CN105477688A - Brush bristle improving oral ulcers and preparation process thereof - Google Patents
Brush bristle improving oral ulcers and preparation process thereof Download PDFInfo
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- CN105477688A CN105477688A CN201510920360.8A CN201510920360A CN105477688A CN 105477688 A CN105477688 A CN 105477688A CN 201510920360 A CN201510920360 A CN 201510920360A CN 105477688 A CN105477688 A CN 105477688A
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- brush silk
- oral ulcer
- preparation technology
- brush bristle
- chitosan
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
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Abstract
The invention discloses a brush bristle improving oral ulcers and a preparation process thereof. The surface of the brush bristle is coated with an oral ulcer film and comprises an inner structural layer and an outer structural layer, wherein ingredients of the inner layer include water-soluble chitosan, sesame oil and a humectant, ingredients of the outer layer include Alumen Siccanus, Flos Lonicerae, Pulvis Margarita and Borneolum Syntheticum. The preparation process is simple and low in cost, the brush bristle can inhibit germs and promote healing of oral ulcers, the oral ulcer film is soft and good in affinity and can attach to the surface of the brush bristle for a long time, and the brush bristle is lower in production cost, safe and harmless and is effective in treating oral ulcers.
Description
Technical field
The present invention relates to brush silk field, specifically a kind of brush silk and preparation technology thereof improving oral ulcer.
Background technology
Oral ulcer is a kind of common oral keritonocytes, is a kind of shallow and little, circular or avette ulcer, and sickness rate is high and very easily recur.Now be used for the treatment of oral ulcer dosage form and mainly contain tablet, liniment, membrane.Tablet is comparatively hard, comparatively large to wound surface mechanical stimulus when sticking, and can not use by ulcer surface size.Liniment consumption is few, and active ingredient is few, weak curative effect.Membrane is softer, and less to wound surface zest, preparation method is simple.
The present invention on the basis of existing technology, to brush silk surface-coated KOUQIANG KUIYANG MO, makes to contact KOUQIANG KUIYANG MO for a long time in the daily life of gargling, effectively inhibits pathogenic bacteria, play good therapeutic effect to the treatment of oral ulcer.
Summary of the invention
The present invention aims to provide a kind of the brush silk and the preparation technology thereof that improve oral ulcer.
For realizing described object, the invention provides following technical scheme:
A kind of brush silk and preparation technology thereof improving oral ulcer, described brush silk surface is coated with KOUQIANG KUIYANG MO, it is made up of inside and outside double-layer structure, and wherein the composition of internal layer is water-soluble chitosan, Oleum Sesami and wetting agent, and outer field composition is dried Alumen, Flos Lonicerae, Margarita powder, Borneolum Syntheticum.
Improve brush silk and the preparation technology thereof of oral ulcer, comprise the following steps:
(1) raw material of above-mentioned KOUQIANG KUIYANG MO is fully mixed with KOUQIANG KUIYANG MO;
(2) pending brush silk surface is carried out clean, smooth process;
(3) with amino air-tightness resin, sealing treatment is carried out to brush silk surface;
(4) brush silk is placed in cleans containing pickle or sig water, dry;
(5) implement Vacuum Deposition KOUQIANG KUIYANG MO on the surface of the brush silk of drying, make KOUQIANG KUIYANG MO be attached at brush silk surface, form the oral ulcer thin film of continuous uniform.
Described inner component forms by following parts by weight proportioning, water-soluble chitosan 20-30 part, Oleum Sesami 15-25 part and wetting agent 40-45 part.
Described outer field composition forms by following parts by weight proportioning, dried Alumen 18-25 part, Flos Lonicerae 20-25 part, Margarita powder 10-15 part, Borneolum Syntheticum 30-40 part.
Described water-soluble chitosan is any one or multiple mixture in carboxymethyl chitosan, chitosan quaternary ammonium salt, hydroxyethyl chitosan.
Described wetting agent is any one or a few mixture in glycerol, propylene glycol, sorbitol.
Described amino air-tightness resin is melamine resin, Lauxite or tripolycyanamide and carbamide and formaldehyde cocondensation resin adhesive.
Compared with prior art, the invention has the beneficial effects as follows: present invention process is simple, with low cost, pathogenic bacteria can be suppressed, promote the healing of oral ulcer, KOUQIANG KUIYANG MO of the present invention is soft, affinity is good, the surface being attached at brush silk that can be limited for a long time, save production cost, safe and harmless.
Detailed description of the invention
See below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
A kind of brush silk and preparation technology thereof improving oral ulcer, described brush silk surface is coated with KOUQIANG KUIYANG MO, it is made up of inside and outside double-layer structure, and wherein the composition of internal layer is water-soluble chitosan, Oleum Sesami and wetting agent, and outer field composition is dried Alumen, Flos Lonicerae, Margarita powder, Borneolum Syntheticum.
Improve brush silk and the preparation technology thereof of oral ulcer, comprise the following steps:
(1) raw material of above-mentioned KOUQIANG KUIYANG MO is fully mixed with KOUQIANG KUIYANG MO;
(2) pending brush silk surface is carried out clean, smooth process;
(3) with amino air-tightness resin, sealing treatment is carried out to brush silk surface;
(4) brush silk is placed in cleans containing pickle or sig water, dry;
(5) implement Vacuum Deposition KOUQIANG KUIYANG MO on the surface of the brush silk of drying, make KOUQIANG KUIYANG MO be attached at brush silk surface, form the oral ulcer thin film of continuous uniform.
Described inner component forms by following parts by weight proportioning, water-soluble chitosan 20-30 part, Oleum Sesami 15-25 part and wetting agent 40-45 part.
Described outer field composition forms by following parts by weight proportioning, dried Alumen 18-25 part, Flos Lonicerae 20-25 part, Margarita powder 10-15 part, Borneolum Syntheticum 30-40 part.
Described water-soluble chitosan is any one or multiple mixture in carboxymethyl chitosan, chitosan quaternary ammonium salt, hydroxyethyl chitosan.
Described wetting agent is any one or a few mixture in glycerol, propylene glycol, sorbitol.
Described amino air-tightness resin is melamine resin, Lauxite or tripolycyanamide and carbamide and formaldehyde cocondensation resin adhesive.
To those skilled in the art, obviously the invention is not restricted to the details of described one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of described explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (7)
1. one kind is improved brush silk and the preparation technology thereof of oral ulcer, it is characterized in that, described brush silk surface is coated with KOUQIANG KUIYANG MO, it is made up of inside and outside double-layer structure, wherein the composition of internal layer is water-soluble chitosan, Oleum Sesami and wetting agent, and outer field composition is dried Alumen, Flos Lonicerae, Margarita powder, Borneolum Syntheticum.
2. improve brush silk and the preparation technology thereof of oral ulcer, it is characterized in that, comprise the following steps:
(1) raw material of above-mentioned KOUQIANG KUIYANG MO is fully mixed with KOUQIANG KUIYANG MO;
(2) pending brush silk surface is carried out clean, smooth process;
(3) with amino air-tightness resin, sealing treatment is carried out to brush silk surface;
(4) brush silk is placed in cleans containing pickle or sig water, dry;
(5) implement Vacuum Deposition KOUQIANG KUIYANG MO on the surface of the brush silk of drying, make KOUQIANG KUIYANG MO be attached at brush silk surface, form the oral ulcer thin film of continuous uniform.
3. a kind of brush silk and preparation technology thereof improving oral ulcer according to claim 1, is characterized in that: described inner component forms by following parts by weight proportioning, water-soluble chitosan 20-30 part, Oleum Sesami 15-25 part and wetting agent 40-45 part.
4. a kind of brush silk and preparation technology thereof improving oral ulcer according to claim 1, it is characterized in that: described outer field composition forms by following parts by weight proportioning, dried Alumen 18-25 part, Flos Lonicerae 20-25 part, Margarita powder 10-15 part, Borneolum Syntheticum 30-40 part.
5. a kind of brush silk and preparation technology thereof improving oral ulcer according to claim 1, is characterized in that: described water-soluble chitosan is any one or multiple mixture in carboxymethyl chitosan, chitosan quaternary ammonium salt, hydroxyethyl chitosan.
6. a kind of brush silk and preparation technology thereof improving oral ulcer according to claim 1, is characterized in that: described wetting agent is any one or a few mixture in glycerol, propylene glycol, sorbitol.
7. a kind of brush silk and preparation technology thereof improving oral ulcer according to claim 1 and 2, is characterized in that: described amino air-tightness resin is melamine resin, Lauxite or tripolycyanamide and carbamide and formaldehyde cocondensation resin adhesive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510920360.8A CN105477688A (en) | 2015-12-08 | 2015-12-08 | Brush bristle improving oral ulcers and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510920360.8A CN105477688A (en) | 2015-12-08 | 2015-12-08 | Brush bristle improving oral ulcers and preparation process thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105477688A true CN105477688A (en) | 2016-04-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510920360.8A Pending CN105477688A (en) | 2015-12-08 | 2015-12-08 | Brush bristle improving oral ulcers and preparation process thereof |
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| Country | Link |
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| CN (1) | CN105477688A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346120A (en) * | 2020-05-06 | 2020-06-30 | 秦宜梅 | Chinese herbal medicine ointment for treating intractable ulceration wound and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405483A (en) * | 2013-08-13 | 2013-11-27 | 上海美宝生命科技有限公司 | Oral ulcer membrane |
| CN103726011A (en) * | 2012-10-12 | 2014-04-16 | 无锡慧明电子科技有限公司 | Decorative plastic surface vacuum-coating film preparation method |
| CN104800390A (en) * | 2015-05-11 | 2015-07-29 | 王道欣 | External applied pulvis for treating dental ulcer and preparation method |
| CN105030558A (en) * | 2008-02-08 | 2015-11-11 | 高露洁-棕榄公司 | COMPOSITIONS AND DEVICES FOR DELIVERING a basic amino acid to an oral |
-
2015
- 2015-12-08 CN CN201510920360.8A patent/CN105477688A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105030558A (en) * | 2008-02-08 | 2015-11-11 | 高露洁-棕榄公司 | COMPOSITIONS AND DEVICES FOR DELIVERING a basic amino acid to an oral |
| CN103726011A (en) * | 2012-10-12 | 2014-04-16 | 无锡慧明电子科技有限公司 | Decorative plastic surface vacuum-coating film preparation method |
| CN103405483A (en) * | 2013-08-13 | 2013-11-27 | 上海美宝生命科技有限公司 | Oral ulcer membrane |
| CN104800390A (en) * | 2015-05-11 | 2015-07-29 | 王道欣 | External applied pulvis for treating dental ulcer and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 池永胜 等: "真空镀敷陶瓷涂层的原理和应用", 《模具技术》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346120A (en) * | 2020-05-06 | 2020-06-30 | 秦宜梅 | Chinese herbal medicine ointment for treating intractable ulceration wound and preparation method thereof |
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Application publication date: 20160413 |
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