CN104784555A - Traditional Chinese medicine agent for treating rectal cancer - Google Patents

Abstract

The invention discloses a traditional Chinese medicine agent for treating rectal cancer. The traditional Chinese medicine agent is prepared from the following main raw materials in parts by weight: 12-16 parts of honeysuckle, 9-13 parts of perilla frutescens, 11-15 parts of nakedflower beautyberry branchlet and leaf, 6-9 parts of garden burnet, 10-17 parts of euscaphis root, 8-16 parts of elecampane, 11-16 parts of lagenaria sicerariae seeds, 12-18 parts of coptis chinensis, 10-16 parts of lalang grass rhizome, 13-19 parts of fiveleaf akebia fruit, 8-15 parts of panacis majoris rhizome, 9-14 parts of houttuynia cordata and 11-16 parts of Raphanus sativus L. The traditional Chinese medicine agent follows the principle of syndrome differentiation treatment of the traditional Chinese medicine, several natural traditional Chinese medicinal materials are integrated, and the traditional Chinese medicine agent has the effects of removing stasis, reducing swelling, regulating qi, removing stasis and clearing away heat and toxic materials and is exact in curative effect.

Description

A kind of Chinese medicine for the treatment of rectal cancer

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine for the treatment of rectal cancer.

Background technology

Cancer between rectal cancer refers to from pectinate line to proctosigmoid intersection is one of modal malignant tumor of digestive tract.Because pelvic cavity is goed deep in its position, anatomy relationship is complicated, and operation is not easily thorough, and Postoperative recurrent rate is high.Middle and lower rectal carcinoma and anal sphincter close, be difficult to the difficult problem that anus preserving and function thereof are operations during operation.China's rectal cancer age of onset median is at one's mid-40s, and adolescence's sickness rate has the trend of rising.Along with the raising of quality of life, the sickness rate of rectal cancer increases year by year, have the sickness rate of report colorectal cancer (colon cancer+rectal cancer) to rank the 3rd (front two is pulmonary carcinoma and gastric cancer), the sickness rate to colorectal cancer in 2015 may exceed the sickness rate of pulmonary carcinoma and gastric cancer, ranks first.The annual new patients with colorectal cancer of sending out in the whole world is up to 930,000, and in the annual new cases of China up to 13-16 ten thousand people, in digestive tract tumor, the sickness rate of colorectal cancer is only second to gastric cancer; At the current morbidity rate of colorectal cancer of China up to 46.8/10 ten thousand; Colorectal cancer has become one of China's three large cancers, and its sickness rate just increases progressively with the speed spiral of 4.2%, far surpasses the international standard of 2%; China colorectal cancer morbidity also have an obvious feature: age of onset with 40-60 year between in the majority, average age of onset is 48.3 years old, early 10-15 more whole than westerner, more more common than American-European China youth patient, the PATIENTS WITH LARGE BOWEL of less than 30 years old is much.

The cause of disease of rectal cancer is still not fully aware of at present, and its morbidity is relevant with social environment, dietary habit, inherited genetic factors etc.Basic high risk factor of generally acknowledging is that Animal fat and protein are taken in too high at present, dietary fiber Deficiency of Intake.Rectal cancer clinically early stage often asymptomatic or symptom, without special, does not thus often draw attention.Most of patients can have bowl evacuation habit change and have blood in stool in early days, and present just frequency, defecation and feel not to the utmost, have blood in stool, color is scarlet, is often mistakened as and makes hemorrhoid and ignore.When cancerous protuberance development increases, can occur constipation when infiltrating enteric cavity one week, difficult defecation, feces attenuate, and the chronic obstruction symptom such as accompany inferior belly gas pain uncomfortable.When cancerous protuberance involves anal canal or perianal, except for except having blood in stool, often have proctalgia and anal orifice to have block to give prominence to, most of patients with just frequently and defecation feel not to the utmost.When cancerous protuberance invade and anal sphincter time, can faecal incontinence be there is.When there is lymph metastasis, inguinal region can occur then merging by the lymph node that enlargement, matter are hard agglomerating.When lymphatic metastasis infiltrates obturator nerve, intractable perineal position pain can be there is and radiate to femoribus internus.These are all the Late manifestations of cancerous protuberance.

At present, the medicament for the treatment of rectal cancer has, publication number CN 104491078 A(application number 201410718135.1) patent document discloses a kind of Chinese medicinal tablet for the treatment of rectal cancer, be made up of the raw material of following mass fraction: Herba Hedyotidis Diffusae 30-40 part, Radix Angelicae Sinensis 10-25 part, Radix Astragali 20-40 part, Herba Dianthi 30-40 part, Fructus Caricae 10-18 part, Semen Persicae 5-20 part, Ramulus Cinnamomi 15-25, Rhizoma Corydalis 10-20, Caulis Sargentodoxae 20-30, Herba Galii Teneri 10-25, Semen Platycladi 20-30 part, Folium Isatidis 5-15 part, Radix Glycyrrhizae 2-20 part, Caulis Akebiae 15-30 part.Publication number CN 104352781 A(application number 201410563828.8) patent document discloses a kind of Chinese medicine preparation and preparation method for the treatment of rectal cancer, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Semen Platycladi 32-55 part, Fructus Artocarpi Heterophylli 29-53 part, Rhizoma Picrorhizae 28-52 part, Herba Bulbophylli inconspicui 25-49 part, carambola 25-49 part, Herba Polygoni Runcinati 23-45 part, Bauhinia purpurea 20-44 part, good rattan 18-42 part, rub Bai Ye 17-41 part, bigarabe 17-41 part, purple bubble 16-40 part, Folium Nelumbinis 15-39 part, Fructus Caricae 13-35 part, Radix Puerariae 13-31 part, Herba Bidentis Bipinnatae 11-29 part, Fructus Chebulae 5-29 part.Publication number CN 102526197 A(application number 201210036469.1) patent document discloses a kind of medicine for the treatment of rectal cancer, cervical cancer, be the obtained medicament of crude drug by the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 4-10, Borax 7-12, Fructus Cnidii 3-5, Olibanum 10-15, Venenum Bufonis 3-5, Myrrha 8-13, Radix Sophorae Flavescentis 10-14, Fructus Gleditsia 12-15, Ramulus Cinnamomi 10-15, Borneolum Syntheticum 12-16, catechu 10-13, Calomelas 6-10, Alumen 15-20.

At present, treatment rectal cancer adopts doctor trained in Western medicine excision usually, but most patient with operation later stage easily recurs, and easily damages anus.And intravenously administrable or oral western medicine all cannot cure rectal cancer.Though chemicotherapy has certain short term effect, have obvious toxicity, cause the immunity degradation of patient, and chemicotherapy also can not kill all cancerous cell, and kill a lot of normal cell.The most of uncertain therapeutic efficacy of current Chinese medicine is cut.

Summary of the invention

For the deficiencies in the prior art, an object of the present invention is to provide a kind of Chinese medicine for the treatment of rectal cancer, adopt Chinese crude drug comparatively common in the localities as raw material, for the pathomechanism of rectal cancer, have effect of mass dissipating and swelling eliminating, regulating the flow of QI to dissipate blood stasis, heat-clearing and toxic substances removing, another object of the present invention is to provide the preparation method of above-mentioned Chinese medicine.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

Treat a Chinese medicine for rectal cancer, take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 12-16 part; Fructus Perillae Frutescentis 9-13 part; Folium et Ramulus Callicarpae nudiflorae 11-15 part; Radix Sanguisorbae 6-9 part; Radix Euscaphis japonicae 10-17 part; Radix Aucklandiae 8-16 part; Semen Lagenariae sicerariae 11-16 part; Rhizoma Coptidis 12-18 part; Rhizoma Imperatae 10-16 part; Fructus Akebiae 13-19 part; Rhizoma panacis majoris 8-15 part; Herba Houttuyniae 9-14 part; Radix Raphani 11-16 part.

Treat a Chinese medicine for rectal cancer, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 13-15 part; Fructus Perillae Frutescentis 10-12 part; Folium et Ramulus Callicarpae nudiflorae 12-14 part; Radix Sanguisorbae 7-8 part; Radix Euscaphis japonicae 12-15 part; Radix Aucklandiae 11-13 part; Semen Lagenariae sicerariae 13-15 part; Rhizoma Coptidis 14-16 part; Rhizoma Imperatae 12-14 part; Fructus Akebiae 15-17 part; Rhizoma panacis majoris 10-13 part; Herba Houttuyniae 11-13 part; Radix Raphani 13-15 part.

Treat a Chinese medicine for rectal cancer, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 14 parts; Fructus Perillae Frutescentis 11 parts; Folium et Ramulus Callicarpae nudiflorae 13 parts; Radix Sanguisorbae 7.5 parts; Radix Euscaphis japonicae 13 parts; The Radix Aucklandiae 12 parts; Semen Lagenariae sicerariae 14 parts; Rhizoma Coptidis 15 parts; Rhizoma Imperatae 13 parts; Fructus Akebiae 16 parts; Rhizoma panacis majoris 12 parts; Herba Houttuyniae 12 parts; Radix Raphani 14 parts.

Present invention also offers the preparation method Chinese medicine of above-mentioned treatment rectal cancer being made pharmaceutically acceptable pill, granule, capsule, tablet and oral liquid.

The preparation method of the Chinese medicine pill of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), pill (preferably make the pill that diameter is 3-5mm, be more preferably and make the pill that diameter is 4mm) is made by the processing method of pill.

Instructions of taking: each 6-8 ball, every day 3 times, 15 days courses for the treatment of.

The preparation method of the Chinese medicine granule of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), add simple syrup, mix homogeneously, make uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

According to preparation method recited above, the consumption of the preferred simple syrup of step (5) is the 10%-20% of thick paste quality, and the consumption being more preferably simple syrup is 15% of thick paste quality.

Instructions of taking: each 1 parcel, takes after dissolving by the warm water of 35-45 DEG C, every day 3 times, 15 days courses for the treatment of.

The preparation method of the Chinese medicine capsule of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), dry, pulverize, obtain medicated powder;

(6) step (5) gained medicated powder is made capsule (preferably make capsule by the specification of 0.4-0.6g/ grain, be more preferably and make capsule by the specification of 0.5g/ grain).

Instructions of taking: each 2-3 grain, every day 3 times, 15 days courses for the treatment of.

The preparation method of the Chinese medicine tablet of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.20-1.30(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.23-1.27, be more preferably and be concentrated into the thick paste that relative density is 1.25), sieve, make granule, drying, is pressed into tablet, sugar coating.

Instructions of taking: each 2-4 sheet, every day 3 times, 15 days courses for the treatment of.

The preparation method of the Chinese medicine oral liquid of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mix homogeneously, be concentrated into 1/2 of original volume, add sodium benzoate and correctives, mixing, sterilize 10-20 minute (preferably sterilization 13-17 minute, be more preferably sterilization 15 minutes), carry out sterile packaged with the dosage often propping up 6ml.

According to preparation method recited above, the consumption of step (5) preferred sodium benzoate is the 0.1%-0.3% of concentrated solution quality, and the consumption being more preferably sodium benzoate is 0.2% of concentrated solution quality.

Instructions of taking: each 1, every day 3 times, 15 days courses for the treatment of.

The pharmacological effect of each crude drug is respectively:

Flos Lonicerae: sweet in the mouth, cold in nature.Return lung, the heart, stomach warp.For the flower that dry flower or the band of caprifoliaceae plant Radix Ophiopogonis are just opened.There is heat-clearing and toxic substances removing, effect of wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat, various febrile disease (as fever of the body, dermexanthesis, sending out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain).

Fructus Perillae Frutescentis: acrid in the mouth, warm in nature.Return lung, spleen, large intestine channel.For the fruit of Labiatae Perilla plant common perilla.Seed oil is containing left-handed perillaldehyde, ergomaketon, matsutakealcohol and left-handed linalool.Fatty oil in seed, main is linolein and tripalmitin, in addition, also containing alpha-linolenic acid in seed.There is lowering the adverse-rising QI and dispelling phlegm, effect of loosening bowel to relieve constipation.For cough with dyspnea phlegm dyspnea, stagnation of QI constipation.

Folium et Ramulus Callicarpae nudiflorae: puckery, micro-pungent, micro-hardship, property is put down.GUIXIN warp.For the leaf of Verenaceae Callicarpa plant Callicarpa nudiflora.Containing flavone, tannin, volatile oil and sugar etc., the effective ingredient that stops blooding in leaf is a kind of polysaccharide, can obtain arabinose after acid hydrolysis, galactose etc.There is dissipating blood stasis hemostasis, effect of removing toxic substances and promoting subsidence of swelling.For epistaxis, hemoptysis, spit blood, have blood in stool, traumatic injury congestive edema, traumatic hemorrhage, burn due to hot liquid or fire, sore festers.

Radix Sanguisorbae: bitter in the mouth, acid, puckery, cold nature.Return liver, large intestine channel.For the dry root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.There is cooling blood for hemostasis, effect of removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.

Radix Euscaphis japonicae: bitter in the mouth, micro-pungent, property is put down.Return liver, spleen, kidney channel.For root or the root bark of the wild crow Chinese toon of Staphyleaceae wild crow Chinese toon platymiscium.There is expelling pathogenic wind from the body surface, effect of clearing away heat-damp and promoting diuresis.For headache due to invasion of exogenous pathogens, lumbago due to pathogenic wind-dampness, dysentery, has loose bowels, traumatic injury.

The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.For the dry root of the feverfew Radix Aucklandiae.There are promoting the circulation of QI to relieve pain, effect of strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.

Semen Lagenariae sicerariae: sweet in the mouth, property is put down.For the seed of Cucurbitaceae gourd calabash and calabash courd.Containing egg Bethune matter 38.27%, oil 48.6%, sugar 5.2%.The composition of protein has 18 seed amino acids to comprise all essential amino acids, Palmic acid, palmitoleic acid, stearic acid, and oleic acid and linoleic acid are main fatty acid; Sugar mainly contains rhamnose, fructose, galactose, sucrose, Raffinose and stachyose, also containing the cruel inhibitor LLTI-I of Trypsin, II, III.There is heat-clearing and toxic substances removing, effect of reducing swelling and alleviating pain.For pneumonia, acute appendicitis, bud pain.

Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.For the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.There is heat clearing and damp drying, effect of eliminating fire and detoxication.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.

Rhizoma Imperatae: sweet in the mouth, cold in nature.Return lung, stomach, urinary bladder channel.For the dry rhizome of grass Herba Imperatae, Arundoin, Coixol, fernenol, simiarenol, Isoarborinol, Anemonin, also containing sterols: stigmasterol, cupreol, campesterol, saccharide, volume sucrose, glucose and a small amount of fructose, xylose, simple acids: citric acid, oxalic acid and malic acid.There is cooling blood for hemostasis, effect of heat-clearing and toxic substances removing.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria, acute nephritis edema, dysuria, gastric heat is vomitted the sound of vomiting, coughs.

Fructus Akebiae: mildly bitter flavor, property is put down.Return liver, stomach, urinary bladder channel.For the mature fruit of Lardizabalaceae Three Akebia Decne Species Caulis Akebiae, threeleaf akebia or white BENTONG.There is dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, effect of diuresis.For stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor.

Rhizoma panacis majoris: bitter in the mouth, sweet, cold in nature.For the rhizome of araliaceae ginseng plant's Rhizoma panacis majoris.Containing multiple Saponin, belong to having of oleanane type: panax japonicus Saponin Na, V (being namely ginsenoside-Ro), oleanolic acid-28-O-β-D-glucopyanoside, oleanolic acid-3-O-β-D-(6-O-methyl)-glucopyra alditol ginseng glycoside, panax japonicus Saponin Iva methyl ester, 3-O-β-D-glucopyanoside.Have clearing away heat and nourishing YIN, dissipating blood stasis stops blooding, effect of reducing swelling and alleviating pain.For calentura excessive thirst, deficiency of YIN cough due to lung-heat, hemoptysis, spit blood, epistaxis, has blood in stool, hematuria, metrorrhagia, traumatic hemorrhage, and traumatic injury wound is swollen, rheumatic arthralgia, stomachache, menoxenia, acute toothache, laryngopharynx swelling and pain, sore and toxic.

Herba Houttuyniae: acrid in the mouth, cold nature.Return lung meridian.For fresh herb or the dry aerial parts of saururaceae plant houttuynia cordata.There is heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, effect of inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.

Radix Raphani: acrid in the mouth, sweet, cool in nature; Ripe person's sweet in the mouth, property is put down.Return spleen, stomach, lung, large intestine channel.For fresh of Cruciferae Radix Raphani platymiscium Radix Raphani.Containing sugar mainly glucose, sucrose and fructose.Each several part also records coumaric acid, caffeic acid, ferulic acid, phenylpyruvic acid, gentisic acid, hydroxy benzoic acid and several amino acids.Fresh containing methanthiol 7.75mg%, the nearly 20mg% of vitamin C, containing manganese 0.41mg%, boron is about 7mg% (dry weight), again containing raphanusin.Have and help digestion, the therapeutic method to keep the adverse QI flowing downwards, reduce phlegm, hemostasis, quenches one's thirst, effect of diuresis.For dyspepsia, food stagnation distension, acid regurgitation, diarrhoea, dysentery, phlegm-heat cough, discomfort in the throat, hemoptysis, hematemesis and epistaxis, has blood in stool, and quenches one's thirst, stranguria with turbid discharge; External treatment skin infection, damage congestive edema, scalds and chilblain.

Beneficial effect of the present invention is mainly reflected in:

1, formula Chinese crude drug of the present invention is easy to get, and each medical material all has no side effect, and long-term taking also can not damage internal organs, and drug dependence is less, and medication is safer.

2, the present invention can correct some imbalance of body, effectively improves diet and the sleep state of patient, strengthens the body constitution of patient, have good effect, reduce the chance of recurrence and transfer to enhancing immunologic function.

3, the present invention adopts that pure natural draft Chinese medicine unique formula and technique are refining to be formed, less to the injury of healthy cell, significantly improves survival period and the life quality of patient.

4, the present invention follows the principle of tcm treatment according to syndrome differentiation, merges a few taste natural Chinese medicine, has effect of mass dissipating and swelling eliminating, regulating the flow of QI to dissipate blood stasis, heat-clearing and toxic substances removing, determined curative effect, reduces the harm that rectal cancer brings, and clinic is promoted.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.

embodiment 1treat a Chinese medicine for rectal cancer, take off and state primary raw material and be prepared from (getting 60g for every part): Flos Lonicerae 12 parts; Fructus Perillae Frutescentis 9 parts; Folium et Ramulus Callicarpae nudiflorae 11 parts; Radix Sanguisorbae 6 parts; Radix Euscaphis japonicae 10 parts; The Radix Aucklandiae 8 parts; Semen Lagenariae sicerariae 11 parts; Rhizoma Coptidis 12 parts; Rhizoma Imperatae 10 parts; Fructus Akebiae 13 parts; Rhizoma panacis majoris 8 parts; Herba Houttuyniae 9 parts; Radix Raphani 11 parts.

The preparation method of the Chinese medicine pill of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, cross 140 mesh sieves;

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of 75% of 5 times amount, soak 4 hours, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 4 hours, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 35 minutes, filters, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.15(25 DEG C) thick paste, make by the processing method of pill the pill that diameter is 4mm.

Instructions of taking: each 6-8 ball, every day 3 times, 15 days courses for the treatment of.

embodiment 2treat a Chinese medicine for rectal cancer, take off and state primary raw material and be prepared from (getting 25g for every part): Flos Lonicerae 16 parts; Fructus Perillae Frutescentis 13 parts; Folium et Ramulus Callicarpae nudiflorae 15 parts; Radix Sanguisorbae 9 parts; Radix Euscaphis japonicae 17 parts; The Radix Aucklandiae 16 parts; Semen Lagenariae sicerariae 16 parts; Rhizoma Coptidis 18 parts; Rhizoma Imperatae 16 parts; Fructus Akebiae 19 parts; Rhizoma panacis majoris 15 parts; Herba Houttuyniae 14 parts; Radix Raphani 16 parts.

The preparation method of the Chinese medicine granule of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, cross 140 mesh sieves;

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of 75% of 5 times amount, soak 4 hours, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 4 hours, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 35 minutes, filters, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.15(25 DEG C) thick paste, add simple syrup (consumption is 15% of thick paste quality), mix homogeneously, makes uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

Instructions of taking: each 1 parcel, takes after dissolving by the warm water of 35-45 DEG C, every day 3 times, 15 days courses for the treatment of.

model case onebian XX, man, 32 years old, people from Jining City in Shandong Province.Without there is stool band color under obvious inducement before 2 years, local hospital is diagnosed as mixed hemorrhoid, implements anti-inflammatory treatment, treats more than ten day, poor effect.Afterwards, go to hospital to do detailed inspection further, intestinal mirror rectal lesion, pathologic finding shows rectal cancer.So implement operation, Post operation rehabilitation after half a year chemotherapy, after check.After similar 1 year, sensuously an awful ache in the belly suddenly one day, lies up and also cannot alleviate, and after being sent to hospital, checking and find rectal cancer recurrence.

Take 2 courses for the treatment of of Chinese medicine granule of gained of the present invention treatment rectal cancer, symptom is clearly better, and health also energetically youngster, sleep quality improves.After continuing to take 2 courses for the treatment of, all malaise symptoms disappear, and check and find to reach clinical cure.Following up a case by regular visits to 1 year so far without recurrence, there are not other malaise symptoms in health yet.

embodiment 3treat a Chinese medicine for rectal cancer, take off and state primary raw material and be prepared from (getting 40g for every part): Flos Lonicerae 13 parts; Fructus Perillae Frutescentis 10 parts; Folium et Ramulus Callicarpae nudiflorae 12 parts; Radix Sanguisorbae 7 parts; Radix Euscaphis japonicae 12 parts; The Radix Aucklandiae 11 parts; Semen Lagenariae sicerariae 13 parts; Rhizoma Coptidis 14 parts; Rhizoma Imperatae 12 parts; Fructus Akebiae 15 parts; Rhizoma panacis majoris 10 parts; Herba Houttuyniae 11 parts; Radix Raphani 13 parts.

The preparation method of the Chinese medicine capsule of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, cross 140 mesh sieves;

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of 75% of 5 times amount, soak 4 hours, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 4 hours, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 35 minutes, filters, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.15(25 DEG C) thick paste, dry, pulverize, obtain medicated powder;

(6) step (5) gained medicated powder is made capsule (specification by 0.5g/ grain).

Instructions of taking: each 2-3 grain, every day 3 times, 15 days courses for the treatment of.

embodiment 4treat a Chinese medicine for rectal cancer, take off and state primary raw material and be prepared from (getting 20g for every part): Flos Lonicerae 15 parts; Fructus Perillae Frutescentis 12 parts; Folium et Ramulus Callicarpae nudiflorae 14 parts; Radix Sanguisorbae 8 parts; Radix Euscaphis japonicae 15 parts; The Radix Aucklandiae 13 parts; Semen Lagenariae sicerariae 15 parts; Rhizoma Coptidis 16 parts; Rhizoma Imperatae 14 parts; Fructus Akebiae 17 parts; Rhizoma panacis majoris 13 parts; Herba Houttuyniae 13 parts; Radix Raphani 15 parts.

The preparation method of the Chinese medicine tablet of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, cross 140 mesh sieves;

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of 75% of 5 times amount, soak 4 hours, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 4 hours, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 35 minutes, filters, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.25(25 DEG C) thick paste, sieve, make granule, dry, be pressed into tablet, sugar coating.

Instructions of taking: each 2-4 sheet, every day 3 times, 15 days courses for the treatment of.

model case twothunder XX, female, 59 years old, people from Linyi .patient is many because of defecation frequency, is just with mucus, usually feels that before or after meals belly is swollen, defecates rare, go to toilet every day repeatedly, has pendant sense, pain after an action of the bowels.Rear pain is aggravated gradually, and the situation of abdominal distention is more and more obvious.Remove examination in hospital, result is diagnosed as rectal cancer, carries out rectum resection operation at random, carries out chemotherapy a couple of days.Less than half a year, Mrs Lei occurs uncomfortable, checks and finds result rectal cancer recurrence.

After taking 2 courses for the treatment of of Chinese medicine tablet of gained of the present invention treatment rectal cancer, all malaise symptoms all obtain alleviation in varying degrees.After continuing to take 2 courses for the treatment of, examination in hospital is gone not find the existence of cancerous cell.Follow up a case by regular visits to and within 1 year, learn and do not recur.

embodiment 5treat a Chinese medicine for rectal cancer, take off and state primary raw material and be prepared from (getting 10g for every part): Flos Lonicerae 14 parts; Fructus Perillae Frutescentis 11 parts; Folium et Ramulus Callicarpae nudiflorae 13 parts; Radix Sanguisorbae 7.5 parts; Radix Euscaphis japonicae 13 parts; The Radix Aucklandiae 12 parts; Semen Lagenariae sicerariae 14 parts; Rhizoma Coptidis 15 parts; Rhizoma Imperatae 13 parts; Fructus Akebiae 16 parts; Rhizoma panacis majoris 12 parts; Herba Houttuyniae 12 parts; Radix Raphani 14 parts.

The preparation method of the Chinese medicine oral liquid of above-mentioned treatment rectal cancer, step is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, cross 140 mesh sieves;

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of 75% of 5 times amount, soak 4 hours, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 4 hours, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 35 minutes, filters, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, step (1) gained juice and step (2) gained powder is added, mix homogeneously, be concentrated into 1/2 of original volume, add sodium benzoate and correctives, mixing, sterilize 15 minutes, carry out sterile packaged with the dosage often propping up 6ml.

Instructions of taking: each 1, every day 3 times, 15 days courses for the treatment of.

test example:in order to verify the curative effect of the Chinese medicine (embodiment 5) of the treatment rectal cancer of gained of the present invention, We conducted contrast test.Experiment select rectal cancer patient 250 people (get rid of 1. the age less than 18 years old or more than 65 years old, pregnant or women breast-feeding their children, allergic constitution or those who are allergic to this drug; 2. the severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hemopoietic system are associated with, psychotic; 3. do not meet inclusive criteria, cannot judge that curative effect etc. affects the treatment or safety judgement person), be divided into matched group and experimental group randomly, wherein experimental group has 150 people, and matched group has 100 people.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change.Experimental group: the Chinese medicine oral liquid taking gained of the present invention treatment rectal cancer, each 1, every day 3 times, 15 days courses for the treatment of.Matched group: take other drug (as anticancer pill ball, FUFANG BANMAO JIAONANG etc.), wherein, anticancer pill ball: oral, a 0.5-1g, 2 times on the one, takes after meal half an hour.FUFANG BANMAO JIAONANG: oral, one time 3,2 times on the one.Our every days same equal time, medication under square one, and the health of observing simultaneously, recording every group patient.Curative effect situation criterion: cure: after 4 courses for the treatment of, all malaise symptoms disappear, and reach clinical cure level, and do not recur within least one year.Effective: after 4 courses for the treatment of, all malaise symptoms are obviously eased.Invalid: after 4 courses for the treatment of, all malaise symptoms without any improvement or one month in recurrence.Wherein effectively comprise recovery from illness and effective.Take the matched group of other drug and take the Comparison of therapeutic that the present invention treats the experimental group of the Chinese medicine of rectal cancer, result is as shown in table 1:

Table 1

efficacy analysis:as can be seen from Table 1, take the inefficiency that the present invention treats the Chinese medicine of rectal cancer and be only 8%, cure rate up to 62.67%, effective percentage up to 92%, and take other drug have 23% inefficiency, cure rate only reaches 32%, and effective percentage is also only 77%.Experiment shows that the present invention treats the Chinese medicine of rectal cancer compared with other drug, and it is evident in efficacy, and cure rate is high, and inefficiency is low.

Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. treat a Chinese medicine for rectal cancer, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 12-16 part; Fructus Perillae Frutescentis 9-13 part; Folium et Ramulus Callicarpae nudiflorae 11-15 part; Radix Sanguisorbae 6-9 part; Radix Euscaphis japonicae 10-17 part; Radix Aucklandiae 8-16 part; Semen Lagenariae sicerariae 11-16 part; Rhizoma Coptidis 12-18 part; Rhizoma Imperatae 10-16 part; Fructus Akebiae 13-19 part; Rhizoma panacis majoris 8-15 part; Herba Houttuyniae 9-14 part; Radix Raphani 11-16 part.

2. the Chinese medicine for the treatment of rectal cancer according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 13-15 part; Fructus Perillae Frutescentis 10-12 part; Folium et Ramulus Callicarpae nudiflorae 12-14 part; Radix Sanguisorbae 7-8 part; Radix Euscaphis japonicae 12-15 part; Radix Aucklandiae 11-13 part; Semen Lagenariae sicerariae 13-15 part; Rhizoma Coptidis 14-16 part; Rhizoma Imperatae 12-14 part; Fructus Akebiae 15-17 part; Rhizoma panacis majoris 10-13 part; Herba Houttuyniae 11-13 part; Radix Raphani 13-15 part.

3. the Chinese medicine for the treatment of rectal cancer according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 14 parts; Fructus Perillae Frutescentis 11 parts; Folium et Ramulus Callicarpae nudiflorae 13 parts; Radix Sanguisorbae 7.5 parts; Radix Euscaphis japonicae 13 parts; The Radix Aucklandiae 12 parts; Semen Lagenariae sicerariae 14 parts; Rhizoma Coptidis 15 parts; Rhizoma Imperatae 13 parts; Fructus Akebiae 16 parts; Rhizoma panacis majoris 12 parts; Herba Houttuyniae 12 parts; Radix Raphani 14 parts.

4., according to the Chinese medicine of the arbitrary described treatment rectal cancer of claim 1-3, it is characterized in that, make pharmaceutically acceptable pill, preparation method is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), pill (preferably make the pill that diameter is 3-5mm, be more preferably and make the pill that diameter is 4mm) is made by the processing method of pill.

5., according to the Chinese medicine of the arbitrary described treatment rectal cancer of claim 1-3, it is characterized in that, make pharmaceutically acceptable granule, preparation method is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), add simple syrup, mix homogeneously, make uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

6. preparation method according to claim 5, is characterized in that: the consumption of the preferred simple syrup of step (5) is the 10%-20% of thick paste quality, and the consumption being more preferably simple syrup is 15% of thick paste quality.

7., according to the Chinese medicine of the arbitrary described treatment rectal cancer of claim 1-3, it is characterized in that, make pharmaceutically acceptable capsule, preparation method is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.17, be more preferably and be concentrated into the thick paste that relative density is 1.15), dry, pulverize, obtain medicated powder;

(6) step (5) gained medicated powder is made capsule (preferably make capsule by the specification of 0.4-0.6g/ grain, be more preferably and make capsule by the specification of 0.5g/ grain).

8., according to the Chinese medicine of the arbitrary described treatment rectal cancer of claim 1-3, it is characterized in that, make pharmaceutically acceptable tablet, preparation method is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mixing, being concentrated into relative density is 1.20-1.30(25 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.23-1.27, be more preferably and be concentrated into the thick paste that relative density is 1.25), sieve, make granule, drying, is pressed into tablet, sugar coating.

9., according to the Chinese medicine of the arbitrary described treatment rectal cancer of claim 1-3, it is characterized in that, make pharmaceutically acceptable oral liquid, preparation method is as follows:

(1) by Radix Euscaphis japonicae, Herba Houttuyniae and Radix Raphani chopping, strand juice, elimination impurity, juice is for subsequent use;

(2) Fructus Akebiae is cut into slices, dry, pulverize, grind into powder, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) by Radix Sanguisorbae, Rhizoma Imperatae and Rhizoma panacis majoris section, be placed in container, add the alcoholic solution of the 70%-80% of 5 times amount, soak 3-5 hour, heating extraction 2-4 hour (preferred heating extraction 2.5-3.5 hour is more preferably heating extraction 3 hours), reclaim ethanol, filter, obtain filtrate;

(4) Radix Aucklandiae, Semen Lagenariae sicerariae and Rhizoma Coptidis are cleaned, be placed in container, soak 3-5 hour, be placed in marmite, add Flos Lonicerae, Fructus Perillae Frutescentis and Folium et Ramulus Callicarpae nudiflorae, decoct twice, each decoction 30-40 minute (preferably each decoction 33-37 minute, be more preferably each decoction 35 minutes), filter, merging filtrate;

(5) by step (3)-(4) gained filtrate mix homogeneously, add step (1) gained juice and step (2) gained powder, mix homogeneously, be concentrated into 1/2 of original volume, add sodium benzoate and correctives, mixing, sterilize 10-20 minute (preferably sterilization 13-17 minute, be more preferably sterilization 15 minutes), carry out sterile packaged with the dosage often propping up 6ml.

10. preparation method according to claim 9, is characterized in that: the consumption of step (5) preferred sodium benzoate is the 0.1%-0.3% of concentrated solution quality, and the consumption being more preferably sodium benzoate is 0.2% of concentrated solution quality.