CN104740179A - Traditional Chinese medicine composition for treating obstruction of central rentinal artery - Google Patents
Traditional Chinese medicine composition for treating obstruction of central rentinal artery Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating obstruction of central rentinal artery. The traditional Chinese medicine composition is prepared from the following raw material medicines: 20g of astragalus, 15g of white atractylodes rhizome, 12g of radix glycyrrhizae, 20g of radix angelicae sinensis, 12g of motherwort fruit, 15g of earthworms, 6g of ligusticum wallichii, 15g of prepared rehmannia root, 10g of schisandra chinensis, 15g of wolfberries, 15g of radix bupleuri, 12g of rhizoma cyperi, 10g of rhizoma corydalis, 12g of scutellaria baicalensis, 15g of radix gentianae, 12g of selfheal, 12g of chrysanthemum flowers. The prescription is modified according to the syndrome differentiation as follows: for headache and dizziness, 12g of gastrodia elata and 10g of uncaria are added to calm liver wind; for severe retinal edema, 12g of poria cocos, 12g of rhizoma alismatis and 10g of leonurus are added to promote xeransis and dieresis; for greasy fur and slippery pulses, 10g of stiff silkworms, 12g of pinellia ternate and 10g of arisaema cum bile are added to remove dampness to reduce phlegm; and for poor sleep, 15g of wild jujube seeds and 12g of platycladi seeds are added to tranquilize mind by nourishing the heart. The traditional Chinese medicine composition is prepared from pure traditional Chinese medicines, and small in toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, belong to technical field of Chinese medicines.
Background technology
Central retinal artery occlusion is because the reasons such as vasospasm, thrombosis and outside compressing cause retinochrome blood for being obstructed, and causes amphiblestroid acute ischemia, vision degradation.Central retinal artery occlusion causes one of emergency case blind suddenly, because the reasons such as arteriospasm, embolic infarction, endarteritis or atherosclerosis cause.Treat available vasodilation medicine and carry out emergency treatment, suck amyl nitrite or sublingual administration nitroglycerin immediately.Can application of fiber solubility preparation to being suspected to have the patient that thrombosis or Fibrinogen increase.Intravenous drip or slowly inject urokinase; Or use defibrase intravenous drip.Also can the PID such as oral aspirin, dipyridamole and blood-activating and stasis-removing.These Western medicine majorities are clinical emergency treatment medicine, take effect than comparatively fast, but it are cured the symptoms, not the disease, and does not fundamentally improve amphiblestroid blood circulation situation.The traditional Chinese medical science, by activating blood circulation to dissipate blood stasis, is improved Microcirculation for Treatment central retinal artery occlusion, is achieved certain effect, obtains vast central retinal artery occlusion patient accreditation.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of central retinal artery occlusion.
The object of the invention is to be realized by following scheme: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams.Dialectical plus-minus: headache and dizzy person adds 12 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams, with suppressing the hyperactive liver to relieve the wind syndrome; Retinal edema seriously adds 12 grams, Poria, Rhizoma Alismatis 12 grams, Herba Leonuri 10 grams, with eliminating dampness and promoting diuresis; Greasy fur rolling pulse person, adds Bombyx Batryticatus 10 grams, the Rhizoma Pinelliae 12 grams, Arisaema Cum Bile 10 grams with drying dampness to eliminate phlegm.Poor sleep adds Semen Ziziphi Spinosae 15 grams, Semen Platycladi 12 grams with tranquilizing by nourishing the heart.
Using method: be decocted in water for oral dose, every day potion, point early, evening takes for twice, 10 days courses for the treatment of.
The traditional Chinese medical science thinks that primary disease is many because of emotional maladjustment, qi depression to blood stasis; Or the deficiency of vital energy is not enough, promoting the circulation of blood is unable, stagnation of QI-blood; Or surfeit delicious food, dysfunction of the spleen in transportation, Phlegm to hinder collaterals; Or hyperactivity of YANG due to deficiency of YIN, dynamic in liver-fire, above disturb key clearly, upward invasion of liver-QI, closing venation etc., all can make qi-blood disharmony, ophthalmic blood network stasis blocking, malnutrition of eyes and send out primary disease.Treatment is with benefiting QI for activating blood circulation, and YIN nourishing nourishing the liver, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling is main.Determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs: headache and dizzy person, hot-tempered guerulent mostly is liver-wind stirring up internally; Obesity, greasy fur rolling pulse person is Phlegm to hinder collaterals; Edema is seriously that damp and hot mistake is contained.
In formula of the present invention, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae invigorating the spleen and replenishing QI; Radix Angelicae Sinensis, Fructus Leonuri, Pheretima, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling; Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Fructus Lycii Yin-nourishing and body fluid promoting, nourishing the liver to improve visual acuity; Radix Bupleuri, Rhizoma Cyperi, Rhizoma Corydalis depressed liver-energy dispersing and QI regulating; Radix Scutellariae, Radix Gentianae, Spica Prunellae, Flos Chrysanthemi heat-clearing and toxic substances removing.Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis suppressing the hyperactive liver to relieve the wind syndrome; Poria, Rhizoma Alismatis, Herba Leonuri eliminating dampness and promoting diuresis; Bombyx Batryticatus, the Rhizoma Pinelliae, Arisaema Cum Bile drying dampness to eliminate phlegm; Semen Ziziphi Spinosae, Semen Platycladi tranquilizing by nourishing the heart.Above-mentioned all medicine compatibilities play effect of benefiting QI for activating blood circulation, nourishing kidney yin, promoting blood circulation to remove obstruction in the collateral, clearing away heat and relieving the wind syndrome, suppressing the hyperactive liver improving eyesight altogether.Treat in conjunction with disease is dialectical, treatment central retinal artery occlusion is played to the effect for the treatment of both the principal and secondary aspects of a disease.
The pure Chinese medicine of the present invention is produced, and toxic and side effects is little.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams.
Embodiment 2: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, 12 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams.
Embodiment 3: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, 12 grams, Poria, Rhizoma Alismatis 12 grams, Herba Leonuri 10 grams.
Embodiment 4: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, Bombyx Batryticatus 10 grams, the Rhizoma Pinelliae 12 grams, Arisaema Cum Bile 10 grams.
Embodiment 5: a kind of Chinese medicine composition for the treatment of central retinal artery occlusion, is made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, Semen Ziziphi Spinosae 15 grams, Semen Platycladi 12 grams.
Clinical data
1, basic document.
My institute accepts central retinal artery occlusion patient 46 example year January in January, 2013 to 2014 for medical treatment, all adopts Chinese medicine of the present invention to carry out Ureteral Calculus.Wherein man 32 example, female 14 example; Minimum 36 years old of age, maximum 71 years old, average 56 years old; Right eye 26 example, left eye 20 example; The shortest person of the course of disease 2 hours, most elder 24 hours.Check finding: vision is all faint.Platycoria, direct light reflex weakens or disappears, and consensual reflex exists, the greyish white muddy edema of retina, macular area cherry red spot.2 Therapeutic Method.Necessary first carries out emergency treatment with vasodilation medicine, then to Chinese medicine of the present invention, is decocted in water for oral dose, every day potion.All at treatment observing effect after 20 days.3 observation of curative effect 3.1 criterions of therapeutical effect are cured as vision >=1.0, and optical fundus blood vessel recovers normal; Effective is vision raising >=3 row, and optical fundus blood vessel recovers to some extent; Transfer well vision to and improve 1 ~ 2 row, optical fundus blood vessel has recovery: invalid is that vision is unchanged.3.2 therapeutic outcomes, through the treatment of 2 courses for the treatment of, cure 31 examples, effective 9 examples, and effective 6 examples, total effective rate is 100%.
Model case
Case 1: patient Zhang, man, 63 years old, goes to a doctor on October 20th, 2013 to my institute's ophthalmology.Main suit: the unexpected blurred vision of right eye, constriction of visual field.Ophthalmologic examination: vision: right eye 0.3, left eye 1.0.Right eye direct light reflex is blunt, and consensual reflex is normal, and binocular lense is transparent, and vitreous body is without muddiness.Examination of ocular fundus: right eye pallor papillae, Zinn's artery attenuates, and nipple temporo side-looking nethike embrane kermesinus, peripheral retinal tear is canescence edema, and left examination of ocular fundus is normal.Diagnosis: retina of right eye central artery blocks.First carry out emergency treatment with vasodilation medicine, to Chinese medicine of the present invention, be decocted in water for oral dose, every day potion, after taking 10 days, right eye perspective recovers normal, and vision brings up to 0.6 by 0.3, continual cure 10 days vision right eyes return to 1.0, and retinal edema disappears, and optical fundus blood vessel recovers the normal flow direction.
Case 2: patient Bai, female, 53 years old, on June 22nd, 2013, right eye is blind was suddenly in hospital.Ophthalmologic examination: left vision: no light perception, right vision: 1.0.Cornea of left eye platycoria, disappears to luminous reflectance.Right eye is normal.Examination of ocular fundus: retina of left eye canescence edema, Zinn's artery obviously attenuates, and macular area is Fructus Pruni pseudocerasi erythema.Right eye is normal.Blood pressure 165/100mmhg.Diagnosis: retina of left eye central artery blocks.First carry out emergency treatment with vasodilation medicine, then give Chinese medicine of the present invention, be decocted in water for oral dose, every day potion, take antihypertensive drugs simultaneously, after taking 10 days, left vision recovers to some extent, and sight line is slightly fuzzy, eyesight testing 0.4, continual cure 20 days vision restorations are to 1.0, and retina is red and swollen, speckle disappears, and recovery from illness is left hospital.Pay a return visit without recurrence.
Case 3: patient field so-and-so, female, 48 years old, on May 6th, 2013 because of the unexpected blurred vision of left eye, the visual field diminish come institute treatment.Ophthalmologic examination: left vision 0.2, right eye 1.0, examination of ocular fundus: retina of left eye nipple is pale, edema obscurity boundary is unclear, central artery attenuates, nipple temporo side-looking nethike embrane kermesinus, and foveal reflex disappears, its peripheral retinal tear is canescence edema, and right examination of ocular fundus is normal, has hypertension history.Be diagnosed as retina of left eye central artery to block.To Chinese medicine of the present invention, be decocted in water for oral dose, every day, potion, took antihypertensive drugs simultaneously, and after taking 10 days continuously, left vision brings up to 0.5, and continual cure 10 days left visions return to 0.8, and the infiltration of view edema is controlled.
Claims (5)
1. treat the Chinese medicine composition of central retinal artery occlusion for one kind, it is characterized in that, be made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams.
2. treat the Chinese medicine composition of central retinal artery occlusion for one kind, it is characterized in that, be made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, 12 grams, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis 10 grams.
3. treat the Chinese medicine composition of central retinal artery occlusion for one kind, it is characterized in that, be made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, 12 grams, Poria, Rhizoma Alismatis 12 grams, Herba Leonuri 10 grams.
4. treat the Chinese medicine composition of central retinal artery occlusion for one kind, it is characterized in that, be made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, Bombyx Batryticatus 10 grams, the Rhizoma Pinelliae 12 grams, Arisaema Cum Bile 10 grams.
5. treat the Chinese medicine composition of central retinal artery occlusion for one kind, it is characterized in that, be made up of following crude drug: the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 12 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 grams, Fructus Leonuri 12 grams, Pheretima 15 grams, Rhizoma Chuanxiong 6 grams, Radix Rehmanniae Preparata 15 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Lycii 15 grams, Radix Bupleuri 15 grams, Rhizoma Cyperi 12 grams, Rhizoma Corydalis 10 grams, Radix Scutellariae 12 grams, Radix Gentianae 15 grams, Spica Prunellae 12 grams, Flos Chrysanthemi 12 grams, Semen Ziziphi Spinosae 15 grams, Semen Platycladi 12 grams.
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| 张祖海: "中医辨证论治视网膜中央动脉阻塞55例疗效观察", 《中国现代医生》 * |
| 张铭连等: "活血通络治疗视网膜动脉阻塞61例", 《辽宁中医杂志》 * |
| 陈燕: "葛根素注射液联合血府逐瘀汤治疗视网膜中央动脉阻塞30例临床观察", 《中国中医急症》 * |
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