CN104800257A - Vinegar processed pseudo-ginseng and processing technology and application thereof - Google Patents
Vinegar processed pseudo-ginseng and processing technology and application thereof Download PDFInfo
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- CN104800257A CN104800257A CN201410035656.7A CN201410035656A CN104800257A CN 104800257 A CN104800257 A CN 104800257A CN 201410035656 A CN201410035656 A CN 201410035656A CN 104800257 A CN104800257 A CN 104800257A
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- vinegar
- radix notoginseng
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Abstract
The present invention relates to a novel processing method of pseudo-ginseng and belongs to the field of medicine. The invention discloses a vinegar processed pseudo-ginseng and a processing technology and application thereof. The processing technology comprises the following steps: A, using pseudo-ginseng as a raw material, adding vinegarin the amount 0.15-3 times of the pseudo-ginseng and soaking; B, steaming the soaked pseudo-ginseng with steam; and C, drying. The method can substantially increase the contents of pseudo-ginseng polysaccharide and pseudo-ginseng general flavone.
Description
Technical field
The present invention relates to the new concocting method of a kind of Radix Notoginseng, especially the processing procedure of vinegar cooked Radix Notoginseng and application, belong to tcm field.
Background technology
Pseudo-ginseng is the dry root and rhizome of panax araliaceae plant, belong to rare Chinese medicine, be distributed in the ground such as Yunnan, Guangxi, tool dissipating blood stasis stops blooding, the effect of subduing swelling and relieving pain, tcm clinical practice is usually used in spitting of blood, haematemesis, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
The prepared slices of Chinese crude drugs be Chinese crude drug by the medicine for clinical treatment after Preparation process, tcm clinical practice application notoginseng decoction piece be divided into raw sangqi ginseng and cooked Radix Notoginseng two kinds of processed products.Raw sangqi ginseng is longer than blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain, and cure mainly wound, pain, blood disorder etc., cooked Radix Notoginseng is longer than and is nourished blood, QI invigorating, strengthening by means of tonics, cures mainly card such as deficiency of vital energy blood weak grade.
Traditional concocting method of cooked Radix Notoginseng, for steaming, is steaming in process, the main component (ginsenoside Rg in raw sangqi ginseng
1, Rb
1, Rd, Re and Panax Notoginseng saponin R
1) be progressively converted into new saponin constituent, be respectively ginsenoside 20 (S)-Rh
1, 20 (R)-Rh
1, Rk
3, Rh
4, 20 (S)-Rg
3, 20 (R)-Rg
3, Rk
1and Rg
5.
Cooked Radix Notoginseng common steams that the process time is long, temperature is high, energy consumption is large, management difficulty is large, is its weak point.Modern process of preparing Chinese medicine is learned in research, and steam technique to Radix Notoginseng and be studied specially, as Chinese patent application 200610010771.4, a kind of Radix Notoginseng processing method and products thereof provides one and steams Radix Notoginseng.
But the content being steamed two other important component Radix Notoginseng polysaccharide and total flavones in the Radix Notoginseng obtained with existing concocting method in prior art by tradition is lower, seriously compromises the medicinal efficacy of Radix Notoginseng.
Summary of the invention
The object of this invention is to provide the new processed product of a kind of Radix Notoginseng, i.e. vinegar cooked Radix Notoginseng.
The object of this invention is to provide vinegar cooked Radix Notoginseng preparation protect the liver and/or hepatoprotective medicine in application.
The object of this invention is to provide the new processing procedure of a kind of Radix Notoginseng, comprise the steps:
A, be raw material with Radix Notoginseng, the vinegar adding 0.15-3 times amount with Radix Notoginseng weighing scale soaks, and soaking conditions is: 5-30 DEG C, 1-24 hour;
B, get steps A soak after Radix Notoginseng steam with steam, the condition of steaming is: pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, and the time is 2-48 hour;
C, drying.
As one of preferred technical scheme, the Radix Notoginseng in step A can make pulverization process before vinegar soaks, because pseudo-ginseng is bull tuberous root, after beating powder, vinegar bubble more easily absorbs pickle, better plays the effect of vinegar.
As one of preferred technical scheme, steam dried Radix Notoginseng in step C and carry out pulverization process again, the granularity after pulverizing can be controlled in coarse granularity, e.g., crosses 10 order-40 mesh sieves.
Wherein, the vinegar described in steps A comprises rice vinegar, aromatic vinegar, mature vinegar, white vinegar, vinegar essence.Described rice vinegar is raw material with rice, leads to by traditional handicraft; Described aromatic vinegar is that primary raw material is brewageed with Oryza glutinosa; Described mature vinegar is that primary raw material aging forms with Sorghum vulgare Pers.; Described white vinegar is the common white vinegar of synthetic; Described vinegar essence is that the dilution of edible ice acetic acid forms.
The number of degrees that above-mentioned vinegar adopts comprise 1 – 9 degree.The number of degrees of vinegar are preferably 6 degree of tablet vinegar, 9 degree of rice vinegars, vinegar essence (2-3 degree).
Further, the vinegar immersion of 0.15-1 times amount is added in steps A with Radix Notoginseng weighing scale.
Further, in steps A, soaking conditions is: 5-30 DEG C, 1-12 hour.
Further, step B steams condition and is: pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, and the time is 2-24 hour.
When step C is dry, preferably controlling medical material moisture is 7%-13%.Preferred drying condition is as follows: baking temperature is 40-100 DEG C, and drying time is 3-8 hour.
This areas such as the present invention's drying mode used comprises microwave drying, naturally dries, heated-air circulation oven is dried or superconductive energy-saving is dry know various drying means.
As one of preferred technical scheme, natural cooling after the drying of vinegar cooked Radix Notoginseng, packs.
Prepare the vinegar cooked Radix Notoginseng of gained according to processing procedure of the present invention, wherein the content of Radix Notoginseng polysaccharide and radix notoginseng flavones significantly improves: the content of Radix Notoginseng polysaccharide, than increasing 1.5-3 in raw sangqi ginseng doubly, increases 80%-200% than common steaming in Radix Notoginseng.The content of radix notoginseng flavones, than increasing 2-4 in raw sangqi ginseng doubly, increases 100%-300% than common steaming in Radix Notoginseng.In addition, after vinegar system, strengthen the effect " entering Liver Channel " in its theory of Chinese medical science, reach protect the liver, the effect of hepatoprotective.
The method is easy, efficient, be easy to operation, and it is with low cost, compared with steaming cooked Radix Notoginseng concocting method with tradition, the steaming time reached needed for identical saponin content significantly reduces, and the content of Radix Notoginseng polysaccharide and radix notoginseng flavones can be significantly improved, energy savings, is applicable to being applied to large-scale production very much.Can be used widely at new drug development, health food innovation area simultaneously.
beneficial effect
The present invention adopts vinegar system+Powder Made by Steamed Method, improves the processing procedure of traditional cooked Radix Notoginseng, has following advantage:
1) shorten steaming time, reduce energy consumption, save management cost, be more suitable for large-scale production.
2) content of Radix Notoginseng polysaccharide and radix notoginseng flavones is significantly improved: the content of Radix Notoginseng polysaccharide, than increasing 1.5-3 in raw sangqi ginseng doubly, increases 80%-200% than common steaming in cooked Radix Notoginseng; The content of radix notoginseng flavones, than increasing 2-4 in raw sangqi ginseng doubly, increases 100%-300% than common steaming in cooked Radix Notoginseng.
3) strengthen the effect " entering Liver Channel " in its theory of Chinese medical science after vinegar system, reach protect the liver, the effect of hepatoprotective.
Detailed description of the invention
Following examples further illustrate of the present invention, but never limit the scope of the present invention.Elaborate the present invention further referring to embodiment, but it will be appreciated by those skilled in the art that the present invention is not limited to the preparation method of these embodiments and use.And those skilled in the art can carry out equivalent replacement, combination, improvement to the present invention according to description of the invention or modify, but these all will comprise within the scope of the invention.
the fresh Radix Notoginseng vinegar system of embodiment 1 steams
With fresh Radix Notoginseng for raw material, the dis-medicinal parts such as removing root hair, after cleaning, be cut into fritter, 50 DEG C of crushed after being dried become coarse powder.Get coarse powder 100g, get 9 degree of rice vinegar 100g, soaking at room temperature 12 hours, do not have Radix Notoginseng raw material to be advisable with 9 degree of rice vinegars, then the Radix Notoginseng crossed through 9 degree of soaking in rice vinegar is taken out, normal pressure steams 12 hours, steams after terminating and takes out, and to put in heated-air circulation oven at 50 DEG C dry 5 hours, to be dried in medical material moisture when 7%-13%, taking-up cools, and packs, and to obtain final product.
the dry Radix Notoginseng vinegar system of embodiment 2 steams
With dry Radix Notoginseng for raw material, be ground into the coarse powder of 20 mesh sieves.Get coarse powder 100g, get 9 degree of rice vinegar 50g, soaking at room temperature 6 hours, do not have Radix Notoginseng raw material to be advisable with 9 degree of rice vinegars, then the Radix Notoginseng crossed through 9 degree of soaking in rice vinegar is taken out, at 110 DEG C, high pressure steaming 2 hours, steams end and takes out after Pressure Drop to normal pressure and to put in heated-air circulation oven at 70 DEG C dry 4 hours, to be dried in medical material moisture when 7%-13%, taking-up cools, and packs, and to obtain final product.
the fresh Radix Notoginseng of embodiment 3 is common to be steamed
With fresh Radix Notoginseng for raw material, be ground into the coarse powder of 20 mesh sieves.Get coarse powder 100g, normal pressure steams 12 hours, steams after terminating and takes out, and to put in heated-air circulation oven at 50 DEG C dry 5 hours, is dried in medical material that moisture is when 7%-13%, and taking-up cools, and packs, and to obtain final product.
the dry Radix Notoginseng of embodiment 4 is common to be steamed
With dry Radix Notoginseng for raw material, be ground into the coarse powder of 20 mesh sieves.Get coarse powder 100g, normal pressure steams 12 hours, steams after terminating and takes out, and to put in heated-air circulation oven at 50 DEG C dry 5 hours, is dried in medical material that moisture is when 7%-13%, and taking-up cools, and packs, and to obtain final product.
embodiment 5 control experiment
In Radix Notoginseng, Radix Notoginseng polysaccharide and radix notoginseng flavones are one of its important active component.Radix notoginseng flavones has increase coronary flow, reduces myocardial oxygen consumption, improves antioxidant capacity, the effects such as arrhythmia.Radix Notoginseng polysaccharide has promotion and generates with reinforcement reticuloendothelial system function, enhancing antibody, strengthens the effects such as macrophage phagocytic activity, enhancing immunity, resisting microwave radiation, promotion recovery wound and promotion bone defect healing.
(1) same to raw sangqi ginseng, common steam Radix Notoginseng contrast, the Radix Notoginseng polysaccharide in vinegar cooked Radix Notoginseng prepared by the inventive method, the content of radix notoginseng flavones have remarkable increase.
Table 1 vinegar cooked Radix Notoginseng and raw sangqi ginseng, common Radix Notoginseng polysaccharide, the radix notoginseng flavones content balance table steaming cooked Radix Notoginseng
| Sample | Radix Notoginseng polysaccharide | Radix notoginseng flavones |
| Raw sangqi ginseng (mg/g) | 73 | 1.3 |
| Embodiment 1 vinegar system steams rear content (mg/g) | 147 | 3.8 |
| Embodiment 3 is common steams rear content (mg/g) | 94 | 2.1 |
| Embodiment 2 vinegar system steams rear content (mg/g) | 136 | 4.0 |
| Embodiment 4 is common steams rear content (mg/g) | 89 | 2.2 |
| Embodiment 1 increases ratio (%) (compared with raw sangqi ginseng) | 201 | 292 |
| Embodiment 1 increases ratio (%) (steaming compared with Radix Notoginseng with embodiment 3 is common) | 156 | 181 |
As shown in Table 1, in vinegar cooked Radix Notoginseng of the present invention the content of Radix Notoginseng polysaccharide and radix notoginseng flavones far away higher than raw sangqi ginseng and the common content steaming two kinds of compositions in Radix Notoginseng.
(2) adopt embodiment 1(fresh Radix Notoginseng vinegar system to steam) or embodiment 2(dry Radix Notoginseng vinegar system steam) technique, be selected from the comparison of the rice vinegar of variety classes and the number of degrees.
Table 2 vinegar cooked Radix Notoginseng and raw sangqi ginseng, common Radix Notoginseng polysaccharide, the radix notoginseng flavones content balance table steaming cooked Radix Notoginseng
| Sample | Radix Notoginseng polysaccharide | Radix notoginseng flavones |
| Raw sangqi ginseng (mg/g) | 73 | 1.3 |
| Embodiment 3 is common steams rear content (mg/g) | 94 | 2.1 |
| Embodiment 4 is common steams rear content (mg/g) | 89 | 2.2 |
| The fresh Radix Notoginseng of comparative example 1(, rice vinegar 5 degree) | 135 | 3.0 |
| The dry Radix Notoginseng of comparative example 2(, rice vinegar 5 degree) | 128 | 2.9 |
| The fresh Radix Notoginseng of comparative example 3(, white vinegar 9 degree) | 138 | 3.4 |
| The dry Radix Notoginseng of comparative example 4(, rice vinegar 3 degree) | 116 | 2.7 |
| The fresh Radix Notoginseng of comparative example 5(, 2 degree, mature vinegar) | 119 | 2.5 |
| The dry Radix Notoginseng of comparative example 6(, rice vinegar 8 degree) | 142 | 3.6 |
(3) further, the content of Radix Notoginseng polysaccharide and radix notoginseng flavones is detected respectively at 2h, 8h, 12h of steaming tri-time points of embodiment 1 and embodiment 3, from table 3, in the processed product that preparation technology of the present invention obtains, the content of Radix Notoginseng polysaccharide and radix notoginseng flavones is all higher than common Radix Notoginseng processed product.
Table 3 Radix Notoginseng vinegar system steams the rear Radix Notoginseng polysaccharide of 3 time points, the content detection of radix notoginseng flavones
(4) further, the preparation technology of embodiment 1 is adopted, when comparing the different vinegar goods of employing, the Radix Notoginseng polysaccharide in the vinegar Radix Notoginseng that detection obtains and the content of radix notoginseng flavones.As shown in the table, adopt the best results of rice vinegar.
Table 4 uses different vinegar cooked Radix Notoginseng polysaccharide and radix notoginseng flavones content balance table
| Sample (being 8 degree) | Radix Notoginseng polysaccharide (mg/g) | Radix notoginseng flavones (mg/g) |
| Content (mg/g) after the mature vinegar system of Shanxi | 77 | 1.4 |
| Content (mg/g) after the white vinegar system of Hunan | 84 | 1.8 |
| Content (mg/g) after the white vinegar system of Shanghai | 108 | 2.2 |
| Content (mg/g) after sea sky dinner party aromatic vinegar system | 87 | 1.5 |
| Content (mg/g) after Beigushan Hill board zhenjiang vinegar system | 99 | 2.7 |
| Content (mg/g) after fixed speed wind turbine system | 97 | 2.8 |
| Content (mg/g) after rice vinegar system | 147 | 3.8 |
Claims (10)
1. a processing procedure for vinegar cooked Radix Notoginseng, is characterized in that: comprise the steps:
A, be raw material with Radix Notoginseng, the vinegar adding 0.15-3 times amount with Radix Notoginseng weighing scale soaks, and soaking conditions is: 5-30 DEG C, 1-24 hour;
B, get steps A soak after Radix Notoginseng steam with steam, the condition of steaming is: pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, and the time is 2-48 hour;
C, drying.
2. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: the vinegar described in steps A is selected from rice vinegar, aromatic vinegar, mature vinegar, white vinegar or vinegar essence.
3. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: the number of degrees of the vinegar described in steps A are selected from 1-9 degree.
4. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: step C drying condition: baking temperature is preferably 40-100 DEG C, drying time is preferably 3-8 hour.
5. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: drying described in step C comprises microwave drying, naturally dries, heated-air circulation oven is dried or superconductive energy-saving is dry.
6. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: the vinegar immersion adding 0.15-1 times amount in steps A with Radix Notoginseng weighing scale.
7. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: in steps A, soaking conditions is: 5-30 DEG C, 1-12 hour.
8. the processing procedure of vinegar cooked Radix Notoginseng according to claim 1, is characterized in that: step B steams condition and is: pressure is 0.1-0.18MPa, and temperature is 100-130 DEG C, and the time is 2-24 hour.
9. the processing procedure described in any one of claim 1-8 prepares the vinegar cooked Radix Notoginseng of gained.
10. according to the vinegar cooked Radix Notoginseng of claim 9 gained preparation protect the liver and/or hepatoprotective medicine in application.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107308196A (en) * | 2017-07-11 | 2017-11-03 | 天马（安徽）国药科技股份有限公司 | A kind of concocting method of pseudo-ginseng |
| CN108042592A (en) * | 2018-02-09 | 2018-05-18 | 云南三七科技有限公司 | A kind of preparation method of ripe notoginseng decoction piece |
| CN112891385A (en) * | 2021-04-09 | 2021-06-04 | 建昌帮药业有限公司 | Cooked pseudo-ginseng and preparation method thereof |
| CN113633667A (en) * | 2021-09-26 | 2021-11-12 | 许昌学院 | Traditional Chinese medicine processing method for reducing toxic and side effects of traditional Chinese medicine |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308196A (en) * | 2017-07-11 | 2017-11-03 | 天马（安徽）国药科技股份有限公司 | A kind of concocting method of pseudo-ginseng |
| CN108042592A (en) * | 2018-02-09 | 2018-05-18 | 云南三七科技有限公司 | A kind of preparation method of ripe notoginseng decoction piece |
| CN112891385A (en) * | 2021-04-09 | 2021-06-04 | 建昌帮药业有限公司 | Cooked pseudo-ginseng and preparation method thereof |
| CN112891385B (en) * | 2021-04-09 | 2022-05-20 | 建昌帮药业有限公司 | Cooked pseudo-ginseng and preparation method thereof |
| CN113633667A (en) * | 2021-09-26 | 2021-11-12 | 许昌学院 | Traditional Chinese medicine processing method for reducing toxic and side effects of traditional Chinese medicine |
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