CN104758216B - A kind of nutrition anti-inflammatory gargle and preparation method thereof - Google Patents
A kind of nutrition anti-inflammatory gargle and preparation method thereof Download PDFInfo
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- CN104758216B CN104758216B CN201510191675.3A CN201510191675A CN104758216B CN 104758216 B CN104758216 B CN 104758216B CN 201510191675 A CN201510191675 A CN 201510191675A CN 104758216 B CN104758216 B CN 104758216B
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Abstract
It is composed of the following components according to mass percent the invention discloses a kind of nutrition anti-inflammatory gargle：90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5% dipotassium glycyrrhizinate, 3%~5% sorbierite, 0.008%~0.01% potassium sorbate, appropriate saleratus, surplus is pure water, and gross mass is 100%.The invention also discloses the preparation method of this kind of nutrition anti-inflammatory gargle, by each component by dissolving, mixing, regulation pH to 5.5 or so, then filter, sterilize, obtain finished product.The present invention gargle it is nutritious, containing vitamin, amino acid, mineral matter and many Phytochemistry element, it can not only anti-inflammatory, antibacterial, deodorization, spot, and refrigerant, tasty, delicious food are will not leave behind to gum.
Description
Technical field
The invention belongs to technical field of food biotechnology, it is related to a kind of nutrition anti-inflammatory gargle, the invention further relates to this kind battalion
Support the preparation method of anti-inflammatory gargle.
Background technology
Nuo Li (noni), also known as Morinda (Morinda citrifolia Linn), four seasons fruit or India mulberry fruit, are one
Kind rise in the tropical evergreen on the South Pacific Ocean island broad-leaved dungarunga, Rubiaceae Morinda plant, at Chinese main point for many years
It is distributed in the ground such as Hainan Island, the Xisha Islands and the island of Taiwan.Nuo Li is as a kind of traditional medicinal plant by Polynesia aborigines
Using existing more than 2000 years history, there is the title of " magical fruit " and " present that God vouchsafes ", its leaf, root, skin and fruit have
Have medicinal and health value, to treatment inflammation, flu, headache, fever, rheumatic arthritis, fracture, sprain, skin disease, digestion
The disease effects such as bad are obvious.The beautiful modern study of promise existing more than 60 years, in Morinda Citrifolia juice separation identify more than 160 kinds into
Point, including essential amino acid, vitamin, mineral matter and a variety of physiologically active ingredients, and the peaceful original of celo, polysaccharide, anthraquinone,
The critical function composition such as terpenes, cumarin.
Japanese scholars isolated compound (including 1 new anthraquinones, 2 from the methanolic extract of Noni fruit
Individual sugar fatty acid ester, 2 glucofuranose bases) etc. material, effective anti-inflammatory activity is all showed in Mice Body.Hamburg, Germany is big
Learning scholar can effectively be reduced to pain caused by inflammation and joint injury, American scholar with the ethanol extract of the beautiful mellow fruit of promise
Have Noni extract and its composition damnacanthal can as stomach oesophagus inflammation prophylactic and therapeutic agent, the research such as Murray compares
The beautiful validity that tooth tube wall pollution layer is removed with sodium hypochlorite and Chlorhexidine of promise, domestic many various focusing depths represented Finding cases mouthful
There are anti-inflammatory and analgesic activity containing Morinda Citrifolia juice, what is manufactured at present with Noni fruit product does not list containing gargling product.
The product of exploitation gargle in the market is to utilize Chlorhexidine and its esters mostly, and Chlorhexidine and its esters are not
Can be edible, containing must be told after gargling, and containing after gargling, Chlorhexidine is easily left a trace on tooth, and not easy-clear, is given people
Health bring hidden danger, also cause very big injury to the attractive in appearance of oral cavity.Therefore, the beautiful gargle ten of promise of exploitation natural health
Divide necessity.The beautiful gargle of promise of natural health is nutritious, containing vitamin, amino acid, mineral matter and many Phytochemistry element,
Inherently one good health drink, it can not only anti-inflammatory, antibacterial, infringement, Er Qieqing are not resulted in the gum of inflammation
Cool, tasty, delicious food.Not only a kind of extremely convenient new promise is provided for people beautiful containing drink is gargled, be also valuable promise Buddhist nun money
Source comprehensive utilization opens new approach, is the product of popular one great market competitiveness of healthy offer.Close at present
In this kind of product, there is not been reported, is worth carrying out research promotion.
The content of the invention
It is an object of the invention to provide a kind of nutrition anti-inflammatory gargle, solving existing gargle can not eat, Er Qiehan
The vestige that rear medicine leaves not easy-clear on tooth is gargled, the problem of causing very major injury to oral cavity attractive in appearance.
It is a further object of the present invention to provide the preparation method of above-mentioned nutrition anti-inflammatory gargle.
The technical solution adopted in the present invention is, a kind of nutrition anti-inflammatory gargle, according to mass percent by following components
Composition：90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5% dipotassium glycyrrhizinate, 3%~5%
Sorbierite, 0.008%~0.01% potassium sorbate, appropriate saleratus, surplus is pure water, and gross mass is 100%.
Another technical scheme of the present invention is, a kind of preparation method of above-mentioned nutrition anti-inflammatory gargle, according to
Following steps are implemented：
Step 1, Noni fruit extract solution is prepared；
Step 2, mix, filter, sterilize
Each component is weighed in mass ratio：
90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5% dipotassium glycyrrhizinate, 3%~
5% sorbierite, 0.008%~0.01% potassium sorbate, add appropriate saleratus after being sufficiently mixed so that the pH value of mixed liquor
To 5.5, finally plus pure water is to gross mass to 100%；Filtering, 100 DEG C of filtrate is sterilized 20 minutes~30 minutes, get Nuo Li nutrition
Anti-inflammatory gargle,.
The beneficial effects of the invention are as follows nutrition anti-inflammatory gargle selection Noni fruit extract solution, menthol, glycyrrhizic acid two
Potassium, sorbierite, potassium sorbate etc. are raw material, are mixed according to a certain percentage, and filling, sterilization is made.It is beautiful certainly first with promise
The endogenous enzymes hydrolysis extraction of body, then extracted part is not extracted in Noni fruit using external enzyme and ethanol, so may be used
It can be extracted water-soluble with fat-soluble active ingredient.Ethanol uses edible ethanol, and mixed liquor is adjusted using saleratus
PH deacidifications, saleratus is a kind of food additives, meets healthy requirement.The nutrition anti-inflammatory gargle has anti-inflammatory, killed
Bacterium, preventing decayed tooth, but nutrition is tasty, is a kind of natural, gargle of hygiene and health.
Embodiment
With reference to embodiment, the present invention is described in detail.
The nutrition anti-inflammatory gargle of the present invention, it is composed of the following components according to mass percent：90% Noni fruit extract solution,
0.005%~0.008% menthol (being used as freshener), 1.2%~1.5% dipotassium glycyrrhizinate (as bacteriostatic agent), 3%~
5% sorbierite (being used as flavor enhancement), 0.008%~0.01% potassium sorbate (as preservative), appropriate saleratus, surplus is
Pure water, gross mass is 100%.
The nutrition anti-inflammatory gargle preparation method of the present invention, implements according to following steps：
Step 1, Noni fruit extract solution is prepared
1.1) by the fresh Noni fruit of maturity seven to eighty per cant, with 1.0mg/L soak with ozone solution 20~30 minutes, washing
Twice, it is filtered dry, is put into closed tank, after normal temperature spontaneous fermentation 10~15 days, smash to pieces, separates, obtain the beautiful extraction of water-soluble promise
Liquid and Noni fruit slag；
1.2) by Noni fruit slag derived above through smashing to pieces, on the basis of Noni fruit slag amount, plus 8~water of 10 times of quality
Mixing, then 0.1% pectase, 0.02% lipase, 0.04% acid protease are separately added into, ordinary-temp hydrolysis 5-7 is small
When, 90 DEG C of enzymes that go out, separation obtains enzymolysis liquid and recrement；
1.3) by the beautiful recrement of the promise 1.2) obtained (recrement includes many hard fruits), drain, smash, according to 1：6
~8 mass ratio is mixed with 50~70% edible ethanol, is soaked 24 hours~36 hours, filtering, and filtrate is in 80 ± 5 DEG C of backflows
Extract, be concentrated in vacuo and reclaim ethanol；Extract repeatedly twice, reclaim ethanol, merging filtrate obtains concentrate；
1.4) merge the above-mentioned beautiful extract of water-soluble promise, enzymolysis liquid and concentrate, the Noni fruit that concentration is 1g/mL is made
Extract solution.
Step 2, mix, filter, sterilize
Each component is weighed in mass ratio：
90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5% dipotassium glycyrrhizinate, 3%~
5% sorbierite, 0.008%~0.01% potassium sorbate, add appropriate saleratus after being sufficiently mixed so that the pH value of mixed liquor
To 5.5, finally plus pure water is to gross mass to 100%；Filtering, 100 DEG C of filtrate is sterilized 20 minutes~30 minutes, get Nuo Li nutrition
Anti-inflammatory gargle,.
Embodiment 1
Step 1, Noni fruit extract solution is prepared
1.1) by the fresh Noni fruit of maturity seven to eighty per cant, with 1.0mg/L soak with ozone solution 20 minutes, washing two
It is secondary, it is filtered dry, is put into closed tank, after normal temperature spontaneous fermentation 10 days, smash to pieces, separates, obtain the beautiful extract of water-soluble promise and promise
Beautiful pomace；
1.2) by Noni fruit slag derived above through smashing to pieces, on the basis of Noni fruit slag amount, plus the water of 8 times of quality is mixed
Close, then be separately added into 0.1% pectase, 0.02% lipase, 0.04% acid protease, ordinary-temp hydrolysis 5 hours, 90
DEG C go out enzyme, separation, obtains enzymolysis liquid and recrement；
1.3) by the beautiful recrement of the promise 1.2) obtained (being much hard fruit), drain, smash, according to 1：6 mass ratio
Edible ethanol with 50% is mixed, and is soaked 24 hours, and filtering, filtrate is concentrated in vacuo in 80 ± 5 DEG C of refluxing extractions and reclaims second
Alcohol；Extract repeatedly twice, reclaim ethanol, merging filtrate obtains concentrate；
1.4) merge the above-mentioned beautiful extract of water-soluble promise, enzymolysis liquid and concentrate, the Noni fruit that concentration is 1g/mL is made
Extract solution.
Step 2, mix, filter, sterilize
Each component is weighed in mass ratio：
90% Noni fruit extract solution is separately added into 0.005% menthol, 1.2% dipotassium glycyrrhizinate, 3% sorbierite,
0.008% potassium sorbate, is mixed, and is added appropriate saleratus and is adjusted pH of mixed to 5.5, finally adds pure water extremely
100%, filtering, 100 DEG C of filtrate is sterilized 20 minutes, produces the beautiful nutrition anti-inflammatory gargle of promise.
Embodiment 2
Step 1, Noni fruit extract solution is prepared
1.1) by the fresh Noni fruit of maturity seven to eighty per cant, with 1.0mg/L soak with ozone solution 20~30 minutes, washing
Twice, be filtered dry, be put into closed tank, after normal temperature spontaneous fermentation 12 days, smash to pieces, separate, obtain the beautiful extract of water-soluble promise with
Noni fruit slag；
1.2) by Noni fruit slag derived above through smashing to pieces, on the basis of Noni fruit slag amount, plus the water of 9 times of quality is mixed
Close, then be separately added into 0.1% pectase, 0.02% lipase, 0.04% acid protease, ordinary-temp hydrolysis 6 hours, 90
DEG C go out enzyme, separation, obtains enzymolysis liquid and recrement；
1.3) by the beautiful recrement of the promise 1.2) obtained (being much hard fruit), drain, smash, according to 1：7 mass ratio
Edible ethanol with 60% is mixed, and is soaked 30 hours, and filtering, filtrate is concentrated in vacuo in 80 ± 5 DEG C of refluxing extractions and reclaims second
Alcohol；Extract repeatedly twice, reclaim ethanol, merging filtrate obtains concentrate；
1.4) merge the above-mentioned beautiful extract of water-soluble promise, enzymolysis liquid and concentrate, the Noni fruit that concentration is 1g/mL is made
Extract solution.
Step 2, mix, filter, sterilize
Each component is weighed in mass ratio：
90% Noni fruit extract solution is separately added into 0.006% menthol, 1.3% dipotassium glycyrrhizinate, 4% sorbierite,
0.009% potassium sorbate, is mixed, and is added appropriate saleratus and is adjusted pH of mixed to 5.5, finally adds pure water extremely
100%, filter, the sterilization 25 minutes of 100 DEG C of filtrate, just get Nuo Li nutrition anti-inflammatory gargle.
Embodiment 3
Step 1, Noni fruit extract solution is prepared
1.1) by the fresh Noni fruit of maturity seven to eighty per cant, with 1.0mg/L soak with ozone solution 20~30 minutes, washing
Twice, be filtered dry, be put into closed tank, after normal temperature spontaneous fermentation 15 days, smash to pieces, separate, obtain the beautiful extract of water-soluble promise with
Noni fruit slag；
1.2) by Noni fruit slag derived above through smashing to pieces, on the basis of Noni fruit slag amount, plus the water of 10 times of quality is mixed
Close, then be separately added into 0.1% pectase, 0.02% lipase, 0.04% acid protease, ordinary-temp hydrolysis 7 hours, 90
DEG C go out enzyme, separation, obtains enzymolysis liquid and drains recrement；
1.3) Nuo Li 1.2) obtained is drained into recrement according to 1：8 mass ratio is mixed with 70% edible ethanol, immersion
36 hours, filtering, filtrate was concentrated in vacuo in 80 ± 5 DEG C of refluxing extractions and reclaims ethanol；Extract repeatedly twice, reclaim ethanol, close
And filtrate, obtain concentrate；
1.4) merge the above-mentioned beautiful extract of water-soluble promise, enzymolysis liquid and concentrate, the Noni fruit that concentration is 1g/mL is made
Extract solution.
Step 2, mix, filter, sterilize
Each component is weighed in mass ratio：
90% Noni fruit extract solution is separately added into 0.008% menthol, 1.5% dipotassium glycyrrhizinate, 5% sorbierite,
0.01% potassium sorbate, is mixed, and is added appropriate saleratus and is adjusted pH of mixed to 5.5, finally adds pure water extremely
100%, filter, the sterilization 30 minutes of 100 DEG C of filtrate, just get Nuo Li nutrition anti-inflammatory gargle.
Claims (1)
1. a kind of preparation method of nutrition anti-inflammatory gargle, the nutrition anti-inflammatory gargle is according to mass percent by following components group
Into：90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5% dipotassium glycyrrhizinate, 3%~5% mountain
Pears alcohol, 0.008%~0.01% potassium sorbate, appropriate saleratus, surplus is pure water, and gross mass is 100%,
Characterized in that, this method is implemented according to following steps：
Step 1, Noni fruit extract solution is prepared：
1.1) by the fresh Noni fruit of maturity seven to eighty per cant, with 1.0mg/L soak with ozone solution 20~30 minutes, washing two
It is secondary, it is filtered dry, is put into closed tank, after normal temperature spontaneous fermentation 10~15 days, smash to pieces, separates, obtain the beautiful extract of water-soluble promise
With Noni fruit slag；
1.2) by Noni fruit slag derived above through smashing to pieces, on the basis of Noni fruit slag amount, plus 8~water of 10 times of quality mixes
Close, then be separately added into 0.1% pectase, 0.02% lipase, 0.04% acid protease, ordinary-temp hydrolysis 5-7 hours,
90 DEG C of enzymes that go out, separation, obtain enzymolysis liquid and recrement；
1.3) by the beautiful recrement of the promise 1.2) obtained, drain, smash, according to 1：6~8 mass ratio and 50~70% edible ethanol
Mixing, soaks 24 hours~36 hours, and filtering, filtrate is concentrated in vacuo at 80 ± 5 DEG C and reclaims ethanol；Extract twice, return repeatedly
Ethanol is received, merging filtrate obtains concentrate；
1.4) merge the above-mentioned beautiful extract of water-soluble promise, enzymolysis liquid and concentrate, concentration is made and is extracted for 1g/mL Noni fruit
Liquid；
Step 2, mix, filter, sterilize：
Each component is weighed in mass ratio：90% Noni fruit extract solution, 0.005%~0.008% menthol, 1.2%~1.5%
Dipotassium glycyrrhizinate, 3%~5% sorbierite, 0.008%~0.01% potassium sorbate；Appropriate saleratus is added after being sufficiently mixed,
So that the pH value of mixed liquor is to 5.5, finally plus pure water is to gross mass to 100%；Filtering, the sterilization 20 minutes of 100 DEG C of filtrate~
30 minutes, get Nuo Li nutrition anti-inflammatory gargles,.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796428A (en) * | 2016-04-20 | 2016-07-27 | 苏州蔻美新材料有限公司 | Medical tooth sanitary cleanser and preparation method thereof |
| CN106924120A (en) * | 2017-04-25 | 2017-07-07 | 上海中翊日化有限公司 | A kind of oral care substance of antibacterial, fresh breath |
| CN107157837A (en) * | 2017-06-01 | 2017-09-15 | 南京辅安堂药业有限公司 | A kind of black tea gargle and preparation method thereof |
| CN112386538A (en) * | 2020-11-19 | 2021-02-23 | 广东轻工职业技术学院 | Noni mouthwash and preparation process thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1859852A (en) * | 2003-09-26 | 2006-11-08 | 诺丽公司 | Morinda citrifolia-based oral care compositions and methods |
| CN102703217A (en) * | 2012-06-04 | 2012-10-03 | 云南烟草科学研究院 | Noni extract and application thereof |
| CN102940290A (en) * | 2012-11-27 | 2013-02-27 | 俞丹 | Method for preparing Noni juice |
| CN104258092A (en) * | 2014-10-24 | 2015-01-07 | 王志敏 | Gargle for treating recurrent aphthous ulcer and periodontitis and preparation method thereof |
-
2015
- 2015-04-21 CN CN201510191675.3A patent/CN104758216B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1859852A (en) * | 2003-09-26 | 2006-11-08 | 诺丽公司 | Morinda citrifolia-based oral care compositions and methods |
| CN102703217A (en) * | 2012-06-04 | 2012-10-03 | 云南烟草科学研究院 | Noni extract and application thereof |
| CN102940290A (en) * | 2012-11-27 | 2013-02-27 | 俞丹 | Method for preparing Noni juice |
| CN104258092A (en) * | 2014-10-24 | 2015-01-07 | 王志敏 | Gargle for treating recurrent aphthous ulcer and periodontitis and preparation method thereof |
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Inventor after: Yi Meihua Inventor after: Huang Yefu Inventor after: Mao Xiangfei Inventor after: Liu Aisha Inventor after: Teng Fei Inventor before: Tan Wangqiao Inventor before: Yi Meihua Inventor before: Mao Xiangfei Inventor before: Liu Aisha Inventor before: Teng Fei |
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