CN104780937A - 涉及由多核苷酸编码的免疫原性多肽的新型初免-加强方案 - Google Patents

涉及由多核苷酸编码的免疫原性多肽的新型初免-加强方案 Download PDF

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Publication number
CN104780937A
CN104780937A CN201380044981.3A CN201380044981A CN104780937A CN 104780937 A CN104780937 A CN 104780937A CN 201380044981 A CN201380044981 A CN 201380044981A CN 104780937 A CN104780937 A CN 104780937A
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Chinese (zh)
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A.尼科西亚
R.科尔特斯
A.维特利
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GlaxoSmithKline Biologicals SA
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201380044981.3A 2012-07-05 2013-07-05 涉及由多核苷酸编码的免疫原性多肽的新型初免-加强方案 Pending CN104780937A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2012/063196 WO2014005643A1 (en) 2012-07-05 2012-07-05 Novel prime-boosting regimens involving immunogenic polypeptides encoded by polynucleotides
EPPCT/EP2012/063196 2012-07-05
PCT/EP2013/064286 WO2014006191A1 (en) 2012-07-05 2013-07-05 Novel prime-boosting regimens involving immunogenic polypeptides encoded by polynucleotides

Publications (1)

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CN104780937A true CN104780937A (zh) 2015-07-15

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US (3) US20150209420A1 (https=)
JP (1) JP6244358B2 (https=)
KR (1) KR20150038010A (https=)
CN (1) CN104780937A (https=)
AU (1) AU2013285398A1 (https=)
BR (1) BR112014033077A2 (https=)
CA (1) CA2878367A1 (https=)
DK (1) DK2869841T3 (https=)
EA (1) EA201492230A1 (https=)
ES (1) ES2895070T3 (https=)
HU (1) HUE056675T2 (https=)
IL (1) IL236414A0 (https=)
IN (1) IN2014KN03063A (https=)
LT (1) LT2869841T (https=)
MX (1) MX365391B (https=)
PT (1) PT2869841T (https=)
SG (1) SG11201408746XA (https=)
WO (2) WO2014005643A1 (https=)
ZA (1) ZA201500102B (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
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CN111386126A (zh) * 2017-10-25 2020-07-07 Nouscom股份公司 真核细胞系
WO2022042300A1 (zh) * 2020-08-25 2022-03-03 北京交通大学 一种针对呼吸道合胞病毒感染的组合疫苗及其诱导免疫应答的方法
CN114375199A (zh) * 2019-07-29 2022-04-19 皮尔布莱特研究所 非洲猪瘟疫苗
RU2794440C1 (ru) * 2020-08-25 2023-04-18 Бейджин Цзяотун Юниверсити Комбинированная вакцина против респираторно-синцитиальных вирусных (rsv) инфекций человека и способ индуцирования иммунного ответа с ее помощью
CN117304280A (zh) * 2023-11-28 2023-12-29 江苏瑞科生物技术股份有限公司 一种重组rsv f蛋白及其应用

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KR102236497B1 (ko) 2013-04-25 2021-04-06 얀센 백신스 앤드 프리벤션 비.브이. 안정화된 가용성 예비융합 ｒｓｖ ｆ 폴리펩타이드
MX384992B (es) * 2014-06-13 2025-03-14 Glaxosmithkline Biologicals Sa Combinaciones inmunógenas.
PT3188753T (pt) 2014-09-03 2020-03-25 Bavarian Nordic As Métodos e composições para induzir imunidade protetora contra infeção por filovírus
CA2960096A1 (en) 2014-09-03 2016-03-10 Bavarian Nordic A/S Methods and compositions for enhancing immune responses
US9630994B2 (en) 2014-11-03 2017-04-25 University Of Washington Polypeptides for use in self-assembling protein nanostructures
WO2016184822A1 (en) 2015-05-15 2016-11-24 Curevac Ag Prime-boost regimens involving administration of at least one mrna construct
EA039065B1 (ru) 2015-07-07 2021-11-29 Янссен Вэксинс Энд Превеншн Б.В. Вакцина против rsv
US10457708B2 (en) 2015-07-07 2019-10-29 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
JP7233928B2 (ja) 2016-04-05 2023-03-07 ヤンセン ファッシンズ アンド プリベンション ベーフェー Ｒｓｖに対するワクチン
IL262108B2 (en) 2016-04-05 2023-04-01 Janssen Vaccines Prevention B V Soluble pre-fusion rsv f proteins are stabilized
JP7053491B2 (ja) * 2016-05-02 2022-04-12 ヤンセン ファッシンズ アンド プリベンション ベーフェー 治療用ｈｐｖワクチン組み合わせ
CN109311946A (zh) 2016-05-30 2019-02-05 扬森疫苗与预防公司 稳定化的融合前rsv f蛋白
EP3484507A1 (en) 2016-07-15 2019-05-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against a marburg virus infection
HUE073526T2 (hu) 2017-04-04 2026-01-28 Univ Washington Önmagát összeállító fehérje nanostruktúrák, amelyek paramyxovírus és/vagy pneumovírus F fehérjéket jelenítenek meg és azok használata
EP3606553A1 (en) 2017-04-06 2020-02-12 Janssen Vaccines & Prevention B.V. Mva-bn and ad26.zebov or ad26.filo prime-boost regimen
AU2018267971A1 (en) 2017-05-17 2019-11-07 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
WO2018210871A1 (en) * 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
SG11202001458SA (en) 2017-09-15 2020-03-30 Janssen Vaccines & Prevention Bv Method for the safe induction of immunity against rsv
WO2019094396A1 (en) * 2017-11-07 2019-05-16 Nektar Therapeutics Immunotherapeutic combination for treating cancer
WO2019169120A1 (en) 2018-02-28 2019-09-06 University Of Washington Self-asssembling nanostructure vaccines
MX2021005607A (es) 2018-11-13 2021-06-30 Janssen Vaccines & Prevention Bv Proteinas f de prefusion del vrs estabilizadas.

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111386126A (zh) * 2017-10-25 2020-07-07 Nouscom股份公司 真核细胞系
CN111386126B (zh) * 2017-10-25 2024-01-30 Nouscom股份公司 真核细胞系
CN114375199A (zh) * 2019-07-29 2022-04-19 皮尔布莱特研究所 非洲猪瘟疫苗
WO2022042300A1 (zh) * 2020-08-25 2022-03-03 北京交通大学 一种针对呼吸道合胞病毒感染的组合疫苗及其诱导免疫应答的方法
RU2794440C1 (ru) * 2020-08-25 2023-04-18 Бейджин Цзяотун Юниверсити Комбинированная вакцина против респираторно-синцитиальных вирусных (rsv) инфекций человека и способ индуцирования иммунного ответа с ее помощью
US12472243B2 (en) 2020-08-25 2025-11-18 Beijing Jiaotong University Combined vaccine against human respiratory syncytial virus (RSV) infections and method thereof for inducing immune response
CN117304280A (zh) * 2023-11-28 2023-12-29 江苏瑞科生物技术股份有限公司 一种重组rsv f蛋白及其应用
CN117304280B (zh) * 2023-11-28 2024-04-16 江苏瑞科生物技术股份有限公司 一种重组rsv f蛋白及其应用

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MX365391B (es) 2019-05-31
PT2869841T (pt) 2021-10-28
WO2014005643A1 (en) 2014-01-09
US20240091338A1 (en) 2024-03-21
IL236414A0 (en) 2015-02-26
KR20150038010A (ko) 2015-04-08
JP6244358B2 (ja) 2017-12-06
DK2869841T3 (da) 2021-10-25
HUE056675T2 (hu) 2022-02-28
WO2014006191A1 (en) 2014-01-09
CA2878367A1 (en) 2014-01-09
MX2014016119A (es) 2015-09-23
LT2869841T (lt) 2021-11-25
ZA201500102B (en) 2017-09-27
SG11201408746XA (en) 2015-01-29
JP2015526403A (ja) 2015-09-10
ES2895070T3 (es) 2022-02-17
IN2014KN03063A (https=) 2015-05-08
BR112014033077A2 (pt) 2017-08-01
US20150209420A1 (en) 2015-07-30
EA201492230A1 (ru) 2015-06-30
AU2013285398A1 (en) 2015-02-05
US20180256704A1 (en) 2018-09-13

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Application publication date: 20150715