CN104800257B - A kind of ripe pseudo-ginseng of vinegar system and its processing procedure and application - Google Patents

A kind of ripe pseudo-ginseng of vinegar system and its processing procedure and application Download PDF

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CN104800257B
CN104800257B CN201410035656.7A CN201410035656A CN104800257B CN 104800257 B CN104800257 B CN 104800257B CN 201410035656 A CN201410035656 A CN 201410035656A CN 104800257 B CN104800257 B CN 104800257B
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ginseng
pseudo
vinegar
processing procedure
ripe
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CN104800257A (en
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陈斌
张海
王佳
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Snow Ruian Chengdu Health Control Co Ltd
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Snow Ruian Chengdu Health Control Co Ltd
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Abstract

The present invention relates to a kind of new concocting method of pseudo-ginseng, belong to tcm field.The invention discloses a kind of ripe pseudo-ginseng of vinegar system and its processing procedure and application, its processing procedure includes the following steps:A, using pseudo-ginseng as raw material, the vinegar immersion of 0.15 3 times of amounts is added in terms of pseudo-ginseng weight;B, the pseudo-ginseng after step A immersions is taken to be steamed with steam;C, drying.The method can significantly improve the content of notoginseng polysaccharide and radix notoginseng flavones.

Description

A kind of ripe pseudo-ginseng of vinegar system and its processing procedure and application
Technical field
The present invention relates to a kind of new concocting method of pseudo-ginseng, the especially processing procedure of the ripe pseudo-ginseng of vinegar system and application, belongs to In tcm field.
Background technology
Pseudo-ginseng is the drying root and rhizome of panax araliaceae plant, belongs to rare Chinese medicine, is distributed in Yunnan, Guangxi etc. Ground, has a dissipate stasis of blood hemostasis, the effect of detumescence ding-tong, tcm clinical practice is usually used in spitting blood, spits blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, traumatic hemorrhage, chest Ventral spine pain, tumbling and swelling.
The prepared slices of Chinese crude drugs pass through the medicine used after Preparation process for clinical treatment, the pseudo-ginseng of tcm clinical practice application for Chinese medicine Medicine materical crude slice is divided into two kinds of processed products of raw sangqi ginseng and ripe pseudo-ginseng.Raw sangqi ginseng is longer than promoting blood circulation and removing blood stasis, detumescence ding-tong, cures mainly wound, pain, blood Card etc., ripe pseudo-ginseng are longer than blood-nourishing, and QI invigorating, strengthening by means of tonics, cures mainly weak wait of deficiency of vital energy blood and demonstrate,prove.
Traditional concocting method of ripe pseudo-ginseng is steams, during steaming, the main component in raw sangqi ginseng(Ginsenoside Rg1、Rb1, Rd, Re and Panax Notoginseng saponin R1)New saponin constituent is progressively converted into, is respectively ginsenoside 20 (S)-Rh1、20 (R)-Rh1、Rk3、Rh4、20(S)-Rg3、20(R)-Rg3、Rk1And Rg5
The common of ripe pseudo-ginseng steams that the process time is long, temperature is high, energy consumption is big, management difficulty is big, is its shortcoming.It is modern Process and learn in research, technique is steamed to pseudo-ginseng and is specially studied, such as Chinese patent application 200610010771.4, a kind of pseudo-ginseng Processing method and products thereof provides one kind and steams pseudo-ginseng.
However, steamed by tradition and in the prior art two other in pseudo-ginseng that existing concocting method obtains it is important into Divide the content of notoginseng polysaccharide and general flavone relatively low, seriously compromise the medicinal efficacy of pseudo-ginseng.
The content of the invention
The object of the present invention is to provide a kind of new processed product of pseudo-ginseng, the i.e. ripe pseudo-ginseng of vinegar system.
The object of the present invention is to provide application of the ripe pseudo-ginseng of vinegar system in liver protection and/or liver-protecting medicine is prepared.
The object of the present invention is to provide a kind of new processing procedure of pseudo-ginseng, include the following steps:
A, using pseudo-ginseng as raw material, the 0.15-3 times of vinegar measured immersion is added in terms of pseudo-ginseng weight, soaking conditions are:5-30 DEG C, When 1-24 is small;
B, the pseudo-ginseng after step A immersions is taken to be steamed with steam, the condition of steaming is:Pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, when the time is 2-48 small;
C, drying.
As one of preferable technical solution, the pseudo-ginseng in step A can make pulverization process before vinegar immersion, because pseudo-ginseng Medicinal material is bull tuberous root, and vinegar is more easy to absorb pickle after beating powder, preferably plays the effect of vinegar.
As one of preferable technical solution, dried pseudo-ginseng is steamed in step C and carries out pulverization process again, after crushing Granularity can be controlled in coarse granularity, e.g., crosses -40 mesh sieve of 10 mesh.
Wherein, the vinegar described in step A includes rice vinegar, aromatic vinegar, mature vinegar, light-coloured vinegar, acetin.The rice vinegar is using rice as original Material, is led to traditional handicraft;The aromatic vinegar is made by primary raw material of glutinous rice;The mature vinegar is old by primary raw material of sorghum Wine forms;The light-coloured vinegar is artificial synthesized common light-coloured vinegar;The acetin is that edible glacial acetic acid dilution forms.
The number of degrees that above-mentioned vinegar uses include 1-9 degree.The number of degrees of vinegar are preferably 6 degree of vinegars, 9 degree of rice vinegars, acetin(2-3 Degree).
Further, the 0.15-1 times of vinegar measured immersion is added in step A in terms of pseudo-ginseng weight.
Further, soaking conditions are in step A:5-30 DEG C, when 1-12 is small.
Further, step B steams condition and is:Pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, time 2-24 Hour.
When step C is dried, it is 7%-13% to preferably control medicinal material moisture.It is preferred that drying condition is as follows:Drying temperature For 40-100 DEG C, when drying time is 3-8 small.
Drying mode used in the present invention includes microwave drying, naturally dry, heated-air circulation oven drying or superconductive energy-saving The various drying means known in the art such as dry.
As one of preferable technical solution, natural cooling after the ripe notoginseng drying of vinegar system, packaging.
Processing procedure prepares the ripe pseudo-ginseng of vinegar system of gained, the wherein content of notoginseng polysaccharide and radix notoginseng flavones according to the present invention Significantly improve:The content of notoginseng polysaccharide increases 80%-200% than increasing 1.5-3 times in raw sangqi ginseng, than common steam in pseudo-ginseng.Three The content of seven general flavones increases 100%-300% than increasing 2-4 times in raw sangqi ginseng, than common steam in pseudo-ginseng.In addition, increase after vinegar system The effect for " entering Liver Channel " in its strong theory of traditional Chinese medical science, has the function that liver protection, protect liver.
The method is easy, efficient, easily operated, and of low cost, compared with tradition steams ripe pseudo-ginseng concocting method, reaches Steaming time needed for identical saponin content is greatly decreased, and can significantly improve the content of notoginseng polysaccharide and radix notoginseng flavones, section The about energy, is highly suitable to be applied for mass producing.It can obtain extensively should in new drug development, health food innovation area at the same time With.
Beneficial effect
The present invention uses vinegar system+Powder Made by Steamed Method, and the processing procedure of the ripe pseudo-ginseng of tradition is improved, has following advantage:
1)Shorten steaming time, reduce energy consumption, save management cost, be more suitable for mass producing.
2)Significantly improve the content of notoginseng polysaccharide and radix notoginseng flavones:The content of notoginseng polysaccharide in raw sangqi ginseng than increasing 1.5- 3 times, increase 80%-200% than commonly steaming in ripe pseudo-ginseng;The content of radix notoginseng flavones is than increasing 2-4 times in raw sangqi ginseng, than common Steaming in ripe pseudo-ginseng increases 100%-300%.
3)Strengthen in its theory of traditional Chinese medical science the effect of " entering Liver Channel " after vinegar system, have the function that liver protection, protect liver.
Embodiment
Following embodiments are the further explanations to the present invention, but are never limited the scope of the present invention.Referring to Embodiment is further elaborated on the present invention, it should be appreciated to those skilled in the art that the present invention is not limited to these implementations Example and the preparation method used.Moreover, description can be equal to the present invention those skilled in the art according to the present invention Replace, combine, improve or modify, but these are intended to be included in the scope of the present invention.
The fresh pseudo-ginseng vinegar system of embodiment 1 steams
Using fresh pseudo-ginseng as raw material, the dis-medicinal parts such as root are removed, after cleaning, are cut into fritter, powder after 50 DEG C of dryings It is broken into coarse powder.Coarse powder 100g is taken, takes 9 degree of rice vinegar 100g, when soaking at room temperature 12 is small, did not had pseudo-ginseng raw material to be advisable with 9 degree of rice vinegars, so Take out the pseudo-ginseng crossed by 9 degree of soaking in rice vinegar afterwards, normal pressure steam 12 it is small when, take out, put in heated-air circulation oven after steaming When drying 5 is small at 50 DEG C, dry into medicinal material, in 7%-13%, taking-up cools moisture, packs, to obtain the final product.
The dry pseudo-ginseng vinegar system of embodiment 2 steams
Using dry pseudo-ginseng as raw material, the coarse powder of 20 mesh sieves was ground into.Coarse powder 100g is taken, takes 9 degree of rice vinegar 50g, room temperature Soak 6 it is small when, do not had pseudo-ginseng raw material to be advisable with 9 degree of rice vinegars, and the pseudo-ginseng crossed by 9 degree of soaking in rice vinegar then taken out, in 110 DEG C Under, when high pressure steaming 2 is small, steam end taken out after pressure is down to normal pressure put in heated-air circulation oven at 70 DEG C it is dry 4 it is small when, Dry into medicinal material, in 7%-13%, taking-up cools moisture, packs, to obtain the final product.
3 fresh pseudo-ginseng of embodiment commonly steams
Using fresh pseudo-ginseng as raw material, the coarse powder of 20 mesh sieves was ground into.Take coarse powder 100g, normal pressure steam 12 it is small when, steam Taken out after system, put in heated-air circulation oven at 50 DEG C it is dry 5 it is small when, the dry moisture into medicinal material in 7%-13%, Taking-up cools, and packs, to obtain the final product.
4 dry pseudo-ginseng of embodiment commonly steams
Using dry pseudo-ginseng as raw material, the coarse powder of 20 mesh sieves was ground into.Take coarse powder 100g, normal pressure steam 12 it is small when, steam Taken out after system, put in heated-air circulation oven at 50 DEG C it is dry 5 it is small when, the dry moisture into medicinal material in 7%-13%, Taking-up cools, and packs, to obtain the final product.
5 control experiment of embodiment
Notoginseng polysaccharide and radix notoginseng flavones are one of its important active ingredient in pseudo-ginseng.There is radix notoginseng flavones increase to be preced with Shape artery blood flow, reduces myocardial oxygen consumption, improves the effect such as antioxidant capacity, anti-arrhythmia.Notoginseng polysaccharide, which has, to be promoted and adds Strong reticuloendothelial system function, promote antibody tormation, enhancing macrophage phagocytic activity, strengthen immunity, resisting microwave radiation, rush Acted on into wound and promotion bone defect healing etc. is recovered.
(1)Same raw sangqi ginseng, it is common steam pseudo-ginseng contrast, notoginseng polysaccharide in the ripe pseudo-ginseng of vinegar system prepared by the method for the present invention, The content of radix notoginseng flavones, which has, to be dramatically increased.
The ripe pseudo-ginseng of 1 vinegar system of table and raw sangqi ginseng, the notoginseng polysaccharide for commonly steaming ripe pseudo-ginseng, radix notoginseng flavones content balance table
Sample Notoginseng polysaccharide Radix notoginseng flavones
Raw sangqi ginseng(mg/g) 73 1.3
1 vinegar system of embodiment steams rear content(mg/g) 147 3.8
Embodiment 3 commonly steams rear content(mg/g) 94 2.1
2 vinegar system of embodiment steams rear content(mg/g) 136 4.0
Embodiment 4 commonly steams rear content(mg/g) 89 2.2
Embodiment 1 increases ratio (%) (compared with raw sangqi ginseng) 201 292
Embodiment 1 increases ratio (%) (compared with embodiment 3 commonly steams pseudo-ginseng) 156 181
As shown in Table 1, the content of notoginseng polysaccharide and radix notoginseng flavones is significantly larger than raw sangqi ginseng in the ripe pseudo-ginseng of vinegar system of the present invention Commonly steam the content of two kinds of components in pseudo-ginseng.
(2)Using embodiment 1(Fresh pseudo-ginseng vinegar system steams)Or embodiment 2(Dry pseudo-ginseng vinegar system steams)Technique, selected from not With the comparison of species and the rice vinegar of the number of degrees.
The ripe pseudo-ginseng of 2 vinegar system of table and raw sangqi ginseng, the notoginseng polysaccharide for commonly steaming ripe pseudo-ginseng, radix notoginseng flavones content balance table
Sample Notoginseng polysaccharide Radix notoginseng flavones
Raw sangqi ginseng(mg/g) 73 1.3
Embodiment 3 commonly steams rear content(mg/g) 94 2.1
Embodiment 4 commonly steams rear content(mg/g) 89 2.2
Comparative example 1(Fresh pseudo-ginseng, 5 degree of rice vinegar) 135 3.0
Comparative example 2(Dry pseudo-ginseng, 5 degree of rice vinegar) 128 2.9
Comparative example 3(Fresh pseudo-ginseng, 9 degree of light-coloured vinegar) 138 3.4
Comparative example 4(Dry pseudo-ginseng, 3 degree of rice vinegar) 116 2.7
Comparative example 5(Fresh pseudo-ginseng, 2 degree of mature vinegar) 119 2.5
Comparative example 6(Dry pseudo-ginseng, 8 degree of rice vinegar) 142 3.6
(3)Further, pseudo-ginseng is detected respectively at tri- time points of 2h, 8h, 12h for steaming of embodiment 1 and embodiment 3 The content of polysaccharide and radix notoginseng flavones, by table 3 as it can be seen that notoginseng polysaccharide and pseudo-ginseng are total in the processed product that preparation process of the present invention obtains The content of flavones is above common pseudo-ginseng processed product.
3 pseudo-ginseng vinegar system of table steams the notoginseng polysaccharide at rear 3 time points, the content detection of radix notoginseng flavones
(4)Further, using the preparation process of embodiment 1, when comparing using different vinegar products, the vinegar system of acquisition is detected The content of notoginseng polysaccharide and radix notoginseng flavones in pseudo-ginseng.It is as shown in the table, using the best results of rice vinegar.
Table 4 uses the ripe notoginseng polysaccharide of different vinegar systems and radix notoginseng flavones content balance table
Sample(It is 8 degree) Notoginseng polysaccharide (mg/g) Radix notoginseng flavones (mg/g)
Content after the mature vinegar system of Shanxi(mg/g) 77 1.4
Content after the light-coloured vinegar system of Hunan(mg/g) 84 1.8
Content after the light-coloured vinegar system of Shanghai(mg/g) 108 2.2
Content after extra large day dinner party aromatic vinegar system(mg/g) 87 1.5
Content after Beigushan Hill board zhenjiang vinegar system(mg/g) 99 2.7
Content after fixed speed wind turbine system(mg/g) 97 2.8
Content after rice vinegar system(mg/g) 147 3.8

Claims (9)

  1. A kind of 1. processing procedure of the ripe pseudo-ginseng of vinegar system, it is characterised in that:Include the following steps:
    A, using pseudo-ginseng as raw material, the 0.15-3 times of vinegar measured immersion is added in terms of pseudo-ginseng weight, soaking conditions are:5-30 DEG C, 1-24 Hour;
    B, the pseudo-ginseng after step A immersions is taken to be steamed with steam, the condition of steaming is:Pressure is 0.1-0.18MPa, temperature 100- 130 DEG C, when the time is 2-48 small;
    C, drying;
    Wherein, the vinegar described in step A is selected from rice vinegar, aromatic vinegar, mature vinegar, light-coloured vinegar or acetin.
  2. 2. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:The number of degrees of vinegar described in step A Selected from 1-9 degree.
  3. 3. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:Step C drying conditions:Dry temperature Degree is preferably 40-100 DEG C, when drying time is preferably 3-8 small.
  4. 4. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:Drying includes micro- described in step C Ripple drying, naturally dry, heated-air circulation oven drying or superconductive energy-saving drying.
  5. 5. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:In step A in terms of pseudo-ginseng weight Add the 0.15-1 times of vinegar measured immersion.
  6. 6. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:Soaking conditions are in step A:5- 30 DEG C, when 1-12 is small.
  7. 7. the processing procedure of the ripe pseudo-ginseng of vinegar system according to claim 1, it is characterised in that:Step B steams condition:Pressure For 0.1-0.18MPa, temperature is 100-130 DEG C, when the time is 2-24 small.
  8. 8. claim 1-7 any one of them processing procedure prepares the ripe pseudo-ginseng of vinegar system of gained.
  9. 9. application of the ripe pseudo-ginseng of vinegar system in liver protection and/or liver-protecting medicine is prepared according to obtained by claim 8.
CN201410035656.7A 2014-01-24 2014-01-24 A kind of ripe pseudo-ginseng of vinegar system and its processing procedure and application Active CN104800257B (en)

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CN107308196A (en) * 2017-07-11 2017-11-03 天马(安徽)国药科技股份有限公司 Method for processing pseudo-ginseng
CN108042592A (en) * 2018-02-09 2018-05-18 云南三七科技有限公司 A kind of preparation method of ripe notoginseng decoction piece
CN112891385B (en) * 2021-04-09 2022-05-20 建昌帮药业有限公司 Cooked pseudo-ginseng and preparation method thereof
CN113633667A (en) * 2021-09-26 2021-11-12 许昌学院 Traditional Chinese medicine processing method for reducing toxic and side effects of traditional Chinese medicine

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