CN103830513A - Traditional Chinese medicine preparation for treating primary glaucoma - Google Patents
Traditional Chinese medicine preparation for treating primary glaucoma Download PDFInfo
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- CN103830513A CN103830513A CN201410092088.4A CN201410092088A CN103830513A CN 103830513 A CN103830513 A CN 103830513A CN 201410092088 A CN201410092088 A CN 201410092088A CN 103830513 A CN103830513 A CN 103830513A
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating primary glaucoma, which is prepared from the following raw medicines in parts by weight: 23-27 parts of spica prunellae, 23-27 parts of radix paeoniae alba, 23-27 parts of nacre mother of pearl, 23-27 parts of plantain herb, 18-22 parts of radix bupleuri, 18-22 parts of radix bupleuri, 18-22 parts of cassia seed, 18-22 parts of flos chrysanthemi, 14-16 parts of radix rehmanniae praeparata, 14-16 parts of rhizoma alismatis, 14-16 parts of Chinese angelica, 14-16 parts of earthworm, 14-16 parts of rhizoma cyperi, 14-16 parts of uncaria rhynchophylla, 14-16 parts of rhizoma smilacis glabrae, 14-16 parts of cassia twig, 14-16 parts of platycodon grandiflorum, 14-16 parts of scutellaria baicalensis, 14-16 parts of radix saposhnikoviae, 4-6 parts of rhizoma chuanxiong, 4-6 parts of endothelium corneum gigeriae galli, 4-6 parts of stiff silkworm, 4-6 parts of areca catechu and 4-6 parts of liquoric root. The traditional Chinese medicine preparation provided by the invention has the advantages of good curative effect, high effect taking speed, no toxic or side effect and rare recurrence.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the treatment of primary glaucoma.
Background technology
Glaucoma refers to that intraocular pressure is interrupted or the lasting a kind of oculopathy raising, and lasting high intraocular pressure bring infringement can to eyeball each several part tissue and visual function, causes excavation of optic disc, defect of visual field because intraocular pressure increases, and finally can cause blind serious oculopathy.Normal person's intraocular pressure is 10-21mmHg, and exceeding 24mmHg is pathological phenomenon.Intraocular pressure increases can cause visual function damage, and large and dark depression appears in optic disc, and the visual field visible glaucoma typical case change.It is more of a specified duration that intraocular pressure increases the persistent period, and visual function damage is more serious.The reason that glaucoma intraocular pressure increases is that the dynamic equilibrium of aqueous humor circulation has been subject to destruction.Minority is because secretion of aqueous humor is too much, but most or flow of aqueous humor goes out to have occurred obstacle, even closes, trabecular sclerosis etc. as angle of anterior chamber is narrow.As treatment not in time, the visual field can total loss and arrive blind.Glaucoma can be divided into primary glaucoma, secondary glaucoma and congenital glaucoma three types.
At present, the medicine for the treatment of primary glaucoma is few, and has the deficiencies such as curative effect is not obvious, toxic and side effects large, easy recurrence.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of Chinese medicine preparation for the treatment of primary glaucoma, the present invention has advantages of good effect, instant effect, has no side effect, is difficult for recurrence.
A kind of Chinese medicine preparation for the treatment of primary glaucoma, crude drug by following weight portion is made: Spica Prunellae 23-27 part, Radix Paeoniae Alba 23-27 part, Concha Margaritifera 23-27 part, Herba Plantaginis 23-27 part, Radix Bupleuri 18-22 part, Radix Puerariae 18-22 part, Semen Cassiae 18-22 part, Flos Chrysanthemi 18-22 part, Radix Rehmanniae Preparata 14-16 part, Rhizoma Alismatis 14-16 part, Radix Angelicae Sinensis 14-16 part, Pheretima 14-16 part, Rhizoma Cyperi 14-16 part, Ramulus Uncariae Cum Uncis 14-16 part, Rhizoma Smilacis Glabrae 14-16 part, Ramulus Cinnamomi 14-16 part, Radix Platycodonis 14-16 part, Radix Scutellariae 14-16 part, Radix Saposhnikoviae 14-16 part, Rhizoma Chuanxiong 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Bombyx Batryticatus 4-6 part, Semen Arecae 4-6 part, Radix Glycyrrhizae 4-6 part.
The Chinese medicine preparation of described treatment primary glaucoma, its preferably: the crude drug by following weight portion is made: 25 parts of Spica Prunellaes, 25 parts of the Radix Paeoniae Albas, 25 parts of Concha Margaritiferas, 25 parts of Herba Plantaginiss, 20 parts of Radix Bupleuri, 20 parts of Radix Puerariaes, 20 parts of Semen Cassiaes, 20 parts of Flos Chrysanthemis, 15 parts of Radix Rehmanniae Preparata, 15 parts of Rhizoma Alismatis, 10 parts of Radix Angelicae Sinensis, 10 parts of Pheretimas, 10 parts of Rhizoma Cyperis, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Rhizoma Smilacis Glabraes, 10 parts of Ramulus Cinnamomi, 10 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 10 parts of Radix Saposhnikoviaes, 5 parts of Rhizoma Chuanxiongs, 5 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Bombyx Batryticatus, 5 parts of Semen Arecaes, 5 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine preparation for the treatment of primary glaucoma according to claim 1 and 2, is characterized in that: Chinese medicinal preparation method is routinely made oral decoction.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
Spica Prunellae: meridian distribution of property and flavor: pungent, bitter, cold, return liver, gallbladder meridian; Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.
The Radix Paeoniae Alba: meridian distribution of property and flavor: bitter, acid, cool, return liver, spleen channel; Effect: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Concha Margaritifera: meridian distribution of property and flavor: salty, cold, return liver, heart channel; Effect: suppressing the hyperactive liver and subsiding YANG, arresting convulsion improving eyesight.
Herba Plantaginis: meridian distribution of property and flavor: sweet, cold, return liver, lung, kidney, small intestine meridian; Effect: clearing away heat and promoting diuresis, eliminate the phlegm, removing heat from blood, removing toxic substances.
Radix Bupleuri: meridian distribution of property and flavor: bitter, be slightly cold, return liver, gallbladder meridian; Effect: and in table solution, soothing the liver, yang invigorating.
Radix Puerariae: meridian distribution of property and flavor: sweet, pungent, cool, return spleen, stomach warp; Effect: expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, yang invigorating antidiarrheal.
Semen Cassiae: meridian distribution of property and flavor: sweet, bitter, salty, be slightly cold, return liver, large intestine channel; Effect: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.
Flos Chrysanthemi: meridian distribution of property and flavor: sweet, bitter, pungent, be slightly cold, return liver, lung meridian; Effect: wind and heat dispersing, removing toxic substances, improving eyesight.
Radix Rehmanniae Preparata: meridian distribution of property and flavor: bitter, tepor, return liver, kidney channel; Effect: nourishing YIN and supplementing blood, beneficial essence is filled out marrow.
Rhizoma Alismatis: meridian distribution of property and flavor: sweet, cold, return kidney, urinary bladder channel; Effect: diuresis, clearing away damp-heat.
Radix Angelicae Sinensis: meridian distribution of property and flavor: sweet, pungent, warm, return spleen, the heart, Liver Channel; Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Pheretima: meridian distribution of property and flavor: salty, cold, return liver, spleen, urinary bladder channel; Effect: heat clearing away arresting convulsion, dredging collateral, relievings asthma, diuresis.
Rhizoma Cyperi: meridian distribution of property and flavor: pungent, micro-hardship, micro-sweet, flat, return liver, spleen, tri-jiao channel; Effect: liver, spleen, tri-jiao channel.
Ramulus Uncariae Cum Uncis: meridian distribution of property and flavor: sweet, cool, GUIXIN bag, Liver Channel; Effect: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.
Rhizoma Smilacis Glabrae: meridian distribution of property and flavor: sweet, light, flat, return liver, stomach warp; Effect: dehumidifying, removing toxic substances, easing joint movement.
Ramulus Cinnamomi: meridian distribution of property and flavor: pungent, sweet, warm, GUIXIN, lung, urinary bladder channel; Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.
Radix Platycodonis: meridian distribution of property and flavor: pungent, bitter, flat, return lung meridian; Effect: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.
Radix Scutellariae: meridian distribution of property and flavor: bitter, cold, return lung, gallbladder, spleen, large intestine, small intestine meridian; Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
Radix Saposhnikoviae: meridian distribution of property and flavor: sweet, pungent, tepor, return spleen, bladder, Liver Channel; Effect: expelling pathogenic wind from the body surface, victory is wet, pain relieving, spasmolytic.
Rhizoma Chuanxiong: meridian distribution of property and flavor: pungent, warm, return liver, gallbladder, pericardium channel; Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.
Endothelium Corneum Gigeriae Galli: meridian distribution of property and flavor: sweet, flat, return spleen, stomach, small intestinal, urinary bladder channel; Effect: help digestion long-pending, arresting enursis, the inducing decomposition of calculi.
Bombyx Batryticatus: meridian distribution of property and flavor: salty, pungent, flat, return liver, lung, stomach warp; Effect: expelling wind for relieving convulsion, dissipating phlegm and resolving masses.
Semen Arecae: meridian distribution of property and flavor: bitter, pungent, warm, return stomach, large intestine channel; Effect: expelling intestinal worms and removing food stagnancy, sending down the abnormal ascending QI, row water.
Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The beneficial effect that the present invention compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience guidance, choose each crude drug and proportioning thereof, there is the function of nourshing blood and promoting blood circulation, disperse blood stasis and dredge collateral, calming liver and clearing heat, diuretic myosis, realize the object of radical cure primary glaucoma.
Below in conjunction with clinical experiment, beneficial effect of the present invention is described:
(1) clinical data: the present invention treats Endothelium in Patients with Primary Glaucoma 65 examples altogether, wherein male 26 examples, female's 39 examples, the age is 40-70 year.
(2) Therapeutic Method: Chinese medicine decoction of the present invention, 1 pair of every day, point take for 2 times, early, respectively take 1 evening, within 10 days, is 1 course for the treatment of.
(3) the standard of curative effect evaluation:
Cure: intraocular pressure recovers lower than 21mmHg.
Take a turn for the better: intraocular pressure drops to 21-24mmHg, and the ocular hypotensive agents of adding some points can normal.
Do not heal: intraocular pressure does not fall, all diseases of eye and General Symptoms are without improvement.
(4) therapeutic outcome: the present invention treats Endothelium in Patients with Primary Glaucoma 65 examples altogether, through the treatment of 1-4 the course for the treatment of, cures 34 examples, accounts for 52.3%, and 29 examples that take a turn for the better, account for 44.6%, and 2 examples that do not heal, account for 3.1%, and effective percentage is 96.9%, has no any side effect; Cure 34 examples, cure 3 examples 1 course for the treatment of, cure 8 examples 2 courses for the treatment of, cure 11 examples 3 courses for the treatment of, cure 12 examples 4 courses for the treatment of, result shows, the present invention has advantages of good effect, instant effect, has no side effect, is difficult for recurrence.
(5) model case:
1, week so-and-so, man, 68 years old, left eye blurred vision, time have stain or block to block sight line, time little when large, around have blush depending on lamp, time feel caligation mist, very distending pain of the head and eyes, pupil of left eye is loose large, and sclera is micro-red, vexed bitter taste, impatient irritability, red tongue, the micro-Huang of tongue, stringy,thready and rapid pulse, is blind in the left eye more than 10 years, is diagnosed as primary glaucoma; After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, cure.
2, Wang, female, 46 years old, often headache, left eye distending pain, nausea and vomiting, has iridization depending on light, existing 8 years of eye dusk, angry irritated and increase the weight of whenever, check: about 4 millimeters of pupil of left eye, light reflex is blunt, and optical fundus papilla of optic nerve glaucoma depression is obviously, the tortuous anger of vein is opened, and blood vessel is the shape of going down on one's knees, and macular area is slightly dark, vision 0.3, intraocular pressure 46 millimetress of mercury, right eye is normal, have uncomfortable in chest, hypochondriac pain, bitter taste in the mouth and dry throat, red tongue, yellow fur, rapid pulse, be diagnosed as primary glaucoma; Take after 1 course for the treatment of of Chinese medicine preparation of the present invention, ophthalmic bloated alleviation of pain is light, and vision is promoted, and continues to take 1 course for the treatment of of Chinese medicine preparation of the present invention, has an eyesight test 0.9, intraocular pressure 17 millimetress of mercury, and all illness are removed entirely, follow up a case by regular visits to not recurrence in 1 year.
3, Xing so-and-so, man, 43 years old, suffer from primary glaucoma, intraocular pressure raise, eyeball distending pain, blurred vision; Take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, all diseases alleviate, and continue to take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, and vision brings up to 0.9 by original 0.4, and eyeball distending pain disappears, and cures, so far not recurrence.
4, Hu, female, 46 years old, suffer from primary glaucoma, eyes keep in dark place, shed tears, like and rub one's eyes, the symptom such as, vomiting poor with diet, hyperhidrosis; Take after 1 course for the treatment of of Chinese medicine preparation of the present invention, shed tears, vomiting stops, and continues to take Chinese medicine preparation of the present invention and cures 2 courses for the treatment of, follows up a case by regular visits to not recurrence in 1 year.
The specific embodiment
Embodiment 1:
Treat a Chinese medicine preparation for primary glaucoma, made by the crude drug of following weight portion: 25 parts of Spica Prunellaes, 25 parts of the Radix Paeoniae Albas, 25 parts of Concha Margaritiferas, 25 parts of Herba Plantaginiss, 20 parts of Radix Bupleuri, 20 parts of Radix Puerariaes, 20 parts of Semen Cassiaes, 20 parts of Flos Chrysanthemis, 15 parts of Radix Rehmanniae Preparata, 15 parts of Rhizoma Alismatis, 10 parts of Radix Angelicae Sinensis, 10 parts of Pheretimas, 10 parts of Rhizoma Cyperis, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Rhizoma Smilacis Glabraes, 10 parts of Ramulus Cinnamomi, 10 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 10 parts of Radix Saposhnikoviaes, 5 parts of Rhizoma Chuanxiongs, 5 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Bombyx Batryticatus, 5 parts of Semen Arecaes, 5 parts, Radix Glycyrrhizae.
Its preparation method is: Chinese medicinal preparation method is routinely made oral decoction.
Embodiment 2:
A kind of Chinese medicine preparation for the treatment of primary glaucoma, crude drug by following weight portion is made: Spica Prunellae 23-27 part, Radix Paeoniae Alba 23-27 part, Concha Margaritifera 23-27 part, Herba Plantaginis 23-27 part, Radix Bupleuri 18-22 part, Radix Puerariae 18-22 part, Semen Cassiae 18-22 part, Flos Chrysanthemi 18-22 part, Radix Rehmanniae Preparata 14-16 part, Rhizoma Alismatis 14-16 part, Radix Angelicae Sinensis 14-16 part, Pheretima 14-16 part, Rhizoma Cyperi 14-16 part, Ramulus Uncariae Cum Uncis 14-16 part, Rhizoma Smilacis Glabrae 14-16 part, Ramulus Cinnamomi 14-16 part, Radix Platycodonis 14-16 part, Radix Scutellariae 14-16 part, Radix Saposhnikoviae 14-16 part, Rhizoma Chuanxiong 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Bombyx Batryticatus 4-6 part, Semen Arecae 4-6 part, Radix Glycyrrhizae 4-6 part.
Its preparation method is: Chinese medicinal preparation method is routinely made oral decoction.
Embodiment 3:
A kind of Chinese medicine preparation for the treatment of primary glaucoma, crude drug by following weight portion is made: Spica Prunellae 23-27 part, Radix Paeoniae Alba 23-27 part, Concha Margaritifera 23-27 part, Herba Plantaginis 23-27 part, Radix Bupleuri 18-22 part, Radix Puerariae 18-22 part, Semen Cassiae 18-22 part, Flos Chrysanthemi 18-22 part, Radix Rehmanniae Preparata 14-16 part, Rhizoma Alismatis 14-16 part, Radix Angelicae Sinensis 14-16 part, Pheretima 14-16 part, Rhizoma Cyperi 14-16 part, Ramulus Uncariae Cum Uncis 14-16 part, Rhizoma Smilacis Glabrae 14-16 part, Ramulus Cinnamomi 14-16 part, Radix Platycodonis 14-16 part, Radix Scutellariae 14-16 part, Radix Saposhnikoviae 14-16 part, Rhizoma Chuanxiong 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Bombyx Batryticatus 4-6 part, Semen Arecae 4-6 part, Radix Glycyrrhizae 4-6 part.
Its preparation method is: Chinese medicinal preparation method is routinely made oral decoction.
Claims (3)
1. treat the Chinese medicine preparation of primary glaucoma for one kind, it is characterized in that: the crude drug by following weight portion is made: Spica Prunellae 23-27 part, Radix Paeoniae Alba 23-27 part, Concha Margaritifera 23-27 part, Herba Plantaginis 23-27 part, Radix Bupleuri 18-22 part, Radix Puerariae 18-22 part, Semen Cassiae 18-22 part, Flos Chrysanthemi 18-22 part, Radix Rehmanniae Preparata 14-16 part, Rhizoma Alismatis 14-16 part, Radix Angelicae Sinensis 14-16 part, Pheretima 14-16 part, Rhizoma Cyperi 14-16 part, Ramulus Uncariae Cum Uncis 14-16 part, Rhizoma Smilacis Glabrae 14-16 part, Ramulus Cinnamomi 14-16 part, Radix Platycodonis 14-16 part, Radix Scutellariae 14-16 part, Radix Saposhnikoviae 14-16 part, Rhizoma Chuanxiong 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Bombyx Batryticatus 4-6 part, Semen Arecae 4-6 part, Radix Glycyrrhizae 4-6 part.
2. the Chinese medicine preparation for the treatment of primary glaucoma according to claim 1, is characterized in that: the crude drug by following weight portion is made: 25 parts of Spica Prunellaes, 25 parts of the Radix Paeoniae Albas, 25 parts of Concha Margaritiferas, 25 parts of Herba Plantaginiss, 20 parts of Radix Bupleuri, 20 parts of Radix Puerariaes, 20 parts of Semen Cassiaes, 20 parts of Flos Chrysanthemis, 15 parts of Radix Rehmanniae Preparata, 15 parts of Rhizoma Alismatis, 10 parts of Radix Angelicae Sinensis, 10 parts of Pheretimas, 10 parts of Rhizoma Cyperis, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Rhizoma Smilacis Glabraes, 10 parts of Ramulus Cinnamomi, 10 parts of Radix Platycodoniss, 10 parts of Radix Scutellariaes, 10 parts of Radix Saposhnikoviaes, 5 parts of Rhizoma Chuanxiongs, 5 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Bombyx Batryticatus, 5 parts of Semen Arecaes, 5 parts, Radix Glycyrrhizae.
3. the preparation method of the Chinese medicine preparation for the treatment of primary glaucoma according to claim 1 and 2, is characterized in that: Chinese medicinal preparation method is routinely made oral decoction.
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| CN201410092088.4A CN103830513B (en) | 2014-03-13 | 2014-03-13 | A kind of Chinese medicine preparation for the treatment of primary glaucoma |
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| CN201410092088.4A CN103830513B (en) | 2014-03-13 | 2014-03-13 | A kind of Chinese medicine preparation for the treatment of primary glaucoma |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398730A (en) * | 2014-12-02 | 2015-03-11 | 四川金堂海纳生物医药技术研究所 | Internally-taken medicament for treating primary glaucoma and preparation method thereof |
| CN105434946A (en) * | 2015-12-26 | 2016-03-30 | 卢文华 | Medicine for treating glaucoma and preparation method of medicine |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101112604A (en) * | 2007-08-20 | 2008-01-30 | 山西医科大学第二医院 | Medicine for treating glaucoma and method for preparing the same |
| CN103446379A (en) * | 2012-05-30 | 2013-12-18 | 孔祥军 | Oral traditional Chinese medicine decoction for treating glaucoma |
-
2014
- 2014-03-13 CN CN201410092088.4A patent/CN103830513B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101112604A (en) * | 2007-08-20 | 2008-01-30 | 山西医科大学第二医院 | Medicine for treating glaucoma and method for preparing the same |
| CN103446379A (en) * | 2012-05-30 | 2013-12-18 | 孔祥军 | Oral traditional Chinese medicine decoction for treating glaucoma |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398730A (en) * | 2014-12-02 | 2015-03-11 | 四川金堂海纳生物医药技术研究所 | Internally-taken medicament for treating primary glaucoma and preparation method thereof |
| CN105434946A (en) * | 2015-12-26 | 2016-03-30 | 卢文华 | Medicine for treating glaucoma and preparation method of medicine |
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