, Poria, Fructus Schisandrae Chinensis, Magnetitum, Cortex Cinnamomi, Lignum Aquilariae Resinatum, Gecko, Radix Glycyrrhizae medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat pneumothorax.Wherein, select Radix Rehmanniae Preparata to be that tepor, enters liver, kidney channel, have YIN nourishing, and the function of enriching blood controls deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency because its nature and flavor are sweet, seminal emission, metrorrhagia, menoxenia, quenches one's thirst, frequency of micturition, deaf, blurred vision.Fructus Corni is selected to be that tepor, has invigorating the liver and kidney, arresting seminal emission gas, Gu the function of collapse, controls sexual impotence, and seminal emission, deficiency of the liver cold and heat, the heart shakes scattered pulse because its nature and flavor acid.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, have spleen invigorating, tonifying the lung, reinforce the kidney, the function of benefit essence, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.Fructus Perillae is selected to be that temperature, enter lung, large intestine channel, have the therapeutic method to keep the adverse QI flowing downwards, expectorant, lung moistening, the function of wide intestinal, controls cough with dyspnea, phlegm dyspnea, the stagnation of QI, constipation because its nature and flavor are pungent.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Fructus Schisandrae Chinensis is selected to be that temperature, enters lung, kidney channel, astringe the lung, nourishing kidney, promote the production of body fluid, and receive antiperspirant, the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery because its nature and flavor acid.Select Magnetitum to be because its nature and flavor are pungent salty, flat, enter kidney, liver, lung meridian, have calming down the floating YANG to promote inspiration for relieving dyspnea, the function of tranquillizing the mind by relieving convulsion, controls the vertigo, Hiccough and deaf, dyspnea due to deficiency ， Jing Epilepsy, palpitation with a distress feeling.Select Cortex Cinnamomi to be because its property acrid-sweet flavor, heat, enters kidney, spleen, urinary bladder channel, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Lignum Aquilariae Resinatum is selected to be that temperature, enters kidney, spleen, stomach warp, have sending down the abnormal ascending QI warming middle-JIAO, the function of warming the kidney improving inspiration by invigorating kidney-QI, control QI rising in reverse order and pant because its nature and flavor are worked hard, vomiting singultus, abdominal distention, waist paint cold caused by deficiency, asthenia-cool of the large intestine, urine qi stranguria, man's cold sperm.Select Gecko to be because its nature and flavor are salty, flat, enter lung, kidney channel, have invigorating the lung and the kidney, the function of Dingchuan antitussive, controls asthenia, and consumptive lung disease is breathed heavily and coughed, and spitting of blood, quenches one's thirst, sexual impotence.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:

Radix Rehmanniae Preparata 12-16 Keshan Fructus Evodiae 13-18 gram of Radix Codonopsis 13-18 Keshan medicine 15-25 gram

Fructus Perillae 8-12 gram Poria 8-12 gram Fructus Schisandrae Chinensis 10-14 gram of Magnetitum 10-14 gram

Cortex Cinnamomi 2-6 gram Lignum Aquilariae Resinatum 2-6 gram Gecko 3-7 gram of Radix Glycyrrhizae 3-8 gram

Be preferably:

The Radix Rehmanniae Preparata 15 Keshan Fructus Evodiae 15 grams of Radix Codonopsis 15 Keshan medicines 20 grams

Fructus Perillae 10 grams of Poria 10 grams of Fructus Schisandrae Chinensis 12 grams of Magnetitums 12 grams

6 grams, Cortex Cinnamomi 4 grams of Lignum Aquilariae Resinatum 4 grams of Geckos 6 grams of Radix Glycyrrhizaes

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Radix Rehmanniae Preparata: get crude drug, steams to surperficial corvinus, takes out, when shining dry to eighty per cant, and section, dry;

2, Fructus Corni: clean, except removal core and impurity, dry;

3, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;

4, Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;

5, Fructus Perillae: dedust of winnowing with a dustpan is considered to be worth doing, cleans, dries;

6, Poria: be soaked in water, cleans, pulls out, and after vexed, section, dries;

7, Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;

8, Magnetitum: pick decontamination, smashes, and sieves;

9, Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;

10, Lignum Aquilariae Resinatum: outwash, is split into fritter, and the used time smashs to pieces or is ground into fine powder;

11, Gecko: removing bamboo chip, clips cephalopodium and squama, dices;

12, Radix Glycyrrhizae Preparata: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly stewing, puts in pot and fries to becoming buff with slow fire, till tack-free, take out to put and dries in the air, the cooked Mel 25-35 jin of every 100 jin of Radix Glycyrrhizaes.

Two, prepare

1, by the Radix Rehmanniae Preparata of described weight, Fructus Corni, Radix Codonopsis, Rhizoma Dioscoreae, Fructus Perillae, Poria, Fructus Schisandrae Chinensis, Magnetitum, Cortex Cinnamomi, Lignum Aquilariae Resinatum, Gecko, Radix Glycyrrhizae Preparata medicine, add water 10 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, within 30 minutes, filter with slow fire boiling again, obtain first time decoction liquor, first time decoction liquor is poured in container;

2, add water the medicinal residues of filtration 6 times amount, first boils with high heat, then within 20 minutes, filter with slow fire boiling, pours in container by second time decoction liquor;

3, twice decoction liquor is carried out mixing and stirring, be divided into 2 doses to take.

The Fructus Perillae therapeutic method to keep the adverse QI flowing downwards in prescription, expectorant, lung moistening, wide intestinal is monarch drug; Cortex Cinnamomi complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation, Poria eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, the two is ministerial drug, and three taste medicines play the therapeutic method to keep the adverse QI flowing downwards jointly, expectorant, lung moistening, wide intestinal, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation, the effect of eliminating dampness and diuresis, treatment pneumothorax effect is comprehensive, and with eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the wide intestinal of the therapeutic method to keep the adverse QI flowing downwards is that master can be effected a permanent cure, Magnetitum calming down the floating YANG to promote inspiration for relieving dyspnea, tranquillizing the mind by relieving convulsion is adjuvant drug, and Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, for making medicine, is take stopgap measures with all medicines of remainder.

Medicine of the present invention has warming the spleen and stomach, removing accumulated cold, eliminating dampness and diuresis, the wide intestinal of the therapeutic method to keep the adverse QI flowing downwards, lung moistening, and the function of promoting blood circulation, is used for the treatment of pneumothorax, short treating period, instant effect, non-relapse after healing, has no side effect.

Detailed description of the invention:

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention:

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept pneumothorax out-patient totally 32 examples for medical treatment.

2, diagnostic criteria

Classical symptom is sudden chest pain, then has uncomfortable in chest and dyspnea, and can irritantly cough.This chest pain is often acupuncture sample or the sample that lancinates, and the persistent period is very of short duration.Zest dry cough is because of caused by micro-tapping pleura.Most of onset is hurried, and pneumothorax amount is large, or the companion original pathological changes person of pulmonary, then tachypnea is obvious.

Patient often shows spiritual high-pressure, fear, dysphoria, tachypnea, sensation of asphyxia, cyanosis, perspiration, and has pulse thin and delicate and fast, and unconsciousness, stupor, even appear in the shock states such as blood pressure drops, skin are clammy.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 10 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.

4, efficacy assessment standard

Effective: pneumothorax transference cure, body constitution recovers normal, recovery from illness;

Take a turn for the better: pneumothorax symptom is clearly better, respiration rate is even, nonirritant pain, and body constitution is progressively recovered;

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy pneumothorax patient 32 example of the present invention, effective 27 examples of result, obvious effective rate is 84.37%, and take a turn for the better 3 examples, and improvement rate is 9.38%, and invalid 2 examples, total effective rate is 93.75%.

Claims

1. treat a medicine for pneumothorax, it is characterized in that: it is made up of the crude drug in following weight range:

Cortex Cinnamomi 2-6 gram Lignum Aquilariae Resinatum 2-6 gram Gecko 3-7 gram of Radix Glycyrrhizae 3-8 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

6 grams, Cortex Cinnamomi 4 grams of Lignum Aquilariae Resinatum 4 grams of Geckos 6 grams of Radix Glycyrrhizaes.

3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Radix Rehmanniae Preparata: get crude drug, steams to surperficial corvinus, takes out, when shining dry to eighty per cant, and section, dry;

(2) Fructus Corni: clean, except removal core and impurity, dry;

(3) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;

(4) Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;

(5) Fructus Perillae: dedust of winnowing with a dustpan is considered to be worth doing, cleans, dries;

(6) Poria: be soaked in water, cleans, pulls out, and after vexed, section, dries;

(7) Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;

(8) Magnetitum: pick decontamination, smashes, and sieves;

(9) Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;

(10) Lignum Aquilariae Resinatum: outwash, is split into fritter, and the used time smashs to pieces or is ground into fine powder;

(11) Gecko: removing bamboo chip, clips cephalopodium and squama, dices;

(12) Radix Glycyrrhizae Preparata: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed stewing, put in pot and fry to becoming buff with slow fire, till tack-free, take out to put and dry in the air, the cooked Mel 25-35 jin of every 100 jin of Radix Glycyrrhizaes;

(2) prepare

(1) by the Radix Rehmanniae Preparata of described weight, Fructus Corni, Radix Codonopsis, Rhizoma Dioscoreae, Fructus Perillae, Poria, Fructus Schisandrae Chinensis, Magnetitum, Cortex Cinnamomi, Lignum Aquilariae Resinatum, Gecko, Radix Glycyrrhizae Preparata medicine, add water 10 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, within 30 minutes, filter with slow fire boiling again, obtain first time decoction liquor, first time decoction liquor is poured in container;

(2) add water the medicinal residues of filtration 6 times amount, first boils with high heat, then within 20 minutes, filter with slow fire boiling, pours in container by second time decoction liquor;

(3) twice decoction liquor is carried out mixing and stirring, be divided into 2 doses to take.