CN103800875A - Traditional Chinese medicine for treating chronic renal failure and preparation method thereof - Google Patents

Traditional Chinese medicine for treating chronic renal failure and preparation method thereof Download PDF

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Publication number
CN103800875A
CN103800875A CN201410019794.6A CN201410019794A CN103800875A CN 103800875 A CN103800875 A CN 103800875A CN 201410019794 A CN201410019794 A CN 201410019794A CN 103800875 A CN103800875 A CN 103800875A
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grams
herba
chinese medicine
renal failure
chronic renal
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于宗慧
李显红
任永环
仇世钦
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Qingdao Chengyang Peoples Hospital
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Qingdao Chengyang Peoples Hospital
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Abstract

The invention discloses a traditional Chinese medicine for treating chronic renal failure. The traditional Chinese medicine is characterized by being prepared from the following medicinal materials by weight: 14-15g of tuckahoe, 9-10g of atractylodes macrocephala, 5-6g of costus root, 9-10g of cassia twig, 9-10g of agriophyllum squarrosum, 9-10g of dried ginger, 9-10g of magnolia bark, 14-15g of motherwort, 14-15g of asiatic bilberry, 14-15g of plantain, 0-20g of eulaliopsis binata and 0-15g of corn stigma. A preparation method of the traditional Chinese medicine comprises the steps of weighing the medicinal materials, placing the medicinal materials in a vessel, adding water, of which the weight is 8 times that of the medicinal materials, decocting for 1.5 hours, and filtrating, so as to obtain a filtrate and filtrated residue; adding water, of which the weight is 6 times that of the filtrated residue, into the filtrated residue, decocting for 1 hour, and filtrating, so as to obtain a filtrate and filtrated residue; combining the filtrates, concentrating, drying and filling into capsule shells. Proved by clinical trials, through selecting appropriate medicinal materials and proportioning ratio thereof, the traditional Chinese medicine achieves a remarkable effect on the treatment of chronic renal failure, is safe and is free from toxic and side effects.

Description

A kind of Chinese medicine that is used for the treatment of chronic renal failure and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of chronic renal failure and preparation method thereof.
Background technology
Chronic renal failure is a syndrome, is because various chronic renal disease renal hypofunction in late period causes.Clinical manifestation is water, electrolyte and acid base imbalance, and because toxin stores the serial poisoning symptom causing, prognosis is poor.In renal hypofunction, body has produced adaptability, but this adaptability is limited, in the time that impaired renal function exceedes 50%, can occur the variation of a series of poisoning symptom of whole body and biochemical indicator.According to statistics, primary disease annual morbidity accounts for 0.5/10000th left and right of general population.The traditional Chinese medical science thinks, renal failure is to develop into spleen kidney yang by the different pathogeny of various diseases to decline, and not removing dampness of sun, makes turbid-water being generated inside, and turbid pathogen is jammed three warmers and produces.Therefore, the loss of spleen sun, decline of kidney-YANG is basis of renal failure, and turbid pathogen is jammed, and three warmers are not all right, and causing the internal organs such as cardiopulmonary, taste, liver impaired is its mark, diseased region is at kidney.Treatment for chronic renal failure still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of chronic renal failure and preparation method thereof, by selecting suitable medical material and proportioning thereof, reach to contribute to the remarkable efficacy of patients of chronic renal failure rehabilitation, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine that is used for the treatment of chronic renal failure, medical material by following weight proportion is prepared from: 14~15 grams, Poria, 9~10 grams of the Rhizoma Atractylodis Macrocephalaes, 5~6 grams of Radix Aucklandiae (Radix Vladimiriae), 9~10 grams of 9~10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 9~10 grams of Rhizoma Zingiberiss, 9~10 grams of Cortex Magnoliae Officinalis, 14~15 grams of Herba Leonuris, 14~15 grams of Fructus Vaccinii Bracteati, 14~15 grams of Herba Plantaginiss, 0~20 gram of Herba Poae Sphondylodis, 0~15 gram of Stigma Maydis.
As preferably, be prepared from by the medical material of following weight proportion: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss.
As preferably, be prepared from by the medical material of following weight proportion: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 15 grams of Stigma Maydis.
As preferably, be prepared from by the medical material of following weight proportion: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss.
As preferably, medical material by following weight proportion is prepared from: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss, 15 grams of Stigma Maydis.
A kind of preparation method of the Chinese medicine that is used for the treatment of chronic renal failure, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
As preferably, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, adds 8 times of water gagings, decocts 1.5 hours, filters; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
As preferably, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, adds 8 times of water gagings, decocts 1.5 hours, filters; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
The pharmacology analysis of the each Chinese medicinal ingredients of the present invention is as follows:
Poria [nature and flavor] is sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
The Rhizoma Atractylodis Macrocephalae [nature and flavor] is bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, frequent fetal movement.
Radix Aucklandiae (Radix Vladimiriae) [nature and flavor] is pungent, bitter, temperature.[return through] returns spleen, stomach, large intestine, three warmers, gallbladder meridian.[function cures mainly] promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used for having loose bowels.
Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Semen Agriophylli Squarrosi [source] is the husky fluffy seed of chenopod.Lay seed after fruit maturation autumn, removes impurity, dries.[function cures mainly] strengthening the spleen to promote digestion; Deliver antipyretic; Diuretic.Main eating accumulation; Dysphagia and regurgitation; Cat fever; Nephritis.
The dry rhizome that Rhizoma Zingiberis [source] this product is zingiber.[nature and flavor] are pungent, hot.[return through] returns spleen, stomach, kidney, the heart, lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, and phlegm retention is breathed with cough.
Dry dried bark, root bark and the branch skin of Cortex Magnoliae Officinalis [source] Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils..The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.
Fresh or the dry aerial parts of Herba Leonuri [source] labiate Herba Leonuri.[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.
Fructus Vaccinii Bracteati [source] Ericaceae Fructus Vaccinii Bracteati platymiscium Fructus Vaccinii Bracteati, is used as medicine with dry fruit.[function cures mainly] bone and muscle strengthening, kidney tonifying gas.For physical weakness, insufficiency of the spleen chronic diarrhea, emission, leucorrhea with red and white discharge.
The dry herb of Herba Plantaginis [source] Plantaginaceae plant Herba Plantaginis.[nature and flavor] are sweet, cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Herba Poae Sphondylodis [source] is the herb of rush family plant plan Medulla Junci.[nature and flavor] are sweet light, flat.[function cures mainly] heat-clearing and toxic substances removing, diuresis, pain relieving.Control urine leaching puckery, impetigo.
Style and the fresh idea of Stigma Maydis [source] grass family Zea plant Semen Maydis.[nature and flavor] are sweet, light, flat.[return through] returns bladder, liver, gallbladder meridian.[function cures mainly] inducing diuresis to remove edema, suppressing the hyperactive liver function of gallbladder promoting.For acute and chronic nephritis, edema, acute hepatitis, chronic hepatitis, hypertension, diabetes, chronic sinusitis, lithangiuria, Biliary Calculi, the diseases such as dysuria, damp and hot jaundice.And can prevent habitual abortion.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
Through clinical patients of chronic renal failure 341 examples of accepting for medical treatment, take the oral agents of making according to embodiment 1, two doses of every days, use continuously 21-60 days.Therapeutic evaluation: cure: transference cure; Effective: symptom alleviates, but do not disappear completely; Invalid: symptom does not disappear, without obviously changing.
Therapeutic outcome: cure and effective totally 289 examples, effective percentage, up to 84.7%, is followed up a case by regular visits to after June again, all without recurrence.
The specific embodiment
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss, 15 grams of Stigma Maydis, insert in container, adds 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of chronic renal failure.Oral, two doses of every days.
Embodiment 2
Take: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss, 15 grams of Stigma Maydis, insert in container, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Filtering residue adds 2 times of water gagings, decocts 1 hour, filters; Merge three times filtrate, concentrated.
Be used for the treatment of chronic renal failure.Oral, two doses of every days.
Embodiment 3
Take: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss, 15 grams of Stigma Maydis, insert in container, adds 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of chronic renal failure.Oral, two doses of every days.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Everyly belong to apparent variation or the still row in protection scope of the present invention of variation that technical scheme of the present invention extends out.

Claims (8)

1. one kind is used for the treatment of the Chinese medicine of chronic renal failure, it is characterized in that, medical material by following weight proportion is prepared from: 14~15 grams, Poria, 9~10 grams of the Rhizoma Atractylodis Macrocephalaes, 5~6 grams of Radix Aucklandiae (Radix Vladimiriae), 9~10 grams of 9~10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 9~10 grams of Rhizoma Zingiberiss, 9~10 grams of Cortex Magnoliae Officinalis, 14~15 grams of Herba Leonuris, 14~15 grams of Fructus Vaccinii Bracteati, 14~15 grams of Herba Plantaginiss, 0~20 gram of Herba Poae Sphondylodis, 0~15 gram of Stigma Maydis.
2. a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 1, it is characterized in that, medical material by following weight proportion is prepared from: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss.
3. a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 1, it is characterized in that, medical material by following weight proportion is prepared from: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 15 grams of Stigma Maydis.
4. a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 1, it is characterized in that, medical material by following weight proportion is prepared from: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss.
5. a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 1, it is characterized in that, medical material by following weight proportion is prepared from: 15 grams, Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 6 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of 10 grams of, Semen Agriophylli Squarrosis of Ramulus Cinnamomi, 10 grams of Rhizoma Zingiberiss, 10 grams of Cortex Magnoliae Officinalis, 15 grams of Herba Leonuris, 15 grams of Fructus Vaccinii Bracteati, 15 grams of Herba Plantaginiss, 20 grams of Herba Poae Sphondylodiss, 15 grams of Stigma Maydis.
6. one kind is used for the treatment of the preparation method of the Chinese medicine of chronic renal failure, it is characterized in that, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
7. the preparation method of a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 6, it is characterized in that, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
8. the preparation method of a kind of Chinese medicine that is used for the treatment of chronic renal failure according to claim 6, it is characterized in that, comprise the steps: to take Poria, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae (Radix Vladimiriae), Ramulus Cinnamomi, Semen Agriophylli Squarrosi, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Herba Leonuri, Fructus Vaccinii Bracteati, Herba Plantaginis, Herba Poae Sphondylodis, Stigma Maydis, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
CN201410019794.6A 2014-01-16 2014-01-16 Traditional Chinese medicine for treating chronic renal failure and preparation method thereof Pending CN103800875A (en)

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Publication number Priority date Publication date Assignee Title
CN104522800A (en) * 2014-12-18 2015-04-22 安徽唐人药业有限公司 Composite infusion for strengthening body and tonifying kidney

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