CN104758216A - Nutritional anti-inflammatory mouth rinse and preparation method thereof - Google Patents

Abstract

The invention discloses nutritional anti-inflammatory mouth rinse. The mouth rinse is prepared from the following components in percentage by mass: 90 percent of noni extract, 0.005-0.008 percent of menthol, 1.2-1.5 percent of dipotassium glycyrrhizinate, 3-5 percent of sorbitol, 0.008-0.01 percent of potassium sorbate, a proper amount of potassium bicarbonate and the balance of pure. The invention further discloses a method for preparing the nutritional anti-inflammatory mouth rinse. The method comprises the following steps: dissolving and uniformly mixing the components, and regulating pH to about 5.5; and filtering and sterilizing to obtain a finished product. The mouth rinse is rich in nutrition, contains vitamins, amino acids, minerals and multiple phytochemicals, can be used for diminishing inflammation, inhibiting bacteria, removing odor and preventing leaving stains on gum, and is fresh and delicious.

Description

A kind of nutrition antiinflammatory gargarism and preparation method thereof

Technical field

The invention belongs to technical field of food biotechnology, relate to a kind of nutrition antiinflammatory gargarism, the invention still further relates to the preparation method of this kind of nutrition antiinflammatory gargarism.

Background technology

Noni (noni), have another name called Morinda Citifolia (Morinda citrifolia Linn), Solanum pseudo-capsicumvar diflorum (Vell.)Bitter or India Fructus Mori, it is a kind of tropical evergreen broad-leaved dungarunga for many years of rising in island, the South Pacific Ocean, Rubiaceae Morinda plant, is mainly distributed in the ground such as Hainan Island, the Xisha Islands and the island of Taiwan in China.The history that noni is applied existing more than 2000 years as a kind of traditional medicinal plants by Polynesia aborigines, there is the title of " magical fruit " and " present that God vouchsafes ", its leaf, root, skin and fruit all have medicine and health care and are worth, to treatment inflammation, flu, headache, fever, rheumatic arthritis, fracture, sprain, the disease effects such as dermatosis, dyspepsia is obvious.Modern study existing more than 60 years of noni, in Morinda Citrifolia juice, isolation identification goes out 160 Multiple components, comprise essential amino acid, vitamin, mineral and multiple physiologically active ingredient, and celo rather former, the important functional composition such as polysaccharide, anthraquinone, terpenes, coumarin.

Japanese scholars is separated and obtains the materials such as compound (comprising 1 new anthraquinones, 2 sugar fatty acid esters, 2 glucofuranose bases) from the methanolic extract of Noni fruit, in Mice Body, all show effective anti-inflammatory activity.Hamburg, Germany university scholar effectively can reduce the pain and joint injury that cause inflammation with the ethanol extraction of noni mellow fruit, American scholar also has Noni extract and composition damnacanthal thereof to can be used as preventive and the therapeutic agent of gastroesophagitis disease, the research such as Murray compares the effectiveness that noni and sodium hypochlorite and chlorhexidine remove tooth tube wall pollution layer, domestic many various focusing depths represented Finding cases suck Morinda Citrifolia juice antiinflammatory and analgesic activity, does not go on the market at present with the rinsing the mouth product of Noni fruit goods manufacture.

The product of exploitation gargarism is in the market utilize chlorhexidine and its esters mostly, chlorhexidine and its esters can not eat, must tell after rinsing the mouth, and after rinsing the mouth, chlorhexidine is very easily left a trace on tooth, not easy-clear again, brings hidden danger to the health of people, causes very large injury also to the attractive in appearance of oral cavity.For this reason, the noni gargarism developing natural health is very necessary.The noni gargarism of natural health is nutritious, containing vitamin, aminoacid, mineral and many phytochemistries element, an inherently good health drink, it can not only antiinflammatory, antibacterial, can not cause damage to the gingiva of inflammation, and refrigerant, good to eat, delicious.Not only for people provide a kind of noni rinsing the mouth beverage novel extremely easily, also for valuable promise Buddhist nun comprehensive utilization of resources opens new approach, for the healthy of masses provides a product having the market competitiveness.About this series products, there is not been reported at present, is worth carrying out research promotion.

Summary of the invention

The object of this invention is to provide a kind of nutrition antiinflammatory gargarism, solving existing gargarism can not eat, and after rinsing the mouth, medicine leaves the vestige of not easy-clear on tooth, to the problem causing very major injury attractive in appearance in oral cavity.

Another object of the present invention is to provide the preparation method of above-mentioned nutrition antiinflammatory gargarism.

The technical solution adopted in the present invention is, a kind of nutrition antiinflammatory gargarism, composed of the following components according to mass percent: 90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum, 1.2% ~ 1.5% glycyrrhizic acid dipotassium, 3% ~ 5% sorbitol, 0.008% ~ 0.01% potassium sorbate, appropriate potassium bicarbonate, surplus is pure water, and gross mass is 100%.

Another technical scheme of the present invention is, a kind of preparation method of above-mentioned nutrition antiinflammatory gargarism, implements according to following steps:

Step 1, preparation Noni fruit extracting solution;

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum, 1.2% ~ 1.5% glycyrrhizic acid dipotassium, 3% ~ 5% sorbitol, 0.008% ~ 0.01% potassium sorbate, appropriate potassium bicarbonate is added after abundant mixing, make the pH value to 5.5 of mixed liquor, finally add pure water to gross mass to 100%; Filter, filtrate 100 DEG C sterilization 20 minutes ~ 30 minutes, obtains noni nutrition antiinflammatory gargarism.

The invention has the beneficial effects as follows, this nutrition antiinflammatory gargarism selects Noni fruit extracting solution, Mentholum, glycyrrhizic acid dipotassium, sorbitol, potassium sorbate etc. to be raw material, mixes according to a certain percentage, and fill, sterilization obtain.First utilize the endogenous enzymes hydrolysis extraction of noni self, then utilize external enzyme and ethanol to extract by not extracting part in Noni fruit, water solublity and fat-soluble effective ingredient can be able to be extracted like this.Ethanol adopts edible ethanol, and mixed liquor adopts potassium bicarbonate to adjust pH deacidification, and potassium bicarbonate is a kind of food additive, meets healthy requirement.This nutrition antiinflammatory gargarism has antiinflammatory, sterilization, preventing decayed tooth, and nutrition is good to eat again, is a kind of gargarism of natural, hygiene and health.

Detailed description of the invention

Below in conjunction with detailed description of the invention, the present invention is described in detail.

Nutrition antiinflammatory gargarism of the present invention, composed of the following components according to mass percent: 90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum (as freshener), 1.2% ~ 1.5% glycyrrhizic acid dipotassium (as antibacterial), 3% ~ 5% sorbitol (as flavoring agent), 0.008% ~ 0.01% potassium sorbate (as antiseptic), appropriate potassium bicarbonate, surplus is pure water, and gross mass is 100%.

Nutrition antiinflammatory gargarism preparation method of the present invention, implement according to following steps:

Step 1, preparation Noni fruit extracting solution

1.1) by the fresh Noni fruit of Maturity seven to eighty per cant, with the soak with ozone solution 20 ~ 30 minutes of 1.0mg/L, wash twice, be filtered dry, put into airtight tank, room temperature natural fermentation is after 10 ~ 15 days, smash to pieces, be separated, obtain water solublity noni extract and noni marc;

1.2) by the noni marc that obtains above through smashing to pieces, with Noni fruit slag amount for benchmark, add the water mixing of 8 ~ 10 times of quality, add the pectase of 0.1%, the lipase of 0.02%, the acid protease of 0.04% more respectively, ordinary-temp hydrolysis 5-7 hour, 90 DEG C of enzyme denaturing, are separated, obtain enzymolysis solution and recrement;

1.3) by 1.2) the noni recrement (recrement comprises much hard fruit) that obtains, drain, shatter, mix with the edible ethanol of 50 ~ 70% according to the mass ratio of 1:6 ~ 8, soak 24 hours ~ 36 hours, filter, filtrate is 80 ± 5 DEG C of reflux, extract, and vacuum concentration also reclaims ethanol; Repeatedly extract twice, reclaim ethanol, merging filtrate, obtains concentrated solution;

1.4) merge above-mentioned water solublity noni extract, enzymolysis solution and concentrated solution, obtained concentration is the Noni fruit extracting solution of 1g/mL.

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum, 1.2% ~ 1.5% glycyrrhizic acid dipotassium, 3% ~ 5% sorbitol, 0.008% ~ 0.01% potassium sorbate, appropriate potassium bicarbonate is added after abundant mixing, make the pH value to 5.5 of mixed liquor, finally add pure water to gross mass to 100%; Filter, filtrate 100 DEG C sterilization 20 minutes ~ 30 minutes, obtains noni nutrition antiinflammatory gargarism.

Embodiment 1

Step 1, preparation Noni fruit extracting solution

1.1) by the fresh Noni fruit of Maturity seven to eighty per cant, with the soak with ozone solution 20 minutes of 1.0mg/L, washing twice, be filtered dry, put into airtight tank, room temperature natural fermentation, after 10 days, is smashed to pieces, is separated, obtains water solublity noni extract and noni marc;

1.2) by the noni marc that obtains above through smashing to pieces, with Noni fruit slag amount for benchmark, add the water mixing of 8 times of quality, add the pectase of 0.1%, the lipase of 0.02%, the acid protease of 0.04% more respectively, ordinary-temp hydrolysis 5 hours, 90 DEG C of enzyme denaturing, are separated, obtain enzymolysis solution and recrement;

1.3) by 1.2) the noni recrement (being much hard fruit) that obtains, drain, shatter, mix with the edible ethanol of 50% according to the mass ratio of 1:6, soak 24 hours, filter, filtrate is 80 ± 5 DEG C of reflux, extract, and vacuum concentration also reclaims ethanol; Repeatedly extract twice, reclaim ethanol, merging filtrate, obtains concentrated solution;

1.4) merge above-mentioned water solublity noni extract, enzymolysis solution and concentrated solution, obtained concentration is the Noni fruit extracting solution of 1g/mL.

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution adds 0.005% Mentholum, 1.2% glycyrrhizic acid dipotassium respectively, 3% sorbitol, 0.008% potassium sorbate, mix, add appropriate potassium bicarbonate adjustment pH of mixed to 5.5, finally add pure water to 100%, filter, filtrate 100 DEG C sterilization 20 minutes, obtains noni nutrition antiinflammatory gargarism.

Embodiment 2

Step 1, preparation Noni fruit extracting solution

1.1) by the fresh Noni fruit of Maturity seven to eighty per cant, with the soak with ozone solution 20 ~ 30 minutes of 1.0mg/L, washing twice, be filtered dry, put into airtight tank, room temperature natural fermentation, after 12 days, is smashed to pieces, is separated, obtains water solublity noni extract and noni marc;

1.2) by the noni marc that obtains above through smashing to pieces, with Noni fruit slag amount for benchmark, add the water mixing of 9 times of quality, add the pectase of 0.1%, the lipase of 0.02%, the acid protease of 0.04% more respectively, ordinary-temp hydrolysis 6 hours, 90 DEG C of enzyme denaturing, are separated, obtain enzymolysis solution and recrement;

1.3) by 1.2) the noni recrement (being much hard fruit) that obtains, drain, shatter, mix with the edible ethanol of 60% according to the mass ratio of 1:7, soak 30 hours, filter, filtrate is 80 ± 5 DEG C of reflux, extract, and vacuum concentration also reclaims ethanol; Repeatedly extract twice, reclaim ethanol, merging filtrate, obtains concentrated solution;

1.4) merge above-mentioned water solublity noni extract, enzymolysis solution and concentrated solution, obtained concentration is the Noni fruit extracting solution of 1g/mL.

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution adds 0.006% Mentholum, 1.3% glycyrrhizic acid dipotassium respectively, 4% sorbitol, 0.009% potassium sorbate, mix, add appropriate potassium bicarbonate adjustment pH of mixed to 5.5, finally add pure water to 100%, filter, filtrate 100 DEG C sterilization 25 minutes, just obtains noni nutrition antiinflammatory gargarism.

Embodiment 3

Step 1, preparation Noni fruit extracting solution

1.1) by the fresh Noni fruit of Maturity seven to eighty per cant, with the soak with ozone solution 20 ~ 30 minutes of 1.0mg/L, washing twice, be filtered dry, put into airtight tank, room temperature natural fermentation, after 15 days, is smashed to pieces, is separated, obtains water solublity noni extract and noni marc;

1.2) by the noni marc that obtains above through smashing to pieces, with Noni fruit slag amount for benchmark, add the water mixing of 10 times of quality, add the pectase of 0.1%, the lipase of 0.02%, the acid protease of 0.04% more respectively, ordinary-temp hydrolysis 7 hours, 90 DEG C of enzyme denaturing, are separated, and obtain enzymolysis solution and drain recrement;

1.3) by 1.2) noni that obtains drains recrement and mixes with the edible ethanol of 70% according to the mass ratio of 1:8, soak 36 hours, and filter, filtrate is 80 ± 5 DEG C of reflux, extract, and vacuum concentration also reclaims ethanol; Repeatedly extract twice, reclaim ethanol, merging filtrate, obtains concentrated solution;

1.4) merge above-mentioned water solublity noni extract, enzymolysis solution and concentrated solution, obtained concentration is the Noni fruit extracting solution of 1g/mL.

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution adds 0.008% Mentholum, 1.5% glycyrrhizic acid dipotassium respectively, 5% sorbitol, 0.01% potassium sorbate, mix, add appropriate potassium bicarbonate adjustment pH of mixed to 5.5, finally add pure water to 100%, filter, filtrate 100 DEG C sterilization 30 minutes, just obtains noni nutrition antiinflammatory gargarism.

Claims (3)

1. a nutrition antiinflammatory gargarism, it is characterized in that, composed of the following components according to mass percent: 90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum, 1.2% ~ 1.5% glycyrrhizic acid dipotassium, 3% ~ 5% sorbitol, 0.008% ~ 0.01% potassium sorbate, appropriate potassium bicarbonate, surplus is pure water, and gross mass is 100%.

2. a preparation method for nutrition antiinflammatory gargarism according to claim 1, is characterized in that, nutrition antiinflammatory gargarism preparation method of the present invention, implements according to following steps:

Step 1, preparation Noni fruit extracting solution;

Step 2, mixing, filtration, sterilization

Take each component in mass ratio:

90% Noni fruit extracting solution, 0.005% ~ 0.008% Mentholum, 1.2% ~ 1.5% glycyrrhizic acid dipotassium, 3% ~ 5% sorbitol, 0.008% ~ 0.01% potassium sorbate, appropriate potassium bicarbonate is added after abundant mixing, make the pH value to 5.5 of mixed liquor, finally add pure water to gross mass to 100%; Filter, filtrate 100 DEG C sterilization 20 minutes ~ 30 minutes, obtains noni nutrition antiinflammatory gargarism.

3. the preparation method of nutrition antiinflammatory gargarism according to claim 2, is characterized in that, in described step 1, the detailed process of preparation Noni fruit extracting solution is:

1.1) by the fresh Noni fruit of Maturity seven to eighty per cant, with the soak with ozone solution 20 ~ 30 minutes of 1.0mg/L, wash twice, be filtered dry, put into airtight tank, room temperature natural fermentation is after 10 ~ 15 days, smash to pieces, be separated, obtain water solublity noni extract and noni marc;

1.2) by the noni marc that obtains above through smashing to pieces, with Noni fruit slag amount for benchmark, add the water mixing of 8 ~ 10 times of quality, add the pectase of 0.1%, the lipase of 0.02%, the acid protease of 0.04% more respectively, ordinary-temp hydrolysis 5-7 hour, 90 DEG C of enzyme denaturing, are separated, obtain enzymolysis solution and recrement;

1.3) by 1.2) the noni recrement that obtains, drain, shatter, mix according to the mass ratio of 1:6 ~ 8 with the edible ethanol of 50 ~ 70%, soak 24 hours ~ 36 hours, filter, filtrate is 80 ± 5 DEG C of reflux, extract, and vacuum concentration also reclaims ethanol; Repeatedly extract twice, reclaim ethanol, merging filtrate, obtains concentrated solution;

1.4) merge above-mentioned water solublity noni extract, enzymolysis solution and concentrated solution, obtained concentration is the Noni fruit extracting solution of 1g/mL.