CN104013831A - Medicament for treating insufficient blood supply - Google Patents
Medicament for treating insufficient blood supply Download PDFInfo
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- CN104013831A CN104013831A CN201410244929.9A CN201410244929A CN104013831A CN 104013831 A CN104013831 A CN 104013831A CN 201410244929 A CN201410244929 A CN 201410244929A CN 104013831 A CN104013831 A CN 104013831A
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Abstract
The invention discloses a medicament for treating insufficient blood supply. The medicament is prepared from the following traditional Chinese medicines in parts by weight as crude medicinal materials: 50-80 parts of root of kudzu vine, 10-20 parts of fried fructus viticis, 15-30 parts of astragalus membranaceus, 20-40 parts of salviae miltiorrhizae, 15-30 parts of parched white peony root, 15-30 parts of ligusticum wallichii, 5-15 parts of scorpion, 10-20 parts of pseudo-ginseng, 15-30 parts of gastrodia elata, 15-30 parts of radix cyathulae and 15-30 parts of fruit of Chinese wolfberry. The medicament disclosed by the invention has the functions of replenishing qi and elevating yang, and invigorating circulation of blood and dredging veins, and is mainly used for treating the diseases such as megrim, dizziness, headache, neck stiffness, upper lime and finger numbness and the like caused by insufficient blood supply. The total effective rate is 90% by clinical curative effect observation.
Description
Technical field
The present invention relates to treat the medicine of cerebral blood supply insufficiency, particularly relate to a kind of medicine of take the treatment cerebral blood supply insufficiency that Chinese medicine is crude drug.
Background technology
Cerebral blood supply insufficiency refers to the disordered brain function that a certain local blood of human brain is under-supply and cause.The cause of disease of cerebral blood supply insufficiency is main relevant with cerebral arteriosclerosis, and in addition, the blood supply disorder causing because of cervical spondylosis is also one of Etiological of cerebral blood supply insufficiency.
Chronic insufficient cerebral blood supply (CCCI) nineteen ninety is proposed by Japanese health ministry blood circulation diseases tutorial class, the 16th apoplexy association definite designation of Japan in 1991, refer to that the blood supply per minute of brain integral level reduces the state of (lower than 40～60ml/100g cerebral tissue), it develops the generation that very easily causes senile dementia and apoplexy gradually.
Can there is the symptoms such as headache, dizzy, tinnitus, numb limbs and tense tendons, memory obviously go down in cerebral blood supply insufficiency patient.Therapeutic Method can be divided into the symptomatic treatment that directly improves the blood supply of the brain heart, and the etiological treatment that stops arteriosclerosis process and elimination stenosis occlusion blood vessel.Mainly apply clinically following a few class medicines: 1, vasodilation; 2, anticoagulant and anti-platelet aggregation agent; 3, thrombolytic agent; 4, encephaledema and reduction brain metabolic drug.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of cerebral blood supply insufficiency, that treatment is caused by cerebral blood supply insufficiency is dizzy, dizzy, have a headache, rigidity of the neck, and upper limb, numbness of the fingers texts are remarkable.
The medicine for the treatment of cerebral blood supply insufficiency of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:
Radix Puerariae 50～80 stir-baked FRUCTUS VITICIS 10～20 Radixs Astragali 15～30
Radix Salviae Miltiorrhizae 20～40 Radix Paeoniae Alba (parched) 15～30 Rhizoma Chuanxiongs 15～30
Scorpio 5～15 Radix Notoginseng 10～20 Rhizoma Gastrodiaes 15～30
Radix Cyathulae 15～30 Fructus Lycii 15～30.
Pharmic function benefiting qi and raising yang of the present invention, blood circulation and channel invigorating, be mainly used in dizzy, dizzy, headache that treatment causes due to cerebral blood supply insufficiency, rigidity of the neck, the diseases such as upper limb, numbness of the fingers.
The preparation method of medicine of the present invention is: the crude drug of above parts by weight, and Rhizoma Gastrodiae powder is broken into fine powder; Radix Puerariae, Radix Salviae Miltiorrhizae ethanol percolation, collect percolate, reclaims ethanol, is condensed into clear paste; After percolation, medicinal residues and other 8 kinds of crude drug decoct with water 2 times, and each 2 hours, collecting decoction, filtered, and filtrate is condensed into clear paste; Merge with above-mentioned percolate clear paste, be concentrated into thick paste shape, add above-mentioned Rhizoma Gastrodiae fine powder, mix, dry, pulverize into fine powder, in incapsulating, make.
Cerebral blood supply insufficiency belongs to the traditional Chinese medical science " dizzy " category, and theory of Chinese medical science thinks that the kidney generating marrow and dominating bone leads in brain, Kidney-Yin, the kidney-Yang of residence in kidney, kidney controlling essence storage.In < <, through > >, claim brain being the marrow sea, so-called extra large person is poly-marrow part, the institute of non-raw marrow.Study carefully its source person, real gasification Kidney-Yin in kidney, kidney-Yang is closed and is formed, and the vital essence of kidney is followed governor vessel and risen and be directed to brain, and brain must be filled.Old deficiency of the kidney, or the kidney usually involved in chronic disease, or impairment of the kidney due to indulgence in sexual activities, kidney-jing deficiency consumption, can not give birth to marrow, and brain being the marrow sea, deficiency of marrow-reservoir is sent out as dizzy.Therefore, the deficiency of the kidney deficiency of vital energy, congestion expectorant is turbid is its Etiological pathogenesis, should benefiting qi and raising yang in treatment, blood circulation and channel invigorating.
In prescription of the present invention, Radix Puerariae, Radix Astragali benefiting qi and raising yang; Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Cyathulae blood circulation and channel invigorating; Rhizoma Gastrodiae, Scorpio relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and reduce phlegm, and Fructus Lycii, Radix Paeoniae Alba (parched) adjusting and reinforcing liver and kidney help marrow perfusion brains, and stir-baked FRUCTUS VITICIS helps the improving eyesight of Radix Puerariae yang invigorating, and the Radix Notoginseng blood stasis dispelling of nourishing blood, has the wonderful of crucial touch.The merit that full side plays benefiting qi and raising yang, blood circulation and channel invigorating altogether, be used for the treatment of dizzy, dizzy, headache, rigidity of the neck, the diseases such as upper limb, numbness of the fingers, for because cervical spondylosis, cerebral blood vessel elasticity go down, due to hypertension, cerebral infarction sequela, sclerencephaly QI and blood can not on reach at head person all have specially good effect.
Medicine of the present invention not only can be eliminated cerebral blood supply insufficiency symptom, to delaying middle-aged and elderly people aging, has positive effect, and also has the effect of prevention and health care.
The present invention selects 150 routine cerebral blood supply insufficiency patients to carry out the curative effect clinical observation of medicine of the present invention, with the effectiveness to medicine of the present invention, makes scientific evaluation.
Described patient all meets the chronic insufficient cerebral blood supply diagnostic criteria of nineteen ninety Japanese health ministry blood circulation diseases tutorial class proposition.Male 86 examples wherein, female's 64 examples; 60～85 years old age, average 72 years old; The course of disease 3 months～2 years.
1. there is the subjective symptoms that disturbance of cerebral circulation causes (headache, dizzy etc.).2. the focal location sign of anencephaly.3. many with hypertension.4. there is ocular fundus arteriosclerosis.5. sometimes can hear vascular murmur at the perfusion tremulous pulse of brain.6.CT or MRA check without cerebrovascular organic disease.7. the above-mentioned symptom that definite eliminating Other diseases causes.
Therapeutic Method: take medicament capsule of the present invention, every day 2 times, each 3～5.Continuous use 4 weeks is 1 course for the treatment of.Finish its curative effect of rear judgement the course for the treatment of.
Efficacy assessment standard: 1. effective, clinical symptom disappearance, cerebrovascular shows brain perfusion tremulous pulse non-blocking, narrow according to shadow or TCD inspection; 2. effective, clinical symptoms is clearly better, and cerebrovascular shows brain perfusion arterial occlusion, narrow obvious improvement according to shadow or TCD inspection; 3. invalid, clinical symptoms is not improved or increases the weight of, and cerebrovascular shows that according to shadow or TCD inspection brain perfusion arterial occlusion, stenotic lesion are without improvement.
After 150 routine patients finish the course for the treatment of, effective 45 examples, effective 90 examples, invalid 15 examples, total effective rate 90%.
The specific embodiment
Embodiment 1
Getting Rhizoma Gastrodiae 2Kg, to be ground into fine powder stand-by.
Get Radix Puerariae 6Kg, Radix Salviae Miltiorrhizae 3Kg, with ethanol, carry out percolation, collect percolate, reclaim after ethanol, be condensed into relative density 1.1(60 ℃) clear paste stand-by.
Medicinal residues after percolation are mixed with stir-baked FRUCTUS VITICIS 1.5Kg, Radix Astragali 2Kg, Radix Paeoniae Alba (parched) 2Kg, Rhizoma Chuanxiong 2Kg, Scorpio 1Kg, Radix Notoginseng 1.5Kg, Radix Cyathulae 2Kg, Fructus Lycii 2Kg, decoct with water twice, each 2 hours, collecting decoction, filter, filtrate is condensed into relative density 1.1(60 ℃) clear paste, merge with above-mentioned percolate clear paste, be concentrated into thick paste shape, add above-mentioned Rhizoma Gastrodiae fine powder, mix, dry, be ground into fine powder, in incapsulating, make medicine.
Embodiment 2
Getting Rhizoma Gastrodiae 2.5Kg, to be ground into fine powder stand-by.
Get Radix Puerariae 5Kg, Radix Salviae Miltiorrhizae 2.5Kg, with ethanol, carry out percolation, collect percolate, reclaim after ethanol, be condensed into relative density 1.1(60 ℃) clear paste stand-by.
Medicinal residues after percolation are mixed with stir-baked FRUCTUS VITICIS 1Kg, Radix Astragali 2.5Kg, Radix Paeoniae Alba (parched) 2.5Kg, Rhizoma Chuanxiong 2.5Kg, Scorpio 1.5Kg, Radix Notoginseng 1Kg, Radix Cyathulae 1.5Kg, Fructus Lycii 1.5Kg, decoct with water twice, each 2 hours, collecting decoction, filter, filtrate is condensed into relative density 1.1(60 ℃) clear paste, merge with above-mentioned percolate clear paste, be concentrated into thick paste shape, add above-mentioned Rhizoma Gastrodiae fine powder, mix, dry, be ground into fine powder, in incapsulating, make medicine.
Embodiment 3
Getting Rhizoma Gastrodiae 1.5Kg, to be ground into fine powder stand-by.
Get Radix Puerariae 7.5Kg, Radix Salviae Miltiorrhizae 4Kg, with ethanol, carry out percolation, collect percolate, reclaim after ethanol, be condensed into relative density 1.1(60 ℃) clear paste stand-by.
Medicinal residues after percolation are mixed with stir-baked FRUCTUS VITICIS 2Kg, Radix Astragali 1.5Kg, Radix Paeoniae Alba (parched) 1.5Kg, Rhizoma Chuanxiong 1.5Kg, Scorpio 1Kg, Radix Notoginseng 2Kg, Radix Cyathulae 3Kg, Fructus Lycii 3Kg, decoct with water twice, each 2 hours, collecting decoction, filter, filtrate is condensed into relative density 1.1(60 ℃) clear paste, merge with above-mentioned percolate clear paste, be concentrated into thick paste shape, add above-mentioned Rhizoma Gastrodiae fine powder, mix, dry, be ground into fine powder, in incapsulating, make medicine.
Claims (2)
1. treating a medicine for cerebral blood supply insufficiency, is that the Chinese medicine by following parts by weight is that crude drug prepares:
Radix Puerariae 50～80 stir-baked FRUCTUS VITICIS 10～20 Radixs Astragali 15～30
Radix Salviae Miltiorrhizae 20～40 Radix Paeoniae Alba (parched) 15～30 Rhizoma Chuanxiongs 15～30
Scorpio 5～15 Radix Notoginseng 10～20 Rhizoma Gastrodiaes 15～30
Radix Cyathulae 15～30 Fructus Lycii 15～30.
2. the preparation method of the medicine of claim 1 treatment cerebral blood supply insufficiency, is the crude drug with described parts by weight, and Rhizoma Gastrodiae powder is broken into fine powder; Radix Puerariae, Radix Salviae Miltiorrhizae ethanol percolation, collect percolate, reclaims ethanol, is condensed into clear paste; After percolation, medicinal residues and other 8 kinds of crude drug decoct with water 2 times, and each 2 hours, collecting decoction, filtered, and filtrate is condensed into clear paste; Merge with above-mentioned percolate clear paste, be concentrated into thick paste shape, add above-mentioned Rhizoma Gastrodiae fine powder, mix, dry, pulverize into fine powder, in incapsulating, make.
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| CN201410244929.9A CN104013831B (en) | 2014-06-05 | 2014-06-05 | A kind of medicine for treating cerebral blood supply insufficiency |
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| CN201410244929.9A CN104013831B (en) | 2014-06-05 | 2014-06-05 | A kind of medicine for treating cerebral blood supply insufficiency |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105833184A (en) * | 2016-05-09 | 2016-08-10 | 三峡大学 | Traditional Chinese medicine composition, fermented medicine liquor prepared from traditional Chinese medicine composition, preparation method and application |
Citations (3)
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| CN1451402A (en) * | 2002-04-16 | 2003-10-29 | 王亚东 | Chinese medicinal preparation for treating cadiovascular and cerebrovascular diseases |
| US20070053999A1 (en) * | 2003-09-23 | 2007-03-08 | Feng Wei | Pharmaceutical composition for the treatment of cardiovascular and cerebrovascular diseases |
| CN103007064A (en) * | 2012-12-31 | 2013-04-03 | 尚欣 | Traditional Chinese medicine (TCM) composition for treating cerebral posterior circulation ischemia |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1451402A (en) * | 2002-04-16 | 2003-10-29 | 王亚东 | Chinese medicinal preparation for treating cadiovascular and cerebrovascular diseases |
| US20070053999A1 (en) * | 2003-09-23 | 2007-03-08 | Feng Wei | Pharmaceutical composition for the treatment of cardiovascular and cerebrovascular diseases |
| CN103007064A (en) * | 2012-12-31 | 2013-04-03 | 尚欣 | Traditional Chinese medicine (TCM) composition for treating cerebral posterior circulation ischemia |
Non-Patent Citations (3)
| Title |
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| 李广浩等: "中医药治疗眩晕研究近况", 《中国中医急症》 * |
| 杨锋等: "《脑血管病妙方特技精粹》", 28 February 2001, 人民军医出版社 * |
| 饶娆等: "慢性脑供血不足的中医药治疗", 《中医药临床杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105833184A (en) * | 2016-05-09 | 2016-08-10 | 三峡大学 | Traditional Chinese medicine composition, fermented medicine liquor prepared from traditional Chinese medicine composition, preparation method and application |
| CN105833184B (en) * | 2016-05-09 | 2019-07-26 | 三峡大学 | A kind of Chinese medicine composition, fermentation medical fluid of its preparation and preparation method and application |
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| CN104013831B (en) | 2017-06-23 |
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