CN104771638A - Traditional Chinese medicine composition for treating optic atrophy - Google Patents

Traditional Chinese medicine composition for treating optic atrophy Download PDF

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Publication number
CN104771638A
CN104771638A CN201510195513.7A CN201510195513A CN104771638A CN 104771638 A CN104771638 A CN 104771638A CN 201510195513 A CN201510195513 A CN 201510195513A CN 104771638 A CN104771638 A CN 104771638A
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chinese medicine
medicine composition
traditional chinese
blood
optic atrophy
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潘伟
钱立伟
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Abstract

The invention relates to a traditional Chinese medicine composition for treating optic atrophy. The traditional Chinese medicine composition consists of the following traditional Chinese medicine raw materials by weight: 10-20g of millet, 5-15g of leaf of oval kumquat, 5-10g of white backleaf mallotus root, 3-7g of root of snow of june, 5-10g of rose, 3-5g of style and stigma of saffron crocus, 3-8g of abrus herb, 5-15g of parslane herb, 2-5g of sensitiveplat root, 3-7g of Japanese polypody rhizome, 5-8g of herb of frail horsetail, 5-10g of perilla stem and 4-8g of stem of Chinese starjasmine. The traditional Chinese medicine composition provided by the invention has the effects of nourishing yin and tonifying kidney, soothing the liver and relieving depression, benefiting qi and nourishing blood, dredging collaterals to improve eyesight, as well as regulating qi and invigorating the blood, is used for treating the optic atrophy based on syndrome differentiation, is significant in curative effect and high in effective rate and does not have toxic and side effects.

Description

Be used for the treatment of the Chinese medicine composition of optic atrophy
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition being used for the treatment of optic atrophy.
Background technology
Optic atrophy is not the title of a disease, and refer to that any disease causes retinal ganglial cells and its aixs cylinder generation pathological changes, the one causing optic nerve all to attenuate is formed to learn and changes, for the noun that pathology are general, generally betide the Ganglion cell axon degeneration between retina to lateral geniculate body.Its cause of disease, generally speaking, child's optic atrophy is with more caused by brain tumor or intracranial inflammation; Adolescent patients is based on heritability; Aged patients mostly then is optic neuritis or neurotrauma; Old people Ze Chang is relevant with glaucoma or the vascular cause of disease.
Main manifestations visual deterioration and optic disc are canescence or pale.Can occur crack shape or wedge-shaped defect during optic disc peripheral nerve fibrous layer disease damage, the former becomes comparatively black, for layer of retina,pigmentary exposes; The latter, in more red, is choroid exposure.If infringement betides lower edge district on optic disc, then more easy to identify, because this district's nerve fibre layer thickens especially, if disease damage is away from optic disc district, because these regional nerve Conductivity of Fibers are thinning, then not easily find.Often point out nerve fibre layer to have pathological changes with focal atrophy around optic disc, be nerve fibre layer thinning in this district caused by.
Optic atrophy belongs to " optic atrohic blindness " category in Chinese medicine.The cause of disease comprises that to injure natural endowment outside diseases caused by exogenous pathogenic factor six climate exopathogens, seven emotions pent-up, eating and drinking without temperance, work and rest mistake degree, calentura prolonged illness, the head not enough etc.Its pathogenesis is as follows:
Suffer from a deficiency of the kidney: or because of natural endowment not enough, or because of high thermal burn cloudy, or because of prolonged illness overstrain, cause deficiency of kidney-YIN, asthenia of essence and blood, the kidney failing to nourish the liver, hyperactivity of deficient fire, impairment of body fluid consumption liquid, essence and blood can not sending nutrient upward to eye and cause optic atrohic blindness.
Liver is evil: how because feelings will is unsuccessful, angry impairing the liver, depression of liver-QI, catharsis is neglected one's duty, functional activity of QI being not smooth, and blood with the stagnation of QI, or is sent out because other reasons causes mechanism of qi to rise, and catharsis function mistakes degree, also can cause depression of liver-QI, and the retardance of order network, body fluid is not all right, can not moisten to support to fall ill in order.
Deficiency of qi and blood: how because of natural endowment deficiency, or eating and drinking without temperance, overwork, weakness of the spleen and stomach, and the biochemical weary source of QI and blood, runs unable.The deficiency of vital energy is blurring of vision then, and blood deficiency is loss of nutrient of eyes then, all can cause optic atrohic blindness.
Qi depression to blood stasis: or because of injury of head, order system is impaired, or feelings will is not relaxed, and during pent-up for a long time, or due to pathogen usually intruding into collateral in protracted disease, causes stagnation of blood stasis venation, vital essence can not on reach caused by the order.
That commonly uses in the medicine of current optic atrophy comprises neurotrophy medicine as vitamin B1, B12, ATP and coenzyme A etc., and vasodilator and promoting blood flow and remove blood stasis drug class are as Yan acid, bendazol, vitamin E, troxerutin, compound Salviae Miltiorrhizae etc.Chinese traditional treatment then more adopts acupuncture and moxibustion treatment.
Summary of the invention
The object of the present invention is to provide a kind of evident in efficacy, the Chinese medicine composition of what effective percentage was high be used for the treatment of optic atrophy.
The technical solution adopted for the present invention to solve the technical problems is: the Chinese medicine composition being used for the treatment of optic atrophy, is made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 10-20g, Folium Fortunellae Margarita 5-15g, Radix Malloti Apelitae 5-10g, Radix Serissae 3-7g, Flos Rosae Rugosae 5-10g, Stigma Croci 3-5g, Herba Abri 3-8g, Herba Portulacae 5-15g, Radix Mimosae Pudicae 2-5g, Rhizoma Polypodiodis Nipponicae 3-7g, Herba Clinopodii Polycephali 5-8g, Caulis Perillae 5-10g, Caulis Trachelospermi 4-8g.
Preferably, be used for the treatment of the Chinese medicine composition of optic atrophy, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 15g, Folium Fortunellae Margarita 10g, Radix Malloti Apelitae 10g, Radix Serissae 5g, Flos Rosae Rugosae 5g, Stigma Croci 4g, Herba Abri 5g, Herba Portulacae 10g, Radix Mimosae Pudicae 4g, Rhizoma Polypodiodis Nipponicae 5g, Herba Clinopodii Polycephali 5g, Caulis Perillae 8g, Caulis Trachelospermi 4g.
The pharmacologically active of the present invention's raw material of Chinese medicine is as follows:
Semen setariae is the kernel of grass foxtail millet, and sweet in the mouth is salty, cool in nature, returns kidney, spleen, stomach warp, and middle kidney tonifying; Heat extraction; Removing toxic substances.Main taste deficiency-heat; Regurgitation is vomitted; Abdominal distention lack of appetite; Quench one's thirst; Dysentery; Burn and scald." the southern regions of the Yunnan Province book on Chinese herbal medicine ": main YIN nourishing, supports kidney qi, strengthening the spleen and stomach, in warm.Control regurgitation, Pediatric Liver worm, or cholera is vomited and diarrhoea, tripe pain dysentery, watery diarrhea is more than.
Folium Fortunellae Margarita is the leaf of Rutaceae plant Fructus Fortunellae Margaritae and golden bullet, acrid in the mouth, and bitter, cold nature, returns liver, spleen, lung meridian, soothing liver-QI for relieving depression; To regulate the flow of vital energy eliminating stagnation.Main dysphagic; Scrofula; Breast lumps; Mastitis.
Radix Malloti Apelitae is the root of the white Chinese catalpa of Radix Euphorbiae Pekinensis kind of plant, mildly bitter flavor; Puckery; Property is put down, and returns spleen, kidney, urinary bladder channel, heat clearing away; Damp eliminating; Astringent therapy; Repercussive.Main hepatitis intestinal is scorching; Stranguria with turbid discharge; Leukorrhagia; Proctoptosis; Uterine prolapse; Hepatosplenomegaly; Osteopatia sprain.This product has soothing liver-QI for relieving depression, the effect of blood circulation promoting and blood stasis dispelling.
Radix Serissae is the herb of Maguireothamnus speciosus Radix Serissae or Serissa foetida, and toil is cool, returns liver, spleen channel, dispels the wind; Dampness removing; Heat clearing away; Removing toxic substances.Main flu; Icterohepatitis; Oedema due to nephritis; Cough; Laryngalgia; Keratitis; Intestinal is scorching; Dysentery; Lumbago and skelalgia; Hemoptysis; Hematuria; Women's amenorrhea; Leucorrhea; Infantile malnutrition; Infantile convulsion; Acute toothache; Swollen ulcer drug; Traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook ": " soothing liver-QI for relieving depression, clearing away heat-damp and promoting diuresis, detumescence and drawing out poison.Control acute hepatitis, chronic hepatitis, lumbago, skelalgia of rheumatism, carbuncle malignant boil, snakebite.″
Flos Rosae Rugosae is the flower of rosaceous plant Flos Rosae Rugosae and polyphyll Flos Rosae Rugosae, and sweet, micro-hardship, temperature, returns liver, spleen channel, resolving depression of regulating the flow of vital energy, and blood dissipating blood stasis.Treating the liver peratodynia, new lingering pathogenic wind numbness, spitting of blood of spitting blood, menoxenia, leucorrhea with red and white discharge, dysentery, acute mastitis, toxic swelling.Supplementary Amplifications of the Compendium of Materia Medica: and blood, promoting the circulation of blood, regulates the flow of vital energy.Control migratory arthralgia.
Stigma Croci, this product is the dry stigma of Iridaceae crocus plant Stigma Croci, sweet, flat, GUIXIN, Liver Channel, blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization.For amenorrhea lump in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.
Herba Abri is the whole herb with root of leguminous plant Guangdong Semen Abri Precatorii, sweet, bitter; Cool, GUIXIN, lung, liver, stomach, kidney channel, heat-clearing and toxic substances removing, soothing liver-QI dissipating blood stasis.Main icterohepatitis, stomachache, rheumatic ostalgia, traumatic injury stasis of blood pain, mastalgia.
Herba Portulacae is the herb of portulacaceous plant Herba Portulacae, acid, cold in nature, returns large intestine, Liver Channel, heat-clearing and toxic substances removing, cooling blood for hemostasis.For toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis." detailed outline ": " loose blood detumescence, sharp intestinal habitual abortion, detoxifies treating stranguria, sweating due to debility after managing property.″
Radix Mimosae Pudicae is the root of leguminous plant Herba Mimosae Pudicae, puckery, and micro-hardship is warm in nature, relieving cough and resolving phlegm; Dampness removing dredging collateral; Stomach function regulating removing food stagnancy; Improving eyesight is calm.Main chronic bronchitis; Rheumatalgia; Chronic gastritis; Infantile dyspepsia; Amenorrhea; Headache and insomnia; Dim eyesight." Yunnan Chinese herbal medicine ": dampness removing dredging collateral, improving eyesight, calm.
Rhizoma Polypodiodis Nipponicae is the rhizome of Plants of Polypodiaceae Rhizoma Polypodiodis Nipponicae, bitter, cool, GUIXIN, liver, lung meridian, clearing away heat-damp and promoting diuresis; Promoting blood circulation to remove obstruction in the collateral.Main acute diseases such as cholera and sunstroke stranguria with turbid discharge; Have loose bowels; Rheumatic arthralgia; Traumatic injury." Chinese Herbal Medicine in Xinjiang handbook ": heat-clearing and toxic substances removing, suppressing the hyperactive liver improving eyesight.Control urinary tract infection, enteritis, infantile hyperpyrexia infantile convulsion." Shaanxi Chinese herbal medicine ": promoting flow of QI and blood, detumescence dissipating blood stasis.Control traumatic injury, impairment caused by overstrain, lumbago and skelalgia, hemiplegia, tinea alba.
Herba Clinopodii Polycephali is the herb of Equisetaceae horse-tail Herba Clinopodii Polycephali, sweet, micro-hardship, heat clearing away, diuresis, improving acuity of vision and removing nebula, expelling phlegm for arresting cough.For conjunctival congestion and swelling pain, corneal nebula, hepatitis, cough, bronchitis, urinary system infection.
Caulis Perillae is the stem of labiate Folium Perillae or wild Folium Perillae, and acrid in the mouth is warm in nature, returns spleen, stomach, lung meridian, regulating the flow of QI to ease the stomach; Antiabortive; And blood.Main stagnation of QI in spleen and stomach; Gastral cavity abdomen feeling of fullness, nausea is got along well, edema beriberi, and spitting of blood tells nosebleed." must join book on Chinese herbal medicine ": soothing the liver, sharp lung, regulates the flow of vital energy, and blood, resolving depression, and pain relieving is coughed surely, antiabortive.
Caulis Trachelospermi is stem, the leaf of apocynaceae plant trachelospermum jasminoide, bitter, pungent, cold nature, and GUIXIN, liver, kidney channel, dispel the wind, dredging collateral, hemostasis, repercussive.Dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins, carbuncle, sore throat, spits blood, traumatic injury, disease that postpartum lochia can't go.
Chinese medicine composition of the present invention has effect of nourishing YIN for benefiting the kidney, soothing liver-QI for relieving depression, benefiting qi and nourishing blood, dredging collateral improving eyesight, vital energy regualting and blood circulation-promoting, and to optic atrophy Coryza Treated by Syndrome Differentiation, evident in efficacy, effective percentage is high, has no side effect.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Be used for the treatment of the Chinese medicine composition of optic atrophy, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 10g, Folium Fortunellae Margarita 15g, Radix Malloti Apelitae 6g, Radix Serissae 6g, Flos Rosae Rugosae 6g, Stigma Croci 3g, Herba Abri 6g, Herba Portulacae 5g, Radix Mimosae Pudicae 3g, Rhizoma Polypodiodis Nipponicae 3g, Herba Clinopodii Polycephali 8g, Caulis Perillae 5g, Caulis Trachelospermi 8g.
Embodiment 2
Be used for the treatment of the Chinese medicine composition of optic atrophy, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 15g, Folium Fortunellae Margarita 10g, Radix Malloti Apelitae 10g, Radix Serissae 5g, Flos Rosae Rugosae 5g, Stigma Croci 4g, Herba Abri 5g, Herba Portulacae 10g, Radix Mimosae Pudicae 4g, Rhizoma Polypodiodis Nipponicae 5g, Herba Clinopodii Polycephali 5g, Caulis Perillae 8g, Caulis Trachelospermi 4g.
Embodiment 3
Be used for the treatment of the Chinese medicine composition of optic atrophy, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 20g, Folium Fortunellae Margarita 8g, Radix Malloti Apelitae 8g, Radix Serissae 3g, Flos Rosae Rugosae 10g, Stigma Croci 5g, Herba Abri 3g, Herba Portulacae 15g, Radix Mimosae Pudicae 2g, Rhizoma Polypodiodis Nipponicae 7g, Herba Clinopodii Polycephali 6g, Caulis Perillae 10g, Caulis Trachelospermi 5g.
Embodiment 4
Be used for the treatment of the Chinese medicine composition of optic atrophy, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 18g, Folium Fortunellae Margarita 5g, Radix Malloti Apelitae 5g, Radix Serissae 7g, Flos Rosae Rugosae 9g, Stigma Croci 3g, Herba Abri 8g, Herba Portulacae 13g, Radix Mimosae Pudicae 5g, Rhizoma Polypodiodis Nipponicae 6g, Herba Clinopodii Polycephali 7g, Caulis Perillae 7g, Caulis Trachelospermi 7g.
Clinical practice
Physical data: by traditional Chinese medicine composition for treating optic atrophy 45 example of the present invention, wherein man 21 example, female 24 example.
Therapeutic Method: Chinese medicine composition of the present invention is decocted in water for oral dose, every day potion, one day twice, sooner or later sub-service 20 days was a course for the treatment of.
Curative effect judging standard:
Be almost recovered: transference cure, vision is more than 1.0, and normally, there is certain improvement on optical fundus for the visual field and colour vision.
Effective: symptom is obviously improved, vision increases more than 4 row, and the visual field and colour vision significantly take a turn for the better, but optical fundus is improved not obvious.
Effective: symptom is improved, and vision increases more than 1 row, and the visual field and colour vision have certain improvement, but optical fundus is improved not obvious.
Invalid: before and after treatment, symptom, vision, the visual field, colour vision and optical fundus have no change.
Therapeutic outcome: through the treatment of 2-5 the course for the treatment of, 45 routine patients be almost recovered 21 example, effective 15 example, effective 7 example, invalid 2 example, total effective rate 95.6%.
Model case 1
Grandson, man, 37 years old, eyes, because of wound visual deterioration 2 months, looked into OD light sensation, OS0.2, right eye pallor papillae, and boundary is clear, C/D=1.0, and macula lutea luminous reflectance disappears, and it is in vain light that nipple is looked on a left side, and boundary is clear, and C/D=0.6, retina of both eyes blood vessel attenuates.Eye is without significant discomfort, and tongue limit point blood stasis, petechia, hesitant pulse, is diagnosed as traumatic optic atrophy.With after three courses for the treatment of of traditional Chinese medicine composition for treating of the present invention, vision Vos0.5, Vod0.1, symptom is obviously improved.
Model case 2
Wu so-and-so, female, 53 years old, eyes anti-glaucoma surgery visual deterioration.Have a medical check-up Vod0.08, Vos0.06, tubular visual field, optical fundus pallor papillae, border Sexual Physiology depression expands, C/D=0.9, A/V=1: 3, nethike embrane periphery pigmentation, intraocular pressure OD44mmHg, OS46mmHg, eyes are dry and astringent, have a headache dizzy, insomnia and dreamful sleep, tinnitus and soreness of loins, a small amount of blood stasis point of tongue limit point, few tongue, thready and stringy pulse.Be diagnosed as anti-glaucoma surgery optic atrophy.Alleviate by symptom after two courses for the treatment of of traditional Chinese medicine composition for treating of the present invention, two courses for the treatment of of continual cure, intraocular pressure declines, OD21mmHg, OS23mmHg, and vision improves, OD0.2, OS0.1.

Claims (2)

1. be used for the treatment of the Chinese medicine composition of optic atrophy, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 10-20g, Folium Fortunellae Margarita 5-15g, Radix Malloti Apelitae 5-10g, Radix Serissae 3-7g, Flos Rosae Rugosae 5-10g, Stigma Croci 3-5g, Herba Abri 3-8g, Herba Portulacae 5-15g, Radix Mimosae Pudicae 2-5g, Rhizoma Polypodiodis Nipponicae 3-7g, Herba Clinopodii Polycephali 5-8g, Caulis Perillae 5-10g, Caulis Trachelospermi 4-8g.
2. be used for the treatment of the Chinese medicine composition of optic atrophy as claimed in claim 1, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Semen setariae 15g, Folium Fortunellae Margarita 10g, Radix Malloti Apelitae 10g, Radix Serissae 5g, Flos Rosae Rugosae 5g, Stigma Croci 4g, Herba Abri 5g, Herba Portulacae 10g, Radix Mimosae Pudicae 4g, Rhizoma Polypodiodis Nipponicae 5g, Herba Clinopodii Polycephali 5g, Caulis Perillae 8g, Caulis Trachelospermi 4g.
CN201510195513.7A 2015-04-23 2015-04-23 Traditional Chinese medicine composition for treating optic atrophy Pending CN104771638A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770523A (en) * 2016-03-10 2016-07-20 孙桂霞 Medicinal composition for treating optic atrophy

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770523A (en) * 2016-03-10 2016-07-20 孙桂霞 Medicinal composition for treating optic atrophy

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