CN103349751B - Mongolian medicine composition for treating diabetic nephropathy and preparation method thereof - Google Patents
Mongolian medicine composition for treating diabetic nephropathy and preparation method thereof Download PDFInfo
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- CN103349751B CN103349751B CN201310253817.5A CN201310253817A CN103349751B CN 103349751 B CN103349751 B CN 103349751B CN 201310253817 A CN201310253817 A CN 201310253817A CN 103349751 B CN103349751 B CN 103349751B
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Abstract
The invention discloses a mongolian medicine composition for treating diabetic nephropathy. The mongolian medicine composition is prepared from the following materials in parts by weight: 15-25 parts of gypsum, 15-25 parts of flowers carthami, 15-25 parts of clove, 15-25 parts of myristica fragrans, 15-25 parts of amomum cardamomum, 15-25 parts of amomum tsao-ko, 15-25 parts of rhizoma polygonati, 15-25 parts of radix polygonati officinalis, 15-25 parts of bletilla striata, 15-25 parts of radix asparagi, 15-25 parts of fructus choerospondiatis, 90-150 parts of ginseng, and 82.5-138 parts of polygonum bistorta. Meanwhile, the invention also discloses a corresponding preparation method. The product disclosed by the invention has good effects of improving symptoms and protecting the kidney. The preparation method is simple and easy to popularize.
Description
Technical field
The invention belongs to the field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of diabetic nephropathy and preparation method thereof.
Background technology
Diabetic nephropathy is commonly encountered diseases, the frequently-occurring disease of serious threat human health.Nearly 9,000 ten thousand diabeticss of current China, wherein 1/3 suffers from DN.DN accounts for the 30%-50% of the chronic renal failure cause of disease, is most important paathogenic factor in single disease.DN is the primary paathogenic factor of whole world end stagerenaldisease, and relevant with the increase of cardiovascular disease risk.DN has a strong impact on work capacity and the quality of life of patient, takies a large amount of medical resource, brings heavy financial burden to society and family.The pathogenesis of research DN and prophylactico-therapeutic measures have become the focus in endocrine metabolism field and nephropathy field.At present, Modern medical therapy primary disease is many sets about from aspects such as control blood glucose, blood pressure, adjustment lipid metabolism, low protein diet, the application of RAS blocker, and other are without special therapeutic method.In recent years, a large amount of clinical practice shows, Treated by Mongolian Medicine DN, and means are various, and pharmaceutical dosage form enriches simultaneously, has and improves symptom and Renoprotective Effect preferably.Therefore, give full play to Mongolia Medicine in the characteristic of preventing and treating in diabetic nephropathy and advantage, carry out and study the scheme of control DN in a deep going way, constantly screening delays the optimizing therapeutic regimen of DN renal failure, not only have broad prospects, also there is important clinical meaning simultaneously.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of Chinese medicine composition for the treatment of diabetic nephropathy and preparation method thereof.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine composition for the treatment of diabetic nephropathy, be prepared from by the raw material of following weight portion: Gypsum Fibrosum 15-25 part, Flos Carthami 15-25 part, Flos Caryophylli 15-25 part, Semen Myristicae 15-25 part, Fructus Amomi Rotundus 15-25 part, Fructus Tsaoko 15-25 part, Rhizoma Polygonati 15-25 part, Rhizoma Polygonati Odorati 15-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25 part, Radix Asparagi 15-25 part, Fructus Choerospondiatis 15-25 part, Radix Ginseng 90-150 part, palm ginseng 82.5-138 part.
Preferably, be prepared from through extracting by the Chinese medicine of following weight portion: Gypsum Fibrosum 18-23 part, Flos Carthami 18-23 part, Flos Caryophylli 18-23 part, Semen Myristicae 18-23 part, Fructus Amomi Rotundus 18-23 part, Fructus Tsaoko 18-23 part, Rhizoma Polygonati 18-23 part, Rhizoma Polygonati Odorati 18-23 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 18-23 part, Radix Asparagi 18-23 part, Fructus Choerospondiatis 18-23 part, Radix Ginseng 100-120 part, palm ginseng 100-135 part.
What more have choosing is, be prepared from through extracting by the Chinese medicine of following weight portion: 20 parts, Gypsum Fibrosum, 20 parts, Flos Carthami, Flos Caryophylli 20 parts, Semen Myristicae 20 parts, Fructus Amomi Rotundus 20 parts, Fructus Tsaoko 20 parts, Rhizoma Polygonati 20 parts, Rhizoma Polygonati Odorati 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Radix Asparagi 20 parts, Fructus Choerospondiatis 20 parts, Radix Ginseng 120 parts, palm ginseng 110 parts.
Present invention also offers a kind of method preparing above-mentioned Chinese medicine composition, specifically comprise the following steps:
(1) Gypsum Fibrosum: get Gypsum Fibrosum and clean, removing impurity, puts in ironware and forges, and takes out, cools;
(2) Rhizoma Polygonati: get dry rhizome, removes impurity, cleans, and section or section are dry, get clean medical material and put into fresh milk and add appropriate water, wherein every 10kg medical material 5L milk, when warm fire boils the thoroughly heart whole in milk, takes out, dries;
(3) Radix Asparagi: the dried root getting Radix Asparagi, removing impurity, section or section, dry, get clean medical material and put into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(4) Rhizoma Polygonati Odorati: get polygonati rhizoma and shine to soft, gently rub 1 time, then shine, rub again, repeatedly several times until soft without hard-core time, shine to absolutely dry, removing impurity, cleans, section or section, dry, get clean medical material to put into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(5) palm ginseng: get palm ginseng dry rhizome, removing impurity, cleans, and section or section are dry, gets clean medical material and puts into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(6) Fructus Amomi Rotundus, Fructus Tsaoko: get Fructus Tsaoko mature fruit, removing impurity, cleans, and dries;
(7) Semen Myristicae: get Semen Myristicae mature fruit, cut peel open, peel off aril, then strike shelling shape and obtain seed coat, take out kernel lime cream soak 1 day afterwards slow fire dry;
(8) Radix Ginseng: the dry root getting Radix Ginseng, removing impurity, cleans, dries after steaming;
(9) Pseudobulbus Bletillae (Rhizoma Bletillae): the dried root getting Radix Asparagi, removing impurity, cleans to put in boiling water and boils to during without the white heart, takes out and shines to half-dried, hit and get crust, dry;
(10) Flos Carthami: pluck when Flos Carthami is red by xanthochromia, dry in the shade;
(11) Flos Caryophylli: pluck alabastrum when Flos Caryophylli alabastrum has green to turn red, dry in the shade;
(12) Fructus Choerospondiatis: get Fructus Choerospondiatis mature fruit, removing impurity, cleans, dries in the shade;
(13) by the above-mentioned raw material handled well pill with water furnishing 200mg after the mixing that grinds to the powder altogether.
Have employed technique scheme, by the pharmacology analysis to Chinese medicine of the present invention, it has following function: slake thirst and help produce saliva, kidney-replenishing, only seminal emission, detumescence.And effectively can treat the disease such as soreness of the waist and knees, frequent micturition turbid urine, xerostomia happiness drink, lassitude that diabetic nephropathy causes.
A large amount of clinical practice shows, product of the present invention and preparation method have improves symptom and Renoprotective Effect preferably.Meanwhile, by Chinese medicine clinical treatment more than 100 example of the present invention, through continuous several course of therapy, satisfied effect is all reached.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described.
Embodiment 1
Raw material is according to following weight proportion: 20 parts, Gypsum Fibrosum, 20 parts, Flos Carthami, Flos Caryophylli 20 parts, Semen Myristicae 20 parts, Fructus Amomi Rotundus 20 parts, Fructus Tsaoko 20 parts, Rhizoma Polygonati 20 parts, Rhizoma Polygonati Odorati 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Radix Asparagi 20 parts, Fructus Choerospondiatis 20 parts, Radix Ginseng 120 parts, palm ginseng 110 parts, its preparation method specifically comprises the following steps:
(1) Gypsum Fibrosum: get Gypsum Fibrosum and clean, removing impurity, puts in ironware and forges, and takes out, cools;
(2) Rhizoma Polygonati: get dry rhizome, removes impurity, cleans, and section or section are dry, get clean medical material and put into fresh milk and add appropriate water, wherein every 10kg medical material 5L milk, when warm fire boils the thoroughly heart whole in milk, takes out, dries;
(3) Radix Asparagi: the dried root getting Radix Asparagi, removing impurity, section or section, dry, get clean medical material and put into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(4) Rhizoma Polygonati Odorati: get polygonati rhizoma and shine to soft, gently rub 1 time, then shine, rub again, repeatedly several times until soft without hard-core time, shine to absolutely dry, removing impurity, cleans, section or section, dry, get clean medical material to put into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(5) palm ginseng: get palm ginseng dry rhizome, except roguing is former, clean, section or section, dry, get clean medical material and put into fresh milk and add suitable quantity of water, wherein every 10kg medical material 5L milk, warm fire boil to milk all thoroughly the heart time, take out, dry;
(6) Fructus Amomi Rotundus, Fructus Tsaoko: get Fructus Tsaoko mature fruit, removing impurity, cleans, and dries;
(7) Semen Myristicae: get Semen Myristicae mature fruit, cut peel open, peel off aril, then strike shelling shape and obtain seed coat, take out kernel lime cream soak 1 day afterwards slow fire dry;
(8) Radix Ginseng: the dry root getting Radix Ginseng, removing impurity, cleans, dries after steaming;
(9) Pseudobulbus Bletillae (Rhizoma Bletillae): the dried root getting Radix Asparagi, removing impurity, cleans to put in boiling water and boils to during without the white heart, takes out and shines to half-dried, hit and get crust, dry;
(10) Flos Carthami: pluck when Flos Carthami is red by xanthochromia, dry in the shade;
(11) Flos Caryophylli: pluck alabastrum when Flos Caryophylli alabastrum has green to turn red, dry in the shade;
(12) Fructus Choerospondiatis: get Fructus Choerospondiatis mature fruit, removing impurity, cleans, dries in the shade;
(13) by the above-mentioned raw material handled well pill with water furnishing 200mg after the mixing that grinds to the powder altogether.
Embodiment 2
Raw material is according to following weight proportion: 19 parts, Gypsum Fibrosum, 19 parts, Flos Carthami, Flos Caryophylli 19 parts, Semen Myristicae 19 parts, Fructus Amomi Rotundus 19 parts, Fructus Tsaoko 19 parts, Rhizoma Polygonati 19 parts, Rhizoma Polygonati Odorati 19 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 19 parts, Radix Asparagi 19 parts, Fructus Choerospondiatis 19 parts, Radix Ginseng 110 parts, palm ginseng 120 parts, its preparation method is identical with embodiment 1.
Embodiment 3
Raw material is according to following weight proportion: 23 parts, Gypsum Fibrosum, 23 parts, Flos Carthami, Flos Caryophylli 23 parts, Semen Myristicae 23 parts, Fructus Amomi Rotundus 23 parts, Fructus Tsaoko 23 parts, Rhizoma Polygonati 23 parts, Rhizoma Polygonati Odorati 23 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 23 parts, Radix Asparagi 23 parts, Fructus Choerospondiatis 23 parts, Radix Ginseng 140 parts, palm ginseng 130 parts, its preparation method is identical with embodiment 1.
The present invention is not limited to above-mentioned concrete embodiment, and those of ordinary skill in the art, from above-mentioned design, without all conversion done by performing creative labour, all drops within protection scope of the present invention.
Claims (3)
1. treat the Chinese medicine composition of diabetic nephropathy for one kind, it is characterized in that: be prepared from by the raw material of following weight portion: Gypsum Fibrosum 15-25 part, Flos Carthami 15-25 part, Flos Caryophylli 15-25 part, Semen Myristicae 15-25 part, Fructus Amomi Rotundus 15-25 part, Fructus Tsaoko 15-25 part, Rhizoma Polygonati 15-25 part, Rhizoma Polygonati Odorati 15-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25 part, Radix Asparagi 15-25 part, Fructus Choerospondiatis 15-25 part, Radix Ginseng 90-150 part, palm ginseng 82.5-138 part.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that: be prepared from through extracting by the Chinese medicine of following weight portion: Gypsum Fibrosum 18-23 part, Flos Carthami 18-23 part, Flos Caryophylli 18-23 part, Semen Myristicae 18-23 part, Fructus Amomi Rotundus 18-23 part, Fructus Tsaoko 18-23 part, Rhizoma Polygonati 18-23 part, Rhizoma Polygonati Odorati 18-23 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 18-23 part, Radix Asparagi 18-23 part, Fructus Choerospondiatis 18-23 part, Radix Ginseng 100-120 part, palm ginseng 100-135 part.
3. Chinese medicine composition as claimed in claim 1 or 2, it is characterized in that: be prepared from through extracting by the Chinese medicine of following weight portion: 20 parts, Gypsum Fibrosum, 20 parts, Flos Carthami, Flos Caryophylli 20 parts, Semen Myristicae 20 parts, Fructus Amomi Rotundus 20 parts, Fructus Tsaoko 20 parts, Rhizoma Polygonati 20 parts, Rhizoma Polygonati Odorati 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Radix Asparagi 20 parts, Fructus Choerospondiatis 20 parts, Radix Ginseng 120 parts, palm ginseng 110 parts.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1582985A (en) * | 2004-03-08 | 2005-02-23 | 吕小苗 | Medicine for diabetes and its preparation |
| CN102846946A (en) * | 2011-06-28 | 2013-01-02 | 河北以岭医药研究院有限公司 | Application of Chinese medicine composition in preparation of diabetic nephropathy treatment drug |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1582985A (en) * | 2004-03-08 | 2005-02-23 | 吕小苗 | Medicine for diabetes and its preparation |
| CN102846946A (en) * | 2011-06-28 | 2013-01-02 | 河北以岭医药研究院有限公司 | Application of Chinese medicine composition in preparation of diabetic nephropathy treatment drug |
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Granted publication date: 20150107 Termination date: 20160610 |