CN104800390A - External applied pulvis for treating dental ulcer and preparation method - Google Patents
External applied pulvis for treating dental ulcer and preparation method Download PDFInfo
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Abstract
The invention discloses an external applied pulvis for treating dental ulcer, which is prepared by taking the following raw materials by weight part: 10 to 15 parts of borneol, 6 to 12 parts of compound of glauber-salt and liquorice, 15 to 20 parts of pearl powder, 4 to 10 parts of honeysuckle, 5 to 15 parts of fructus forsythiae, 2 to 9 parts of rehmanniae vaporata, 1 to 5 parts of folium isatidis, 1 to 5 parts of centella and 3 to 8 parts of vitamin C. The external applied pulvis has the effects in eliminating ozostomia and quickening the healing of an ulcer surface. Compared with the prior art, the external applied pulvis has the advantages of more obvious therapeutic effect, short treatment period and long-term use.
Description
Technical field
The invention discloses a kind of Dressed medicine powder, especially a kind of Dressed medicine powder and method for making for the treatment of oral ulcer.The invention belongs to traditional Chinese medicine field.
Background technology
Recurrent aphtha, also known as recurrent aphthous stomatitis, recurrent oral ulceration, recurrent aphtha, it is a kind of disease that in oral keritonocytes, sickness rate is the highest, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all accidentally can cause the generation of this disease, be apt to occur in lip, cheek, lingual margin etc., all can occur at any position of mucosa, but attached gingiva and hard palate are then rare completely in keratinization.Age of onset is generally between 10 ~ 30 years old, and women is more, all can occur throughout the year.Recurrent aphtha has self limiting, can spontaneous recovery in about 10 days.This disease has the features such as periodicity, recurrent and self limiting.Modern medicine is thought, first recurrent aphtha has very close relationship with immunity.Some patients are immunodeficiency, and some patients then show as autoimmune response; Next has relation with heredity, and in clinical, the morbidity of recurrent aphtha, has obvious Family inherited inclination, if father and mother one side or in many ways suffer from recurrent aphtha, their children are just easier than common people ill; In addition, the outbreak of recurrent aphtha, also relevant with some diseases or symptom, such as digestive system disease: gastric ulcer, duodenal ulcer, chronic or chronic persistent hepatitis, colitis etc., in addition monophagia, dyspepsia, generate heat, do not have enough sleep, overtired, operating pressure large, the change of menstrual cycle etc.Along with one or more factors active, alternately occur that immunity of organisms declines, cause the frequent outbreak of recurrent aphtha.
1. light-duty recurrent aphtha: responsive or occur needle point sample size or slightly large congested district from the beginning of lesion, namely forms diameter in a short time at about 2 ~ 4mm, circular or oval, sharply marginated shallow aphtha.Center micro-pits, surface is covered with the faint yellow pseudomembrane of one deck, and around ulcer, mucosa hyperemia is in blush shape, and it is not hard that its end lays one's hand on.Ulcer number is generally about 2 ~ 3.More violent burning pain is had after ulcer.Can spontaneous recovery gradually through about 7 ~ 10 days ulcer, do not stay cicatrix.But can recur again after the intermission different in size.Patient is very painful.2. herpesvirus type recurrent aphtha: also known as stomatitis type aphtha.This kind of is except ulcer is little, except number many (can reach 20 ~ 30), and all the other show similar to light-duty recurrent aphtha.KUIYANG SAN exists, widely distributed, and mucosa is obviously congested.To have an intense pain and with headache, heating, regional glandular enlargement etc.3. heavy recurrent aphtha: also known as Periadenitis mucosa periadenitis or periglandular aphthae is a type the most serious in various.The normal single generation of ulcer, more than 2 or 2 persons are rare.Be apt to occur in inside lip and bicker district mucosa.From the beginning of time ulcer identical with light-duty recurrent aphtha, but its diameter is extended to 1 ~ 2cm gradually, and to Deep Development to mucosa gland.Ulcer is aubergine or kermesinus, and edge is irregular, swells in flap, concavity, like " crater ".The end, is uneven, micro-firmly, in brief summary nodular, blush around ulcer, local has an intense pain and can accompany regional glandular enlargement, heating etc.The course of disease be everlasting the moon remaining more than.More afterwards leave over cicatrix, severe patient can formative tissue defect or deformity.
In the method for existing Chinese medicine oral ulcer, application publication number CN 102038815 A(application number 201010600379.1) patent discloses oral cavity ulcer powder, it is characterized in that: its crude drug is: Indigo Naturalis 8-12g, Borax (forging) 8-12g, Mannosum Kaki 16 ~ 24g, Dens Elephatis (roasting) 8-12g, Margarita 3-6g, Matrii Sulfas Exsiccatus 8-12 g, Concha (roasting) 2.4-3.2g, Resina Draconis 3-5g, Catechu 8-10g, Lasiosphaera Seu Calvatia 1.6-2.4g, Nidus Vespae (stir-fry) 2.4-4.2g, dried Alumen 3-5g, watermelon crystal 8-13g, Herba Asari 0.4-0.9g, Margarita powder brain 0.3-0.8g, Periostracum Serpentis (processing) 1.6-2.4g, Corium elephatis (roasting) 3-9g, Fructus Forsythiae 6-10g, Calculus Bovis 0.6-1g, steviosin 0.6-1g, Borneolum Syntheticum 0.15-0.3g, its manufacture method is: above-mentioned medical material is ground to form the fine powder by 250 eye mesh screens, prepare in proportion.Authorization Notice No. CN 102600365 B(application number 201210091494.X) patent discloses a kind of medicament for the treatment of oral ulcer, it is characterized in that, it is made up by weight of following bulk drugs: Herba Asari 10-20 part, Calyx seu Fructus physalis 20-30 part, Fructus Gardeniae 10-30 part, Margarita powder 20-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Fructus Evodiae 5-15 part, Indigo Naturalis 5-10 part, Radix Scutellariae 10-20 part and Lasiosphaera Seu Calvatia 10-20 part.
Along with the development of Chinese Chinese medicine, in treatment oral ulcer, it is little that people appreciate the side effect for the treatment of by Chinese herbs oral ulcer gradually, bear painful little advantage, and Chinese traditional treatment great attention to whole idea, pay attention to comprehensive control, pay attention to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, therapeutic effect demonstrates the advantage for the treatment of by Chinese herbs oral ulcer more.Chinese medicine has treatment oral ulcer, compensate qi and blood, supplements trace element needed for health, the special efficacy of hard masses softening and resolving, and persistent, treating both the principal and secondary aspects of a disease, has no side effect and efficacy consolidation, not easily to recur.
Summary of the invention
For the present situation of existing oral ulcer, an object of the present invention is the Dressed medicine powder providing treatment oral ulcer, has feature easy to operate, evident in efficacy, with low cost.Another object is just to provide the preparation method of above-mentioned Dressed medicine powder.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from: Borneolum Syntheticum 10-15 part, Matrii Sulfas Exsiccatus 6-12 part, Margarita powder 15-20 part, Flos Lonicerae 4-10 part, Fructus Forsythiae 5-15 part, Radix Rehmanniae Preparata 2-9 part, Folium Isatidis 1-5 part, Herba Centellae 1-5 part, vitamin C 3-8 part.
The Dressed medicine powder for the treatment of oral ulcer, preferred version is, takes off the primary raw material stating weight proportion and is prepared from: Borneolum Syntheticum 11-14 part, Matrii Sulfas Exsiccatus 7-11 part, Margarita powder 16-19 part, Flos Lonicerae 5-8 part, Fructus Forsythiae 7-13 part, Radix Rehmanniae Preparata 4-7 part, Folium Isatidis 2-4 part, Herba Centellae 2-4 part, vitamin C 5-7 part.
The Dressed medicine powder for the treatment of oral ulcer, preferred version is, takes off the primary raw material stating weight proportion and is prepared from: Borneolum Syntheticum 12 parts, Matrii Sulfas Exsiccatus 9 parts, Margarita powder 18 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, 5 parts, Radix Rehmanniae Preparata, Folium Isatidis 3 parts, Herba Centellae 3 parts, vitamin C 6 parts.
The preparation method of above-mentioned Dressed medicine powder, is characterized in that, step is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10-20 hour, is placed on food steamer, and big fire decocts to boiling, 10-20 minute is decocted at little fire, taking-up is placed in microwave oven, fries 2-6 minute, and grinding to form smalls, to cross 80-120 mesh sieve stand-by;
(3) be placed in marmite by Herba Centellae, add Herba Centellae weight 2-4 clear water doubly, decoct 20-30 minute, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing; little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling; decoct while stir with large ferrum spoon; after 3-7 to be mixed minute; cease fire; taking-up is placed on tile dries 1-2 hour with little fire, 50-60 DEG C of drying, bottles and obtains external pulvis.
Above-mentioned preparation method, step (2) is placed in crock, slightly stewing 13-18 hour (preferred, be placed in crock, slightly stewing 15 hours).
Above-mentioned preparation method, step (2) big fire decocts to boiling, decocts 13-18 minute, take out and be placed in microwave oven at little fire, fries 3-5 minute (preferred, big fire decocts to boiling, decocts 15 minutes, take out and be placed in microwave oven, fry 4 minutes at little fire).
Above-mentioned preparation method, step (3) adds Herba Centellae weight 2.5-3.5 clear water doubly (preferred, to add the clear water of Herba Centellae weight 3 times).
Above-mentioned preparation method, step (3) decocts 23-28 minute, filters (preferred, to decoct 25 minutes, filter).
Above-mentioned preparation method, step (4) decocts and stirs with large ferrum spoon, after 4-6 to be mixed minute (preferred, to decoct while stir, after 5 minutes to be mixed with large ferrum spoon).
Above-mentioned preparation method, step (4) is taken out to be placed on tile and is dried 1.3-1.8 hour with little fire, 23-28 DEG C of drying (preferred, to take out to be placed on tile and dry 1.5 hours, 55 DEG C of dryings with little fire).
Using method: for making the present invention reach optimum therapeuticing effect, first gargle with clear water, then, by Dressed medicine powder, spreads upon the place of ulcer, and one for several times, at every turn in right amount.
The pharmacological effect of each crude drug is respectively:
Borneolum Syntheticum: Borneolum Syntheticum, has another name called sheet brain, Fructus Citri tangerinae sheet, Blumeae preparatum Tabellae, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., is through steam distillation and recrystallization and obtaining by Compositae Herba Blumeae Balsamiferae stem and leaf or canella Borneolum Syntheticum Camphor tree branch and leaf.Also useful Oleum Terebinthinae obtains through a series of chemical method technique.It can be used for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, to swell and ache for skin infection, and do not hold back after bursting, Borneolum Syntheticum acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has refreshment of having one's ideas straightened out, and the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, and heat-damp in summer hoodwinks key clearly, and sore throat is deaf, and aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Matrii Sulfas Exsiccatus: main component is anhydrous sodium sulfate Na2SO4.Be that Mirabilitum (Na2SO4.10H2O) dehydration is made, due to the place of production and refinement method difference, contained field trash is also different, and common person is calcium sulfate (CaSO4), iron sulfate Fe2 (SO4) 3, potassium sulfate (K2SO4).There is purging heat to relax the bowels; Hard masses softening and resolving; Heat-clearing and toxic substances removing; Lung heat clearing expelling summer-heat; Effect of removing food stagnancy stomach function regulating.Primary treatment excess-heat stagnates; Constipation; Conjunctival congestion and swelling pain; Pharyngeal swelling aphtha; Swollen ulcer drug.
Margarita powder: the Organic substance [3] in Margarita is containing 17 seed amino acids such as Aspartic Acid, threonine, serine, glutamic acid, glycine, alanine, cystine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, histidine, arginine, proline.In addition, also containing 30 various trace elements, taurine, abundant vitamin, peptide class.
To calm the nerves arresting convulsion, heat clearing away YIN nourishing, improving eyesight, removing toxic substances.1. relieving palpitation arresting convulsion, is applicable to palpitation with fear palpitation with a distress feeling, epilepsy infantile convulsion.2. liver heat removing is except nebula improving eyesight, with controlling the ophthalmic diseases such as conjunctival congestion and swelling pain, pterygium, and many externals.3. restrain granulation promoting, be applicable to that throat rots, aphtha of the mouth and tongue, ulcer do not close up for a long time, should external, tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, removing toxic substances and promoting granulation.Control palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, and the raw cataracta of order, skin infection does not close up for a long time.
Flos Lonicerae: modern study proves, Flos Lonicerae contains chlorogenic acid, the pharmacological components such as luteolin glycosides, to Hemolytic streptococcus, the various pathogens such as staphylococcus aureus and upper respiratory tract infection Causative virus etc. have stronger restraint, in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, respiratory tract infection can be used for the treatment of with other medicines compatibility, bacillary dysentery, acute urinary, hypertension etc. more than 40 plant disease, Flos Lonicerae is cold in nature, sweet in the mouth, enter lung, the heart, stomach warp, there is heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treats effect of wind, cure mainly disease under distension, epidemic febrile disease is generated heat, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.。
Fructus Forsythiae: enter the heart, liver, gallbladder, stomach, three burnt, large intestine the six channels.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Radix Rehmanniae Preparata: Radix Rehmanniae sweet-bitter flavor, cold in nature and enter blood system, clearing away heat and cooling blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.Radix Rehmanniae Preparata sweet in the mouth, property are flat and enter blood system, function nourishing YIN and supplementing blood, vital essence replenishing and marrow benifiting.Control deficiency of YIN insufficiency of blood, the hollow institute of brains waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency extremely, pass out semen, metrorrhagia, menoxenia, quench one's thirst, frequency of micturition, deaf, blurred vision, palpitation and insomnia, forgetful, night sweat etc., Radix Rehmanniae Preparata, sweet, tepor, can nourishing YIN and supplementing the kidney, replenishing essence, cure mainly shallow complexion caused by blood deficiency, dizzy cardiopalmus; The soreness of the waist and knees of deficiency of kidney-essence, have a dizzy spell, early whitening of beard and hair; The binocular dryness of deficiecny of liver-YIN, blurring of vision.And Radix Angelicae Sinensis its root medicinal, merit is being enriched blood and blood, cures mainly menoxenia, dizziness due to deficiency of blood, and skin infection is swollen waits disease.
Folium Isatidis: bitter in the mouth, cold in nature.Gui Jing returns liver, the heart, stomach, spleen channel.Effect heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Cure mainly for the high hot excessive thirst of calentura; Coma; Macule; Spit blood; Epistaxis; Jaundice; Dysentery; Erysipelas; Sore throat; Aphtha; Mumps.
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.
Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Vitamin C: vitamin C is that antibody and collagen are formed, tissue repairing's (comprising some redox), phenylalanine, tyrosine, the metabolism of folic acid, ferrum, the utilization of carbohydrate, fat, the synthesis of protein, maintain immunologic function, hydroxylation and hydroxytryptamine, keep the complete of blood vessel, promote that the institutes such as nonheme iron absorption are required, vitamin C also has antioxidation simultaneously, free radical resisting, the formation of restraint of tyrosinase, thus reach whitening, effect of light speckle, ascorbic acid deficiency, lose its most important function, namely the hydroxylation procedures of hydroxyproline and lysine can not carry out smoothly, collagen protein synthesis is obstructed, cause scorbutic generation.Early manifestation is tired, asthenia, and swelling and aching of gum, hemorrhage, wound healing is slow, can occur visceral hemorrhage and threat to life time serious.
Compared with prior art, technical advantage of the present invention is embodied in:
1, the present invention's medical material used does not have toxicity, and the health mechanism for sufferer can not cause damage, and audient crowd is wide, and applicable child and old people take.
2, bright the used medical material relative inexpensiveness of this law, compared with prior art the bright obtained Dressed medicine powder cost of this law more
Add cheap.
3, therapeutic effect of the present invention is compared to prior art, and therapeutic effect is more obvious, and treatment cycle is short, does not have obvious sequela, can life-time service.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Borneolum Syntheticum 10 parts, Matrii Sulfas Exsiccatus 6 parts, Margarita powder 15 parts, Flos Lonicerae 4 parts, Fructus Forsythiae 5 parts, 2 parts, Radix Rehmanniae Preparata, Folium Isatidis 1 part, Herba Centellae 1 part, vitamin C 3 parts.
The Dressed medicine powder preparation process for the treatment of oral ulcer is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10 hours, be placed on food steamer, big fire decocts to boiling, decoct 10 minutes at little fire, taking-up is placed in microwave oven, fries 2 minutes, and grinding to form smalls, to cross 80 mesh sieves stand-by;
(3) be placed in marmite by Herba Centellae, add the clear water of Herba Centellae weight 2 times, decoct 20 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling, decocts and stirs with large ferrum spoon; after 3 minutes to be mixed, cease fire, take out to be placed on tile and dry 1 hour with little fire; 50 DEG C of dryings, bottle and obtain external pulvis.
model case onepoplar XX, man, 32 years old.Suffer from oral ulcer, oral ulcer, patient does not too pay close attention to oral cavity ulcerative conditions, do not seek medical advice in time, along with oral ulcer is serious all the more, there is the symptom of halitosis in sufferer, with dense implication when speaking, with rotten-egg odour, had a strong impact on sufferer and other people normal talk, sufferer then arrives hospital and seeks medical advice, while treatment oral ulcer, under the suggestion of doctor, use the Dressed medicine powder obtained by this enforcement 1.
Use Dressed medicine powder obtained by the present embodiment 1, use 2 days, sufferer implication is obviously thin out, and rotten-egg odour alleviates, and ulcer surface has not ached, and continues use after 3 days, and sufferer implication recovers normal, and rotten-egg odour disappears, and ulcer surface is fully recovered.
embodiment 2the Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Borneolum Syntheticum 15 parts, Matrii Sulfas Exsiccatus 12 parts, Margarita powder 20 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 15 parts, 9 parts, Radix Rehmanniae Preparata, Folium Isatidis 5 parts, Herba Centellae 5 parts, vitamin C 8 parts.
The Dressed medicine powder preparation process for the treatment of oral ulcer is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 20 hours, be placed on food steamer, big fire decocts to boiling, decoct 20 minutes at little fire, taking-up is placed in microwave oven, fries 6 minutes, and grinding to form smalls, to cross 120 mesh sieves stand-by;
(3) be placed in marmite by Herba Centellae, add the clear water of Herba Centellae weight 4 times, decoct 30 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling, decocts and stirs with large ferrum spoon; after 7 minutes to be mixed, cease fire, take out to be placed on tile and dry 2 hours with little fire; 60 DEG C of dryings, bottle and obtain external pulvis.
embodiment 3the Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Borneolum Syntheticum 11 parts, Matrii Sulfas Exsiccatus 7 parts, Margarita powder 16 parts, Flos Lonicerae 5 parts, Fructus Forsythiae 7 parts, 4 parts, Radix Rehmanniae Preparata, Folium Isatidis 2 parts, Herba Centellae 2 parts, vitamin C 5 parts.
The Dressed medicine powder preparation process for the treatment of oral ulcer is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 13 hours, be placed on food steamer, big fire decocts to boiling, decoct 13 minutes at little fire, taking-up is placed in microwave oven, fries 3 minutes, and grinding to form smalls, to cross 90 mesh sieves stand-by;
(3) be placed in marmite by Herba Centellae, add the clear water of Herba Centellae weight 2.5 times, decoct 23 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing; little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling; decoct while stir with large ferrum spoon; after 4 minutes to be mixed; cease fire; taking-up is placed on tile dries 1.3 hours with little fire, 53 DEG C of dryings, bottles and obtains external pulvis.
typical case two: Feng XX, female, 26 years old, the business department manager of certain company, like pungent food, suffer from oral ulcer, oral ulcer is not cured for a long time, and sufferer too seriously causes the symptom occurring halitosis due to oral ulcer, oral ulcer disease is aggravated, and with implication, implication distributes rotten stench.Seek medical advice to hospital, under the suggestion of doctor of traditional Chinese medicine, employ Dressed medicine powder obtained in the present embodiment 3.
Use the Dressed medicine powder obtained by this enforcement 3, use 1 day, implication obviously alleviates, and continues use 3 days, and implication recovers normal, and oral ulcer makes moderate progress, and sufferer self-induction therapeutic effect is good.
embodiment 4the Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from (getting 25g for every part): Borneolum Syntheticum 14 parts, Matrii Sulfas Exsiccatus 11 parts, Margarita powder 19 parts, Flos Lonicerae 8 parts, Fructus Forsythiae 13 parts, 7 parts, Radix Rehmanniae Preparata, Folium Isatidis 4 parts, Herba Centellae 4 parts, vitamin C 7 parts.
The Dressed medicine powder preparation process for the treatment of oral ulcer is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 18 hours, be placed on food steamer, big fire decocts to boiling, decoct 18 minutes at little fire, taking-up is placed in microwave oven, fries 5 minutes, and grinding to form smalls, to cross 110 mesh sieves stand-by;
(3) be placed in marmite by Herba Centellae, add the clear water of Herba Centellae weight 3.5 times, decoct 28 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing; little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling; decoct while stir with large ferrum spoon; after 6 minutes to be mixed; cease fire; taking-up is placed on tile dries 1.8 hours with little fire, 58 DEG C of dryings, bottles and obtains external pulvis.
embodiment 5the Dressed medicine powder for the treatment of oral ulcer, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Borneolum Syntheticum 12 parts, Matrii Sulfas Exsiccatus 9 parts, Margarita powder 18 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, 5 parts, Radix Rehmanniae Preparata, Folium Isatidis 3 parts, Herba Centellae 3 parts, vitamin C 6 parts.
The Dressed medicine powder preparation process for the treatment of oral ulcer is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 15 hours, be placed on food steamer, big fire decocts to boiling, decoct 15 minutes at little fire, taking-up is placed in microwave oven, fries 2-64 minute, and grinding to form smalls, to cross 100 mesh sieves stand-by;
(3) be placed in marmite by Herba Centellae, add the clear water of Herba Centellae weight 3 times, decoct 25 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing; little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling; decoct while stir with large ferrum spoon; after 5 minutes to be mixed; cease fire; taking-up is placed on tile dries 1.5 hours with little fire, 55 DEG C of dryings, bottles and obtains external pulvis.
test example 1:the clinical practice of the Dressed medicine powder of embodiment 5 gained treatment oral ulcer: in January ,-2015 in July, 2013,400 routine patients are screened in 5 hospitals, max age 65 years old, minimal ages 10 years old, all suffer from because of oral ulcer, sufferer is divided into two groups at random, experimental group 200 people, matched group 200 people, experimental group uses the Dressed medicine powder obtained by this enforcement 5, and matched group uses other medicines, observe 6 days time limits, test and the symptom of patient was comprehensively checked in first 1 day, regularly check inquiry patient body situation and impression during experiment, and make a record.Effective: malaise symptoms alleviates or partial disappearance.Cure: malaise symptoms disappears, and without recurrence.Invalid: malaise symptoms is unchanged or recur.Result is as shown in the table:
Prove through clinical trial, use Dressed medicine powder of the present invention compared with the medicine of other treatment oral ulcer, treatment means is more comprehensive thoroughly, has no side effect between the operating period, while treatment oral ulcer, the symptom such as pain, halitosis brought by oral ulcer can be alleviated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 99%.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat the Dressed medicine powder of oral ulcer, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Borneolum Syntheticum 10-15 part, Matrii Sulfas Exsiccatus 6-12 part, Margarita powder 15-20 part, Flos Lonicerae 4-10 part, Fructus Forsythiae 5-15 part, Radix Rehmanniae Preparata 2-9 part, Folium Isatidis 1-5 part, Herba Centellae 1-5 part, vitamin C 3-8 part.
2. the Dressed medicine powder for the treatment of oral ulcer according to claim 4, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Borneolum Syntheticum 11-14 part, Matrii Sulfas Exsiccatus 7-11 part, Margarita powder 16-19 part, Flos Lonicerae 5-8 part, Fructus Forsythiae 7-13 part, Radix Rehmanniae Preparata 4-7 part, Folium Isatidis 2-4 part, Herba Centellae 2-4 part, vitamin C 5-7 part.
3. the Dressed medicine powder for the treatment of oral ulcer according to claim 4, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Borneolum Syntheticum 12 parts, Matrii Sulfas Exsiccatus 9 parts, Margarita powder 18 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, 5 parts, Radix Rehmanniae Preparata, Folium Isatidis 3 parts, Herba Centellae 3 parts, vitamin C 6 parts.
4. the preparation method of the Dressed medicine powder for the treatment of oral ulcer according to claim 4, is characterized in that: step is as follows:
(1) by Borneolum Syntheticum, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae Preparata and Folium Isatidis are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10-20 hour, is placed on food steamer, and big fire decocts to boiling, 10-20 minute is decocted at little fire, taking-up is placed in microwave oven, fries 2-6 minute, and grinding to form smalls, to cross 80-120 mesh sieve stand-by;
(3) be placed in marmite by Herba Centellae, add Herba Centellae weight 2-4 clear water doubly, decoct 20-30 minute, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing; little fire decocts and add Matrii Sulfas Exsiccatus, Margarita powder and vitamin C to boiling; decoct while stir with large ferrum spoon; after 3-7 to be mixed minute; cease fire; taking-up is placed on tile dries 1-2 hour with little fire, 50-60 DEG C of drying, bottles and obtains external pulvis.
5. preparation method according to claim 4, is characterized in that: step (2) is placed in crock, slightly stewing 13-18 hour (preferred, be placed in crock, slightly stewing 15 hours).
6. preparation method according to claim 4, it is characterized in that: step (2) big fire decocts to boiling, 13-18 minute is decocted at little fire, taking-up is placed in microwave oven, (preferred, big fire decocts to boiling, decocts 15 minutes at little fire to fry 3-5 minute, taking-up is placed in microwave oven, fries 4 minutes).
7. preparation method according to claim 4, is characterized in that: step (3) adds Herba Centellae weight 2.5-3.5 clear water doubly (preferred, to add the clear water of Herba Centellae weight 3 times).
8. preparation method according to claim 4, is characterized in that: step (3) decocts 23-28 minute, filters (preferred, to decoct 25 minutes, filter).
9. preparation method according to claim 4, is characterized in that: step (4) decocts and stirs with large ferrum spoon, after 4-6 to be mixed minute (preferred, to decoct while stir, after 5 minutes to be mixed with large ferrum spoon).
10. preparation method according to claim 4, is characterized in that: step (4) is taken out to be placed on tile and dried 1.3-1.8 hour with little fire, 23-28 DEG C of drying (preferred, to take out to be placed on tile and dry 1.5 hours, 55 DEG C of dryings with little fire).
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| CN105477688A (en) * | 2015-12-08 | 2016-04-13 | 安徽天瑞塑业有限公司 | Brush bristle improving oral ulcers and preparation process thereof |
| CN111374913A (en) * | 2018-12-29 | 2020-07-07 | 天津市慧珍科技有限公司 | Oral cleaning solution and preparation method thereof |
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Application publication date: 20150729 |